CN104606597A - Traditional Chinese medicinal composition for treating traumatic injury - Google Patents
Traditional Chinese medicinal composition for treating traumatic injury Download PDFInfo
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- CN104606597A CN104606597A CN201510075657.9A CN201510075657A CN104606597A CN 104606597 A CN104606597 A CN 104606597A CN 201510075657 A CN201510075657 A CN 201510075657A CN 104606597 A CN104606597 A CN 104606597A
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating traumatic injury. The composition consists of 20 traditional Chinese medicines, namely tinospora sinensis merr, heterosmilax japonica kunth, clerodendron cyrtophyllum, pegia sarmentosa, philippine flemingia root, gynostemma pentaphylla, munronia henryi harms, perilla leaf, dichidia tonkinensis costantin, adina racemosa, lysimachia paridiformis Franch, clerodendrum serratum var amplexifolium, rhinacanthus nasutus, blumea balsamifera, girardinia palmate, longpeduncle kadsura root, ardisia mamillata hance, uncaria rhynchophylla, rhizoma smilacis glabrae and piper boehmeriaefolium var. tonkinense. The traditional Chinese medicinal composition disclosed by the invention has functions of promoting blood circulation to remove stasis, relieving swelling and pain, unblocking channels and activating collaterals, and promoting reunion of fractured tendons and bones, and is applicable to soft tissue injury, tendon or joint strain and the like from falls, fractures, contusions, collisions or other reasons; and the traditional Chinese medicinal composition is convenient in using, rapid to take effect and significant in curative effect.
Description
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of Chinese medicine composition for the treatment of traumatic injury.
Background technology
Traumatic injury is modal illness on surgical clinical, mostly be extraneous violence factor and directly or indirectly act on body, people is because of the soft tissue injury caused by reasons such as falling, beat, touch, knock for general reference, and patient often requires treatment in time after ill, to eliminate the pain of injury as early as possible, get well.The main manifestations of traumatic injury is the livid purple addiction speckle of body local pain, swelling, dysfunction and subcutaneous appearance or hematoma, its pathological change with topical acute traumatic inflammation and tissue repair for principal character.Modern medicine mainly takes the Therapeutic Method such as wrapping, partial closure, physical therapy, application anti-inflammation analgesis medicament to traumatic injury, but these methods remain the problems such as not good enough in curative effect, rehabilitation duration is longer at present.
The traditional Chinese medical science is just studied traumatic injury from ancient times, has more complete understanding to its etiology and pathogenesis and Therapeutic Method, is its main rule for the treatment of with blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain.Common clever tincture as swollen in pain, prescription is: fragrant 15g in bean leaf ball, four directions veneer 50g, Radix Schefflerae Arboricolae 50g, Stephania cepharatha Hayata 35g, HEICHUIFENG 40g, Lignum Sappan 5g, Caulis Bauhihiae Championii 50g, Ramulus Et Folium Adhatodae Vasicae 5g, Radix Flemingiae Philippinensis 5g, Ramulus Cinnamomi 5g, Herba Gendarussae 5g, Herba Adenosmae 5g, Millettia Speciosa 5g, Folium Et Cacumen Murrayae 5g, Znnthoxylam armatum armatam DC 10g, Radix Stephaniae Tetrandrae 10g, Balsamiferou Blumea Herb 15g, Rhizoma Drynariae 10g, little wind Chinese mugwort 15g, Radix Aucklandiae 15g, Radix Angelicae Dahuricae 15g, Rhizoma Curcumae Longae 2.5g, Radix Ardisiae Crenatae 25g, Radix seu Caulis Embeliae Parviflorae 25g, Caulis et Folium fici Tikouae 25g, Herba Blumeae Laciniatae 25g, Fructus Gleditsiae Abnormalis 25g, Rhizoma Cyperi 25g, Herba Penthori chinensis 25g, Gaster Sus domestica veneer 50g, Caulis Spatholobi 50g, Borneolum Syntheticum 15g, Camphora 35g, Mentholum 35g, function cures mainly as expelling wind and removing dampness, reducing swelling and alleviating pain, for rheumatic ostalgia, traumatic injury.Conventional also has repercussive and analgesic tincture, prescription is: Radix Aucklandiae 71g, Radix Saposhnikoviae 71g, Herba Schizonepetae 71g, Herba Asari 