CN104623255A - Spleen-invigorating and qi-supplementing preparation for treatment of enteritis and preparation method thereof - Google Patents
Spleen-invigorating and qi-supplementing preparation for treatment of enteritis and preparation method thereof Download PDFInfo
- Publication number
- CN104623255A CN104623255A CN201510088266.0A CN201510088266A CN104623255A CN 104623255 A CN104623255 A CN 104623255A CN 201510088266 A CN201510088266 A CN 201510088266A CN 104623255 A CN104623255 A CN 104623255A
- Authority
- CN
- China
- Prior art keywords
- parts
- preparation
- herba
- spleen
- invigorating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention discloses a spleen-invigorating and qi-supplementing preparation for treatment of enteritis, which is prepared from the following herbal materials in parts by weight: 8-15 parts of eucommia barks, 13-19 parts of panax notoginseng, 12-15 parts of field sowthistle herbs, 8-12 parts of radix paeoniae alba, 7-16 parts of herba polygalae japonicae, 6-12 parts of nutmeg, 9-15 parts of prunella vulgaris, 12-17 parts of leaves of shrubby baeckea, 7-15 parts of swertia yunnanensis, 12-19 parts of herba hyperici japonica, 9-16 parts of radix pseudostellariae, 5-12 parts of salix matsudana, 13-15 parts of lily, 6-16 parts of herba ecliptae, and 5-11 parts of fritillaria. The preparation has good effects of invigorating the spleen, supplementing qi, and regulating qi to alleviate pain, can fundamentally eliminate focuses, restore the liver function and enhance the immunity, and has a definite therapeutic effect, therefore, the preparation has a relatively high popularization value. The preparation disclosed by the invention is developed on the basis of Chinese medicine treatment based on syndrome differentiation and in combination with modern latest scientific research achievements, and through the combination application of various herbal materials, the preparation has the characteristics of distinct curative effect, safety, convenience, and low price.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of invigorating the spleen and benefiting QI preparation and preparation method for the treatment of enteritis.
Background technology
Along with raising and the living-pattern preservation of people's living standard, digestive tract disease is one of common clinical, sickness rate is in the trend risen year by year, the people that chronic gastrointestinal disease occurs in daily life accounts for about 30%, people's sickness rate of more than 40 years old is about 50%, is a large obstacle of human health.Enteritis is a kind of common digestive system disease, different by course of disease length, is divided into acute and chronic two classes.The chronic enteritis course of disease is longer, and the state of an illness is repeatedly touching, brings many worries to the live and work of people.Therefore, develop a kind of medicine for the treatment of enteritis safely and effectively and there is very important realistic meaning.
Enteritis belongs to the category such as " having loose bowels ", " watery diarrhea ", " dysentery " in motherland's medical science.Enteritis, polydipsia diseases caused by exogenous pathogenic factor six climate exopathogens, internal injury diet, prolongs to lose for a long time and controls.There are " wet contain, watery diarrhea ", the saying of " having loose bowels not from wet "." Jing Yue's complete work is had loose bowels " claims " having loose bowels originally, invariably by taste "." taste are injured, then water is anti-wet, and paddy is anti-stagnant, the gas of elite, can not defeatedization, cause and close dirty decline and let out profit and do ".The spleen has the function to transport and transform nutrients water paddy, spleen health movement then water paddy is taken their own roads, and damage of the spleen is transformation failure of spleen then, wet and be tending towards issuing as having loose bowels, have loose bowels with the passing of time, deficiency of spleen-QI declines, show as frequency of having loose bowels, soft stools, or press from both sides not digesting and absorbing the essence of foodstuff, shortness of breath and fatigue after an action of the bowels, pale white complexion, enlarged tongue, white and thin fur, deficient pulse, treatment should invigorating the spleen and benefiting QI be main.
Application publication number CN 104338093 A(application number 201310330968.6) Chinese invention patent document disclose a kind of Chinese medicine for the treatment of enteritis, be made up of the raw material of following weight proportion: Fructus Fici 5-15, Oletum Trogopterori 5-10, reed Ba Zi 3-10, Rhizoma Corydalis 10-15, Radix Aucklandiae 5-10, Endoconcha Sepiae 15-20, Semen Euryales 10-15, Pheretima 1-2, Rhizoma Zingiberis 15-30, Fructus Rosae Laevigatae 10-15, brown sugar 60-120.Application publication number CN 103860795 A(application number 201210527180.X) Chinese invention patent document disclose a kind of Chinese medicine for enteritis, it is made up of the raw material of following parts by weight: Rhizoma Coptidis 5-15, Radix Scutellariae 5-15, Semen Plantaginis 5-15, Fructus Crataegi 5-15, Poria 5-15, Rhizoma Pinelliae 5-15, Radix Puerariae 5-15, Radix Glycyrrhizae 5-15, the Rhizoma Atractylodis Macrocephalae 30, Rhizoma Atractylodis 5-15, Rhizoma Alismatis 5-15.Application publication number CN 104225511 A(application number 201310251251.2) Chinese invention patent document disclose a kind of Chinese medicine composition for the treatment of enteritis, be made up of the raw material of following weight proportion: Fructus Psoraleae 20 parts, reed Ba Zi 20 parts, Halloysitum Rubrum 30 parts, Semen Euryales 15 parts, Endoconcha Sepiae 15 parts, Galla Chinensis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, carbonized Rhizoma Zingiberis (processed) 15 parts, Radix Aucklandiae (roasted) 15 parts, Radix Pulsatillae l5 part, Oletum Trogopterori 15 parts, 15 parts, Flos Sophorae, Rhizoma Cimicifugae 15 parts, 15 parts, Semen Nelumbinis, 15 parts, Poria, Semen Arecae Preareta slice 15 parts, Rhizoma Corydalis 15 parts, Pericarpium Citri Reticulatae l5 part, Fructus Rosae Laevigatae 12 parts, Rhizoma Rhei charcoal 6 parts, RHIZOMA COPTIDIS from Sichuan of China 5 parts, fry 5 parts, foxtail millet shell, Cortex Cinnamomi 5 parts, Radix Notoginseng 5 parts.
Existing Western medicine is as medicine such as gentamycin sulfate and bismuth subcarbonate capsules, the norfloxacin etc. of antibiotic one class, and not only can not effect a radical cure, and easily develop immunity to drugs, side effect is large.The traditional Chinese medical science is taked dialectically to treat, the principle for the treatment of both the principal and secondary aspects of a disease, not only can eliminate focus, can also recover function, improve immunity of organisms, fundamentally cure diseases.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide and a kind ofly prepare simple, taking convenience, safely and effectively a kind of invigorating the spleen and benefiting QI preparation and preparation method for the treatment of enteritis.Invigorating the spleen and benefiting QI agent determined curative effect of the present invention is convenient to Clinical practice.
