CN104547024A - Medicine for treating trachoma - Google Patents
Medicine for treating trachoma Download PDFInfo
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- CN104547024A CN104547024A CN201510024876.4A CN201510024876A CN104547024A CN 104547024 A CN104547024 A CN 104547024A CN 201510024876 A CN201510024876 A CN 201510024876A CN 104547024 A CN104547024 A CN 104547024A
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- trachoma
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/536—Prunella or Brunella (selfheal)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a medicine for treating trachoma. The medicine is prepared from the following raw medicinal materials in parts by weight: 15 parts of mongolian dandelion herb, 9 parts of cicada slough, 9 parts of fruit-spike of common selfheal and 12 parts of chrysanthemum flower. Clinical experiments prove that the medicine disclosed by the invention can be used for safely and effectively treating trachoma.
Description
Technical field
The present invention relates to a kind of medicine, be specifically related to a kind of Chinese medicine being used for the treatment of trachoma.
Background technology
Trachoma, trachoma is a kind of chronic infectious conjunctivokeratitis caused by chlamydia trachomatis, because it forms hackly outward appearance on palpebral conjunctiva surface, the likeness in form grains of sand, therefore named trachoma.The early stage conjunctiva of primary disease pathological process has infiltration, as nipple, follicle hypertrophy, corneal pannus occurs simultaneously; Late period the palpebral conjunctiva generation cicatrix owing to getting involved so that entropion deformity, increase the weight of the infringement of cornea, vision can be had a strong impact on and even cause blind.5 ~ 14 days incubation periods, eyes are ill, are multiplely born in child or juvenile period.
Clinical manifestation mostly is acute onset, and patient has foreign body sensation, and photophobia is shed tears, more mucus or mucus purulent secretion.After several weeks, acute symptom disappears, and enters chronic phase, now without any discomfort or can only feel eyes tire easily, as in now curing or spontaneous recovery, can not stay cicatrix.But in the chronic course of disease, often there is repeated infection in Prevalent district, aggravation.When cornea having activeness pannus, irritation becomes significantly, visual deterioration.Late period, as entropion, trichiasis, corneal ulcer and xerophthalmia etc., symptom was more obvious, and has a strong impact on vision, even blind often because of sequela.
Trachoma belongs to " trachoma " category of motherland's medical science.The evil poison of affection due to external wind and heat, inside have damp-heat in the spleen and stomach, qi-blood disharmony heat in blood harmony is stagnant is its basic pathogenesis.Primary disease is the card of the domination of pathogen.At the beginning of morbidity.Have puckery discomfort of slightly itching, in eyelid, the visible a small amount of red fine particle in nearly corner of the eyes portion, mostly is pathogenic wind-heat staying within eyelid; Then PD, mucopurulent secretion of the eyes like glue, husky puckery difficulty is opened, and is retention of heat in the spleen and stomach; The state of an illness further develops, and the heavy difficulty of patient's eyelid is opened, and profit pain is scorching hot, and in eyelid, pimple is uneven, then for heat in blood is stopped up stagnant.
Medical material involved in the present invention is all recorded in " Chinese Pharmacopoeia ".
Summary of the invention
The present invention aims to provide a kind of medicine being used for the treatment of trachoma, by selecting suitable medical material and proportioning thereof, reaches the safe and effective object being applied to trachoma treatment.
In order to achieve the above object, the present invention is by the following technical solutions:
Be used for the treatment of a medicine for trachoma, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Taraxaci 15 parts, Periostracum Cicadae 9 parts, Spica Prunellae 9 parts, Flos Chrysanthemi 12 parts.
Inventor, according to the Couple herbs had the deep influence of a scholarly family, understands the main idea that ancient books and records are discussed, and in conjunction with the pathological study of modern medicine to ophthalmic diseases, sums up the present invention, in order to treat trachoma.In side, Herba Taraxaci returns liver, stomach warp, and heat-clearing and toxic substances removing, for conjunctival congestion and swelling pain; Periostracum Cicadae returns lung, Liver Channel, dispelling wind and heat pathogens, relieving sore throat to recover voice, rash, improving acuity of vision and removing nebula, endogenous wind stopping relieving convulsion; Spica Prunellae, has the effect of improving eyesight of relieving inflammation or internal heat, and can control conjunctival congestion and swelling pain, headache; Flos Chrysanthemi, returns Liver Channel, clearing away heat to improve acuity of vision.All medicines share, and treatment trachoma, can accomplish that As the medicine took effect, the symptoms lessened substantially.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects 60 routine patients in December, 2012 altogether by during in JIUYUE, 2013, patient dependence is all good, can follow up a case by regular visits to check.In 60 routine patients, man 30 example, female 30 example, at minimum 4 years old of age, maximum 55 years old, the course of disease was the shortest 1 month, the longest nearly 1 year.Be divided into treatment group and each 30 examples of matched group at random, compare physical data there was no significant difference, there is comparability for two groups.
