CN104547430B - Treat the instant particles as Chinese medicine and preparation method of infantile convulsion - Google Patents
Treat the instant particles as Chinese medicine and preparation method of infantile convulsion Download PDFInfo
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Abstract
The invention discloses a kind of instant particles as Chinese medicine for treating infantile convulsion, the primary raw material of following weight proportions is taken to be prepared：5 15 parts of cape jasmine, 10 20 parts of Angelica sinensis, 39 parts of Moschus, 37 parts of tortoiseshell, 15 parts of keel, 38 parts of Chinese yam, 15 parts of stiff silkworm, 5 15 parts of sweet wormwood, 4 10 parts of agaric, 26 parts of deep sea fish oil, 15 parts of indigo naturalis, 38 parts of pueraria lobata, 26 parts of arisaema cum bile, 8 15 parts of antelope's horn, complete 13 parts of worm, 7 12 parts of Artemisia anomala.Medicinal material medicine source of the present invention is easy to get, of low cost, and selected medicinal material is mostly the thing of mild in medicine property sum, and long-time service will not increase the burden in economy and body to user.
Description
Technical field
The present invention relates to traditional Chinese medicine field, more particularly to a kind of instant particles as Chinese medicine for treating infantile convulsion and preparation side
Method.
Background technology
Convulsions is the common acute disease of children, is more common in infant especially.Caused by many reasons make brain dysfunction.
It is in tatanic and clonic twitches to show as unexpected whole body or local muscle group, is often accompanied by the disturbance of consciousness.The morbidity of infantile convulsion
Rate is very high, and 5%~6% children once had one or many convulsions.Frequent convulsion breaking-out or persistent state threat to life can
Infant is left serious sequelae, influence Growth of Intelligence in Children and health.
The cause of disease：1. the age-based stage point：(1) neonatal period maternal infuries, suffocate, intracranial hemorrhage, septicemia, meningitis, broken wound
Wind and bilirubin encephalopathy are common.Sometimes it is also contemplated that brain growth defect, metabolic disorder, cytomegalic inclusion disease and toxoplasmosis
Deng.(2) infantile period high fever, convulsions, toxic encephalopathy, intracranial infection, tetany, infantile spasms are common.Sometimes
It should be noted that brain growth defect, brain injury sequela, drug poisoning, hypoglycemia etc..(3) Annual wool yield toxic encephalopathy, encephalic
Infection, epilepsy, poisoning are common.Sometimes notably intracranial spaceoccupying lesion and hypertensive encephalopathy etc..(4) the several normal of convulsions is caused
See disease hyperpyretic convulsion, intracranial infection, toxic encephalopathy, infantile spasms, hypoglycemia, hypomagnesemia, poisoning, hypocalcemia
Deng.2. the position point involved by lesion：The cause of disease of infantile convulsion is divided from the angle by the presence or absence of infection, can be divided into infectivity
It is (febrile convulsion) and non-infectious (no febrile convulsion).The position involved by lesion is divided into encephalic and two classes outside cranium.(1) it is infectious frightened
Fainting, (febrile convulsion) 1. intracranial disease virus infects such as viral encephalitis, encephalitis B.Bacterium infection such as purulent meningitis, knot
Nuclearity meningitis, brain abscess, Venous sinus thrombosis.Mycotic infection such as cryptococcal meningitis etc..Parasitic infection such as brain
Cysticercosis, encephalic malaria, cerebral schistosomiasis etc..2. the outer disease hyperpyretic convulsion of cranium, toxic encephalopathy (severe pneumonia, Poisoning
Dysentery, septicemia etc. are protopathy), lockjaw etc..(2) 1. intracranial disease craniocerebral injury is such as noninfectious convulsion (no febrile convulsion)
Maternal infuries, asphyxia neonatorum, intracranial hemorrhage.Big (small) deformity of encephalodysplasia such as congenital hydrocephalus, cerebrovascular malformation, head,
Cerebral palsy and neurocutaneous syndrome.Intracranial mass lesion such as brain tumor, capsules of brain swells.Epilepsy syndromes such as big breaking-out, baby
Youngster's spasm disease.Cerebral retrogressive venereal disease becomes such as demyelinating encephalopathy, cerebromacular degeneration.2. for example low blood calcium of the outer disease metabolic disease of cranium,
Hypoglycemia, hypomagnesemia, low blood sodium, hypernatremia, vitamin B1 or B6 deficiency diseases etc..Hereditary metabolic disorders disease such as glycogenic thesaurismosis, half
Lactose mass formed by blood stasis, phenylketonuria, hepatolenticular degeneration etc..Systemic disease such as hypertensive encephalopathy, uremia, arrhythmia, tight
Weight anaemia, food or drug and pesticide intoxication etc..
Clinical manifestation：1. faint from fear：Minority can have tendency before breaking-out：Extreme is irritated or " startles " frequently, nervous；Look
In terror, four limbs Muscle tensility increases suddenly；Breathing is rapid suddenly, pause or irregular；Body temperature rises sharply, complexion drastic change；Pupil size
Differ；Edge is uneven.Typical performance for unexpected onset, the loss of consciousness, head to layback, eyeball fix turn over or squint, mouth spit it is white
Foam, teeth clenched, face or limb muscle are in clonic spasm or tonic convulsion, and severe patient may occur in which neck rigidity, opisthotonos, exhale
Inhale not whole, livid purple or gatism.Several seconds duration is to several points or longer.Then it is transferred to drowsiness or comatose state.Sending out
Checked soon when making or after breaking-out, it is seen that mydriasis, light reflex are blunt, the sign such as pathologic reflex positive, after breaking-out stops
Soon consciousness recovery.When hypocalcemia is twitched, infant is it is realised that clear.If consciousness twitches or twitches repeatedly again before not yet recovering
Breaking-out is in persistent state person, and prompting is in a bad way, can be because of encephaledema, respiratory failure and death.Such as twitch position limitation and it is constant,
Often there is positioning meaning.Neonatal convulsions often show as the unformed changeable various each, abnormal operations of sample, such as apnea, no
Rule, two stare, paroxysmal is pale or cyanosis.Infant faints from fear only shows bicker, canthus twitch sometimes, and side limbs are twitched
Or both limbs are alternately twitched.It is few that neonatal convulsions show as systemic twitch person, and it is not whole or temporary often to show as respiratory rhythm
Stop, paroxysmal is livid purple or pale, and two are stared, nystagmus, and blink is acted or sucked, chew etc..2. convulsivus shape
State：Refer to convulsivus more than 30 minutes, or the intermittent phase consciousness of breaking-out twice cannot complete recuperator.For the Severe Type of convulsions.By
It can cause high fever, anoxic brain damage, encephaledema even hernia cerebri in convulsions overlong time.3. hyperpyretic convulsion：It is common in 6 months extremely
4 years old children, convulsions are how seldom continuous in a fever diseases to break out repeatedly, often in early stage of generating heat, short duration
The interior generation when fever 12 is small, consciousness recovery is fast after breaking-out, impassivity system positive sign, and heat is being moved back electroencephalogram after a week and recovered just
Often, pure hyperpyretic convulsion, prognosis bona are belonged to.Complex anal fistula age of onset is indefinite, often before 6 months or 6 years old with
After occur, be originally hyperpyretic convulsion, breaking-out for several times after low-heat even without heat when also faint from fear, recurrent exerbation is multiple sometimes, one
The secondary convulsions time is longer, and more than 15 minutes, still to be abnormal after convulsive attack 2 weeks, prognosis was poor for EEG(electrocardiogram) examination.It is changed into insane
The possibility of epilepsy is 15%~30%.
