CN104524079A - Chinese-western medicine composition used for treating acne, burn due to hot liquid or fire and skin ulcer - Google Patents
Chinese-western medicine composition used for treating acne, burn due to hot liquid or fire and skin ulcer Download PDFInfo
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- CN104524079A CN104524079A CN201510039202.1A CN201510039202A CN104524079A CN 104524079 A CN104524079 A CN 104524079A CN 201510039202 A CN201510039202 A CN 201510039202A CN 104524079 A CN104524079 A CN 104524079A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The invention discloses a Chinese-western medicine composition used for treating acne, burn due to hot liquid or fire and skin ulcer. The Chinese-western medicine composition used for treating the acne, burn due to hot liquid or fire and skin ulcer is characterized by being formed by mixing the following raw materials: 1000ml of chloramphenicol, 40-60ml of cortisone, 80-120ml of 75% ethyl alcohol, 4-6g of dragon blood and 1-3g of borneol. The Chinese-western medicine composition used for treating the acne, burn due to hot liquid or fire and skin ulcer has the beneficial effects that chloramphenicol is taken as a main drug and can be used for eliminating various inflammations caused by acne, the main drug is assisted by an effective medicine, namely dragon blood, with the effects of eliminating stagnant blood, relieving pain, stopping bleeding and regenerating tissue to heal wound in trauma department, the borneol with the effects of dredging joint orifices, eliminating stagnated fire, removing eye opacity, improving eyesight and relieving swelling and pain is added, a small amount of anti-inflammation and antiallergic cortisone is added as an adjuvant, and the effects of clearing heat, detoxifying, diminishing inflammation, resisting to bacteria, activating blood circulation, removing stasis, dredging collaterals and removing acnes are realized jointly; the Chinese-western medicine composition is applied to an affected part and is directly acted on a diseased region, retention type hyperkeratosis can be quickly inhibited, formation of new blockage and inflammatory skin rash is prevented, sebaceous gland liquid blocked at a sebaceous gland pipe orifice is loosened and can be easily removed; and the effect of resisting to propionibacterium acnes is also realized.
Description
Technical field
The present invention relates to a kind of Chinese and western medicinal composition, be specifically related to a kind of Chinese and western medicinal composition being used for the treatment of acne, burn due to hot liquid or fire, skin ulcer, belong to medical art.
Background technology
Acne has multiple pathogenic factors, and its pathogeny is at present also very not clear, and in the effect of endocrine factors, sebum, hair follicle, microorganism is the principal element of pathogenesis of acne.
Acne and property endocrine have close relationship, adolescence was seldom fallen ill in the past, sexual function forfeiture or the people (eunuch as emasculated in imperial palace in ancient times) of going down do not fall ill, if people's application testosterone that sexual function reduces can impel the growth of beard and the generation of acne, often acne erythra is caused by thyroliberin or corticosteroid treatment disease, women premenstrually often has acne to show effect in the moon, and pregnant acne symptom alleviates.
No matter men and women has androgen and estrogen.The organ secreted sex hormones is testis and adrenal gland male; Ovary, Placenta Hominis and adrenal gland in women.Androgen and estrogen have different ratio in men and women's body, and the change of ratio may make acne occur.The growth of sebaceous gland also increases relevant with androgen with the secretion of sebum, wherein increase activity of sebaceous gland effect with testosterone the strongest, dehydroepiandrosterone (DHEA) also participation role in progesterone and adrenal cortex, the latter may play an important role in acne in the early stage.Testosterone changes into active higher 5α-dihydrotestosterone through 5α-reductase effect in skin, stimulate sebocyte cell turnover and lipid synthesis, sebum secretion is caused to increase, produce not only dense but also many sebums, can not excrete out completely, gradually accumulate in follicular orifice, hair follicle conduit is also because of hyperkeratosis under androgenic effect simultaneously, follicular wall is plump, stop sebum excretion, the epithelial cell that follicular wall comes off increases and mixes with dense thick sebum, become cheese shape material, bolt forms acne in follicular orifice, the top be later exposed to outside follicular orifice is gradually dry, again through the Oxidation of air, melanic deposition, the pollution of dust and variable color forms blackhead.The corynebacterium acnes existed in hair follicle, Staphylococcus albus and oval pityriasis sporeformer, particularly corynebacterium acnes contains the esterase that sebum is decomposed, intrafollicular sebum is decomposed by lipase and produces more free fatty, these free fatty acids can make hair follicle and perifollicolar generation no special inflammatory reaction, after the atomic ulcer of acne wall and free fatty enter neighbouring corium, add the cell near blackhead extruding, their antimicrbial power is made to decline and easily cause inflammation by the infection of antibacterial, so there is pimple in patient, pustule, rhabdion, tuberosity and abscess.
