CN104586979A

CN104586979A - Cough-relieving oral liquid and preparation method thereof

Info

Publication number: CN104586979A
Application number: CN201510027818.7A
Authority: CN
Inventors: 郭雪峰
Original assignee: Tarim University
Current assignee: Tarim University
Priority date: 2015-01-17
Filing date: 2015-01-17
Publication date: 2015-05-06

Abstract

The invention discloses a cough-relieving oral liquid and a preparation method thereof, relating to the field of a medicament formula. The cough-relieving oral liquid comprises the following raw materials in percentage by mass: 10-20 % of radix glycyrrhizae, 10-20 % of radix platycodonis, 10-20 % of cornu saigae tataricae, 20-30 % of radix bupleuri and 20-30 % of folium eriobotryae. The preparation method comprises the following steps: 1, mixing medicinal materials with water according to the weight ratio of (1:1)-(1:50), decocting at the temperature of 50-100 DEG C until the solution takes up 1-100% of weight of the original medicinal materials; 2, adding the solution prepared in the step 1 into 1-100% of hippophae rhamnoides juice and then mixing with 1-100% of grain brewed mature vinegar; and 3, storing the solution prepared in the step 2 at the set temperature ranging from 0 to 20DEG C. The cough-relieving oral liquid is used for clearing heat and freeing lung, relieving asthma and relieving sore throat, and can be used for treating dieseases such as cough, trachitis, emphysema and asthma caused by heat cleaning from cold.

Description

One has cough stopping oral liquor and preparation method thereof

Technical field

The present invention relates to pharmaceutical formulation field, be specifically related to one and there is cough stopping oral liquor and preparation method thereof.

Background technology

Cough is the protectiveness respiratory reflex action that human body removes secretions in respiratory tract or foreign body, is the natural reaction of human body initiative defence.But cough is also a kind of nonspecific symptom of numerous disease, often due to the respiratory disease that Different types of etiopathogenises causes, causes the common disease of cough to have:

1) upper respiratory tract infection:

Namely catch a cold, be because virus enters into human body through nasal cavity and throat, cause the inflammation of upper respiratory tract mucosa.When children's catches cold, generally all can there is the symptom of coughing.

2) bronchitis:

Be because upper respiratory tract infection spreads mostly, morbidity is comparatively anxious, and the initial stage mostly is dry cough, and engender the discomforts such as cough, expectoration, occur anoxia time serious because of dyspnea, lip becomes livid purple color thereupon.Chronic bronchitis is the chronic nonspecific inflammation of trachea-bronchial epithelial cell mucosa caused by Different types of etiopathogenises and surrounding tissue thereof.Suffer from cold, smoking and flu often make primary disease bring out or increase the weight of.Main manifestations is chronic cough, expectoration, repeated infection clinically, or with panting.

3) pneumonia:

Children's within 2 years old is bronchopneumonia mostly, how to be caused by upper respiratory tract infection or bronchitis.Generally have dry cough, also there will be the phenomenons such as tachypnea, lip cyanosis, flaring of alaenasi.

4) acute laryngitis:

When virus or antibacterial are by throat, throat also can be caused to infect.Acute laryngitis is except dry cough and throat's pain, and most typical symptom is hoarseness, even can not send out sound.Sending the cough of picture dog sample when sucking air, time serious, laryngeal stridor occurring.

Senile asthma:

Cough, expectoration, rapid breathing, prolonged expiration, ictally to pant, uncomfortable in chest and chest tightness, especially nocturnal paroxysmal dyspnea.

Summary of the invention

The object of this invention is to provide one and there is cough stopping oral liquor and preparation method thereof, can be used for reducing heat and dispersing lung-QI, relieving asthma, sore-throat relieving, the disease such as cough, tracheitis, emphysema, asthma because sense air slaking heat causes can be used for.

In order to solve the problem existing for background technology, formula composition of the present invention and mass percent are: Radix Glycyrrhizae 10 ~ 20%, Radix Platycodonis 10 ~ 20%, Cornu Saigae Tataricae 10 ~ 20%, Radix Bupleuri 20 ~ 30%, Folium Eriobotryae 20 ~ 30%.

Its preparation method is:

1, mixed with water by above-mentioned medical material, part by weight is 1: 1 ~ 1: 50, boils at 50 ~ 100 DEG C of temperature, until aqueous solution is 1 ~ 100% of original medical material weight.

2, mix brewageing mature vinegar with the grain of 1 ~ 100% ratio after the juice of Fructus Hippophae adding 1 ~ 100% ratio in solution made in preparation process 1.

3, preserve at the temperature solution of preparation in preparation process 2 set within the scope of 0 ~ 20 DEG C.