In the Chinese medicine of existing treatment infantile convulsion, 103239640 A (application numbers of application publication number CN
201310178079.2) patent document discloses a kind of Chinese herbal granules for treating infantile convulsion, takes following weight proportions
Primary raw material is prepared：3-7 parts of kaladana, 3-7 parts of rheum officinale, 3-7 parts of peppermint, 3-7 parts of Fructus Forsythiae, 4-8 parts of Ligusticum wallichii, radix scutellariae 4-8
Part, 7-12 parts of Cortex Phellodendri, 7-12 parts of amber, 7-12 parts of pearl, 0.5-3 parts of bulbus fritillariae cirrhosae, 7-12 parts of fushen, 7-12 parts of evodia rutaecarpa, ox
It is 3-7 parts yellow, 3-7 parts of dayflower, 3-7 parts of bamboo juice.103800584 A of application publication number CN (application number 201410082408.8)
Patent document disclose a kind of Chinese medicine composition for treating infantile convulsion, it is characterized in that：By the bulk pharmaceutical chemicals system of following parts by weight
Into：6-8 parts of cordate houttuynia, 6-8 parts of five-leaved chaste tree, 6-8 parts of gypsum, 6-8 parts of honeysuckle, 2-4 parts of cinnabar, 2-4 parts of uncaria, 2-4 parts of stiff silkworm,
2-4 parts of rhizoma arisaematis, 2-4 parts of raddle, 1-2 parts of radix glycyrrhizae, 1-2 parts of crotons, 0.3-0.7 parts of Moschus.
It can be seen from the above that Chinese medicine occupies very important status in terms of infantile convulsion is treated, but in patent document, do not have
The preferable instant particles as Chinese medicine for being used to treat infantile convulsion.
The content of the invention
In view of the deficiencies of the prior art, it is an object of the present invention to providing the instant particles as Chinese medicine for the treatment of infantile convulsion, this
Invention medicinal material medicine source is easy to get, of low cost, and selected medicinal material is mostly the thing of mild in medicine property sum, and Chinese medicine and the food materials nourished are combined one
The electuary being prepared into is acted, long-time service will not increase the burden in economy and body to user.
Another object of the present invention is just to provide the preparation method of above-mentioned instant particles as Chinese medicine.
The technical scheme is that：
The instant particles as Chinese medicine of infantile convulsion is treated, takes the primary raw material of following weight proportions to be prepared：5-15 parts of cape jasmine, when
Return 10-20 parts, 3-9 parts of Moschus, 3-7 parts of tortoiseshell, 1-5 parts of keel, 3-8 parts of Chinese yam, 1-5 parts of stiff silkworm, 5-15 parts of sweet wormwood, agaric 4-
10 parts, 2-6 parts of deep sea fish oil, 1-5 parts of indigo naturalis, 3-8 parts of pueraria lobata, 2-6 parts of arisaema cum bile, 8-15 parts of antelope's horn, full worm 1-3 parts, Liu
Post 7-12 parts of slave.
The instant particles as Chinese medicine of infantile convulsion is treated, preferable scheme is that the primary raw material for taking following weight proportions is prepared：
8-13 parts of cape jasmine, 13-18 parts of Angelica sinensis, 5-7 parts of Moschus, 4-6 parts of tortoiseshell, 2-4 parts of keel, 4-7 parts of Chinese yam, 2-4 parts of stiff silkworm, sweet wormwood
8-13 parts, 6-8 parts of agaric, 3-5 parts of deep sea fish oil, 2-4 parts of indigo naturalis, 4-7 parts of pueraria lobata, 3-5 parts of arisaema cum bile, 10-13 parts of antelope's horn,
Full 1.5-2.5 parts of worm, 9-11 parts of Artemisia anomala.
The instant particles as Chinese medicine of infantile convulsion is treated, the scheme being more highly preferred to is prepared by the primary raw material for taking following weight proportions
Form：10 parts of cape jasmine, 15 parts of Angelica sinensis, 6 parts of Moschus, 5 parts of tortoiseshell, 3 parts of keel, 5.5 parts of Chinese yam, 3 parts of stiff silkworm, 10 parts of sweet wormwood, wood
7 parts of ear, 4 parts of deep sea fish oil, 3 parts of indigo naturalis, 5 parts of pueraria lobata, 4 parts of arisaema cum bile, 11 parts of antelope's horn, complete 2 parts of worm, 10 parts of Artemisia anomala.
