CN104547851A - Medicament for treating high blood pressure - Google Patents
Medicament for treating high blood pressure Download PDFInfo
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- CN104547851A CN104547851A CN201410318315.0A CN201410318315A CN104547851A CN 104547851 A CN104547851 A CN 104547851A CN 201410318315 A CN201410318315 A CN 201410318315A CN 104547851 A CN104547851 A CN 104547851A
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- 239000003814 drug Substances 0.000 title claims abstract description 37
- 206010020772 Hypertension Diseases 0.000 title claims abstract description 21
- 230000001631 hypertensive effect Effects 0.000 claims description 14
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 12
- 239000002775 capsule Substances 0.000 claims description 9
- 239000002994 raw material Substances 0.000 claims description 7
- 241000269417 Bufo Species 0.000 claims description 6
- 241000283956 Manis Species 0.000 claims description 6
- 229910000960 colored gold Inorganic materials 0.000 claims description 6
- 239000009806 pulsatillae Substances 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 6
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 6
- 239000002552 dosage form Substances 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 2
- 239000007788 liquid Substances 0.000 claims description 2
- 239000006187 pill Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 10
- 208000024891 symptom Diseases 0.000 abstract description 5
- 230000002045 lasting effect Effects 0.000 abstract description 3
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- 235000008598 Paeonia lactiflora Nutrition 0.000 abstract 2
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- WTPPRJKFRFIQKT-UHFFFAOYSA-N 1,6-dimethyl-8,9-dihydronaphtho[1,2-g][1]benzofuran-10,11-dione;1-methyl-6-methylidene-8,9-dihydro-7h-naphtho[1,2-g][1]benzofuran-10,11-dione Chemical compound O=C1C(=O)C2=C3CCCC(=C)C3=CC=C2C2=C1C(C)=CO2.O=C1C(=O)C2=C3CCC=C(C)C3=CC=C2C2=C1C(C)=CO2 WTPPRJKFRFIQKT-UHFFFAOYSA-N 0.000 abstract 1
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- 241000196324 Embryophyta Species 0.000 abstract 1
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- 241000305492 Gastrodia Species 0.000 abstract 1
- 235000013717 Houttuynia Nutrition 0.000 abstract 1
- 240000000691 Houttuynia cordata Species 0.000 abstract 1
- 241000234435 Lilium Species 0.000 abstract 1
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- 244000081822 Uncaria gambir Species 0.000 abstract 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 abstract 1
- 239000010931 gold Substances 0.000 abstract 1
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- 239000007787 solid Substances 0.000 abstract 1
- 239000012567 medical material Substances 0.000 description 5
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- 230000001954 sterilising effect Effects 0.000 description 5
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- 230000036772 blood pressure Effects 0.000 description 4
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- DNXIKVLOVZVMQF-UHFFFAOYSA-N (3beta,16beta,17alpha,18beta,20alpha)-17-hydroxy-11-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(O)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 DNXIKVLOVZVMQF-UHFFFAOYSA-N 0.000 description 1
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- QEVHRUUCFGRFIF-SFWBKIHZSA-N Reserpine Natural products O=C(OC)[C@@H]1[C@H](OC)[C@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)C[C@H]2[C@@H]1C[C@H]1N(C2)CCc2c3c([nH]c12)cc(OC)cc3 QEVHRUUCFGRFIF-SFWBKIHZSA-N 0.000 description 1
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- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 238000003748 differential diagnosis Methods 0.000 description 1
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- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 description 1
- 229960003147 reserpine Drugs 0.000 description 1
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 description 1
- 230000035488 systolic blood pressure Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Classifications
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- A61K36/8988—Gastrodia
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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- A61K35/56—Materials from animals other than mammals
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Abstract
The invention discloses a medicament for treating high blood pressure. The medicament is mainly prepared from the following medicaments according to appropriate proportions: tall gastrodia tuber, gambir plant, baikal skullcap root, white peony root, danshen root, eucommia bark, puncturevine caltrop fruit, pangolin scales, cassia seeds, white peony root, humifuse euphorbia herb, villous amomum fruit, solid gold, dried toads, Chinese pulsatilla root, heartleaf houttuynia herb, philippine violet herb and lily. The medicament disclosed by the invention is prepared from various traditional Chinese medicinal materials, is significant, stable and lasting in curative effect of treating high blood pressure symptoms, has a total treatment efficiency of reaching up to 99.2%, can avoid relapse after cure, and does not have toxic or side effect, thereby relieving patients from later worries.
