CN104524379A - Wind-dispelling spleen-invigorating dampness-removing tincture for treating arthritis and preparation method thereof - Google Patents
Wind-dispelling spleen-invigorating dampness-removing tincture for treating arthritis and preparation method thereof Download PDFInfo
- Publication number
- CN104524379A CN104524379A CN201510051263.XA CN201510051263A CN104524379A CN 104524379 A CN104524379 A CN 104524379A CN 201510051263 A CN201510051263 A CN 201510051263A CN 104524379 A CN104524379 A CN 104524379A
- Authority
- CN
- China
- Prior art keywords
- parts
- tincture
- rhizoma
- radix
- arthritis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/746—Morinda
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/902—Sparganiaceae (Bur-reed family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a wind-dispelling spleen-invigorating dampness-removing tincture for treating arthritis. The wind-dispelling spleen-invigorating dampness-removing tincture is prepared from the following raw material medicines in parts by weight: 15-20 parts of black-striped snake, 8-12 parts of szechuan lovage rhizome, 9-15 parts of Japanese polypody rhizome, 7-14 parts of codonopsis pilosula, 15-20 parts of kudzuvine root, 8-16 parts of atractylis lancea, 10-25 parts of medicinal indianmulberry root, 15-20 parts of green tangerine peel, 9-15 parts of bitter orange, 10-15 parts of largetrifoliolious bugbane rhizome, 12-20 parts of wild aconite root, 12-18 parts of fortune's drynaria rhizome, 8-10 parts of chloranthus holostegius, 10-20 parts of frankincense and 6-9 parts of common burreed rhizome. The wind-dispelling spleen-invigorating dampness-removing tincture disclosed by the invention also shows the excellent effects as follows: the tincture is prepared by adopting a traditional Chinese medicine theoretical analysis prescription, and a preparation method of reasonable and stable active components is researched according to research results of physical and chemical properties and pharmacological action of components in each medicine; and the prescription can be used for removing swelling and easing pain, and can also be used for enhancing the effects of dispelling wind and removing dampness, and invigorating the spleen and replenishing qi. All selected materials are conventional traditional Chinese medicine materials, and cannot cause any toxic or side effects; and the medicine disclosed by the invention is researched by combining the newest modern scientific research achievements based on conventional traditional Chinese medicine treatment through syndrome differentiation, ensures that various medicines are combined for use, and has the characteristics of significant curative effects, safety, convenience and low cost.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture and preparation method.
Background technology
Joint is the significant points of support human body action, once wind and cold is wet invade joint tissue position, can cause that joint blood is obstructed to be obstructed, of a specified duration can produce rheumatism, rheumatoid arthritis.Rheumatism severe one, there will be arthroncus, activities adverse, apathetic symptom, severe patient can not be walked, and rheumatism pathological changes can occur, form migrans arthritis, the joint part of whole body may be invaded, as can not symptomatic treatment in time, by the physical and mental health of serious threat patient.
Chinese medicine is thought that wind and cold is damp and hot and is waited exopathogen to be the initiating agent bringing out arthritic conditions, evil in exopathogen priming, inside and outside combined pathogens and falling ill.As " during Plain Questions four, thorn is inverse from opinion ": " sun is had a surplus, sick BI-syndrome located in muscle, excessive cold invading middle-JIAO(the spleen and stomach)." Ming Dynasty Wang Yun paddy emphasizes the importance training spleen reinforcing soil in " the understanding record arthromyodynia of miscellaneous diseases ": " condition numbness person closes also, is that venation is puckery and declare logical machine less, and QI and blood is solidifying and the gesture that flows less, and the water tonifying YIN then raw sun of QI invigorating is strengthened in the non-throwing of method for the treatment of; Non-urgency is eager to ask Liver and kidney, then sincere in training spleen reinforcing soil, this is retired due to illness and does not shake also.If mud is mixed extremely in three gas, be the heresy that must stay, and engage in day and send an expedition against, then body reality person peace, and body void person endangers." in addition, taste are the soil of central authorities, change the source of life, can ascending the clear and descending the turbid, under reaching on leading to.Spleen soil is vigorous then can controlling the water circulation, phlegm-damp not life, and pent-up difficulty becomes.The autochthonal Jinsui River of spleen, gold is raw then can drive table, carrys out general trouble without exopathogen.The thick then vital organs of the human body of spleen soil are all prosperous, muscle arteries and veins, joint tonneau.But, the people of emptiness of spleen and stomach, or because of overstrain internal injury, or outer by cold-damp etc., all can cause stagnation of dampness due to deficiency of the spleen, transporting mistake department, disorder of QI movement.And the biochemical weary source of insufficiency of the spleen then QI and blood, muscle is not rich, and extremities joint loses supports, for a long time then deficiency of qi and blood, and muscles and bones blood vessels lose and moisten foster, and battalion defends to be lost in mediation, and exopathogen is then taken advantage of a weak point, and between muscle feeling pulse and falls ill.Therefore the turbid interior life of weakness of the spleen and stomach, deficiency of qi and blood, expectorant is the important pathogenesis of primary disease.
Application publication number CN 103040966 A(application number 201210541017.9) Chinese patent literature disclose a kind of Chinese medicine for the treatment of of arthritis, be made up of the material medicine of following weight: Radix Angelicae Pubescentis 30 grams, Radix Cyathulae 21 grams, the Cortex Eucommiae 21 grams, the Radix Paeoniae Alba 24 grams, Herba Lycopodii 18 grams, Fructus Psoraleae 18 grams, Rhizoma Et Radix Notopterygii 21 grams, Radix Saposhnikoviae 15 grams, Ramulus Cinnamomi 15 grams, Radix Aconiti Lateralis Preparata 12 grams, 12 grams, Radix Glycyrrhizae.Application publication number CN 104127571 A(application number 201410321188.X) Chinese patent literature disclose a kind of medicated wine for the treatment of rheumatoid arthritis,, by following weight raw material and rice wine is brewed forms: Radix Angelicae Sinensis 10g, Rhizoma Cimicifugae 10g, Flos Carthami 10g, Caulis Piperis Kadsurae 10g, Herba Schizonepetae 10g, DAHUOXUE 10g, Cortex Cinnamomi 10g, Radix Dipsaci 10g, Fructus Lycii 10g, Radix Achyranthis Bidentatae 10g, Rhizoma Chuanxiong 25g, Ramulus Cinnamomi 25g, Oostethus 25g, Cortex Acanthopancis 25g, Pericarpium Citri Reticulatae 25g, eight stupefied numb 25g, Olibanum 6g, Myrrha 6g, Radix Glycyrrhizae 6g.Application publication number CN 102397478 A(application number 201010289746.0) Chinese patent literature disclose a kind of Chinese medicine for the treatment of of arthritis, be made up of the material medicine of following proportioning: Rhizoma Gastrodiae 50-100 gram, Scorpio 150-200 gram, Radix Astragali 120-180 gram, Radix Rehmanniae 40-80 gram, Herba Asari 80-150 gram, Rhizoma Alismatis 200-250 gram, Radix Aconiti Preparata 300-45 gram.
