CN104593208A - Living body male silkworm moth liquor and preparation method thereof - Google Patents

Living body male silkworm moth liquor and preparation method thereof Download PDF

Info

Publication number
CN104593208A
CN104593208A CN201510013017.5A CN201510013017A CN104593208A CN 104593208 A CN104593208 A CN 104593208A CN 201510013017 A CN201510013017 A CN 201510013017A CN 104593208 A CN104593208 A CN 104593208A
Authority
CN
China
Prior art keywords
male
parts
bombycis mori
live body
male bombycis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510013017.5A
Other languages
Chinese (zh)
Inventor
惠波年
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201510013017.5A priority Critical patent/CN104593208A/en
Publication of CN104593208A publication Critical patent/CN104593208A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G3/00Preparation of other alcoholic beverages
    • C12G3/04Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/64Insects, e.g. bees, wasps or fleas
    • A61K35/644Beeswax; Propolis; Royal jelly; Honey
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/46Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses living body male silkworm moth liquor and a preparation method thereof. The living body male silkworm moth liquor is prepared from the following raw materials: living body male silkworm moths, fresh mulberries, herba epimedii, wolfberries, red dates, cynomorium songaricum, eucommia ulmoides and native honey. The preparation method comprises the following steps: carrying out dephosphorizing coarse treatment; soaking; preparing liquor of Chinese medical herbs; filtering; mixing; mixing and blending; carrying out refined filtration; and filling after passed inspection. The invention provides the living body male silkworm moth liquor which can guarantee raw material supply and quality and is high in product active components and good in taste, and moreover, the liquor further has the functions of invigorating the kidney and strengthening Yang and replenishing essence and benefiting marrow.