The preparation method of above-mentioned instant particles as Chinese medicine, step are as follows：
(1) keel and antelope's horn are broken into pieces and is together placed in container with tortoiseshell, it is crisp in forging on smokeless stove fire, after cooling
Smalls is ground into, crosses 80-120 mesh sieves；
(2) wheat bran is crossed into 120-160 mesh sieves, in the hot pot that the wheat bran shone input is dryouied, treats that wheat bran is fried to 60-70 DEG C
When put into cape jasmine, Angelica sinensis, Moschus and stiff silkworm, stir-frying that will be repeatedly during frying and with slow boiling, frying 5-10 minutes,
Wheat bran is weeded out, the cape jasmine fried, Angelica sinensis, Moschus and stiff silkworm are ground into smalls；
(3) Chinese yam is cut into the block of coin-size, agaric is cleaned, filament is cut into and is mixed with Chinese yam block, is placed on food steamer
The sweet wormwood silk cut is added after steaming 20-40 minutes, is steamed again 5-15 minutes, is ground into the Chinese yam block steamed with rolling pin
Thick paste, by thick paste and micro-wave oven, toasts 2-5 minutes, dries in the air cool stand-by；
(4) pueraria lobata, arisaema cum bile, full worm and Artemisia anomala are added water to cook twice, first time water consumption for pueraria lobata, arisaema cum bile,
Full worm and 2-4 times of Artemisia anomala gross weight, big fire is decocted to boiling, is waited to seethe with excitement and is filtered after five minutes, obtains filtrate 1, filter residue adds again
Water small fire is simmered 50-70 minutes slowly, is changed big fire and is decocted 3-8 minutes, and filtering, obtains filtrate 2, filtrate 1 and filtrate 2 are mixed, and stands 2-6
Hour, obtain supernatant；
(5) supernatant small fire obtained by step (4) is decocted to boiling slowly and adds medicine obtained by step (1)-(3), with chopsticks one
Side decocts while stirring addition deep sea fish oil and indigo naturalis to after melting completely, addition thick paste weight when abundant concentration is thick paste
1.2 times of honey, ceases fire after mixing, thick paste is placed on iron plate, and small fire is dried 8-14 minutes slowly, obtains drying object, drying object is pressed
Electuary is prepared into according to every 2-4 grams of bag.
The preparation method of above-mentioned instant particles as Chinese medicine, step (1) are ground into smalls after cooling, cross 90-110 mesh sieves and (preferably, put
Smalls is ground into after cool, crosses 100 mesh sieves).
The preparation method of above-mentioned instant particles as Chinese medicine, step (2) put into when wheat bran is fried to 63-68 DEG C cape jasmine, Angelica sinensis, Moschus and
Stiff silkworm (preferable, cape jasmine, Angelica sinensis, Moschus and stiff silkworm are put into when wheat bran is fried to 65 DEG C).
The preparation method of above-mentioned instant particles as Chinese medicine, stir-frying that will be repeatedly during step (2) frying and with slow boiling are fried
(preferable, stir-frying that will be repeatedly during frying and with slow boiling, frying 8 minutes) 6-9 minutes processed.
The preparation method of above-mentioned instant particles as Chinese medicine, step (3) is placed on food steamer steam 25-35 minutes after add the sweet wormwood cut
Silk, steams 8-13 minutes and (preferably, is placed on food steamer after steaming 30 minutes the sweet wormwood silk for adding and cutting, steams 10 again again
Minute).
The preparation method of above-mentioned instant particles as Chinese medicine, step (4) first time water consumption are pueraria lobata, arisaema cum bile, full worm and Artemisia anomala
2.5-3.5 times (preferable, first time water consumption is 3 times of pueraria lobata, arisaema cum bile, full worm and Artemisia anomala gross weight) of gross weight.
The preparation method of above-mentioned instant particles as Chinese medicine, step (4) mix filtrate 1 and filtrate 2, when standing 3-5 is small (it is preferable,
Filtrate 1 and filtrate 2 are mixed, when standing 4 is small).
Optimal use method：To make the present invention reach optimal therapeutic effect, manufactured instant particles as Chinese medicine is later half small in breakfast, lunch and dinner
When take, every time 1 bag, boiling water, which is washed open, to be taken.
The pharmacological effect of each bulk pharmaceutical chemicals is respectively：
Cape jasmine：Heat-clearing, purging intense heat, cool blood.Pyreticosis restlessness of asrhenia type and insomnia is controlled, jaundice, gonorrhoea, quenches one's thirst, hot eyes, pharyngalgia, spits blood, nosebleed
Blood, bloody flux, hematuria, pathopyretic ulcer, sprains swelling and pain.
Angelica sinensis：Enrich blood；Promoting blood circulation；Menstruction regulating and pain relieving；Moisturize laxation.The main all cards of the deficiency of blood；Irregular menstruation；Amenorrhea；Dysmenorrhoea；Abdominal mass knot
It is poly-；Uterine bleeding；Asthenia cold abdominalgia；Impotence numbness；Numbness；Intestines are dry and shit is difficult；Weight after dysentery characterized by blood in the stool；Ulcer sores；Injury from falling down.
Moschus：Lead to all keys, open channels and collaterals, saturating flesh bone, relieving alcoholism, disappear melon and fruit dyspepsia.Control apoplexy, middle gas, middle evil, coma due to blocking of the respiratory system, product
Poly- abdominal mass.
Tortoiseshell：Enriching yin, checking exuberance of yang, kidney tonifying, strong bone.Cure mainly：The deficiency of the kidney yin is controlled, hectic fever due to yin labor heat, spits blood, bleeding from five sense organs or subcutaneous tissue, chronic cough, loses
Essence, uterine bleeding, with, pain in the back, the atrophic debility of bones, wind formation from yin deficiency, protracted dysentery, chronic malaria, hemorrhoid, non-closure of fontanels jin infants.
Keel：Base：It is ancient times mammal as the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex, ox class, deer class etc..Component：
The main calcium carbonate of keel and calcium phosphate, still containing iron, potassium, sodium, chlorine, sulfate radical etc..Pharmacological property：Puckery, sweet and neutral.The thoughts of returning home, liver, kidney,
Large intestine channel.Function cures mainly：Tranquilizing mind, it is calming the liver, restrain astringent method.Palpitaition is cured mainly, seized with terror swollen, insomnia, forgetful, frightened epilepsy is demented,
Dizziness, spontaneous sweating, the enuresis of passing out semen, under uterine bleeding band, chronic diarrhea and dysentery, ulcer does not close up long and wet sore.
