CN104510879A - Traditional Chinese medicine for treating wind-heat and blood dryness type seborrheic dermatitis - Google Patents

Traditional Chinese medicine for treating wind-heat and blood dryness type seborrheic dermatitis Download PDF

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CN104510879A
CN104510879A CN201510008725.XA CN201510008725A CN104510879A CN 104510879 A CN104510879 A CN 104510879A CN 201510008725 A CN201510008725 A CN 201510008725A CN 104510879 A CN104510879 A CN 104510879A
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潘剑崎
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/05Chlorophycota or chlorophyta (green algae), e.g. Chlorella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • AHUMAN NECESSITIES
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    • A61K36/13Coniferophyta (gymnosperms)
    • A61K36/15Pinaceae (Pine family), e.g. pine or cedar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483Gleditsia (locust)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/894Dioscoreaceae (Yam family)
    • A61K36/8945Dioscorea, e.g. yam, Chinese yam or water yam
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    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
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Abstract

The invention relates to a traditional Chinese medicine for treating wind-heat and blood dryness type seborrheic dermatitis. The traditional Chinese medicine is prepared from the following medicinal materials in parts by weight: 5 parts of tatarian aster root, 3 parts of geranium wilfordii, 1 part of siegesbeckia orientalis, 10 parts of dye yam, 8 parts of glabrous sarcandra herb, 6 parts of pagodatree pod, 3 parts of edible manna lichen, 1 part of gleditsia, 1 part of chaulmoogratree seed, 7 parts of pine nodular branch, 2 parts of shinyleaf pricklyash root, 3 parts of spirogyra, 8 parts of Coriolus Versicolor and 5 parts of vallisneria natans. The clinical experiment proves that the traditional Chinese medicine can treat the wind-heat and blood dryness type seborrheic dermatitis safely and effectively.