Description

A kind of live body male silkworm moths spirit and preparation method thereof
Technical field
The present invention relates to Chinese medicine preparation and field of health care products, particularly a kind of live body male silkworm moths spirit and preparation method thereof.
Background technology
Male Bombycis mori is the male insect of silkworm, and also known as silkworm king in traditional Chinese medicine, late silkworm moth, belongs to " integration of drinking and medicinal herbs " insect, has the double effects of curing the disease with edible and healthy, is just considered as a kind of precious tonic than imperial family as far back as Tang and Song Dynasty time.
Male Bombycis mori composition is very complicated, and modern study also clear and definite major ingredient is: protein, lipid acid, biologically active substance, male hormone, molting hormone, neotonin, brain hormones, Regular Insulin, prostaglandin(PG), estradiol, cytochrome C etc.; In addition, also containing abundant vitamin B12, nicotinic acid, α-ecdyson in male Bombycis mori body, β-ecdyson, the various trace elements such as potassium, sodium, phosphorus, selenium, wherein the content of organoselenium is high, has fabulous effect to adjustment function of human body.
Male Bombycis mori is a kind of important pharmaceutical insects in the traditional Chinese medical science.Clinically be mainly used in therapeutic function illness, be recorded in the earliest " Mingyi Bielu " as Chinese medicine.Record according to Ming Dynasty's LI Shi-Zhen Compendium of Material Medica: " male silkworm king benefit vital essence, reinforcing yin essence road, joins tireless, also stops essence, establishing-Yang thing, stopping leak essence, hematuria etc." " silkworm moth property is excessive, goes out cocoon and namely reaches agreement, as withered be ".Silkworm moth is held sway over a region for " refreshing worm national treasure " in Compendium of Material Medica." Chinese medicine voluminous dictionary " carries: " male Bombycis mori liver-kidney tonifying, Yang strengthening and life essence tonifying.”
Male Bombycis mori makes health promoting wine with a long history, and traditional making method is after male Bombycis mori collection being returned, and after dryness in the sun, directly to soak be made for 15 to 20 days with more than 50 degree white wine according to the certain proportion of wine and male Bombycis mori.Its major drawbacks is:
1. male Bombycis mori raw material used: the mainly mating male Bombycis mori repeatedly eliminated of the seed station production of hybrid seeds, is in the state of a kind of sericulture there byproduct comprehensive utilization, male Bombycis mori quality and quantity are difficult to ensure, restriction mass-producing exploitation;
2. Feedstock treating: by male Bombycis mori by be exposed to the sun or the method for heat drying processes, to avoid the putrid and deteriorated of silkworm moth, in male Bombycis mori body, various active composition difficulty or ease keep;
3. desquamation cant method: cannot be departed from by the male Bombycis mori body surface palea of airing or heat drying, so unprocessed, directly use;
4. technical process: dry male Bombycis mori and white wine directly soak in proportion, the validity of product composition is restricted;
5. mouthfeel and effect: have dense male Bombycis mori stink, mouthfeel is poor;
In view of more than, need to be optimized from extraction process aspect the technique of male silkworm moths spirit.
Summary of the invention
Technical problem to be solved by this invention overcomes the deficiencies in the prior art, and provide a kind of raw material supplying and quality, live body male silkworm moths spirit that product active ingredient is high and mouthfeel is good of can ensureing, it also has kidney invigorating and YANG supporting, effect of essence-filling, marrow-benefitting simultaneously.
The object of the present invention is to provide a kind of live body male silkworm moths spirit, be made up of following weight proportioning: live body male Bombycis mori 20-30 part, fresh mulberries 10-20 part, Herba Epimedii 20-30 part, matrimony vine 5-15 part, red date 5-15 part, cynomorium songaricum 5-15 part, bark of eucommia 2-10 part, scoliid honey 0.2-1 part, more than 50 degree white wine 50-100 parts, less than 45 degree white wine 80-120 parts.
A kind of live body male silkworm moths spirit as above, wherein, live body male Bombycis mori 25 parts, fresh mulberries 15 parts, Herba Epimedii 25 parts, matrimony vine 10 parts, red date 10 parts, cynomorium songaricum 10 parts, the bark of eucommia 5 parts, scoliid honey 0.5 part, more than 50 degree white wine 50 parts, less than 45 degree white wine 100 parts.
A preparation method for live body male silkworm moths spirit, comprises the steps:
(1) live body dephosphorization hair process: the live body male Bombycis mori be up to the standards is carried out remove fine hair, removing foreign matter;
(2) soak: by the male Bombycis mori of step one gained with more than 50 degree white wine with 1: 1 ratio carry out one-level immersion 40-45 days; Male Bombycis mori less than the 45 degree white wine again one-level being soaked gained carry out secondary soak 40-45 days with the ratios of 4: 1; Male Bombycis mori stoste can be obtained;
(3) according to formulation weight part, fresh mulberries, Herba Epimedii, matrimony vine, red date, cynomorium songaricum, the bark of eucommia are carried out artificial separation, removed impurity, cutting, by the white wine lixiviate with more than 50 degree of the raw material that obtains; Obtain herbal medicine stoste;
(4) filter: male Bombycis mori stoste, herbal medicine stoste are filtered respectively;
(5) mix: the male Bombycis mori stoste of step 4 gained, herbal medicine stoste are carried out mix and blend in 1: 1 ratio;
(6) allotment is blent: blend adding auxiliary material in step 5 gained extracting solution;
(7) then step 6 gained male silkworm moths spirit is carried out cold-heat treatment, essence filter, carry out through after the assay was approved filling.
The preparation method of a kind of live body male silkworm moths spirit as above, wherein, male Bombycis mori described in described step one is the live body male Bombycis mori of non-mating.