71g, Cortex Acanthopancis 71g, Ramulus Cinnamomi 71g, Radix Achyranthis Bidentatae 71g, Rhizoma Chuanxiong 71g, Radix Cynanchi Paniculati 71g, Radix Angelicae Dahuricae 0-1171g, Rhizoma Curcumae 71g, Radix seu Caulis Parabarii 106g, DALUOSAN 152g, Radix Ardisiae punctatae 106g, Radix Zanthoxyli 152g, Caulis Fibraureae 144g, Fructus Gardeniae 152g, Rhizoma Sparganii 106g, Lignum Aquilariae Resinatum 49g, Camphora 83g, Mentholum 83g, function cures mainly as relaxing muscles and tendons and activating QI and blood in the collateral, reducing swelling and alleviating pain, for osteopatia sprain, rheumatic ostalgia, innominate toxic swelling, parotitis swells and ache.Application number is the Chinese patent of CN99105072.X, disclose a kind of Chinese herbal and crude drugs preparations powdered repellent-antalgesic medicine, it is made up of Radix Notoginseng, Radix Clematidis, Squama Manis, Margarita, Herba Violae, Flos Carthami, Venenum Bufonis, Flos Caryophylli, pollen, Radix Cocculi Orbiculati, Radix Angelicae Sinensis, Moschus, Lignum Sappan, Sanguis Draxonis, Olibanum, Myrrha etc., effective in cure to illness such as furuncle and phyma abscess, rheumatism, hyperosteogenys.But there is the therapeutic process time and grow and be difficult to reach desirable therapeutic effect in the treatment of above-mentioned medicine for external use.The present invention adopts traditional Chinese medicine composition for treating, for inventor practises medicine experience accumulation, constantly perfect achievement for many years, through pharmacology and clinical research, can more effective alleviation traumatic injury cause swelling, pain, alleviate patient suffering, had not yet to see relevant report.
(1) Herba Lycopodii is the dry stem of menispermaceae plant lobus cardiacus Herba Lycopodii Tinospora cordifolia (wulld) Miers or Herba Lycopodii T.sin-ensis (Lour.) Merr..[nature and flavor with return through] are bitter, puckery, cool.[function with cure mainly] clearing heat and moistening lung, blending pathology is caused disorderly.For liver-heat, visceral heat, pneumonopathy, rheumatic arthritis, ageing diseases.
(2) nine Niu Li are the dry root stock of Smilacaceae plant China Xiao Rhizoma Smilacis Chinensis Heterosmilax chinensis Wang.[nature and flavor] are bitter, pungent, flat.[function with cure mainly] is dispeled the wind, is invigorated blood circulation.For rheumatic lumbago and scelalgia, traumatic injury.
(3) Folium Isatidis is stem, the leaf of Verbenaceae Folium Isatidis Cleredendrum cwtophyllum Turcz..[nature and flavor] are bitter; Cold.[return through] stomach; Heart channel.[function cures mainly] heat-clearing and toxic substances removing; Cooling blood for hemostasis.Main fever caused by exogenous pathogenic factors intenseness of heat excessive thirst; Laryngopharynx swelling and pain; Aphtha; Jaundice; Pyrotoxic dysentery; Acute enteritis; Swollen ulcer drug; Epistaxis; Stranguria with blood; Traumatic hemorrhage.
(4) sharp Caulis Fibraureae is stem, the leaf of Anacardiaceae plant profit Caulis Fibraureae Pegia sarmentosa (Lecte.) Hand.-Mazz..[nature and flavor] acid; Flat.[function cures mainly] clearing away damp-heat; Removing toxic substances.Main jaundice due to damp-heat; Beriberoid pyretic arthralgia; Carbuncle and ulcer; Eczema; Venom.
(5) Radix Flemingiae Philippinensis is leguminous plant Radix Flemingiae Philippinensis Moghania philippinensis (Merr.et Rolfe) Li, Flemingia macrophylla Moghania macrophylla (Willd.) O.Kuntze, root.[nature and flavor] are sweet; Puckery; Flat.[return through] lung; Kidney; Urinary bladder channel.[function cures mainly] expelling wind and removing dampness; Bone and muscle strengthening; Promoting blood circulation and detoxication.Main air pain of dampness syndrome; Lumbar muscle strain; Extremity flaccidity is soft; Traumatic injury; Laryngopharynx swelling and pain.
(6) Herb Gynostemmae Pentaphylli is the dry aerial parts of cucurbitaceous plant Herb Gynostemmae Pentaphylli Gynostemma pentaphyllum (Thunberg) Makino.[nature and flavor with return through] are bitter, micro-sweet, cool.Return lung, spleen, kidney channel.[function with cure mainly] tonify deficiency, heat clearing away, removing toxic substances.Weak for body void, nephrasthenia emission, leukopenia, hyperlipemia, viral hepatitis, chronic gastroenteritis, chronic tracheitis.
