CN104562213A - 扩增子文库及其构建方法 - Google Patents
扩增子文库及其构建方法 Download PDFInfo
- Publication number
- CN104562213A CN104562213A CN201410835879.1A CN201410835879A CN104562213A CN 104562213 A CN104562213 A CN 104562213A CN 201410835879 A CN201410835879 A CN 201410835879A CN 104562213 A CN104562213 A CN 104562213A
- Authority
- CN
- China
- Prior art keywords
- pcr
- construction process
- sample
- amplified production
- joint
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410835879.1A CN104562213A (zh) | 2014-12-26 | 2014-12-26 | 扩增子文库及其构建方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410835879.1A CN104562213A (zh) | 2014-12-26 | 2014-12-26 | 扩增子文库及其构建方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN104562213A true CN104562213A (zh) | 2015-04-29 |
Family
ID=53079260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410835879.1A Pending CN104562213A (zh) | 2014-12-26 | 2014-12-26 | 扩增子文库及其构建方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104562213A (fi) |
Cited By (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105779437A (zh) * | 2016-03-11 | 2016-07-20 | 台州黄岩圣庭医学检验所 | 一种基于Ion PGMTM测序平台的扩增子DNA文库的构建方法、试剂及其应用 |
CN106282177A (zh) * | 2016-08-23 | 2017-01-04 | 厦门基源医疗科技有限公司 | 一种16S rDNA高通量测序文库的构建方法 |
CN106811460A (zh) * | 2015-11-30 | 2017-06-09 | 安诺优达基因科技(北京)有限公司 | 用于低频突变检测的二代测序文库的构建方法及试剂盒 |
CN106835291A (zh) * | 2016-12-14 | 2017-06-13 | 广州燃石医学检验所有限公司 | Dna 文库的制备方法以及试剂盒 |
CN107058573A (zh) * | 2016-06-13 | 2017-08-18 | 艾吉泰康生物科技(北京)有限公司 | 一种利用Cas9/gRNA系统构建扩增子文库的方法 |
WO2017219511A1 (zh) * | 2016-06-22 | 2017-12-28 | 杭州杰毅麦特医疗器械有限公司 | 一种快速均一化或等比例dna样本的方法 |
CN108929901A (zh) * | 2018-07-27 | 2018-12-04 | 博奥生物集团有限公司 | 一种用于痕量dna的多重扩增建库方法及其专用试剂盒 |
CN109996876A (zh) * | 2016-08-22 | 2019-07-09 | 特韦斯特生物科学公司 | 从头合成的核酸文库 |
US10844373B2 (en) | 2015-09-18 | 2020-11-24 | Twist Bioscience Corporation | Oligonucleic acid variant libraries and synthesis thereof |
CN112176032A (zh) * | 2020-10-16 | 2021-01-05 | 广州市达瑞生物技术股份有限公司 | 一个呼吸道病原体的纳米孔测序建库的引物组合及其应用 |
US10894242B2 (en) | 2017-10-20 | 2021-01-19 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
US10894959B2 (en) | 2017-03-15 | 2021-01-19 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
US10907274B2 (en) | 2016-12-16 | 2021-02-02 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
US10936953B2 (en) * | 2018-01-04 | 2021-03-02 | Twist Bioscience Corporation | DNA-based digital information storage with sidewall electrodes |
US10987648B2 (en) | 2015-12-01 | 2021-04-27 | Twist Bioscience Corporation | Functionalized surfaces and preparation thereof |
CN113046418A (zh) * | 2021-04-02 | 2021-06-29 | 武汉博越致和生物科技有限公司 | 一种用于妊娠期糖尿病肠道菌群检测16S rDNA扩增子建库方法 |
US11185837B2 (en) | 2013-08-05 | 2021-11-30 | Twist Bioscience Corporation | De novo synthesized gene libraries |
US11263354B2 (en) | 2016-09-21 | 2022-03-01 | Twist Bioscience Corporation | Nucleic acid based data storage |
US11332738B2 (en) | 2019-06-21 | 2022-05-17 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
US11332740B2 (en) | 2017-06-12 | 2022-05-17 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
