CN104641222A - 用于发光显微成像的双向扫描 - Google Patents

用于发光显微成像的双向扫描 Download PDF

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Publication number
CN104641222A
CN104641222A CN201380028512.2A CN201380028512A CN104641222A CN 104641222 A CN104641222 A CN 104641222A CN 201380028512 A CN201380028512 A CN 201380028512A CN 104641222 A CN104641222 A CN 104641222A
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CN
China
Prior art keywords
target
view
wide field
luminescence
interrogation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201380028512.2A
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English (en)
Chinese (zh)
Inventor
金大勇
陆怡青
詹姆士·奥斯汀·皮珀
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Macquarie University
Original Assignee
Macquarie University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012902232A external-priority patent/AU2012902232A0/en
Application filed by Macquarie University filed Critical Macquarie University
Publication of CN104641222A publication Critical patent/CN104641222A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/16—Microscopes adapted for ultraviolet illumination ; Fluorescence microscopes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/10—Scanning

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
CN201380028512.2A 2012-05-29 2013-05-28 用于发光显微成像的双向扫描 Pending CN104641222A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2012902232 2012-05-29
AU2012902232A AU2012902232A0 (en) 2012-05-29 Two-directional scanning for luminescence microscopy
PCT/AU2013/000559 WO2013177617A1 (en) 2012-05-29 2013-05-28 Two-directional scanning for luminescence microscopy

Publications (1)

Publication Number Publication Date
CN104641222A true CN104641222A (zh) 2015-05-20

Family

ID=49672176

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380028512.2A Pending CN104641222A (zh) 2012-05-29 2013-05-28 用于发光显微成像的双向扫描

Country Status (5)

Country Link
US (1) US20150144806A1 (enExample)
EP (1) EP2856117A4 (enExample)
CN (1) CN104641222A (enExample)
IN (1) IN2014MN02311A (enExample)
WO (1) WO2013177617A1 (enExample)

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CN105891170B (zh) * 2015-02-16 2019-07-05 北京大学 活体动物双光子激发延时检测荧光成像分析方法及设备
JP6516583B2 (ja) * 2015-06-22 2019-05-22 パナソニック株式会社 半導体試料の結晶欠陥検出装置及び結晶欠陥検出方法
CN109154551B (zh) * 2015-12-30 2021-05-14 生物辐射实验室股份有限公司 用于颗粒测定的检测和信号处理系统
US10627490B2 (en) 2016-01-31 2020-04-21 Velodyne Lidar, Inc. Multiple pulse, LIDAR based 3-D imaging
JP7149256B2 (ja) 2016-03-19 2022-10-06 ベロダイン ライダー ユーエスエー，インコーポレイテッド Ｌｉｄａｒに基づく３次元撮像のための統合された照射及び検出
WO2017210418A1 (en) 2016-06-01 2017-12-07 Velodyne Lidar, Inc. Multiple pixel scanning lidar
CN110914705B (zh) 2017-03-31 2024-04-26 威力登激光雷达美国有限公司 用于集成lidar照明功率控制的设备、系统和方法
CN115575928A (zh) 2017-05-08 2023-01-06 威力登激光雷达美国有限公司 Lidar数据获取与控制
US11294041B2 (en) * 2017-12-08 2022-04-05 Velodyne Lidar Usa, Inc. Systems and methods for improving detection of a return signal in a light ranging and detection system
US11971507B2 (en) 2018-08-24 2024-04-30 Velodyne Lidar Usa, Inc. Systems and methods for mitigating optical crosstalk in a light ranging and detection system
US10712434B2 (en) 2018-09-18 2020-07-14 Velodyne Lidar, Inc. Multi-channel LIDAR illumination driver
US11082010B2 (en) 2018-11-06 2021-08-03 Velodyne Lidar Usa, Inc. Systems and methods for TIA base current detection and compensation
US11885958B2 (en) 2019-01-07 2024-01-30 Velodyne Lidar Usa, Inc. Systems and methods for a dual axis resonant scanning mirror
US12061263B2 (en) 2019-01-07 2024-08-13 Velodyne Lidar Usa, Inc. Systems and methods for a configurable sensor system
US10613203B1 (en) * 2019-07-01 2020-04-07 Velodyne Lidar, Inc. Interference mitigation for light detection and ranging
RU195925U1 (ru) * 2019-11-19 2020-02-11 Федеральное государственное бюджетное образовательное учреждение высшего образования "Рязанский государственный радиотехнический университет имени В.Ф. Уткина" Сканирующий зонд атомно-силового микроскопа с отделяемым телеуправляемым нанокомпозитным излучающим элементом, легированным квантовыми точками, апконвертирующими и магнитными наночастицами структуры ядро-оболочка
CN113075175B (zh) * 2021-03-15 2022-10-14 中国科学院福建物质结构研究所 一种宽波段时间分辨荧光免疫分析装置及分析方法
EP4657133A1 (en) * 2024-05-29 2025-12-03 Leica Microsystems CMS GmbH An optical system for a microscope and a method for operating the microscope

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EP2856117A1 (en) 2015-04-08
EP2856117A4 (en) 2016-02-17
WO2013177617A1 (en) 2013-12-05
US20150144806A1 (en) 2015-05-28
IN2014MN02311A (enExample) 2015-08-07

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