Technical scheme of the present invention is:
The invigorating the spleen and benefiting QI preparation for the treatment of enteritis, is prepared from by following bulk drugs, is weight portion: Cortex Eucommiae 8-15; Radix Notoginseng 13-19; Herba Sonchi Arvensis 12-15; Radix Paeoniae Alba 8-12; Herba Polygalae Japonicae 7-16; Semen Myristicae 6-12; Spica Prunellae 9-15; Folium Baeckeae 12-17; Gentiana rhodantha Franch. 7-15; Herba Hyperici Japonici 12-19; Radix Pseudostellariae 9-16; Dry land willow 5-12; Bulbus Lilii 13-15; Herba Ecliptae 6-16; Bulbus Fritillariae Cirrhosae 5-11.
In preferred scheme, Cortex Eucommiae 10-13; Radix Notoginseng 15-17; Herba Sonchi Arvensis 13-14; Radix Paeoniae Alba 9-11; Herba Polygalae Japonicae 10-13; Semen Myristicae 8-10; Spica Prunellae 11-13; Folium Baeckeae 13-16; Gentiana rhodantha Franch. 10-12; Herba Hyperici Japonici 14-17; Radix Pseudostellariae 12-13; Dry land willow 7-10; Bulbus Lilii 13.5-14.5; Herba Ecliptae 8-14; Bulbus Fritillariae Cirrhosae 7-9.
Be more preferably, the Cortex Eucommiae 11.5; Radix Notoginseng 16; Herba Sonchi Arvensis 13.5; The Radix Paeoniae Alba 10; Herba Polygalae Japonicae 11.5; Semen Myristicae 9; Spica Prunellae 12; Folium Baeckeae 14.5; Gentiana rhodantha Franch. 11; Herba Hyperici Japonici 15.5; Radix Pseudostellariae 12.5; Dry land willow 8.5; Bulbus Lilii 14; Herba Ecliptae 11; Bulbus Fritillariae Cirrhosae 8.
The invigorating the spleen and benefiting QI preparation for the treatment of enteritis, be made into pharmaceutically acceptable pill, preparation method is as follows:
(1) Bulbus Fritillariae Cirrhosae is cleaned, and removes the heart, is used as medicine in pot, and slow fire is fried to surface yellowish, drenches into Sucus Zingberis, continues to stir-fry to being buff, and taking-up cools, and pulverizes for subsequent use; Gentiana rhodantha Franch. sheet is placed in medicine pot, and moderate heat cures 6-10 minute (preferred slow fire cures 8 minutes), takes out, pulverizes for subsequent use;
(2) Semen Myristicae is cleaned, and is placed in the Fructus Jujubae of enucleation one by one, drops in the sand made popular, suitably stirs, and takes out, peel off Fructus Jujubae shell, smash to pieces when turning black to Fructus Corni, for subsequent use;
(3) Cortex Eucommiae, Radix Notoginseng, the Radix Paeoniae Alba and Radix Pseudostellariae are together placed in Chinese medicine grinder, are ground into fine powder, gained fine powder is mixed with step (1) and step (2) gained fine powder, sieves for subsequent use;
(4) Herba Sonchi Arvensis, Herba Polygalae Japonicae, Spica Prunellae, Folium Baeckeae, Herba Hyperici Japonici, dry land willow, Bulbus Lilii and Herba Ecliptae are adopted water extraction, adding clear water did not have powder to soak, then slow fire boiling twice, each respectively decoction 35-55 minute (preferably each each decoction 45 minutes), filter, collecting decoction; Medicinal residues add the ethanol extraction (preferably adding the ethanol extraction of 4 times amount) of 3-5 times amount, heating and refluxing extraction 20-30 minute (preferred heating and refluxing extraction 25 minutes), filter, collect filtrate, reclaim ethanol, merge with above-mentioned decocting liquid, continuing to be evaporated to 65 DEG C of relative densities is the thick paste of 1.10-1.13, for subsequent use;
(5) join in above-mentioned thick paste by step (3) gained mixing fine powders, add cane sugar powder and Fructus Crataegi powder simultaneously, mixing, is processed into the pill of Semen Firmianae size, obtains final product.
The preparation method of the invigorating the spleen and benefiting QI pill of above-mentioned treatment enteritis, preferred scheme is, the middle 90-130 mesh sieve excessively of step (3) (preferred 100-120 mesh sieve excessively, mistake 110 mesh sieve be more preferably).
The preparation method of the invigorating the spleen and benefiting QI pill of above-mentioned treatment enteritis, preferred scheme is, the time of soaking in step (4) is 1.5-3.5 hour (the preferred time of soaking is 2-3 hour, and the time of the immersion be more preferably is 2.5 hours).
The preparation method of the invigorating the spleen and benefiting QI pill of above-mentioned treatment enteritis, preferred scheme is, in step (4), the mass concentration of added ethanol is the mass concentration of the preferred added ethanol of 65%-85%(is 70%-80%, and the mass concentration of the added ethanol be more preferably is 75%).
The preparation method of described decoction is:
(1) put in medicine pot by Semen Myristicae and Testa Tritici, slow fire heats, and stir-frying to Testa Tritici is coke yellow, when Semen Myristicae is dark-brown, takes out, removes Testa Tritici, smash to pieces for subsequent use; Get Fructus Schisandrae Chinensis and add water-wet, steam to bronzing, mix thoroughly (Fructus Schisandrae Chinensis: Mel=5:2) with Mel, reenter in steamer and steam to black for spending, taking-up cools, and smashs to pieces for subsequent use;
(2) get Cortex Eucommiae silk, add Chinese liquor and mix thoroughly, slightly moisten, be used as medicine in pot, moderate heat is fried to fracture of wire, surface coke black, takes out, cools completely, grind into powder for subsequent use;
(3) medical material step (1) and step (2) processed and surplus stock medicine are together placed in Chinese medicinal pot, add the pure water (preferably adding the pure water of 9 times amount) of 7-11 times amount, medicinal cupping is placed on stove fire, intense fire is heated to boil, turn slow fire boiling twice, first time decocts 1-1.5 hour (preferably first time decocts 1.3 hours), and second time decocts 35-45 minute (preferably second time decocts 40 minutes), filter, merge twice decocting liquid;
(4) above-mentioned decocting liquid is continued be concentrated into original volume 1/2,101 DEG C of dry heat sterilization 20-30 minute (preferably 101 DEG C dry heat sterilization 25 minutes), encapsulation, to obtain final product.
The preparation method of described granule is:
(1) take various crude drug by formula proportion, first clean, dry, then grind into powder, cross 100-140 mesh sieve (preferred mistake 120 mesh sieve), obtain mixed powder;
(2) in above-mentioned medicated powder, add sucrose fine and sodium cellulosate (medicated powder: sucrose fine: sodium cellulosate=4:1.3:1.1), do wetting agent, be placed in granulator and be processed into granule with the ethanol of 70%, cross No. four sieves, granulate, subpackage, to obtain final product.
The preparation method of described tablet is:
(1) take various crude drug by formula proportion, first clean, dry, then grind into powder, cross 80-120 mesh sieve (preferred mistake 100 mesh sieve), obtain mixed powder;
(2) above-mentioned medicated powder is measured according to 0.3-0.5g/ sheet (preferably according to 0.4g/ sheet), make tablet dosage form according to the preparation for processing of tablet.
