CN104623245A - Heat-removing and salivation-promoting traditional Chinese medicine chewable tablet and preparation method thereof - Google Patents
Heat-removing and salivation-promoting traditional Chinese medicine chewable tablet and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicine, and discloses a heat-removing and salivation-promoting traditional Chinese medicine chewable tablet and a preparation method thereof. The traditional Chinese medicine chewable tablet comprises the following components in parts by weight: 8-16 parts of terminaliachebularetz aqueous extract, 5-12 parts of floschrysanthemiindici aqueous extract, 4-10 parts of ethanol extract from rabdosinserra(maxim) hara, 4-8 parts of ethanol extract from fritillariathunbergiimiq, 50wt% of vitexnegundolinn., 3-7 parts of ethanol aqueous extract, 15-25 parts of trichlorosucrose, 3-6 parts of magnesium stearate, 8-15 parts of maltodextrin. The preparation method comprises the following steps: grinding, aqueous extraction, extraction of ethanol extract and ethanol water solution, mixing and the like. The prepared traditional Chinese medicine chewable tablet has a good effect on removing heat and promoting salivation.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chewable Tablets of Chinese traditional medicine and preparation method thereof, particularly relate to Chewable Tablets of Chinese traditional medicine of a kind of clearing away heat and promoting production of body fluid and preparation method thereof.
Background technology
Chewable tablet refers to the tablet swallowed after chewing or suck clothes in oral cavity makes sheet dissolve, and often adds sucrose, Herba Menthae wet goods sweeting agent and flavorant adjustment taste, and through chewing, rear surface is long-pending to increase tablet, can promote medicine dissolving in vivo and absorption.Taking convenience, can swallow, chew containing sucking or taking with after aqueous dispersion.Through chewing, rear surface is long-pending to increase tablet, even if can promote that medicine dissolving in vivo and absorption also can ensure to take medicine on time under exsiccosis.The Chinese medicine of heat clearing away has Gypsum Fibrosum, Mirabilitum crystallina, the Rhizoma Anemarrhenae, Radix Trichosanthis, Folium Bambusae, Spica Prunellae, Rhizoma Phragmitis, Semen Celosiae, Flos Eriocauli, Flos Buddlejae, Flos Lonicerae, Folium Isatidis, silkworm stops, Herba Violae, Herba Houttuyniae, Herba Taraxaci, Herba Patriniae, the Radix Pulsatillae, Cortex Fraxini, Cortex Dictamni, Herba Portulacae, Radix Sophorae Tonkinensis, Fructus Bruceae, Rhizoma Belamcandae, Lasiosphaera Seu Calvatia, Radix Isatidis, Caulis Sargentodoxae, Rhizoma Smilacis Glabrae, Indigo Naturalis, Herba Hedyotidis Diffusae, Fructus Forsythiae, Radix Ampelopsis, Radix Rhapontici, Folium Ilicis Purpureae, Rhizoma Fagopyri Dibotryis, Semen phaseoli radiati, Calculus Bovis, Herba Sedi, Herba Andrographis, Herba Scutellariae Barbatae etc.The Chinese medicine promoted the production of body fluid has Flos Chrysanthemi, phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle eats, Radix Ophiopogonis, Folium Mori, Rhizoma Phragmitis, Herba Dendrobii, Fructus Jujubae, Radix Panacis Quinquefolii etc.
Summary of the invention
the technical problem solved:the technical problem to be solved in the present invention is to provide a kind of chewable tablet that can be used for removing body heat, slake thirst and help produce saliva, and is discharged by effective ingredient in chewable tablet by the mode of chewing, and improves the effect that it is removed body heat, slakes thirst and help produce saliva.
technical scheme:the invention discloses Chewable Tablets of Chinese traditional medicine of a kind of clearing away heat and promoting production of body fluid and preparation method thereof, the Chewable Tablets of Chinese traditional medicine of described clearing away heat and promoting production of body fluid comprises following compositions by weight:
FRUCTUS TERMINALIAE IMMATURUS water extract 8-16 part,
Flos Chrysanthemi Indici water extract 5-12 part,
Herba Rabdosiae Lophanthoidis ethanol extraction 4-10 part,
Fritillary flower ethanol extraction 4-8 part,
Fructus Viticis Negundo 50wt% ethanol-water extraction thing 3-7 part,
Sucralose 15-25 part,
Magnesium stearate 3-6 part,
Maltodextrin 8-15 part.
