CN104523826A

CN104523826A - Medicine for treating nasosinusitis

Info

Publication number: CN104523826A
Application number: CN201510032247.6A
Authority: CN
Inventors: 李海红; 耿建芳
Original assignee: Individual
Current assignee: Individual
Priority date: 2015-01-23
Filing date: 2015-01-23
Publication date: 2015-04-22

Abstract

The invention relates to a medicine for treating nasosinusitis. The medicine is prepared from the following raw materials in parts by weight: 10 parts of small centipeda herb, 9 parts of perillaseed, 6 parts of fructus xanthii and 9 parts of astragalus membranaceus. The inventor comprehends the sum and substance of ancient books and records according to the treatment experience of the traditional literature origins, researches the pathology of rhinitis by combining with the modern medicine, and summarizes the medicine to treat nasosinusitis. The small centipeda herb in the prescription is acrid in taste and mild in property, belongs to the lung channel, and has the efficacies of dispersing wind-cold, relieving stuffy nose, reliving coughing, detoxifying and relieving itching; the perillaseed belongs to the lung channel, and has the efficacies of depressing qi, dissolving phlegm, relieving cough and asthma; the fructus xanthii belongs to the lung channel and has the functions of dispersing wind, removing dampness, opening orifices and relieving pain; the astragalus membranaceus has the functions of invigorating qi and tonifying the spleen; and the nasosinusitis can be basically eliminated.

Description

A kind of medicine being used for the treatment of sinusitis

Technical field

The present invention relates to a kind of medicine, be specifically related to a kind of Chinese medicine being used for the treatment of sinusitis.

Background technology

Sinusitis, the common the main pathogenic fungi of acute sinusitis is with Haemophilus influenzae and streptococcus pneumoniae, and clinical is principal character mainly with nasal obstruction, many pus tears, headache; Chronic sinusitis is often secondary to acute purulent nasosinusitis, and main manifestations is pus tears, and simultaneously also with nasal obstruction, the symptom such as headache and olfactory disorder that weight differs, can cause hypomnesis, the situation such as absent minded, the course of disease is long, easily delays recurrence simultaneously.

Modern medicine is thought, chronic sinusitis is the inflammation of liquid and (or) hole wall sclerotin in sinus mucosa, hole.Common causative factors has infective agent, Rhino Sinus compound operation obstruction, mucociliary 26S Proteasome Structure and Function obstacle, immunologic function disorder, environmental factors and general factor.Morbidity is mostly because the hobby etc. of region and the transition of environment, the power of body constitution and diet causes.

Chinese medicine thinks that its pathogeny of sinusitis corrodes for being subject to the damp and hot pathogenic factor that waits for a long time, asthenia of pulmonosplenic qi, and respectful falling not normally causes that expectorant is turbid to be stopped gathering in nose key, the smoked nose key sarolemma that burns of pathogenic heat, and the state of an illness is touching, and prolonged illness causes the stasis of blood, phlegm and blood stasis, forms that this is sick.

Medical material involved in the present invention is all recorded in " Chinese Pharmacopoeia ".

Summary of the invention

The present invention aims to provide a kind of medicine being used for the treatment of sinusitis, by selecting suitable medical material and proportioning thereof, reaches the safe and effective object being applied to Nasosinusitis therapy.

In order to achieve the above object, the present invention is by the following technical solutions:

Be used for the treatment of a medicine for sinusitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Centipedae 10 parts, Fructus Perillae 9 parts, Fructus Xanthii 6 parts, the Radix Astragali 9 parts.

Inventor, according to the Couple herbs had the deep influence of a scholarly family, understands the main idea that ancient books and records are discussed, and in conjunction with the pathological study of modern medicine to rhinitis, sums up the present invention, in order to treat sinusitis.The effects such as in side, Herba Centipedae acrid in the mouth is warm in nature, returns lung meridian, has dispersing wind-cold, clearing the nasal passage, cough-relieving, removing toxic substances, antipruritic; Fructus Perillae as lung meridian, sending down the abnormal ascending QI expectorant, relieving cough and asthma; Fructus Xanthii, returns lung meridian, has the function of the dehumidifying of loose wind, understand things pain-stopping; The Radix Astragali, air making-up and spleen enlivening.All medicines share, and treatment sinusitis, can accomplish that As the medicine took effect, the symptoms lessened substantially.

Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:

1, object and method

Inventor collects 100 routine patients altogether during in November, 2012 in June, 2013, and patient dependence is all good, can follow up a case by regular visits to check.