Scientific formula of the present invention, preparation method is simple, easy to use, Be very effective.In addition, excellent results of the present invention also shows:
1,the present invention uses theory of Chinese medical science to analyze prescription composition, and according to each physicochemical property of flavour of a drug ingredient and the result of study of pharmacological action, research obtains the preparation method of reasonable, stable active component;
2,medicine of the present invention has the effect of invigorating the spleen and benefiting QI, regulating QI to relieve pain, fundamentally can eliminate focus, recovers liver function, and improve immunity, determined curative effect, has higher promotional value.
3,medicine of the present invention develops in conjunction with latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment, and all medicines share, and has evident in efficacy, safe ready, cheap feature.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the invigorating the spleen and benefiting QI preparation for the treatment of enteritis, is prepared from by following bulk drugs, is weight portion (45g/ part): the Cortex Eucommiae 8 parts; Radix Notoginseng 13 parts; Herba Sonchi Arvensis 12 parts; The Radix Paeoniae Alba 8 parts; Herba Polygalae Japonicae 7 parts; Semen Myristicae 6 parts; Spica Prunellae 9 parts; Folium Baeckeae 12 parts; Gentiana rhodantha Franch. 7 parts; Herba Hyperici Japonici 12 parts; Radix Pseudostellariae 9 parts; Dry land willow 5 parts; Bulbus Lilii 13 parts; Herba Ecliptae 6 parts; Bulbus Fritillariae Cirrhosae 5 parts.
The preparation method of the invigorating the spleen and benefiting QI pill of above-mentioned treatment enteritis is:
(1) Bulbus Fritillariae Cirrhosae is cleaned, and removes the heart, is used as medicine in pot, and slow fire is fried to surface yellowish, drenches into Sucus Zingberis, continues to stir-fry to being buff, and taking-up cools, and pulverizes for subsequent use; Gentiana rhodantha Franch. sheet is placed in medicine pot, and moderate heat cures 6 minutes, takes out, pulverizes for subsequent use;
(2) Semen Myristicae is cleaned, and is placed in the Fructus Jujubae of enucleation one by one, drops in the sand made popular, suitably stirs, and takes out, peel off Fructus Jujubae shell, smash to pieces when turning black to Fructus Corni, for subsequent use;
(3) Cortex Eucommiae, Radix Notoginseng, the Radix Paeoniae Alba and Radix Pseudostellariae are together placed in Chinese medicine grinder, are ground into fine powder, gained fine powder is mixed with step (1) and step (2) gained fine powder, cross 90 mesh sieves, for subsequent use;
(4) Herba Sonchi Arvensis, Herba Polygalae Japonicae, Spica Prunellae, Folium Baeckeae, Herba Hyperici Japonici, dry land willow, Bulbus Lilii and Herba Ecliptae are adopted water extraction, add clear water and do not have powder to soak 1.5 hours, then slow fire boiling twice, each each decoction 35 minutes, filters, collecting decoction; Medicinal residues add 3 times amount, mass concentration is the ethanol extraction of 65%, heating and refluxing extraction 20 minutes, filter, and collect filtrate, and reclaim ethanol, merge with above-mentioned decocting liquid, continuing to be evaporated to 65 DEG C of relative densities is the thick paste of 1.10-1.13, for subsequent use;
(5) join in above-mentioned thick paste by step (3) gained mixing fine powders, add cane sugar powder and Fructus Crataegi powder simultaneously, mixing, is processed into the pill of Semen Firmianae size, obtains final product.
The instructions of taking of pill of the present invention is: every day three times, each 8 balls, and warm water takes, 7 days courses for the treatment of.
Model case: Zhu XX, man, 43 years old, people from Tai'an.Because eating and drinking without temperance brings out lower abdomen dull pain before patient half a year, the alternately outbreak of constipation diarrhoea, to county hospital, give transfusion and Chinese medicine for oral administration treatment, symptom takes a turn for the better to some extent, but is easily interrupted outbreak.After being introduced, on October 14th, 2011, my institute's inspection was treated.Check: put down soft through patient's abdominal part, have tenderness liver around umbilicus, hepatic portal falling inflation, dysporia, anorexia, weak, body of the tongue is light red, white and thin fur, thready and stringy pulse.Electronic colonoscope examination, prompts for proctitis.
Take the invigorating the spleen and benefiting QI pill of the present embodiment gained treatment enteritis, instructions of taking: every day three times, each 8 balls, warm water takes, 7 days courses for the treatment of.After the course for the treatment of of medication, patient suffers from abdominal pain disappearance, and other sings and symptomses obviously alleviate, and after continuing two courses for the treatment of of medication, check that patients symptomatic and sign all disappear, patient fully recovers.Advise regular diet, note work and rest.
embodiment 2the invigorating the spleen and benefiting QI preparation for the treatment of enteritis, is prepared from by following bulk drugs, is weight portion (25g/ part): the Cortex Eucommiae 15 parts; Radix Notoginseng 19 parts; Herba Sonchi Arvensis 15 parts; The Radix Paeoniae Alba 12 parts; Herba Polygalae Japonicae 16 parts; Semen Myristicae 12 parts; Spica Prunellae 15 parts; Folium Baeckeae 17 parts; Gentiana rhodantha Franch. 15 parts; Herba Hyperici Japonici 19 parts; Radix Pseudostellariae 16 parts; Dry land willow 12 parts; Bulbus Lilii 15 parts; Herba Ecliptae 16 parts; Bulbus Fritillariae Cirrhosae 11 parts.
The preparation method of the invigorating the spleen and benefiting QI decoction of above-mentioned treatment enteritis is:
(1) put in medicine pot by Semen Myristicae and Testa Tritici, slow fire heats, and stir-frying to Testa Tritici is coke yellow, when Semen Myristicae is dark-brown, takes out, removes Testa Tritici, smash to pieces for subsequent use; Get Fructus Schisandrae Chinensis and add water-wet, steam to bronzing, mix thoroughly (Fructus Schisandrae Chinensis: Mel=5:2) with Mel, reenter in steamer and steam to black for spending, taking-up cools, and smashs to pieces for subsequent use;
(2) get Cortex Eucommiae silk, add Chinese liquor and mix thoroughly, slightly moisten, be used as medicine in pot, moderate heat is fried to fracture of wire, surface coke black, takes out, cools completely, grind into powder for subsequent use;
(3) medical material step (1) and step (2) processed and surplus stock medicine are together placed in Chinese medicinal pot, add the pure water of 9 times amount, medicinal cupping is placed on stove fire, intense fire is heated to boil, turn slow fire boiling twice, first time decocts 1.3 hours, and second time decocts 40 minutes, filter, merge twice decocting liquid;
(4) above-mentioned decocting liquid is continued be concentrated into original volume 1/2,101 DEG C of dry heat sterilizations 25 minutes, encapsulation, to obtain final product.
The instructions of taking of decoction of the present invention is: twice daily, each 120-150mL, warmly takes, 7 days courses for the treatment of.
Model case: model XX, female, 29 years old, people from Jiaxiang, Jining.Patient because of stomachache, diarrhoea 3 days to our hospital in December in 2011 3 days.Check: there is obvious tenderness patient's umbilicus center, without radiating pain, with nausea.After detailed understanding, learn that patient belongs to Acute onset, have unclean dietary history, to suffer from abdominal pain, to suffer from diarrhoea with vomiting as cardinal symptom.Routine blood test: WBC:17.8 × 10
9/ L, N 83.9%.Just conventional: WBC:8-10/HPF, is diagnosed as acute enteritis clear and definite.