Preferably, the Chewable Tablets of Chinese traditional medicine of described a kind of clearing away heat and promoting production of body fluid, comprises following compositions by weight:
FRUCTUS TERMINALIAE IMMATURUS water extract 11-15 part,
Flos Chrysanthemi Indici water extract 7-10 part,
Herba Rabdosiae Lophanthoidis ethanol extraction 6-9 part,
Fritillary flower ethanol extraction 5-7 part,
Fructus Viticis Negundo 50wt% ethanol-water extraction thing 4-6 part,
Sucralose 18-22 part,
Magnesium stearate 4-5 part,
Maltodextrin 10-13 part.
Preferred further, the Chewable Tablets of Chinese traditional medicine of described a kind of clearing away heat and promoting production of body fluid, comprises following compositions by weight:
FRUCTUS TERMINALIAE IMMATURUS water extract 13 parts,
Flos Chrysanthemi Indici water extract 9 parts,
Herba Rabdosiae Lophanthoidis ethanol extraction 8 parts,
Fritillary flower ethanol extraction 6 parts,
Fructus Viticis Negundo 50wt% ethanol-water extraction thing 5 parts,
Sucralose 20 parts,
Magnesium stearate 5 parts,
Maltodextrin 12 parts.
A preparation method for the Chewable Tablets of Chinese traditional medicine of clearing away heat and promoting production of body fluid, comprises the following steps:
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, pulverizes respectively by FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici after vacuum drying, gets FRUCTUS TERMINALIAE IMMATURUS powder and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) get Herba Rabdosiae Lophanthoidis and Fritillary flower, will pulverize after two kinds of composition vacuum dryings again respectively, and pulverize most powder, the powder getting above-mentioned two kinds of compositions respectively carries out ethanol extraction, removing filtering residue after extraction, after clear liquid is concentrated, is Herba Rabdosiae Lophanthoidis ethanol extraction and Fritillary flower ethanol extraction;
(3) pulverized by Fructus Viticis Negundo, extract after pulverizing with 50wt% ethanol water, centrifugalize after extracting, by separating medium Vacuum film evaporation, collects Fructus Viticis Negundo 50wt% ethanol-water extraction thing after being evaporated solvent;
(4) FRUCTUS TERMINALIAE IMMATURUS water extract 8-16 part, Flos Chrysanthemi Indici water extract 5-12 part, Herba Rabdosiae Lophanthoidis ethanol extraction 4-10 part, Fritillary flower ethanol extraction 4-8 part, Fructus Viticis Negundo 50wt% ethanol-water extraction thing 3-7 part, sucralose 15-25 part, magnesium stearate 3-6 part, maltodextrin 8-15 part is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
The preparation method of the Chewable Tablets of Chinese traditional medicine of described a kind of clearing away heat and promoting production of body fluid, when in step (1), FRUCTUS TERMINALIAE IMMATURUS powder and Flos Chrysanthemi Indici powder extract with water respectively, feed liquid weight ratio is 1:8, and extraction time is 5h, and Extracting temperature is room temperature.
The preparation method of the Chewable Tablets of Chinese traditional medicine of described a kind of clearing away heat and promoting production of body fluid, when in step (2), Herba Rabdosiae Lophanthoidis and Fritillary flower are extracted with ethanol, feed liquid weight ratio is 1:10, and extraction time is 3h, and Extracting temperature is 45 DEG C.