Antelope's horn：Base：For the angle of Bovidae antelope category animal sahilite.Component：Sahilite angle contains keratin, phosphoric acid
Calcium, insoluble inorganic salts, lysine, serine, glutamic acid, phenylalanine, leucine, aspartic acid etc..Pharmacological property：It is salty, tremble with fear.Return
Liver, the heart channel of Hang-Shaoyin.Function cures mainly：It is calming the liver to stop the wind, clear liver and improve vision, blood-cleaning detoxifying.Cure mainly liver wind agitation, twitch, muscle arteries and veins contraction；Liver
Positive dizziness of having a headache, irascibility red eye, swell pain and blood-head bleeding, warm disease hair spot, carbuncle sore tumefacting virus.
Chinese yam：Have nourish it is strong, it is aid digestion, hold back abnormal sweating, the effect of antidiarrheal, cure mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes
Quench one's thirst, oliguria frequency, seminal emission, women is with lower and dyspeptic chronic enteritis.
Stiff silkworm：Dispelling wind and relieving convulsion, reducing phlegm and resolving masses.(reducing phlegm and resolving masses of relieving convulsion and spasm wind-expelling pain-stopping) is used for convulsion, and throat swells
Bitterly, submandibular lymph nodes is scorching, facioplegia, pruitus.(1) relieve dizziness, high fever, infantile convulsions, epilepsy, etc. spasmolysis：For headache, dizziness caused by liver wind agitation
Disease, twitch.And it is used for headache due to pathogenic wind-heat and itchy skin eruption.(2) reducing phlegm and resolving masses：For scrofula, tonsillitis, parotitis.(3) polarization
Intermittent headache, collet wind, two temple pain.
Sweet wormwood：Sweet wormwood decocting liquid has staphylococcus epidermis, micrococcus catarrhalis, bacillus anthracis, corynebacterium diphtheriae stronger antibacterial
Effect, also has certain inhibitory action to staphylococcus aureus, Pseudomonas aeruginosa, shigella dysenteriae, tuberculosis stalk bacterium etc..Sweet wormwood volatilizees
Oil has bacteriostasis in 0.25% concentration to all dermatophytes, in 1% concentration, has sterilization to make to all dermatophytes
With.Sweet wormwood is known as the effect of resisiting influenza virus.Sodium artesunate to golden grape, shigella flexneri, Escherichia coli, micrococcus catarrhalis,
A type and paratyphoid B stalk bacterium have certain antibacterial action.Sitosterol and stigmasterol in sweet wormwood also have antivirus action.
Qinghaosu can reducing heart rate, suppress myocardial contractive power, reduce coronary flow.Intravenous injection has antihypertensive effect, but does not influence
The booster reaction of methylepinephrine, it is believed that main system suppresses to be changed to the direct of heart.
Agaric：Agaric, Chinese medicine name.For Mycophyta Auriculariaceae plant agaric Auricularia auricular (L.)
Underw. fructification.The ground such as it is distributed in.With the effect of benefiting qi and nourishing blood, moistening lung, stops blooding, decompression, anticancer.It is usually used in the deficiency of vital energy
Anemia, four limbs are twitched, chronic cough of deficiency lung, are spat blood, and are spitted blood, bleeding from five sense organs or subcutaneous tissue, bloody flux, hemorrhoid hemorrhage, woman uterine bleeding, high blood pressure, constipation, eye
Bottom bleeding, sub- Cervical cancer, carcinoma of vagina, traumatic injury.
Deep sea fish oil：1st, blood fat is adjusted, clears up thrombus, prevents blood clotting, prevention cerebral thrombus, cerebral hemorrhage and apoplexy.2、
Prevent arthritis, alleviate gout, asthma, respite swells and ache as caused by arthritis.3rd, prevention senile dementia, nutrition are big
Brain, improve memory.4th, eyesight, prevention presbyopia are improved.5th, retina is safeguarded.
Indigo naturalis：Indigo naturalis, Chinese medicine name.For rank of nobility dinner party section plant acanthaceous indigo, polygonaceae plant indigo plant, cruciferae isatis leaf
Or cauline leaf processed obtained dried powder, agglomerate or particle.Has the effect such as clearing heat and detoxicating, blood cooling and ecchymoses removing, purging intense heat arresting convulsion, in Gu
In generation, is also commonly used for printing and dyeing cloth, thrush etc..Main product is in Fujian, Yunnan, Jiangsu and other places.Nature and flavor are salty-cold, have clearing heat and detoxicating, and cool blood disappears
Spot, purging intense heat arresting convulsion and other effects.It is mainly used for warm disease excess heat, and macula, spits blood, spitting of blood, pharyngalgia aphtha, pediatric epilepsy scared, and sore swells are red
Poison, snakebite and bugbite etc..
Pueraria lobata：Pueraria lobata, Chinese medicine name.For the dry root of legume pueraria lobata, practise and claim elegant jessamine.Autumn, the excavation of two season of winter, take advantage of fresh-cut
Into sheet or fritter；It is dry.It is sweet, pungent, it is cool.There is expelling pathogenic factors from muscles and skin to bring down a fever, promoting eruption, promotes the production of body fluid to quench thirst, the work(of Shengyang Zhixie.It is usually used in exterior syndrome hair
Heat, stiff nape and back, measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea.
Arisaema cum bile：Clearing away fire and eliminating phlegm, it is relieving convulsion fixed chronic.Stroke and phlegm confusing heart, infantile convulsion epilepsy are controlled, convulsive seizure due to phlegm-fire asthma is coughed, phlegm-accumulating vertigo.
Full worm：Ceases wind antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation.For liver wind agitation, spasm twitch, child convulsion, middle air port, hemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.
Artemisia anomala：Also known as Artemisia anomala grass, Herba Senecionis Scandentis, for the wounded in the battle herb of composite family sagebruss artemisia anomalas.Pharmacological property：Stem cylinder
Shape, surface brown color or brown-green, matter is hard and crisp, frangibility, and capitulum integrates spike panicle, and withered yellow, gas is fragrant,
It is bitter, pungent, it is warm-natured.Component：Mainly contain arteanoflavone, tricin, apiolin, palmitic acid etc..According to modern pharmacological research
It was found that the medical instrument has the effect of anti anoxia, promoting blood circulation and removing blood stasis, disperse accumulation, hemostasia and detumescence, for amenorrhea due to stagnation of blood, dyspeptic abdominalgia, hematuria,
The diseases such as scald.
