CN104522258A - Cold-brewing tea with effects of protecting liver and reducing blood pressure and reducing fat and losing weight and preparation method thereof - Google Patents

Abstract

The invention discloses cold-brewing tea with effects of protecting liver and reducing blood pressure and reducing fat and losing weight. The cold-brewing tea is characterized by comprising the following fresh raw materials in parts by weight: 20-25 parts of nicandra physaloides, 20-25 parts of folium mori, 10-13 parts of chrysanthemums, 12-15 parts of lotus leaves, 5-7 parts of lotus flowers, 5-6 parts of semen cassiae, 7-8 parts of ginkgo leaves, 2-3 parts of common mugwort, 8-12 parts of stevia leaves, 2-3 parts of perilla leaves, 1-3 parts of rosemary, 3-4 parts of burdock, 4-6 parts of bamboo leaves, 1-2 parts of cablin potchouli herb, 1-2 parts of talc, 1-2 parts of herba equiseti hiemalis and 4-6 parts of Chinese yams. The animal and clinical tests prove that the cold-brewing tea has the effects of reducing fat and losing weight and also has the health effects of protecting the liver and reducing the blood pressure. According to the long-term test, the cold-brewing tea does not have any obvious side effect.

Description

One protects the liver step-down, fat-eliminating slimming cold brew tea and preparation method thereof

Technical field

The present invention relates to field of health care food, be specifically related to one and protect the liver step-down, fat-eliminating slimming cold brew tea and preparation method thereof.

Background technology

At present, no matter in developed country or developing country, along with the change of people's living standard and increasing of doings, high lipid food and Ethanol intake amount obviously raise, the incidence of disease of the metabolic diseases such as obesity, hyperlipidemia, fatty liver, hypertension, diabetes is all in rising trend, 50% population health as existing in Britain is tending towards fat, adds one times before than 10 years; China obesity patient has 7,000 ten thousand, adds that recessive fat about has 1.5 ~ 200,000,000 people altogether, in economically developed urban children obesity rates more than 10%.

Obesity refers to the adipose tissue of overheap in body, research shows, obesity is by many factors such as gene, environmental factor, diet structure, habits and customs, especially diet nutritional surplus causes, the fat normal physiological function not only affecting whole body, can increase the incidence of disease of the diseases such as cardiovascular and cerebrovascular disease, diabetes, fatty liver, tumour, endocrinopathy simultaneously.Wherein, fatty liver further develops, and can cause liver fibrosis, even cirrhosis.

Therefore, fat-reducing is the health problem that each overweight people must pay attention to, having various ways for fat-reducing in the market, is at most also the most easily, and namely received be slimming health product, the particularly exploitation of slim tea, but how fat-reducing in the market only considers effect of fat-eliminating slimming, but does not consider the side effect to human body from physiological Mechanism, particularly long-term toxic and side effect, the side effect of slim tea mainly comprises following a few class: 1) appetite-suppressing, causes malnutrition; 2) fat absorption blocks, and causes liposoluble vitamin and mineral absorption deficiency; 3) functional disturbances of gastrointestinal tract is caused, diarrhoea; 4) HRV index rising, metabolic rate improve; 5) easily rebound.And slim tea mostly in the market is heat clothes, but the step of water boil and cooling to be spent the much time, have impact on the convenience that it is taken to a certain extent.Although there is the tea powder of cold water solubles on the market, the tea powder multicomponent that can be processed into cold brew tea is dull, and quality is lower, is not subject to liking of consumer.

Summary of the invention

For the deficiency that above-mentioned prior art exists, one is the object of the present invention is to provide to protect the liver step-down, fat-eliminating slimming cold brew tea and preparation method thereof, while animal and clinical testing have verified that it has fat-eliminating slimming function all, also there is the health care protecting the liver step-down, and prove through long term test, non-evident effect.

For achieving the above object, the technical scheme that the present invention takes is: one protects the liver step-down, fat-eliminating slimming cold brew tea, it is characterized in that, it is prepared from by the fresh feed of following weight portion: pseudoacid slurry 20-25 part, mulberry leaf 20-25 part, chrysanthemum 10-13 part, lotus leaf 12-15 part, lotus 5-7 part, cassia seed 5-6 part, ginkgo leaf 7-8 part, beach wormwood wormwood artemisia 2-3 part, stevia rebaudian leaf 8-12 part, perilla leaf 2-3 part, repeatedly fragrant 1-3 part, great burdock achene 3-4 part, leaf of bamboo 4-6 part, wrinkled giant hyssop 1-2 part, talcum 1-2 part, scouring rush 1-2 part, Chinese yam rhizome 4-6 part.

