CN104547434B - One treats chronic prostatitis Chinese medicine composition - Google Patents

One treats chronic prostatitis Chinese medicine composition Download PDF

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CN104547434B
CN104547434B CN201510081584.4A CN201510081584A CN104547434B CN 104547434 B CN104547434 B CN 104547434B CN 201510081584 A CN201510081584 A CN 201510081584A CN 104547434 B CN104547434 B CN 104547434B
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medicine composition
chinese medicine
chronic prostatitis
fructus
crude drug
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CN104547434A (en
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王克霞
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Wang Kexia
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Abstract

The open one of the present invention treats chronic prostatitis Chinese medicine composition and preparation method thereof, belongs to tcm field.Be prepared from by the Chinese crude drug of following portions by weight: Radix Sophorae Tonkinensis 30-60, Semen Cuscutae 8-24, Fructus Schisandrae Chinensis 8-24, Rhizoma Dioscoreae 18-36, Carapax Trionycis 6-18, Fructus Gardeniae 30-60, Radix Astragali 6-18, Fructus Liquidambaris 6-18 and Radix Glycyrrhizae 6-18.The all medicines of the present invention with the use of, can complement each other, cooperative gain, plays the effect such as heat-clearing and toxic substances removing profit, diuretic dehumidifying, the kidney invigorating arresting seminal emission, hard masses softening and resolving, has therapeutic effect significantly to prostatitis, prostate hyperplasia.

