CN104587311A - Spleen-invigorating and dampness-eliminating traditional Chinese medicine extract and preparation method and application thereof as well as spleen-invigorating and dampness-eliminating cream - Google Patents

Spleen-invigorating and dampness-eliminating traditional Chinese medicine extract and preparation method and application thereof as well as spleen-invigorating and dampness-eliminating cream Download PDF

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CN104587311A
CN104587311A CN201510066491.4A CN201510066491A CN104587311A CN 104587311 A CN104587311 A CN 104587311A CN 201510066491 A CN201510066491 A CN 201510066491A CN 104587311 A CN104587311 A CN 104587311A
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spleen
parts
chinese medicine
medicine extract
invigorating
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CN104587311B (en
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周立
卢其福
黄喜梅
随晶晶
叶雪兰
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Guangzhou Baiyunshan Pan'gaoshou Pharmaceutical Co Ltd
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Guangzhou Baiyunshan Pan'gaoshou Pharmaceutical Co Ltd
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Abstract

The invention discloses a spleen-invigorating and dampness-eliminating traditional Chinese medicine extract and a preparation method and an application thereof as well as a spleen-invigorating and dampness-eliminating cream. The spleen-invigorating and dampness-eliminating Chinese medicine extract is prepared by extracting the following raw materials in parts by weight: 3 to 4 parts of poria, 4 to 5 parts of yams, 3 parts of coix seeds, 3 to 4 parts of malt, and 1 part of tangerine peels. The poria, yams, coix seeds, malt, and tangerine peels are added to achieve the efficacies of invigorating the spleen and strengthening the middle energizer, and benefiting Qi and eliminating dampness, and can be used for alleviating the loss of appetite, abdominal distension, loose stools, dyspepsia, fatigue and weakness and other symptoms caused by the excessive dampness due to deficiency in spleen. The traditional Chinese medicinal materials in a formula are mutually synergized in property, flavor and function aspects, and the traditional Chinese medicine extract can be taken by people having excessive dampness due to deficiency in spleen.

Description

Chinese medicine extract that spleen invigorating is dried and preparation method thereof, application and spleen invigorating are dried cream
Technical field
The present invention relates to field of food, particularly Chinese medicine extract of drying of a kind of spleen invigorating and preparation method thereof, application and spleen invigorating are dried cream.
Background technology
Cream side, also known as soft extract, soft extracts, be that the prepared slices of Chinese crude drugs decoct by one repeatedly, remove slag extracting juice, through evaporation and concentration, the semifluid shape dosage form that sugaring or Mel etc. are made.Cream side is mainly used in nourishing and health preserving and medical treatment chronic disease.In traditional sense, the effect of cream side comprises the dual function of " rescue and partially cure a disease ".Due to illness cause void, because of void cause a disease, available cream side; Chronic, intractable, consumptive illness, also can take good care of with cream side, so cream side is different from other tonic benefit sides, it has invigorating middle warmer residence and controls, and controls middle residence and mends, mend the feature controlling combination.
Along with the raising of social economy, Sciences Economics and living standards of the people, subhealth state more and more enters the visual field of people.The investigation display of World Health Organization (WHO): in crowd, the people of more than 75% is in sub-health state.Subhealth state is main corresponding " asthenia " disease in theory of Chinese medical science, and the Therapeutic Principle of asthenia is based on tonification, and the traditional Chinese medical science is thought, the spleen being the foundation of acquired constitution, is source of generating QI and blood, and the strong fortune of taste, the vital organs of the human body, extremity bones of the body collectively can be nourished.If insufficiency of the spleen leading to overabundance of dampness, then there will be inappetence, abdominal distention, loose stool, dyspepsia, the tired symptom such as weak of god.
It is one of important method improving subhealth state that cream side takes good care of.Do not have the special cream side for insufficiency of the spleen leading to overabundance of dampness body constitution in the market, on market, common cream side such as primordial QI reinforcing cream primary efficacy is that kidney tonifying is enriched blood, and YANG invigorating QI invigorating then emphasized by Radix Ginseng, Cornu Cervi Pantotrichum and so on tonic, is all not suitable for insufficiency of the spleen leading to overabundance of dampness body constitution crowd and takes.By distinguishing body constitution, taking Chinese herbal ointment formula targetedly, can equilibrium between yin and yang be reached, the object that diseases prevention gets rid of illness.Therefore, the Chinese herbal ointment formula providing a kind of insufficiency of the spleen leading to overabundance of dampness body constitution crowd to be also suitable for is necessary.