Someone thinks that primary disease is relevant with immunity in recent years, and in the humoral immunization of its patient, Serological IgG level increases, and increases with aggravation.Corynebacterium acnes produces antibody in patient body, and circulating antibody arrives the pathogenic course that local take part in Earlier period of inflammation.
About the relation of trace element and acne.Someone proves the low utilization that may affect vitamin A of patients with acne zinc in the recent period, impels pilosebaceous keratinization, and copper is low can weaken the resistance etc. of body to bacteriological infection.In a word, patients with acne trace element zinc, copper, ferrum are low, and manganese raises can make body fat metabolism, sex hormones secretion is under some influence, and adds that skin resistance is low, may have certain relation with pathogenesis of acne.
In addition, heredity is also this pathogenetic key factor.
Except above-mentioned factor, eat Animal fat and polysaccharide food, the gastrointestinal disorders such as dyspepsia or constipation, psychentonia more, the factors such as warm can have adverse influence to acne patient, the deterioration that also can aggravate acne for oral administration of the contact of mineral oils or iodide, bromide and some other medicine.
Summary of the invention
The object of the present invention is to provide a kind of Chinese and western medicinal composition being used for the treatment of acne, burn due to hot liquid or fire, skin ulcer, this Chinese and western medicinal composition can not only prevent the formation of what inflammatory erythra of new obstruction, the sebaceous gland liquid being blocked in the sebaceous gland mouth of pipe can also be made to fluff, also there is the effect of anti-acne propionibacterium simultaneously.
In order to realize above-mentioned target, the present invention adopts following technical scheme:
Be used for the treatment of a Chinese and western medicinal composition for acne, burn due to hot liquid or fire, skin ulcer, it is characterized in that, mixed by following raw material:
The aforesaid Chinese and western medicinal composition being used for the treatment of acne, burn due to hot liquid or fire, skin ulcer, is characterized in that, is mixed by following raw material:
Chinese and western medicinal composition of the present invention, its pharmacology is according to being:
(1), chloromycetin: belonging to broad-spectrum antibacterial antibiotic, is the drug of first choice for the treatment of typhoid fever, and one of specific medicament for the treatment of anaerobic infection, secondly for the treatment of the various infectious disease caused by sensitive microbial.
(2), cortisone: adrenocortical insufficiency and hypopituitarism, also for anaphylaxis and diseases associated with inflammation, rescue critical toxic.
(3), Sanguis Draxonis: sweet in the mouth, salty, property is put down, mild toxicity.GUIXIN, Liver Channel.There is effect of dissipating blood stasis analgesic therapy, hemostasis, promoting tissue regeneration and ulcer healing.Cure mainly traumatic injury, ecchymoma due to internal injury, dysmenorrhea, postpartum stagnation stomachache, continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time and hemorrhoid.Promoting blood circulation to remove blood stasis pain relieving for oral administration: can be used for wound stasis of blood pain, bones and tendons injury pain, dysmenorrhea due to blood stasis, postpartum stagnation stomachache and all pains of blood stasis trusted subordinate.External hemostasia and promoting granulation sore: be apt to control carbuncle malignant boil, do not close up for a long time, and traumatic hemorrhage, can accelerate knot to the inflammation caused by scald and be crazy about, promote wound healing.Clot in treatment abdomen, zoopery confirms significantly shorten plasma in rabbit recalcification time.Have inhibitory action to various skin tinea, Sanguis Draxonis external, have the merit of expelling pus and promoting granulation, available skin infection of controlling is burst the card do not held back for a long time, can grind external application into powder by alone Sanguis Draxonis, also can compatibility Olibanum, Myrrha etc., as XUEJIE SAN (" Shengji Zonglu ").
(4), Borneolum Syntheticum: logical all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain.Control apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order is nebula film also, enterobiasis.Preliminary observation, to some, exedens or stomatocace has good therapeutic effect.Analgesic effect is obvious, accelerates inflammation and eliminates, and promotes that oral mucosa strips off, the healing of erosion and ulcer.Respond well to the mucosal injury caused by physical factor especially, and to the mucosal injury caused by antibacterial or other complicated factors, also can auxiliary therapeutic action be played.
Prescription is resolved:
This product extracting chloromycetin does principal agent, all kinds of inflammation that acne causes can be eliminated, be aided with the traumatology section panacea Sanguis Draxonis of dissipating blood stasis analgesic therapy, hemostasis, promoting tissue regeneration and ulcer healing, add the Borneolum Syntheticum that can lead to all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain, help with on a small quantity can antiinflammatory, antianaphylactic cortisone again, gather the effect of heat clearing away, removing toxic substances, antiinflammatory, antibacterial, blood circulation promoting and blood stasis dispelling, dredging collateral anti-acne altogether.The ethanol of 75% is a comparatively ideal solvent, and it is used for dissolving Sanguis Draxonis and Borneolum Syntheticum.