At present for the treatment of arthritic conditions, doctor trained in Western medicine is mainly to relieve the pain medicine or make anesthesia needle, and to gastric irritation greatly, greatly, life-time service patient can not accept, and Western medicine generally can only take stopgap measures and can not effect a permanent cure in side effect; Though existing Chinese medicine untoward reaction is less, onset is slow, and the course for the treatment of is long, poor repeatability.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide one and prepare effective a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture simple, easy to use, safe.Curative effect of medication of the present invention is definitely convenient to Clinical practice.
Technical scheme of the present invention is:
A kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, is prepared from by following bulk drugs, is weight portion: Zaocys 15-20; Rhizoma Chuanxiong 8-12; Rhizoma Polypodiodis Nipponicae 9-15; Radix Codonopsis 7-14; Radix Puerariae 15-20; Atractylodes lancea (Thunb.) DC. 8-16; Radix Morindae Officinalis 10-25; Pericarpium Citri Reticulatae Viride 15-20; Fructus Aurantii 9-15; Rhizoma Cimicifugae 10-15; Radix Aconiti Kusnezoffii 12-20; Rhizoma Drynariae 12-18; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 8-10; Olibanum 10-20; Rhizoma Sparganii 6-9.
In preferred scheme, Zaocys 17-18; Rhizoma Chuanxiong 9-11; Rhizoma Polypodiodis Nipponicae 11-13; Radix Codonopsis 9-12; Radix Puerariae 17-18; Atractylodes lancea (Thunb.) DC. 10-14; Radix Morindae Officinalis 15-20; Pericarpium Citri Reticulatae Viride 17-18; Fructus Aurantii 11-13; Rhizoma Cimicifugae 12-13; Radix Aconiti Kusnezoffii 14-18; Rhizoma Drynariae 14-16; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 8.5-9.5; Olibanum 13-17; Rhizoma Sparganii 7-8.
Be more preferably, Zaocys 17.5; Rhizoma Chuanxiong 10; Rhizoma Polypodiodis Nipponicae 12; Radix Codonopsis 10.5; Radix Puerariae 17.5; Atractylodes lancea (Thunb.) DC. 12; Radix Morindae Officinalis 17.5; Pericarpium Citri Reticulatae Viride 17.5; Fructus Aurantii 12; Rhizoma Cimicifugae 12.5; Radix Aconiti Kusnezoffii 16; Rhizoma Drynariae 15; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 9; Olibanum 15; Rhizoma Sparganii 7.5.
A preparation method for arthritis dispelling wind invigorating spleen to remove dampness tincture, step is as follows:
(1) get Atractylodes lancea (Thunb.) DC. sheet, pull out (pulling out after preferably soaking 30 minutes with rice-washed water) after soaking 25-35 minute with rice-washed water, put heating in food steamer and steam thoroughly, take out dry, for subsequent use; Get Testa Tritici to be sprinkling upon in medicine of a warm nature pot, add Radix Morindae Officinalis when smoldering in pot, constantly stir-frying to powder is coke yellow, takes out, and sieve removes Testa Tritici, cools;
(2) Radix Aconiti Kusnezoffii is cleaned, is cut sheet, is placed in container, adds old Yoghourt and soaks, within every 30 minutes, stir once, mouth is tasted when having numb feeling in the tongue and is taken out, and rinses with a small amount of water, then in 55-65 DEG C of forced air drying 30 minutes (being preferable over 60 DEG C of forced air dryings 30 minutes), take out, for subsequent use;
(3) will clean respectively by remaining crude drug except Atractylodes lancea (Thunb.) DC., Radix Morindae Officinalis, Radix Aconiti Kusnezoffii, then be placed in 75 DEG C of hot-air driers dry, take out, then the crude drug after the process of same step (1)-(2) is together placed in pulverizer and pulverizes, mix homogeneously, sieves for subsequent use;
(4) in above-mentioned mixing fine powders, add the ethanol (preferably adding the ethanol of 7 times amount in above-mentioned mixing fine powders) of 5-9 times amount, sealing is soaked 10-20 days (preferably sealing immersion 15 days), jolting every day, then supernatant is got, add the ethanol of same concentrations to prescribed volume, leave standstill 10-20 hour (preferably leaving standstill 15 hours), filter by nonwoven gauze, fill, to obtain final product.
The preparation method of above-mentioned a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, preferred scheme is, the time adding the immersion of old Yoghourt in step (2) is 24-36 hour (time preferably adding the immersion of old Yoghourt is 28-32 hour, and the time adding the immersion of old Yoghourt be more preferably is 30 hours).
The preparation method of above-mentioned a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, preferred scheme is, the temperature adding the immersion of old Yoghourt in step (2) is 0-10 DEG C (temperature preferably adding the immersion of old Yoghourt is 3-7 DEG C, and the temperature adding the immersion of old Yoghourt be more preferably is 5 DEG C).
The preparation method of above-mentioned a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, preferred scheme is, in step (3), the time of hot air drying is 18-32 minute (time of preferred hot air drying is 22-28 minute, and the time of the hot air drying be more preferably is 25 minutes).
The preparation method of above-mentioned a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, preferred scheme is, the middle 50-110 mesh sieve excessively of step (3) (preferred 70-90 mesh sieve excessively, mistake 80 mesh sieve be more preferably).
The preparation method of above-mentioned a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, preferred scheme is, in step (4), the mass concentration of added ethanol is the mass concentration of the preferred added ethanol of 65%-95%(is 75%-85%, and the mass concentration of the added ethanol be more preferably is 80%).