The preparation method of the Chewable Tablets of Chinese traditional medicine of described a kind of clearing away heat and promoting production of body fluid, when in step (3), Fructus Viticis Negundo 50wt% ethanol water extracts, feed liquid weight ratio is 1:6, and extraction time is 2h, and Extracting temperature is 65 DEG C.
The preparation method of the Chewable Tablets of Chinese traditional medicine of described a kind of clearing away heat and promoting production of body fluid, in step (1), vacuum drying temperature is 50 DEG C.
beneficial effect:in the chewable tablet of clearing away heat and promoting production of body fluid of the present invention, effective ingredient comprises FRUCTUS TERMINALIAE IMMATURUS water extract, Flos Chrysanthemi Indici water extract, Herba Rabdosiae Lophanthoidis ethanol extraction, Fritillary flower ethanol extraction, Fructus Viticis Negundo 50wt% ethanol-water extraction thing, the clearing away heat and promoting production of body fluid effect of above-mentioned various extracts to chewable tablet has larger effect, has especially chanced on the Herba Rabdosiae Lophanthoidis ethanol extraction that adds and Fructus Viticis Negundo 50wt% ethanol-water extraction thing has very large effect to the effect improving this chewable tablet.
Detailed description of the invention
Embodiment 1
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, after vacuum drying, FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici are pulverized respectively, FRUCTUS TERMINALIAE IMMATURUS powder is got and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, feed liquid weight ratio is 1:8, and extraction time is 5h, and Extracting temperature is room temperature, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) Herba Rabdosiae Lophanthoidis and Fritillary flower is got, to pulverize after two kinds of composition vacuum dryings again respectively, pulverize most powder, the powder getting above-mentioned two kinds of compositions respectively carries out ethanol extraction, and feed liquid weight ratio is 1:10, and extraction time is 3h, Extracting temperature is 45 DEG C, removing filtering residue after extraction, after clear liquid is concentrated, is Herba Rabdosiae Lophanthoidis ethanol extraction and Fritillary flower ethanol extraction;
(3) pulverized by Fructus Viticis Negundo, extract with 50wt% ethanol water after pulverizing, feed liquid weight ratio is 1:6, extraction time is 2h, and Extracting temperature is 65 DEG C, centrifugalize after extracting, by separating medium Vacuum film evaporation, after being evaporated solvent, collect Fructus Viticis Negundo 50wt% ethanol-water extraction thing;
(4) FRUCTUS TERMINALIAE IMMATURUS water extract 16 parts, Flos Chrysanthemi Indici water extract 5 parts, Herba Rabdosiae Lophanthoidis ethanol extraction 10 parts, Fritillary flower ethanol extraction 8 parts, Fructus Viticis Negundo 50wt% ethanol-water extraction thing 3 parts, sucralose 25 parts, magnesium stearate 6 parts, maltodextrin 8 parts is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
Embodiment 2
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, after vacuum drying, FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici are pulverized respectively, FRUCTUS TERMINALIAE IMMATURUS powder is got and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, feed liquid weight ratio is 1:8, and extraction time is 5h, and Extracting temperature is room temperature, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) Herba Rabdosiae Lophanthoidis and Fritillary flower is got, to pulverize after two kinds of composition vacuum dryings again respectively, pulverize most powder, the powder getting above-mentioned two kinds of compositions respectively carries out ethanol extraction, and feed liquid weight ratio is 1:10, and extraction time is 3h, Extracting temperature is 45 DEG C, removing filtering residue after extraction, after clear liquid is concentrated, is Herba Rabdosiae Lophanthoidis ethanol extraction and Fritillary flower ethanol extraction;
(3) pulverized by Fructus Viticis Negundo, extract with 50wt% ethanol water after pulverizing, feed liquid weight ratio is 1:6, extraction time is 2h, and Extracting temperature is 65 DEG C, centrifugalize after extracting, by separating medium Vacuum film evaporation, after being evaporated solvent, collect Fructus Viticis Negundo 50wt% ethanol-water extraction thing;
