CN104524483A - Tincture for promoting bone injury healing and preparation method thereof - Google Patents

Tincture for promoting bone injury healing and preparation method thereof Download PDF

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CN104524483A
CN104524483A CN201510051657.5A CN201510051657A CN104524483A CN 104524483 A CN104524483 A CN 104524483A CN 201510051657 A CN201510051657 A CN 201510051657A CN 104524483 A CN104524483 A CN 104524483A
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parts
radix
rhizoma
tincture
herba
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冯波
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Abstract

The invention discloses a tincture for promoting bone injury healing. The tincture is prepared from the following main raw materials in parts by weight: 9-15 parts of common clubmoss herb, 8-15 parts of clematis root, 15-30 parts of kudzuvine root, 9-12 parts of Japanese polypody rhizome, 5-10 parts of Chinese rhubarb, 8-16 parts of Chinese taxillus twig, 10-20 parts of cassia twig, 9-15 parts of liquorice root, 8-16 parts of bitter orange, 9-15 parts of largetrifoliolious bugbane rhizome, 6-9 parts of herb of Japanese betony, 3-6 parts of dragon's blood, 6-12 parts of turmeric, 10-15 parts of kusnezoff monkshood root and 12-16 parts of fortune's drynaria rhizome. The tincture disclosed by the invention takes the principle of traditional Chinese medicine for treating bone injuries as basis, and adopts an external coating mode to ensure that medicines directly act on injured parts by virtue of local penetration of the medicines, so that weak medicine effects of oral administration medicines and relatively large side effects on a human body caused by the oral administration medicines can be avoided, and injures can be eliminated more rapidly; and the tincture is a novel prescription for treating the bone injuries with significant curative effects.

Description

A kind of promotion bone injury healing tincture and preparation method
Technical field
The present invention relates to traditional Chinese medicine field, especially relate to a kind of promotion bone injury healing tincture and preparation method.
Background technology
Bone injury polyphalangism is rolled over, and fracture is integrity and the seriality interruption of phalanges, due to a kind of disease that the reason such as wound or internal injury causes bone parts ground or fully ruptures.Be more common in child and old people, the young and the middle aged also happens occasionally.All can fracture in each position of whole body, but modal or extremity fracture.The main clinical manifestation of fracture is: have localized pain and tenderness, swelling and occur ecchymosis, limb function position or completely lose, and completeness sclerotin still can occur cacomelia and abnormal movement.Patient is often-individual position fracture, and minority is multiple fracture, and through appropriate process in time, most patient can recover original function, and a few patients can leave sequela in various degree.Fracture is divided into closure and open two large classes usually.Closed fracture refers to that skin soft tissue is relatively complete, and fracture end is not yet communicated with the external world; Open fracture then refers to that fracture has wound, and fracture end is in communication with the outside.The general manifestation of bone injury: heating paresthesia, after fracture, general body temperature is normal, the fracture that amount of bleeding is larger, and during absorption of hematoma, body temperature slightly raises, but is generally no more than 38 DEG C, when open fracture body temperature raises, should consider the possibility infected.Produce shock symptom, the shock main cause caused by fracture is hemorrhage, particularly fracture of pelvis, Fracture of femur and multiple fracture, and the large person of its amount of bleeding can reach more than 2000ml.Also shock can be caused when serious open fracture or concurrent important internal organs damage.Topical manifestations: generally show as local pain, swelling and dysfunction.During fracture, bone marrow, periosteum and surrounding tissue angiorrhexis are hemorrhage, form hematoma at fracture, and edema caused by soft tissue injury, make suffering limb serious swelling, even occurring tension vesicle and ecchymosis, due to the decomposition of hemoglobin, can be purple, cyan or yellow.Having an intense pain appears in fracture local, aggravates when particularly moving suffering limb.Local swelling and pain make suffering limb limitation of activity, and complete fracture can make injured limb movable function completely lose.
In the method for existing Chinese traditional treatment bone injury, publication number CN 101496875 A(application number 200910111294.4) patent discloses a kind of external-use medical ointment for bone fracture, be blended into Mel by the mixed uniformly medicine loose powder of weight components with the part by weight of 1:1.7-2.0 and mix the ointment made thoroughly: Dahurian Angelica Root 8-11 part, Rhubarb 3-7 part, Cape Jasmine Fruit 8-11 part, frankincense 3-7 part, Myrrh 3-7 part, Radix Paeoniae Rubra powder 3-7 part, saffron powder 3-7 part.Publication number CN 103417780 A(application number 201310343421.X) the plaster that patent discloses a kind of set a broken bone, by according to parts by weight: Stigma Croci 18-22 part, Radix Aconiti 28-32 part, Rhizoma Arisaematis 18-22 part, Rhizoma Pinelliae 18-22 part, Olibanum 38-42 part, Myrrha 38-42 part, eupolyphaga 48-52 part, Sanguis Draxonis 28-32 part, Pyritum (calcined) 28-32 part, Herba Artemisiae Anomalae 58-62 part, Radix Dipsaci 58-62 part, hydrargrum oxydatum crudum 1000-1500 part and Oleum Sesami 2000-3000 part are made.Publication number CN 101933999 A(application number 200910065367.0) the medicine that patent discloses a kind of set a broken bone, be prepared from by the raw material of following weight parts: Radix Codonopsis 10-15, Poria 10-15, Fructus Lycii 10-15, Rhizoma Atractylodis Macrocephalae 8-12, Radix Salviae Miltiorrhizae 15-20, Fructus Chaenomelis 8-12, Radix Achyranthis Bidentatae 10-15, Radix Angelicae Sinensis 8-12, Flos Carthami 5-10.