2, research method
2.1 Therapeutic Method
Treatment group takes the decoct that the present invention obtains according to specific embodiment 1, and every bu morning, noon and afternoon take for three times.
Matched group uses 1% rifampicin eye drop, uses according to its description.
All treat 2 months for two groups.
2.2 statistical method
Adopt SPSS16.0 statistics software data processing.
3, therapeutic outcome
3.1 criterion of therapeutical effect
Cure: without secretions, foreign body sensation and puckery burning sensation of itching disappear, and conjunctival congestion is disappeared, and folliculus or nipple disappear completely, and color and luster is normal; Effective: without secretions, foreign body sensation and puckery itching scorching hotly obviously alleviate, and conjunctival congestion is disappeared substantially, and folliculus or nipple disappear; Effective: secretions reduces, and foreign body sensation and puckery burning sensation of itching alleviate, and conjunctival congestion alleviates, and is formed without obvious folliculus; Invalid: symptom and sign are not improved or increased the weight of.
Total effective rate=(cure+effective+effectively) total number of cases × 100% of ÷.
3.2 liang of group curative effects
Result treatment group cures 10 examples, effective 16 examples, effective 3 examples, invalid 1 example, total effective rate 96.7%; Matched group cures 6 examples, effective 16 examples, effective 3 examples, and invalid 5 examples, total effective rate 83.3%, visible treatment group effective percentage is significantly better than matched group.
3.3 untoward reaction
Over the course for the treatment of, there is conjunctival congestion 3 example in matched group to patient, treatment group has no obvious adverse reaction.
Visible, the medicine that the present invention obtains can safe and effective treatment trachoma, has good medical science promotional value.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Herba Taraxaci 15 parts, Periostracum Cicadae 9 parts, Spica Prunellae 9 parts, Flos Chrysanthemi 12 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.
Be used for the treatment of trachoma.Oral, every bu morning, noon and afternoon take for three times.
Embodiment 2
Take: Herba Taraxaci 15 parts, Periostracum Cicadae 9 parts, Spica Prunellae 9 parts, Flos Chrysanthemi 12 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.
Be used for the treatment of trachoma.Oral, daily once.
Embodiment 3
Take: Herba Taraxaci 15 parts, Periostracum Cicadae 9 parts, Spica Prunellae 9 parts, Flos Chrysanthemi 12 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.
Be used for the treatment of trachoma.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. be used for the treatment of a medicine for trachoma, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Taraxaci 15 parts, Periostracum Cicadae 9 parts, Spica Prunellae 9 parts, Flos Chrysanthemi 12 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510024876.4A CN104547024A (en) | 2015-01-19 | 2015-01-19 | Medicine for treating trachoma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510024876.4A CN104547024A (en) | 2015-01-19 | 2015-01-19 | Medicine for treating trachoma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104547024A true CN104547024A (en) | 2015-04-29 |
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ID=53064796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510024876.4A Pending CN104547024A (en) | 2015-01-19 | 2015-01-19 | Medicine for treating trachoma |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998808A (en) * | 2016-06-27 | 2016-10-12 | 吕伟 | Traditional Chinese medicine composition for treating trachoma |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0597690A (en) * | 1991-04-10 | 1993-04-20 | Nissei Marine Kogyo Kk | Composition having action to maintain ophthalmic function and to remit ophthalmic disease |
| CN103655773A (en) * | 2013-12-09 | 2014-03-26 | 颉垚 | Traditional Chinese medicine formula for treating trachoma |
-
2015
- 2015-01-19 CN CN201510024876.4A patent/CN104547024A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0597690A (en) * | 1991-04-10 | 1993-04-20 | Nissei Marine Kogyo Kk | Composition having action to maintain ophthalmic function and to remit ophthalmic disease |
| CN103655773A (en) * | 2013-12-09 | 2014-03-26 | 颉垚 | Traditional Chinese medicine formula for treating trachoma |
Non-Patent Citations (1)
| Title |
|---|
| 黄湘铭等: "消炎明目汤治疗睑缘炎", 《山东中医杂志》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105998808A (en) * | 2016-06-27 | 2016-10-12 | 吕伟 | Traditional Chinese medicine composition for treating trachoma |
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Application publication date: 20150429 |