Summary of the invention
Based on this, be necessary for the problems referred to above, provide a kind of and be applicable to Chinese medicine extract of insufficiency of the spleen leading to overabundance of dampness body constitution crowd and preparation method thereof, application and spleen invigorating and dry cream.
The concrete technical scheme solved the problems of the technologies described above is as follows:
The Chinese medicine extract that spleen invigorating is dried, it is extracted by the raw material of following weight portion and is prepared from: 3 ~ 4 parts, Poria, Rhizoma Dioscoreae 4 ~ 5 parts, Semen Coicis 3 parts, 3 ~ 4 parts, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 1 part.
Wherein in some embodiments, it is extracted by the raw material of following weight portion and is prepared from: 3 parts, Poria, Rhizoma Dioscoreae 5 parts, Semen Coicis 3 parts, 3 parts, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 1 part.
The preparation method of the Chinese medicine extract that the present invention also provides above-mentioned spleen invigorating to dry, comprises the following steps:
(1) take raw material according to said ratio, described raw material is Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae;
(2) decoct with water twice, merge twice decoction liquor, concentrating under reduced pressure, filter pressing, at continuing to be concentrated into 80 DEG C, relative density is 1.12 ± 0.02, to obtain final product.
Wherein in some embodiments, comprise the following steps:
(1) take raw material according to said ratio, described raw material is Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae;
(2) decoct with water twice, first time decocts and adds described raw material 8-12 times water gaging, decocts 1-3 hour, obtain decoction liquor 1 from medicinal liquid boiling; Second time decocts and adds described raw material 8-10 times water gaging, decocts 0.5-2 hour, obtain decoction liquor 2 from medicinal liquid boiling; Merge twice decoction liquor, concentrating under reduced pressure, filter pressing, at continuing to be concentrated into 80 DEG C, relative density is 1.12 ± 0.02, to obtain final product.
The application that the present invention also provides above-mentioned Chinese medicine extract to dry in preparation in preparation spleen invigorating.
The present invention also provides a kind of spleen invigorating to dry cream, and its active component is the Chinese medicine extract that above-mentioned spleen invigorating is dried.
Wherein in some embodiments, its Chinese medicine extract 20 ~ 30wt% dried primarily of above-mentioned spleen invigorating, white sugar 25 ~ 35wt%, glucose syrup 40 ~ 50wt% is prepared from.
The Chinese medicine extract that spleen invigorating of the present invention is dried and the spleen invigorating pharmacological property of each component in the theory of Chinese medical science of cream and said composition that dries is as follows:
Poria is medicine-food two-purpose medical material, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, light, and property is put down.GUIXIN, spleen, kidney channel.Energy spleen invigorating, inducing diuresis to remove edema, eliminating dampness by diuresis, mind calming.For insufficiency of the spleen lack of appetite, have loose bowels in loose stool, edema oliguria, malaise.
Rhizoma Dioscoreae is the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, and property is put down.Return spleen, lung, kidney channel.Energy spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney.
Semen Coicis is the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, light, cool in nature.Return spleen, stomach, lung meridian.Energy spleen invigorating eliminating dampness by diuresis, inducing diuresis to remove edema, eliminating impediment, clearing away heat and discharging pus.For diarrhea due to hypofunction of the spleen, edema, dysuria, arthralgia chiefly caused by damp pathogen contracture, lung abscess, acute appendicitis.
Fructus Hordei Germinatus is the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", sweet in the mouth, and property is put down.Return spleen, stomach, Liver Channel.Energy promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite, galactopoiesis relieving distension.Do not disappear for food stagnation, abdominal distention, insufficiency of the spleen lack of appetite, milk smoulders, hypochondriac pain due to stagnation of liverQI, stomachache due to hyperactive liver-QI attacking the stomach.