(7) short top top, Meliaceae Herba Munroniae henryi platymiscium munronia henryi Harms Munronia henryi Harms, the Herb of Yunnan Herba Munroniae henryi Munronia delavayi Franch..[nature and flavor] pungent, micro-hardship, cool.Slightly poisonous.[function cures mainly] relaxing muscles and tendons and activating QI and blood in the collateral, wind-expelling pain-stopping, antipyretic preventing the attack (or recurrence) of malaria.For traumatic injury, rheumatic arthritis, stomachache, flatulence is suffered from abdominal pain, cold, fever, malaria.
(8) Folium Perillae is the dried leaves (or band twig) of labiate Folium Perillae Perilla frutescens (L.) Britt.[nature and flavor with return through] are pungent, temperature.Return lung, spleen channel.[function with cure mainly] induce sweat cold expelling, relieving QI stagnancy in the stomach.For anemofrigid cold, cough vomiting and nausea, vomiting during pregnancy, fish Eriocheir sinensis is poisoning.
(9) milk rattan is the Herb of asclepiadaceae plant Herba Dischidiae Chinensis Dichidia tonkinensis Costantin.[nature and flavor] are sweet, micro-hardship, cool in nature.[function cures mainly] removing heat-phlegm, removing pathogenic heat from blood and toxic substance from the body.Control lung-heat hemoptysis, infantile malnutrition, dysentery, furuncle furuncle skin ulcer.
(10) Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. is the Herb of young wooden Adina racemosa (Sieb.Et Zucc.) Miq. of Maguireothamnus speciosus chicken.[nature and flavor] are bitter; Cool.[function with cure mainly] heat-clearing and toxic substances removing; Promoting blood circulation to remove blood stasis.Main cold, fever; Cough due to lung-heat; Gastroenteritis; Dysentery; Acute toothache; Swollen ulcer drug; Eczema; Traumatic injury; Traumatic hemorrhage.
(11) Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) is the herb of Ofthe Primulaceae Herba lysimachiae Paridiformis Lysimachia paridiformis Franch.[nature and flavor] are pungent; Bitter; Warm in nature.[function with cure mainly] expelling wind and removing dampness; Promoting blood circulation and stopping pain; Cough-relieving; Removing toxic substances.Main rheumatalgia; Epigastric pain; Cough; Traumatic injury; Furuncle and phyma treats skin ulcer; Venom.
(12) Herba Clerodendri Serrati, for Verbenaceae three is to the Herb of joint Clerodendrum serratum (L.) Moon, three colored Clerldendrum serratum (L.) Moon var.amplexifotium Moldenke.[nature and flavor] toil; Cool; Slightly poisonous.[return through] spleen; Kidney channel.[function cures mainly] clearing away heat-damp and promoting diuresis; Eliminating stasis to stop pain; Removing toxic substances and promoting subsidence of swelling.Main hygropyretic dysentery; Stranguria; Beriberoid pyretic arthralgia; Dysmenorrhea due to blood stasis; Traumatic injury; Laryngopharynx swelling and pain; Swollen ulcer drug; Urticaria; Malaria.
(13) Ramulus et Folium Rhinacanthi nasuti is branch, the leaf of acanthaceous plant Ramulus et Folium Rhinacanthi nasuti Rhinacanthus nasutus (Linn.) Lindau.[nature and flavor] sweet in the mouth; Micro-hardship; Cold nature.[return through] lung meridian.[function cures mainly] clearing heat and moistening lung; Killing parasites for relieving itching.Main chronic cough; Scabies; Eczema.
(14) Herba Blumeae Balsamiferae is the herb of feverfew Herba Blumeae Balsamiferae Blumea balsamifera (L.) DC..[nature and flavor] acrid in the mouth; Micro-hardship; Warm in nature.[function cures mainly] expelling wind and removing dampness; Warming middle-JIAO to stop diarrhea; Promoting blood circulation and detoxication.Main anemofrigid cold; Wind syndrome of head is had a headache; Rheumatic arthralgia; Cold-damp dysentery; Taeniasis; Venom; Traumatic pain; Tinea skin ulcer.
(15) Herba Girardiniae Palmatae is Urticaceae girardinia plant Herba Girardiniae Palmatae Girardinia palmata (Forsk.) Gaud., with all herbal medicine.The whole year can adopt, using fresh herb or dry.[nature and flavor] are bitter, pungent, cool.Poisonous.[function with cure mainly] eliminates the phlegm, dampness removing, removing toxic substances.For cough with copious phlegm, edema.Sore is controlled in external.
(16) Radix Kadsurae longipedunculatae is root or the root bark of Schisandraceae Plant Kadsura Longepedunculata Kadsura longipedunculata Finet etGagn..[nature and flavor] are pungent; Bitter; Warm in nature.[return through] spleen; Stomach; Liver Channel.[function cures mainly] regulating QI to relieve pain; To dispel people's dredging collateral; Promoting blood circulation and detumescence.Main stomachache; Stomachache; Rheumatic arthralgia; Dysmenorrhea; Menoxenia; Puerperal abdonimal pain; Laryngopharynx swelling and pain; Hemorrhoid; Innominate toxic swelling; Traumatic injury.