The preparation method of above-mentioned a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, preferred scheme is, in step (4), the number of times of jolting every day is 2-6 time (number of times of preferred jolting every day is 3-5 time, and the number of times of jolting every day be more preferably is 4 times).
Scientific formula of the present invention, preparation method is simple, easy to use, Be very effective.In addition, excellent results of the present invention also shows:
1,the present invention uses theory of Chinese medical science to analyze prescription composition, and according to each physicochemical property of flavour of a drug ingredient and the result of study of pharmacological action, research obtains the preparation method of reasonable, stable active component;
2,this prescription, while reducing swelling and alleviating pain, strengthens dispelling wind dehumidifying, the taste of invigorating the spleen and replenishing QI.Selected materials is all Chinese medicine material, without any side effects;
3,medicine of the present invention develops in conjunction with latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment, and all medicines share, and has evident in efficacy, safe ready, cheap feature.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, is prepared from by following bulk drugs, is weight portion (50g/ part): Zaocys 15 parts; Rhizoma Chuanxiong 8 parts; Rhizoma Polypodiodis Nipponicae 9 parts; Radix Codonopsis 7 parts; Radix Puerariae 15 parts; Atractylodes lancea (Thunb.) DC. 8 parts; Radix Morindae Officinalis 10 parts; 15 parts, Pericarpium Citri Reticulatae Viride; Fructus Aurantii 9 parts; Rhizoma Cimicifugae 10 parts; Radix Aconiti Kusnezoffii 12 parts; Rhizoma Drynariae 12 parts; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 8 parts; Olibanum 10 parts; Rhizoma Sparganii 6 parts.
A kind of preparation method of arthritis dispelling wind invigorating spleen to remove dampness tincture is:
(1) get Atractylodes lancea (Thunb.) DC. sheet, pull out after soaking 25 minutes with rice-washed water, put heating in food steamer and steam thoroughly, take out dry, for subsequent use; Get Testa Tritici to be sprinkling upon in medicine of a warm nature pot, add Radix Morindae Officinalis when smoldering in pot, constantly stir-frying to powder is coke yellow, takes out, and sieve removes Testa Tritici, cools;
(2) Radix Aconiti Kusnezoffii is cleaned, is cut sheet, is placed in container, adds old Yoghourt and soaks 24 hours in 0 DEG C, and within every 30 minutes, stir once, mouth is tasted when having numb feeling in the tongue and taken out, and rinses with a small amount of water, then in 55 DEG C of forced air dryings 30 minutes, takes out, for subsequent use;
(3) will clean respectively by remaining crude drug except Atractylodes lancea (Thunb.) DC., Radix Morindae Officinalis, Radix Aconiti Kusnezoffii, and then be placed in 75 DEG C of hot-air driers dry 18 minutes, take out, then the crude drug after the process of same step (1)-(2) is together placed in pulverizer and pulverizes, mix homogeneously, crosses 50 mesh sieves, for subsequent use;
(4) mass concentration adding 5 times amount in above-mentioned mixing fine powders is the ethanol of 65%, sealing immersion 10 days, and jolting every day 2 times, then gets supernatant, adds the ethanol of same concentrations to prescribed volume, leaves standstill 10 hours, and filter by nonwoven gauze, fill, to obtain final product.
The using method of tincture of the present invention is: clean affected part, gets appropriate tincture of the present invention, even wiping affected part, every day three times, 10 days courses for the treatment of.
embodiment 2a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, is prepared from by following bulk drugs, is weight portion (30g/ part): Zaocys 20 parts; Rhizoma Chuanxiong 12 parts; Rhizoma Polypodiodis Nipponicae 15 parts; Radix Codonopsis 14 parts; Radix Puerariae 20 parts; Atractylodes lancea (Thunb.) DC. 16 parts; Radix Morindae Officinalis 25 parts; 20 parts, Pericarpium Citri Reticulatae Viride; Fructus Aurantii 15 parts; Rhizoma Cimicifugae 15 parts; Radix Aconiti Kusnezoffii 20 parts; Rhizoma Drynariae 18 parts; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 10 parts; Olibanum 20 parts; Rhizoma Sparganii 9 parts.
A kind of preparation method of arthritis dispelling wind invigorating spleen to remove dampness tincture is:
(1) get Atractylodes lancea (Thunb.) DC. sheet, pull out after soaking 35 minutes with rice-washed water, put heating in food steamer and steam thoroughly, take out dry, for subsequent use; Get Testa Tritici to be sprinkling upon in medicine of a warm nature pot, add Radix Morindae Officinalis when smoldering in pot, constantly stir-frying to powder is coke yellow, takes out, and sieve removes Testa Tritici, cools;
(2) Radix Aconiti Kusnezoffii is cleaned, is cut sheet, is placed in container, adds old Yoghourt and soaks 36 hours in 10 DEG C, and within every 30 minutes, stir once, mouth is tasted when having numb feeling in the tongue and taken out, and rinses with a small amount of water, then in 65 DEG C of forced air dryings 30 minutes, takes out, for subsequent use;
(3) will clean respectively by remaining crude drug except Atractylodes lancea (Thunb.) DC., Radix Morindae Officinalis, Radix Aconiti Kusnezoffii, and then be placed in 75 DEG C of hot-air driers dry 32 minutes, take out, then the crude drug after the process of same step (1)-(2) is together placed in pulverizer and pulverizes, mix homogeneously, crosses 110 mesh sieves, for subsequent use;
(4) mass concentration adding 9 times amount in above-mentioned mixing fine powders is the ethanol of 95%, sealing immersion 20 days, and jolting every day 6 times, then gets supernatant, adds the ethanol of same concentrations to prescribed volume, leaves standstill 20 hours, and filter by nonwoven gauze, fill, to obtain final product.
The using method of tincture of the present invention is: clean affected part, gets appropriate tincture of the present invention, even wiping affected part, every day three times, 10 days courses for the treatment of.