The preparation method of cold brew tea of the present invention, comprises the steps:

1) the fresh tea raw material of dosage ratio is placed in liquid nitrogen, 10 ~ 15min, make article complete freezing solid, then vacuum freeze drying is carried out, vacuum control is in 30 ~ 50Pa scope, vacuum drying temperature controls at-35 DEG C ~-30 DEG C, dry 5 ~ 10 hours, makes the water content control of tea material be less than less than 20%;

2) then the material through vacuum freeze drying is placed in negative pressure far infrared Bulking tank and carries out pressure-difference and puffing, explosion puffing drying temperature 40 ~ 50 DEG C is set, upper pressure limit-80Pa, low pressure limit-95Pa, 3 ~ 5 hours explosion puffing drying time;

3) pulverized by tea material good for explosion puffing drying, screening, makes tea bag.

Prepared by method of the present invention protects the liver step-down, fat-eliminating slimming cold brew tea, the tea rushed out is strong limpid, without being suspended thing, all proving to have fat-reducing through animal and clinical testing disappears while fat effect, also there is hepatoprotective effect, and prove that it has no side effect through toxicity test, do not rebound after drug withdrawal.

Detailed description of the invention

Below in conjunction with detailed description of the invention, the present invention is described in detail.

Embodiment 1

One protects the liver step-down, fat-eliminating slimming cold brew tea, and it is prepared from by the fresh feed of following weight portion: pseudoacid starches 20 parts, 20 parts, mulberry leaf, chrysanthemum 10 parts, 15 parts, lotus leaf, lotus 5 parts, cassia seed 5 parts, ginkgo leaf 7 parts, beach wormwood wormwood artemisia 3 parts, stevia rebaudian leaf 10 parts, perilla leaf 2 parts, repeatedly fragrant 1 part, great burdock achene 3 parts, 4 parts, the leaf of bamboo, wrinkled giant hyssop 1 part, 1 part, talcum, scouring rush 1 part, Chinese yam rhizome 4 parts.

Its preparation method is:

1) the fresh tea raw material of dosage ratio is placed in liquid nitrogen, 10min, makes article complete freezing solid, then carry out vacuum freeze drying, vacuum control is in 30Pa scope, and vacuum drying temperature controls at-35 DEG C, dry 10 hours, the water content control of tea material is made to be less than less than 20%;

2) then the material through vacuum freeze drying is placed in negative pressure far infrared Bulking tank and carries out pressure-difference and puffing, explosion puffing drying temperature 40 DEG C is set, upper pressure limit-80Pa, low pressure limit-95Pa, 5 hours explosion puffing drying time;

3) pulverized by tea material good for explosion puffing drying, screening, makes tea bag.

Embodiment 2

One protects the liver step-down, fat-eliminating slimming cold brew tea, and it is prepared from by the fresh feed of following weight portion: pseudoacid starches 25 parts, 25 parts, mulberry leaf, chrysanthemum 13 parts, 12 parts, lotus leaf, lotus 7 parts, cassia seed 6 parts, ginkgo leaf 7 parts, beach wormwood wormwood artemisia 2 parts, stevia rebaudian leaf 8 parts, perilla leaf 3 parts, repeatedly fragrant 3 parts, great burdock achene 4 parts, 6 parts, the leaf of bamboo, wrinkled giant hyssop 2 parts, 2 parts, talcum, scouring rush 2 parts, Chinese yam rhizome 6 parts.

Its preparation method is:

1) the fresh tea raw material of dosage ratio is placed in liquid nitrogen, 15min, makes article complete freezing solid, then carry out vacuum freeze drying, vacuum control is in 50Pa scope, and vacuum drying temperature controls at-30 DEG C, dry 5 hours, the water content control of tea material is made to be less than less than 20%;

2) then the material through vacuum freeze drying is placed in negative pressure far infrared Bulking tank and carries out pressure-difference and puffing, explosion puffing drying temperature 50 C is set, upper pressure limit-80Pa, low pressure limit-95Pa, 3 hours explosion puffing drying time;

3) pulverized by tea material good for explosion puffing drying, screening, makes tea bag.