Mostly fracture is what unexpected injury caused, and in the modern life of high speed development, sudden hurt accident is recurrent.But doctor trained in Western medicine is unsatisfactory in treatment, the serious bone injury mode adopting operation more, cut fixing, its course for the treatment of is long, recover slowly, and side effect is larger; The time that naturopathy needs is also veryer long, and the patient of significant proportion can have serious sequela, and doctor trained in Western medicine aspect does not have specific drug yet, and be mostly antibiotic medicine, side effect is very large.
Summary of the invention
An object of the present invention is that providing a kind of promotes bone injury healing tincture, it adopts Chinese crude drug comparatively common to be in the localities raw material, there is the effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, bone and muscle strengthening, adjustment bone metabolism, can effectively increase osteoclast number and activity, promote New born formation, significantly can increase bone density, rebuild bone micro-structure comprehensively, promote callus formation, obviously shorten bone injury recovery time.Another object is just to provide the preparation method of above-mentioned promotion bone injury healing tincture.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of promotion bone injury healing tincture, takes off the primary raw material stating weight proportion and is prepared from: Herba Lycopodii 9-15 part; Radix Clematidis 8-15 part; Radix Puerariae 15-30 part; Rhizoma Polypodiodis Nipponicae 9-12 part; Radix Et Rhizoma Rhei 5-10 part; Herba Taxilli 8-16 part; Ramulus Cinnamomi 10-20 part; Radix Glycyrrhizae 9-15 part; Fructus Aurantii 8-16 part; Rhizoma Cimicifugae 9-15 part; Herba Stachydis Japonicae 6-9 part; Sanguis Draxonis 3-6 part; Rhizoma Curcumae Longae 6-12 part; Radix Aconiti Kusnezoffii 10-15 part; Rhizoma Drynariae 12-16 part.
A kind of promotion bone injury healing tincture, preferred scheme is, takes off the primary raw material stating weight proportion and is prepared from: Herba Lycopodii 11-13 part; Radix Clematidis 10-13 part; Radix Puerariae 20-25 part; Rhizoma Polypodiodis Nipponicae 10-11 part; Radix Et Rhizoma Rhei 6-9 part; Herba Taxilli 11-13 part; Ramulus Cinnamomi 13-17 part; Radix Glycyrrhizae 11-13 part; Fructus Aurantii 11-13 part; Rhizoma Cimicifugae 11-13 part; Herba Stachydis Japonicae 7-8 part; Sanguis Draxonis 4-5 part; Rhizoma Curcumae Longae 8-10 part; Radix Aconiti Kusnezoffii 11-14 part; Rhizoma Drynariae 13-15 part.
A kind of promotion bone injury healing tincture, the scheme be more preferably is, takes off the primary raw material stating weight proportion and is prepared from: Herba Lycopodii 12 parts; Radix Clematidis 12 parts; Radix Puerariae 22 parts; Rhizoma Polypodiodis Nipponicae 10.5 parts; Radix Et Rhizoma Rhei 8 parts; Herba Taxilli 12 parts; Ramulus Cinnamomi 15 parts; 12 parts, Radix Glycyrrhizae; Fructus Aurantii 12 parts; Rhizoma Cimicifugae 12 parts; Herba Stachydis Japonicae 7.5 parts; Sanguis Draxonis 4.5 parts; 9 parts, Rhizoma Curcumae Longae; Radix Aconiti Kusnezoffii 12 parts; Rhizoma Drynariae 14 parts.
The preparation method of above-mentioned promotion bone injury healing tincture, step is as follows:
(1) by Radix Aconiti Kusnezoffii soak with ethanol 4-6 hour, filter, obtain soak;
(2) smashed by Sanguis Draxonis, be placed in pot, add clear water, slow fire heats, and heats while stirring to Sanguis Draxonis and melts completely;
(3) in pot, watch core paper is completed, add water-wet, Herba Lycopodii, Radix Glycyrrhizae, Fructus Aurantii and Herba Stachydis Japonicae are layered on watch core paper, slow fire is heated to paper and has done cigarette close to time shrivelled, constantly stir medical material 10-20 minute, stop heating, cooling, pulverize, cross 100-140 mesh sieve, be placed in glass container, add step (1)-(2) gained medicinal liquid, soak 2-3 days;
(4) by Radix Clematidis, Radix Puerariae, Rhizoma Polypodiodis Nipponicae, Radix Et Rhizoma Rhei, Herba Taxilli, Ramulus Cinnamomi, Rhizoma Cimicifugae, Rhizoma Curcumae Longae and Rhizoma Drynariae section, be placed in glass container, soak 5-7 days with wine, every day rocks 3-6 time;
(5) by step (3)-(4) gains mix homogeneously, leave standstill 1-2 days, filter, be concentrated into 1/2 of original volume.