The preparation method of a kind of live body male silkworm moths spirit as above, wherein, described male Bombycis mori is directly rubbed by hand, moth body palea is departed from, repeatedly rinses afterwards with clear water, until moth body palea is clean.
The preparation method of a kind of live body male silkworm moths spirit as above, wherein, auxiliary material described in described step 6 refers to scoliid honey.
Compared with prior art, the beneficial effect that the present invention produces is mainly reflected in:
1, this invention ensures that quantity and the quality of male Bombycis mori:
Tradition sericulture is owing to being subject to technical limitation, and male and female silkworm difficulty or ease separately, can only mix raising, so the exploitation to male Bombycis mori, the mainly male Bombycis mori inferior horn raw material of mating eliminated of the seed station production of hybrid seeds, not only of poor quality, the quantity of raw material sources is also extremely restricted.And be in the present invention, utilize genetic engineering technique, investigated autocratic male silkworm egg, and male silkworm egg is dealt into rural area raising, then male silk cocoon orientation is regained, after heating and moistening process, the silkworm moth that sprouts wings be male, namely carry out processing treatment (i.e. boy moth) without the need to mating, not only the quality of male Bombycis mori improves greatly, simultaneously the quantity of the male Bombycis mori number of animals raised that also can strengthen in rural area according to the need of production of enterprise, has ensured raw material supplying.
2, the process aspect of male Bombycis mori:
Male Bombycis mori is Insecta in zoological taxonomy, lepidopterous insects.Its body surface gathers a large amount of paleas, if do not process, after these paleas food is lower, to the respiratory system of people and lung organ very harmful, be traditional male Bombycis mori drying is directly processed unsolved problem afterwards.This technical study have developed the live body period after male Bombycis mori is sprouted wings, and carries out removing process to its body surface palea, and keeps male Bombycis mori to be after treatment still existing state, and then the technology of processing and utilization.Main method is: the live body male Bombycis mori produced through male silkworm technology of specially supporting, and directly rubs by hand, moth body palea is departed from, repeatedly rinses afterwards with clear water, until moth body palea is clean; Thus eliminate moth body objectionable impurities.
3, immersion treatment aspect:
The present invention carries out secondary immersion to live body male Bombycis mori:
One-level is soaked: by the live body male Bombycis mori after the process of desquamation hair, after removing death, tattered silkworm moth and the removal of impurity, select male Bombycis mori 50 degree of high quality liquors (moth: the wine) ratio that moth body is complete, body surface totally, is still in existing state and soak 40---45 days;
Secondary soaks: the male Bombycis mori soaking out by one-level is with 38, and---white wine (moth: the wine) ratio of 45 degree soaks 40---45 days, makes male silkworm moths spirit stoste after filtering.
Embodiment
Below by specific embodiment, the invention will be further described, but the invention is not restricted to following embodiment.
Embodiment 1:
Embodiments of the invention 1 are: get live body male Bombycis mori 20 parts, carry out the process of dephosphorization hair to it, then itself and more than 50 degree white wine 20 parts are carried out one-level with 1: 1 ratio soak 40 days; Again by itself and less than 45 degree white wine 80 parts with 4: 1 ratio carry out secondary and soak 40 days; Obtain male Bombycis mori stoste; By Herba Epimedii 20 parts, matrimony vine 5 parts, red date 5 parts, cynomorium songaricum 5 parts, the bark of eucommia 2 parts, the white wine lixiviate of scoliid honey 0.2 part of use more than 50 degree, obtains herbal medicine stoste; Male Bombycis mori stoste, herbal medicine stoste are stirred in 1: 1 ratio, allocates and blend, filter, to obtain final product.
Embodiment 2:
Embodiments of the invention 2 are: get live body male Bombycis mori 30 parts, carry out the process of dephosphorization hair to it, then itself and more than 50 degree white wine 30 parts are carried out one-level with 1: 1 ratio soak 45 days; Again by itself and less than 45 degree white wine 120 parts with 4: 1 ratio carry out secondary and soak 45 days; Obtain male Bombycis mori stoste; By Herba Epimedii 30 parts, matrimony vine 15 parts, red date 15 parts, cynomorium songaricum 15 parts, the bark of eucommia 10 parts, the white wine lixiviate of scoliid honey 1 part of use more than 50 degree, obtains herbal medicine stoste; Male Bombycis mori stoste, herbal medicine stoste are stirred in 1: 1 ratio, allocates and blend, filter, to obtain final product.
Embodiment 3:
Embodiments of the invention 3 are: get live body male Bombycis mori 25 parts, carry out the process of dephosphorization hair to it, then itself and more than 50 degree white wine 25 parts are carried out one-level with 1: 1 ratio soak 40 days; Again by itself and less than 45 degree white wine 100 parts with 4: 1 ratio carry out secondary and soak 40 days; Obtain male Bombycis mori stoste; By Herba Epimedii 25 parts, matrimony vine 10 parts, red date 10 parts, cynomorium songaricum 10 parts, the bark of eucommia 5 parts, the white wine lixiviate of scoliid honey 0.5 part of use more than 50 degree, obtains herbal medicine stoste; Male Bombycis mori stoste, herbal medicine stoste are stirred in 1: 1 ratio, allocates and blend, filter, to obtain final product.
In order to test assembled alcoholic drinks effect that live body male Bombycis mori is developed into, be convenient to experimentation on animals, we carry out dealcoholysis to live body male silkworm moths spirit and become oral liquid by cockscomb test, the test of rat sexual organ, the test of castration rabbit and deficiency of yang mouse test etc., confirm its related efficacy.
1, male silkworm moths spirit dealcoholysis oral liquid is tested the male function of chick