Embodiment 3

One protects the liver step-down, fat-eliminating slimming cold brew tea, and it is prepared from by the fresh feed of following weight portion: pseudoacid starches 22 parts, 22 parts, mulberry leaf, chrysanthemum 12 parts, 13 parts, lotus leaf, lotus 6 parts, cassia seed 5 parts, ginkgo leaf 8 parts, beach wormwood wormwood artemisia 2 parts, stevia rebaudian leaf 12 parts, perilla leaf 2 parts, repeatedly fragrant 2 parts, great burdock achene 3 parts, 5 parts, the leaf of bamboo, wrinkled giant hyssop 1 part, 1 part, talcum, scouring rush 1 part, Chinese yam rhizome 5 parts.

Its preparation method is:

1) the fresh tea raw material of dosage ratio is placed in liquid nitrogen, 12min, makes article complete freezing solid, then carry out vacuum freeze drying, vacuum control is in 40Pa scope, and vacuum drying temperature controls at-32 DEG C, dry 6 hours, the water content control of tea material is made to be less than less than 20%;

2) then the material through vacuum freeze drying is placed in negative pressure far infrared Bulking tank and carries out pressure-difference and puffing, explosion puffing drying temperature 45 C is set, upper pressure limit-80Pa, low pressure limit-95Pa, 4 hours explosion puffing drying time;

3) pulverized by tea material good for explosion puffing drying, screening, makes tea bag.

Embodiment 4

One protects the liver step-down, fat-eliminating slimming cold brew tea, and it is prepared from by the fresh feed of following weight portion: pseudoacid starches 23 parts, 23 parts, mulberry leaf, chrysanthemum 11 parts, 13 parts, lotus leaf, lotus 6 parts, cassia seed 6 parts, ginkgo leaf 8 parts, beach wormwood wormwood artemisia 3 parts, stevia rebaudian leaf 11 parts, perilla leaf 3 parts, repeatedly fragrant 2 parts, great burdock achene 4 parts, 5 parts, the leaf of bamboo, wrinkled giant hyssop 2 parts, 2 parts, talcum, scouring rush 2 parts, Chinese yam rhizome 5 parts.

Its preparation method is:

1) the fresh tea raw material of dosage ratio is placed in liquid nitrogen, 12min, makes article complete freezing solid, then carry out vacuum freeze drying, vacuum control is in 36Pa scope, and vacuum drying temperature controls at-33 DEG C, dry 8 hours, the water content control of tea material is made to be less than less than 20%;

2) then the material through vacuum freeze drying is placed in negative pressure far infrared Bulking tank and carries out pressure-difference and puffing, explosion puffing drying temperature 46 DEG C is set, upper pressure limit-80Pa, low pressure limit-95Pa, 4 hours explosion puffing drying time;

3) pulverized by tea material good for explosion puffing drying, screening, makes tea bag.

embodiment 3 and the cold brew tea described in embodiment 4 is selected to carry out biological function and side effect evaluation:

Not specified employing is all that the tea bag 500ml normal-temperature water containing cold brew tea 20g prepared by embodiment 3 and embodiment 4 brews below, for experiment, and the liquid thick taste that the cold brew tea bag after normal-temperature water brews steeps and clarity is good.

1. zoopery-fat-eliminating slimming effect assessment:

1) foundation of nutritive obesity

Select body weight to be the male young big white mouse of SD totally 32 of 50 ~ 60g, be divided into 4 groups at random, be respectively control group, fat group, embodiment 3 groups and embodiment 4 groups, wherein control group feeds basal feed; Feed nutrient fodder for other three groups; Free diet, drinking-water, supply feed every day 2 times, feed 45d continuously.

Feed after 45 days, control group weight average is 151.32g, and the weight average of other three groups is 194.21g, and body weight is significantly higher than Normal group (P<0.05), illustrates that obese model builds.

2) instructions of taking

Embodiment 3 groups and embodiment fill with aforementioned cold brew tea electuary according to 1.5ml/100g body weight 4 groups of every days, and control group and fat group fill with the physiological saline of same volume, once a day, continuous gavage 4 weeks, free diet, drinking-water, feed basal feed, supply feed every day 2 times.

Experimental session is observed the diet situation of animal, active state and ight soil at any time and is done rare degree, except control group every rat average amount of drinking water every day about 10mL more than control group, there is no diarrhoea phenomenon, but embodiment 3 groups and embodiment 4 groups stool number of times and quantity and urine volume more than control group.

