CN105998808A - Traditional Chinese medicine composition for treating trachoma - Google Patents

Traditional Chinese medicine composition for treating trachoma Download PDF

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CN105998808A
CN105998808A CN201610482609.6A CN201610482609A CN105998808A CN 105998808 A CN105998808 A CN 105998808A CN 201610482609 A CN201610482609 A CN 201610482609A CN 105998808 A CN105998808 A CN 105998808A
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chinese medicine
trachoma
herba
medicine composition
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吕伟
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11—Pteridophyta or Filicophyta (ferns)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/57—Magnoliaceae (Magnolia family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/716—Clematis (leather flower)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/744—Gardenia
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/888—Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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Abstract

The invention discloses a traditional Chinese medicine composition for treating trachoma and belongs to the technical field of traditional Chinese medicine. The defects that existing drugs are poor in treatment effect and low in cure rate when used for treating trachoma are overcome. The traditional Chinese medicine composition is prepared from, by weight, 1-5 parts of herbal pyrolae, 4-8 parts of rhizoma phragmitis, 3-8 parts of herbal lophatheri, 1-3 parts of radix clematidis, 0.5-1.5 parts of caulis sinomenii, 5-10 parts of herbal taraxaci, 8-13 parts of cortex fraxini, 7-14 parts of fructus schisandrae chinensis, 5-10 parts of herbal equiseti hiemalis, 3-8 parts of fructus gardeniae, 1-5 parts of herbal lycopodii, 1-3 parts of rhizoma homalomenae and 1-3 parts of periostracum cicada. The traditional Chinese medicine composition is suitable for patients suffering from trachoma, the cure rate is 96%, the total effective rate is 100%, and the problem of trachoma relapse is solved.