Choose under the brown chicken of the white Luo Man of squab health is placed in thermostatic control identical conditions and raise.Within 3 days, be divided into test and control group afterwards at random.Every dosage group 10, first numbers and weighs one by one, then gavage, every day 1 time, continuous 10 days, 20h after last administration is lethal by Animal Anesthesia with ether, with minor operation cutter in cockscomb root and scalp junction, along both sides stringer otch, the degree of depth of otch vertically arrives skull bone, the whole cockscomb of horizontal position clip, absorb otch blood with filter paper, put analytical balance and call its weight in wet base in the following text.The results are shown in Table 1:
Table 1 male silkworm moths spirit dealcoholysis oral liquid Andrin-like action chick hat experimental result
Table 2 male silkworm moths spirit dealcoholysis oral liquid-yanshenghubaoye male sample effect chick hat experimental result
t0.05=2.26t0.01=3.25
8.5ml/kg and 17ml/kg of male silkworm moths spirit dealcoholysis oral liquid with contrast physiological saline group and compare in chick cockscomb test that there were significant differences, as table 1 and male silkworm moths spirit dealcoholysis oral liquid two dosage groups and YANSHENG HUBAO YE two dosage group paired comparisons as can be seen from Table 2, heavy dose of group has significant difference, low dose group there was no significant difference, effect is similar, body weight all increases, and does not find untoward reaction.
2, male silkworm moths spirit dealcoholysis oral liquid is to the Andrin-like action of rat
Get 50 Adult male rats, under etherization excise bilateral testes, second day after operation is divided into 5 groups at random, often organize 10, gastric infusion, control group to physiological water, YANSHENG HUBAO YE height 1.5ml/100g and 0.75ml/100g.Male silkworm moths spirit dealcoholysis oral liquid height 3ml/100g and 1.5ml/100g two groups.Administration every day 1 time, continuous 7 days, after last administration, 2h put to death animal, weighs, takes seminal fluid capsule, prostate gland, weigh.Separately get 50 normal male rats and be divided into 5 groups at random, administration as stated above, every day 1 time, continuous 7 days, within 2 hours after not secondary administration, put to death animal, weigh, take seminal fluid capsule, prostate gland, testis weigh.The results are shown in Table 3.
Table 3 male silkworm moths spirit dealcoholysis oral liquid is on the impact of castrated rats seminal fluid capsule, weight of prostate
Male silkworm moths spirit dealcoholysis oral liquid and YANSHENG HUBAO YE all can make castrated rats seminal fluid capsule, weight of prostate increases as shown in table 3.The seminal fluid capsule of normal rat, prostate gland, testicular weight can be made as shown in table 4 higher than control group.YANSHENG HUBAO YE group also has effect same.
3, male silkworm moths spirit dealcoholysis oral liquid is on castration rabbit prostate gland---the impact of seminal vesicle weight
Get body weight 2 ~ 3kg male rabbit 15, excision both sides testis is divided into 3 groups at random, often organizes 5, raises with purified diet and Radix Dauci Sativae, Chinese cabbage.Postoperative mycillin preventing infection in 7 days every day gastric infusion once, first group is that blank group gives 10ml/kg physiological saline, second group 10ml/kg male silkworm moths spirit dealcoholysis oral liquid, continuous use 7 days, each thought-read electricity before and after medication, liver function, routine urinalysis, routine blood test 1 time, every death toll of day entry rabbit and the symptom of appearance.The results are shown in Table 4,5.
The oral castration rabbit prostate gland seminal vesicle weight experiment of surging of table 4 male silkworm moths spirit dealcoholysis, liver function routine urinalysis affects
Table 5 male silkworm moths spirit dealcoholysis oral liquid exempts from routine blood test impact to castration man
After male silkworm moths spirit dealcoholysis oral liquid gavages castration rabbit, all are normally as shown in table 4,5.Unchanged before and after electrocardiogram(ECG administration (figure slightly), routine blood test, routine urinalysis, liver function indices are without significant difference, and prostate gland---seminal vesicle has increasing trend.In process of the test, dead 1 of control animals, heavy dose of group is only dead, within 1 day all after surgery, dies.The cause of death likely postoperative group do rhzomorph and cause, all are normal for residue animal.
4, male silkworm moths spirit dealcoholysis oral liquid is to the effect of deficiency of yang mouse. and get male mice 30, be divided into 3 groups at random.Deficiency of yang group is noted with hydrocortisone 0.4mg/ stock, fills with, every day 1 time, continuous 7 days with physiological saline 0.3ml/10g simultaneously.Deficiency of yang treatment group replaces physiological saline with male silkworm moths spirit dealcoholysis oral liquid 0.3ml/10g, and other is with deficiency of yang group; Control group not administration, only with normal saline intramuscular injection gavage.The results are shown in Table 6
Table 6 male silkworm moths spirit dealcoholysis oral liquid exempts from routine blood test impact to castration man
To in deficiency of yang mouse test, deficiency of yang control group occurs that obvious adrenal cortex exhausts phenomenon, and show as hogback and move less, hair is rough, and body weight obviously alleviates, and minority mouse two does not open, similar to the YANG asthenia disease of the mankind.Treatment group mouse symptom is lighter than deficiency of yang control group, and weight loss is not obvious.Result shows that male silkworm moths spirit dealcoholysis oral liquid has treatment regulating effect to YANG asthenia disease mouse.
From young cockscomb test, the test of rat male organs, the test of castration rabbit and deficiency of yang mouse test, can show that male silkworm moths spirit dealcoholysis oral liquid has the conclusion of male hormone effect, have no adverse reaction.Male Bombycis mori in its prescription, Herba Epimedii, matrimony vine, cynomorium songaricum etc. all have kidney invigorating and YANG supporting effect.Male Bombycis mori is containing testosterone, estradiol and 18 seed amino acids, three kinds of insect hormone neotonins, brain hormones and molting hormones.
Above-mentioned experiment confirms live body male silkworm moths spirit of the present invention, and it has kidney invigorating and YANG supporting, effect of essence-filling, marrow-benefitting.