1.1 include case standard in

Inclusive criteria: 1. the age 18-60 year between: 2. cardinal symptom: stream stickiness, purulence tears, nasal obstruction; Minor symptom: Head And Face distending pain, hyposmia or forfeiture, meet two or more symptom above, wherein at least has a cardinal symptom; 8. chronic sinusitis I type (not accompanying nasal polyp) diagnostic criteria (having scope and the support of CT examination result) is met; 4. Chinese medical discrimination is damp-heat accumulation type; 5. more than 3 months courses of disease are had.

Exclusion standard: 1. age <18 year or >60 year person; 2. there is the diseases such as severe cardiac, lung, liver, kidney or blood system or affect the serious disease of its life quality: 3. treating in first 1 month has nose hormone therapy history; 4. person can on request be followed up a case by regular visits to.

Rejecting standard: 1. do not treat on request; 2. treatments period adopts the other treatment mode beyond therapeutic scheme; In two, any one occurs, namely rejects case.

1.2 physical data

In 90 routine patients, man 56 example, female 44 example, at minimum 12 years old of age, maximum 65 years old, the course of disease was the shortest 3 months, the longest nearly 7 years.Be divided into treatment group and each 50 examples of matched group at random, compare physical data there was no significant difference, there is comparability for two groups.

2, research method

2.1 Therapeutic Method

Treatment group takes the capsule that the present invention obtains according to specific embodiment 3, and every bu is taken for 2 times sooner or later.

Matched group uses fluticasone propionate nasal spray spray nose, uses according to its description.

All treat 3 months for two groups.

2.2 statistical method

Adopt SPSS18.0 statistics software data processing.

3, therapeutic outcome

3.1 criterion of therapeutical effect

Cure: subjective symptoms disappears completely, sinus mucosa and the congested swelling of concha nasalis are disappeared, and nasal meatus is without secretions, and nasal sinuses CT examination is normal, follows up a case by regular visits to half a year without recurrence;

Take a turn for the better: subjective symptoms is clearly better, sinus mucosa and the congested swelling of concha nasalis are disappeared substantially, and nasal meatus is without secretions or have a small amount of glutinous purulent secretion, and nasal sinuses CT examination hole chamber is slightly fuzzy;

Invalid: symptom is unchanged or change is little, and concha nasalis and sinus mucosa be congested swelling still, still has purulence or sticky discharge in nasal meatus.

3.2 liang of group curative effects

Result treatment group cures 29 examples, and take a turn for the better 17 examples, invalid 4 examples, total effective rate 92.0%; Matched group cures 17 examples, and take a turn for the better 21 examples, and invalid 12 examples, total effective rate 76.0%, visible treatment group effective percentage is significantly better than matched group.

3.3 untoward reaction

Over the course for the treatment of, there is gastrointestinal reaction 5 example in matched group to patient, adverse reaction rate is 10%, and treatment group has no obvious adverse reaction.

Visible, the medicine that the present invention obtains can safe and effective treatment sinusitis, has good medical science promotional value.

Detailed description of the invention

In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.

Embodiment 1

Take: Herba Centipedae 10 parts, Fructus Perillae 9 parts, Fructus Xanthii 6 parts, the Radix Astragali 9 parts; Add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, is concentrated into 120 grams, must meet the decoct of adult normal's one day consumption.

Be used for the treatment of sinusitis.Oral, every bu morning, noon and afternoon take for three times.

Embodiment 2

Take: Herba Centipedae 10 parts, Fructus Perillae 9 parts, Fructus Xanthii 6 parts, the Radix Astragali 9 parts; Add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's one day consumption.

Be used for the treatment of sinusitis.Oral, daily once.

Embodiment 3

Take: Herba Centipedae 10 parts, Fructus Perillae 9 parts, Fructus Xanthii 6 parts, the Radix Astragali 9 parts; Add 6 times of water gagings, decoct 3 times, each decoction 1 hour, merges decoction liquor, concentrated, dry, incapsulates shell, must meet the capsule of adult normal's one day consumption.

Be used for the treatment of sinusitis.Oral, every bu is taken for twice sooner or later.

Claims

1. be used for the treatment of a medicine for sinusitis, it is characterized in that, it is prepared from by the raw medicinal material of following weight proportion: Herba Centipedae 10 parts, Fructus Perillae 9 parts, Fructus Xanthii 6 parts, the Radix Astragali 9 parts.