Pericarpium Citri Reticulatae is the plant of medicine-food two-purpose, records in 2010 editions " Chinese Pharmacopoeias ", acrid in the mouth, hardship, warm in nature.Return spleen, lung meridian.Energy regulating qi-flowing for strengthening spleen, drying dampness to eliminate phlegm.For distension and fullness in the abdomen, lack of appetite and vomiting, cough with copious phlegm.
White sugar sweet in the mouth, property is put down, nontoxic.Enter spleen, lung meridian.Energy nourishing YIN and moistening the lung, and middle strengthening the spleen, promoting the production of body fluid to quench thirst, throat, relieves the effect of alcohol.For insufficiency of the spleen stomachache.
The present invention reaches spleen invigorating invigorating middle warmer by interpolation Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae, the merit of QI invigorating removing dampness, can alleviate caused by insufficiency of the spleen leading to overabundance of dampness inappetence, abdominal distention, loose stool, dyspepsia, the tired symptom such as weak of god, above-mentioned Chinese crude drug is mutually worked in coordination with in nature,taste and action, Poria replenishing QI to invigorate the spleen in side, compatibility Rhizoma Dioscoreae is to help Poria invigorating the spleen and benefiting QI, compatibility Semen Coicis dries to help Poria spleen invigorating, compatibility Fructus Hordei Germinatus is to help Poria promoting qi circulation, resolving food retention, more use Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, regulating fluid apssage, medicine carrying is up.Full side's enriching spleen-QI, dry turbid, circulation of qi promoting is stagnant, and temper spleen is transported, and turbid damp must go, and all diseases are from removing.The present invention can take for strong empty wet Sheng type body constitution crowd.
The present invention compared to the advantage of prior art and beneficial effect is:
(1) Poria selected by the present invention, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae are the plant of integration of edible and medicinal herbs, and source is sufficient, edible with a long history, without any toxicity; Inventor team, according to the characteristic of above-mentioned raw materials and conspiracy relation each other, relies on the experience that accumulates all the year round and a large amount of experiments and contrast test to draw proportioning between best raw material, to obtain better effect;
(2) the present invention has effect that spleen invigorating is dried, for nurse one's health caused by insufficiency of the spleen leading to overabundance of dampness inappetence, abdominal distention, loose stool, dyspepsia, god is tired weak etc., is suitable for long-term taking.
Detailed description of the invention
Raw materials usedly in embodiment be commercially available convenient source.
Below with reference to specific embodiment, the present invention will be further described.
Embodiment 1
The dry raw material of cream of spleen invigorating described in the present embodiment is as follows:
The Chinese medicine extract that spleen invigorating is dried: 252 grams (25.2wt%)
Be specially the extract of Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus and Pericarpium Citri Reticulatae
Adjuvant:
White sugar (sucrose) 320 grams (32wt%)
Glucose syrup 428 grams (42.8wt%)
Spleen invigorating described in the present embodiment is dried being prepared as follows of cream:
One, the spleen invigorating preparation of Chinese medicine extract of drying:
(1) claim 45 grams, Poria, Rhizoma Dioscoreae 75 grams, Semen Coicis 45 grams, 45 grams, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 15 grams, decoct secondary, first time adds drinking water 2L, and timing from medicinal liquid boiling, decocts 3 hours; Second time adds drinking water 1.8L, and timing from medicinal liquid boiling, decocts 1.5 hours; Merge twice water extraction decoction liquor, be evaporated to 600 milliliters (water volume with medical material weight 2.67 times), filter pressing, continue to be concentrated into same medical material weight water volume, about 225 milliliters, relative density is 1.12 ± 0.02 (80 DEG C), about 252 grams.
Two, the preparation of cream side:
(1) cream refining: get white sugar (sucrose), add suitable quantity of water, dissolve, filter, the Chinese medicine extract (Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae) that dries of clear and bright syrup and above-mentioned spleen invigorating merges refining 6 ~ 8 hours, obtain the clear paste that relative density is 1.20 ~ 1.37 (80 DEG C), for subsequent use;
(2) finished product: get above-mentioned clear paste and add glucose syrup and stir, boil, be cooled to 60 ~ 70 DEG C, fill and get final product.