Model case a: XX, man, 43 years old, people from Qingdao.Patient is to our hospital in December in 2012 11 days.Patient's readme: the right side gonalgia 1 year, increases the weight of 5 days.Patient's pain in time starting right side gonalgia walking without obvious inducement and squat down the year before increases the weight of, once anti-inflammation analgesis medicament and acupuncture, diathermy, closed treating was taken, without obvious curative effects, and symptom increases the weight of gradually, over nearly 5 days, right side gonalgia companion swelling, activities adverse, limitation of activity come institute and seek medical advice.Check: position, side X-ray shows: joint space narrows, on patella, lower edge and condyle shape are dashed forward and are all obviously come to a point, gap calcification, and knee joint " 0 " type becomes.Be diagnosed as gonarthritis.
Use gained tincture of the present invention, using method: clean affected part, get appropriate tincture of the present invention, even wiping affected part, every day three times, 10 days courses for the treatment of.After using two courses for the treatment of, patient affected part pain obviously alleviates, and after continuing two courses for the treatment of of use, patient affected part pain disappears, and can freely bend and stretch.Patient's self-induction is fully recovered, and follow up a case by regular visits to after half a year, patient is without recurrence.
embodiment 3a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, is prepared from by following bulk drugs, is weight portion (45g/ part): Zaocys 17 parts; Rhizoma Chuanxiong 9 parts; Rhizoma Polypodiodis Nipponicae 11 parts; Radix Codonopsis 9 parts; Radix Puerariae 17 parts; Atractylodes lancea (Thunb.) DC. 10 parts; Radix Morindae Officinalis 15 parts; 17 parts, Pericarpium Citri Reticulatae Viride; Fructus Aurantii 11 parts; Rhizoma Cimicifugae 12 parts; Radix Aconiti Kusnezoffii 14 parts; Rhizoma Drynariae 14 parts; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 8.5 parts; Olibanum 13 parts; Rhizoma Sparganii 7 parts.
A kind of preparation method of arthritis dispelling wind invigorating spleen to remove dampness tincture is:
(1) get Atractylodes lancea (Thunb.) DC. sheet, pull out after soaking 28 minutes with rice-washed water, put heating in food steamer and steam thoroughly, take out dry, for subsequent use; Get Testa Tritici to be sprinkling upon in medicine of a warm nature pot, add Radix Morindae Officinalis when smoldering in pot, constantly stir-frying to powder is coke yellow, takes out, and sieve removes Testa Tritici, cools;
(2) Radix Aconiti Kusnezoffii is cleaned, is cut sheet, is placed in container, adds old Yoghourt and soaks 28 hours in 3 DEG C, and within every 30 minutes, stir once, mouth is tasted when having numb feeling in the tongue and taken out, and rinses with a small amount of water, then in 58 DEG C of forced air dryings 30 minutes, takes out, for subsequent use;
(3) will clean respectively by remaining crude drug except Atractylodes lancea (Thunb.) DC., Radix Morindae Officinalis, Radix Aconiti Kusnezoffii, and then be placed in 75 DEG C of hot-air driers dry 22 minutes, take out, then the crude drug after the process of same step (1)-(2) is together placed in pulverizer and pulverizes, mix homogeneously, crosses 70 mesh sieves, for subsequent use;
(4) mass concentration adding 6 times amount in above-mentioned mixing fine powders is the ethanol of 75%, sealing immersion 14 days, and jolting every day 3 times, then gets supernatant, adds the ethanol of same concentrations to prescribed volume, leaves standstill 13 hours, and filter by nonwoven gauze, fill, to obtain final product.
The using method of tincture of the present invention is: clean affected part, gets appropriate tincture of the present invention, even wiping affected part, every day three times, 10 days courses for the treatment of.
embodiment 4a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, is prepared from by following bulk drugs, is weight portion (35g/ part): Zaocys 18 parts; Rhizoma Chuanxiong 11 parts; Rhizoma Polypodiodis Nipponicae 13 parts; Radix Codonopsis 12 parts; Radix Puerariae 18 parts; Atractylodes lancea (Thunb.) DC. 14 parts; Radix Morindae Officinalis 20 parts; 18 parts, Pericarpium Citri Reticulatae Viride; Fructus Aurantii 13 parts; Rhizoma Cimicifugae 13 parts; Radix Aconiti Kusnezoffii 18 parts; Rhizoma Drynariae 16 parts; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 9.5 parts; Olibanum 17 parts; Rhizoma Sparganii 8 parts.
A kind of preparation method of arthritis dispelling wind invigorating spleen to remove dampness tincture is:
(1) get Atractylodes lancea (Thunb.) DC. sheet, pull out after soaking 32 minutes with rice-washed water, put heating in food steamer and steam thoroughly, take out dry, for subsequent use; Get Testa Tritici to be sprinkling upon in medicine of a warm nature pot, add Radix Morindae Officinalis when smoldering in pot, constantly stir-frying to powder is coke yellow, takes out, and sieve removes Testa Tritici, cools;
(2) Radix Aconiti Kusnezoffii is cleaned, is cut sheet, is placed in container, adds old Yoghourt and soaks 32 hours in 7 DEG C, and within every 30 minutes, stir once, mouth is tasted when having numb feeling in the tongue and taken out, and rinses with a small amount of water, then in 62 DEG C of forced air dryings 30 minutes, takes out, for subsequent use;
(3) will clean respectively by remaining crude drug except Atractylodes lancea (Thunb.) DC., Radix Morindae Officinalis, Radix Aconiti Kusnezoffii, and then be placed in 75 DEG C of hot-air driers dry 28 minutes, take out, then the crude drug after the process of same step (1)-(2) is together placed in pulverizer and pulverizes, mix homogeneously, crosses 90 mesh sieves, for subsequent use;
(4) mass concentration adding 8 times amount in above-mentioned mixing fine powders is the ethanol of 85%, sealing immersion 16 days, and jolting every day 5 times, then gets supernatant, adds the ethanol of same concentrations to prescribed volume, leaves standstill 17 hours, and filter by nonwoven gauze, fill, to obtain final product.
The using method of tincture of the present invention is: clean affected part, gets appropriate tincture of the present invention, even wiping affected part, every day three times, 10 days courses for the treatment of.
Model case: old XX, female, 55 years old, people from Henan.Patient is to our hospital on August 22nd, 2012.Patient's readme: left knee joint swelling pain is had a surplus for 1 year.In local hospital treatment, effect is undesirable, Relapse rate.Introduce my institute's treatment through friend.Check: the left knee joint swelling of patient, pain alleviated while getting warmth, meet cold pain and increase the weight of.Joint joint stuffiness, thin white fur of tongue, stringy and tense pulse.