1st, instant particles as Chinese medicine " focusing on overall " of the present invention, can not only treat infantile convulsion, but also can promote to sleep, and most importantly will
Chinese medicine and the food materials of nourishing are combined, this is the big feature for being different from drug therapy, the complete basis of this instant particles as Chinese medicine
Traditional Chinese medicine principle is prepared, more securely and reliably, without any side effects, to matrix without any stimulation.
2nd, instant particles as Chinese medicine of the present invention for Chinese medicine and nourishes the preparation of food materials combination, has a qi and activate blood circulation, anticonvulsant effect,
It is the current treatment most effective medicine of infantile convulsion, and has unique curative effect to diseases such as children anorexia and constipation.
3rd, medicinal material compatibility is suitable selected by Chinese medicine preparation of the present invention, is made of modern advanced pharmaceutical technology, evident in efficacy,
Safe without toxic side effect, treats both principal and secondary aspect of disease, and should be widely promoted application.
Embodiment
With reference to embodiment and the experimental example technical solution that the present invention will be described in detail, but protection domain is not limited by this.
Embodiment 1 treats the instant particles as Chinese medicine of infantile convulsion, takes the primary raw material of following weight proportions to be prepared that (every part takes
10g)：5 parts of cape jasmine, 10 parts of Angelica sinensis, 3 parts of Moschus, 3 parts of tortoiseshell, 1 part of keel, 3 parts of Chinese yam, 1 part of stiff silkworm, 5 parts of sweet wormwood, agaric 4
Part, 2 parts of deep sea fish oil, 1 part of indigo naturalis, 3 parts of pueraria lobata, 2 parts of arisaema cum bile, 8 parts of antelope's horn, complete 1 part of worm, 7 parts of Artemisia anomala.
The preparation method of above-mentioned instant particles as Chinese medicine, step are as follows：
(1) keel and antelope's horn are broken into pieces and is together placed in container with tortoiseshell, it is crisp in forging on smokeless stove fire, after cooling
Smalls is ground into, crosses 80 mesh sieves；
(2) wheat bran is crossed into 120 mesh sieves, in the hot pot that the wheat bran shone input is dryouied, is put into when wheat bran is fried to 60 DEG C
Cape jasmine, Angelica sinensis, Moschus and stiff silkworm, stir-frying that will be repeatedly during frying and with slow boiling, frying 5 minutes, weeds out wheat bran,
The cape jasmine fried, Angelica sinensis, Moschus and stiff silkworm are ground into smalls；
(3) Chinese yam is cut into the block of coin-size, agaric is cleaned, filament is cut into and is mixed with Chinese yam block, is placed on food steamer
The sweet wormwood silk for adding cut after twenty minutes is steamed, is steamed again 5 minutes, the Chinese yam block steamed is ground into thick paste with rolling pin,
By in thick paste and micro-wave oven, toast 2 minutes, dry in the air cool stand-by；
(4) pueraria lobata, arisaema cum bile, full worm and Artemisia anomala are added water to cook twice, first time water consumption for pueraria lobata, arisaema cum bile,
Full worm and 2 times of Artemisia anomala gross weight, big fire is decocted to boiling, is treated that boiling is filtered after five minutes, is obtained filtrate 1, filter residue adds water again
Small fire is simmered 50 minutes slowly, is changed big fire and is decocted 3 minutes, and filtering, obtains filtrate 2, filtrate 1 and filtrate 2 are mixed, and when standing 2 is small, obtains
Clear liquid；
(5) supernatant small fire obtained by step (4) is decocted to boiling slowly and adds medicine obtained by step (1)-(3), with chopsticks one
Side decocts while stirring addition deep sea fish oil and indigo naturalis to after melting completely, addition thick paste weight when abundant concentration is thick paste
1.2 times of honey, ceases fire after mixing, thick paste is placed on iron plate, and small fire is dried 8 minutes slowly, drying object is obtained, by drying object according to every
2 grams of bag is prepared into electuary.
Model case one：Thunder XX, man, 1 years old, be people from Qufu, and in January, 2012 morbidity, faints from fear one month, eyeball occurs and turns
Dynamic, eyes direct-view or the symptom turned over, flushed face, and do not suck the breast usually it is unprovoked cry, faint from fear 7-8 times daily, and
Sleep convulsions amount is more and more every time, and it is invalid that infusion is had an injection, and doctor suggests treating in infantile convulsion using present invention gained
Medicine electuary.
Using 1 gained instant particles as Chinese medicine of the present embodiment, Chinese medicine composition of the present invention is taken after 3 days, patient's recovery from illness.
Embodiment 2 treats the instant particles as Chinese medicine of infantile convulsion, takes the primary raw material of following weight proportions to be prepared that (every part takes
5g)：15 parts of cape jasmine, 20 parts of Angelica sinensis, 9 parts of Moschus, 7 parts of tortoiseshell, 5 parts of keel, 8 parts of Chinese yam, 5 parts of stiff silkworm, 15 parts of sweet wormwood, agaric 10
Part, 6 parts of deep sea fish oil, 5 parts of indigo naturalis, 8 parts of pueraria lobata, 6 parts of arisaema cum bile, 15 parts of antelope's horn, complete 3 parts of worm, 12 parts of Artemisia anomala.