Usefulness of the present invention is:
(1), this product has heat clearing away, removing toxic substances, antiinflammatory, antibacterial, blood circulation promoting and blood stasis dispelling, the effect of dredging collateral anti-acne, affected part is embrocated, and directly acts on diseased region, anelasticity hyperkeratosis can be suppressed very soon, reach the formation preventing what inflammatory erythra of new obstruction, the sebaceous gland liquid being blocked in the sebaceous gland mouth of pipe can also be made to fluff, be easily removed; Also there is the effect of anti-acne propionibacterium simultaneously, for struvite and non-inflammatory acne, all there is good therapeutical effect.
(2), preventing from scar after application this product Acne treatment, do not stay pigment.
(3), this product to burn due to hot liquid or fire, skin ulcer also has good curative effect.
Detailed description of the invention
Below in conjunction with specific embodiment, concrete introduction is done to the present invention.
One, raw material is prepared:
| Chloromycetin | Cortisone | 75% ethanol | Sanguis Draxonis | Borneolum Syntheticum | |
| Embodiment 1 | 1000ml | 40ml | 80ml | 4g | 1.5g |
| Embodiment 2 | 1000ml | 50ml | 100ml | 5g | 2g |
| Embodiment 3 | 1000ml | 60ml | 120ml | 6g | 3g |
Two, preparation method:
First Sanguis Draxonis and Borneolum Syntheticum are dissolved in 75% ethanol, then mix homogeneously with chloromycetin and cortisone and get final product, bottling sealing is for subsequent use.
Three, usage and dosage:
Every day gets this product and embrocates affected part in right amount, every day 2-3 time, within 15 days, is a course for the treatment of.
Four, case is treated:
Use we's treatment, generally equal can onset in 1 week, 2-3 week basic controlling symptom, special case needs to coordinate endo-medicine treatment.
Case 1: Lee, man, 20 years old, on March 2nd, 2009 went to a doctor.
Patient facial region's seat skin ulcer had for more than 3 years, once used multiple method to comprise oral and medicine for external application treatment, but effect was all not remarkable.
See time medical that grain of rice size acne spreads all over buccal and frons, Face and cheek acne merges in flakes, and light red tongue, tongue is greasy in vain.Whole facial oiliness secretions is more.White and greasy fur, stringy pulse is fine and smooth.
Dialectical is Deficiency and coldness of spleen and stomach, retention of dampness in middle-JIAO, therefore varioliform exanthema is longer than buccal.
Give above-mentioned medicinal liquid after conventional treatment to be coated with outward, further consultation after 15 days, new long varioliform exanthema basic controlling, the incrustation of original varioliform exanthema major part.Continue use rear face skin lesion in January all to improve, only have loose a small amount of pigment (pox print) calm, accuse recovery from illness.
Case 2: Zhao, female, 36 years old, on November 27th, 2010 went to a doctor.
Patient started before 6 years to occur whole face acne, once in a lot of hospital admission, took heat-clearing and detoxifying herb and Western medicine, external-applied ointment are wiped outward, and slightly can control, after drug withdrawal, acne recurs immediately.
Disease is seen: yellow complexion is dark red, buccal, forehead, a large amount of acne in chin position, pimple, pustule, tuberosity, and color is dark red, exceeds skin, the tenderness touched, and pothole cicatrix is obvious; Red tongue, thin fur is few, thready and weak pulse number.
Dialectical is deficiecny of liver-YIN, overabundant liver-fire syndrome.
Method for the treatment of: clearing away liver-fire, nourishing hepatic yin.Give treatment by Chinese herbs to the ill, outer wiping said medicine, patient surprisingly finds that within nearly one week, carrying out acne does not increase, and old acne nodule deliquescing, color are thin out, continues to take medicine and outer wiping.After February, yellow skin secretly disappears thin out, and acne color turns light red, and protrude pimple, tuberosity and substantially disappear, that touches slightly exceeds skin, and patient adheres to taking medicine outer wiping March, and face is smooth, and the colour of skin turns bright in vain, follows up a case by regular visits to and does not recur for 1 year.
Case 3: Zhang, female, 24 years old, on April 15th, 2013 went to a doctor.
Private prosecution connected 2 days before March eat barbecue after, face has found several little pimple, and the outer PIYANPING that is coated with is not felt any better voluntarily, then finds that varioliform exanthema increases gradually, occurs white little pus point in varioliform exanthema.
Method for the treatment of: give merely said medicine and wipe treatment outward, after 1 week, symptom controls, and use 2 weeks continuously, varioliform exanthema is all eliminated.