(17) Ardisia mamillata is the Herb of Myrsinacea plant Ardisia mamillata Ardisia mamillata Hance.[nature and flavor] are bitter; Pungent; Cool in nature.[function cures mainly] dispel the wind scrape wet; Heat-clearing and toxic substances removing; Promoting blood circulation and hemostasis.Main air pain of dampness syndrome; Yellow cellulitis; Dysentery; Hemoptysis; Spit blood; Have blood in stool; Amenorrhea; Prolonged lochia; Traumatic injury; Mastalgia; Treat skin ulcer.
(18) Ramulus Uncariae Cum Uncis is the dry stem and branch with belt hook of Maguireothamnus speciosus Ramulus Uncariae Cum Uncis Uncaria rhynchophylla (Miq.) Miq.ex Havil, Ramulus Uncariae macrophyllae Uncaria.macrophylla Wall., Ramulus Uncariae Cum Uncis Uncaria hirsuta Havil., Uncaria sinensis (Oliv.) Havil. Uncaria sinensis (Oliv) Havil. or stockless fruit Ramulus Uncariae Cum Uncis Uncaria sessilifructus Roxb..[nature and flavor with return through] are sweet, cool.Return liver, pericardium channel.[function with cure mainly] dispelling wind and relieving convulsion, heat clearing away suppressing the hyperactive liver.For liver-wind stirring up internally, infantile convulsion is twitched, and hyperpyrexia convulsion, dysphoric cold, children's's night crying due to fright in infant, pre-eclampsia, has a headache dizzy.
(19) Rhizoma Smilacis Glabrae is the dry rhizome of liliaceous plant smilacis glabra Smilar glabra Roxb..[nature and flavor with return through] are sweet, light, flat.Return liver, stomach warp.[function with cure mainly] detoxify, dehumidifies, easing joint movement.For the limbs contracture caused by syphilis and mercurialism, bones and muscles pain; Damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies.
(20) optical axis ramie leaf Betel is the Herb of Piperaceae plant optical axis ramie leaf Betel Piper boehmeriaefolium (Miq.) C.DC.var.tomkinense C.DC..[nature and flavor] are pungent; Temperature.[return through] Liver Channel.[function cures mainly] expelling wind and cold; Promoting blood flow to regulate menstruation; Reducing swelling and alleviating pain.Main anemofrigid cold, rheumatic arthralgia, coldness and pain in the epigastrium, toothache, menoxenia, pain is exhausted, treating swelling and pain by traumatic injury, snake bite and insect sting.
Summary of the invention
The invention provides the Chinese medicine composition of swelling that a kind of more effective alleviation traumatic injury causes, pain, this Chinese medicine composition energy blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, soothing the channels and quicking the network vessels, effect is faster, evident in efficacy.Technical scheme of the present invention is:
A kind of Chinese medicine composition for the treatment of traumatic injury, be made up of the Chinese medicine of following weight portion: Herba Lycopodii 20-35 part, nine Ns of power 30-45 parts, Folium Isatidis 40-60 part, profit Caulis Fibraureae 70-90 part, Radix Flemingiae Philippinensis 30-50 part, Herb Gynostemmae Pentaphylli 70-90 part, short holder many 15-35 part, Folium Perillae 40-60 part, milk rattan 20-35 part, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 20-40 part, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15-35 part, three colored 50-70 parts, Ramulus et Folium Rhinacanthi nasuti 70-90 part, Herba Blumeae Balsamiferae 70-90 part, Herba Girardiniae Palmatae 30-50 part, Radix Kadsurae longipedunculatae 50-70 part, Mao Jingang 15-25 part, Ramulus Uncariae Cum Uncis 40-60 part, Rhizoma Smilacis Glabrae 15-30 part, optical axis Zhu Ye Betel 70-90 part.
The Chinese medicine composition of the above treatment traumatic injury, is preferably made up of the Chinese medicine of following weight portion: Herba Lycopodii 25 parts, nine Ns of power 35 parts, Folium Isatidis 50 parts, sharp Caulis Fibraureae 80 parts, Radix Flemingiae Philippinensis 40 parts, Herb Gynostemmae Pentaphylli 80 parts, many 25 parts of short holder, Folium Perillae 50 parts, 25 parts, milk rattan, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 30 parts, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 25 parts, three spend 60 parts, Ramulus et Folium Rhinacanthi nasuti 80 parts, Herba Blumeae Balsamiferae 80 parts, Herba Girardiniae Palmatae 40 parts, Radix Kadsurae longipedunculatae 60 parts, Mao Jingang 20 parts, Ramulus Uncariae Cum Uncis 50 parts, Rhizoma Smilacis Glabrae 25 parts, optical axis ramie leaf Betel 80 parts.