The preparation method of above-mentioned instant particles as Chinese medicine, step are as follows：
(1) keel and antelope's horn are broken into pieces and is together placed in container with tortoiseshell, it is crisp in forging on smokeless stove fire, after cooling
Smalls is ground into, crosses 120 mesh sieves；
(2) wheat bran is crossed into 160 mesh sieves, in the hot pot that the wheat bran shone input is dryouied, is put into when wheat bran is fried to 70 DEG C
Cape jasmine, Angelica sinensis, Moschus and stiff silkworm, stir-frying that will be repeatedly during frying and with slow boiling, frying 10 minutes, weeds out bran
Skin, smalls is ground into by the cape jasmine fried, Angelica sinensis, Moschus and stiff silkworm；
(3) Chinese yam is cut into the block of coin-size, agaric is cleaned, filament is cut into and is mixed with Chinese yam block, is placed on food steamer
The sweet wormwood silk cut is added after steaming 20-40 minutes, is steamed again 15 minutes, is ground into the Chinese yam block steamed with rolling pin thick
Cream, by thick paste and micro-wave oven, toasts 5 minutes, dries in the air cool stand-by；
(4) pueraria lobata, arisaema cum bile, full worm and Artemisia anomala are added water to cook twice, first time water consumption for pueraria lobata, arisaema cum bile,
Full worm and 4 times of Artemisia anomala gross weight, big fire is decocted to boiling, is treated that boiling is filtered after five minutes, is obtained filtrate 1, filter residue adds water again
Small fire is simmered 70 minutes slowly, is changed big fire and is decocted 8 minutes, and filtering, obtains filtrate 2, filtrate 1 and filtrate 2 are mixed, and when standing 6 is small, obtains
Clear liquid；
(5) supernatant small fire obtained by step (4) is decocted to boiling slowly and adds medicine obtained by step (1)-(3), with chopsticks one
Side decocts while stirring addition deep sea fish oil and indigo naturalis to after melting completely, addition thick paste weight when abundant concentration is thick paste
1.2 times of honey, ceases fire after mixing, thick paste is placed on iron plate, and small fire is dried 14 minutes slowly, obtains drying object, by drying object according to
Often wrap 4 grams and be prepared into electuary.
Embodiment 3 treats the instant particles as Chinese medicine of infantile convulsion, takes the primary raw material of following weight proportions to be prepared that (every part takes
15g)：8 parts of cape jasmine, 13 parts of Angelica sinensis, 5 parts of Moschus, 4 parts of tortoiseshell, 2 parts of keel, 4 parts of Chinese yam, 2 parts of stiff silkworm, 8 parts of sweet wormwood, agaric 6
Part, 3 parts of deep sea fish oil, 2 parts of indigo naturalis, 4 parts of pueraria lobata, 3 parts of arisaema cum bile, 10 parts of antelope's horn, complete 1.5 parts of worm, 9 parts of Artemisia anomala.
The preparation method of instant particles as Chinese medicine is stated, step is as follows：
(1) keel and antelope's horn are broken into pieces and is together placed in container with tortoiseshell, it is crisp in forging on smokeless stove fire, after cooling
Smalls is ground into, crosses 90 mesh sieves；
(2) wheat bran is crossed into 130 mesh sieves, in the hot pot that the wheat bran shone input is dryouied, is put into when wheat bran is fried to 63 DEG C
Cape jasmine, Angelica sinensis, Moschus and stiff silkworm, stir-frying that will be repeatedly during frying and with slow boiling, frying 6 minutes, weeds out wheat bran,
The cape jasmine fried, Angelica sinensis, Moschus and stiff silkworm are ground into smalls；
(3) Chinese yam is cut into the block of coin-size, agaric is cleaned, filament is cut into and is mixed with Chinese yam block, is placed on food steamer
The sweet wormwood silk cut is added after steaming 25 minutes, is steamed again 8 minutes, the Chinese yam block steamed is ground into thick paste with rolling pin,
By in thick paste and micro-wave oven, toast 3 minutes, dry in the air cool stand-by；
(4) pueraria lobata, arisaema cum bile, full worm and Artemisia anomala are added water to cook twice, first time water consumption for pueraria lobata, arisaema cum bile,
Full worm and 2.5 times of Artemisia anomala gross weight, big fire is decocted to boiling, is treated that boiling is filtered after five minutes, is obtained filtrate 1, filter residue adds again
Water small fire is simmered 55 minutes slowly, is changed big fire and is decocted 4 minutes, and filtering, obtains filtrate 2, filtrate 1 and filtrate 2 are mixed, and when standing 3 is small, obtains
Supernatant；
(5) supernatant small fire obtained by step (4) is decocted to boiling slowly and adds medicine obtained by step (1)-(3), with chopsticks one
Side decocts while stirring addition deep sea fish oil and indigo naturalis to after melting completely, addition thick paste weight when abundant concentration is thick paste
1.2 times of honey, ceases fire after mixing, thick paste is placed on iron plate, and small fire is dried 10 minutes slowly, obtains drying object, by drying object according to
Often wrap 2.5 grams and be prepared into electuary.
Model case two：Qiu XX, female are 8 months big.Qufu City, Shandong Province city personage, in April, 2013 morbidity, faints from fear 10 days, face
Rubescent and the symptom of apocleisis occur, eyelid slightly twitches and with the pico- twitch of face, livid purple around lip, takes medicine and beats
Pin is invalid, so doctor suggests treating the instant particles as Chinese medicine of infantile convulsion using present invention gained.
Using 3 gained instant particles as Chinese medicine of the present embodiment, to take 2 days, body progressively recovers, and takes this Chinese medicine and twitches reduction in 3 days,
Fully recover after taking this Chinese medicine after five days.
Embodiment 4 treats the instant particles as Chinese medicine of infantile convulsion, takes the primary raw material of following weight proportions to be prepared that (every part takes
20g)：13 parts of cape jasmine, 18 parts of Angelica sinensis, 7 parts of Moschus, 6 parts of tortoiseshell, 4 parts of keel, 7 parts of Chinese yam, 4 parts of stiff silkworm, 13 parts of sweet wormwood, agaric 8
Part, 5 parts of deep sea fish oil, 4 parts of indigo naturalis, 7 parts of pueraria lobata, 5 parts of arisaema cum bile, 13 parts of antelope's horn, complete 2.5 parts of worm, 11 parts of Artemisia anomala.
