CN104623644A - Gel suppository for cleaning of women - Google Patents
Gel suppository for cleaning of women Download PDFInfo
- Publication number
- CN104623644A CN104623644A CN201410745875.4A CN201410745875A CN104623644A CN 104623644 A CN104623644 A CN 104623644A CN 201410745875 A CN201410745875 A CN 201410745875A CN 104623644 A CN104623644 A CN 104623644A
- Authority
- CN
- China
- Prior art keywords
- weight
- women
- sod
- gel
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a gel suppository for cleaning of women, which has the functions of regulating the pH value of woman's vagina, eliminating various s bacteria and moulds inducing the inflammations of women's reproductive systems, and reestablishing the autoimmunity of women. The suppository comprises small molecule water, dihydromyricetin, chlorogenic acid, resveratrol, glutathione, SOD (superoxide dismutase), vitamin C, hyaluronic acid, myrrh essential oil, silver oxide nanoparticles, gels, and the like.
Description
Technical field
The present invention relates to a kind of women's cleansing gel suppository for woman vagina, relate to one in particular and there is adjustment woman vagina pH value, eliminate the various antibacterial and the mycete that cause inflammation of woman genetic system, rebuild a kind of women's cleansing gel suppository of women's autoimmune function.
Technical background
In the last few years, market occurs multiple women cleans the preparation of reproductive system, but the boots of a lot of preparation are indefinite to effect, unsuitable disinfectant component often destroys again the pH environment of the reproductive system of women, also destroys the autoimmune system of women.Often bring more complicated symptom to women.The Chinese medicine preparation of some synthesis, the active ingredient do not determined, arbitrarily enters in the body of women with mixing, may cause otherwise injury on the contrary.
Summary of the invention
No matter what age bracket of women all likely colpitis occurs, women vaginitis is the inflammation of connective tissue under vaginal mucosa and mucosa, is the common disease of gynecological.Normal healthy women, due to anatomy and biochemical characteristics, the intrusion of vagina to pathogen has nature defense function, when the natural defense function of vagina is destroyed, then pathogen is easy to invade, cause colpitis, youngest daughter and postmenopausal women are due to estrogen deficiency, and vagina epithelium is belittled, the former content of endocellular sugar reduces, vagina pH is up to about 7, therefore vagina is lower for the resistance, than adolescence and the women of child-bearing age easily infected.Vaginitis changes with the character of leucorrhea clinically and pudendum infections itches causalgia for Major Clinical feature, and sexual anhedonia is also common, when urethra is involved in infection, can have the symptom such as dysurea, urgent micturition.Common vaginitis has bacterial vaginitis, trichomonal vaginitis, colpitis mycotica, senile vaginitis.Due to inflammation, make intravaginal produce a large amount of free radicals, free radical comprises ultra-oxygen anion free radical
with hydroxy radical OH
., the appearance of free radical, by connective tissue under serious injury vaginal mucosa and mucosa.Adult women and the women through producing, it is lax that vagina has in various degree, so more be conducive to the female genital system inside of driving straight in of various antibacterial and mycete, cause uterus, ovary, the inflammation of fallopian tube urinary system and pelvic cavity and hyperemia further, bring very large misery to women.
In order to remove pain disease and the painful topic of women, we adopt following component: micromolecular water; Dihydromyricetin; Resveratrol; Glutathion; Superoxide dismutase (SOD); Vitamin C; Hyaluronic acid; Myrrha quintessence oil; Nano oxidized Argent grain and gel.Gel can add wetting agent, antiseptic, antioxidant, emulsifying agent, thickening agent and transdermal enhancer as required.
Small-micelle water has extraordinary solvability, is rich in oxygen again, the active ingredients in suppository fully can be dissolved in wherein, be supplied to vaginal wall and reproductive system.Also stop the existence of anaerobic bacteria simultaneously.The activity of SOD can also be improved.Band width corresponding to the high point of small-micelle water 17 oxygen nuclear magnetic resonance, NMR amplitude half is 45-80Hz.