Claims (6)

1. a live body male silkworm moths spirit, is characterized in that: be made up of following weight proportioning:
Live body male Bombycis mori 20-30 part, fresh mulberries 10-20 part, Herba Epimedii 20-30 part, matrimony vine 5-15 part, red date 5-15 part, cynomorium songaricum 5-15 part, bark of eucommia 2-10 part, scoliid honey 0.2-1 part, more than 50 degree white wine 50-100 parts, less than 45 degree white wine 80-120 parts.
2. a kind of live body male silkworm moths spirit according to claim 1, is characterized in that,
Live body male Bombycis mori 25 parts, fresh mulberries 15 parts, Herba Epimedii 25 parts, matrimony vine 10 parts, red date 10 parts, cynomorium songaricum 10 parts, the bark of eucommia 5 parts, scoliid honey 0.5 part, more than 50 degree white wine 50 parts, less than 45 degree white wine 100 parts.
3. a preparation method for live body male silkworm moths spirit, is characterized in that: comprise the steps:
(1) live body dephosphorization hair process: the live body male Bombycis mori be up to the standards is carried out remove fine hair, removing foreign matter;
(2) soak: by the male Bombycis mori of step one gained with more than 50 degree white wine with 1: 1 ratio carry out one-level immersion 40-45 days; Male Bombycis mori less than the 45 degree white wine again one-level being soaked gained carry out secondary soak 40-45 days with the ratios of 4: 1; Male Bombycis mori stoste can be obtained;
(3) according to formulation weight part, fresh mulberries, Herba Epimedii, matrimony vine, red date, cynomorium songaricum, the bark of eucommia are carried out artificial separation, removed impurity, cutting, by the white wine lixiviate with more than 50 degree of the raw material that obtains; Obtain herbal medicine stoste;
(4) filter: male Bombycis mori stoste, herbal medicine stoste are filtered respectively;
(5) mix: the male Bombycis mori stoste of step 4 gained, herbal medicine stoste are carried out mix and blend in 1: 1 ratio;
(6) allotment is blent: blend adding auxiliary material in step 5 gained extracting solution;
(7) then step 6 gained male silkworm moths spirit is carried out cold-heat treatment, essence filter, carry out through after the assay was approved filling.
4. the preparation method of a kind of live body male silkworm moths spirit according to claim 3, is characterized in that:
Male Bombycis mori described in described step one is the live body male Bombycis mori of non-mating.
5. the preparation method of a kind of live body male silkworm moths spirit according to claim 4, is characterized in that:
Described male Bombycis mori is directly rubbed by hand, moth body palea is departed from, repeatedly rinses afterwards with clear water, until moth body palea is clean.
6. the preparation method of a kind of live body male silkworm moths spirit according to claim 3, is characterized in that:
Auxiliary material described in described step 6 refers to scoliid honey.
CN201510013017.5A 2015-01-12 2015-01-12 Living body male silkworm moth liquor and preparation method thereof Pending CN104593208A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201510013017.5A CN104593208A (en) 2015-01-12 2015-01-12 Living body male silkworm moth liquor and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201510013017.5A CN104593208A (en) 2015-01-12 2015-01-12 Living body male silkworm moth liquor and preparation method thereof