(4) FRUCTUS TERMINALIAE IMMATURUS water extract 8 parts, Flos Chrysanthemi Indici water extract 12 parts, Herba Rabdosiae Lophanthoidis ethanol extraction 4 parts, Fritillary flower ethanol extraction 4 parts, Fructus Viticis Negundo 50wt% ethanol-water extraction thing 7 parts, sucralose 15 parts, magnesium stearate 3 parts, maltodextrin 15 parts is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
Embodiment 3
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, after vacuum drying, FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici are pulverized respectively, FRUCTUS TERMINALIAE IMMATURUS powder is got and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, feed liquid weight ratio is 1:8, and extraction time is 5h, and Extracting temperature is room temperature, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) Herba Rabdosiae Lophanthoidis and Fritillary flower is got, to pulverize after two kinds of composition vacuum dryings again respectively, pulverize most powder, the powder getting above-mentioned two kinds of compositions respectively carries out ethanol extraction, and feed liquid weight ratio is 1:10, and extraction time is 3h, Extracting temperature is 45 DEG C, removing filtering residue after extraction, after clear liquid is concentrated, is Herba Rabdosiae Lophanthoidis ethanol extraction and Fritillary flower ethanol extraction;
(3) pulverized by Fructus Viticis Negundo, extract with 50wt% ethanol water after pulverizing, feed liquid weight ratio is 1:6, extraction time is 2h, and Extracting temperature is 65 DEG C, centrifugalize after extracting, by separating medium Vacuum film evaporation, after being evaporated solvent, collect Fructus Viticis Negundo 50wt% ethanol-water extraction thing;
(4) FRUCTUS TERMINALIAE IMMATURUS water extract 11 parts, Flos Chrysanthemi Indici water extract 10 parts, Herba Rabdosiae Lophanthoidis ethanol extraction 6 parts, Fritillary flower ethanol extraction 7 parts, Fructus Viticis Negundo 50wt% ethanol-water extraction thing 4 parts, sucralose 22 parts, magnesium stearate 4 parts, maltodextrin 10 parts is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
Embodiment 4
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, after vacuum drying, FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici are pulverized respectively, FRUCTUS TERMINALIAE IMMATURUS powder is got and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, feed liquid weight ratio is 1:8, and extraction time is 5h, and Extracting temperature is room temperature, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) Herba Rabdosiae Lophanthoidis and Fritillary flower is got, to pulverize after two kinds of composition vacuum dryings again respectively, pulverize most powder, the powder getting above-mentioned two kinds of compositions respectively carries out ethanol extraction, and feed liquid weight ratio is 1:10, and extraction time is 3h, Extracting temperature is 45 DEG C, removing filtering residue after extraction, after clear liquid is concentrated, is Herba Rabdosiae Lophanthoidis ethanol extraction and Fritillary flower ethanol extraction;
(3) pulverized by Fructus Viticis Negundo, extract with 50wt% ethanol water after pulverizing, feed liquid weight ratio is 1:6, extraction time is 2h, and Extracting temperature is 65 DEG C, centrifugalize after extracting, by separating medium Vacuum film evaporation, after being evaporated solvent, collect Fructus Viticis Negundo 50wt% ethanol-water extraction thing;
(4) FRUCTUS TERMINALIAE IMMATURUS water extract 15 parts, Flos Chrysanthemi Indici water extract 7 parts, Herba Rabdosiae Lophanthoidis ethanol extraction 9 parts, Fritillary flower ethanol extraction 5 parts, Fructus Viticis Negundo 50wt% ethanol-water extraction thing 6 parts, sucralose 18 parts, magnesium stearate 5 parts, maltodextrin 13 parts is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
Embodiment 5
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, after vacuum drying, FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici are pulverized respectively, FRUCTUS TERMINALIAE IMMATURUS powder is got and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, feed liquid weight ratio is 1:8, and extraction time is 5h, and Extracting temperature is room temperature, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) Herba Rabdosiae Lophanthoidis and Fritillary flower is got, to pulverize after two kinds of composition vacuum dryings again respectively, pulverize most powder, the powder getting above-mentioned two kinds of compositions respectively carries out ethanol extraction, and feed liquid weight ratio is 1:10, and extraction time is 3h, Extracting temperature is 45 DEG C, removing filtering residue after extraction, after clear liquid is concentrated, is Herba Rabdosiae Lophanthoidis ethanol extraction and Fritillary flower ethanol extraction;