Take the invigorating the spleen and benefiting QI decoction of the present embodiment gained treatment enteritis, instructions of taking: twice daily, each 120-150mL, warmly takes, 7 days courses for the treatment of.After treating a course for the treatment of, patient's stomachache, diarrhoea disappear, and continual cure is consolidated a course for the treatment of, and patient fully recovers, and follows up a case by regular visits to after three months, and patient body is healthy, without recurrence.
embodiment 3the invigorating the spleen and benefiting QI preparation for the treatment of enteritis, is prepared from by following bulk drugs, is weight portion (40g/ part): the Cortex Eucommiae 10 parts; Radix Notoginseng 15 parts; Herba Sonchi Arvensis 13 parts; The Radix Paeoniae Alba 9 parts; Herba Polygalae Japonicae 10 parts; Semen Myristicae 8 parts; Spica Prunellae 11 parts; Folium Baeckeae 13 parts; Gentiana rhodantha Franch. 10 parts; Herba Hyperici Japonici 14 parts; Radix Pseudostellariae 12 parts; Dry land willow 7 parts; Bulbus Lilii 13.5 parts; Herba Ecliptae 8 parts; Bulbus Fritillariae Cirrhosae 7 parts.
The preparation method of the invigorating the spleen and benefiting QI granule of above-mentioned treatment enteritis is:
(1) take various crude drug by formula proportion, first clean, dry, then grind into powder, cross 120 mesh sieves, obtain mixed powder;
(2) in above-mentioned medicated powder, add sucrose fine and sodium cellulosate (medicated powder: sucrose fine: sodium cellulosate=4:1.3:1.1), do wetting agent, be placed in granulator and be processed into granule with the ethanol of 70%, cross No. four sieves, granulate, subpackage, to obtain final product.
The instructions of taking of granule of the present invention is: every day three times, each 20-25g, and warm water is taken after mixing it with water, 7 days courses for the treatment of.
Model case: Lee XX, man, 53 years old, people from Heze.Patient is to our hospital on April 2nd, 2012.Check: patient has a surplus for 3 years.Symptoms is: patient's weak breath is weak, is reluctant speech; Diet can; Feeling of fullness in the head, dizzy; Insomnia, dreaminess; Umbilicus week pain, left lower abdominal pain is obvious, separates mucus band blood stool and indigestible food debris every day, about 4-6 time, and with rectal tenesmus, tenesmus sense, yellowish complexion of becoming thin, speaks unable, and the few and indigestion of diet, looks into through intestinal mirror and be diagnosed as chronic colitis.
Take the invigorating the spleen and benefiting QI granule of the present embodiment gained treatment enteritis, instructions of taking: every day three times, each 20-25g, warm water is taken after mixing it with water, 7 days courses for the treatment of.After the course for the treatment of of medication, patient suffers from abdominal pain disappearance, and other sings and symptomses obviously alleviate, and after continuing two courses for the treatment of of medication, check that patients symptomatic and sign all disappear, patient fully recovers.Advise regular diet, note work and rest.
embodiment 4the invigorating the spleen and benefiting QI preparation for the treatment of enteritis, is prepared from by following bulk drugs, is weight portion (30g/ part): the Cortex Eucommiae 13 parts; Radix Notoginseng 17 parts; Herba Sonchi Arvensis 14 parts; The Radix Paeoniae Alba 11 parts; Herba Polygalae Japonicae 13 parts; Semen Myristicae 10 parts; Spica Prunellae 13 parts; Folium Baeckeae 16 parts; Gentiana rhodantha Franch. 12 parts; Herba Hyperici Japonici 17 parts; Radix Pseudostellariae 13 parts; Dry land willow 10 parts; Bulbus Lilii 14.5 parts; Herba Ecliptae 14 parts; Bulbus Fritillariae Cirrhosae 9 parts.
The preparation method of the invigorating the spleen and benefiting QI tablet of above-mentioned treatment enteritis is:
(1) take various crude drug by formula proportion, first clean, dry, then grind into powder, cross 100 mesh sieves, obtain mixed powder;
(2) above-mentioned medicated powder is measured according to 0.4g/ sheet, make tablet dosage form according to the preparation for processing of tablet.
The instructions of taking of Tablets is: every day three times, each 5-7 sheet, and warm water is taken after mixing it with water, 7 days courses for the treatment of.
Model case: Lee XX, man, 43 years old, people from Tianjin.Patient's readme is certain business unit manager, and because long-term overtime work is stayed up late, count on young and vigorous, diet raw food is not avoided.Started before 2 years, stomachache, diarrhoea companion bloody purulent stool, mucus are just.Once be diagnosed as enteritis at a general hospital, use a lot of anti-inflammation drugs, but DeGrain, recurrence at once after drug withdrawal.Afterwards upon somebody's introduction, have the attitude of having a try in arms, Lee is first born on July 13rd, 2012 and carrys out my institute's inspection treatment.Check: patient's left lower abdominal pain, diarrhoea companion bloody purulent stool, afterwards through electronic colonoscope examination, was finally diagnosed as chronic enteritis.
Take the invigorating the spleen and benefiting QI tablet of the present embodiment gained treatment enteritis, instructions of taking: every day three times, each 5-7 sheet, warm water is taken after mixing it with water, 7 days courses for the treatment of.After two courses for the treatment of of medication, all diseases of patient subtract greatly, shaping of defecating, and only have back segment slightly rare.Patient is full of confidence, continues medication and is consolidated 2 courses for the treatment of, do microscopy again after treatment, and result display affected part is without petechia, and ulcer healing, patient fully recovers.
embodiment 5the invigorating the spleen and benefiting QI preparation for the treatment of enteritis, is prepared from by following bulk drugs, is weight portion (35g/ part): the Cortex Eucommiae 11.5 parts; Radix Notoginseng 16 parts; Herba Sonchi Arvensis 13.5 parts; The Radix Paeoniae Alba 10 parts; Herba Polygalae Japonicae 11.5 parts; Semen Myristicae 9 parts; Spica Prunellae 12 parts; Folium Baeckeae 14.5 parts; Gentiana rhodantha Franch. 11 parts; Herba Hyperici Japonici 15.5 parts; Radix Pseudostellariae 12.5 parts; Dry land willow 8.5 parts; Bulbus Lilii 14 parts; Herba Ecliptae 11 parts; Bulbus Fritillariae Cirrhosae 8 parts.