US11377676B2 (en) | 2017-06-12 | 2022-07-05 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
US11407837B2 (en) | 2017-09-11 | 2022-08-09 | Twist Bioscience Corporation | GPCR binding proteins and synthesis thereof |
CN115232863A (zh) * | 2022-09-03 | 2022-10-25 | 杭州联川生物技术股份有限公司 | 一种基于磁珠的均一化建库试剂盒和方法 |
US11492665B2 (en) | 2018-05-18 | 2022-11-08 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
US11492727B2 (en) | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for GLP1 receptor |
US11492728B2 (en) | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
US11512347B2 (en) | 2015-09-22 | 2022-11-29 | Twist Bioscience Corporation | Flexible substrates for nucleic acid synthesis |
US11550939B2 (en) | 2017-02-22 | 2023-01-10 | Twist Bioscience Corporation | Nucleic acid based data storage using enzymatic bioencryption |
US11691118B2 (en) | 2015-04-21 | 2023-07-04 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
US11697668B2 (en) | 2015-02-04 | 2023-07-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
US12091777B2 (en) | 2019-09-23 | 2024-09-17 | Twist Bioscience Corporation | Variant nucleic acid libraries for CRTH2 |
CN118726543A (zh) * | 2024-09-03 | 2024-10-01 | 北京百迈客生物科技有限公司 | 微生物扩增子文库自动化构建方法、装置及系统 |
US12173282B2 (en) | 2019-09-23 | 2024-12-24 | Twist Bioscience, Inc. | Antibodies that bind CD3 epsilon |
US12357959B2 (en) | 2018-12-26 | 2025-07-15 | Twist Bioscience Corporation | Highly accurate de novo polynucleotide synthesis |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101967476A (zh) * | 2010-09-21 | 2011-02-09 | 深圳华大基因科技有限公司 | 一种基于接头连接的DNA PCR-Free标签文库构建方法 |
CN103045726A (zh) * | 2012-11-20 | 2013-04-17 | 南方科技大学 | 对多个混合dna或rna序列进行基因测序的方法及装置 |
US20130184165A1 (en) * | 2012-01-13 | 2013-07-18 | Data2Bio | Genotyping by next-generation sequencing |
CN104153004A (zh) * | 2014-08-11 | 2014-11-19 | 上海美吉生物医药科技有限公司 | 一种用于扩增子测序的建库方法 |
-
2014
- 2014-12-26 CN CN201410835879.1A patent/CN104562213A/zh active Pending
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101967476A (zh) * | 2010-09-21 | 2011-02-09 | 深圳华大基因科技有限公司 | 一种基于接头连接的DNA PCR-Free标签文库构建方法 |
US20130184165A1 (en) * | 2012-01-13 | 2013-07-18 | Data2Bio | Genotyping by next-generation sequencing |
CN103045726A (zh) * | 2012-11-20 | 2013-04-17 | 南方科技大学 | 对多个混合dna或rna序列进行基因测序的方法及装置 |
CN104153004A (zh) * | 2014-08-11 | 2014-11-19 | 上海美吉生物医药科技有限公司 | 一种用于扩增子测序的建库方法 |
Cited By (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11452980B2 (en) | 2013-08-05 | 2022-09-27 | Twist Bioscience Corporation | De novo synthesized gene libraries |
US11185837B2 (en) | 2013-08-05 | 2021-11-30 | Twist Bioscience Corporation | De novo synthesized gene libraries |
US11559778B2 (en) | 2013-08-05 | 2023-01-24 | Twist Bioscience Corporation | De novo synthesized gene libraries |
US11697668B2 (en) | 2015-02-04 | 2023-07-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
US11691118B2 (en) | 2015-04-21 | 2023-07-04 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
US10844373B2 (en) | 2015-09-18 | 2020-11-24 | Twist Bioscience Corporation | Oligonucleic acid variant libraries and synthesis thereof |
