CN104523842A - Mulberry leaf powder effervescent tablet and preparation method thereof - Google Patents
Mulberry leaf powder effervescent tablet and preparation method thereof Download PDFInfo
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- CN104523842A CN104523842A CN201410831125.9A CN201410831125A CN104523842A CN 104523842 A CN104523842 A CN 104523842A CN 201410831125 A CN201410831125 A CN 201410831125A CN 104523842 A CN104523842 A CN 104523842A
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- folium mori
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Abstract
The invention discloses a mulberry leaf powder effervescent tablet and a preparation method thereof. The mulberry leaf powder effervescent tablet is prepared from the following components: 700-800 parts of mulberry leaf powder, 150-300 parts of sporoderm-broken ganoderma spore powder, 100-200 parts of pseudo-ginseng powder, 10-60 parts of disintegrant, 20-40 parts of lubricant, 20-50 parts of binder, 10-30 parts of filler and 10-30 parts of condiment. The effervescent tablet is prepared by virtue of the steps of mulberry leaf powder preparation, wet granule preparation, drying and tabletting. As a result, the absorption and the utilization rate of main ingredients in the mulberry leaves by the human body can be improved, the immunity of a human body can be enhanced, and good control and auxiliary treatment effects on diseases such as diabetes, hypertension and hyperlipidemia can be achieved.
Description
Technical field
The present invention relates to effervescent tablet, particularly relate to a kind of powder of Folium Mori effervescent tablet and preparation method thereof.
Background technology
In Folium Mori, DNJ (Folium Mori alkaloid) content is very high, there is blood sugar lowering, blood pressure lowering, blood fat reducing, defying age, increase endurance, reduce lipids contents, reduce cholesterol, suppress the unique effects such as intestinal toxic bacterial reproduction and peroxide generation, current people mainly make Folium Mori tea to brew up, and utilization and the absorbance of the main composition in such Folium Mori are very low.
Summary of the invention
The object of the invention is to be to provide powder of Folium Mori effervescent tablet and preparation method thereof, solve in above-mentioned prior art problem one or more.
Powder of Folium Mori effervescent tablet of the present invention, composed of the following components:
Powder of Folium Mori 700 ~ 800 parts;
Ganoderma spore powder with cellular wall broken 150 ~ 300 parts;
Radix Notoginseng powder 100 ~ 200 parts;
Disintegrating agent 10 ~ 60 parts;
Lubricant 20 ~ 40 parts;
Binding agent 20 ~ 50 parts;
Filler 10 ~ 30 parts;
Flavoring agent 10 ~ 30 parts.
Wherein, disintegrating agent is made up of basic component and acidic components, and basic component is selected from sodium carbonate, potassium carbonate, sodium bicarbonate or potassium bicarbonate; Acidic components are selected from citric acid, malic acid or tartaric acid; The scope of the mass ratio of basic component and acidic components is 2.0 ~ 3.0.
Lubricant is selected from Polyethylene Glycol ~ 6000, DL ~ leucine, sodium benzoate, magnesium stearate, sodium stearyl fumarate or differential silica gel.
Binding agent to be concentration be 3 ~ 10% PVP (polyvinylpyrrolidone) aqueous solution or PVP alcoholic solution.
Filler selects mannitol or starch.Tablet is made to have good hardness thus.
Flavoring agent comprises spice 10 ~ 20 parts.Can improve thus tablet bubble molten after palatability.
The preparation method of powder of Folium Mori effervescent tablet of the present invention is as follows, comprises the following steps:
1. the Maturity good Ramulus Mori middle and lower part Folium Mori of mulberry or the blade of three leaves is plucked;
By the Folium Mori rinsing of harvesting, dry;
At normal atmospheric pressure, 60 ~ 80 DEG C of oven dry, oven dry degree is less than 10% to water content;
The powder of Folium Mori of oven dry is broken into 80 ~ 100 object powder of Folium Mori, for subsequent use.
2. by Ganoderma spore powder with cellular wall broken, Radix Notoginseng powder, filler, flavoring agent and step 1. in preparation powder of Folium Mori mix homogeneously make compound;
By a meromict of the half of described compound total amount and basic component, binding agent total amount, make soft material, then make alkali grain, dry 1 ~ 3h in 50 ~ 60 DEG C, water content controls below 5.0% for subsequent use;
Mixed with acidic components, remaining binding agent by remaining described compound, make soft material, then make acid particles, dry 1 ~ 3h in 50 ~ 60 DEG C, water content controls below 5.0% for subsequent use.