Description

One treats chronic prostatitis Chinese medicine composition
Technical field
The open one of the present invention treats chronic prostatitis Chinese medicine composition, belongs to tcm field.
Technical background
Prostate is the distinctive sexual glands of male, has the property secreting gland of inside and outside dual secretory function.Prostate morbidity not only can cause local do not accommodate symptom, the more important thing is, also can cause General Symptoms and discomfort, even cause the malignant disease such as uremia, tumor.
Along with the modern quickening of people's rhythm of life and the mixed and disorderly of dietary structure, prostatosis is rejuvenation gradually, and the sickness rate of person in middle and old age's prostatosis also progressively increases.The scorching disease in prostatitis occurs with premature ejaculation sometimes simultaneously, and the cardinal symptom of prostatic hyperplasia has dysuria, and the lighter's total urination time of getting up at night increases, and has urine retention or also has a small amount of phenomenon of discharging after having urinated; Severe patient occurs that urine stream attenuates, even the phenomenon of can not arranging; Same often with symptoms such as soreness of waist lumbago, myasthenia of limbs, seminal emissions.The harm of prostatosis to human body is many-sided, on short terms, can cause the untoward reaction such as insomnia and dreamful sleep, weak dizziness, lumbus sacrum pain, inappetence, nausea and vomiting.On long terms, pathogenic bacterium along the up infection of Posterior urethral, can cause Posterior urethral inflammation, also can follow deferent duct and come downwards to scrotum, bring out epididymo orchitis.
At present, the method for chemicals and operation is treatment prostatitis is Therapeutic Method the most frequently used at present, and easily repeatedly, weak effect, wound is large for right existing method.
Summary of the invention
It is high that the technical problem to be solved in the present invention is to provide a kind of cure rate, do not recur more, instant effect, the Chinese medicine composition of the treatment chronic prostatitis of short treating period.
For solving the problems of the technologies described above, inventor combines tcm clinical practice for many years and to practise medicine experience, is repeatedly verified and adjusts, provide a kind of Chinese medicine composition for the treatment of chronic prostatitis, it is characterized in that, be prepared from by the Chinese crude drug of following portions by weight by clinical practice:
Preferably, the present invention treats the Chinese medicine composition of chronic prostatitis, it is characterized in that, is prepared from by the Chinese crude drug of following portions by weight:
In Chinese medicine composition of the present invention Chinese medicine composition used, each composition pharmacology is as follows:
Radix Sophorae Tonkinensis:
[nature and flavor] are bitter, cold; Poisonous.
[return through] attaches to the lung and stomach meridians.
[function cures mainly] heat-clearing and toxic substances removing, detumescence sore-throat relieving.Pent up for fire-toxin, laryngopharynx swelling and pain, gingivitis.
Semen Cuscutae: [nature and flavor] are sweet, temperature.
[return through] returns liver,kidney,spleen warp.
[function cures mainly] nourishing the liver and kidney, controlling nocturnal emission with astringent drugs reducing urination, antiabortive, improving eyesight, antidiarrheal.For impotence and seminal emission, dripping urination, enuresis frequent micturition, soreness of the waist and knees, blurred vision tinnitus, vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement, spleen is suffered from a deficiency of the kidney and is rushed down; Externally treating leucoderma.
Fructus Schisandrae Chinensis: [nature and flavor] are sour, sweet, temperature.
[return through] returns lung, the heart, kidney channel.
[function cures mainly] restrains astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Rhizoma Dioscoreae: [nature and flavor] are sweet, flat.
[return through] returns spleen, lung, kidney channel.
[function cures mainly] spleen reinforcing nourishing the stomach, promote the production of body fluid lung benefiting, the kidney invigorating arresting seminal emission.For insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, and deficiency-heat is quenched one's thirst.Rhizoma Dioscoreae (parched with bran) spleen reinforcing stomach invigorating.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, leukorrhagia.
Carapax Trionycis: [nature and flavor] are salty, are slightly cold.
[return through] returns liver, kidney channel.
[function cures mainly] nourishing YIN for suppressing the hyperactive YANG, hard masses softening and resolving, brings down a fever except steaming.For fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring-up of pathogenic wind in the interior resulting from deficiency, amenorrhea , WEIJIA, chronic malaria malaria with splenomegaly
Fructus Gardeniae: [nature and flavor] are bitter, cold.
[return through] GUIXIN, lung, tri-jiao channel.
[function cures mainly] fruit: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles; External treatment bruise pain.
The Radix Astragali: [nature and flavor] are sweet, temperature.
[return through] returns lung, spleen channel.
[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Fructus Liquidambaris: [nature and flavor] are bitter is flat.
[return through] returns liver, kidney channel.
[function cures mainly] dispelling, collateral-activating, diuretic stimulates the menstrual flow.For arthralgia, numbness contracture, edema distension, the few amenorrhea of breast.
Radix Glycyrrhizae: [nature and flavor] are sweet, flat.
[return through] GUIXIN, lung, spleen, stomach warp.
[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Present invention also offers a kind of preparation method for the treatment of chronic prostatitis Chinese medicine composition, it is characterized in that comprising following steps:
(1), in prescription ratio each taste Chinese crude drug is accurately taken, for subsequent use.
(2), by Radix Sophorae Tonkinensis, Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Gardeniae, Fructus Liquidambaris grind respectively, add the purified water of medical material 5-10 times weight, soak 0.5-2 hour, decoct 1-3 hour, filter; Filtering residue adds 3-5 times of water gaging, decocts 1-3 hour; Filter, merge twice filtrate; Concentrated filtrate, dry, pulverize into 80 object fine powders, for subsequent use.
(3), by Rhizoma Dioscoreae, Carapax Trionycis, the Radix Astragali, Radix Glycyrrhizae mixing, 80 object fine powders were ground into, for subsequent use.
(4), by step 3 and step 4 gained fine powder mix homogeneously, sterilizing is prepared into the solid dosage formss such as tablet, powder, pill, granule or capsule.
The all medicines of the present invention with the use of, can complement each other, cooperative gain, plays the effect such as heat-clearing and toxic substances removing profit, diuretic dehumidifying, the kidney invigorating arresting seminal emission, hard masses softening and resolving, has therapeutic effect significantly to prostatitis, prostate hyperplasia.
Compared with prior art, the present invention treats chronic prostatitis Chinese medicine composition, and to have cure rate high, do not recur, instant effect more, and short treating period, safety is high, dosage is low, the advantages such as no side effects.And its preparation method is simple, be easy to apply.
Clinical data
1. physical data
Chronic prostatitis case 120 example selecting here over-2014 years in 2012 medical.Be divided into treatment group and matched group at random, treatment group 60 example, age 26-61 year, average 42.2 years old; The course of disease 11 months-8 years, average 4.2 years; Matched group 60 example, age 26-60 year, average 42.8 years old; The course of disease 10 months-9 years, average 4.5 years.
Above patient's main clinical manifestation: urethral symptom refer to frequent micturition, urgent micturition, dysurea and the heeltap not to the utmost, drip after urine white; Local distending pain refers to perineal position distending pain or companion's lumbago and backache; General Symptoms finger is dizzy, weak, the symptoms such as insomnia.
