CN104623548A - Traditional Chinese medicine composition for treating spontaneous perspiration disease - Google Patents

Traditional Chinese medicine composition for treating spontaneous perspiration disease Download PDF

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Publication number
CN104623548A
CN104623548A CN201510066460.9A CN201510066460A CN104623548A CN 104623548 A CN104623548 A CN 104623548A CN 201510066460 A CN201510066460 A CN 201510066460A CN 104623548 A CN104623548 A CN 104623548A
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chinese medicine
radix
medicine composition
traditional chinese
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CN104623548B (en
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孙向红
周业敏
赛丽娜
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Zhang Haiyan
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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and aims at providing a traditional Chinese medicine composition for treating a spontaneous perspiration disease according to the known mechanism of the spontaneous perspiration disease in the traditional Chinese medicine. The traditional Chinese medicine composition is characterized by being prepared from the following raw materials in parts by weight: 12-18 parts of rhizoma atractylodis macrocephalae, 9-15 parts of white peony root, 3-9 parts of liquorice, 25-35 parts of astragalus membranaceus, 9-12 parts of monkshood, 12-18 parts of polygonatum kingianum, 12-18 parts of angelica sinensis, 12-18 parts of curcuma aromatic, 25-35 parts of edestan, 12-18 parts of immature bitter orange, 9-15 parts of semen arecae, 25-35 parts of agrimonia pilosa ledeb, 9-15 parts of inula flower, 9-15 parts of cassia twig, 12-18 parts of mangnolia officinalis and 12-18 parts of aflatoxin. According to the traditional Chinese medicine composition, common medicines are selected as the medicines, but the common medicines are reasonably combined and are balanced in dosage by accurate dialectic analysis on the disease, so that a satisfactory therapeutic effect can be obtained.