The Chinese medicine composition of the above treatment traumatic injury, can take orally, also can external, can be made into any preparation pharmaceutically allowed.Described preparation is preferably emplastrum, ointment, gel, liniment, tincture, medicated wine, liniment or spray etc., best preferably tincture.
The Chinese medicine composition for the treatment of traumatic injury described in more than one makes the method for tincture, comprises the following steps:
1. take Chinese medicine by following weight portion: Herba Lycopodii 20-35 part, nine Ns of power 30-45 parts, Folium Isatidis 40-60 part, profit Caulis Fibraureae 70-90 part, Radix Flemingiae Philippinensis 30-50 part, Herb Gynostemmae Pentaphylli 70-90 part, short holder many 15-35 part, Folium Perillae 40-60 part, milk rattan 20-35 part, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 20-40 part, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15-35 part, three colored 50-70 parts, Ramulus et Folium Rhinacanthi nasuti 70-90 part, Herba Blumeae Balsamiferae 70-90 part, Herba Girardiniae Palmatae 30-50 part, Radix Kadsurae longipedunculatae 50-70 part, Mao Jingang 15-25 part, Ramulus Uncariae Cum Uncis 40-60 part, Rhizoma Smilacis Glabrae 15-30 part, optical axis Zhu Ye Betel 70-90 part,
2. more than, two Ten Herbs, are ground into coarse powder, use 60-90% ethanol as solvent, flood after 24-48 hour, with the speed of 1-3ml per minute slowly percolation, collect percolate, stir evenly, filter, to obtain final product.
The present invention is by Herba Lycopodii, nine Niu Li, Folium Isatidis, profit Caulis Fibraureae, Radix Flemingiae Philippinensis, Herb Gynostemmae Pentaphylli, short holder is many, Folium Perillae, milk rattan, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp., Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae), three flowers, Ramulus et Folium Rhinacanthi nasuti, Herba Blumeae Balsamiferae, Herba Girardiniae Palmatae, Radix Kadsurae longipedunculatae, Mao Jingang, Ramulus Uncariae Cum Uncis, Rhizoma Smilacis Glabrae, optical axis ramie leaf Betel is totally 20 taste Chinese medicine compositions, all medicines share, play blood circulation promoting and blood stasis dispelling altogether, reducing swelling and alleviating pain, soothing the channels and quicking the network vessels, the merit of reunion of fractured tendons and bones, can be used for because falling, beat, touch, the soft tissue injury caused by reason such as to knock, ligament or joint strain etc., eliminate patient's local pain, swelling, dysfunction and the symptom such as the livid purple addiction speckle of subcutaneous appearance or hematoma.External preparation made by prescription of the present invention, theoretical according to traditional Chinese medical science inner disease outer treat, makes medicine through acupuncture point and skin double-absorption, by shallow table channels, contact the twelve regular channels and run through whole body and reach disease institute, producing good therapeutic effect, is patient, particularly those not easily oral patients, a kind of new route of administration is provided, liver first-pass effect does not occur, do not affect by the factor such as gastric emptying and liver function, not easily produce incompatibility, avoid the untoward reaction that Long-term Oral medicine produces body.The present invention has effect rapidly, and the efficacy of a drug is lasting, applies easy, effectively can alleviate swelling that traumatic injury causes, pain, dysfunction and the symptom such as the livid purple addiction speckle of subcutaneous appearance or hematoma.The transparent clarification of obtained tincture, without precipitation, can be placed, good stability for a long time.
Detailed description of the invention
Below in conjunction with specific embodiment, the invention will be further described; but do not limit the scope of the invention and range of application: as used herein, " preferably " and variant thereof refer to the embodiment of the present invention that can provide specific beneficial effect in certain circumstances.But other embodiment also can be preferred under identical or other environment.In addition, the detailed description of one or more preferred embodiment does not represent that other embodiment is useless, and is not intended to the embodiment getting rid of other from category of the present invention.