Description

The Chinese medicine composition for the treatment of trachoma
Technical field
The present invention relates to a kind of Chinese medicine composition treating trachoma, belong to technical field of Chinese medicines.
Background technology
Trachoma is a kind of chronic infectious conjunctivokeratitis caused by chlamydia trachomatis.Because of its formed on palpebral conjunctiva surface coarse not Flat outward appearance, is similar to the grains of sand, therefore named trachoma.Trachoma is a kind of more obstinate disease, and administration time is longer, and the lighter or nothing are anti- Answering the infected, the several months can heal, and conjunctiva leaves over thin scar or without clear scar；Repeated infection person, the course of disease can the touching several years to many decades As long as, have a strong impact on vision and even cause blind.
Chlamydia trachomatis is insensitive to most antibiotics, there is no specific drug at present in treatment.Commonly use sulfonamides, Li Fu clinically The antibiotic suppression inflammatory reactions such as flat, erythromycin.Traditional Chinese medical science trachoma is called " trachoma ", it is believed that unclean, by wind heat because of eye more than it The evil invasion and attack of poison, taste have damp and hot in addition, cause eyelid venation harmony stagnant, qi-blood disharmony and send out.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating trachoma, determined curative effect, rapid-action, short treating period, cure Rate is high, non-relapse after healing.
The Chinese medicine composition of described treatment trachoma, is made up of the raw material of Chinese medicine of following weight portion: Herba Pyrolae 1-5 part, Rhizoma Phragmitis 4-8 Part, Folium Bambusae 3-8 part, Radix Clematidis 1-3 part, Caulis Sinomenii 0.5-1.5 part, Herba Taraxaci 5-10 part, Cortex Fraxini 8-13 part, Fructus Schisandrae Chinensis 7-14 part, Herba Equiseti Hiemalis's 5-10 part, Fructus Gardeniae 3-8 part, Herba Lycopodii 1-5 part, Rhizoma Homalomenae 1-3 part, Periostracum Cicadae 1-3 part.
The Chinese medicine composition of described treatment trachoma, it is characterised in that be made up of the raw material of Chinese medicine of following weight portion: Herba Pyrolae 3 Part, Rhizoma Phragmitis 6 parts, 5 parts of Folium Bambusae, Radix Clematidis 2 parts, Caulis Sinomenii 1 part, Herba Taraxaci 8 parts, Cortex Fraxini 10 parts, Fructus Schisandrae Chinensis 10 Part, Herba Equiseti Hiemalis 8 parts, Fructus Gardeniae 5 parts, Herba Lycopodii 3 parts, Rhizoma Homalomenae 2 parts, Periostracum Cicadae 2 parts.
Single dose dose: Herba Pyrolae 1-5g, Rhizoma Phragmitis 4-8g, Folium Bambusae 3-8g, Radix Clematidis 1-3g, Caulis Sinomenii 0.5-1.5g, Herba Taraxaci 5-10g, Cortex Fraxini 8-13g, Fructus Schisandrae Chinensis 7-14g, Herba Equiseti Hiemalis 5-10g, Fructus Gardeniae 3-8g, Herba Lycopodii 1-5g, Rhizoma Homalomenae 1-3g, Periostracum Cicadae 1-3g。
Preparation and instructions of taking: be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later.
The pharmacological action of each Chinese medicine:
Herba Pyrolae: sweet, bitter, temperature.Return liver, kidney channel.Function with cure mainly: wind-damp dispelling, bone and muscle strengthening, hemostasis, cough-relieving.For Rheumatic arthralgia, lumbago due to renal deficiency, weakness of the waist and knees, menorrhagia, chronic cough due to asthenia of viscera.
Rhizoma Phragmitis: sweet, cold.Attach to the lung and stomach meridians.Function with cure mainly: clearing away heat-fire, promoting the production of body fluid to quench thirst, relieving restlessness, preventing or arresting vomiting, diuresis. For calentura excessive thirst, cough due to lung-heat, lung abscess vomiting pus, gastric heat vomits the sound of vomiting, the puckery pain of pyretic stranguria.
Folium Bambusae: sweet light, cold.Enter the heart, lung, gallbladder, stomach warp.Function cures mainly: clearing heat and relieving fidgetness, diuresis of promoting the production of body fluid.Control calentura excessive thirst, Pediatric epilepsy scared, cough with dyspnea tells nosebleed, flushed complexion, oliguria also, erosion of the oral mucosa tongue boil.
Radix Clematidis: pungent, salty, temperature.Return bladder warp.Function with cure mainly: wind-damp dispelling, the meridian dredging.For rheumatic arthralgia, limbs Numbness, muscle arteries and veins contracture, joint stuffiness.
Caulis Sinomenii: bitter, pungent is flat.Return liver, spleen channel.Function with cure mainly: wind-damp dispelling, the meridian dredging, diuresis.For rheumatism Arthralgia pain, arthroncus, benumb pruritus.
Herba Taraxaci: cold in nature, bitter in the mouth, sweet.Function cures mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For acute mastitis, scrofula The puckery pain of scrofula, furuncle swelling toxin, pharyngalgia, lung abscess, acute appendicitis, conjunctival congestion, jaundice due to damp-heat, pyretic stranguria.
Cortex Fraxini: bitter, puckery, cold.Return liver, gallbladder, large intestine channel.Function with cure mainly: heat clearing and damp drying, astringent therapy dysentery relieving, leukorrhagia stopping, bright Mesh.For damp-heat dysentery, leucorrhea with red and white discharge, conjunctival congestion and swelling pain, the raw nebula film of mesh.
Fructus Schisandrae Chinensis: sour, sweet, temperature.Return lung, the heart, kidney channel.Function with cure mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming. For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, and cardiopalmus is lost Sleep.
Herba Equiseti Hiemalis: sweet, bitter, flat.Return lung, Liver Channel.Function with cure mainly: dispelling wind and heat pathogens, improving acuity of vision and removing nebula.For wind heat conjunctival congestion, Epiphora induced by wind, the raw nebula of mesh.
Fructus Gardeniae: cold in nature, bitter in the mouth.Function cures mainly: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body., jaundice vexed for calentura Dark coloured urine, blood strangury and dry pain, heat in blood tell nosebleed, mesh outstanding person swells and ache, pathogenic fire,toxin and furuncles, sprain.
Herba Lycopodii: micro-hardship, pungent, temperature.Return liver,spleen,kidney warp.Function with cure mainly: expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.For closing Joint is ached, joint stuffiness.