The preparation method of the invigorating the spleen and benefiting QI pill of above-mentioned treatment enteritis is:
(1) Bulbus Fritillariae Cirrhosae is cleaned, and removes the heart, is used as medicine in pot, and slow fire is fried to surface yellowish, drenches into Sucus Zingberis, continues to stir-fry to being buff, and taking-up cools, and pulverizes for subsequent use; Gentiana rhodantha Franch. sheet is placed in medicine pot, and moderate heat cures 8 minutes, takes out, pulverizes for subsequent use;
(2) Semen Myristicae is cleaned, and is placed in the Fructus Jujubae of enucleation one by one, drops in the sand made popular, suitably stirs, and takes out, peel off Fructus Jujubae shell, smash to pieces when turning black to Fructus Corni, for subsequent use;
(3) Cortex Eucommiae, Radix Notoginseng, the Radix Paeoniae Alba and Radix Pseudostellariae are together placed in Chinese medicine grinder, are ground into fine powder, gained fine powder is mixed with step (1) and step (2) gained fine powder, sieves for subsequent use;
(4) Herba Sonchi Arvensis, Herba Polygalae Japonicae, Spica Prunellae, Folium Baeckeae, Herba Hyperici Japonici, dry land willow, Bulbus Lilii and Herba Ecliptae are adopted water extraction, add clear water and do not have powder to soak, then slow fire boiling twice, each each decoction 45 minutes, filters, collecting decoction; Medicinal residues add the ethanol extraction of 4 times amount, heating and refluxing extraction 25 minutes, filter, and collect filtrate, and reclaim ethanol, merge with above-mentioned decocting liquid, continuing to be evaporated to 65 DEG C of relative densities is the thick paste of 1.10-1.13, for subsequent use;
(5) join in above-mentioned thick paste by step (3) gained mixing fine powders, add cane sugar powder and Fructus Crataegi powder simultaneously, mixing, is processed into the pill of Semen Firmianae size, obtains final product.
The instructions of taking of pill of the present invention is: every day three times, each 8 balls, and warm water takes, 7 days courses for the treatment of.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The Cortex Eucommiae: base is former: this product is the dry bark of the Eucommiaceae plant Cortex Eucommiae.Character: this product be en plaque or both sides slightly toward curls inward, not of uniform size, thick 3-7mm.Outer surface light brown or taupe, have obvious wrinkle or lobe groove stricture of vagina, some barks are thinner, do not remove rough bark, visible significantly hole skin.Inner surface mulberry, smooth.Matter is crisp, frangibility, and section has fine and closely woven, silvery white, rubber thread full of elasticity to be connected.Feeble QI, taste is slightly bitter.Nature and flavor: sweet, temperature.Gui Jing: return liver, kidney channel.Effect: invigorating the liver and kidney, bone and muscle strengthening.Antiabortive.Curing mainly: for lumbago due to renal deficiency. muscles and bones is unable, blood leaking in gestation, frequent fetal movement; Hypertension.
Radix Notoginseng: base is former: this product is the dry root and rhizome of panax araliaceae plant.Nature and flavor: sweet, micro-hardship, temperature.Gui Jing: return liver, stomach warp.Effect: dissipating blood stasis stops blooding, subduing swelling and relieving pain.Cure mainly: for spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Herba Sonchi Arvensis: base is former: be the herb of feverfew Herba Sonchi Arvensis.Pharmacological action: antitumor action.Herba Sonchi Arvensis water boiling concentration alcoholic extract has obvious inhibitory action to acute lymphoblastic type leukemia, acute and chronic myelocytic leukemia patient hemocyte dehydrogenase.Nature and flavor: " Hebei Chinese medicine handbook ": " cold in nature, bitter in the mouth." function cures mainly: heat-clearing and toxic substances removing, tonify deficiency cough-relieving.Control bacillary dysentery, laryngitis, weak cough, internal hemorrhoid is deviate from, leucorrhea.
The Radix Paeoniae Alba: base is former: this product is the dry root of ranunculaceae plant Radix Paeoniae.Chemical analysis: root contains paeoniflorin, paeonol, paeoniflorin, benzoic acid about 1.07%, volatile oil, fatty oil, resin, tannin, sugar, starch, phlegmatic temperament, protein, cupreol and triterpenes.Nature and flavor: bitter, sour, are slightly cold.Gui Jing: return liver, spleen channel.Effect: suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Cure mainly: dizzy for having a headache, hypochondriac pain, stomachache, limb pain twin, blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat.
Herba Polygalae Japonicae: base is former: be herb or the root of milk wort Herba Polygalae Japonicae.Chemical analysis: root is containing triterpenoid saponin, resin, fatty oil, polygalytol.Nature and flavor: arduous are flat.Function cures mainly: antitussive, reduces phlegm, and invigorates blood circulation, and hemostasis, calms the nerves, removing toxic substances.Control cough with copious phlegm, spit blood, have blood in stool, palpitation with a distress feeling, insomnia, laryngopharynx swelling and pain, skin sore, venom, traumatic injury.
Semen Myristicae: base is former: be the myristic seed of myristicaceae plant.Chemical analysis: containing volatile oil 2 ~ 9%, comprises d-camphene and australene etc.In its fat, content of myristic acid reaches 70 ~ 80%, and containing noxious substance myristicin.Pharmacological action: Semen Myristicae oil, apart from outside armaticity, still has the anesthesia performance shown.Nature and flavor: pungent, temperature.Gui Jing: enter lung, large intestine channel.Function cures mainly: warming middle-JIAO, and the therapeutic method to keep the adverse QI flowing downwards helps digestion, Gu intestinal.Control trusted subordinate's distending pain, diarrhea of deficiency type cold-dysentery, vomiting, dyspepsia does not disappear.
Spica Prunellae: base is former: this product is the dry fruit ear of labiate Spica Prunellae.Chemical analysis: herb is containing triterpenoid saponin, its glycoside unit is oleanolic acid, still containing free oleanolic acid, ursolic acid, globulariacitrin, hyperin, cis-caffeic acid, trans-caffeic acid, vitamin B1, vitamin C, vitamin K, carotene, resin, amaroid, tannin, volatile oil, alkaloid, water soluble salt (about 3.5%, wherein about 63% is potassium chloride) etc.Nature and flavor: pungent, bitter, cold.Gui Jing: return liver, gallbladder meridian.Pharmacological action: 1. hypotensive effect, 2. antibacterial action.Effect: relieve inflammation or internal heat, improving eyesight, eliminating stagnation, detumescence.Cure mainly: for conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, and acute mastitis swells and ache; Thyromegaly, tuberculous lymphadenitis, cyclomastopathy, hypertension.
Folium Baeckeae: base is former: be herb or the root of myrtle Folium Baeckeae.Chemical analysis: leaf is containing volatile oil 0.9～1。8%, wherein australene and nopinene account for 58%, to P-cymene 0.7%, 1, 8-Cineole 7.4%, limonene and cinene totally 3.1%, linalool, fenchol, Borneolum Syntheticum and terpineol totally 10%, sesquiterpene 1.4%, sesquiterpene alcohols 3%, phenols 2.4%, the 2, 2-Oxydiphenol 5 of crystallization.5％。In addition, also containing baeckeol.Nature and flavor: " Nanning City's medicine will ": " bitter, cold, nontoxic." function cures mainly: blood stasis removing, pain relieving, diuresis, parasite killing.Control traumatic injury, rheumatalgia, gonorrhea, scabies, tinea pedis.