Dihydromyricetin: in 25 DEG C of water, dissolubility is 4%, and in hot water, dissolubility is larger; Be soluble in ethanol.Dihydromyricetin all has bacteriostasis to Bacillus subtillis, staphylococcus aureus, salmonella, escherichia coli, aerobacteria, beer yeast, glutinous Rhodothece glutinis, penicillium sp, aspergillus niger, Aspergillus flavus, Mucor and rhizopus, especially obvious to Grain-positive, gram-negative cocci or bacillus effect.
Chlorogenic acid: in 25 DEG C of water, dissolubility is 4%, and in hot water, dissolubility is larger; Be soluble in ethanol.Chlorogenic acid is a kind of important bioactive substance, has antibacterial, antiviral, increases the effects such as leukocyte, antitumor, scavenging free radicals and stimulating central nervous system system.The chlorogenic acid extracted from the Cortex Eucommiae has the function of collapse resistance human immune system virus, and this material may be used for prevention and therapy acquired immune deficiency syndrome (AIDS).
Resveratrol has the effect of Tumor suppression, also has estrogen action, can be used for the diseases such as treatment breast carcinoma.Resveratrol is to golden yellow Fructus Vitis viniferae
coccus, micrococcus catarrhalis, escherichia coli, bacillus pyocyaneus have inhibitory action.Resveratrol is alcohol dissolved substance, during use, is first dissolved with suitable ethanol, then it is mixed with other substance solutions.
Glutathion has antioxidation and integrates Detoxication, soluble in water.
Superoxide dismutase (SOD) can remove ultra-oxygen anion free radical, Cell protection and repair impaired cell diminishing inflammation, and is water-soluble substances.
Vitamin C presents acid material, is antioxidant simultaneously.In the aqueous solution of 5mg/ml, pH value is 3.Oxidation-reduction potential is 0.166V (pH=4).Its water solubility is 40% 45 DEG C time, is 80% 100 DEG C time.Gel can be regulated to be acid state with it, make the pH value 3.5-5.5 that gel presents close to vagina.In gel, play antioxidative effect, and keep the activity of SOD.
In the connective tissue that hyaluronic acid is present in human body in a large number and skin corium, have powerful water absorbing capacity and moisture-keeping functions, the long water holding capacity of skin can also be strengthened, elastic fibers and collagen protein can be helped to be in be full of in the environment of moisture, what allow skin show is more flexible, makes vaginal contraction.
Myrrha quintessence oil: Myrrha quintessence oil is known as " patron saint of genitals ", can sterilize, disinfection force is strong, can suppress scytitis, all effective in cure to pimples eczema.Can dry cracked skin be moistened, also effective to wrinkle, use it can contracting vagina and treatment female urinary incontinence symptom, thus make pudendum cleaning, reduce the chance infected.
Nano oxidized Argent grain in the presence of water, has fabulous eliminating bacteria and the effect of mycete.The effect of antiseptic can also be played in whole gel.
Specific embodiment
Using overall emulsion as 100 % by weight:
Aqueous phase substance is small-micelle water, and band width corresponding to the high point of 17 oxygen nuclear magnetic resonance, NMR amplitudes half is 45-80Hz, has 50 % by weight-70 % by weight;
Fat phase material be selected from olive oil, glycerol, vitamin E oil any one or a few, 20 % by weight-30 % by weight, wherein, vitamin E is fat-soluble, needs to be dissolved with oils and fats;
Epidermal cell repairing material is superoxide dismutase SOD and glutathion, and SOD selects Cu, Zn-SOD, and added SOD amount guarantees that every ml emulsion has 100-800u (enzyme is lived)/ml, glutathion 0.5-2mg/ml;
Moisture and crease-resistant material is kept to be hyaluronic acid, 0.01 % by weight-0.1 % by weight;
Non-ionic surface active agent adopt HLB value to be the sorbitan ester class of 10-18 and HLB value lower than 10 Sorbitan alcohols with the use of, 5 % by weight-8 % by weight;
Thickening agent is selected from polyacrylamide homo polymer or cellulose ether, 0.5% weight-1% weight;
Described penetrating agent is propylene glycol, 5 % by weight-8 % by weight;
Described antioxidant selects vitamin C, and with it the most at last ph value of emulsion adjust between 3.5-5.5.
Described spice is selected from jasmin essence or Oleum Caryophylli, 0.0001 weight-0.001 % by weight.