Use gained tincture of the present invention, using method: clean affected part, get appropriate tincture of the present invention, even wiping affected part, every day three times, 10 days courses for the treatment of.After using two courses for the treatment of, patient affected part pain obviously alleviates, and swelling is disappeared gradually, and after continuing two courses for the treatment of of use, patient affected part pain and swelling disappear, and left knee joint can stretch, and can squat down, stand.Patient's self-induction is fully recovered, and follow up a case by regular visits to after half a year, patient is without recurrence.
embodiment 5a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture, is prepared from by following bulk drugs, is weight portion (40g/ part): Zaocys 17.5 parts; Rhizoma Chuanxiong 10 parts; Rhizoma Polypodiodis Nipponicae 12 parts; Radix Codonopsis 10.5 parts; Radix Puerariae 17.5 parts; Atractylodes lancea (Thunb.) DC. 12 parts; Radix Morindae Officinalis 17.5 parts; 17.5 parts, Pericarpium Citri Reticulatae Viride; Fructus Aurantii 12 parts; Rhizoma Cimicifugae 12.5 parts; Radix Aconiti Kusnezoffii 16 parts; Rhizoma Drynariae 15 parts; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 9 parts; Olibanum 15 parts; Rhizoma Sparganii 7.5 parts.
A kind of preparation method of arthritis dispelling wind invigorating spleen to remove dampness tincture is:
(1) get Atractylodes lancea (Thunb.) DC. sheet, pull out after soaking 30 minutes with rice-washed water, put heating in food steamer and steam thoroughly, take out dry, for subsequent use; Get Testa Tritici to be sprinkling upon in medicine of a warm nature pot, add Radix Morindae Officinalis when smoldering in pot, constantly stir-frying to powder is coke yellow, takes out, and sieve removes Testa Tritici, cools;
(2) Radix Aconiti Kusnezoffii is cleaned, is cut sheet, is placed in container, adds old Yoghourt and soaks 30 hours in 5 DEG C, and within every 30 minutes, stir once, mouth is tasted when having numb feeling in the tongue and taken out, and rinses with a small amount of water, then in 60 DEG C of forced air dryings 30 minutes, takes out, for subsequent use;
(3) will clean respectively by remaining crude drug except Atractylodes lancea (Thunb.) DC., Radix Morindae Officinalis, Radix Aconiti Kusnezoffii, and then be placed in 75 DEG C of hot-air driers dry 25 minutes, take out, then the crude drug after the process of same step (1)-(2) is together placed in pulverizer and pulverizes, mix homogeneously, crosses 80 mesh sieves, for subsequent use;
(4) mass concentration adding 7 times amount in above-mentioned mixing fine powders is the ethanol of 80%, sealing immersion 15 days, and jolting every day, then gets supernatant, adds the ethanol of same concentrations to prescribed volume, leaves standstill 15 hours, and filter by nonwoven gauze, fill, to obtain final product.
The using method of tincture of the present invention is: clean affected part, gets appropriate tincture of the present invention, even wiping affected part, every day three times, 10 days courses for the treatment of.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Zaocys: base is former: be the entirety of Colubridae animal Zaocys removing internal organs.Nature and flavor: Gan Xian are flat.Gui Jing: " Thunder God concocts property of medicine solution ": " enter lung, spleen two warp." function cures mainly: wind-damp dispelling, the meridian dredging.Dispelling the wind and dampness pathogens insensitive impediment, numbness of the skin, bone, tuberculosis of joint, rubella scabies, leprosy, tetanus, poliomyelitis.
Rhizoma Chuanxiong: base is former: this product is the dry rhizome of samphire Rhizoma Chuanxiong.Character: this product is irregular nodular pattern fist shape agglomerate.Surface yellowish-brown, coarse shrinkage, have the wheel of most parallel ridges to save, there is the similar round stem trace of depression on top, and downside and wheel joint have most little warty root trace.Matter is solid, not frangibility, section yellow-white or lark, and the loose grease chamber having yellowish-brown, cambium ring is wavy.Nature and flavor: pungent, temperature.Gui Jing: return liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.Curing mainly: for menoxenia. amenorrhea dysmenorrhea, mass in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache.Rheumatic arthralgia.
Rhizoma Polypodiodis Nipponicae: base is former: be the rhizome of Plants of Polypodiaceae Rhizoma Polypodiodis Nipponicae.Nature and flavor: bitter, cool.Function cures mainly: removing dampness, and heat clearing away is dispeled the wind, dredging collateral, controls that acute diseases such as cholera and sunstroke is dirty has loose bowels, dysentery, gonorrhea nebulousurine, migratory arthralgia, lumbago, acute catarrhal conjunctivitis, and skin ulcer swells.
Radix Codonopsis: base is former: the dry root that this product is Campanulaceae Radix Codonopsis, element spends Radix Codonopsis or radix codonpsis tangshen.Chemical analysis: Radix Codonopsis root is containing Saponin, Alkaloid, sucrose, glucose, inulin, starch, mucus and resin etc.Nature and flavor: sweet are flat.Gui Jing: return spleen, lung meridian.Effect: invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.Cure mainly: for deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
Radix Puerariae: base is former: this product is the dry root of legume pueraria lobata.Character: this product is rectangle sheet or the blockage of rip cutting.Crust light brown, has vertical wrinkle, coarse.Tangent plane yellow-white, texture is not obvious.Matter is tough, and fibroid is strong.Nature and flavor: sweet, pungent, cool.Gui Jing: return spleen, stomach warp.Effect: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Cure mainly: for fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Atractylodes lancea (Thunb.) DC.: base is former: be the rhizome of feverfew Atractylodes lancea (Thunb.) DC..Chemical analysis: containing volatile oil, main containing atisine chloride atractydin, β-eucalyptol, hinesol, hydroxyl atractylone etc. in oil.Nature and flavor: warm in nature, acrid in the mouth, hardship.Function cures mainly: drying damp and strengthening spleen, dispels the wind, cold expelling, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity are warded off, rheumatic arthralgia, anemofrigid cold, nyctalopia nyctalopia.