Gentiana rhodantha Franch.: base is former: be root and the herb of gentianaceae plant red Radix Gentianae.Chemical analysis: herb contains positive hentriacontane, n-dotriacontane acetoacetic ester, n-dotriacontane acid, cupreol; Another containing swertiamarin, kingiside, sweroside, 8-epikingiside, red Radix Gentianae kind glycoside, oleanolic acid.Nature and flavor: bitter; Cold in nature; Gui Jing: the heart; Lung; Stomach; Large intestine channel; Function cures mainly: clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body.Main lung-heat cough with asthma; Consumptive disease is coughed expectorant blood; Jaundice; Dysentery; Have blood in stool; Dysuria; Lochiopyra; Infantile convulsion; Infantile malnutrition; Sore swollen toxin; Burn and scald; Venom.
Herba Hyperici Japonici: base is former: be the herb of Garcinia maingayii Herba Hyperici Japonici.Nature and flavor: sweet; Bitter; Cool.Gui Jing: lung; Liver; Stomach warp.Function cures mainly: clearing away heat-damp and promoting diuresis; Removing toxic substances; Dissipating blood stasis for subsidence of swelling.Main jaundice due to damp-heat; Have loose bowels; Dysentery; Intestinal carbuncle; Carbuncle furuncle and phyma poison; Tonsillitis; Aphtha; Conjunctival congestion and swelling pain; Venom; Traumatic injury
Radix Pseudostellariae: base is former: be the tuber of pinkwort pseudostellaria heterophylla.Chemical analysis: root is containing fructose, starch, Saponin.Nature and flavor: sweetness and bitterness, tepor.Gui Jing: " book on Chinese herbal medicine is new again ": " enter the heart, spleen, lung three warp." function cures mainly: tonifying the lung, strong board.Control cough due to deficiency of the lung, insufficiency of the spleen lack of appetite, cardiopalmus spontaneous perspiration, metal fatigue.Replenishing QI to invigorate the spleen, promoting the production of body fluid for nourishing the lung.For insufficiency of the spleen weak, after being ill thirsty, the lung of weakness, deficiency of both vital energy and Yin, spontaneous perspiration to make an uproar dry cough.
Dry land willow: base is former: the tender leaf of Salicaceae sallow dry land willow, branch or bark.The property of medicine: bitter, cold.Function cures mainly: removing damp-heat, reducing swelling and alleviating pain.Cure mainly acute cystitis, dysuria, arthritis, impetigo, sore, toothache.
Bulbus Lilii: base is former: be liliaceous plant Bulbus Lilii, Lilium tenuifolium, Lilium longiflorum and the scale leaf belonging to various plants bulb together thereof.Chemical analysis: lily bulb is containing multiple alkaloid and starch, protein, fat etc. such as colchicine.Pharmacological action: Bulbus Lilii decoct has antitussive action to the mouse cough that ammonia causes, white mice lung perfusion makes flow increase, and the Bufo siccus asthma that can cause antihistaminic.Nature and flavor: sweet micro-hardship are flat.Gui Jing: enter the heart, lung meridian.Function cures mainly: nourishing the lung to arrest cough, clearing away heart-fire for tranquillization.Control lung expense chronic cough, cough and spit expectorant blood; After calentura, waste heat comes clear, and fidgets due to deficiency is palpitated with fear, staring spells; Beriberi edema.(1) nourishing the lung to arrest cough: for cough, the spitting of blood of the dryness of the lung or the deficiency of YIN, often join Bulbus Fritillariae Cirrhosae.(2) clearing away heart-fire for tranquillization:, restlessness of asrhenia type and insomnia, staring spells unclear for waste heat after febrile disease, often joins Radix Rehmanniae.
Herba Ecliptae: base is former: this product is the dry aerial parts of feverfew Eclipta prostrata.Nature and flavor: sweet, sour, cold.Gui Jing: return kidney, Liver Channel.Effect: nourishing liver, kidney, cooling blood for hemostasis.Cure mainly: for odontoseisis, early whitening of beard and hair, vertigo and tinnitus, soreness of the waist and knees, YinXuXueRe, haematemesis, epistaxis, hematuria, dysentery, metrostaxis, traumatic hemorrhage.Cure mainly: nourishing the liver and kidney, cooling blood for hemostasis, various haematemesis can be controlled, the diseases such as enterorrhagia.Smash juice painting eyebrow to send out, can promote hair growth, for oral administration have black hair, hair color effect.
Bulbus Fritillariae Cirrhosae: base is former: be the bulb of liliaceous plant Fritillaria Cirrhosa D. Don, crow flower Bulbus Fritillariae Uninbracteatae or rib sand Bulbus Fritillariae Uninbracteatae etc.Nature and flavor: bitter sweet, cool.Gui Jing: enter lung meridian.Function cures mainly: lung moistening eliminating stagnation, antitussive reduces phlegm.Control cough due to consumptive disease, spitting of blood of spitting, ambition pent-up, consumptive lung disease, lung abscess, goiter, honest and clean scrofula, sore throat, acute mastitis.
test example 1a kind of clinical practice for the treatment of the invigorating the spleen and benefiting QI preparation (embodiment 5) of enteritis of gained of the present invention:
1 data and method
1.1 physical data
Choose enteritis patient 319 that in November ,-2013 in July, 2010, my institute accepted for medical treatment example, wherein male 166 example, women 153 example, age 27-55 year, 35.5 ± 4.5 years old mean age.All patients all meet enteritis diagnostic criteria, and make a definite diagnosis through enteroscopy.
1.2 case selection standards
(1) discontinuity stomachache, abdominal distention, diarrhoea, particularly after cold, the maror of food and more obvious after anxious state of mind; (2) times of defecation increases, and hepatic portal pendant pain obviously; (3) during acute attack, patient occurs that height is warm, abdominal part has an intense pain; (4) stool is in water sample even mucosanguineous feces; (5) General Symptoms can have face jaundice, lethargy, limbs fatigue, and severe patient can have dehydration, acidosis, shock performance.
1.3 Therapeutic Method
All patients are divided into treatment group and matched group at random, and two groups of patients, in sex, the state of an illness, the course of disease etc., through statistical procedures no significant difference (P > 0.05), have comparability.Wherein treatment group takes gained medicine of the present invention, observes three courses for the treatment of of treatment altogether.Matched group takes other drug (as conventional medicines such as Spleen Invigorating and Intestine Tonifying Pill, norfloxacin, CHANGYANNING PIAN).
1.4 curative effect determinate standard
Cure: subjective symptoms and sign disappear, normally, enteroscopy is without obvious enteritis pathological phenomenon for diet, stool; Effective: subjective symptoms and sign disappear, but coherence check still has colitis pathological phenomenon to exist; Effective: subjective symptoms obviously alleviates, but often have repeatedly, and check that pathological phenomenon is without obvious change; Invalid: symptom is without improvement or improve not obvious.
1.5 therapeutic outcome
Result is as shown in table 1.
Table 1: the therapeutic outcome for the treatment of group and matched group enteritis patient
Therapeutic effect: clinical cure 136 example (68%), effective 44 examples (22%), effective 18 examples (9%), invalid 2 examples (1%), total effective rate 99%.Treatment group successful is better than matched group.