The preparation method of above-mentioned instant particles as Chinese medicine, step are as follows：
(1) keel and antelope's horn are broken into pieces and is together placed in container with tortoiseshell, it is crisp in forging on smokeless stove fire, after cooling
Smalls is ground into, crosses 110 mesh sieves；
(2) wheat bran is crossed into 150 mesh sieves, in the hot pot that the wheat bran shone input is dryouied, is put into when wheat bran is fried to 68 DEG C
Cape jasmine, Angelica sinensis, Moschus and stiff silkworm, stir-frying that will be repeatedly during frying and with slow boiling, frying 9 minutes, weeds out wheat bran,
The cape jasmine fried, Angelica sinensis, Moschus and stiff silkworm are ground into smalls；
(3) Chinese yam is cut into the block of coin-size, agaric is cleaned, filament is cut into and is mixed with Chinese yam block, is placed on food steamer
The sweet wormwood silk cut is added after steaming 35 minutes, is steamed again 13 minutes, the Chinese yam block steamed is ground into thick paste with rolling pin,
By in thick paste and micro-wave oven, toast 4 minutes, dry in the air cool stand-by；
(4) pueraria lobata, arisaema cum bile, full worm and Artemisia anomala are added water to cook twice, first time water consumption for pueraria lobata, arisaema cum bile,
Full worm and 3.5 times of Artemisia anomala gross weight, big fire is decocted to boiling, is treated that boiling is filtered after five minutes, is obtained filtrate 1, filter residue adds again
Water small fire is simmered 65 minutes slowly, is changed big fire and is decocted 7 minutes, and filtering, obtains filtrate 2, filtrate 1 and filtrate 2 are mixed, and when standing 5 is small, obtains
Supernatant；
(5) supernatant small fire obtained by step (4) is decocted to boiling slowly and adds medicine obtained by step (1)-(3), with chopsticks one
Side decocts while stirring addition deep sea fish oil and indigo naturalis to after melting completely, addition thick paste weight when abundant concentration is thick paste
1.2 times of honey, ceases fire after mixing, thick paste is placed on iron plate, and small fire is dried 12 minutes slowly, obtains drying object, by drying object according to
Often wrap 3.5 grams and be prepared into electuary.
Embodiment 5 treats the instant particles as Chinese medicine of infantile convulsion, takes the primary raw material of following weight proportions to be prepared that (every part takes
30g)：10 parts of cape jasmine, 15 parts of Angelica sinensis, 6 parts of Moschus, 5 parts of tortoiseshell, 3 parts of keel, 5.5 parts of Chinese yam, 3 parts of stiff silkworm, 10 parts of sweet wormwood, wood
7 parts of ear, 4 parts of deep sea fish oil, 3 parts of indigo naturalis, 5 parts of pueraria lobata, 4 parts of arisaema cum bile, 11 parts of antelope's horn, complete 2 parts of worm, 10 parts of Artemisia anomala.
The preparation method of above-mentioned instant particles as Chinese medicine, step are as follows：
(1) keel and antelope's horn are broken into pieces and is together placed in container with tortoiseshell, it is crisp in forging on smokeless stove fire, after cooling
Smalls is ground into, crosses 100 mesh sieves；
(2) wheat bran is crossed into 140 mesh sieves, in the hot pot that the wheat bran shone input is dryouied, is put into when wheat bran is fried to 65 DEG C
Cape jasmine, Angelica sinensis, Moschus and stiff silkworm, stir-frying that will be repeatedly during frying and with slow boiling, frying 7 minutes, weeds out wheat bran,
The cape jasmine fried, Angelica sinensis, Moschus and stiff silkworm are ground into smalls；
(3) Chinese yam is cut into the block of coin-size, agaric is cleaned, filament is cut into and is mixed with Chinese yam block, is placed on food steamer
The sweet wormwood silk cut is added after steaming 30 minutes, is steamed again 10 minutes, the Chinese yam block steamed is ground into thick paste with rolling pin,
By in thick paste and micro-wave oven, toast 3 minutes, dry in the air cool stand-by；
(4) pueraria lobata, arisaema cum bile, full worm and Artemisia anomala are added water to cook twice, first time water consumption for pueraria lobata, arisaema cum bile,
Full worm and 3 times of Artemisia anomala gross weight, big fire is decocted to boiling, is treated that boiling is filtered after five minutes, is obtained filtrate 1, filter residue adds water again
Small fire is simmered 60 minutes slowly, is changed big fire and is decocted 6 minutes, and filtering, obtains filtrate 2, filtrate 1 and filtrate 2 are mixed, and when standing 4 is small, obtains
Clear liquid；
(5) supernatant small fire obtained by step (4) is decocted to boiling slowly and adds medicine obtained by step (1)-(3), with chopsticks one
Side decocts while stirring addition deep sea fish oil and indigo naturalis to after melting completely, addition thick paste weight when abundant concentration is thick paste
1.2 times of honey, ceases fire after mixing, thick paste is placed on iron plate, and small fire is dried 11 minutes slowly, obtains drying object, by drying object according to
Often wrap 3 grams and be prepared into electuary.
The clinical practice of the instant particles as Chinese medicine of the gained treatment infantile convulsion of 1 embodiment of test example 5：We have randomly selected 400
Name patient tests (400 infantile convulsion patients), is divided into experimental group and control group, wherein women 200, male 200
Example.2 days before experiment, which is continuously observed, records symptom and change, is randomly divided into two groups, experimental group and control
Group, experimental group use 5 products obtained therefrom of embodiment, and control group takes the medicine of other treatment infantile convulsion.
Efficacy evaluation：)：1st, cure, after drug administration, malaise symptoms are wholly absent；2nd, effectively, it is uncomfortable after drug administration
Symptom mitigates or partial disappearance；3rd, invalid, after drug administration, malaise symptoms are unchanged.
5 days time limits are observed, every observation in 1 day once, records and counts the improvement situation of all patient symptoms.
Experimental result：
Experimental group：It is effective 196 (98%) in 200 patients, effective 4 (2%), invalid 0, total effective rate 100%,
All patients react without any discomfort within the observation period.
Control group：Effective 130 (65%) in 200 patients, effective 50 (25%), invalid 20 (10%), always have
Efficiency 90%, has 20 (10%) patients convulsions number occur within the observation period and adverse reaction, 40 (20%) patients such as increases
Appearance such as vomits at the malaise symptoms.
Self-induction symptom and its muscle power spirit change are as shown in table 1 during use.
Table 1：
Therapeutic effect：Instant particles as Chinese medicine therapeutic effect of the present invention is substantially better than control group, and during use, no one occurs uncomfortable
Symptom or side effect.