Description
Technical field
The present invention relates to one and treat hypertensive medicine, the medicine of specifically a kind of pure raw material of Chinese medicine preparation, belongs to Chinese medicine formula technical field.
Background technology
Hypertension is the modal cardiovascular disease in the world, and be also one of maximum epidemic diseases, often cause the complication of the internal organs such as the heart, brain, kidney, the health of the mankind in serious harm.Current China Hypertensive Population is more than 2.6 hundred million, and the sickness rate of hypertension in adult reaches 20%, but along with the raising of people's living standard, dietary structure collocation is unreasonable, and this ratio also has the trend risen.Clinical in hypertensive treatment, people widely use various Western medicine depressor, as antihypertensive drugs such as compound recipe reserpine, FUFANG JIANGYA PIAN, need long-term taking, have larger side effect to human body, and they can only take stopgap measures, can not effect a permanent cure.Chinese and Western medicine is compared, and side effect is obviously little, and curative effect is lasting.Also there are some in the market and treat hypertensive Chinese medicine, but its therapeutic effect is unsatisfactory.
Summary of the invention
Technical problem to be solved by this invention is to provide one and treats hypertensive medicine, and it can be used for treatment essential hypertension and secondary hypertension, and curative effect is high, instant effect, and safe without toxic side effect.
The technical solution used in the present invention is:
One treats hypertensive medicine, it is characterized in that, the raw material of following weight portion is adopted to make: Rhizoma Gastrodiae 8 ~ 12, Ramulus Uncariae Cum Uncis 10 ~ 14, Radix Scutellariae 8 ~ 12, the Radix Paeoniae Alba 8 ~ 12, Radix Salviae Miltiorrhizae 5-10, the Cortex Eucommiae 8 ~ 12, Fructus Tribuli 10-15, Squama Manis 5-10, Semen Cassiae 10-20, Radix Paeoniae Alba 10-15, Herba Euphorbiae Humifusae 5-10, Fructus Amomi 5-10, deep coloured gold 5-10, Bufo siccus 5-10, Radix Pulsatillae 5-10, Herba Houttuyniae 10-15, Herba Violae 8 ~ 12, Bulbus Lilii 5-10.
Said medicine can be made any one dosage form on pharmaceutics, as tablet, capsule, pill, granule, oral liquid or decoction.Preparation technique means well known in the art can be adopted to complete the preparation of medicament of the present invention.
Preferred dosage form of the present invention is capsule.Above medical material is joined by measuring, and pulverized by described medicine as powder crosses 100 mesh sieves afterwards, mixing sterilization incapsulates, and each capsule gets product by 0.4 gram of dress.
The invention has the beneficial effects as follows: formulated owing to have employed several kinds of Chinese medicinal materials, its goods include multi-medicament composition, evident in efficacy, stable lasting, can cure hypertension rapidly, and rear without recurrence, have no side effect, relieve the trouble and worry of patient.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further details.
Embodiment 1
Hypertensive medicine is treated in the present embodiment, be made up of the raw material of following weight portion: Rhizoma Gastrodiae 10 g, Ramulus Uncariae Cum Uncis 12 g, Radix Scutellariae 10 g, the Radix Paeoniae Alba 10 g, Radix Salviae Miltiorrhizae 7 g, the Cortex Eucommiae 10 g, Fructus Tribuli 12 g, Squama Manis 8 g, Semen Cassiae 15 g, the Radix Paeoniae Alba 12 g, Herba Euphorbiae Humifusae 7 g, Fructus Amomi 7 g, deep coloured gold 8 g, Bufo siccus 8 g, the Radix Pulsatillae 7 g, Herba Houttuyniae 12 g, Herba Violae 10 g, Bulbus Lilii 6 g.Above medical material is joined by measuring, and pulverized by described medicine as powder crosses 100 mesh sieves afterwards, mixing sterilization incapsulates, and each capsule gets product by 0.4 gram of dress.