The present invention select the Cortex Eucommiae, Radix Notoginseng, Herba Sonchi Arvensis, the Radix Paeoniae Alba, Herba Polygalae Japonicae, Semen Myristicae, Spica Prunellae, Folium Baeckeae, Gentiana rhodantha Franch. and Herba Hyperici Japonici etc. totally 15 taste primary raw material medicines be prepared from.Fang Zhong, the Cortex Eucommiae has invigorating the liver and kidney, effect of bone and muscle strengthening; Radix Notoginseng dissipating blood stasis stops blooding, subduing swelling and relieving pain; Herba Sonchi Arvensis heat-clearing and toxic substances removing, tonify deficiency cough-relieving; The pain relieving of Radix Paeoniae Alba suppressing the hyperactive liver; Semen Myristicae warming middle-JIAO, the therapeutic method to keep the adverse QI flowing downwards, helps digestion, Gu intestinal; Spica Prunellae relieves inflammation or internal heat improving eyesight, mass dissipating and swelling eliminating; Folium Baeckeae blood stasis removing, pain relieving, diuresis; Gentiana rhodantha Franch. clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body.All medicines share, and strengthen the merit of heat-clearing and toxic substances removing, invigorating the spleen and benefiting QI, solid intestinal pain relieving.After treating three courses for the treatment of, treatment group total effective rate is 99%, and matched group is only 78.2%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the invigorating the spleen and benefiting QI preparation of enteritis, it is characterized in that, be prepared from by following bulk drugs, be weight portion: Cortex Eucommiae 8-15; Radix Notoginseng 13-19; Herba Sonchi Arvensis 12-15; Radix Paeoniae Alba 8-12; Herba Polygalae Japonicae 7-16; Semen Myristicae 6-12; Spica Prunellae 9-15; Folium Baeckeae 12-17; Gentiana rhodantha Franch. 7-15; Herba Hyperici Japonici 12-19; Radix Pseudostellariae 9-16; Dry land willow 5-12; Bulbus Lilii 13-15; Herba Ecliptae 6-16; Bulbus Fritillariae Cirrhosae 5-11.
2. the invigorating the spleen and benefiting QI preparation for the treatment of enteritis as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Cortex Eucommiae 10-13; Radix Notoginseng 15-17; Herba Sonchi Arvensis 13-14; Radix Paeoniae Alba 9-11; Herba Polygalae Japonicae 10-13; Semen Myristicae 8-10; Spica Prunellae 11-13; Folium Baeckeae 13-16; Gentiana rhodantha Franch. 10-12; Herba Hyperici Japonici 14-17; Radix Pseudostellariae 12-13; Dry land willow 7-10; Bulbus Lilii 13.5-14.5; Herba Ecliptae 8-14; Bulbus Fritillariae Cirrhosae 7-9.
3. the invigorating the spleen and benefiting QI preparation for the treatment of enteritis as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: the Cortex Eucommiae 11.5; Radix Notoginseng 16; Herba Sonchi Arvensis 13.5; The Radix Paeoniae Alba 10; Herba Polygalae Japonicae 11.5; Semen Myristicae 9; Spica Prunellae 12; Folium Baeckeae 14.5; Gentiana rhodantha Franch. 11; Herba Hyperici Japonici 15.5; Radix Pseudostellariae 12.5; Dry land willow 8.5; Bulbus Lilii 14; Herba Ecliptae 11; Bulbus Fritillariae Cirrhosae 8.
4. the invigorating the spleen and benefiting QI preparation of the treatment enteritis as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable pill, preparation method is as follows:
(1) Bulbus Fritillariae Cirrhosae is cleaned, and removes the heart, is used as medicine in pot, and slow fire is fried to surface yellowish, drenches into Sucus Zingberis, continues to stir-fry to being buff, and taking-up cools, and pulverizes for subsequent use; Gentiana rhodantha Franch. sheet is placed in medicine pot, and moderate heat cures 6-10 minute (preferred slow fire cures 8 minutes), takes out, pulverizes for subsequent use;
(2) Semen Myristicae is cleaned, and is placed in the Fructus Jujubae of enucleation one by one, drops in the sand made popular, suitably stirs, and takes out, peel off Fructus Jujubae shell, smash to pieces when turning black to Fructus Corni, for subsequent use;
(3) Cortex Eucommiae, Radix Notoginseng, the Radix Paeoniae Alba and Radix Pseudostellariae are together placed in Chinese medicine grinder, are ground into fine powder, gained fine powder is mixed with step (1) and step (2) gained fine powder, sieves for subsequent use;
(4) Herba Sonchi Arvensis, Herba Polygalae Japonicae, Spica Prunellae, Folium Baeckeae, Herba Hyperici Japonici, dry land willow, Bulbus Lilii and Herba Ecliptae are adopted water extraction, adding clear water did not have powder to soak, then slow fire boiling twice, each respectively decoction 35-55 minute (preferably each each decoction 45 minutes), filter, collecting decoction; Medicinal residues add the ethanol extraction (preferably adding the ethanol extraction of 4 times amount) of 3-5 times amount, heating and refluxing extraction 20-30 minute (preferred heating and refluxing extraction 25 minutes), filter, collect filtrate, reclaim ethanol, merge with above-mentioned decocting liquid, continuing to be evaporated to 65 DEG C of relative densities is the thick paste of 1.10-1.13, for subsequent use;
(5) join in above-mentioned thick paste by step (3) gained mixing fine powders, add cane sugar powder and Fructus Crataegi powder simultaneously, mixing, is processed into the pill of Semen Firmianae size, obtains final product.
5. the preparation method of the invigorating the spleen and benefiting QI pill for the treatment of enteritis according to claim 4, is characterized in that, the middle 90-130 mesh sieve excessively of step (3) (preferred 100-120 mesh sieve excessively, mistake 110 mesh sieve be more preferably).
6. the preparation method of the invigorating the spleen and benefiting QI pill for the treatment of enteritis according to claim 4, it is characterized in that, the time of soaking in step (4) is 1.5-3.5 hour (the preferred time of soaking is 2-3 hour, and the time of the immersion be more preferably is 2.5 hours).
7. the preparation method of the invigorating the spleen and benefiting QI pill for the treatment of enteritis according to claim 4, it is characterized in that, in step (4), the mass concentration of added ethanol is the mass concentration of the preferred added ethanol of 65%-85%(is 70%-80%, and the mass concentration of the added ethanol be more preferably is 75%).
8. the invigorating the spleen and benefiting QI preparation of the treatment enteritis as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable decoction, preparation method is as follows:
(1) put in medicine pot by Semen Myristicae and Testa Tritici, slow fire heats, and stir-frying to Testa Tritici is coke yellow, when Semen Myristicae is dark-brown, takes out, removes Testa Tritici, smash to pieces for subsequent use; Get Fructus Schisandrae Chinensis and add water-wet, steam to bronzing, mix thoroughly (Fructus Schisandrae Chinensis: Mel=5:2) with Mel, reenter in steamer and steam to black for spending, taking-up cools, and smashs to pieces for subsequent use;
(2) get Cortex Eucommiae silk, add Chinese liquor and mix thoroughly, slightly moisten, be used as medicine in pot, moderate heat is fried to fracture of wire, surface coke black, takes out, cools completely, grind into powder for subsequent use;
(3) medical material step (1) and step (2) processed and surplus stock medicine are together placed in Chinese medicinal pot, add the pure water (preferably adding the pure water of 9 times amount) of 7-11 times amount, medicinal cupping is placed on stove fire, intense fire is heated to boil, turn slow fire boiling twice, first time decocts 1-1.5 hour (preferably first time decocts 1.3 hours), and second time decocts 35-45 minute (preferably second time decocts 40 minutes), filter, merge twice decocting liquid;
(4) above-mentioned decocting liquid is continued be concentrated into original volume 1/2,101 DEG C of dry heat sterilization 20-30 minute (preferably 101 DEG C dry heat sterilization 25 minutes), encapsulation, to obtain final product.