3. by described alkali grain, acid particles and mix lubricant 2 ~ 4 minutes, last tabletting.
Its beneficial effect is, in this formula, powder of Folium Mori and Radix Notoginseng powder have control and auxiliary therapeutic action to diseases such as diabetes, hypertension, hyperlipidemia, and Ganoderma spore powder with cellular wall broken can increase the immunity of human body.
The present invention can improve human body to the absorption of Folium Mori Main Ingredients and Appearance and utilization rate, increases the immunity of human body, has control preferably and auxiliary therapeutic action diseases such as diabetes, hypertension, hyperlipidemia.
Detailed description of the invention
Below by embodiment, the present invention is described in further detail.
Embodiment 1
Powder of Folium Mori effervescent tablet, composed of the following components:
Powder of Folium Mori 700 parts;
Ganoderma spore powder with cellular wall broken 150 parts;
Radix Notoginseng powder 100 parts;
Disintegrating agent 10 parts;
Lubricant 20 parts;
Binding agent 20 parts;
Filler 10 parts;
Flavoring agent 10 parts.
Wherein, disintegrating agent is made up of basic component and acidic components, and basic component is sodium carbonate, and in other embodiments, basic component also can be potassium carbonate, sodium bicarbonate or potassium bicarbonate; Acidic components are citric acid, and in other embodiments, acidic components also can be malic acid or tartaric acid; The mass ratio of basic component and acidic components is 2.0.
Lubricant is PEG-4000, in other embodiments, also can be DL-LEUCINE, sodium benzoate, magnesium stearate, sodium stearyl fumarate or differential silica gel.
Binding agent to be concentration be 3% PVP aqueous solution.
Filler is starch.
Flavoring agent comprises spice 10 parts, and the spice in the present embodiment is Herba Menthae.
The preparation method of powder of Folium Mori effervescent tablet of the present invention is as follows, comprises the following steps:
1. the Ramulus Mori middle and lower part Folium Mori of mulberry or the blade of three leaves is plucked;
By the Folium Mori rinsing of harvesting, dry;
At normal atmospheric pressure, 60 DEG C of oven dry, oven dry degree is less than 10% to water content;
The powder of Folium Mori of oven dry is broken into 80 object powder of Folium Mori, for subsequent use.
2. by Ganoderma spore powder with cellular wall broken, Radix Notoginseng powder, filler, flavoring agent and step 1. in preparation powder of Folium Mori mix homogeneously make compound;
By a meromict of the half of described compound total amount and basic component, binding agent total amount, make soft material, then make alkali grain, dry 1h in 50 DEG C, water content controls below 5.0% for subsequent use;
Mixed with acidic components, remaining binding agent by remaining described compound, make soft material, then make acid particles, dry 1h in 50 DEG C, water content controls below 5.0% for subsequent use.
3. by described alkali grain, acid particles and mix lubricant 2 minutes, last tabletting.
Embodiment 2
Powder of Folium Mori effervescent tablet, composed of the following components:
Powder of Folium Mori 750 parts;
Ganoderma spore powder with cellular wall broken 230 parts;
Radix Notoginseng powder 150 parts;
Disintegrating agent 35 parts;
Lubricant 30 parts;
Binding agent 35 parts;
Filler 40 parts;
Flavoring agent 40 parts.
Wherein, disintegrating agent is made up of basic component and acidic components, and basic component is potassium carbonate, and in other embodiments, basic component also can be potassium carbonate, sodium bicarbonate or potassium bicarbonate; Acidic components are malic acid, and in other embodiments, acidic components also can be malic acid or tartaric acid; The mass ratio of basic component and acidic components is 2.5.
Lubricant is PEG-4000, in other embodiments, also can be DL-LEUCINE, sodium benzoate, magnesium stearate, sodium stearyl fumarate or differential silica gel.
Binding agent to be concentration be 6% PVP alcoholic solution.
Filler is mannitol.
Flavoring agent comprises spice 15 parts, and the spice in the present embodiment is Herba Menthae.
The preparation method of powder of Folium Mori effervescent tablet of the present invention is as follows, comprises the following steps:
1. the Ramulus Mori middle and lower part Folium Mori of mulberry or the blade of three leaves is plucked;
By the Folium Mori rinsing of harvesting, dry;
At normal atmospheric pressure, 70 DEG C of oven dry, oven dry degree is less than 10% to water content;
The powder of Folium Mori of oven dry is broken into 90 object powder of Folium Mori, for subsequent use.