Description

A kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration
Technical field
The invention belongs to technical field of Chinese medicines, specifically refer to a kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration.
Background technology
Disease of spontaneous perspiration belongs to hyperhidrosis category, general reference hyperhidrosis on daytime, and hyperhidrosis divides general hyperhidrosis and limitation hyperhidrosis, general hyperhidrosis and whole body sweating more, localized hyperhidrosis's many fingers health is a certain or position sweating amount in a few place is comparatively large, and a general trick hyperhidrosis is comparatively common.At present vitamin B1, oryzanol, diazepam etc. are adopted more to the treatment of hyperhidrosis, if sweating is a lot, suitably can take some anti-acetylcholine such as atropine or probanthine medicines, but, stable and anti-acetylcholine medicine has certain side effect, unsuitable long-term taking, therefore polygamy closes Chinese traditional treatment clinically.
Summary of the invention
The object of the invention is according to the traditional Chinese medical science to the understanding mechanism of disease of spontaneous perspiration one disease and then provide a kind of Chinese medicine composition for the treatment of this disease.
For realizing above-mentioned technical purpose, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 12-18 part, Radix Paeoniae Alba 9-15 part, Radix Glycyrrhizae 3-9 part, Radix Astragali 25-35 part, Radix Aconiti Lateralis Preparata 9-12 part, Rhizoma Polygonati 12-18 part, Radix Angelicae Sinensis 12-18 part, Radix Curcumae 12-18 part, Fructus Cannabis 25-35 part, Fructus Aurantii Immaturus 12-18 part, Semen Arecae 9-15 part, Herba Agrimoniae 25-35 part, Flos Inulae 9-15 part, Ramulus Cinnamomi 9-15 part, Cortex Magnoliae Officinalis 12-18 part, Massa Medicata Fermentata 12-18 part.
The optimum weight proportioning of above-mentioned raw materials medicine is: the Rhizoma Atractylodis Macrocephalae 15 parts, the Radix Paeoniae Alba 12 parts, 6 parts, Radix Glycyrrhizae, the Radix Astragali 30 parts, Radix Aconiti Lateralis Preparata 10 parts, Rhizoma Polygonati 15 parts, Radix Angelicae Sinensis 15 parts, Radix Curcumae 15 parts, Fructus Cannabis 30 parts, Fructus Aurantii Immaturus 15 parts, Semen Arecae 12 parts, Herba Agrimoniae 30 parts, Flos Inulae 12 parts, Ramulus Cinnamomi 12 parts, Cortex Magnoliae Officinalis 15 parts, Massa Medicata Fermentata 15 parts.
The instructions of taking of Chinese medicine composition provided by the present invention is: adopt the method for conventional fried Chinese medicine to get its medicine juice 300-500ml by after the mixing of the material medicine of above-mentioned weight proportion, every day takes for twice sooner or later, and every day one is secondary.
Prescription analysis: spontaneous perspiration one disease is disharmony of nutrient QI with defensive QI at all, nutrient QI belonging to blood, defensive QI belonging to vital QI, battalion defends and then key degree of having, and real be normal person, seeks and defends imbalance then or sweating, or aversion to cold aversion to wind.Sweating or for the deficiency of vital energy can not arresting sweating, or for exuberant lung-stomach heat causes retention and fumigation of damp-heat inside the body and cause.Based on above-mentioned cognition, in Chinese medicine composition provided by the present invention, mend the yang-energy of upper, middle and lower three Jiao with the Radix Astragali, Radix Aconiti Lateralis Preparata, Fructus Cannabis, Ramulus Cinnamomi, yang-energy must be mended, and antiperspirant is held back to some extent, to hold concurrently nourishing YIN liquid with the Radix Paeoniae Alba, Radix Angelicae Sinensis, anti-predominant yang impairing yin, negative and positive and then battalion defend with.Get the Rhizoma Atractylodis Macrocephalae simultaneously, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Massa Medicata Fermentata spleen invigorating regulate the flow of vital energy, more with the effect of Semen Arecae, Flos Inulae, Herba Agrimoniae, the Radix Curcumae therapeutic method to keep the adverse QI flowing downwards to fall hot and suffocating damp and hot of lung stomach.Above-mentioned all medicines share, and hot and suffocating so damp and hot that to fall of battalion's Wei get He, lung stomach, spontaneous perspiration one disease is from going.Although this Chinese medicine composition is common drug on choice of drug, by disease dialectical Analyses accurately, conventional medicine is carried out reasonable compatibility, consideration consumption, it can obtain gratifying therapeutic effect.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment 1
A kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 18g, Radix Paeoniae Alba 15g, Radix Glycyrrhizae 9g, Radix Astragali 35g, Radix Aconiti Lateralis Preparata 12g, Rhizoma Polygonati 18g, Radix Angelicae Sinensis 18g, Radix Curcumae 18g, Fructus Cannabis 35g, Fructus Aurantii Immaturus 18g, Semen Arecae 15g, Herba Agrimoniae 35g, Flos Inulae 15g, Ramulus Cinnamomi 15g, Cortex Magnoliae Officinalis 18g, Massa Medicata Fermentata 18g.
In the present embodiment, for carrying out toxicity test to medicine, the weight portion of each material medicine is got its maximum weight part and is tested, and toxicity test is divided into acute toxicity testing and long term toxicity test, and result is as follows:
Acute toxicity test: for convenience of carrying out dispensing feeding to white mice, the Chinese medicine decoction embodiment of the present invention 1 prepared carries out concentrated atomization pelletize and obtains Chinese medicinal granule.Chinese medicinal granule is dissolved in distilled water, with 195 of clinical consumption per day times to white mice dispensing feeding, observes 7.The activity of all white mice of result, diet, hair no abnormality seen, have no toxic reaction.Irritation test is carried out to white mouse oral cavity and damaged skin, there are no irritative response and other untoward reaction.
Long term toxicity test: the Chinese medicinal granule prepared in this embodiment of the invention is dissolved in water to mice by 20.15g crude drug/kg, to mice continuous use 16 weeks, every day 2 times, and drug withdrawal is after 2 weeks, result shows: the index such as hair, behavior, defecation, body weight, organ weights, hemogram, hepatic and renal function, blood glucose, blood fat of Chinese medicine of the present invention to test white mice all has no significant effect, and internal organs naked eyes do not find difference change.Employing histological indications shows, medication 16 weeks and drug withdrawal are after 2 weeks, and Organs of Mice is all without obviously changing.
Embodiment 2
A kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: the Rhizoma Atractylodis Macrocephalae 15, the Radix Paeoniae Alba 12, Radix Glycyrrhizae 6, the Radix Astragali 30, Radix Aconiti Lateralis Preparata 10, Rhizoma Polygonati 15, Radix Angelicae Sinensis 15, Radix Curcumae 15, Fructus Cannabis 30, Fructus Aurantii Immaturus 15, Semen Arecae 12, Herba Agrimoniae 30, Flos Inulae 12, Ramulus Cinnamomi 12, Cortex Magnoliae Officinalis 15, Massa Medicata Fermentata 15.
In the present embodiment, adopt the material medicine of above-mentioned weight proportion to carry out clinical trial, test as follows:
Spontaneous perspiration patient 86 example, wherein general spontaneous perspiration 32 example, limitation spontaneous perspiration 54 example, limitation spontaneous perspiration patient's sweating position focuses mostly in positions such as brothers, forehead, armpit, pudendum.
Treatment standard: sweating amount minimizing or effective, spontaneous perspiration disappears more than 4 weeks without recurring for healing.
Result is as follows:
Model case:
Female, 48 years old, irritated, emotional, the insomnia of emotion nearly half a year, headache, especially brothers' spontaneous perspiration, after feed, sweating amount strengthened a little, the visible brothers position globule, and the morning is slightly light, and aggravate in the afternoon.Time medical, observe its red complexion gorgeous, brothers are moistening, sausarism yellow fur, GUAN-pulse deep-thready pulse, the floating number of right chi.
Take Chinese medicine composition provided by the present invention after one week, reflection sweating amount obviously reduces, the morning is substantially without sweating, afternoon and after meal sweating slightly, simultaneously emotion has before comparing and taking medicine and more obviously improves, continue to take this Chinese medicine composition after 1 week, spontaneous perspiration symptom disappears completely, and 6 months so far again without recurrence.
Embodiment 3
A kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 12g, Radix Paeoniae Alba 15g, Radix Glycyrrhizae 3g, Radix Astragali 35g, Radix Aconiti Lateralis Preparata 9g, Rhizoma Polygonati 18g, Radix Angelicae Sinensis 12g, Radix Curcumae 18g, Fructus Cannabis 25g, Fructus Aurantii Immaturus 18g, Semen Arecae 9g, Herba Agrimoniae 35g, Flos Inulae 9g, Ramulus Cinnamomi 15g, Cortex Magnoliae Officinalis 12g, Massa Medicata Fermentata 18g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 18g, Radix Paeoniae Alba 9g, Radix Glycyrrhizae 9g, Radix Astragali 25g, Radix Aconiti Lateralis Preparata 12g, Rhizoma Polygonati 12g, Radix Angelicae Sinensis 18g, Radix Curcumae 12g, Fructus Cannabis 35g, Fructus Aurantii Immaturus 12g, Semen Arecae 15g, Herba Agrimoniae 25g, Flos Inulae 15g, Ramulus Cinnamomi 9g, Cortex Magnoliae Officinalis 18g, Massa Medicata Fermentata 12g.