The preparation method of above-mentioned promotion bone injury healing tincture, preferred scheme is: step (1) preferably service property (quality) concentration is the ethanol of 30%-40%, consumption is 2-4 times of Radix Aconiti Kusnezoffii quality, and be more preferably the ethanol that service property (quality) concentration is 35%, consumption is 3 times of Radix Aconiti Kusnezoffii quality.
The preparation method of above-mentioned promotion bone injury healing tincture, preferred scheme is: the consumption of the preferred clear water of step (2) is 2-4 times of Sanguis Draxonis quality, and the consumption being more preferably clear water is 3 times of Sanguis Draxonis quality.
The preparation method of above-mentioned promotion bone injury healing tincture, preferred scheme is: step (3) preferably constantly stirs medical material 13-17 minute, is more preferably and constantly stirs medical material 15 minutes.
The preparation method of above-mentioned promotion bone injury healing tincture, preferred scheme is: step (3) is preferred crosses 110-130 mesh sieve, is more preferably 120 mesh sieves.
The preparation method of above-mentioned promotion bone injury healing tincture, preferred scheme is: step (4) is preferably cut into the lamellar of thick 2.5-3.5mm, is more preferably the lamellar being cut into thick 3mm.
The preparation method of above-mentioned promotion bone injury healing tincture, preferred scheme is: the consumption of the preferred wine of step (4) is 3-5 times of quality of medicinal material after section, and the consumption being more preferably wine is 4 times of quality of medicinal material after section.
using method: for making the present invention reach optimum therapeuticing effect, cleaned by sore place and dry, this product is applied to affected part, being often coated with 3-5 time beyond the highest heavens, 7 days is a course for the treatment of.
Beneficial effect of the present invention is embodied in:
The present invention promotes that bone injury healing tincture is based on the principle of Chinese traditional treatment bone injury, adopt the mode of external application, by the local penetration of medicine, medicine is made to be applied directly to injury, thus the effective ingredient of medicine is directly sent to lesions position, avoid the drug effect of oral medicine faint and larger side effect is caused to health, eliminate damage quickly.Effective ingredient can penetrate skin generation and invigorate blood circulation, pain relieving, and change and become silted up, stimulate the menstrual flow away network, the effects such as deep, expelling wind and cold of having one's ideas straightened out.Bone and muscle strengthening preferably, Liver and kidney is with mending, and spleen invigorating of nourishing blood, regulates bone metabolism, can effectively increase osteoclast number and activity, promote New born formation, significantly can not only increase bone density, bone micro-structure can also be rebuild comprehensively, promote callus formation, obviously shorten healing time.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1a kind of promote bone injury healing tincture, take off and state primary raw material and be prepared from (getting 30g for every part): Herba Lycopodii 9 parts; Radix Clematidis 8 parts; Radix Puerariae 15 parts; Rhizoma Polypodiodis Nipponicae 9 parts; Radix Et Rhizoma Rhei 5 parts; Herba Taxilli 8 parts; Ramulus Cinnamomi 10 parts; 9 parts, Radix Glycyrrhizae; Fructus Aurantii 8 parts; Rhizoma Cimicifugae 9 parts; Herba Stachydis Japonicae 6 parts; Sanguis Draxonis 3 parts; 6 parts, Rhizoma Curcumae Longae; Radix Aconiti Kusnezoffii 10 parts; Rhizoma Drynariae 12 parts.
A kind of promotion bone injury healing tincture preparation process is as follows:
(1) by Radix Aconiti Kusnezoffii soak with ethanol 4 hours, filter, obtain soak;
(2) smashed by Sanguis Draxonis, be placed in pot, add clear water, slow fire heats, and heats while stirring to Sanguis Draxonis and melts completely;
(3) in pot, watch core paper is completed, add water-wet, Herba Lycopodii, Radix Glycyrrhizae, Fructus Aurantii and Herba Stachydis Japonicae are layered on watch core paper, slow fire is heated to paper and has done cigarette close to time shrivelled, constantly stir medical material 10 minutes, stop heating, cooling, pulverize, cross 100 mesh sieves, be placed in glass container, add step (1)-(2) gained medicinal liquid, soak 2 days;
(4) by Radix Clematidis, Radix Puerariae, Rhizoma Polypodiodis Nipponicae, Radix Et Rhizoma Rhei, Herba Taxilli, Ramulus Cinnamomi, Rhizoma Cimicifugae, Rhizoma Curcumae Longae and Rhizoma Drynariae section, be placed in glass container, soak 5 days with wine, rock 3 every day;
(5) by step (3)-(4) gains mix homogeneously, leave standstill 1 day, filter, be concentrated into 1/2 of original volume.