Embodiment 2
The dry raw material of cream of spleen invigorating described in the present embodiment is as follows:
The Chinese medicine extract that spleen invigorating is dried: 200 grams (20wt%)
Be specially the extract of Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus and Pericarpium Citri Reticulatae
Adjuvant:
White sugar (sucrose) 320 grams (32wt%)
Glucose syrup 480 grams (48wt%)
The dry preparation of cream of spleen invigorating described in the present embodiment is identical with embodiment 1, and the Chinese medicine extract that wherein spleen invigorating is dried is extracted by the raw material of following weight and is prepared from: 3 parts, Poria, Rhizoma Dioscoreae 5 parts, Semen Coicis 3 parts, 3 parts, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 1 part.
Embodiment 3
The dry raw material of cream of spleen invigorating described in the present embodiment is as follows:
The Chinese medicine extract that spleen invigorating is dried: 300 grams (30wt%)
Be specially the extract of Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus and Pericarpium Citri Reticulatae
Adjuvant:
White sugar (sucrose) 300 grams (30wt%)
Glucose syrup 400 grams (40wt%)
The dry preparation of cream of spleen invigorating described in the present embodiment is identical with embodiment 1, and the Chinese medicine extract that wherein spleen invigorating is dried is extracted by the raw material of following weight and is prepared from: 3 parts, Poria, Rhizoma Dioscoreae 5 parts, Semen Coicis 3 parts, 3 parts, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 1 part.
Comparative example 1
Comparative example 1 is a kind of Chinese herbal ointment formula, and in cream side, each component, content and preparation method are substantially the same manner as Example 1, and difference is: it is not containing the Chinese medicine extract in embodiment 1.
Comparative example 2
Comparative example 2 is a kind of Chinese herbal ointment formula, and in cream side, each component, content and preparation method are substantially the same manner as Example 1, and difference is: lack Poria in its Chinese medicine extract.
Comparative example 3
Comparative example 3 is a kind of Chinese herbal ointment formula, and in cream side, each component, content and preparation method are substantially the same manner as Example 1, and difference is: increase Fructus Crataegi 30 grams in its Chinese medicine extract.
Comparative example 4
Comparative example 4 is a kind of Chinese herbal ointment formula, in cream side, each component, content and preparation method are substantially the same manner as Example 1, and difference is: in its Chinese medicine extract, the proportioning of each formula is: 45 grams, Poria, Rhizoma Dioscoreae 90 grams, Semen Coicis 45 grams, 45 grams, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 30 grams; Cream side's raw material is:
Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae extract 285 grams (28.5wt%)
White sugar (sucrose) 300 grams (30wt%)
Glucose syrup 415 grams (41.5wt%)
Embodiment 4: edible test:
Experimental subject: mainly for inappetence, abdominal distention, loose stool, dyspepsia, tired weak person 75 example of god, is divided into A, B, C, D, E five groups, often organizes 15 people.
A group: take Chinese herbal ointment formula described in the embodiment of the present invention 1, each serving with 15 grams, takes 2 every day, experiment results proved, after taking five days, 11 people represent inappetence, abdominal distention, loose stool, dyspepsia, the tired symptom such as weak of god alleviates, and 4 people represent DeGrain; After taking two weeks continuously, 13 people represent inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god obviously alleviates, and 1 people represents that symptom alleviates, and 1 people represents DeGrain.
B group: the cream side of taking comparative example 1, each serving with 15 grams, takes 2 every day, experiment results proved, and after taking five days, 1 people represents inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god alleviates, and 14 people represent DeGrain; After taking two weeks continuously, 2 people represent inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god alleviates, and 13 people represent DeGrain.
C group: the cream side of taking comparative example 2, each serving with 15 grams, takes 2 every day, experiment results proved, and after taking five days, 6 people represent inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god alleviates, and 9 people represent DeGrain; After taking two weeks continuously, 7 people represent inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god alleviates, and 8 people represent DeGrain.
D group: the cream side of taking comparative example 3, each serving with 15 grams, takes 2 every day, experiment results proved, and after taking five days, 8 people represent inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god alleviates, and 7 people represent DeGrain; After taking two weeks continuously, 9 people represent inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god alleviates, and 6 people represent DeGrain.