Description

A kind of Chinese medicine for the treatment of wind heat blood-dryness type seborrheic dermatitis
Technical field
The present invention relates to a kind of Chinese medicine, especially relate to a kind of Chinese medicine for the treatment of wind heat blood-dryness type seborrheic dermatitis.
Background technology
Seborrheic dermatitis (seborrhoeic dermatitis) refers to smegma hyperfunctioning.Show as scalp greasiness, greasy shinny, desquamation is more, more easily occur at the flourishing position of sebum, it is a kind of chronic inflammatory disease occurred on seborrhea basis, infringement is scarlet or yellowish red color patch, surface is with greasy scales or crust, often with pruritus in various degree, adult is common, is also found in neonate.
For wind heat blood-dryness type seborrheic dermatitis, it is common in many sebums, hirsutism, hyperhidrosis position in clinical manifestation.Start from scalp, during exacerbation of symptoms can to face, after ear, axillary fossa, thoracic dorsal, omphalos and the development of pubis portion.
Particularly, seborrheic dermatitis diagnostic criteria:
1. be apt to occur in the position of being rich in sebaceous gland, as the place such as scalp, face, particularly eye, oral-nasal perimeter, throat, oxter, front.The lighter is only limitted to scalp, and severe one can be spread to elsewhere by scalp.
2. skin lesion is the infringement of pale red or pale yellow red grouper lamellar squama, and range size differs, and squama such as bran shape band oiliness or thick amassing form greasy crust.Can grab and secondary infection because of strange scratch caused by itch.
3. the course of disease is long, and hair is withered soft, sparse to come off.Send out often to have in pleat position person ooze out, rotten to the corn or chap.
At present the effective medicine of generally recognized as safe is still lacked at present for wind heat blood-dryness type seborrheic dermatitis.
Involved by Chinese medicine of the present invention, the present Research of medical material is as follows:
Radix Asteris
[source] medical material Ji Yuan: be the root welding technology of feverfew Radix Asteris.
[function cures mainly] heat clearing away; Nourishing the lung to keep the adverse QI downward; Preventing phlegm from forming and stopping coughing.
[usage and dosage] takes orally: decoct soup, 4.5-10g; Or enter ball, loose.
Herba Erodii
[source] is Huai Niuer Seedling section plant Mang cattle Seedling or Herba Erodii, nepal cranesbill, Siberia geranium and Carolina Cranesbill Herb, tuber person stork grass etc. be with the herb of fruit.
[function cures mainly] dispels the wind, and invigorates blood circulation, heat-clearing and toxic substances removing.
[usage and dosage] takes orally: decoct soup, 2 ~ 5 money; Infusing drugs in wine or endure cream.
Herba Siegesbeckiae
The herb that [source] is feverfew Herba Siegesbeckiae, Herba Siegesbeckiae or siegesbeckia glabrescens Makino.
[function cures mainly] wind-damp dispelling; The meridian dredging; Poison is striven in heat clearing away.
[usage and dosage] takes orally: decoct soup, 9-12g, 30-60g in large agent; Smash juice or enter ball, loose.
Rhizoma Dioscoreae Cirrhosae
[source] Dioscoreaceae yam Rhizoma Dioscoreae Cirrhosae Dioscorea cirrhosa Lour., is used as medicine with tuber.
[function cures mainly] promoting blood circulation and hemostasis; Regulating QI to relieve pain; Heat-clearing and toxic substances removing.
[usage and dosage] takes orally: decoct soup, 3-9g; Twist juice or grind into powder.
Herba Sarcandrae
[source] is the Herb of golden chestnut orchid Herba Pileae Scriptae Sarcandra glabra (Thunb.) Nakai.
[function cures mainly] clearing away heat and cooling blood, speckle removing of invigorating blood circulation, dispelling wind and removing obstruction in the collateral.For heat in blood purpura, purpura, rheumatic arthralgia, traumatic injury.
[usage and dosage] 9 ~ 30g.
The Fructus Sophorae
[source] this product is the dry mature fruit of leguminous plant Chinese scholartree Sophora japonica L..
[function cures mainly] clearing away heat-fire, cooling blood for hemostasis.Have blood in stool for intestinal heat, hemorrhoid swell hemorrhage, and liver-heat is had a headache, dizzy conjunctival congestion.
[usage and dosage] 6 ~ 9g.
Umbillcaria esculenta
[source] is the sporophore of Qi Yi section plant Umbillcaria esculenta.
[function cures mainly] clearing away heat to stop bleeding, relieving cough and resolving phlegm.
[usage and dosage] 3 ~ 5 money
Fructus Gleditsia
[source] medical material Ji Yuan: be fruit or the sterile fruit of leguminous plant Fructus Gleditsia.
[function cures mainly] expelling phlegm for arresting cough; Have one's ideas straightened out to lead to and close; Parasite killing eliminating stagnation.
[usage and dosage] takes orally: 1-3g, enters ball more, falls apart.
Semen Hydnocarpi
[source] is the mature seed of Flacourtiaceae plant Semen Hydnocarpi.
[function cures mainly] dispeiling pathogenic wind and removing dampness; Detoxicating and killing parasites.
[usage and dosage] takes orally: decoct soup, 0.5 ~ 1 money; Or enter pill.
Lignum Pini Nodi
[source] is pinaceae plant Pinus tabuliformis, the tuberosity of the branch of Pinus massoniana Lamb or pinus yunnanensis faranch.
[function cures mainly] dispels the wind, dampness, relaxing muscles and tendons, dredging collateral.
[usage and dosage] takes orally: decoct soup, 3 ~ 5 money; Or infusing drugs in wine.
Radix Zanthoxyli
[source] this product is the dry root of rutaceae Radix Zanthoxyli Zanthoxylum nitidum (Roxb.) DC..
[function cures mainly] promoting the circulation of QI to relieve pain, blood circulation promoting and blood stasis dispelling, dispelling wind and removing obstruction in the collateral.
[usage and dosage] 5 ~ 10g.
Water is continuous
[source] algae Chlorophyta water continuous Spirogyra intorta Jao, is used as medicine with thallus.
[function cures mainly] heat-clearing and toxic substances removing; Dampness removing.Main erysipelas; Carbuncle; Dermatitis rhus; Scald; Have loose bowels
[usage and dosage] takes orally: decoct soup, 3-10g.External: appropriate, fresh goods is cleaned, and smashes deposited.
Coriolous Dersicolor (Fr.) Quel
[source] medical material Ji Yuan: be the sporophore of On Polyporaceae Corilus versicolor Quel..
[function cures mainly] invigorating spleen to remove dampness; Relieving cough and asthma; Heat-clearing and toxic substances removing; Antitumor.
[usage and dosage] takes orally: decoct soup, 15-30g.
Herba vallisneriae Spiralis
[source] is the herb of feverfew gold waist arrow.
[function cures mainly] dampness leukorrhagia stopping; Promoting flow of QI and blood.Under master tape, color is white; Prolonged lochia
[usage and dosage] takes orally: decoct soup, 6-10g.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of wind heat blood-dryness type seborrheic dermatitis, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing wind heat blood-dryness type seborrheic dermatitis.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of wind heat blood-dryness type seborrheic dermatitis, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Asteris 5 parts, Herba Erodii 3 Fen, Herba Siegesbeckiae 1 part, Rhizoma Dioscoreae Cirrhosae 10 parts, Herba Sarcandrae 8 parts, the Fructus Sophorae 6 parts, Umbillcaria esculenta 3 parts, 1 part, Fructus Gleditsia, Semen Hydnocarpi 1 part, Lignum Pini Nodi 7 parts, Radix Zanthoxyli 2 parts, continuous 3 parts of water, Coriolous Dersicolor (Fr.) Quel 8 parts, Herba vallisneriae Spiralis 5 parts.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data