3), after last gavage, each group rat limosis 12h, claims its body weight; And measure its body long (nose is to the length of anus); Go out the IC of rat according to the formulae discovery of Lee ' s index, experimental result is as shown in table 1.

Table 1 rat body weight, body length and IC result

Group	Experiment is body weight (g) just	Body weight (g) after experiment	Experiment afterbody length (cm)	IC
					Control group	151.76±20.23	229.18±29.87	20.1±0.3	3.04±0.82
Fat group	194.56±46.05	277.25±36.28	20.8±0.8	3.13±0.95
					Embodiment 3 groups	195.19±34.98	231.65±10.56	20.4±0.2	3.01±0.79
Embodiment 4 groups	192.99±34.12	232.75±19.56	20.4±0.3	3.02±0.89

4) lipid determination

At the end of experiment, each group Rat Fast 24h, get blood through eye socket, separation of serum, adopt the content of elisa reagent colorimetric method for determining serum total cholesterol (TC) and triglycerides (TG), experimental result is as shown in table 2.

The mensuration of table 2 rat blood serum T-CHOL (TC) and triglycerides (TG)

Group	TC(mmol/L)	TG(mmol/L)
			Control group	1.59±0.23	0.56±0.21
Fat group	1.8±0.32	0.76±0.11
			Embodiment 3 groups	1.21±0.12	0.35±0.10
Embodiment 4 groups	1.39±0.15	0.41±0.09

5) mensuration of fat index and adipocyte count, size

Solution takes the rat after blood, peels off its genitals and perinephric fat, claims fat weight, calculates the fat index (g fat weight/100g body weight) of rat.From the fat separated, get a fritter adipose tissue, fix with 10% formaldehyde, cut into slices, under 400 power microscopes, count the adipocyte number (HBF) in the full visual field.And measure adipocyte size with mircrometer gauge, experimental result is as shown in table 3.

The result of table 3 rat fat index, adipocyte count and size

Group	Fat index	Adipocyte count	Adipocyte size
				Control group	1.04±0.32	37.2±11.2	75.19±14.26
Fat group	1.91±0.12	21.9±2.9	116.35±5.87
				Embodiment 3 groups	0.72±0.17	49.9±7.8	56.89±7.52
Embodiment 4 groups	0.85±0.21	48.5±8.1	58.88±6.57

2. zoopery-acute toxicity test:

Engler (Horn) method is suddenly adopted to measure.Select Kunming mouse 32, body weight (20 ± 2) g, male and female half and half, are divided into 4 groups at random, often organize 8.Fasting 16h before experiment, drinking-water is not limit, and presses 15g/kg, 30g/kg, 60g/kg, 120g/kg dosage gavage respectively, and filled with in 24h, after administration, mouse freely ingests, drinks water, Continuous Observation 7d, records symptom and the death condition of appearance at any time.

After mouse stomach gives slim tea, the symptoms such as 120g/kg dosage group all mouse appearance activity minimizing, apocleisis, in 1d dead 2, after the mouse 1d of surviving, above-mentioned symptom fades away, and movable and diet recovers normally.Other three all mouse of dosage group, to the 7th day, none was dead, its hair color, behavior, ingest, the state of mind, the situation such as stool and urine all belong to normal.At the end of experiment, each mouse is dissected, find that its liver,spleen,kidney etc. is all without macroscopic pathology.So slim tea is to chmice acute per os median lethal dose LD50>120g/kg, be far longer than the value of animal toxicology evaluation criterion (nontoxic level LD50>15g/kg), show that this product safety is nontoxic.

3. clinical trial:

The fat volunteer in experimenter Nanjing, totally 30 examples, are divided into two groups, often organize 15 examples, experimental technique is obesity group only normal diet, and everyone cold brew tea bag that daily prepared by embodiment 3 of embodiment 3 groups brews liquid 1 time, each bag, drinks after meal, drinks 6 weeks continuously.

1) body weight, body fat total amount, the percentile detection of body fat

Experiment start and at the end of each to survey once, drug withdrawal detects after half a year again, the results are shown in Table 4.

Table 4 body weight, body fat total amount, the percentile detection of body fat

2) biochemical indicator detects

Experiment start and at the end of each to survey once, the results are shown in Table 5.