(3) pulverized by Fructus Viticis Negundo, extract with 50wt% ethanol water after pulverizing, feed liquid weight ratio is 1:6, extraction time is 2h, and Extracting temperature is 65 DEG C, centrifugalize after extracting, by separating medium Vacuum film evaporation, after being evaporated solvent, collect Fructus Viticis Negundo 50wt% ethanol-water extraction thing;
(4) FRUCTUS TERMINALIAE IMMATURUS water extract 13 parts, Flos Chrysanthemi Indici water extract 9 parts, Herba Rabdosiae Lophanthoidis ethanol extraction 8 parts, Fritillary flower ethanol extraction 6 parts, Fructus Viticis Negundo 50wt% ethanol-water extraction thing 5 parts, sucralose 20 parts, magnesium stearate 5 parts, maltodextrin 12 parts is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
Comparative example 1
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, after vacuum drying, FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici are pulverized respectively, FRUCTUS TERMINALIAE IMMATURUS powder is got and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, feed liquid weight ratio is 1:8, and extraction time is 5h, and Extracting temperature is room temperature, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) Herba Rabdosiae Lophanthoidis and Fritillary flower is got, to pulverize after two kinds of composition vacuum dryings again respectively, pulverize most powder, the powder getting above-mentioned two kinds of compositions respectively carries out ethanol extraction, and feed liquid weight ratio is 1:10, and extraction time is 3h, Extracting temperature is 45 DEG C, removing filtering residue after extraction, after clear liquid is concentrated, is Herba Rabdosiae Lophanthoidis ethanol extraction and Fritillary flower ethanol extraction;
(3) FRUCTUS TERMINALIAE IMMATURUS water extract 16 parts, Flos Chrysanthemi Indici water extract 5 parts, Herba Rabdosiae Lophanthoidis ethanol extraction 10 parts, Fritillary flower ethanol extraction 8 parts, sucralose 25 parts, magnesium stearate 6 parts, maltodextrin 8 parts is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
Comparative example 2
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, after vacuum drying, FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici are pulverized respectively, FRUCTUS TERMINALIAE IMMATURUS powder is got and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, feed liquid weight ratio is 1:8, and extraction time is 5h, and Extracting temperature is room temperature, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) get Fritillary flower, will pulverize after vacuum drying again, pulverize most powder, the powder getting mentioned component carries out ethanol extraction, feed liquid weight ratio is 1:10, and extraction time is 3h, and Extracting temperature is 45 DEG C, removing filtering residue after extraction, after clear liquid is concentrated, is Fritillary flower ethanol extraction;
(3) pulverized by Fructus Viticis Negundo, extract with 50wt% ethanol water after pulverizing, feed liquid weight ratio is 1:6, extraction time is 2h, and Extracting temperature is 65 DEG C, centrifugalize after extracting, by separating medium Vacuum film evaporation, after being evaporated solvent, collect Fructus Viticis Negundo 50wt% ethanol-water extraction thing;
(4) FRUCTUS TERMINALIAE IMMATURUS water extract 16 parts, Flos Chrysanthemi Indici water extract 5 parts, Fritillary flower ethanol extraction 8 parts, Fructus Viticis Negundo 50wt% ethanol-water extraction thing 3 parts, sucralose 25 parts, magnesium stearate 6 parts, maltodextrin 8 parts is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
The chewable tablet of the above embodiments and comparative example after chewing, can very effective removing body heat, slake thirst and help produce saliva.Wherein, taken the best results after the chewable tablet of embodiment 5, embodiment 3 and embodiment 4 effect are taken second place, and the effect of embodiment 1 and embodiment 2 is more taken second place, and the Chewable Tablets of Chinese traditional medicine of comparative example 1 and comparative example 2 is after chewing, removing body heat, the effect of slaking thirst and help produce saliva are very not obvious.Therefore, the Herba Rabdosiae Lophanthoidis ethanol extraction that adds of the present invention and the clearing away heat and promoting production of body fluid function influence of Fructus Viticis Negundo 50wt% ethanol-water extraction thing two kinds of compositions to chewable tablet very large.