One, the preparation of the Chinese medicine composite tincture of traumatic injury is treated
Embodiment 1
The Chinese medicine composition for the treatment of traumatic injury makes a method for tincture, comprises the following steps:
1. take Chinese medicine by following weight: Herba Lycopodii 2kg, nine Ns of power 3kg, Folium Isatidis 4kg, sharp Caulis Fibraureae 7kg, Radix Flemingiae Philippinensis 3kg, Herb Gynostemmae Pentaphylli 7kg, the many 1.5kg of short holder, Folium Perillae 4kg, milk rattan 2kg, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 2kg, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 1.5kg, three colored 5kg, Ramulus et Folium Rhinacanthi nasuti 7kg, Herba Blumeae Balsamiferae 7kg, Herba Girardiniae Palmatae 3kg, Radix Kadsurae longipedunculatae 5kg, Mao Jingang 1.5kg, Ramulus Uncariae Cum Uncis 4kg, Rhizoma Smilacis Glabrae 1.5kg, optical axis ramie leaf Betel 7kg;
2. more than, 23 taste Chinese medicines, are ground into coarse powder, use 60% ethanol as solvent, flood after 24 hours, with the speed of 1ml per minute slowly percolation, collect percolate, stir evenly, filter, to obtain final product.
Embodiment 2
The Chinese medicine composition for the treatment of traumatic injury makes a method for tincture, comprises the following steps:
1. take Chinese medicine by following weight: Herba Lycopodii 3.5kg, nine Ns of power 4.5kg, Folium Isatidis 6kg, sharp Caulis Fibraureae 9kg, Radix Flemingiae Philippinensis 5kg, Herb Gynostemmae Pentaphylli 9kg, the many 3.5kg of short holder, Folium Perillae 6kg, milk rattan 3.5kg, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 4kg, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 3.5kg, three colored 7kg, Ramulus et Folium Rhinacanthi nasuti 9kg, Herba Blumeae Balsamiferae 9kg, Herba Girardiniae Palmatae 5kg, Radix Kadsurae longipedunculatae 7kg, Mao Jingang 2.5kg, Ramulus Uncariae Cum Uncis 6kg, Rhizoma Smilacis Glabrae 3kg, optical axis ramie leaf Betel 9kg;
2. more than, 23 taste Chinese medicines, are ground into coarse powder, use 90% ethanol as solvent, flood after 48 hours, with the speed of 3ml per minute slowly percolation, collect percolate, stir evenly, filter, to obtain final product.
Embodiment 3
The Chinese medicine composition for the treatment of traumatic injury makes a method for tincture, comprises the following steps:
1. take Chinese medicine by following weight: Herba Lycopodii 2.5kg, nine Ns of power 3.5kg, Folium Isatidis 5kg, sharp Caulis Fibraureae 8kg, Radix Flemingiae Philippinensis 4kg, Herb Gynostemmae Pentaphylli 8kg, the many 2.5kg of short holder, Folium Perillae 5kg, milk rattan 2.5kg, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 3kg, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 2.5kg, three colored 6kg, Ramulus et Folium Rhinacanthi nasuti 8kg, Herba Blumeae Balsamiferae 8kg, Herba Girardiniae Palmatae 4kg, Radix Kadsurae longipedunculatae 6kg, Mao Jingang 2kg, Ramulus Uncariae Cum Uncis 5kg, Rhizoma Smilacis Glabrae 2.5kg, optical axis ramie leaf Betel 8kg;
2. more than, 23 taste Chinese medicines, are ground into coarse powder, use 70% ethanol as solvent, flood after 24 hours, with the speed of 2ml per minute slowly percolation, collect percolate, stir evenly, filter, to obtain final product.
Two, pharmacodynamics test
1. on the microcirculatory impact of Mice Auricle
Get mice, be divided into blank group (80% ethanol), positive controls (YUNNAN BAIYAO DING), embodiment group (embodiment 3 sample) at random, often organize 10.Each Mus lumbar injection pentobarbital sodium 25mg/kg, auricle hair is pruned with eye scissors after anesthesia, mice is fixed, open and flat auricle and be coated with a little cedar oil in surface, be placed on microscope carrier, with Mice Auricle microcirculation before 40 ~ 100 times of sem observation administrations, record each Mus auricle arteriole (A), the bore of thin vein (V), capillary open amount.Then be coated with outside left ear two sides and give corresponding tested medicinal liquid 0.1ml, administration after 30 minutes, then measures auricle arteriole (A), the bore of thin vein (V), capillary open amount.Result shows, embodiment group can make Mice Auricle arteriole (A), thin vein (V) external caliber obviously increases, and auricle capillary open increasing number, in table 1.
Table 1 is on the microcirculatory impact of Mice Auricle
2. on Carrageenan causes the impact of mice foot swelling
Get mice, every mice right back toes portion subcutaneous injection 0.5% carrageenin suspension 40 μ l causes inflammation.To cause mice random packet after inflammation, be divided into blank group (80% ethanol), positive controls (YUNNAN BAIYAO DING), embodiment group (embodiment 3 sample) at random, often organize 10.After grouping, mice starts administration, smears and gives corresponding test medicine 0.2ml, successive administration 3 days, every day 1 time in right back toes portion, in last administration after 4 hours, puts to death mice, gets rear biped and be equal to position, accurately weigh, using left and right foot weight difference as swelling.Result shows, embodiment group on Carrageenan causes mice foot swelling inflammation has obvious inhibitory action, in table 2.