Table 5 biochemical indicator detects

Claims (6)

1. protect the liver step-down, a fat-eliminating slimming cold brew tea, it is characterized in that, it is prepared from by the fresh feed of following weight portion: pseudoacid slurry 20-25 part, mulberry leaf 20-25 part, chrysanthemum 10-13 part, lotus leaf 12-15 part, lotus 5-7 part, cassia seed 5-6 part, ginkgo leaf 7-8 part, beach wormwood wormwood artemisia 2-3 part, stevia rebaudian leaf 8-12 part, perilla leaf 2-3 part, repeatedly fragrant 1-3 part, great burdock achene 3-4 part, leaf of bamboo 4-6 part, wrinkled giant hyssop 1-2 part, talcum 1-2 part, scouring rush 1-2 part, Chinese yam rhizome 4-6 part.

2. protect the liver step-down, a fat-eliminating slimming cold brew tea, it is characterized in that, it is prepared from by the fresh feed of following weight portion: pseudoacid starches 20 parts, 20 parts, mulberry leaf, chrysanthemum 10 parts, 15 parts, lotus leaf, lotus 5 parts, cassia seed 5 parts, ginkgo leaf 7 parts, beach wormwood wormwood artemisia 3 parts, stevia rebaudian leaf 10 parts, perilla leaf 2 parts, repeatedly fragrant 1 part, great burdock achene 3 parts, 4 parts, the leaf of bamboo, wrinkled giant hyssop 1 part, 1 part, talcum, scouring rush 1 part, Chinese yam rhizome 4 parts.

3. protect the liver step-down, a fat-eliminating slimming cold brew tea, it is characterized in that, it is prepared from by the fresh feed of following weight portion: pseudoacid starches 25 parts, 25 parts, mulberry leaf, chrysanthemum 13 parts, 12 parts, lotus leaf, lotus 7 parts, cassia seed 6 parts, ginkgo leaf 7 parts, beach wormwood wormwood artemisia 2 parts, stevia rebaudian leaf 8 parts, perilla leaf 3 parts, repeatedly fragrant 3 parts, great burdock achene 4 parts, 6 parts, the leaf of bamboo, wrinkled giant hyssop 2 parts, 2 parts, talcum, scouring rush 2 parts, Chinese yam rhizome 6 parts.

4. protect the liver step-down, a fat-eliminating slimming cold brew tea, it is characterized in that, it is prepared from by the fresh feed of following weight portion: pseudoacid starches 22 parts, 22 parts, mulberry leaf, chrysanthemum 12 parts, 13 parts, lotus leaf, lotus 6 parts, cassia seed 5 parts, ginkgo leaf 8 parts, beach wormwood wormwood artemisia 2 parts, stevia rebaudian leaf 12 parts, perilla leaf 2 parts, repeatedly fragrant 2 parts, great burdock achene 3 parts, 5 parts, the leaf of bamboo, wrinkled giant hyssop 1 part, 1 part, talcum, scouring rush 1 part, Chinese yam rhizome 5 parts.

5. protect the liver step-down, a fat-eliminating slimming cold brew tea, it is characterized in that, it is prepared from by the fresh feed of following weight portion: pseudoacid starches 23 parts, 23 parts, mulberry leaf, chrysanthemum 11 parts, 13 parts, lotus leaf, lotus 6 parts, cassia seed 6 parts, ginkgo leaf 8 parts, beach wormwood wormwood artemisia 3 parts, stevia rebaudian leaf 11 parts, perilla leaf 3 parts, repeatedly fragrant 2 parts, great burdock achene 4 parts, 5 parts, the leaf of bamboo, wrinkled giant hyssop 2 parts, 2 parts, talcum, scouring rush 2 parts, Chinese yam rhizome 5 parts.

6. the preparation method protecting the liver step-down, fat-eliminating slimming cold brew tea described in any one of claim 1-5, is characterized in that, comprise the steps:

1) the fresh tea raw material of dosage ratio is placed in liquid nitrogen, 10 ~ 15min, make article complete freezing solid, then vacuum freeze drying is carried out, vacuum control is in 30 ~ 50Pa scope, vacuum drying temperature controls at-35 DEG C ~-30 DEG C, dry 5 ~ 10 hours, makes the water content control of tea material be less than less than 20%;

2) then the material through vacuum freeze drying is placed in negative pressure far infrared Bulking tank and carries out pressure-difference and puffing, explosion puffing drying temperature 40 ~ 50 DEG C is set, upper pressure limit-80Pa, low pressure limit-95Pa, 3 ~ 5 hours explosion puffing drying time;

3) pulverized by tea material good for explosion puffing drying, screening, makes tea bag.