Claims (8)
1. a Chewable Tablets of Chinese traditional medicine for clearing away heat and promoting production of body fluid, is characterized in that the Chewable Tablets of Chinese traditional medicine of described clearing away heat and promoting production of body fluid comprises following compositions by weight:
FRUCTUS TERMINALIAE IMMATURUS water extract 8-16 part,
Flos Chrysanthemi Indici water extract 5-12 part,
Herba Rabdosiae Lophanthoidis ethanol extraction 4-10 part,
Fritillary flower ethanol extraction 4-8 part,
Fructus Viticis Negundo 50wt% ethanol-water extraction thing 3-7 part,
Sucralose 15-25 part,
Magnesium stearate 3-6 part,
Maltodextrin 8-15 part.
2. the Chewable Tablets of Chinese traditional medicine of a kind of clearing away heat and promoting production of body fluid according to claim 1, is characterized in that the Chewable Tablets of Chinese traditional medicine of described clearing away heat and promoting production of body fluid comprises following compositions by weight:
FRUCTUS TERMINALIAE IMMATURUS water extract 11-15 part,
Flos Chrysanthemi Indici water extract 7-10 part,
Herba Rabdosiae Lophanthoidis ethanol extraction 6-9 part,
Fritillary flower ethanol extraction 5-7 part,
Fructus Viticis Negundo 50wt% ethanol-water extraction thing 4-6 part,
Sucralose 18-22 part,
Magnesium stearate 4-5 part,
Maltodextrin 10-13 part.
3. the Chewable Tablets of Chinese traditional medicine of a kind of clearing away heat and promoting production of body fluid according to claim 1, is characterized in that the Chewable Tablets of Chinese traditional medicine of described clearing away heat and promoting production of body fluid comprises following compositions by weight:
FRUCTUS TERMINALIAE IMMATURUS water extract 13 parts,
Flos Chrysanthemi Indici water extract 9 parts,
Herba Rabdosiae Lophanthoidis ethanol extraction 8 parts,
Fritillary flower ethanol extraction 6 parts,
Fructus Viticis Negundo 50wt% ethanol-water extraction thing 5 parts,
Sucralose 20 parts,
Magnesium stearate 5 parts,
Maltodextrin 12 parts.