Table 2 on Carrageenan causes the impact of mice toes inflammation
3. analgesic test
Get mice, be divided into blank group (80% ethanol), positive controls (YUNNAN BAIYAO DING), embodiment group (embodiment 3 sample) at random, often organize 10.The front hot plate method of medication measures the pain threshold of each mice.Each mice two hind leg is smeared and is given corresponding test medicine each 0.2ml, and after medicine, 20 minutes reusable heat plate methods measure the pain threshold of each Mus respectively.Result shows, embodiment group has obvious analgesic activity, in table 3.
Table 3 analgesic test
Three, clinical practice test
1. case selection
Select because of the soft tissue injury caused by reasons such as falling, beat, touch, knock, ligament or joint strain patient.
2. therapeutic scheme
Affected part warm water cleaning is dried, be stained with embodiment 3 sample with sterilized cotton ball or cotton swab embrocate affected part and be massaged into heating gently, every day 3 times, comparatively severe one can soak drug application subsides affected part with double gauze, with bandaging, and every day 3 times medicine is dropped in outside wrapping cloth and allow it infiltrate.One week was 1 course for the treatment of.Severe patient can adopt invention Chinese medicine composition to be decocted in water for oral dose.
3. clinical efficacy
Select 79 examples to meet the patient of above-mentioned case selection condition, man: 45 example, female: 34 example, the age: 10-65 year.The results detailed in following table.
Clinical efficacy survey result table
Clinical test results shows: adopt the above-mentioned case of traditional Chinese medicine composition for treating of the present invention, cure rate 92.4%, and effective percentage treats 100%, evident in efficacy, is showed no irritant reaction to normal and damaged skin, also there are no skin hypersensitivity reaction, and use safety.Illustrate that the present invention has the merit of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, soothing the channels and quicking the network vessels, reunion of fractured tendons and bones, can be used for because of soft tissue injury, ligament or the joint strain etc. caused by reasons such as falling, beat, touch, knock, eliminate patient's local pain, swelling, dysfunction and the symptom such as the livid purple addiction speckle of subcutaneous appearance or hematoma.
4. model case
(1) Jiang, man, 19 years old, student, because spraining at school's kicking foot, ankle place was red and swollen, pain, limitation of activity.Use the embodiment of the present invention 3 sample embrocate affected part and be massaged into heating gently, every day 3 times, after 3 days, redness disappears, pain relief, and after 5 days, pain disappears, and fully recovers, can normally walk and move after 7 days.
(2) appoint certain, female, 35 years old, causing right carpal joint swelling and pain, limitation of activity because getting injured by a fall, being diagnosed as right closed fracture of distal end of radius, right type joint swelling, tenderness, Pi Wen is slightly high, each dactylus limitation of activity.
Medicine of the present invention is adopted to take orally, prescription is: Herba Lycopodii 10g, nine Ns of power 15g, Folium Isatidis 20g, sharp Caulis Fibraureae 30g, Radix Flemingiae Philippinensis 20g, Herb Gynostemmae Pentaphylli 40g, the many 13g of short holder, Folium Perillae 25g, milk rattan 10g, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 10g, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15g, three colored 30g, Ramulus et Folium Rhinacanthi nasuti 40g, Herba Blumeae Balsamiferae 40g, Herba Girardiniae Palmatae 20g, Radix Kadsurae longipedunculatae 30g, Mao Jingang 10g, Ramulus Uncariae Cum Uncis 20g, Rhizoma Smilacis Glabrae 10g, optical axis ramie leaf Betel 40g, every day 1 pair, be decocted in water for oral dose, divide and take for 3 times, serve on 3.
Adopt the embodiment of the present invention 3 sample, paste affected part with double gauze leaching drug application, with bandaging, and every day 3 times medicine is dropped in outside wrapping cloth and allow it infiltrate.After 1 week, swelling, pain relief, swelling after 2 week, pain disappear, and after 3 week, articulations digitorum manus is normal without tenderness, activity, recovery from illness.
(3) Huang, man, 52 years old, construction site was removed weight and is dodged waist, caused left lumbar hurt like hell, stood up, difficulty in walking.Use the embodiment of the present invention 3 sample embrocate affected part and be massaged into heating gently, every day 3 times, pain relief after 3 days, can normally walk after 7 days, and after 2 week, pain disappears, and waist is movable normal, recovery from illness.