Claims (9)
1. treat the preparation method of the instant particles as Chinese medicine of infantile convulsion, it is characterised in that：Take the raw material of following weight proportions：Cape jasmine 5-
15 parts, 10-20 parts of Angelica sinensis, 3-9 parts of Moschus, 3-7 parts of tortoiseshell, 1-5 parts of keel, 3-8 parts of Chinese yam, 1-5 parts of stiff silkworm, sweet wormwood 5-15
Part, 4-10 parts of agaric, 2-6 parts of deep sea fish oil, 1-5 parts of indigo naturalis, 3-8 parts of pueraria lobata, 2-6 parts of arisaema cum bile, 8-15 parts of antelope's horn, full worm
1-3 parts, 7-12 parts of Artemisia anomala；
Step is as follows：
（1）Keel and antelope's horn are broken into pieces and are together placed in container with tortoiseshell, it is crisp in forging on smokeless stove fire, ground after cooling
Into smalls, 90-110 mesh sieves are crossed；
（2）Wheat bran is crossed into 120-160 mesh sieves, in the hot pot that the wheat bran shone input is dryouied, is thrown when wheat bran is fried to 63-68 DEG C
Enter cape jasmine, Angelica sinensis, Moschus and stiff silkworm, stir-frying that will be repeatedly during frying and with slow boiling, frying 6-9 minutes, weeds out
Wheat bran, smalls is ground into by the cape jasmine fried, Angelica sinensis, Moschus and stiff silkworm；
（3）Chinese yam is cut into the block of coin-size, agaric is cleaned, filament is cut into and is mixed with Chinese yam block, be placed on food steamer and steam
The sweet wormwood silk cut is added after 25-35 minutes, is steamed again 8-13 minutes, is ground into the Chinese yam block steamed with rolling pin thick
Cream, by thick paste and micro-wave oven, toasts 2-5 minutes, dries in the air cool stand-by；
（4）Pueraria lobata, arisaema cum bile, full worm and Artemisia anomala are added water to cook twice, first time water consumption is pueraria lobata, arisaema cum bile, full worm
With 2.5-3.5 times of Artemisia anomala gross weight, big fire is decocted to boiling, treat boiling filter after five minutes, obtain filtrate 1, filter residue adds again
Water small fire is simmered 50-70 minutes slowly, is changed big fire and is decocted 3-8 minutes, and filtering, obtains filtrate 2, filtrate 1 and filtrate 2 are mixed, and stands 3-5
Hour, obtain supernatant；
（5）By step（4）Gained supernatant small fire decocts to boiling and adds step slowly（1）-（3）Gained medicine, with chopsticks while decocting
Deep sea fish oil and indigo naturalis are added after boiling while stirring to complete melt, 1.2 times of thick paste weight is added when abundant concentration is thick paste
Honey, cease fire after mixing, thick paste be placed on iron plate, small fire is dried 8-14 minutes slowly, obtains drying object, by drying object according to every bag
2-4 grams is prepared into electuary.
2. the preparation method of instant particles as Chinese medicine according to claim 1, it is characterised in that：Each raw material is as follows：8-13 parts of cape jasmine,
13-18 parts of Angelica sinensis, 5-7 parts of Moschus, 4-6 parts of tortoiseshell, 2-4 parts of keel, 4-7 parts of Chinese yam, 2-4 parts of stiff silkworm, 8-13 parts of sweet wormwood, agaric
6-8 parts, 3-5 parts of deep sea fish oil, 2-4 parts of indigo naturalis, 4-7 parts of pueraria lobata, 3-5 parts of arisaema cum bile, 10-13 parts of antelope's horn, full worm 1.5-2.5
Part, 9-11 parts of Artemisia anomala.
3. the preparation method of instant particles as Chinese medicine according to claim 1, it is characterised in that：Each raw material is as follows：10 parts of cape jasmine, when
Return 15 parts, 6 parts of Moschus, 5 parts of tortoiseshell, 3 parts of keel, 5.5 parts of Chinese yam, 3 parts of stiff silkworm, 10 parts of sweet wormwood, 7 parts of agaric, deep sea fish oil 4
Part, 3 parts of indigo naturalis, 5 parts of pueraria lobata, 4 parts of arisaema cum bile, 11 parts of antelope's horn, complete 2 parts of worm, 10 parts of Artemisia anomala.
4. the preparation method of instant particles as Chinese medicine according to claim 1, it is characterised in that：Step（1）It is ground into after cooling thin
End, crosses 100 mesh sieves.
5. the preparation method of instant particles as Chinese medicine according to claim 1, it is characterised in that：Step（2）Treat that wheat bran is fried to 65 DEG C
When put into cape jasmine, Angelica sinensis, Moschus and stiff silkworm.
6. the preparation method of instant particles as Chinese medicine according to claim 1, it is characterised in that：Step（2）Will during frying
Stir-frying repeatedly and with slow boiling, frying 8 minutes.
7. the preparation method of instant particles as Chinese medicine according to claim 1, it is characterised in that：Step（3）It is placed on food steamer and steams
The sweet wormwood silk cut is added after 25-35 minutes, is steamed again 10 minutes.
8. the preparation method of instant particles as Chinese medicine according to claim 1, it is characterised in that：Step（4）First time water consumption is
Pueraria lobata, arisaema cum bile, 3 times of full worm and Artemisia anomala gross weight.
9. the preparation method of instant particles as Chinese medicine according to claim 1, it is characterised in that：Step（4）By filtrate 1 and filtrate 2
Mix, when standing 4 is small.
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| CN1785409A (en) * | 2005-11-17 | 2006-06-14 | 西安千禾药业有限责任公司 | Medicine for treating epilepsy clonus, child convulsion, prosopospasm and its preparation method |
| CN102988772A (en) * | 2012-10-23 | 2013-03-27 | 潘根起 | TCM (Traditional Chinese medicine) composition for treating infantile acute infantile convulsions and preparation method thereof |
| CN103800705A (en) * | 2012-11-12 | 2014-05-21 | 张洪军 | Traditional Chinese medicine formula for treating convulsion in children |
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| CN1785409A (en) * | 2005-11-17 | 2006-06-14 | 西安千禾药业有限责任公司 | Medicine for treating epilepsy clonus, child convulsion, prosopospasm and its preparation method |
| CN102988772A (en) * | 2012-10-23 | 2013-03-27 | 潘根起 | TCM (Traditional Chinese medicine) composition for treating infantile acute infantile convulsions and preparation method thereof |
| CN103800705A (en) * | 2012-11-12 | 2014-05-21 | 张洪军 | Traditional Chinese medicine formula for treating convulsion in children |
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| 1275例小儿惊风中药处方分析;林远灿等;《海峡药学》;20111231;第23卷(第7期);第180-181页 * |
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