4. a preparation method for the Chewable Tablets of Chinese traditional medicine of clearing away heat and promoting production of body fluid, is characterized in that, the preparation method of the Chewable Tablets of Chinese traditional medicine of described clearing away heat and promoting production of body fluid comprises the following steps:
(1) FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici is got, vacuum drying, pulverizes respectively by FRUCTUS TERMINALIAE IMMATURUS and Flos Chrysanthemi Indici after vacuum drying, gets FRUCTUS TERMINALIAE IMMATURUS powder and Flos Chrysanthemi Indici powder extracts with water respectively after pulverizing, extract rear filter-cloth filtering, after vacuum concentration, obtain FRUCTUS TERMINALIAE IMMATURUS extract and Flos Chrysanthemi Indici extract respectively;
(2) get Herba Rabdosiae Lophanthoidis and Fritillary flower, will pulverize after two kinds of composition vacuum dryings again respectively, and pulverize most powder, the powder getting above-mentioned two kinds of compositions respectively carries out ethanol extraction, removing filtering residue after extraction, after clear liquid is concentrated, is Herba Rabdosiae Lophanthoidis ethanol extraction and Fritillary flower ethanol extraction;
(3) pulverized by Fructus Viticis Negundo, extract after pulverizing with 50wt% ethanol water, centrifugalize after extracting, by separating medium Vacuum film evaporation, collects Fructus Viticis Negundo 50wt% ethanol-water extraction thing after being evaporated solvent;
(4) FRUCTUS TERMINALIAE IMMATURUS water extract 8-16 part, Flos Chrysanthemi Indici water extract 5-12 part, Herba Rabdosiae Lophanthoidis ethanol extraction 4-10 part, Fritillary flower ethanol extraction 4-8 part, Fructus Viticis Negundo 50wt% ethanol-water extraction thing 3-7 part, sucralose 15-25 part, magnesium stearate 3-6 part, maltodextrin 8-15 part is got by weight respectively, by above-mentioned each composition mix homogeneously, tabletting after mix homogeneously is the Chewable Tablets of Chinese traditional medicine of the clearing away heat and promoting production of body fluid of preparation after dry.
5. the preparation method of the Chewable Tablets of Chinese traditional medicine of a kind of clearing away heat and promoting production of body fluid according to claim 4, it is characterized in that, when in step (1), FRUCTUS TERMINALIAE IMMATURUS powder and Flos Chrysanthemi Indici powder extract with water respectively, feed liquid weight ratio is 1:8, extraction time is 5h, and Extracting temperature is room temperature.
6. the preparation method of the Chewable Tablets of Chinese traditional medicine of a kind of clearing away heat and promoting production of body fluid according to claim 4, is characterized in that, when in step (2), Herba Rabdosiae Lophanthoidis and Fritillary flower are extracted with ethanol, feed liquid weight ratio is 1:10, and extraction time is 3h, and Extracting temperature is 45 DEG C.
7. the preparation method of the Chewable Tablets of Chinese traditional medicine of a kind of clearing away heat and promoting production of body fluid according to claim 4, is characterized in that, when in step (3), Fructus Viticis Negundo 50wt% ethanol water extracts, feed liquid weight ratio is 1:6, and extraction time is 2h, and Extracting temperature is 65 DEG C.
8. the preparation method of the Chewable Tablets of Chinese traditional medicine of a kind of clearing away heat and promoting production of body fluid according to claim 4, is characterized in that, in step (1), vacuum drying temperature is 50 DEG C.
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| CN (1) | CN104623245A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771611A (en) * | 2012-08-22 | 2012-11-14 | 李娴 | Liver-fire-removing and eyesight-improving tea |
| CN104056145A (en) * | 2014-06-24 | 2014-09-24 | 张晓� | Traditional Chinese medicinal preparation for treating cough |
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2015
- 2015-02-12 CN CN201510072521.2A patent/CN104623245A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102771611A (en) * | 2012-08-22 | 2012-11-14 | 李娴 | Liver-fire-removing and eyesight-improving tea |
| CN104056145A (en) * | 2014-06-24 | 2014-09-24 | 张晓� | Traditional Chinese medicinal preparation for treating cough |
Non-Patent Citations (3)
| Title |
|---|
| 房学贤等: "《中西医结合眼耳鼻喉口齿科临床手册》", 31 January 2014, 安徽科学技术出版社 * |
| 罗国庆等: "中药超声雾化吸入治疗慢性咽炎50例疗效观察", 《浙江中医学院学报》 * |
| 郭鹏举等: "《中国非处方药完全手册》", 31 May 2005, 陕西科学技术出版社 * |
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