The present invention is used for reducing heat and dispersing lung-QI, relievings asthma, sore-throat relieving, can be used for the disease such as cough, tracheitis, emphysema, asthma because sense air slaking heat causes.

Detailed description of the invention

The formula composition of this detailed description of the invention and mass percent are: Radix Glycyrrhizae 10 ~ 20%, Radix Platycodonis 10 ~ 20%, Cornu Saigae Tataricae 10 ~ 20%, Radix Bupleuri 20 ~ 30%, Folium Eriobotryae 20 ~ 30%.

Its preparation method is:

The rhizome of Radix Glycyrrhizae, its nature and flavor are sweet flat, GUIXIN, lung, spleen, stomach warp, and traditional medicine thinks that it has invigorating the spleen and replenishing QI, nourishing the lung to arrest cough, cures mainly weakness of the spleen and stomach, deficiency of QI in middle-JIAO, cough and asthma, swollen ulcer drug, food and drug intoxication, extremity and gastral cavity abdomen contraction be anxious has a pain and waits disease, therefore has saying of " ten medicines nine being careless ".

Juice of Fructus Hippophae contains high vitamin, and based on glucose, fructose in Fructus Hippophae, potassium, calcium, sodium, magnesium are available in all varieties.190 kinds more than are reached containing various trace element and bioactive substance.The effect that Fructus Hippophae has relieving cough and asthma in traditional medical theory, sharp lung reduces phlegm, all has fine effect to respiratory tract system diseases such as chronic pharyngitis, bronchitis, asthma, cough ant phlegms.Its effect is main with study on flavonoids in sea buckthorn antiinflammatory and promote that capillary blood Circulation is relevant.

Platycodin contained by Radix Platycodonis is to the direct stimulation of oral cavity, throat, gastric mucosa, and reflexive ground increases bronchial mucosa hypersecretion thus sputum is diluted, and is easy to discharge; Have antitussive effect, have and strengthen antiinflammatory and immunization, its antiinflammatory intensity is similar to aspirin simultaneously; Water extract can strengthen the phagocytic function of macrophage, strengthens the sterilizing power of neutrophilic leukocyte, improves lysozyme activity; Preventive effect is had to stress ulcer.

Cornu Saigae Tataricae subtracts cold, enters liver, the heart, lung meridian.Main removing fire from the liver, clear away heart-fire lung, and it can be used for the slight illness such as the treatment vertigo, liver-wind stirring up internally and infantile convulsion tic.Heat clearing away is relieving convulsion.Cornu Saigae Tataricae can heat-clearing and toxic substances removing, and spasmolytic is calmed the nerves.Loose blood removing toxic substances.Clearing away heat,cooling blood and removing toxin, multiplex carbuncle sore tumefacting virus heat in blood poison Sheng person.

Radix Bupleuri hardship is flat, and Gui Jing, enters liver, gallbladder meridian.Have antipyretic, bring down a fever, calm, analgesia, removes distending pain uncomfortable in chest, dissipating depression of QI regulating menoxenia; Inhibitory action is had to tubercule bacillus; Infected by influenza has strong inhibitory action, for cold, fever, alternate attack of chill and fever, malaria, and stagnation of QI due to depression of the liver, sternal rib pain.

Folium Eriobotryae is used for clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI, cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastropyretic vomiting, hiccup.Antitussive, eliminate the phlegm, antiasthmatic effect, the hydrocyanic acid that amygdalin contained by this product is hydrolyzed generation in vivo has antitussive action.Water decoction or ethyl acetate extract eliminate the phlegm and antiasthmatic effect, and the volatile oil contained by its leaf has slight phlegm-dispelling functions.

The above is only the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications also should be considered as protection scope of the present invention.

Claims

1. one kind has cough stopping oral liquor and preparation method thereof, it is characterized in that this formula composition and mass percent are: Radix Glycyrrhizae 10 ~ 20%, Radix Platycodonis 10 ~ 20%, Cornu Saigae Tataricae 10 ~ 20%, Radix Bupleuri 20 ~ 30%, Folium Eriobotryae 20 ~ 30%;

Its preparation method is:

1), by above-mentioned medical material mix with water, part by weight is 1: 1 ~ 1: 50, boils at 50 ~ 100 DEG C of temperature, until aqueous solution is 1 ~ 100% of original medical material weight;

2), mix brewageing mature vinegar with the grain of 1 ~ 100% ratio after the juice of Fructus Hippophae adding 1 ~ 100% ratio in solution made in preparation process 1;

3) preserve at the temperature, the solution of preparation in preparation process 2 set within the scope of 0 ~ 20 DEG C.