9. the invigorating the spleen and benefiting QI preparation of the treatment enteritis as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable granule, preparation method is as follows:
(1) take various crude drug by formula proportion, first clean, dry, then grind into powder, cross 100-140 mesh sieve (preferred mistake 120 mesh sieve), obtain mixed powder;
(2) in above-mentioned medicated powder, add sucrose fine and sodium cellulosate (medicated powder: sucrose fine: sodium cellulosate=4:1.3:1.1), do wetting agent, be placed in granulator and be processed into granule with the ethanol of 70%, cross No. four sieves, granulate, subpackage, to obtain final product.
10. the invigorating the spleen and benefiting QI preparation of the treatment enteritis as described in as arbitrary in claim 1-3, it is characterized in that, be made into pharmaceutically acceptable tablet, preparation method is as follows:
(1) take various crude drug by formula proportion, first clean, dry, then grind into powder, cross 80-120 mesh sieve (preferred mistake 100 mesh sieve), obtain mixed powder;
(2) above-mentioned medicated powder is measured according to 0.3-0.5g/ sheet (preferably according to 0.4g/ sheet), make tablet dosage form according to the preparation for processing of tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510088266.0A CN104623255A (en) | 2015-02-26 | 2015-02-26 | Spleen-invigorating and qi-supplementing preparation for treatment of enteritis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510088266.0A CN104623255A (en) | 2015-02-26 | 2015-02-26 | Spleen-invigorating and qi-supplementing preparation for treatment of enteritis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104623255A true CN104623255A (en) | 2015-05-20 |
Family
ID=53202817
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510088266.0A Pending CN104623255A (en) | 2015-02-26 | 2015-02-26 | Spleen-invigorating and qi-supplementing preparation for treatment of enteritis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104623255A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085331A (en) * | 2007-06-16 | 2007-12-12 | 房立海 | Capsule for treating enteritis |
| CN101461886A (en) * | 2009-01-13 | 2009-06-24 | 黑贺英 | Chinese medicinal pill for treating colonitis, and cough and asthma disease |
| CN102205105A (en) * | 2011-05-20 | 2011-10-05 | 济南金鼎信息技术有限公司 | Traditional Chinese medicine composition for treating chronic colitis |
-
2015
- 2015-02-26 CN CN201510088266.0A patent/CN104623255A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101085331A (en) * | 2007-06-16 | 2007-12-12 | 房立海 | Capsule for treating enteritis |
| CN101461886A (en) * | 2009-01-13 | 2009-06-24 | 黑贺英 | Chinese medicinal pill for treating colonitis, and cough and asthma disease |
| CN102205105A (en) * | 2011-05-20 | 2011-10-05 | 济南金鼎信息技术有限公司 | Traditional Chinese medicine composition for treating chronic colitis |
Non-Patent Citations (1)
| Title |
|---|
| 程刚: "慢性肠炎治疗体会", 《大家健康》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103830749B (en) | A kind of gastrointestinal contrast agent | |
| CN105232987A (en) | Traditional Chinese medicine promoting neurosurgery postoperative rehabilitation | |
| CN104906507A (en) | Traditional Chinese medicine combination for lowering blood pressure and toning physical fitness | |
| CN104984141A (en) | Prescription for treating constipation and preparation method thereof | |
| CN104983886A (en) | Traditional Chinese medicine preparation for treating constipation and preparing method thereof | |
| CN102178866A (en) | Chinese medicinal preparation for dispelling damp, promoting blood circulation, softening hard mass and eliminating stagnation for people with qi-depression and blood-stagnation physique, preparation method thereof and application thereof | |
| CN103860948A (en) | Traditional Chinese medicine for treating acute mastitis caused by qi stagnation and heat congestion and preparation method thereof | |
| CN103690816B (en) | Eliminate Chinese medicine composition of insufficiency of the spleen phlegm-damp Cystic hyperplasia of breast and preparation method thereof | |
| CN104623255A (en) | Spleen-invigorating and qi-supplementing preparation for treatment of enteritis and preparation method thereof | |
| CN104840758A (en) | Traditional Chinese medicine composition for treating dysmenorrheal and preparation method of traditional Chinese medicine composition | |
| CN105998979A (en) | Traditional Chinese medicine composition for treating lung-and-kidney-yin-deficiency-type chronic pharyngitis and method | |
| CN105663483A (en) | Traditional Chinese medicine composition for treating parasitic malnutrition type iron deficiency anemia and preparation method thereof | |
| CN104800687A (en) | Traditional Chinese medicine preparation for treating infantile malnutrition and preparation method thereof | |
| CN105125790A (en) | Qi regulating and stomach strengthening preparation for treating gasteremphraxis and preparation method of preparation | |
| CN105287933A (en) | Traditional Chinese medicine preparation capable of treating arteriosclerosis and invigorating spleen and supplementing qi and preparation method thereof | |
| CN104815267A (en) | Traditional Chinese medicine preparation capable of promoting digestion and relieving stasis to treat infantile indigestion with food retention | |
| CN104740396A (en) | Traditional Chinese medicine for treating kidney stones and preparation method of traditional Chinese medicine | |
| CN104667049A (en) | Traditional Chinese medicine preparation for treating pneumonia and preparation method of traditional Chinese medicine preparation | |
| CN104622984A (en) | Heat-clearing and dampness-removing preparation for patients suffering proctitis and preparation method thereof | |
| CN104623567A (en) | Blood circulation promoting and stasis removing traditional Chinese medicine preparation for treating breast cancer and preparation method of blood circulation promoting and stasis removing traditional Chinese medicine preparation | |
| CN104706866A (en) | Traditional Chinese medicine preparation for treating enteritis and preparation method of traditional Chinese medicine preparation | |
| CN104840670A (en) | Traditional Chinese medicine composition for treating dysmenorrhea | |
| CN104623610A (en) | Heat-clearing and dampness-resolving preparation for treating enteritis and preparation method thereof | |
| CN104623558A (en) | Medicine for soothing liver qi and resolving depression to treat mastitis | |
| CN104623247A (en) | Traditional Chinese medicine preparation for treatment of chronic enteritis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: 650000 Yunnan, Kunming, Xishan District Road, No. 12 Pearl Village District, building 2, 1-301 Applicant after: Wang Yan Address before: Hualong Road, Licheng District 250000 Shandong city of Ji'nan province No. 999 Fairview springs District Applicant before: Wang Yan |
|
| COR | Change of bibliographic data | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150520 |