Using method: cleaned by sore place and dry, this product is applied to affected part, be often coated with 3-5 time beyond the highest heavens, 7 days is a course for the treatment of.
embodiment 2a kind of promote bone injury healing tincture, take off and state primary raw material and be prepared from (getting 20g for every part): Herba Lycopodii 15 parts; Radix Clematidis 15 parts; Radix Puerariae 30 parts; Rhizoma Polypodiodis Nipponicae 12 parts; Radix Et Rhizoma Rhei 10 parts; Herba Taxilli 16 parts; Ramulus Cinnamomi 20 parts; Radix Glycyrrhizae 9-15 part; Fructus Aurantii 16 parts; Rhizoma Cimicifugae 15 parts; Herba Stachydis Japonicae 9 parts; Sanguis Draxonis 6 parts; 12 parts, Rhizoma Curcumae Longae; Radix Aconiti Kusnezoffii 15 parts; Rhizoma Drynariae 16 parts.
A kind of promotion bone injury healing tincture preparation process is as follows:
(1) by Radix Aconiti Kusnezoffii soak with ethanol 6 hours, filter, obtain soak;
(2) smashed by Sanguis Draxonis, be placed in pot, add clear water, slow fire heats, and heats while stirring to Sanguis Draxonis and melts completely;
(3) in pot, watch core paper is completed, add water-wet, Herba Lycopodii, Radix Glycyrrhizae, Fructus Aurantii and Herba Stachydis Japonicae are layered on watch core paper, slow fire is heated to paper and has done cigarette close to time shrivelled, constantly stir medical material 20 minutes, stop heating, cooling, pulverize, cross 140 mesh sieves, be placed in glass container, add step (1)-(2) gained medicinal liquid, soak 3 days;
(4) by Radix Clematidis, Radix Puerariae, Rhizoma Polypodiodis Nipponicae, Radix Et Rhizoma Rhei, Herba Taxilli, Ramulus Cinnamomi, Rhizoma Cimicifugae, Rhizoma Curcumae Longae and Rhizoma Drynariae section, be placed in glass container, soak 7 days with wine, rock 6 every day;
(5) by step (3)-(4) gains mix homogeneously, leave standstill 2 days, filter, be concentrated into 1/2 of original volume.
Using method: cleaned by sore place and dry, this product is applied to affected part, be often coated with 3-5 time beyond the highest heavens, 7 days is a course for the treatment of.
model case onewei, XX, male, 25 years old, Weifang City of Shandong Province from Changyue County.Broken by the right hand because of carelessness when playing ball in court, hurt like hell, the right hand scratches the swelling of proximal bone blood stasis, and activity is obstructed.Hospital diagnosis is gone to be handle dislocation.Injury and bone fracture application compress are used, swelling position DeGrain after a week after non-operative treatment resets.
After using gained of the present invention to promote bone injury healing tincture (embodiment 2) 1 course for the treatment of, pain obviously alleviates, and when changing dressings, blood stasis swelling is disappeared a greater part of, and swelling obviously disappears to the greatest extent.To continue after 1 course for the treatment of of use without pain, check and learn and be almost recovered, can activity freely.Use consolidate 1 course for the treatment of again.Without all untoward reaction during medication, not by any other Chinese medicine and western medicine, patent medicine auxiliary treatment.
embodiment 3a kind of promote bone injury healing tincture, take off and state primary raw material and be prepared from (getting 50g for every part): Herba Lycopodii 11 parts; Radix Clematidis 10 parts; Radix Puerariae 20 parts; Rhizoma Polypodiodis Nipponicae 10 parts; Radix Et Rhizoma Rhei 6 parts; Herba Taxilli 11 parts; Ramulus Cinnamomi 13 parts; 11 parts, Radix Glycyrrhizae; Fructus Aurantii 11 parts; Rhizoma Cimicifugae 11 parts; Herba Stachydis Japonicae 7 parts; Sanguis Draxonis 4 parts; 8 parts, Rhizoma Curcumae Longae; Radix Aconiti Kusnezoffii 11 parts; Rhizoma Drynariae 13 parts.