Publications (1)

Publication Number Publication Date
CN104593208A true CN104593208A (en) 2015-05-06

Family

ID=53119267

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510013017.5A Pending CN104593208A (en) 2015-01-12 2015-01-12 Living body male silkworm moth liquor and preparation method thereof

Country Status (1)

Country Link
CN (1) CN104593208A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105349355A (en) * 2015-09-29 2016-02-24 赵春山 AOB silkworm moth Phellinus igniarius healthcare wine and preparation process
CN108192791A (en) * 2018-03-12 2018-06-22 大连军门保健食品有限公司 A kind of male silk moth health health preserving wine and preparation method thereof
CN108220098A (en) * 2018-03-12 2018-06-29 大连军门保健食品有限公司 A kind of live body male silk moth health preserving wine and preparation method thereof
CN109294788A (en) * 2018-12-07 2019-02-01 中法合营王朝葡萄酿酒有限公司 A kind of aromatized wine and its blending process
CN112779116A (en) * 2020-12-28 2021-05-11 辽宁中天蚕业科技有限公司 Brewing process and preparation method of health-preserving silkworm moth wine
CN116333843A (en) * 2023-04-04 2023-06-27 四川极美生命高科技有限公司 Sleep-aiding kidney-tonifying compound wine and preparation method thereof

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1214918A (en) * 1997-10-20 1999-04-28 吴戈 Shengli reinforcing kidney liquid
CN1857559A (en) * 2006-03-27 2006-11-08 承德颈复康药业集团有限公司 Impotence treating medicine and its preparing method
CN101007127A (en) * 2007-01-30 2007-08-01 冯井胜 A compound male silk moth health wine for male and processing method
CN101664499A (en) * 2009-09-17 2010-03-10 赤峰丹龙药业有限公司 Xianhuo kidney tonifying mixture
CN101904944A (en) * 2010-07-16 2010-12-08 韩乐平 Male silkworm health care wine and preparation method thereof
CN102477387A (en) * 2010-11-29 2012-05-30 丹东桐济天然保健品有限责任公司 Magical insect health wine and its preparation method
CN102475831A (en) * 2010-11-29 2012-05-30 丹东桐济天然保健品有限责任公司 Bombyx health care product and preparation method for same
CN102533519A (en) * 2012-03-02 2012-07-04 辽宁柞蚕丝绸科学研究院有限责任公司 Method for preparing male silkworm moth spirits
CN102851188A (en) * 2012-08-28 2013-01-02 江苏恒顺醋业股份有限公司 Traditional Chinese medicine tonic wine for enhancing immunity and preparation method thereof
CN103525632A (en) * 2013-09-17 2014-01-22 李前进 Health-care wine and preparation method

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1214918A (en) * 1997-10-20 1999-04-28 吴戈 Shengli reinforcing kidney liquid
CN1857559A (en) * 2006-03-27 2006-11-08 承德颈复康药业集团有限公司 Impotence treating medicine and its preparing method
CN101007127A (en) * 2007-01-30 2007-08-01 冯井胜 A compound male silk moth health wine for male and processing method
CN101664499A (en) * 2009-09-17 2010-03-10 赤峰丹龙药业有限公司 Xianhuo kidney tonifying mixture
CN101904944A (en) * 2010-07-16 2010-12-08 韩乐平 Male silkworm health care wine and preparation method thereof
CN102477387A (en) * 2010-11-29 2012-05-30 丹东桐济天然保健品有限责任公司 Magical insect health wine and its preparation method
CN102475831A (en) * 2010-11-29 2012-05-30 丹东桐济天然保健品有限责任公司 Bombyx health care product and preparation method for same
CN102533519A (en) * 2012-03-02 2012-07-04 辽宁柞蚕丝绸科学研究院有限责任公司 Method for preparing male silkworm moth spirits
CN102851188A (en) * 2012-08-28 2013-01-02 江苏恒顺醋业股份有限公司 Traditional Chinese medicine tonic wine for enhancing immunity and preparation method thereof
CN103525632A (en) * 2013-09-17 2014-01-22 李前进 Health-care wine and preparation method