Inventor collects the out-patient of 70 routine wind heat blood-dryness type seborrheic dermatitis altogether between in July ,-2014 in February, 2010, age 21-58 year, the course of disease 1-12 month.Be divided at random: treatment group 50 example, blank group 20 example.The two groups of data such as age, state of an illness there was no significant differences, have comparability.
2, diagnosis basis
With reference to " Chinese medicine disease Standardization of diagnosis and curative effect "
Primary disease is dialectical mainly to be distinguished as blood is dry or damp-heat syndrome, and because the two is different in the cause of disease and syndrome, its rule for the treatment of is different, therefore should verify and control.
For wind heat blood-dryness type seborrheic dermatitis:
Skin lesion is yellowish red color, dry desquamative macule, has a large amount of canescence pityrosporum sample squama at head, and hair is withered to come off, and red tongue tongue is few, the symptoms such as stringy and rolling pulse.
3, test method
The capsule that the oral the present invention of 3.1 treatment group obtains according to specific embodiment 1, sooner or later respectively once, 15 days courses for the treatment of.
3.2 blank group oral placebo capsules, sooner or later respectively once.15 days courses for the treatment of.
4, criterion of therapeutical effect and therapeutic outcome
4.1 criterion of therapeutical effect
With reference to the industry standard " Chinese medical disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine promulgates, for wind heat blood-dryness type seborrheic dermatitis efficacy evaluation:
Recovery from illness: clinical symptoms all disappears, deflorescence, does not itch.
Take a turn for the better: clinical symptom relief, disappear in the large portion of erythra, gargalesthesia obviously alleviates.
Invalid: clinical symptoms is without being clearly better or increasing the weight of.
Table 1 liang group comparitive study
Group n Recovery from illness Take a turn for the better Invalid Total effective rate (%) Untoward reaction example
Treatment group 50 22(44%) 21(42%) 7(14%) 86.0% 0
Blank group 20 0(0%) 4(20.0%) 16(80.0%) 20.0% 0
For proving that the present invention has good curative effect, enumerate model case as follows:
1, Zhao, female, 26 years old, IT white collar, I tells owing to being seated at office work for a long time, lack motion, have scalp greasiness, greasy shinny situation in the nearly section time, originally think that phenomenon is common and do not pay attention to, there is flakes greasy scales in a period of time scalp subsequently, particularly wash head shortly can again occur, often with pruritus in various degree, go to local hospital to go to a doctor subsequently, it is sick to be diagnosed as wind heat blood-dryness type seborrheic dermatitis, rear hospital adopts doctor trained in Western medicine routine medication one week rear poor effect, and with exacerbation of symptoms trend.After give treatment by Chinese herbs of the present invention, after taking one week, greasy scales symptom obviously reduces, and continuous with after one month, the state of an illness is clearly better, and there is no recurrence so far.
2, Cai, female, 31 years old, JIUYUE in 2013 first visit on the 18th.Its main suit: in the recent period scalp its itch incomparably, scalp surface be cerise shape, and surperficial have a large amount of canescence pityrosporum sample squama, and during sleeping at night, head pruritus symptom is more obvious, has had a strong impact on rest in night, life, work etc.Go to local hospital to diagnose subsequently in time, be diagnosed as wind heat blood-dryness type seborrheic dermatitis disease subsequently, hospital adopts western medical treatment immediately, loses symptom take a turn for the better to some extent through treatment in 4 days.After give treatment by Chinese herbs of the present invention, after taking 3 days, scalp surface color progressively recovers normal, and squama situation obviously reduces, and after continuing to take one month, state of an illness rehabilitation is complete, and so far without recurring.
3, Tang, man, 28 years old, is engaged in agriculture.Head pruritus is serious, and hair is withered softly, sparse to come off, and scalp is aglow, and be mingled with a large amount of canescence pityrosporum sample squama between hair, morning, WA medicated pillow had a large amount of squama or crust, had a strong impact on sleep quality.Go to local institute of traditional Chinese medicine subsequently, diagnosis skin lesion is red, dry desquamative macule, a large amount of canescence pityrosporum sample squama is had at head, hair is withered to come off, red tongue tongue is few, stringy and rolling pulse etc., after be diagnosed as it by tcm syndrome classification and belong to wind heat blood-dryness type seborrheic dermatitis, adopt traditional Chinese medical science conventional therapy after hospital, after one week, symptom is not felt any better.Give treatment by Chinese herbs of the present invention subsequently, after taking one week, make coherence check and be all tending towards normalization, canescence pityrosporum sample squama symptom obviously alleviates, and takes so far always, and the reaction of patient's each side is good, there is no recurrence, and normally can work, lives.
Visible, the present invention adopts the formula of science and suitable proportioning, cooperatively interacts between each medicine, synergism, and adopt the principle for the treatment of of heat-clearing and toxic substances removing, cooling blood, expelling wind, made Chinese medicine can safe and effective treatment wind heat blood-dryness type seborrheic dermatitis.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take: Radix Asteris 5 grams, Herba Erodii 3 Ke, Herba Siegesbeckiae 1 gram, Rhizoma Dioscoreae Cirrhosae 10 grams, Herba Sarcandrae 8 grams, the Fructus Sophorae 6 grams, Umbillcaria esculenta 3 grams, 1 gram, Fructus Gleditsia, Semen Hydnocarpi 1 gram, Lignum Pini Nodi 7 grams, Radix Zanthoxyli 2 grams, continuous 3 grams of water, Coriolous Dersicolor (Fr.) Quel 8 grams, Herba vallisneriae Spiralis 5 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of wind heat blood-dryness type seborrheic dermatitis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take: Radix Asteris 5 grams, Herba Erodii 3 Ke, Herba Siegesbeckiae 1 gram, Rhizoma Dioscoreae Cirrhosae 10 grams, Herba Sarcandrae 8 grams, the Fructus Sophorae 6 grams, Umbillcaria esculenta 3 grams, 1 gram, Fructus Gleditsia, Semen Hydnocarpi 1 gram, Lignum Pini Nodi 7 grams, Radix Zanthoxyli 2 grams, continuous 3 grams of water, Coriolous Dersicolor (Fr.) Quel 8 grams, Herba vallisneriae Spiralis 5 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, pulverize, the powder of adult normal's 1 day consumption must be met.
Be used for the treatment of wind heat blood-dryness type seborrheic dermatitis.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take: Radix Asteris 5 grams, Herba Erodii 3 Ke, Herba Siegesbeckiae 1 gram, Rhizoma Dioscoreae Cirrhosae 10 grams, Herba Sarcandrae 8 grams, the Fructus Sophorae 6 grams, Umbillcaria esculenta 3 grams, 1 gram, Fructus Gleditsia, Semen Hydnocarpi 1 gram, Lignum Pini Nodi 7 grams, Radix Zanthoxyli 2 grams, continuous 3 grams of water, Coriolous Dersicolor (Fr.) Quel 8 grams, Herba vallisneriae Spiralis 5 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then add appropriate dextrin and correctives, granulate according to this area common process, packaging, can obtain the granule meeting adult normal's 1 day consumption.
Be used for the treatment of wind heat blood-dryness type seborrheic dermatitis.Oral, every bu is taken for twice sooner or later.