A kind of promotion bone injury healing tincture preparation process is as follows:
(1) by Radix Aconiti Kusnezoffii soak with ethanol 4 hours, filter, obtain soak;
(2) smashed by Sanguis Draxonis, be placed in pot, add clear water, slow fire heats, and heats while stirring to Sanguis Draxonis and melts completely;
(3) in pot, watch core paper is completed, add water-wet, Herba Lycopodii, Radix Glycyrrhizae, Fructus Aurantii and Herba Stachydis Japonicae are layered on watch core paper, slow fire is heated to paper and has done cigarette close to time shrivelled, constantly stir medical material 13 minutes, stop heating, cooling, pulverize, cross 110 mesh sieves, be placed in glass container, add step (1)-(2) gained medicinal liquid, soak 2 days;
(4) by Radix Clematidis, Radix Puerariae, Rhizoma Polypodiodis Nipponicae, Radix Et Rhizoma Rhei, Herba Taxilli, Ramulus Cinnamomi, Rhizoma Cimicifugae, Rhizoma Curcumae Longae and Rhizoma Drynariae section, be placed in glass container, soak 5 days with wine, rock 3 every day;
(5) by step (3)-(4) gains mix homogeneously, leave standstill 1 day, filter, be concentrated into 1/2 of original volume.
Using method: cleaned by sore place and dry, this product is applied to affected part, be often coated with 3-5 time beyond the highest heavens, 7 days is a course for the treatment of.
embodiment 4a kind of promote bone injury healing tincture, take off and state primary raw material and be prepared from (getting 20g for every part): Herba Lycopodii 13 parts; Radix Clematidis 13 parts; Radix Puerariae 25 parts; Rhizoma Polypodiodis Nipponicae 11 parts; Radix Et Rhizoma Rhei 9 parts; Herba Taxilli 13 parts; Ramulus Cinnamomi 17 parts; 13 parts, Radix Glycyrrhizae; Fructus Aurantii 13 parts; Rhizoma Cimicifugae 13 parts; Herba Stachydis Japonicae 8 parts; Sanguis Draxonis 5 parts; 10 parts, Rhizoma Curcumae Longae; Radix Aconiti Kusnezoffii 14 parts; Rhizoma Drynariae 15 parts.
A kind of promotion bone injury healing tincture preparation process is as follows:
(1) by Radix Aconiti Kusnezoffii soak with ethanol 6 hours, filter, obtain soak;
(2) smashed by Sanguis Draxonis, be placed in pot, add clear water, slow fire heats, and heats while stirring to Sanguis Draxonis and melts completely;
(3) in pot, watch core paper is completed, add water-wet, Herba Lycopodii, Radix Glycyrrhizae, Fructus Aurantii and Herba Stachydis Japonicae are layered on watch core paper, slow fire is heated to paper and has done cigarette close to time shrivelled, constantly stir medical material 17 minutes, stop heating, cooling, pulverize, cross 130 mesh sieves, be placed in glass container, add step (1)-(2) gained medicinal liquid, soak 3 days;
(4) by Radix Clematidis, Radix Puerariae, Rhizoma Polypodiodis Nipponicae, Radix Et Rhizoma Rhei, Herba Taxilli, Ramulus Cinnamomi, Rhizoma Cimicifugae, Rhizoma Curcumae Longae and Rhizoma Drynariae section, be placed in glass container, soak 7 days with wine, rock 6 every day;
(5) by step (3)-(4) gains mix homogeneously, leave standstill 2 days, filter, be concentrated into 1/2 of original volume.
Using method: cleaned by sore place and dry, this product is applied to affected part, be often coated with 3-5 time beyond the highest heavens, 7 days is a course for the treatment of.
model case twodesolate XX, female, 45 years old, peasant, Langfang City people from Sanhe City, Hebei province.Once descending in the way on ground, accidentally throw from car, when throwing, the left hand palm lands, and carpal joint is dorsiflexion position, namely causes left wrist to swell and ache, limitation of activity.Look into: obvious limitation swelling after left elbow, subcutaneous have large stretch of ecchymosis, and unusual pain during touching, freely can not stretch song.X-ray display fracture, fracture line is oblique.Whole body number place is red and swollen, and left foot condyle bone place redness is blue, processes in hospital, still without positive effect after one week, has number place blood stasis.
After using gained of the present invention to promote bone injury healing tincture (embodiment 4) 1 course for the treatment of, left wrist pain obviously alleviates, the cancellation of lighter congestion, and more serious congestion also obviously diminishes thin out.After continuing 1 course for the treatment of of use, red and swollen blood stasis disperses, but and oneself walks.After adhering to again 1 course for the treatment of of use, the whole cancellation of congestion, left wrist can stretch song flexibly, also can normally walk, clinical recovery.Without all untoward reaction during medication.
embodiment 5a kind of promote bone injury healing tincture, take off and state primary raw material and be prepared from (getting 10g for every part): Herba Lycopodii 12 parts; Radix Clematidis 12 parts; Radix Puerariae 22 parts; Rhizoma Polypodiodis Nipponicae 10.5 parts; Radix Et Rhizoma Rhei 8 parts; Herba Taxilli 12 parts; Ramulus Cinnamomi 15 parts; 12 parts, Radix Glycyrrhizae; Fructus Aurantii 12 parts; Rhizoma Cimicifugae 12 parts; Herba Stachydis Japonicae 7.5 parts; Sanguis Draxonis 4.5 parts; 9 parts, Rhizoma Curcumae Longae; Radix Aconiti Kusnezoffii 12 parts; Rhizoma Drynariae 14 parts.