E group: the cream side of taking comparative example 4, each serving with 15 grams, takes 2 every day, experiment results proved, and after taking five days, 9 people represent inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god alleviates, and 6 people represent DeGrain; After taking two weeks continuously, 11 people represent inappetence, abdominal distention, loose stool, dyspepsia, and the tired symptom such as weak of god alleviates, and 4 people represent DeGrain.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.

Claims (7)

1. the Chinese medicine extract that dries of spleen invigorating, is characterized in that, it is extracted by the raw material of following weight portion and is prepared from: 3 ~ 4 parts, Poria, Rhizoma Dioscoreae 4 ~ 5 parts, Semen Coicis 3 parts, 3 ~ 4 parts, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 1 part.
2. the Chinese medicine extract that dries of spleen invigorating according to claim 1, is characterized in that, it is extracted by the raw material of following weight portion and is prepared from: 3 parts, Poria, Rhizoma Dioscoreae 5 parts, Semen Coicis 3 parts, 3 parts, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae 1 part.
3. a preparation method for the Chinese medicine extract that the spleen invigorating described in claim 1 or 2 is dried, is characterized in that, comprise the following steps:
(1) take raw material according to the proportioning of claim 1 or 2, described raw material is Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae;
(2) decoct with water twice, merge twice decoction liquor, concentrating under reduced pressure, filter pressing, at continuing to be concentrated into 80 DEG C, relative density is 1.12 ± 0.02, to obtain final product.
4. the spleen invigorating according to claim 3 preparation method of Chinese medicine extract of drying, is characterized in that, comprise the following steps:
(1) take raw material according to the proportioning of claim 1 or 2, described raw material is Poria, Rhizoma Dioscoreae, Semen Coicis, Fructus Hordei Germinatus, Pericarpium Citri Reticulatae;
(2) decoct with water twice, first time decocts and adds described raw material 8-12 times water gaging, decocts 1-3 hour, obtain decoction liquor 1 from medicinal liquid boiling; Second time decocts and adds described raw material 8-10 times water gaging, decocts 0.5-2 hour, obtain decoction liquor 2 from medicinal liquid boiling; Merge twice decoction liquor, concentrating under reduced pressure, filter pressing, at continuing to be concentrated into 80 DEG C, relative density is 1.12 ± 0.02, to obtain final product.
5. Chinese medicine extract according to claim 1 and 2 is in the preparation spleen invigorating application of drying in preparation.
6. spleen invigorating is dried a cream, it is characterized in that, the Chinese medicine extract that its active component dries for the spleen invigorating described in claim 1 or 2.
7. a kind of spleen invigorating according to claim 6 is dried cream, and it is characterized in that, its Chinese medicine extract 20 ~ 30wt% dried primarily of spleen invigorating as claimed in claim 1 or 2, white sugar 25 ~ 35wt%, glucose syrup 40 ~ 50wt% is prepared from.
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CN105596900A (en) * 2015-12-31 2016-05-25 毛春梅 Traditional Chinese medicine composition for treating functional dyspepsia
CN106266762A (en) * 2016-08-29 2017-01-04 董占斌 A kind of strengthening spleen, tonifying kidney damp eliminating prescription
CN106262914A (en) * 2016-09-22 2017-01-04 广西南宁乐蕊生物科技有限责任公司 A kind of damp eliminating nutritive powder
CN106942744A (en) * 2017-03-31 2017-07-14 洛阳领恩生物科技有限公司 Ginseng poria health products and its production method
CN110123979A (en) * 2018-02-08 2019-08-16 广州白云山潘高寿药业股份有限公司 The Chinese medicine composition of clearing damp resolving sputum, Chinese materia medica preparation and preparation method thereof
CN110123979B (en) * 2018-02-08 2021-08-06 广州白云山潘高寿药业股份有限公司 Traditional Chinese medicine composition for eliminating dampness and reducing phlegm, traditional Chinese medicine preparation and preparation method thereof
CN109287919A (en) * 2018-08-20 2019-02-01 广州初品信息科技有限公司 A kind of formula and preparation method of red bean adlay draft cream
CN116076719A (en) * 2021-11-02 2023-05-09 四川省中医药科学院中医研究所 Spleen-invigorating and lung-tonifying composition
CN113881537A (en) * 2021-11-04 2022-01-04 云南滇药医药健康产业有限公司 Brewing method of health-care white spirit

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