US11807956B2 (en) | 2015-09-18 | 2023-11-07 | Twist Bioscience Corporation | Oligonucleic acid variant libraries and synthesis thereof |
US11512347B2 (en) | 2015-09-22 | 2022-11-29 | Twist Bioscience Corporation | Flexible substrates for nucleic acid synthesis |
US11248228B2 (en) | 2015-11-30 | 2022-02-15 | Nanjing Annoroad Gene Technology Co. Ltd | Method for constructing next-generation sequencing library for detection of lowfrequency mutation and kit thereof |
CN106811460A (zh) * | 2015-11-30 | 2017-06-09 | 安诺优达基因科技(北京)有限公司 | 用于低频突变检测的二代测序文库的构建方法及试剂盒 |
US10987648B2 (en) | 2015-12-01 | 2021-04-27 | Twist Bioscience Corporation | Functionalized surfaces and preparation thereof |
CN105779437A (zh) * | 2016-03-11 | 2016-07-20 | 台州黄岩圣庭医学检验所 | 一种基于Ion PGMTM测序平台的扩增子DNA文库的构建方法、试剂及其应用 |
CN107058573A (zh) * | 2016-06-13 | 2017-08-18 | 艾吉泰康生物科技(北京)有限公司 | 一种利用Cas9/gRNA系统构建扩增子文库的方法 |
WO2017219511A1 (zh) * | 2016-06-22 | 2017-12-28 | 杭州杰毅麦特医疗器械有限公司 | 一种快速均一化或等比例dna样本的方法 |
CN109996876A (zh) * | 2016-08-22 | 2019-07-09 | 特韦斯特生物科学公司 | 从头合成的核酸文库 |
US10975372B2 (en) | 2016-08-22 | 2021-04-13 | Twist Bioscience Corporation | De novo synthesized nucleic acid libraries |
CN106282177A (zh) * | 2016-08-23 | 2017-01-04 | 厦门基源医疗科技有限公司 | 一种16S rDNA高通量测序文库的构建方法 |
US11562103B2 (en) | 2016-09-21 | 2023-01-24 | Twist Bioscience Corporation | Nucleic acid based data storage |
US11263354B2 (en) | 2016-09-21 | 2022-03-01 | Twist Bioscience Corporation | Nucleic acid based data storage |
US12056264B2 (en) | 2016-09-21 | 2024-08-06 | Twist Bioscience Corporation | Nucleic acid based data storage |
CN106835291A (zh) * | 2016-12-14 | 2017-06-13 | 广州燃石医学检验所有限公司 | Dna 文库的制备方法以及试剂盒 |
US10907274B2 (en) | 2016-12-16 | 2021-02-02 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
US11550939B2 (en) | 2017-02-22 | 2023-01-10 | Twist Bioscience Corporation | Nucleic acid based data storage using enzymatic bioencryption |
US10894959B2 (en) | 2017-03-15 | 2021-01-19 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
US11332740B2 (en) | 2017-06-12 | 2022-05-17 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
US11377676B2 (en) | 2017-06-12 | 2022-07-05 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
US12270028B2 (en) | 2017-06-12 | 2025-04-08 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
US11407837B2 (en) | 2017-09-11 | 2022-08-09 | Twist Bioscience Corporation | GPCR binding proteins and synthesis thereof |
US11745159B2 (en) | 2017-10-20 | 2023-09-05 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
US10894242B2 (en) | 2017-10-20 | 2021-01-19 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
US12086722B2 (en) | 2018-01-04 | 2024-09-10 | Twist Bioscience Corporation | DNA-based digital information storage with sidewall electrodes |
US10936953B2 (en) * | 2018-01-04 | 2021-03-02 | Twist Bioscience Corporation | DNA-based digital information storage with sidewall electrodes |
US11492665B2 (en) | 2018-05-18 | 2022-11-08 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