The material chlorogenic acid of eliminating bacteria and mycete, dihydromyricetin, resveratrol and nano oxidized Argent grain, can use 1-3 kind wherein.
Chlorogenic acid: 0-3000mg;
Dihydromyricetin: 0-3000mg;
Resveratrol: 0-3000mg;
Nano oxidized Argent grain, 0 % by weight-0.01 % by weight;
If use nano oxidized Argent grain, dispersant need be used for diphosphonate ester, 0.0005 % by weight-0.01 % by weight;
Myrrha quintessence oil: 200-2000mg;
In addition also have suitable moulding dose, product can be made to become bullet shaped, make user easily suppository be pushed vagina, disease therapy.
Use women's cleansing gel suppository of the present invention, woman vagina pH value can be adjusted interval at 3.5-5.5, eliminate the various antibacterial and the mycete that cause inflammation of woman genetic system, rebuild women's autoimmune function, eliminate slack vagina, recover the physiological status that it is compact.
Claims (1)
1. women's cleansing gel suppository, is characterized in that: said women's cleansing gel suppository is made up of following component, with overall women's cleansing gel suppository quality be 100 grams (100% % by weight):
Aqueous phase substance is small-micelle water, and band width corresponding to the high point of 17 oxygen nuclear magnetic resonance, NMR amplitudes half is 45-80Hz, has 50 % by weight-70 % by weight;
Fat phase material be selected from olive oil, glycerol, vitamin E oil any one or a few, 20 % by weight-30 % by weight, wherein, vitamin E is fat-soluble, needs to be dissolved with oils and fats;
Epidermal cell repairing material is superoxide dismutase SOD and glutathion, and SOD is selected from Cu, Zn-SOD, and added SOD amount guarantees that every ml gel has 100-800u (enzyme is lived)/ml, glutathion 0.1-2mg/ml;
Moisture and crease-resistant material is kept to be hyaluronic acid, 0.1 % by weight-0.5 % by weight;
Non-ionic surface active agent adopt HLB value to be the sorbitan ester class of 10-18 and HLB value lower than 10 Sorbitan alcohols with the use of, 5 % by weight-8 % by weight;
Thickening agent is selected from polyacrylamide homo polymer or cellulose ether, 0.5% weight-1% weight;
Penetrating agent is propylene glycol, 2 % by weight-3 % by weight;
Antioxidant selects vitamin C, and with it the most at last pH of latex gel value adjust between 3.5-5.5;
Spice is selected from jasmin essence or Oleum Caryophylli, 0.0001 weight-0.001 % by weight.
Myrrha quintessence oil, 200-2000mg;
The material chlorogenic acid of eliminating bacteria and mycete, dihydromyricetin, resveratrol and nano oxidized Argent grain, can use 1-3 kind wherein,
Chlorogenic acid, 0-3000mg;
Dihydromyricetin, 0-3000mg;
Resveratrol, 0-300mg;
Nano oxidized Argent grain, 0 % by weight-0.01 % by weight;
When using nano oxidized Argent grain, dispersant diphosphonate ester need be added, 0.005 % by weight-0.01 % by weight;
In addition also have suitable moulding dose and other material, product can be made to become bullet shaped.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410745875.4A CN104623644A (en) | 2014-12-10 | 2014-12-10 | Gel suppository for cleaning of women |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410745875.4A CN104623644A (en) | 2014-12-10 | 2014-12-10 | Gel suppository for cleaning of women |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104623644A true CN104623644A (en) | 2015-05-20 |
Family
ID=53203199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410745875.4A Pending CN104623644A (en) | 2014-12-10 | 2014-12-10 | Gel suppository for cleaning of women |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104623644A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108403618A (en) * | 2018-04-26 | 2018-08-17 | 霍尔果斯汉智医药科技有限公司 | A kind of imiquimod vaginal expansion plug and preparation method thereof |
| WO2019028938A1 (en) * | 2017-08-08 | 2019-02-14 | 佛山科学技术学院 | Eugenol/clove oil suppository used for urethrae or anus and preparation method therefor |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370583A (en) * | 2010-08-16 | 2012-03-14 | 北京龙裔生物科技有限公司 | Cleaning emulsion for health of women |