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
任培华 等: "雄蚕蛾酒工厂化生产技术研究", 《四川蚕业》 *
张晓霞: "交泰酒的研制", 《酿酒》 *
郭玉清: "蚕蛾酒的制造", 《专业户》 *
高树梅: "工厂化生产雄蚕蛾酒的加工工艺研究", 《安徽农业科学》 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105349355A (en) * 2015-09-29 2016-02-24 赵春山 AOB silkworm moth Phellinus igniarius healthcare wine and preparation process
CN108192791A (en) * 2018-03-12 2018-06-22 大连军门保健食品有限公司 A kind of male silk moth health health preserving wine and preparation method thereof
CN108220098A (en) * 2018-03-12 2018-06-29 大连军门保健食品有限公司 A kind of live body male silk moth health preserving wine and preparation method thereof
CN109294788A (en) * 2018-12-07 2019-02-01 中法合营王朝葡萄酿酒有限公司 A kind of aromatized wine and its blending process
CN109294788B (en) * 2018-12-07 2022-03-11 中法合营王朝葡萄酿酒有限公司 Flavored wine and blending process thereof
CN112779116A (en) * 2020-12-28 2021-05-11 辽宁中天蚕业科技有限公司 Brewing process and preparation method of health-preserving silkworm moth wine
CN116333843A (en) * 2023-04-04 2023-06-27 四川极美生命高科技有限公司 Sleep-aiding kidney-tonifying compound wine and preparation method thereof

Similar Documents

Publication Publication Date Title
CN104593208A (en) Living body male silkworm moth liquor and preparation method thereof
CN103505385B (en) Herba Ecliptae hair color nutrition shampoo, hair color Ying Yang treatment wax and hair color nutritional solution dew
CN113455651A (en) A preparation containing stem cell extractive solution for improving metabolism and immunity and improving sub-health
CN101366927B (en) Honey gastrodia tuber plaster
CN102229877B (en) Brewing method for pine pollen wine
CN110477397B (en) Method for preparing dendrobium flower extracting solution and application thereof
CN116392509A (en) Method for inducing cow to form bezoar
RU2441660C1 (en) Method of treatment of subclinical mastitis in lactating cows
KR100902406B1 (en) Feed for ell
Karimi et al. The effects of artichoke aqueous extract on the growth performance, intestinal morphology, and blood metabolites in broiler chickens
KR20070025342A (en) Poultry egg having function to promote secretion of insulin and method for producing the same
CN106858067A (en) Livestock and poultry nonreactive growth promotion compound preparation and its production and use
CN106804902A (en) A kind of feed addictive for improving cow protein matter
CN103463628B (en) A kind ofly to be used for the treatment of or the pharmaceutical composition of prophylactic treatment senile dementia and preparation thereof
RU2700626C2 (en) Method for increasing quail productivity
CN1176697C (en) Antisenility medicine composition and its prepn
CN110973399A (en) Feed additive for improving physique and immunity of poultry and preparation method thereof
CN108853480A (en) Hair growth composition, preparation method and applications
CN110477208A (en) A kind of broiler fodder improving chicken meat quality
CN110339315A (en) A kind of mongolian veterinary drug feed addictive and preparation method thereof for promoting ewe ovulation to produce twin lamb(s)
CN108835454A (en) A kind of feed addictive of layer chicken and preparation method thereof
CN109497300A (en) A kind of feed addictive reducing goat smell of mutton
CN109248176A (en) A kind of artificial pangolin compound powder
CN115918783B (en) Feed additive for improving egg laying performance of laying hens and preparation method thereof
CN106509139A (en) Health-care milk tablets capable of delaying senescence

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20150506