Case 4: Wang, female, 33 years old, on November 27th, 2010 went to a doctor.
Previously have recurrent face erythra, once arrived Ji Jia hospital and repeatedly treat, and be diagnosed as acne, therapeutic effect is not good, constipation, 2-3 day a line, light red tongue, yellow and greasy fur.
Method for the treatment of: give Radix Saposhnikoviae Tong Sheng Tonga and subtract, the above-mentioned medicinal liquid of outer painting, effective after 1 week, within 2 weeks, control symptom, continue to use, recovery from illness after 3 weeks.
Case 5: Wang, female, 15 years old, within 2012, December was gone to a doctor on the 24th.
Patient, because of careless, breaks hot-water bottle, and scald leg, area is about hand size, and after the process of locality, affected part starts to take a turn for the better, and rear affected part is scratched and occurs infecting, and within more than 20 day, does not feel any better, and the affected part ulcer that starts to suppurate is gone to a doctor to here.
Method for the treatment of: give Chinese medicine YANGHE TANG plus-minus, outer painting said medicine, after 1 week, ulcer starts healing, improvement of all forming a scab after 3 weeks, full recovery in January.
Case 6: Lee, female, 19 years old, on April 10th, 2014 went to a doctor.
Patient student, closes on the college entrance examination daily schedule irregular, often stay up late reading, usually desire for cold drinks.Have slight acne, acne on the face wiped outward by rear ointment before, can control a part, and enter February acne and increase, face is covered with Semen Allii Tuberosi size acne.
Method for the treatment of: the simple said medicine that uses is coated with outward, and after 2 weeks, symptom controls to take a turn for the better.
In sum, this product has the effect of heat clearing away, removing toxic substances, antiinflammatory, antibacterial, blood circulation promoting and blood stasis dispelling, dredging collateral anti-acne, affected part is embrocated and can be directly acted on diseased region, anelasticity hyperkeratosis can be suppressed very soon, the formation preventing what inflammatory erythra of new obstruction can not only be reached, the sebaceous gland liquid being blocked in the sebaceous gland mouth of pipe can also be made to fluff, be easily removed.
This product also has the effect of anti-acne propionibacterium simultaneously, all has good therapeutical effect for struvite and non-inflammatory acne.
It should be noted that, above-described embodiment does not limit the present invention in any form, the technical scheme that the mode that all employings are equal to replacement or equivalent transformation obtains, and all drops in protection scope of the present invention.
Claims (2)
1. be used for the treatment of a Chinese and western medicinal composition for acne, burn due to hot liquid or fire, skin ulcer, it is characterized in that, mixed by following raw material:
2. the Chinese and western medicinal composition being used for the treatment of acne, burn due to hot liquid or fire, skin ulcer according to claim 1, is characterized in that, is mixed by following raw material:
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105560175A (en) * | 2016-02-19 | 2016-05-11 | 杨钢 | Liquid medicine for treating empyrosis and preparation method thereof |
| CN105616487A (en) * | 2016-01-28 | 2016-06-01 | 施伟仁 | Liquid medicine for removing acnes |
| CN106667850A (en) * | 2017-02-28 | 2017-05-17 | 高宝化妆品（中国）有限公司 | Traditional Chinese medicine mask liquid for removing acne and preparation method thereof |
| CN106667852A (en) * | 2017-02-28 | 2017-05-17 | 高宝化妆品（中国）有限公司 | Traditional Chinese medicine cream for removing acne and preparation method thereof |
| CN106667851A (en) * | 2017-02-28 | 2017-05-17 | 高宝化妆品（中国）有限公司 | Traditional Chinese medicine acne removal cream and preparation method thereof |
| CN106727051A (en) * | 2017-02-28 | 2017-05-31 | 高宝化妆品（中国）有限公司 | A kind of Chinese medicine anti-acne elite and preparation method thereof |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105616487A (en) * | 2016-01-28 | 2016-06-01 | 施伟仁 | Liquid medicine for removing acnes |
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| CN106667850A (en) * | 2017-02-28 | 2017-05-17 | 高宝化妆品（中国）有限公司 | Traditional Chinese medicine mask liquid for removing acne and preparation method thereof |
| CN106667852A (en) * | 2017-02-28 | 2017-05-17 | 高宝化妆品（中国）有限公司 | Traditional Chinese medicine cream for removing acne and preparation method thereof |
| CN106667851A (en) * | 2017-02-28 | 2017-05-17 | 高宝化妆品（中国）有限公司 | Traditional Chinese medicine acne removal cream and preparation method thereof |
| CN106727051A (en) * | 2017-02-28 | 2017-05-31 | 高宝化妆品（中国）有限公司 | A kind of Chinese medicine anti-acne elite and preparation method thereof |
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Application publication date: 20150422 |