Radix Morindae Officinalis: base is former: this product is the dry root of Maguireothamnus speciosus Radix Morindae Officinalis.Nature and flavor: sweet, pungent, tepor.Gui Jing: return kidney, Liver Channel.Effect: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.Cure mainly: for impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.
Pericarpium Citri Reticulatae Viride: base is former: be the peel or the young fruit that do not become heat of multiple Fructus Citri tangerinae class such as Folium Symplocoris Caudatae profit plant tangerine produced in fujian province or Zhu's Fructus Citri tangerinae etc.Chemical analysis: various Pericarpium Citri Reticulatae Viride all containing volatile oil, and contains flavonoid glycoside etc. more.Nature and flavor: toil, tepor.Gui Jing: enter liver, gallbladder meridian.Function cures mainly: soothing the liver dispelling the stagnated QI, eliminating stagnation expectorant.Control breast side of body gastralgia, hernia, food stagnation, swelling of the breast, nodule in the breast, chronic malaria addiction block.
Fructus Aurantii: base is former: this product is the dry immature fruit of rutaceae Citrus aurantium Linn. and variety thereof.Nature and flavor: bitter, pungent, sour, temperature.Gui Jing: return spleen, stomach warp.Effect: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.Cure mainly: for the breast side of body stagnation of QI.Distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, uterine prolapse.
Rhizoma Cimicifugae: base is former: be the root stock of ranunculaceae plant Rhizoma Cimicifugae, Cimicifuga Dahurica and C.heracleifolia.Nature and flavor: sweet pungent micro-hardship are cool.Gui Jing: enter lung, spleen, stomach warp.Function cures mainly: yang invigorating, delivers, rash, removing toxic substances.Control seasonal epidemic pathogens epidemic disease, headache cold and heat, laryngalgia, aphtha, macule is not saturating; Sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women is collapsed, band, and uterus drops; Carbuncle sore tumefacting virus.
Radix Aconiti Kusnezoffii: base is former: be the tuber of ranunculaceae plant Aconitum carmichjaelii Debx. (wild species), Aconitum kusnezoffii Reichb or other multiple congeners.Chemical analysis: Aconitum carmichjaelii Debx. each several part is containing alkaloid, and wherein main is aconitine.Aconine, acetic acid and benzoic acid is generated after aconitine hydrolysis.Also containing inositol and tannin in leaf.Nature and flavor: pungent, heat, poisonous.Gui Jing: enter liver, spleen, lung meridian.Function cures mainly: search wind prevailing over dampness, and dispersing cold for relieving pain opens expectorant, detumescence.Control anemofrigid-damp arthralgia, paralysis due to windstroke, tetanus, wind syndrome of head, coldness and pain in the epigastrium, accumulation of phlegm in the hypochondrium, air parcel, cold-dysentery, sore throat, carbuncle, furuncle, scrofula.
Rhizoma Drynariae: base is former: be the rhizome of Plants of Polypodiaceae Mongolian oak Herba pteridii latiusculi, drynaria baronii Diels, Drynaria propinqua, precipice Rhizoma Zingiberis Recens, bright close net Herba pteridii latiusculi and Davalliaceae plant great Ye Rhizoma Drynariae, Rhizoma Drynariae etc.Chemical analysis: Drynaria fortunei(Kunze) J.Smith rhizome is starch-containing 16.4%, glucose 5.37%, also containing naringin.Nature and flavor: bitter, temperature.Gui Jing: enter liver, kidney channel.Function cures mainly: the kidney invigorating, invigorates blood circulation, hemostasis.Control suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus.
Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae): base is former: be the herb of Chloranthaceae plant Chloranthus henryi Hemsl or Ofthe Primulaceae Rhizoma Paridis Herba lysimachiae capillipedis, narrow leaf Herba lysimachiae capillipedis.Nature and flavor: pungent, temperature, poisonous.Function cures mainly: dispel the wind, and dehumidifying, invigorates blood circulation, dissipating blood stasis.Control cough due to wind and cold, rheumatic numbness, pain, menoxenia, traumatic consumptive injury.
Olibanum: base is former: be the gum resin of olive subject plant Boswellia carterii Birdw.Nature and flavor: arduous, temperature.Gui Jing: enter the heart, liver, spleen channel.Chemical analysis: resinous 60-70%, gummy 27-35%, volatile oil 3-8%.The main component of resin is free α, β-boswellic acid 33%, in conjunction with boswellic acid 1.5%, and olibanoresene 33%.Natural gum is calcium salt and the magnesium salt 20% of arabitic acid, bassorin 6%; In addition, still containing amaroid 0.5%.Volatile oil is faint yellow, has fragrance, and containing pinene, racemization-limonene and α, β-phellandrene, its main fragrance ingredient is not bright.Function cures mainly; Regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Rhizoma Sparganii: base is former: be the tuber of Sparganiaceae plant rhizoma scirpi or little rhizoma scirpi, spire rhizoma scirpi.Chemical analysis: little rhizoma scirpi is containing volatile oil 0.05%.Nature and flavor: toil are flat.Gui Jing: enter liver.Spleen channel.Function cures mainly: removing blood stasis, circulation of qi promoting, removing food stagnancy, pain relieving.Control lump in the abdomen, coagulation of QI-blood, trusted subordinate's pain, the lower swollen pain of the side of body, amenorrhea, postnatal blood stasis is suffered from abdominal pain, traumatic injury.Skin ulcer swells hard.
test example 1the clinical practice of a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture (embodiment 5) of gained of the present invention:
1, data and method
1.1 physical data
Choose arthritic 200 example of my institute treatment in October ,-2013 in May, 2012, the age 29-62 year, 45.5 ± 3.5 years old mean age, wherein male 87 example, women 113 example; All patients are at the age, and the aspect such as the state of an illness, the course of disease is through statistical procedures, and no significant difference (P>0.05), has comparability.
1.2 Therapeutic Method
All patients are divided into treatment group and matched group at random, and treatment group takes products obtained therefrom of the present invention, and matched group takes other medicines (as peony root total glycosides capsules, closing the conventional medication such as Zhi Ling, ibuprofen granule).Observe four courses for the treatment of of treatment altogether.