Claims (5)
1. treat the Chinese medicine composition of traumatic injury for one kind, it is characterized in that, be made up of the Chinese medicine of following weight portion: Herba Lycopodii 20-35 part, nine Ns of power 30-45 parts, Folium Isatidis 40-60 part, profit Caulis Fibraureae 70-90 part, Radix Flemingiae Philippinensis 30-50 part, Herb Gynostemmae Pentaphylli 70-90 part, short holder many 15-35 part, Folium Perillae 40-60 part, milk rattan 20-35 part, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 20-40 part, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15-35 part, three colored 50-70 parts, Ramulus et Folium Rhinacanthi nasuti 70-90 part, Herba Blumeae Balsamiferae 70-90 part, Herba Girardiniae Palmatae 30-50 part, Radix Kadsurae longipedunculatae 50-70 part, Mao Jingang 15-25 part, Ramulus Uncariae Cum Uncis 40-60 part, Rhizoma Smilacis Glabrae 15-30 part, optical axis Zhu Ye Betel 70-90 part.
2. treat the Chinese medicine composition of traumatic injury according to claim 1, it is characterized in that, be made up of the Chinese medicine of following weight portion: Herba Lycopodii 25 parts, nine Ns of power 35 parts, Folium Isatidis 50 parts, sharp Caulis Fibraureae 80 parts, Radix Flemingiae Philippinensis 40 parts, Herb Gynostemmae Pentaphylli 80 parts, many 25 parts of short holder, Folium Perillae 50 parts, 25 parts, milk rattan, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 30 parts, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 25 parts, three spend 60 parts, Ramulus et Folium Rhinacanthi nasuti 80 parts, Herba Blumeae Balsamiferae 80 parts, Herba Girardiniae Palmatae 40 parts, Radix Kadsurae longipedunculatae 60 parts, Mao Jingang 20 parts, Ramulus Uncariae Cum Uncis 50 parts, Rhizoma Smilacis Glabrae 25 parts, optical axis ramie leaf Betel 80 parts.
3. according to claim 1 or 2, treat the Chinese medicine composition of traumatic injury, it is characterized in that, described Chinese medicine composition makes any preparation pharmaceutically allowed.
4. treat the Chinese medicine composition of traumatic injury according to claim 3, it is characterized in that, described preparation is emplastrum, ointment, gel, liniment, tincture, medicated wine, liniment or spray.
5. the Chinese medicine composition for the treatment of traumatic injury as claimed in claim 1 makes a method for tincture, it is characterized in that, comprises the following steps:
(1) Chinese medicine is taken by following weight portion: Herba Lycopodii 20-35 part, nine Ns of power 30-45 parts, Folium Isatidis 40-60 part, profit Caulis Fibraureae 70-90 part, Radix Flemingiae Philippinensis 30-50 part, Herb Gynostemmae Pentaphylli 70-90 part, short holder many 15-35 part, Folium Perillae 40-60 part, milk rattan 20-35 part, Saurauia tristyla DC. var. oldhamii (Hemsl.) Finet & Gagncp. 20-40 part, Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 15-35 part, three colored 50-70 parts, Ramulus et Folium Rhinacanthi nasuti 70-90 part, Herba Blumeae Balsamiferae 70-90 part, Herba Girardiniae Palmatae 30-50 part, Radix Kadsurae longipedunculatae 50-70 part, Mao Jingang 15-25 part, Ramulus Uncariae Cum Uncis 40-60 part, Rhizoma Smilacis Glabrae 15-30 part, optical axis Zhu Ye Betel 70-90 part,
(2) more than, two Ten Herbs, are ground into coarse powder, use 60-90% ethanol as solvent, flood after 24-48 hour, with the speed of 1-3ml per minute slowly percolation, collect percolate, stir evenly, filter, to obtain final product.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105770664A (en) * | 2016-03-29 | 2016-07-20 | 新乡医学院三全学院 | Traditional Chinese medicine with functions of relieving swelling and pain for traumatic injury in movement and preparation method thereof |
| CN107115509A (en) * | 2017-06-22 | 2017-09-01 | 贵州省安顺市黔艺贝纺织有限公司 | A kind of external application Blumea balsamifera dissipates stasis of blood medicinal liquor |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105770664A (en) * | 2016-03-29 | 2016-07-20 | 新乡医学院三全学院 | Traditional Chinese medicine with functions of relieving swelling and pain for traumatic injury in movement and preparation method thereof |
| CN107115509A (en) * | 2017-06-22 | 2017-09-01 | 贵州省安顺市黔艺贝纺织有限公司 | A kind of external application Blumea balsamifera dissipates stasis of blood medicinal liquor |
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