Claims (2)

1. treat the Chinese medicine composition of disease of spontaneous perspiration for one kind, it is characterized in that, this Chinese medicine composition adopts the material medicine of following weight proportion to combine: Rhizoma Atractylodis Macrocephalae 12-18 part, Radix Paeoniae Alba 9-15 part, Radix Glycyrrhizae 3-9 part, Radix Astragali 25-35 part, Radix Aconiti Lateralis Preparata 9-12 part, Rhizoma Polygonati 12-18 part, Radix Angelicae Sinensis 12-18 part, Radix Curcumae 12-18 part, Fructus Cannabis 25-35 part, Fructus Aurantii Immaturus 12-18 part, Semen Arecae 9-15 part, Herba Agrimoniae 25-35 part, Flos Inulae 9-15 part, Ramulus Cinnamomi 9-15 part, Cortex Magnoliae Officinalis 12-18 part, Massa Medicata Fermentata 12-18 part.
2. a kind of Chinese medicine composition for the treatment of disease of spontaneous perspiration according to claim 1, it is characterized in that, the optimum weight proportioning of described material medicine is: the Rhizoma Atractylodis Macrocephalae 15 parts, the Radix Paeoniae Alba 12 parts, 6 parts, Radix Glycyrrhizae, the Radix Astragali 30 parts, Radix Aconiti Lateralis Preparata 10 parts, Rhizoma Polygonati 15 parts, Radix Angelicae Sinensis 15 parts, Radix Curcumae 15 parts, Fructus Cannabis 30 parts, Fructus Aurantii Immaturus 15 parts, Semen Arecae 12 parts, Herba Agrimoniae 30 parts, Flos Inulae 12 parts, Ramulus Cinnamomi 12 parts, Cortex Magnoliae Officinalis 15 parts, Massa Medicata Fermentata 15 parts.
CN201510066460.9A 2015-02-10 2015-02-10 A kind of Chinese medicine composition for treating disease of spontaneous perspiration Expired - Fee Related CN104623548B (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101053654A (en) * 2006-04-13 2007-10-17 董玺 Orally administered medicine in traditional Chinese medicine treating 'hyperhidrosis companied with warm-liking and cold-disgusting'

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101053654A (en) * 2006-04-13 2007-10-17 董玺 Orally administered medicine in traditional Chinese medicine treating 'hyperhidrosis companied with warm-liking and cold-disgusting'

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张钟爱: "《中医保健与养生》", 30 September 2009, 山西科学技术出版社 *
李古松: "话说自汗与盗汗", 《光明中医》 *

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Inventor after: Zhang Haiyan

Inventor after: Chi Chunmei

Inventor before: Sun Xianghong

Inventor before: Zhou Yemin

Inventor before: Sai Lina

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Effective date of registration: 20180209

Address after: The center of Shandong city of Qingdao province Jimo 266200 District No. 1281 LAN Ao Lu Jimo Hospital of traditional Chinese Medicine

Applicant after: Zhang Haiyan

Address before: 264300 Rongcheng City, Weihai Province, Shidao Management District, double the list of East Road, No. 199

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