2. by Ganoderma spore powder with cellular wall broken, Radix Notoginseng powder, filler, flavoring agent and step 1. in preparation powder of Folium Mori mix homogeneously make compound;
By a meromict of the half of described compound total amount and basic component, binding agent total amount, make soft material, then make alkali grain, dry 2h in 55 DEG C, water content controls below 5.0% for subsequent use;
Mixed with acidic components, remaining binding agent by remaining described compound, make soft material, then make acid particles, dry 2h in 55 DEG C, water content controls below 5.0% for subsequent use.
3. by described alkali grain, acid particles and mix lubricant 3 minutes, last tabletting.
Embodiment 3
Powder of Folium Mori effervescent tablet, composed of the following components:
Powder of Folium Mori 800 parts;
Ganoderma spore powder with cellular wall broken 300 parts;
Radix Notoginseng powder 200 parts;
Disintegrating agent 60 parts;
Lubricant 40 parts;
Binding agent 50 parts;
Filler 30 parts;
Flavoring agent 30 parts.
Wherein, disintegrating agent is made up of basic component and acidic components, and basic component is sodium bicarbonate, and in other embodiments, basic component also can be potassium carbonate, sodium bicarbonate or potassium bicarbonate; Acidic components are tartaric acid, and in other embodiments, acidic components also can be malic acid or tartaric acid; The scope of the mass ratio of basic component and acidic components is 3.0.
Lubricant is PEG-4000, in other embodiments, also can be DL-LEUCINE, sodium benzoate, magnesium stearate, sodium stearyl fumarate or differential silica gel.
Binding agent to be concentration be 10% PVP aqueous solution.
Filler is starch.
Flavoring agent comprises spice 20 parts, and the spice in the present embodiment is Herba Menthae.
The preparation method of powder of Folium Mori effervescent tablet of the present invention is as follows, comprises the following steps:
1. the Ramulus Mori middle and lower part Folium Mori of mulberry or the blade of three leaves is plucked;
By the Folium Mori rinsing of harvesting, dry;
At normal atmospheric pressure, 80 DEG C of oven dry, oven dry degree is less than 10% to water content;
The powder of Folium Mori of oven dry is broken into 100 object powder of Folium Mori, for subsequent use.
2. by Ganoderma spore powder with cellular wall broken, Radix Notoginseng powder, filler, flavoring agent and step 1. in preparation powder of Folium Mori mix homogeneously make compound;
By a meromict of the half of described compound total amount and basic component, binding agent total amount, make soft material, then make alkali grain, dry 3h in 60 DEG C, water content controls below 5.0% for subsequent use;
Mixed with acidic components, remaining binding agent by remaining described compound, make soft material, then make acid particles, dry 3h in 60 DEG C, water content controls below 5.0% for subsequent use.
3. by described alkali grain, acid particles and mix lubricant 2 ~ 4 minutes, last tabletting.
The usage and dosage of product of the present invention, puts into product of the present invention after warm water is dissolved and takes, a 1g, 3 times on the one, one after each meal, to reach the object reducing blood glucose, blood pressure and blood fat.
For effect after three people use half a year of the product of the embodiment of the present invention 1 as following table:
For effect after three people use half a year of the product of the embodiment of the present invention 2 as following table:
For effect after three people use half a year of the product of the embodiment of the present invention 3 as following table:
Its beneficial effect is, in this formula, powder of Folium Mori and Radix Notoginseng powder have control and auxiliary therapeutic action to diseases such as diabetes, hypertension, hyperlipidemia, and Ganoderma spore powder with cellular wall broken can increase the immunity of human body.
In sum, the present invention can improve human body to the absorption of Folium Mori Main Ingredients and Appearance and utilization rate, increases the immunity of human body, has control preferably and auxiliary therapeutic action diseases such as diabetes, hypertension, hyperlipidemia.
The above is only one embodiment of the present invention; it should be pointed out that to those skilled in the art, without departing from the concept of the premise of the invention; can also make some similar distortion and improvement, these also should be considered as within protection scope of the present invention.
Claims (7)
1. powder of Folium Mori effervescent tablet, is characterized in that: composed of the following components:
Powder of Folium Mori 700 ~ 800 parts;
Ganoderma spore powder with cellular wall broken 150 ~ 300 parts;
Radix Notoginseng powder 100 ~ 200 parts;
Disintegrating agent 10 ~ 60 parts;
Lubricant 20 ~ 40 parts;
Binding agent 20 ~ 50 parts;
Filler 10 ~ 30 parts;
Flavoring agent 10 ~ 30 parts.