A kind of promotion bone injury healing tincture preparation process is as follows:
(1) by Radix Aconiti Kusnezoffii soak with ethanol 5 hours, filter, obtain soak;
(2) smashed by Sanguis Draxonis, be placed in pot, add clear water, slow fire heats, and heats while stirring to Sanguis Draxonis and melts completely;
(3) in pot, watch core paper is completed, add water-wet, Herba Lycopodii, Radix Glycyrrhizae, Fructus Aurantii and Herba Stachydis Japonicae are layered on watch core paper, slow fire is heated to paper and has done cigarette close to time shrivelled, constantly stir medical material 15 minutes, stop heating, cooling, pulverize, cross 120 mesh sieves, be placed in glass container, add step (1)-(2) gained medicinal liquid, soak 3 days;
(4) by Radix Clematidis, Radix Puerariae, Rhizoma Polypodiodis Nipponicae, Radix Et Rhizoma Rhei, Herba Taxilli, Ramulus Cinnamomi, Rhizoma Cimicifugae, Rhizoma Curcumae Longae and Rhizoma Drynariae section (being cut into the lamellar of thick 3mm), be placed in glass container, soak 6 days with wine (consumption of wine is 4 times of quality of medicinal material after section), rock 5 every day;
(5) by step (3)-(4) gains mix homogeneously, leave standstill 2 days, filter, be concentrated into 1/2 of original volume.
Using method: cleaned by sore place and dry, this product is applied to affected part, be often coated with 3-5 time beyond the highest heavens, 7 days is a course for the treatment of.
The pharmacological effect of each crude drug is respectively:
Herba Lycopodii: mildly bitter flavor, pungent, warm in nature.Return liver,spleen,kidney warp.For the dry herb of lycopsid Lycopodium clavatum.There is expelling wind and removing dampness, effect of relaxing muscles and tendons and activating QI and blood in the collateral.For joint aches, joint stuffiness.
Radix Clematidis: acrid in the mouth, salty, warm in nature.Return urinary bladder channel.For the dry root and rhizome of ranunculaceae plant Radix Clematidis, Clematis hexapetala or northeast clematis.There is expelling wind and removing dampness, effect of removing obstruction in the collateral to relieve pain.For rheumatic arthralgia. numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone chokes down larynx.
Radix Puerariae: sweet in the mouth, pungent, cool in nature.Return spleen, stomach warp.For the dry root of legume pueraria lobata, practise and claim Herba Gelsemii Elegantis.There is expelling pathogenic factors from muscles for reducing heat, promote the production of body fluid, rash, effect of yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Rhizoma Polypodiodis Nipponicae: mildly bitter flavor, cool in nature.For fern Polypodiaceae Polypodiodes plant Rhizoma Polypodiodis Nipponicae is rhizome.Containing polytype triterpenoid, belong to having of hopane type in base: 22(29)-hopenen, 21-hopenen, 17(21)-hopenen, 17 β, what handkerchief alkane, dryopteris crassirhizoma Nakai alcohol, dryopteris crassirhizoma Nakai alcohol acetic ester, He Pa-22-alcohol, 13(18 of 21 beta epoxides)-neohopene, 8-fernene, 7-fernene, 7,9(11)-fernadiene, 17 α H-tri-nor-He Pa-21-ketone; Belong to having of oleanane type: 18-oleanene, 12-oleanene, 11,13(18)-olive diene, germanicol acetas etc.Promoting flow of QI and blood, detumescence dissipating blood stasis.Control traumatic injury, impairment caused by overstrain, lumbago and skelalgia, hemiplegia, tinea alba.
Radix Et Rhizoma Rhei: bitter in the mouth, cold in nature.Return stomach, large intestine, liver, spleen channel.For the dry root and rhizome of section of family plant sorrel, Rheum tanguticum or Rheum officinale.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, effect of removing toxic substances.For solid cubic content constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting, spits blood, spitting of blood, and epistaxis, has blood in stool, hematuria; Blood-retention, amenorrhea, stomachache of being retarded by silt puerperal ， lumps in the chest and abdomen, traumatic injury, pyretic toxicity carbuncle and ulcer, erysipelas, scalds.
Herba Taxilli: bitter in the mouth, sweet, property is put down.Return liver, kidney channel.For Loranthaceae plant kills the dry stem and branch with leaf of parasitic youngster.There is invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, effect of antiabortive unit.For rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement, hypertension.
Ramulus Cinnamomi: acrid in the mouth, sweet, warm in nature.GUIXIN, lung, urinary bladder channel.For the dry twig of canella Cortex Cinnamomi.There is diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, effect of the flat gas that spins.For anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Radix Glycyrrhizae: sweet in the mouth, property is put down.GUIXIN.Lung, spleen, stomach warp.For the dry root and rhizome of glycyrrhizic legume, Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L..There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, effect of coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of institute's abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity.
