CN104507948B - 含氮杂环n‑氧化物化合物的制造方法 - Google Patents

含氮杂环n‑氧化物化合物的制造方法 Download PDF

Info

Publication number
CN104507948B
CN104507948B CN201380040269.6A CN201380040269A CN104507948B CN 104507948 B CN104507948 B CN 104507948B CN 201380040269 A CN201380040269 A CN 201380040269A CN 104507948 B CN104507948 B CN 104507948B
Authority
CN
China
Prior art keywords
persulfate
reaction
production method
quinoline
potassium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201380040269.6A
Other languages
English (en)
Chinese (zh)
Other versions
CN104507948A (zh
Inventor
吉野弘展
关健
关健一
橘山浩英
日高生允
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Original Assignee
Nissan Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp filed Critical Nissan Chemical Corp
Publication of CN104507948A publication Critical patent/CN104507948A/zh
Application granted granted Critical
Publication of CN104507948B publication Critical patent/CN104507948B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
CN201380040269.6A 2012-09-27 2013-09-13 含氮杂环n‑氧化物化合物的制造方法 Expired - Fee Related CN104507948B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012-215045 2012-09-27
JP2012215045 2012-09-27
PCT/JP2013/074867 WO2014050613A1 (ja) 2012-09-27 2013-09-13 含窒素複素環ｎ－オキシド化合物の製造方法

Publications (2)

Publication Number Publication Date
CN104507948A CN104507948A (zh) 2015-04-08
CN104507948B true CN104507948B (zh) 2017-05-03

Family

ID=50388020

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380040269.6A Expired - Fee Related CN104507948B (zh) 2012-09-27 2013-09-13 含氮杂环n‑氧化物化合物的制造方法

Country Status (5)

Country Link
US (1) US9738654B2 (enExample)
JP (1) JP6202280B2 (enExample)
CN (1) CN104507948B (enExample)
IN (1) IN2015DN03010A (enExample)
WO (1) WO2014050613A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2015DN03012A (enExample) * 2012-09-27 2015-10-02 Nissan Chemical Ind Ltd
JP7468869B2 (ja) 2018-12-28 2024-04-16 国立大学法人大阪大学 遺伝性徐脈性不整脈治療薬
US20230241053A1 (en) 2020-06-26 2023-08-03 Osaka University Therapeutic agent for drug-induced bradycardia and bradyarrhythmia

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005255560A (ja) * 2004-03-09 2005-09-22 National Institute Of Advanced Industrial & Technology ピリジン−ｎ−オキシド類の製造方法
WO2006048425A1 (en) * 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for making a non-nucleoside hiv-1 reverse transcriptase inhibitor
CN1934116A (zh) * 2004-03-23 2007-03-21 日产化学工业株式会社 用作抗心律失常剂的三环苯并吡喃化合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN2015DN03012A (enExample) * 2012-09-27 2015-10-02 Nissan Chemical Ind Ltd

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005255560A (ja) * 2004-03-09 2005-09-22 National Institute Of Advanced Industrial & Technology ピリジン−ｎ−オキシド類の製造方法
CN1934116A (zh) * 2004-03-23 2007-03-21 日产化学工业株式会社 用作抗心律失常剂的三环苯并吡喃化合物
WO2006048425A1 (en) * 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Process for making a non-nucleoside hiv-1 reverse transcriptase inhibitor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Synthesis and Antibacterial Activity of Novel 4-Pyrrolidinylthio Carbapenems PartIV.2-Alkyl Substituents Containing Cationic Heteroaromatics Linked Via a C-C Bond;Hidenori Azami,et al.,;《Bioorganic & Medicinal Chemistry》;20011231;第9卷;第961-982页 *

Also Published As

Publication number Publication date
US9738654B2 (en) 2017-08-22
US20150266887A1 (en) 2015-09-24
CN104507948A (zh) 2015-04-08
JP6202280B2 (ja) 2017-09-27
JPWO2014050613A1 (ja) 2016-08-22
WO2014050613A1 (ja) 2014-04-03
IN2015DN03010A (enExample) 2015-10-02

Similar Documents

Publication Publication Date Title
JP4170986B2 (ja) フェニルマロン酸ジニトリルの調製方法
US8962850B2 (en) Nitrogen-containing heterocyclic compound and method for producing same
CN105263893A (zh) 环己烯酮组成物及其制备方法
CN104507948B (zh) 含氮杂环n‑氧化物化合物的制造方法
US10618868B2 (en) Method for preparing 2-aryl malonamide and applications thereof
JP6611735B2 (ja) 空気酸化による３−メチル−２−ニトロ安息香酸の調製プロセス
US9464095B2 (en) Production method of high-purity nitrogen-containing heterocyclic compound
ITMI20111455A1 (it) Nuovo procedimento per la preparazione di 1-(6-metilpiridin-3-il)-2-[4-(metilsolfonil)fenil]etanone, un intermedio dell'etoricoxib.
US20200377456A1 (en) Process for the preparation of glycopyrrolate tosylate
CN112119063B (zh) 3-二氟甲基吡唑化合物的制造方法及3-二氟甲基吡唑-4-羧酸化合物的制造方法以及吡唑烷化合物
US10112901B2 (en) Method for preparing dabigatran etexilate intermediate, and intermediate compound
EP2963026B1 (en) Substituted (r)-3-(4-methylcarbamoyl-3-fluorophenylamino)tetrahydrofuran-3-enecarboxylic acid (variants) and ester thereof, method for producing and using same
JPWO2006048935A1 (ja) ２，２’−ビス（トリフルオロメチル）−４，４’−ジアミノビフェニルの製造方法
Heravi et al. Regioselective synthesis of quinolone antibacterials via borate complex of quinolone carboxylic acid
TWI545120B (zh) ３，４－二氫異喹啉衍生物之製造方法及此等衍生物之製造中間體
WO2015199007A1 (ja) ３－（アルキルスルホニル）ピリジン－２－カルボン酸の製造方法
Reddy et al. Process related and degradation impurities in anti-inflammatory drug Roflumilast
JP2014005224A (ja) 芳香族ジアルデヒド化合物及びオリゴビニレンフェニレン化合物の製造方法
JPWO2018212162A1 (ja) ジアミノベンゼン化合物の製造方法
JPWO2008026527A1 (ja) ３−シアノピロリジン誘導体およびその塩の製造方法
JP2013100279A (ja) マンデル酸アミド誘導体の製造方法及びその中間体
JPWO2012033091A1 (ja) 安息香酸エステル類の製造法
JP2010195748A (ja) ビス（３−ニトロ−４−ヒドロキシフェニル）類の製造方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20170503

Termination date: 20190913

CF01 Termination of patent right due to non-payment of annual fee