Two groups of cases are all through body of prostate ultrasound diagnosis, and result all cases all has echo to change, skewness, and edge is irregular, prompting chronic prostatitis, and all cases per rectum refers to inspection, all points out chronic prostatitis;
Through statistical analysis, between two groups, the difference such as age, the state of an illness, the course of disease is little, has comparability.
2. diagnostic criteria
Press hydraulic fluid microscopy 3 according to patient's medical history, clinical symptoms, prostate palpation, prostate, possessing 2 persons can make a definite diagnosis.
Clinical symptoms:
1) paruria: urethral orifice adularescent mucoid secretions when frequent micturition, urgent micturition, dysurea, dribble of urine, urine end or stool, urethra scorching hot, scratchy and urinate not smooth (possessing more than 3);
2) local pain: perineum genital area, lower abdomen suprapubic region, lumbosacral region (at least one position continues more than 3 months).Prostate palpation (anus refers to inspection): Prostatic Surface is uneven, or asymmetric, and quality soft or hard is uneven, maybe can touch inflammatory tubercle, have local tenderness.Prostate is by hydraulic fluid microscopy: every high power field leukocyte is more than more than 10, and lecithin reduces or disappears.
3. Therapeutic Method
Treatment group: capsule prepared by the oral embodiment of the present invention 1, every day 2 times, each 4-6 grain.A course for the treatment of 4 Mondays, treat 2 courses for the treatment of continuously.
Matched group: oral QIANLIEKANG PIAN, every day 3 times, one time 3 ~ 4, continuously 2 courses for the treatment of of treatment.
4, criterion of therapeutical effect
According to chronic prostatitis criterion of therapeutical effect evaluation relevant in " disease clinical diagnosis and criterion of therapeutical effect ", cure: transference cure, 3 massage liquid inspections are all normal, B ultrasonic and digital rectal examination normal; Take a turn for the better: symptom is improved, massage liquid checks leukocyte < 10/HP, lecithin > 10/HP, and pyocyte disappears, and B ultrasonic and digital rectal examination show that mild inflammatory changes; Invalid: treatment before and after symptom, check unchanged.
5, therapeutic outcome
Two groups of comparitive study are in table 1.
Table 1 liang group comparitive study
Group Case load Cure (cure rate) Take a turn for the better (improvement rate) Invalid (inefficiency) Total effective rate
Matched group 60 8(13.3%) 40(66.7%) 12(20.0%) 80.0%
Treatment group 60 25(41.7%) 33(55.5%) 2(3.3%) 96.7%
Two groups are compared, and treatment group cure rate, total effective rate, be obviously better than matched group, has significant, have comparability (P < 0.05).Wherein matched group 8 cures patient, after drug withdrawal half a year, and recurrence 4 example; Treatment group 25 example cures patient, and after drug withdrawal half a year, no case was recurrence.Visible the present invention's treatment chronic prostatitis Chinese medicine composition is better than existing medicine QIANLIEKANG PIAN, and have cure rate high, the advantage do not recurred more, therapeutic effect is very remarkable.
Model case
Case 1: Wang, 50 years old, over nearly 1 year, often feel that the soreness of waist, urine are unclean, nocturia increased, and perineum and lower abdomen are done swollen, lustreless complexion, and white and greasy fur is thicker, and matter is light, and thready pulse chi is soft, is diagnosed as prostatitis; Take Chinese medicine composition of the present invention, two courses for the treatment of, its various transference cure, reaches criterion of cure, continues to strengthen and takes medicine 2 weeks, follows up a case by regular visits to half a year without recurrence.
Case 2: together certain, 65 years old, private prosecution suffers from chronic prostatitis 6 years, adopted various Therapeutic Method all invalid, urethral orifice adularescent mucoid secretions when cardinal symptom has frequent micturition, urgent micturition, dysurea, dribble of urine, urine end or defecates, the positions such as perineum genital area, lower abdomen suprapubic region, lumbosacral region, regular have pain.Take Chinese medicine composition of the present invention, two courses for the treatment of, its various symptom is clearly better, and continues 1 course for the treatment of of taking medicine, and its various transference cure, reaches criterion of cure, continues to strengthen and takes medicine 2 weeks, follows up a case by regular visits to half a year without recurrence.
Detailed description of the invention
The preparation of embodiment 1 capsule
Be prepared from by the Chinese crude drug of following portions by weight:
Preparation method:
(1), in above-mentioned prescription ratio each taste Chinese crude drug is accurately taken, for subsequent use.
(2), by Radix Sophorae Tonkinensis, Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Gardeniae, Fructus Liquidambaris grind respectively, add the purified water of medical material 8 times of weight, soak 1 hour, decoct 2 hours, filter; Filtering residue adds 5 times of water gagings, decocts 1 hour; Filter, merge twice filtrate; Concentrated filtrate, dry, pulverize into 80 object fine powders, for subsequent use.
(3), by Rhizoma Dioscoreae, Carapax Trionycis, the Radix Astragali, Radix Glycyrrhizae mixing, 80 object fine powders were ground into, for subsequent use.
(4), by step 3 and step 4 gained fine powder mix homogeneously, sterilizing, loads capsule, and every containing crude drug 0.4g.
The preparation of embodiment 2 tablet
Be prepared from by the Chinese crude drug of following portions by weight:
Preparation method:
(1), in above-mentioned prescription ratio each taste Chinese crude drug is accurately taken, for subsequent use.
(2), by Radix Sophorae Tonkinensis, Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Gardeniae, Fructus Liquidambaris grind respectively, add the purified water of medical material 10 times of weight, soak 2 hours, decoct 3 hours, filter; Filtering residue adds 5 times of water gagings, decocts 1 hour; Filter, merge twice filtrate; Concentrated filtrate, dry, pulverize into 80 object fine powders, for subsequent use.
(3), by Rhizoma Dioscoreae, Carapax Trionycis, the Radix Astragali, Radix Glycyrrhizae mixing, 80 object fine powders were ground into, for subsequent use.
(4), by step 3 and step 4 gained fine powder mix homogeneously, sterilizing, is prepared into tablet.
The preparation of embodiment 3 granule
Be prepared from by the Chinese crude drug of following portions by weight:
Preparation method:
(1), in prescription ratio each taste Chinese crude drug is accurately taken, for subsequent use.
(2), by Radix Sophorae Tonkinensis, Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Gardeniae, Fructus Liquidambaris grind respectively, add the purified water of medical material 8 times of weight, soak 0.5 hour, decoct 1 hour, filter; Filtering residue adds 3 times of water gagings, decocts 1 hour; Filter, merge twice filtrate; Concentrated filtrate, dry, pulverize into 80 object fine powders, for subsequent use.
(3), by Rhizoma Dioscoreae, Carapax Trionycis, the Radix Astragali, Radix Glycyrrhizae mixing, 80 object fine powders were ground into, for subsequent use.
(4), by step 3 and step 4 gained fine powder mix homogeneously, sterilizing is prepared into granule.
The preparation of embodiment 4 pill
Be prepared from by the Chinese crude drug of following portions by weight:
Preparation method:
(1), in prescription ratio each taste Chinese crude drug is accurately taken, for subsequent use.
(2), by Radix Sophorae Tonkinensis, Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Gardeniae, Fructus Liquidambaris grind respectively, add the purified water of medical material 5-10 times weight, soak 0.5-2 hour, decoct 1-3 hour, filter; Filtering residue adds 3-5 times of water gaging, decocts 1-3 hour; Filter, merge twice filtrate; Concentrated filtrate, dry, pulverize into 80 object fine powders, for subsequent use.
(3), by Rhizoma Dioscoreae, Carapax Trionycis, the Radix Astragali, Radix Glycyrrhizae mixing, 80 object fine powders were ground into, for subsequent use.
(4), by step 3 and step 4 gained fine powder mix homogeneously, sterilizing, adds refined honey, is prepared into pill.