Usage and consumption: every day 3 times, one time 2, taking 5 days is a course for the treatment of.
Embodiment 2
Hypertensive medicine is treated in the present embodiment, be made up of the raw material of following weight portion: Rhizoma Gastrodiae 8 g, Ramulus Uncariae Cum Uncis 10 g, Radix Scutellariae 8 g, the Radix Paeoniae Alba 8 g, Radix Salviae Miltiorrhizae 5 g, the Cortex Eucommiae 8 g, Fructus Tribuli 10 g, Squama Manis 5 g, Semen Cassiae 10 g, the Radix Paeoniae Alba 10 g, Herba Euphorbiae Humifusae 5 g, Fructus Amomi 5 g, deep coloured gold 5 g, Bufo siccus 5 g, the Radix Pulsatillae 5 g, Herba Houttuyniae 10 g, Herba Violae 8 g, Bulbus Lilii 5 g.Above medical material is joined by measuring, and pulverized by described medicine as powder crosses 100 mesh sieves afterwards, mixing sterilization incapsulates, and each capsule gets product by 0.4 gram of dress.
Usage and consumption: every day 3 times, one time 2, taking 5 days is a course for the treatment of.
Embodiment 3
Hypertensive medicine is treated in the present embodiment, be made up of the raw material of following weight portion: Rhizoma Gastrodiae 9 g, Ramulus Uncariae Cum Uncis 11 g, Radix Scutellariae 11 g, the Radix Paeoniae Alba 11 g, Radix Salviae Miltiorrhizae 8 g, the Cortex Eucommiae 9 g, Fructus Tribuli 13 g, Squama Manis 6 g, Semen Cassiae 17 g, Radix Paeoniae Alba 13g, Herba Euphorbiae Humifusae 6 g, Fructus Amomi 7 g, deep coloured gold 8 g, Bufo siccus 6 g, the Radix Pulsatillae 8 g, Herba Houttuyniae 11 g, Herba Violae 9 g, Bulbus Lilii 7 g.Above medical material is joined by measuring, and pulverized by described medicine as powder crosses 100 mesh sieves afterwards, mixing sterilization incapsulates, and each capsule gets product by 0.4 gram of dress.
Usage and consumption: every day 3 times, one time 2, taking 5 days is a course for the treatment of.
Embodiment 4
Hypertensive medicine is treated in the present embodiment, be made up of the raw material of following weight portion: Rhizoma Gastrodiae 12 g, Ramulus Uncariae Cum Uncis 14 g, Radix Scutellariae 12 g, the Radix Paeoniae Alba 12 g, Radix Salviae Miltiorrhizae 10 g, the Cortex Eucommiae 12 g, Fructus Tribuli 15 g, Squama Manis 10 g, Semen Cassiae 20 g, the Radix Paeoniae Alba 15 g, Herba Euphorbiae Humifusae 10 g, Fructus Amomi 10 g, deep coloured gold 10 g, Bufo siccus 10 g, the Radix Pulsatillae 10 g, Herba Houttuyniae 15 g, Herba Violae 12 g, Bulbus Lilii 10 g.Above medical material is joined by measuring, and pulverized by described medicine as powder crosses 100 mesh sieves afterwards, mixing sterilization incapsulates, and each capsule gets product by 0.4 gram of dress.
Usage and consumption: every day 3 times, one time 2, taking 5 days is a course for the treatment of.
Test case
1, clinical data
Stochastic choice hyperpietic 130 example, observes the clinical effectiveness after using medicine of the present invention.Wherein man 55 example, female 75 example, 53 years old mean age.