1.3 curative effect determinate standard
Cure: arthroncus, heating, pain phenomenon disappear, and joint motion freely; Effective: arthroncus, heating disappear substantially, and pain phenomenon obviously alleviates, and joint motion is normal; Effective: the phenomenons such as arthroncus, pain, heating all have and alleviate in various degree or alleviate, and joint flexion-extension motion is also improved; Invalid: Sx unchanged or comparatively before aggravation.Total effective rate=(cure number of cases+effective number of cases+effectively number of cases) ∕ total inspection case load × 100%.
1.4 therapeutic outcome
Treatment group and treatment of control group result, as shown in table 1:
Table 1: the therapeutic outcome for the treatment of group and matched group compares
Therapeutic effect: cure 62 examples (62%), effective 28 examples (28%), effective 8 examples (8%), invalid 2 examples (2%), total effective rate 98%.Successful is better than matched group.
The present invention selects 15 kinds of primary raw material medicines such as Zaocys, Rhizoma Chuanxiong, Rhizoma Polypodiodis Nipponicae, Radix Codonopsis, Radix Puerariae, Atractylodes lancea (Thunb.) DC., Radix Morindae Officinalis, Pericarpium Citri Reticulatae Viride and Fructus Aurantii to be prepared from.Fang Zhong, Rhizoma Polypodiodis Nipponicae has removing dampness, heat clearing away, dispels the wind, the function of dredging collateral; Radix Codonopsis invigorating the spleen and replenishing QI, spleen invigorating lung benefiting; Atractylodes lancea (Thunb.) DC. be used for distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity are warded off, rheumatic arthralgia, anemofrigid cold, nyctalopia nyctalopia; Radix Morindae Officinalis has kidney-replenishing, bone and muscle strengthening, effect of wind-damp dispelling; Radix Aconiti Kusnezoffii has dispelling wind and drives wet, effect of dispersing cold for relieving pain; All medicines share, altogether effect of long memorial wind invigorating spleen to remove dampness.After treating two courses for the treatment of, treatment group effective percentage can reach 98%, and matched group is only 79%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. an arthritis dispelling wind invigorating spleen to remove dampness tincture, is characterized in that, be prepared from by following bulk drugs, be weight portion: Zaocys 15-20; Rhizoma Chuanxiong 8-12; Rhizoma Polypodiodis Nipponicae 9-15; Radix Codonopsis 7-14; Radix Puerariae 15-20; Atractylodes lancea (Thunb.) DC. 8-16; Radix Morindae Officinalis 10-25; Pericarpium Citri Reticulatae Viride 15-20; Fructus Aurantii 9-15; Rhizoma Cimicifugae 10-15; Radix Aconiti Kusnezoffii 12-20; Rhizoma Drynariae 12-18; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 8-10; Olibanum 10-20; Rhizoma Sparganii 6-9.
2. a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Zaocys 17-18; Rhizoma Chuanxiong 9-11; Rhizoma Polypodiodis Nipponicae 11-13; Radix Codonopsis 9-12; Radix Puerariae 17-18; Atractylodes lancea (Thunb.) DC. 10-14; Radix Morindae Officinalis 15-20; Pericarpium Citri Reticulatae Viride 17-18; Fructus Aurantii 11-13; Rhizoma Cimicifugae 12-13; Radix Aconiti Kusnezoffii 14-18; Rhizoma Drynariae 14-16; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 8.5-9.5; Olibanum 13-17; Rhizoma Sparganii 7-8.
3. a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture as claimed in claim 1, is characterized in that, be prepared from by following bulk drugs, be weight portion: Zaocys 17.5; Rhizoma Chuanxiong 10; Rhizoma Polypodiodis Nipponicae 12; Radix Codonopsis 10.5; Radix Puerariae 17.5; Atractylodes lancea (Thunb.) DC. 12; Radix Morindae Officinalis 17.5; Pericarpium Citri Reticulatae Viride 17.5; Fructus Aurantii 12; Rhizoma Cimicifugae 12.5; Radix Aconiti Kusnezoffii 16; Rhizoma Drynariae 15; Herba Chloranthi Henryi (Herba Choranthi seu Lysimachiae) 9; Olibanum 15; Rhizoma Sparganii 7.5.
4. a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture as described in as arbitrary in claim 1-3, it is characterized in that, step is as follows:
(1) get Atractylodes lancea (Thunb.) DC. sheet, pull out (pulling out after preferably soaking 30 minutes with rice-washed water) after soaking 25-35 minute with rice-washed water, put heating in food steamer and steam thoroughly, take out dry, for subsequent use; Get Testa Tritici to be sprinkling upon in medicine of a warm nature pot, add Radix Morindae Officinalis when smoldering in pot, constantly stir-frying to powder is coke yellow, takes out, and sieve removes Testa Tritici, cools;
(2) Radix Aconiti Kusnezoffii is cleaned, is cut sheet, is placed in container, adds old Yoghourt and soaks, within every 30 minutes, stir once, mouth is tasted when having numb feeling in the tongue and is taken out, and rinses with a small amount of water, then in 55-65 DEG C of forced air drying 30 minutes (being preferable over 60 DEG C of forced air dryings 30 minutes), take out, for subsequent use;
(3) will clean respectively by remaining crude drug except Atractylodes lancea (Thunb.) DC., Radix Morindae Officinalis, Radix Aconiti Kusnezoffii, then be placed in 75 DEG C of hot-air driers dry, take out, then the crude drug after the process of same step (1)-(2) is together placed in pulverizer and pulverizes, mix homogeneously, sieves for subsequent use;
(4) in above-mentioned mixing fine powders, add the ethanol (preferably adding the ethanol of 7 times amount in above-mentioned mixing fine powders) of 5-9 times amount, sealing is soaked 10-20 days (preferably sealing immersion 15 days), jolting every day, then supernatant is got, add the ethanol of same concentrations to prescribed volume, leave standstill 10-20 hour (preferably leaving standstill 15 hours), filter by nonwoven gauze, fill, to obtain final product.
5. the preparation method of a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture according to claim 4, it is characterized in that, the time adding the immersion of old Yoghourt in step (2) is 24-36 hour (time preferably adding the immersion of old Yoghourt is 28-32 hour, and the time adding the immersion of old Yoghourt be more preferably is 30 hours).
