CN1045388C - Four-herb protein reducing soup for treatment of proteinuria caused by acute and chronic nephritis and producing method thereof - Google Patents
Four-herb protein reducing soup for treatment of proteinuria caused by acute and chronic nephritis and producing method thereof Download PDFInfo
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Abstract
The present invention relates to a four-herb protein reducing soup for treating proteinuria caused by nephritis, which is composed of 16 Chinese herbs of herb potentillae chinensis, spreading hedvotis herb, longhairy antenoron herb, ecliptae herb, common threewingnut root, cornel, radix achyranthis bidentatae, glossy privet fruit, milkvetch root, poria from yunnan of china, water plantain, baical skullcap root, cortex moutan root-bark of tree peony, keel and oyster shell, and the 16 Chinese herbs are matched according to different weight, and the total weight of each potion is 248g, the Chinese herbs of each potion are ground and infused and are decocted with water for two times, and the physic liquor is filtered out and is concentrated to 150 to 250 ml; the effective rate for treating proteinuria caused by acute nephritis and chronic nephritis reaches 98%, and the present invention has the advantages of no toxic or side effect, no relapse phenomenon, abundant medicine sources and low cost, can be in mass production of industrialization, and can also be prepared in families.
Description
The present invention relates to four-herb protein reducing soup medicament of controlling acute and chronic nephritic proteinuria and preparation method thereof.
At present, the medicine of controlling acute and chronic nephritic proteinuria mainly is the pill with the preparation of Chinese herbal medicine such as Cordyceps, the Radix Astragali, Folium Pyrrosiae, Semen Plantaginis, Poria, goldenseal, Herba Orostachyos, Radix Tripterygii Wilfordii, Herba Begoniae Yunnanensis, medicine such as tablet and decoction (slow renal aid, SHENYAN SIWEI PIAN, kidney tonifying liquid etc.), it is synthetic etc. that preparation method has decocting and chemistry to refine, the medicament preparation method more complicated that has.These pills, tablet and decoction have certain effect to controlling acute and chronic nephritic proteinuria, and effective percentage is below 40%, and relapse rate is generally more than 80%, and long-term effect less than 15% has side effect behind the clothes that have.
The objective of the invention is to adopt 16 flavor natural Chinese medicinal herb preparations such as Herba Potentillae Chinensis, Herba Hedyotidis Diffusae, Herba Lysimachiae, Herba Ecliptae to control the four-herb protein reducing soup of acute and chronic nephritic proteinuria, but heat-clearing and toxic substances removing, reinforcing kidney and strengthening resistance is removed albumen, strengthens body immunity, have no side effect, improve effective percentage greatly, reduce relapse rate, long-term effect is very remarkable, and can carry out the industrial mass manufacturing and produce, can prepare by family oneself again.The present invention is achieved in that
One, the constituent of medicament and deal thereof
Selecting for use following 16 flavor Chinese herbal medicine to be configured to gross weight is 248 grams, and the title of 16 flavor Chinese herbal medicine and weight composition are: Herba Potentillae Chinensis 10-50 gram, Herba Hedyotidis Diffusae 10-40 gram, Herba Lysimachiae 10-30 grams, Herba Ecliptae 15 grams, Radix Tripterygii Wilfordii 3-5 gram, Fructus Corni 15 grams, Radix Achyranthis Bidentatae 12 grams, Fructus Ligustri Lucidi 15 grams, the Radix Astragali 15 grams, Poria 12 grams, Rhizoma Alismatis 12 grams, Radix Scutellariae 10-30 gram, Cortex Moutan 12 grams, Os Draconis 15 grams, Concha Ostreae 15 grams, Radix Glycyrrhizae 6 grams.
Two, medicament preparation method:
1. get Cortex Moutan, Poria, Rhizoma Alismatis, Os Draconis, Concha Ostreae, Radix Tripterygii Wilfordii 6 flavor Chinese herbal medicine and roll into coarser powder respectively No. 3.