-
2014
- 2014-12-10 CN CN201410745875.4A patent/CN104623644A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102370583A (en) * | 2010-08-16 | 2012-03-14 | 北京龙裔生物科技有限公司 | Cleaning emulsion for health of women |
Non-Patent Citations (7)
| Title |
|---|
| 唐传核: "《植物功能性食品》", 31 October 2004 * |
| 唐浩国等: "《黄酮类化合物研究》", 31 December 2008 * |
| 尹菊，刘立峰，周仲华: "谷胱甘肽、SOD软膏红外线照射治疗外阴营养不良的疗效分析", 《中国医科大学学报》 * |
| 李睿华等: "酸碱、硬度组成对水17O-NMR 化学位移和半峰宽的影响及与水缔合作用的关系", 《环境科学学报》 * |
| 沈红: "《几种药物对细胞体外分化成熟及功能影响的研究》", 31 July 2014 * |
| 管晶晶: "小分子团水真能保健治病吗", 《科技日报》 * |
| 维冈: "第四章 发现芳香植物的点滴", 《精油的益处》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019028938A1 (en) * | 2017-08-08 | 2019-02-14 | 佛山科学技术学院 | Eugenol/clove oil suppository used for urethrae or anus and preparation method therefor |
| CN108403618A (en) * | 2018-04-26 | 2018-08-17 | 霍尔果斯汉智医药科技有限公司 | A kind of imiquimod vaginal expansion plug and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP5065246B2 (en) | Compositions and methods for regulating and maintaining the microflora of straw and the acidity of straw | |
| KR102260231B1 (en) | Chloroquine gel and its preparation method, application | |
| EA026198B1 (en) | Multipurpose gel for vaginal dryness with direct and delayed effect | |
| CN106176430A (en) | A kind of disposable foam type women bactericidal liquid and preparation method thereof | |
| CN107456509B (en) | A kind of external application biological agent and preparation method for vagina prevention, health care and treatment gynaecology genital inflammation | |
| CN102908611A (en) | Bioprotein dressing and bioprotein invisible film for preventing and controlling human papilloma virus infection | |
| CN106109451A (en) | A kind of antibiotic preparation and preparation method thereof | |
| CN108158995A (en) | A kind of gynaecology's anti-bacteria foaming agent containing chitosan and preparation method thereof | |
| CN107952059A (en) | A kind of gynaecology's bacteriostatic gel and preparation method thereof | |
| CN105013001A (en) | Medical biological hydrogel function dressing for gynecology and preparation method of dressing | |
| CN106619780A (en) | Gynecological antibacterial gel | |
| CN104623644A (en) | Gel suppository for cleaning of women | |
| CN108553499A (en) | A kind of antibacterial conception control gel of the gynaecology of natural constituent and preparation method thereof | |
| CN110339249B (en) | Traditional Chinese medicine composition for treating hemorrhoids and anal fissure as well as preparation method and application thereof | |
| CN104288222A (en) | Nano-medicine for treating dairy cow endometritis and preparation method of nano-medicine | |
| JPH11511180A (en) | Physical disinfecting gel for cosmetics | |
| CN102416041A (en) | Antibacterial and anti-inflammatory Chinese medicinal composition and preparation method thereof | |
| CN113616774B (en) | Antibacterial composition containing plant stem cells, maintenance antibacterial liquid and preparation method thereof | |
| CN108938703A (en) | The gynecological gel of quick antibacterial | |
| CN102716408B (en) | Application of tsaoko amomum fruit to preparation of medicament for treating vaginitis | |
| CN113908206A (en) | Preparation method and application of gynecological antibacterial gel | |
| CN104623457B (en) | Vagina-shrinking expellent nti-freckle gelling agent and preparation method thereof | |
| CN103948661A (en) | Medicine combination for treating gynecological diseases, prostatic diseases or anorectal diseases, and application for same | |
| CN102462768A (en) | Female nursing solution for external use | |
| CN112999294A (en) | Soft gel and preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| DD01 | Delivery of document by public notice |
Addressee: Xu Zhaojing Document name: Notification of an Office Action |
|
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150520 |