Rhizoma Homalomenae: bitter, pungent, temperature.Return liver, kidney channel.Function with cure mainly: wind-damp dispelling, strengthening bone and muscle.For anemofrigid-damp arthralgia, waist Knee joint cold type of pain, contracture is numb, and muscles and bones flaccidity is soft.
Periostracum Cicadae: sweet, cold.Return lung, Liver Channel.Function with cure mainly: dispelling wind and heat pathogens, sore-throat relieving, rash, improving acuity of vision and removing nebula, spasmolytic. For anemopyretic cold, pharyngalgia hoarseness, measles without adequate eruption, rubella pruritus, cataract, convulsion with spasms, tetanus.
Compared with prior art, the invention has the beneficial effects as follows:
The present invention is based on Traditional Chinese medical theory, and with natural Chinese medicinal herb as raw material, scientific compatibility, medication is gentle, and all medicines share There is expelling wind and removing dampness, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, effects such as improving eyesight of promoting the production of body fluid, can effectively cure various acute and chronic trachoma, this Bright through example clinical practices up to ten thousand verify, it is evident in efficacy, mild in medicine property and, reliable effect, have no side effect, cure rate 96%, Total effective rate 100%, solves a difficult problem for trachoma recurrent exerbation.
Below in conjunction with clinical trial and model case, the present invention will be further described.
One, clinical trial:
1, clinical data:
Randomly selecting various acute and chronic patients with trachomas 100, the age is between 10-56 year.Trachoma diagnosis basis is: 1. go up vault Grand portion and the fuzzy hyperemia of upper tarsal conjunctiva blood vessel, nipple hypertrophy or folliculus are formed, or the two has concurrently.2. with magnifier or slit lamp Check visible corneal pannus.3. fornices is gone up or/and cicatrix occurs in upper tarsal conjunctiva.4. conjunctiva scraping blade has lindner's initial body.? On the basis of 1, have one of other 3 the diagnosable trachomas of person concurrently.
2, Therapeutic Method:
Taking Chinese medicine composition of the present invention to be decocted in water for oral dose, every day, potion, divided twice one after each meal sooner or later.3 days 1 courses for the treatment of, general medication 3-5 can fully recover the course for the treatment of.
3, criterion of therapeutical effect:
Recovery from illness: itch, pain, the ophthalmic uncomfortable transference cure such as shed tears；
Effective: itch, pain, the ophthalmic uncomfortable symptom such as shed tears are obviously improved；
Invalid: itch, pain, the ophthalmic uncomfortable symptom such as shed tears be without taking a turn for the better.
4, therapeutic outcome:
After 100 patients with trachoma medication 3-5 courses for the treatment of, 96 people's recoveries from illness, 4 people take a turn for the better, cure rate 96%, effective percentage 100%.
Model case
Lin, female, 32 years old, suffer from trachoma more than 3 years, sensation eye has foreign body sensation at ordinary times, and eye is puckery itches, and sees distinguished and admirable tear, through inspection Looking into its eyelid of discovery, rubescent in mild hyperaemia state, palpebral conjunctiva face is rough, and nipple hypertrophy also has folliculus to be formed, upper tarsal conjunctiva Cicatrix occurs.Once multiple method was used to treat, poor effect, recurrent exerbation, take the present invention and treat the Chinese medicine composition of trachoma After 3 days, ophthalmic uncomfortable sense is obviously improved, 4 courses for the treatment of of medication, recovery from illness, follows up a case by regular visits to 1 year without recurrence.
Liu, man, 16 years old, ophthalmic pruritus, there is foreign body sensation three wheat harvesting period, and when night reads a book, eye is puckery, pain, secretions is more, Think it is excess eye-using, use anti-asthenopic eye drop a few days, still not onset, upon examination it is found that its red of eyelid inner face visible red Grain, venation is smudgy, with corneal pannus seen from slit lamp examination, is diagnosed as trachoma, takes the present invention and treats in trachoma After one course for the treatment of of drug composition, ophthalmic uncomfortable sense is obviously improved, 3 courses for the treatment of of medication, itch, the eye such as pain, foreign body sensation not Suitable transference cure, follows up a case by regular visits to 1 year without recurrence.
Specific implementation method
Below in conjunction with detailed description of the invention, the invention will be further described.
Embodiment 1
The Chinese medicine composition of described treatment trachoma, is made up of the raw material of Chinese medicine of following weight portion: Herba Pyrolae 1 part, Rhizoma Phragmitis 4 parts, 3 parts of Folium Bambusae, Radix Clematidis 1 part, Caulis Sinomenii 0.5 part, Herba Taraxaci 5 parts, Cortex Fraxini 8 parts, Fructus Schisandrae Chinensis 7-14 part, Herba Equiseti Hiemalis 5-10 Part, Fructus Gardeniae 3-8 part, Herba Lycopodii 1-5 part, Rhizoma Homalomenae 1-3 part, Periostracum Cicadae 1-3 part.
Embodiment 2
The Chinese medicine composition of described treatment trachoma, it is characterised in that be made up of the raw material of Chinese medicine of following weight portion: Herba Pyrolae 3 Part, Rhizoma Phragmitis 6 parts, 5 parts of Folium Bambusae, Radix Clematidis 2 parts, Caulis Sinomenii 1 part, Herba Taraxaci 8 parts, Cortex Fraxini 10 parts, Fructus Schisandrae Chinensis 10 Part, Herba Equiseti Hiemalis 8 parts, Fructus Gardeniae 5 parts, Herba Lycopodii 3 parts, Rhizoma Homalomenae 2 parts, Periostracum Cicadae 2 parts.
Embodiment 3
The Chinese medicine composition of described treatment trachoma, is made up of the raw material of Chinese medicine of following weight portion: Herba Pyrolae 1-5 part, Rhizoma Phragmitis 4-8 Part, Folium Bambusae 3-8 part, Radix Clematidis 1-3 part, Caulis Sinomenii 0.5-1.5 part, Herba Taraxaci 5-10 part, Cortex Fraxini 8-13 part, Fructus Schisandrae Chinensis 7-14 part, Herba Equiseti Hiemalis's 5-10 part, Fructus Gardeniae 3-8 part, Herba Lycopodii 1-5 part, Rhizoma Homalomenae 1-3 part, Periostracum Cicadae 1-3 part.