2. get Herba Potentillae Chinensis, Herba Hedyotidis Diffusae, Herba Lysimachiae, Herba Ecliptae, Fructus Corni, Radix Achyranthis Bidentatae, Fructus Ligustri Lucidi, the Radix Astragali, Radix Scutellariae, Radix Glycyrrhizae and place together, soaked 1-2 hour with clear water.
3. medicine after will soaking and medicinal liquid mix with the 6 flavor medicines that roll into coarser powder, successively decoct with water twice.Add water 4-6 before decocting for the first time and doubly measure, boiled taking liquid, filtration 1-1.5 hour.Add 2-4 times of water gaging and carry out decocting the second time, boiled 0.5-1 hour, taking liquid filters again.Two parts of medicinal liquids are merged, are concentrated into the 150-250 milliliter with boiling, four remove from office and fall the plain soup agent, equal portions are adorned two bottles.
4. for long preservation, the plain soup agent is fallen in four leather of making pack in the dark-coloured vial, the sealing bottleneck places ventilations, shady and cool dry locating to get final product.
5. industrialized mass, also can carry out with step as stated above, as long as increase the multiple that the Chinese herbal medicine proportioning of getting becomes 248 gram Chinese herbal medicine and decocts amount of water, just can prepare the umber that obtains with the four-herb protein reducing soup agent that increases the identical multiple number of the dose and the water yield, every part is 150 milliliters to 250 milliliters four-herb protein reducing soup agent.
The present invention is when selecting for use 16 flavor Chinese herbal medicine to be configured to 248 gram gross weights, and Herba Potentillae Chinensis 10 to 50 grams of selecting for use are from Serpentis SHECAO 10 to 40 grams, Herba Lysimachiae 10 to 30 grams, Radix Tripterygii Wilfordii 3 to 5 grams, Radix Scutellariae 10 to 30 grams, the weight proportion of this Chinese medicine of the five flavours all is effective in demonstrate circle.
Facts have proved that it is fine to treat acute and chronic nephritic proteinuria effect, has reached heat-clearing and toxic substances removing, reinforcing kidney and strengthening resistance is removed Xu Bai, enhancing human body immunity power, the purpose of nontoxic again, side effect; And preparation method is simple.Not only can carry out industrialized mass, also can prepare by family.
From 265 routine nephritic proteinuria patients are taken observation, produce effects person reaches 245 examples, accounts for 92%; Responder's 16 examples account for 6%; Nonresponder's 4 examples account for 2%.Total effective rate reaches 98%.Up to the present, do not find toxic and side effects phenomenon and disease relapse phenomenon.
Embodiments of the invention have:
1. get Cortex Moutan 12 grams, Poria 12 grams, Rhizoma Alismatis 12 grams, Os Draconis 15 grams, Concha Ostreae 15 grams, Radix Tripterygii Wilfordii 3 grams roll into coarser powder respectively No. 3.Get Herba Potentillae Chinensis 50 grams, Herba Hedyotidis Diffusae 11 grams, Herba Lysimachiae 10 grams, Herba Ecliptae 15 grams, Fructus Corni 15 grams, Radix Achyranthis Bidentatae 12 grams, Fructus Ligustri Lucidi 15 grams, the Radix Astragali 15 grams, Radix Scutellariae 30 grams, Radix Glycyrrhizae 6 grams are placed together and were soaked one hour with clear water, and above-mentioned 6 flavor Chinese herbal medicine are mixed together with soak, successively decoct twice.Add water 992 grams before decocting for the first time, boiled one hour, taking liquid, filtration.Add water 496 grams again and carry out decocting the second time, boiled 30 minutes, more taking liquid, filtration.Two parts of medicinal liquids are merged, be concentrated into 150 milliliters, promptly become the four-herb protein reducing soup of controlling acute and chronic nephritic proteinuria with boiling method.