2. powder of Folium Mori effervescent tablet according to claim 1, it is characterized in that: described disintegrating agent is made up of basic component and acidic components, basic component is selected from sodium carbonate, potassium carbonate, sodium bicarbonate or potassium bicarbonate; Acidic components are selected from citric acid, malic acid or tartaric acid; The scope of the mass ratio of basic component and acidic components is 2.0 ~ 3.0.
3. powder of Folium Mori effervescent tablet according to claim 2, is characterized in that: described lubricant is selected from Polyethylene Glycol ~ 6000, DL ~ leucine, sodium benzoate, magnesium stearate, sodium stearyl fumarate or differential silica gel.
4. powder of Folium Mori effervescent tablet according to claim 2, is characterized in that: described binding agent to be concentration be 3 ~ 10% PVP aqueous solution or PVP alcoholic solution.
5. powder of Folium Mori effervescent tablet according to claim 2, is characterized in that: described filler selects mannitol or starch.
6. powder of Folium Mori effervescent tablet according to claim 2, is characterized in that: described flavoring agent comprises spice 10 ~ 20 parts.
7. the preparation method of the powder of Folium Mori effervescent tablet according to any one of claim 2 ~ 6, is characterized in that: comprise the following steps:
1. the Ramulus Mori middle and lower part Folium Mori of mulberry or the blade of three leaves is plucked;
By the Folium Mori rinsing of harvesting, dry;
At normal atmospheric pressure, 60 ~ 80 DEG C of oven dry, oven dry degree is less than 10% to water content;
The powder of Folium Mori of oven dry is broken into 80 ~ 100 object powder of Folium Mori, for subsequent use;
2. by Ganoderma spore powder with cellular wall broken, Radix Notoginseng powder, filler, flavoring agent and step 1. in preparation powder of Folium Mori mix homogeneously make compound;
By a meromict of the half of described compound total amount and basic component, binding agent total amount, make soft material, then make alkali grain, dry 1 ~ 3h in 50 ~ 60 DEG C, water content controls below 5.0% for subsequent use;
Mixed with acidic components, remaining binding agent by remaining described compound, make soft material, then make acid particles, dry 1 ~ 3h in 50 ~ 60 DEG C, water content controls below 5.0% for subsequent use;
3. by described alkali grain, acid particles and mix lubricant 2 ~ 4 minutes, last tabletting.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410831125.9A CN104523842A (en) | 2014-12-26 | 2014-12-26 | Mulberry leaf powder effervescent tablet and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410831125.9A CN104523842A (en) | 2014-12-26 | 2014-12-26 | Mulberry leaf powder effervescent tablet and preparation method thereof |
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| CN104523842A true CN104523842A (en) | 2015-04-22 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201410831125.9A Pending CN104523842A (en) | 2014-12-26 | 2014-12-26 | Mulberry leaf powder effervescent tablet and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105360872A (en) * | 2015-11-24 | 2016-03-02 | 广西壮族自治区农业科学院农产品加工研究所 | Pitaya effervescent tablets and preparation method thereof |
| CN107027925A (en) * | 2017-03-27 | 2017-08-11 | 成都大学 | Ganoderma lucidum Assorted Chinese Herbal Tea and preparation method thereof |
| CN107691959A (en) * | 2017-11-16 | 2018-02-16 | 天津市农业生物技术研究中心 | A kind of lucidum spore powder effervescent tablet and preparation method thereof |
-
2014
- 2014-12-26 CN CN201410831125.9A patent/CN104523842A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105360872A (en) * | 2015-11-24 | 2016-03-02 | 广西壮族自治区农业科学院农产品加工研究所 | Pitaya effervescent tablets and preparation method thereof |
| CN105360872B (en) * | 2015-11-24 | 2018-06-19 | 广西壮族自治区农业科学院农产品加工研究所 | A kind of dragon fruit effervescent tablet and preparation method thereof |
| CN107027925A (en) * | 2017-03-27 | 2017-08-11 | 成都大学 | Ganoderma lucidum Assorted Chinese Herbal Tea and preparation method thereof |
| CN107691959A (en) * | 2017-11-16 | 2018-02-16 | 天津市农业生物技术研究中心 | A kind of lucidum spore powder effervescent tablet and preparation method thereof |
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Application publication date: 20150422 |