Claims (4)

1. treat a Chinese medicine composition for chronic prostatitis, it is characterized in that, be prepared from by the Chinese crude drug of following portions by weight:
2. the Chinese medicine composition for the treatment of chronic prostatitis according to claim 1, is characterized in that, is prepared from by the Chinese crude drug of following portions by weight:
3. the Chinese medicine composition for the treatment of chronic prostatitis according to claim 1 and 2, is characterized in that preparation method comprises following steps:
(1) each taste Chinese crude drug is accurately taken in prescription ratio, for subsequent use;
(2) Radix Sophorae Tonkinensis, Semen Cuscutae, Fructus Schisandrae Chinensis, Fructus Gardeniae, Fructus Liquidambaris are ground respectively, add the purified water of medical material 5-10 times weight, soak 0.5-2 hour, decoct 1-3 hour, filter; Filtering residue adds 3-5 times of water gaging, decocts 1-3 hour; Filter, merge twice filtrate; Concentrated filtrate, dry, pulverize into 80 object fine powders, for subsequent use;
(3) by Rhizoma Dioscoreae, Carapax Trionycis, the Radix Astragali, Radix Glycyrrhizae mixing, 80 object fine powders were ground into, for subsequent use;
(4) by step (2) and step (3) gained fine powder mix homogeneously, sterilizing is prepared into solid dosage forms.
4. the Chinese medicine composition for the treatment of chronic prostatitis according to claim 1 and 2, is characterized in that, described Chinese medicine composition is tablet, powder, pill, granule or capsule.
CN201510081584.4A 2015-02-15 2015-02-15 One treats chronic prostatitis Chinese medicine composition Expired - Fee Related CN104547434B (en)

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