2. get Cortex Moutan 12 grams, Poria 12 grams, Rhizoma Alismatis 12 grams, Os Draconis 15 grams, Concha Ostreae 15 grams, it is No. 3 coarser powder that Radix Tripterygii Wilfordii 5 grams roll respectively.Get Herba Potentillae Chinensis 10 grams, Herba Hedyotidis Diffusae 40 restrains, Herba Lysimachiae 30 grams, and Herba Ecliptae 15 grams, Fructus Corni 15 grams, Radix Achyranthis Bidentatae 12 grams, Fructus Ligustri Lucidi 15 restrains, the Radix Astragali 15 grams, Radix Scutellariae 19 grams, Radix Glycyrrhizae 6 grams are placed one and are reinstated clear water immersion two hours.Above-mentioned 16 flavor Chinese herbal medicine are mixed together with soak, successively decoct secondary.Add water 1488 grams before decocting for the first time, boiled one and a half hours, taking liquid filters.Add water 992 grams again, carry out decocting the second time, boiled 60 minutes, taking liquid filters.Merge two parts of medicinal liquids then, be concentrated into 250 milliliters, promptly become the four-herb protein reducing soup agent of controlling acute and chronic nephritic proteinuria with boiling method.
3. get Cortex Moutan 12 grams, Poria 12 grams, Rhizoma Alismatis 12 grams, Os Draconis 15 grams, Concha Ostreae 15 grams, it is No. 3 coarser powder that Radix Tripterygii Wilfordii 4 grams roll respectively.Get Herba Potentillae Chinensis 35 grams, Herba Hedyotidis Diffusae 30 restrains, Herba Lysimachiae 25 grams, and Herba Ecliptae 15 grams, Fructus Corni 15 grams, Radix Achyranthis Bidentatae 12 grams, Fructus Ligustri Lucidi 15 restrains, the Radix Astragali 15 grams, Radix Scutellariae 10 grams, Radix Glycyrrhizae 6 grams are placed one and are reinstated clear water immersion one and a half hours.Above-mentioned 16 flavor Chinese herbal medicine are mixed together with soak, successively decoct secondary.Add water 1240 grams before decocting for the first time, boiled 75 minutes, taking liquid filters, add water 744 grams again, carry out decocting the second time, boiled 45 minutes, fall taking liquid again, filter, then two parts of medicinal liquids are merged, be concentrated into 200 milliliters, promptly become the four-herb protein reducing soup agent of controlling acute and chronic nephritic proteinuria with boiling method.
4. get Cortex Moutan 1200 grams, Poria 1200 grams, Rhizoma Alismatis 1200 grams, Os Draconis 1500 grams, Concha Ostreae 1500 grams, it is No. 3 coarser powder that Radix Tripterygii Wilfordii 300 grams roll respectively.Get Herba Potentillae Chinensis 5000 grams, Herba Hedyotidis Diffusae 1100 restrains, Herba Lysimachiae 1000 grams, and Herba Ecliptae 1500 grams, Fructus Corni 1500 grams, Radix Achyranthis Bidentatae 1200 grams, Fructus Ligustri Lucidi 1500 restrains, the Radix Astragali 1500 grams, Radix Scutellariae 3000 grams, Radix Glycyrrhizae 600 grams are placed one and are reinstated clear water immersion 1 hour.Above-mentioned 16 flavor Chinese herbal medicine are mixed together with soak, successively decoct secondary.Add 99.2 kilograms in water before decocting for the first time, boiled one hour, taking liquid filters.Add 49.6 kilograms in water again, boiled 30 minutes, fall taking liquid again, filter,, be concentrated into 10000 milliliters, 10000 milliliters of concentrated solutions are divided into 100 parts, promptly become the four-herb protein reducing soup agent of controlling acute and chronic nephritic proteinuria with conventional liquid concentration method two parts of medicinal liquids merging.Model case
Example one: high man of virtue and ability's English man, 38 years old, people from Zhao County, Hebei, the supply and marketing cadre suffered from chronic nephritis 6 years, and through economizing the various big hospital treatment, poor effect comes me institute to seek medical advice on February 25th, 1993, at that time the main suit; Malaise, soreness of waist lower limb is light.Check: the puffiness of the eyes, the complexion rolling is white; Red tongue, Tai Bailve is greasy; Rapid and stringy pulse, blood pressure: 160/100mmHg, cardiopulmonary (), routine urinalysis: urine protein (++), urine β 2-MG:2.5ng/ml; Blood potassium: 3.5mg% is through taking " four-herb protein reducing soup " 8 days, urine β 2-mg:2.5ng/ml (reducing to normal), urine protein (), blood potassium: 5.6mg% (reduce to normal) took medicine one month continuously, weakly obviously alleviated, appearance, edema of lower limbs disappears, routine urinalysis: urine protein ().