Claims (2)

1. the Chinese medicine composition treating trachoma, it is characterised in that be made up of the raw material of Chinese medicine of following weight portion: Herba Pyrolae 1-5 part, Rhizoma Phragmitis 4-8 part, Folium Bambusae 3-8 part, Radix Clematidis 1-3 part, Caulis Sinomenii 0.5-1.5 part, Herba Taraxaci 5-10 part, Cortex Fraxini 8-13 part, Fructus Schisandrae Chinensis 7-14 part, Herba Equiseti Hiemalis's 5-10 part, Fructus Gardeniae 3-8 part, Herba Lycopodii 1-5 part, Rhizoma Homalomenae 1-3 part, Periostracum Cicadae 1-3 Part.
The Chinese medicine composition for the treatment of trachoma the most according to claim 1, it is characterised in that the Chinese medicine by following weight portion is former Material composition: Herba Pyrolae 3 parts, Rhizoma Phragmitis 6 parts, 5 parts of Folium Bambusae, Radix Clematidis 2 parts, Caulis Sinomenii 1 part, Herba Taraxaci 8 parts, Cortex Fraxini 10 parts, Fructus Schisandrae Chinensis 10 parts, Herba Equiseti Hiemalis 8 parts, Fructus Gardeniae 5 parts, Herba Lycopodii 3 parts, Rhizoma Homalomenae 2 parts, Periostracum Cicadae 2 parts.
CN201610482609.6A 2016-06-27 2016-06-27 Traditional Chinese medicine composition for treating trachoma Pending CN105998808A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1895426A (en) * 2006-06-28 2007-01-17 王军 Vision-improving electuary
CN101244126A (en) * 2007-02-13 2008-08-20 汪建国 Composition for treating eye disease and preparation method
CN104547024A (en) * 2015-01-19 2015-04-29 耿建芳 Medicine for treating trachoma

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1895426A (en) * 2006-06-28 2007-01-17 王军 Vision-improving electuary
CN101244126A (en) * 2007-02-13 2008-08-20 汪建国 Composition for treating eye disease and preparation method
CN104547024A (en) * 2015-01-19 2015-04-29 耿建芳 Medicine for treating trachoma

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Application publication date: 20161012