6. the preparation method of a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture according to claim 4, it is characterized in that, the temperature adding the immersion of old Yoghourt in step (2) is 0-10 DEG C (temperature preferably adding the immersion of old Yoghourt is 3-7 DEG C, and the temperature adding the immersion of old Yoghourt be more preferably is 5 DEG C).
7. the preparation method of a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture according to claim 4, it is characterized in that, in step (3), the time of hot air drying is 18-32 minute (time of preferred hot air drying is 22-28 minute, and the time of the hot air drying be more preferably is 25 minutes).
8. the preparation method of a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture according to claim 4, is characterized in that, the middle 50-110 mesh sieve excessively of step (3) (preferred 70-90 mesh sieve excessively, mistake 80 mesh sieve be more preferably).
9. the preparation method of a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture according to claim 4, it is characterized in that, in step (4), the mass concentration of added ethanol is the mass concentration of the preferred added ethanol of 65%-95%(is 75%-85%, and the mass concentration of the added ethanol be more preferably is 80%).
10. the preparation method of a kind of arthritis dispelling wind invigorating spleen to remove dampness tincture according to claim 4, it is characterized in that, in step (4), the number of times of jolting every day is 2-6 time (number of times of preferred jolting every day is 3-5 time, and the number of times of jolting every day be more preferably is 4 times).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510051263.XA CN104524379A (en) | 2015-02-02 | 2015-02-02 | Wind-dispelling spleen-invigorating dampness-removing tincture for treating arthritis and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510051263.XA CN104524379A (en) | 2015-02-02 | 2015-02-02 | Wind-dispelling spleen-invigorating dampness-removing tincture for treating arthritis and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104524379A true CN104524379A (en) | 2015-04-22 |
Family
ID=52840135
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510051263.XA Pending CN104524379A (en) | 2015-02-02 | 2015-02-02 | Wind-dispelling spleen-invigorating dampness-removing tincture for treating arthritis and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104524379A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229334A (en) * | 2008-01-29 | 2008-07-30 | 成都芝芝药业有限公司 | Medicine for treating rheumatoid and atrophic arthritis |
| JP2011042616A (en) * | 2009-08-20 | 2011-03-03 | Tokai Univ | Joint cartilage damage therapeutic agent |
-
2015
- 2015-02-02 CN CN201510051263.XA patent/CN104524379A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101229334A (en) * | 2008-01-29 | 2008-07-30 | 成都芝芝药业有限公司 | Medicine for treating rheumatoid and atrophic arthritis |
| JP2011042616A (en) * | 2009-08-20 | 2011-03-03 | Tokai Univ | Joint cartilage damage therapeutic agent |
Non-Patent Citations (3)
| Title |
|---|
| 丛明等: ""‘软系’疗法在膝关节骨性关节炎中的应用"", 《中国疗养医学》 * |
| 张年顺: "《生活中的9000个实用名方偏方》", 31 January 2009 * |
| 梁庆伟等: "《常见病症家庭药浴疗法》", 30 November 2011 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104873947A (en) | Medicinal composition for treating dog acute upper gastrointestinal hemorrhage and preparation method thereof | |
| CN104398980A (en) | Traditional Chinese medicine preparation for treating apoplectic hemiplegia and preparation method of traditional Chinese medicine preparation | |
| CN103638475B (en) | A kind of medicinal herb spray for the treatment of nodules of the breast and preparation method thereof | |
| CN105381424A (en) | Traditional Chinese medicine for detoxifying human viscera and preparation method of traditional Chinese medicine | |
| CN105435125A (en) | Chinese herbal medicine beneficial for upper gastrointestinal cancer postoperative rehabilitation | |
| CN104042981A (en) | Medicament for treating postnatal constipation and preparation method thereof | |
| CN104324350A (en) | Traditional Chinese medicine composition for chronic colitis and preparation method of traditional Chinese medicine composition | |
| CN105749172A (en) | Medicament for treating gastric calculus and preparation thereof | |
| CN104800610A (en) | Traditional Chinese medicine preparation for treating Parkinson's disease and preparation method thereof | |
| CN104547872A (en) | Traditional Chinese medicine composition for treating epilepsy | |
| CN104587129A (en) | Traditional Chinese medicinal preparation for treating chloasma and preparation method of traditional Chinese medicinal preparation | |
| CN104771660A (en) | Chinese traditional medicine preparation for treatment of gastric cancer and preparation method thereof | |
| CN104840773A (en) | Traditional Chinese medicine composition for treating vertebral artery type cervical spondylopathy and method for preparing same | |
| CN104623532A (en) | Traditional Chinese medicine composition for treating glioma and preparation method thereof | |
| CN104547953A (en) | Traditional Chinese medicine composition for treating arthritis and preparation method thereof | |
| CN104524379A (en) | Wind-dispelling spleen-invigorating dampness-removing tincture for treating arthritis and preparation method thereof | |
| CN105770760A (en) | Preparation for treating gastric ulcer and preparation method thereof | |
| CN106256363A (en) | A kind of can effective Chinese medicine composition treating obstruction of qi in the chest and cardialgia and preparation method thereof | |
| CN106692858A (en) | Medicine for treating threatened abortion and preparation method of medicine | |
| CN106177741A (en) | A kind of pharmaceutical composition improving damp-heat constitution and a kind of medicine brick and preparation method thereof | |
| CN105943999A (en) | Pharmaceutical composition for treating wind-phlegm collateral obstruction type ischemic stroke | |
| CN105456951A (en) | Traditional Chinese medicine preparation for treating breast fibroadenoma and preparing method of traditional Chinese medicine preparation | |
| CN104225311A (en) | Neurasthenia heart and spleen tonifying medicament and preparation method | |
| CN104189491A (en) | Medicament for relieving hysterical psychological disorders and preparation method of medicament | |
| CN104873780A (en) | Traditional Chinese medicine preparation for treating dysmenorrhea |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: 561000 Guizhou city of Anshun province Xixiu District No. 10 Jianshe Road Jinsui District 3 1-501 Applicant after: Feng Bo Address before: Seven Mile Fort Road Licheng District 250000 Shandong city of Ji'nan province No. 15 Applicant before: Feng Bo |
|
| COR | Change of bibliographic data | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150422 |
|
| RJ01 | Rejection of invention patent application after publication |