Example two: the fragrant woman of Zhang Ping, 45 years old, the cadre of province Bank of Communications, patient's lumbago soreness of waist, lower limb are weak, facial edema 14 years, go to a doctor to province, city's large hospital, be diagnosed as neurosis, the climacteric syndrome or the cause of disease are unclear, and on March 12nd, 1993 came me institute to seek medical advice, check: eyelid, facial edema, pale tongue are fat, indentation is arranged, and tongue is white, deep-thready pulse.Cardiopulmonary (one).Chemical examination: blood β 2-MG:6.4ng/ml; Urine protein (++).Took " four grass fall from soup " 7 days, eyelid, facial edema obviously alleviate, blood β 2-MG:5.4ng/ml, urine β 2-MG1.28ng/ml, urine protein () was taken medicine one month continuously, patient's symptom obviously alleviates, blood, urine β 2-MG all reduce to normally, urinate eight: albumen (one) remainder (), and among the existing still follow-up study.
Example three: Chen Lian lake man, 47 years old, people from Anhui, the self-employed entrepreneurs suffered from acute urinary system infection two days, the main suit: lumbago, dysurea, frequent micturition, urgent micturition.Check: red tongue, few tongue, deep pulse is number slightly, blood pressure: 90/60mmHg, routine urinalysis: BCD+++, RBC++, PRO ±, urine β 2-MG:0.12ng/ml; Blood β 2-MG:3.2ng/ml, urinaryalbumin: 22 μ g/ branches, took " four-herb protein reducing soup " 6 days, dysurea takes a turn for the better, urine BCD+, take medicine 20 days BCD (), PRO (), WBC (), the after treatment first quarter moon, transference cure is urinated eight (one).
Example four: Wang Yuzhou, the man, 53 years old, suffered from acute nephritis 10 days, to economize * * hospital seeks medical advice, and desires to give hormone " meticorten " and treats, the patient is reluctant to take hormone, comes me to seek medical advice on March 16th, 93, the main suit: the soreness of waist is weak, the puffiness of the eyes.Have a medical check-up: the puffiness of the eyes, the matter light red tongue, tongue is foretold yellow, and deep pulse is number slightly.Cardiopulmonary (one), chemical examination: urine protein +++, granular cast, urine β 2-MG:0.37 μ g/ue, blood β 2-MG:1.2 μ g/ue took " four-herb protein reducing soup " six days, urine protein ++, granular cast (), the first quarter moon of taking medicine, urine protein+, granular cast (), after treatment one month, urine protein (one), granular cast (), transference cure, in high spirits, antisecosis.