Fructus Aurantii: bitter in the mouth, pungent, sour, warm in nature.For the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.Return spleen, stomach warp.There is regulating the flow of QI to ease the stomach, effect of the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention, gastroptosis, proctoptosis, uterine prolapse.
Rhizoma Cimicifugae: acrid in the mouth, micro-sweet, cold nature.For the dry rhizome of ranunculaceae plant C.heracleifolia, Cimicifuga Dahurica or Rhizoma Cimicifugae.Return lung, spleen, stomach, large intestine channel.Have and deliver rash, heat-clearing and toxic substances removing, effect of elevate a turnable ladder yang-energy.For headache due to pathogenic wind-heat, toothache, aphtha, laryngopharynx swelling and pain, measles without adequate eruption, YANG toxin syndrome sends out speckle, proctoptosis, uterine prolapse.
Herba Stachydis Japonicae: acrid in the mouth, slightly warm in nature.Return intestinal, stomach, lung meridian.For the herb of labiate Herba Stachydis Japonicae.There is dispelling wind regulate the flow of vital energy, effect of hemostasis and anti-inflammation.For flu, acute filthy disease, consumptive lung disease, lung abscess, wind syndrome of head is dizzy, halitosis, pharyngalgia, dysentery, postpartum apoplexy, spits blood, epistaxis, metrorrhagia, stranguria with blood, traumatic injury.
Sanguis Draxonis: sweet in the mouth, salty, property is put down.GUIXIN, Liver Channel.The resin oozed out for babassu Sanguis Draxonis fruit is through being processed into.There is removing blood stasis and relieving pain, effect of hemostasia and promoting granulation.Lose for falling to flutter, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury.
Rhizoma Curcumae Longae: acrid in the mouth, hardship, warm in nature.Return spleen, Liver Channel.For the dry rhizome of zingiberaceous plant Rhizoma Curcumae Longae.There is removing blood stasis circulation of qi promoting, effect of inducing menstruation to relieve menalgia.For the twinge of the breast side of body, amenorrhea ， mass in the abdomen, rheumatism shoulder arm pain, tumbling and swelling.
Radix Aconiti Kusnezoffii: acrid in the mouth, hardship, hot in nature.GUIXIN, liver,kidney,spleen warp.For the dried root of ranunculaceae plant Aconitum kusnezoffii Reichb.There is expelling wind and removing dampness, effect of antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Rhizoma Drynariae: bitter in the mouth, warm in nature.Return kidney, Liver Channel.For the dry rhizome of Plants of Polypodiaceae Mongolian oak Herba pteridii latiusculi.There is the kidney invigorating bone strengthening, continuous effect of hindering pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.
test example: in order to verify that gained of the present invention promotes the curative effect of bone injury healing tincture (embodiment 5): in October ,-2010 in June, 2009, screen 250 routine patient with bone fracture in Duo Suo hospital, wherein women 94 example, male 156 example, max age 74 years old, minimal ages 9 years old.Be divided into experimental group and matched group two groups (wherein experimental group has 150 people, and matched group has 100 people) at random.Experimental group uses gained of the present invention to promote bone injury healing tincture, and using method is: cleaned by sore place and dry, this product is applied to affected part, be often coated with 3-5 time beyond the highest heavens, 7 days is a course for the treatment of.Matched group uses other medicine (as traumatology spirit tablet for curing fracture etc.), be grown up one time 4; Ten years old to 14 years old child one time 3, the child one time of less than ten years old 2,3 times on the one.Curative effect situation criterion: cure: the transference cure such as congestion, pain, recovers normal.Effective: the symptom such as congestion, pain obviously alleviates or partial disappearance.Invalid: the various malaise symptoms such as congestion, pain is unchanged.Result is as shown in table 1 below:
Table 1
therapeutic effect: use gained of the present invention to promote healing 108 people of bone injury healing tincture, cure rate is up to 72%, and effective 39 people, effective percentage 26%, invalid 3 people, total effective rate reaches 98%.And using healing 43 people of other products, cure rate only reaches 43%, effective 42 people, and invalid number is but up to 15 people, and inefficiency reaches 15%, effective percentage only 85%.The effect using and promote that the successful of bone injury healing tincture is better than using other products can be found out.The present invention promotes that bone injury healing tincture is based on the principle of Chinese traditional treatment bone injury, adopt externally applied formulation, by the local penetration of medicine, medicine is made to be applied directly to injury, thus the effective ingredient of medicine is directly sent to lesions position, avoid the drug effect of oral medicine faint and larger side effect is caused to health, eliminate damage quickly, be set a broken bone new prescription evident in efficacy, bring Gospel to vast patient with bone fracture.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. promote a bone injury healing tincture, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Herba Lycopodii 9-15 part; Radix Clematidis 8-15 part; Radix Puerariae 15-30 part; Rhizoma Polypodiodis Nipponicae 9-12 part; Radix Et Rhizoma Rhei 5-10 part; Herba Taxilli 8-16 part; Ramulus Cinnamomi 10-20 part; Radix Glycyrrhizae 9-15 part; Fructus Aurantii 8-16 part; Rhizoma Cimicifugae 9-15 part; Herba Stachydis Japonicae 6-9 part; Sanguis Draxonis 3-6 part; Rhizoma Curcumae Longae 6-12 part; Radix Aconiti Kusnezoffii 10-15 part; Rhizoma Drynariae 12-16 part.