Claims (1)

1. treat the Chinese medicine of wind heat blood-dryness type seborrheic dermatitis for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Asteris 5 parts, Herba Erodii 3 Fen, Herba Siegesbeckiae 1 part, Rhizoma Dioscoreae Cirrhosae 10 parts, Herba Sarcandrae 8 parts, the Fructus Sophorae 6 parts, Umbillcaria esculenta 3 parts, 1 part, Fructus Gleditsia, Semen Hydnocarpi 1 part, Lignum Pini Nodi 7 parts, Radix Zanthoxyli 2 parts, continuous 3 parts of water, Coriolous Dersicolor (Fr.) Quel 8 parts, Herba vallisneriae Spiralis 5 parts.
CN201510008725.XA 2015-01-08 2015-01-08 Traditional Chinese medicine for treating wind-heat and blood dryness type seborrheic dermatitis Pending CN104510879A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103751462A (en) * 2014-02-08 2014-04-30 刘方荣 Traditional Chinese medicine tincture for treating wind-heat and blood dryness type steatorrhea dermatitis
CN103784627A (en) * 2014-02-08 2014-05-14 武风玉 Chinese medicinal composition for treating seborrheic dermatitis due to pathogenic wind-heat and blood-dryness

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103751462A (en) * 2014-02-08 2014-04-30 刘方荣 Traditional Chinese medicine tincture for treating wind-heat and blood dryness type steatorrhea dermatitis
CN103784627A (en) * 2014-02-08 2014-05-14 武风玉 Chinese medicinal composition for treating seborrheic dermatitis due to pathogenic wind-heat and blood-dryness

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
周宝宽: "脂溢性皮炎辨证论治经验", 《辽宁中医药大学学报》 *
许鹏光 等: "《中西医临床皮肤性病学》", 31 July 2012 *

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