Claims (2)
1. a four-herb protein reducing soup of controlling nephritic proteinuria is characterized in that the gram by Herba Potentillae Chinensis 10-50, Herba Hedyotidis Diffusae 10-40 gram, Herba Lysimachiae 1O-30 gram, Herba Ecliptae 15 grams, Radix Tripterygii Wilfordii 3-5 gram, Fructus Corni 15 grams, Radix Achyranthis Bidentatae 12 grams, Fructus Ligustri Lucidi 15 grams, the Radix Astragali 15 grams, Poria 12 grams, Rhizoma Alismatis 12 grams, Radix Scutellariae 10-30 gram, Cortex Moutan 12 grams, Os Draconis 15 grams, Concha Ostreae 15 grams, Radix Glycyrrhizae 6 grams ten Six-element Chinese herbal medicine are made, and the gross weight of potion is 248 grams, soaks with clear water, successively decoct twice, filter, merge, be concentrated into the 150-250 milliliter respectively and form.
2. preparation method of controlling the four-herb protein reducing soup of nephritic proteinuria as claimed in claim 1 is characterized in that:
(1) gets Cortex Moutan, Poria, Rhizoma Alismatis, Os Draconis, Concha Ostreae, Radix Tripterygii Wilfordii and do not roll into coarser powder No. 3;
(2) getting Herba Potentillae Chinensis, Herba Hedyotidis Diffusae, Herba Lysimachiae, Herba Ecliptae, Fructus Corni, Radix Achyranthis Bidentatae, Fructus Ligustri Lucidi, the Radix Astragali, Radix Scutellariae, Radix Glycyrrhizae places one and reinstates clear water and soaked 1-2 hour;
(3) add water 4-6 after (1), (2) two parts 16 flavor Chinese herbal medicine are mixed together with soak and doubly measure, carry out decocting first time, boiled 1-1.5 hour, taking liquid, filtration; Add 2-4 again and doubly measure, carry out decocting the second time, boiled 0.5-1 hour, fall taking liquid again, filter, two parts of medicinal liquids are merged, be concentrated into the 150-250 milliliter with herbal decoction routine concentration method, control the four-herb protein reducing soup of nephritic proteinuria;
(4) be configured to every dose 248 gram during gross weight at selected this 16 flavor Chinese herbal medicine, Herba Potentillae Chinensis, the weight proportion of Herba Hedyotidis Diffusae, Herba Lysimachiae, Radix Tripterygii Wilfordii, this five tastes Chinese herbal medicine of Radix Scutellariae shown in all be effective in the scope;
(5) during industrialized great production, 248 gram gross weights of forming with this 16 flavor Chinese herbal medicine weight proportion and decoct amount of water by identical multiple increase can obtain the medicament of the umber identical with increasing multiple.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN93108852A CN1045388C (en) | 1993-07-22 | 1993-07-22 | Four-herb protein reducing soup for treatment of proteinuria caused by acute and chronic nephritis and producing method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN93108852A CN1045388C (en) | 1993-07-22 | 1993-07-22 | Four-herb protein reducing soup for treatment of proteinuria caused by acute and chronic nephritis and producing method thereof |
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| CN1085096A CN1085096A (en) | 1994-04-13 |
| CN1045388C true CN1045388C (en) | 1999-10-06 |
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| CN93108852A Expired - Fee Related CN1045388C (en) | 1993-07-22 | 1993-07-22 | Four-herb protein reducing soup for treatment of proteinuria caused by acute and chronic nephritis and producing method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1054981C (en) * | 1994-12-14 | 2000-08-02 | 天津同仁堂制药厂 | Tablet for nephritis |
| CN1053368C (en) * | 1995-12-07 | 2000-06-14 | 缑建华 | Pill for treatment nephritis |
| CN105411692B (en) * | 2015-12-15 | 2019-02-19 | 广州医科大学附属口腔医院 | A kind of III type personalized function appliance |
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1993
- 1993-07-22 CN CN93108852A patent/CN1045388C/en not_active Expired - Fee Related
Non-Patent Citations (1)
| Title |
|---|
| 《北京中医》1990（2） 1990. 1. 1 谢森，"加味渗芪地黄汤治疗蛋白尿58例临床观察" * |
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| CN1085096A (en) | 1994-04-13 |
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