2. promotion bone injury healing tincture according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Herba Lycopodii 11-13 part; Radix Clematidis 10-13 part; Radix Puerariae 20-25 part; Rhizoma Polypodiodis Nipponicae 10-11 part; Radix Et Rhizoma Rhei 6-9 part; Herba Taxilli 11-13 part; Ramulus Cinnamomi 13-17 part; Radix Glycyrrhizae 11-13 part; Fructus Aurantii 11-13 part; Rhizoma Cimicifugae 11-13 part; Herba Stachydis Japonicae 7-8 part; Sanguis Draxonis 4-5 part; Rhizoma Curcumae Longae 8-10 part; Radix Aconiti Kusnezoffii 11-14 part; Rhizoma Drynariae 13-15 part.
3. promotion bone injury healing tincture according to claim 1, is characterized in that, takes off the primary raw material stating weight proportion and is prepared from: Herba Lycopodii 12 parts; Radix Clematidis 12 parts; Radix Puerariae 22 parts; Rhizoma Polypodiodis Nipponicae 10.5 parts; Radix Et Rhizoma Rhei 8 parts; Herba Taxilli 12 parts; Ramulus Cinnamomi 15 parts; 12 parts, Radix Glycyrrhizae; Fructus Aurantii 12 parts; Rhizoma Cimicifugae 12 parts; Herba Stachydis Japonicae 7.5 parts; Sanguis Draxonis 4.5 parts; 9 parts, Rhizoma Curcumae Longae; Radix Aconiti Kusnezoffii 12 parts; Rhizoma Drynariae 14 parts.
4., according to the preparation method of the arbitrary described promotion bone injury healing tincture of claim 1-3, it is characterized in that, step is as follows:
(1) by Radix Aconiti Kusnezoffii soak with ethanol 4-6 hour, filter, obtain soak;
(2) smashed by Sanguis Draxonis, be placed in pot, add clear water, slow fire heats, and heats while stirring to Sanguis Draxonis and melts completely;
(3) in pot, watch core paper is completed, add water-wet, Herba Lycopodii, Radix Glycyrrhizae, Fructus Aurantii and Herba Stachydis Japonicae are layered on watch core paper, slow fire is heated to paper and has done cigarette close to time shrivelled, constantly stir medical material 10-20 minute, stop heating, cooling, pulverize, cross 100-140 mesh sieve, be placed in glass container, add step (1)-(2) gained medicinal liquid, soak 2-3 days;
(4) by Radix Clematidis, Radix Puerariae, Rhizoma Polypodiodis Nipponicae, Radix Et Rhizoma Rhei, Herba Taxilli, Ramulus Cinnamomi, Rhizoma Cimicifugae, Rhizoma Curcumae Longae and Rhizoma Drynariae section, be placed in glass container, soak 5-7 days with wine, every day rocks 3-6 time;
(5) by step (3)-(4) gains mix homogeneously, leave standstill 1-2 days, filter, be concentrated into 1/2 of original volume.
5. preparation method according to claim 4, is characterized in that: step (1) preferably service property (quality) concentration is the ethanol of 30%-40%, and consumption is 2-4 times of Radix Aconiti Kusnezoffii quality, and be more preferably the ethanol that service property (quality) concentration is 35%, consumption is 3 times of Radix Aconiti Kusnezoffii quality.
6. preparation method according to claim 4, is characterized in that: the consumption of the preferred clear water of step (2) is 2-4 times of Sanguis Draxonis quality, and the consumption being more preferably clear water is 3 times of Sanguis Draxonis quality.
7. preparation method according to claim 4, is characterized in that: step (3) preferably constantly stirs medical material 13-17 minute, is more preferably and constantly stirs medical material 15 minutes.
8. preparation method according to claim 4, is characterized in that: step (3) is preferred crosses 110-130 mesh sieve, is more preferably 120 mesh sieves.
9. preparation method according to claim 4, is characterized in that: step (4) is preferably cut into the lamellar of thick 2.5-3.5mm, is more preferably the lamellar being cut into thick 3mm.
10. preparation method according to claim 4, is characterized in that: the consumption of the preferred wine of step (4) is 3-5 times of quality of medicinal material after section, and the consumption being more preferably wine is 4 times of quality of medicinal material after section.
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