2, diagnostic criteria
Western medicine diagnose standard: systolic pressure is equal to or higher than 140mmHg, diastolic pressure is equal to or higher than 90mmHg, both have one to examine, and can make a definite diagnosis.Differential diagnosis in tcm standard cardinal symptom: dizzy, headache, cardiopalmus, tinnitus, insomnia, agitation, waist soreness etc.
3, Therapeutic Method
Whole test case patient to take in the embodiment of the present invention 2 obtained medicine, 3 times on the one, one time 2.Within 5 days, be a course for the treatment of, after course for the treatment of medication, check blood pressure.
4, curative effect determinate standard
Cure: clinical symptoms all disappears, and blood pressure is down to normally, and does not recur in 1 year.Effective: clinical symptoms all disappears, after taking medicine, blood pressure declines to some extent but is not down to normal.Invalid: clinical symptoms does not change, before and after treatment, blood pressure does not obviously change.
5, the results are shown in Table 1 after case treatment.
Table 1 hypertension clinical treatment outcome
| Case load | Cure n(%) | Effective n(%) | Invalid n(%) | Total effective rate n(%) | |
| Test case | 130 | 121（93.1） | 8（6.1） | 1（0.8） | 129（99.2） |
Claims (3)
1. the hypertensive medicine for the treatment of, it is characterized in that, be made up of the raw material of following weight portion: Rhizoma Gastrodiae 8 ~ 12, Ramulus Uncariae Cum Uncis 10 ~ 14, Radix Scutellariae 8 ~ 12, the Radix Paeoniae Alba 8 ~ 12, Radix Salviae Miltiorrhizae 5-10, the Cortex Eucommiae 8 ~ 12, Fructus Tribuli 10-15, Squama Manis 5-10, Semen Cassiae 10-20, Radix Paeoniae Alba 10-15, Herba Euphorbiae Humifusae 5-10, Fructus Amomi 5-10, deep coloured gold 5-10, Bufo siccus 5-10, Radix Pulsatillae 5-10, Herba Houttuyniae 10-15, Herba Violae 8 ~ 12, Bulbus Lilii 5-10.
2. the hypertensive medicine for the treatment of according to claim 1, is characterized in that, described medicament is any one dosage form described in pharmaceutics, as tablet, capsule, granule, pill, oral liquid or decoction etc.
3. the hypertensive medicine for the treatment of according to claim 1, is characterized in that, described medicine is capsule.
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| CN201410318315.0A CN104547851B (en) | 2014-07-07 | 2014-07-07 | One treats hypertensive medicine |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410318315.0A CN104547851B (en) | 2014-07-07 | 2014-07-07 | One treats hypertensive medicine |
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| CN104547851B CN104547851B (en) | 2015-09-30 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111643510A (en) * | 2019-10-31 | 2020-09-11 | 广西林洋药业有限公司 | Application of anemonin B4 in preparation of medicine for lowering blood pressure |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1373190A (en) * | 2001-03-07 | 2002-10-09 | 陈列 | Process for preapring health-care lily bulb-dried ginger liquor |
| CN101890133A (en) * | 2010-07-09 | 2010-11-24 | 向文忠 | Medicine for lowering high blood pressure |
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2014
- 2014-07-07 CN CN201410318315.0A patent/CN104547851B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1373190A (en) * | 2001-03-07 | 2002-10-09 | 陈列 | Process for preapring health-care lily bulb-dried ginger liquor |
| CN101890133A (en) * | 2010-07-09 | 2010-11-24 | 向文忠 | Medicine for lowering high blood pressure |
Non-Patent Citations (1)
| Title |
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| 孟凡珍等: "中药复方治疗高血压用药规律分析", 《中成药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111643510A (en) * | 2019-10-31 | 2020-09-11 | 广西林洋药业有限公司 | Application of anemonin B4 in preparation of medicine for lowering blood pressure |
| CN111643510B (en) * | 2019-10-31 | 2023-03-14 | 广西林洋药业有限公司 | Application of white head Weng Zaogan B4 in preparation of antihypertensive drug |
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| Publication number | Publication date |
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| CN104547851B (en) | 2015-09-30 |
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