US11732294B2 (en) | 2018-05-18 | 2023-08-22 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
CN108929901B (zh) * | 2018-07-27 | 2022-02-01 | 博奥生物集团有限公司 | 一种用于痕量dna的多重扩增建库方法及其专用试剂盒 |
CN108929901A (zh) * | 2018-07-27 | 2018-12-04 | 博奥生物集团有限公司 | 一种用于痕量dna的多重扩增建库方法及其专用试剂盒 |
US12357959B2 (en) | 2018-12-26 | 2025-07-15 | Twist Bioscience Corporation | Highly accurate de novo polynucleotide synthesis |
US11492728B2 (en) | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
US11492727B2 (en) | 2019-02-26 | 2022-11-08 | Twist Bioscience Corporation | Variant nucleic acid libraries for GLP1 receptor |
US12331427B2 (en) | 2019-02-26 | 2025-06-17 | Twist Bioscience Corporation | Antibodies that bind GLP1R |
US11332738B2 (en) | 2019-06-21 | 2022-05-17 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
US12091777B2 (en) | 2019-09-23 | 2024-09-17 | Twist Bioscience Corporation | Variant nucleic acid libraries for CRTH2 |
US12173282B2 (en) | 2019-09-23 | 2024-12-24 | Twist Bioscience, Inc. | Antibodies that bind CD3 epsilon |
CN112176032A (zh) * | 2020-10-16 | 2021-01-05 | 广州市达瑞生物技术股份有限公司 | 一个呼吸道病原体的纳米孔测序建库的引物组合及其应用 |
CN112176032B (zh) * | 2020-10-16 | 2021-10-26 | 广州市达瑞生物技术股份有限公司 | 一个呼吸道病原体的纳米孔测序建库的引物组合及其应用 |
CN113046418A (zh) * | 2021-04-02 | 2021-06-29 | 武汉博越致和生物科技有限公司 | 一种用于妊娠期糖尿病肠道菌群检测16S rDNA扩增子建库方法 |
CN115232863A (zh) * | 2022-09-03 | 2022-10-25 | 杭州联川生物技术股份有限公司 | 一种基于磁珠的均一化建库试剂盒和方法 |
CN118726543A (zh) * | 2024-09-03 | 2024-10-01 | 北京百迈客生物科技有限公司 | 微生物扩增子文库自动化构建方法、装置及系统 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104562213A (zh) | 扩增子文库及其构建方法 | |
Pereira et al. | Mixed Eucalyptus plantations induce changes in microbial communities and increase biological functions in the soil and litter layers | |
CN104293783A (zh) | 适用于扩增子测序文库构建的引物、构建方法、扩增子文库及包含其的试剂盒 | |
CN104561294B (zh) | 基因分型测序文库的构建方法和测序方法 | |
CN104263726A (zh) | 适用于扩增子测序文库构建的引物及扩增子测序文库的构建方法 | |
CN102477460A (zh) | 对宏基因组16s高可变区v6进行测序聚类分析的方法 | |
CN102517392A (zh) | 基于宏基因组16s高可变区v3的分类方法和装置 | |
CN107292123A (zh) | 一种基于高通量测序的微生物群落组成的方法和装置 | |
CN101748213A (zh) | 一种环境微生物检测方法和系统 | |
CN105986015A (zh) | 一种基于高通量测序的多样本的一个或多个靶序列的检测方法和试剂盒 | |
CN107829146A (zh) | 一种用于构建16SrRNA基因扩增子测序文库的引物组及构建方法 | |
CN106367496B (zh) | 一套猕猴桃物种关联特异单核苷酸分子标记及其检测引物组和应用 | |
CN106636393A (zh) | 与南瓜皮色基因连锁的snp分子标记及其应用 | |
CN106995836A (zh) | 二代测序样品前处理的引物和方法以及试剂盒 | |
CN105087560B (zh) | 一种基于高通量测序构建猪bcr重链文库的多重pcr引物和方法 | |
CN106192022A (zh) | 16SrRNA多重测序文库的构建方法 | |
CN113151567B (zh) | 用于鉴别花脸香蘑n006#菌株的ssr分子标记及方法 | |
CN113142034B (zh) | 同步鉴定水生生态系统中浮游藻类和底栖藻类的方法 | |
CN106191045B (zh) | 用于多重核酸测序的Index和引物 | |
CN104404154B (zh) | 浮游动物rrnL基因扩增引物及其筛选方法和应用及应用方法 | |
CN104293887B (zh) | 杨属派间不同种亲缘关系的鉴定方法及鉴定试剂盒 | |
CN107828858A (zh) | 一种基于转录组测序开发鬼针草植物ssr引物的方法 | |
Kust et al. | Model cyanobacterial consortia reveal a consistent core microbiome independent of inoculation source or cyanobacterial host species | |
CN104212897B (zh) | 一种大批量开发苎麻基因组ssr标记的方法及其开发的引物 | |
CN104212898B (zh) | 一种大批量开发苎麻基因组snp标记的方法及其开发的引物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150429 |
|
RJ01 | Rejection of invention patent application after publication |