CN104491725A - Traditional Chinese medicine preparation for treating fatty liver and hyperlipemia - Google Patents
Traditional Chinese medicine preparation for treating fatty liver and hyperlipemia Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/424—Gynostemma
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A61K36/482—Cassia, e.g. golden shower tree
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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Abstract
The invention provides a traditional Chinese medicine preparation for treating fatty liver and hyperlipemia. The raw materials of the traditional Chinese medicine preparation comprise the following traditional Chinese medicine components: curcuma zedoary, red peony roots, hawthorn, gynostemma pentaphylla, cassia occidentalis, polygonum cuspidatum, turmeric, astragalus membranaceus and wolfberries. The invention provides the traditional Chinese medicine preparation for treating fatty liver and hyperlipemia, can be used for effectively treating fatty liver and hyperlipemia and is low in price.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation being used for the treatment of fatty liver and hyperlipemia.
Background technology
Fatty liver is one disease comparatively common in modern diseases.This sick incidence rate can reach about 50%, and focuses mostly in the male of 30 ~ 60 years old.Mild fatty liver is many without clinical symptoms.In, severe fatty liver has the performance of similar chronic hepatitis, can have inappetence, lassitude and weak, Nausea and vomiting, hepatic region or upper right abdomen dull pain, if can not get effective treatment finally can cause liver cirrhosis etc.Up to the present, Western medicine there is no lipotropic active drug; Hyperlipidemia is a kind of affluenza of puzzlement modern, and it can strengthen the viscosity of blood, and harm blood circulation forms sclerosis of blood vessels.Hyperlipidemia can cause coronary heart disease, hypertension.Finally cause diabetes, sudden death heart disease, apoplexy etc.Though there is the medicine of some therapist aspects, effect is still very undesirable, and has side effect in various degree, brings larger misery to patient, and cost is higher.
Summary of the invention
The object of the invention is to the defect solving the existence of above-mentioned prior art, provide a kind of result of use good, the Chinese medicine preparation of lower-cost treatment fatty liver and hyperlipemia.
Be used for the treatment of a Chinese medicine preparation for fatty liver and hyperlipemia, its raw material comprises following Chinese medicine component: Rhizoma Curcumae, Radix Paeoniae Rubra, Fructus Crataegi, Herb Gynostemmae Pentaphylli, Semen Cassiae, Rhizoma Polygoni Cuspidati, Rhizoma Curcumae Longae, the Radix Astragali, Fructus Lycii.
Further, be used for the treatment of the Chinese medicine preparation of fatty liver and hyperlipemia as above, its raw material comprises the Chinese medicinal components of following mass parts: Rhizoma Curcumae 15 parts-75 parts, Radix Paeoniae Rubra 12 parts-60 parts, Fructus Crataegi 12 parts-60 parts, Herb Gynostemmae Pentaphylli 12 parts-60 parts, Semen Cassiae 12 parts-60 parts, Rhizoma Polygoni Cuspidati 15 parts-75 parts, 12 parts-60 parts, Rhizoma Curcumae Longae, the Radix Astragali 15 parts-75 parts, Fructus Lycii 15 parts-75 parts.
Further, be used for the treatment of the Chinese medicine preparation of fatty liver and hyperlipemia as above, its raw material comprises the Chinese medicinal components of following mass parts: Rhizoma Curcumae 15 parts, Radix Paeoniae Rubra 12 parts, Fructus Crataegi 12 parts, Herb Gynostemmae Pentaphylli 12 parts, Semen Cassiae 12 parts, Rhizoma Polygoni Cuspidati 15 parts, 12 parts, Rhizoma Curcumae Longae, the Radix Astragali 15 parts, Fructus Lycii 15 parts.
Further, be used for the treatment of the Chinese medicine preparation of fatty liver and hyperlipemia as above, its raw material comprises the Chinese medicinal components of following mass parts: choose Rhizoma Curcumae 30 parts, Radix Paeoniae Rubra 24 parts, Fructus Crataegi 24 parts, Herb Gynostemmae Pentaphylli 24 parts, Semen Cassiae 24 parts, Rhizoma Polygoni Cuspidati 30 parts, 24 parts, Rhizoma Curcumae Longae, the Radix Astragali 30 parts, Fructus Lycii 30 parts.
Further, be used for the treatment of the Chinese medicine preparation of fatty liver and hyperlipemia as above, its raw material comprises the Chinese medicinal components of following mass parts: choose Rhizoma Curcumae 75 parts, Radix Paeoniae Rubra 60 parts, Fructus Crataegi 60 parts, Herb Gynostemmae Pentaphylli 60 parts, Semen Cassiae 60 parts, Rhizoma Polygoni Cuspidati 75 parts, 60 parts, Rhizoma Curcumae Longae, the Radix Astragali 75 parts, Fructus Lycii 75 parts.
The Chinese medicine preparation being used for the treatment of fatty liver and hyperlipemia provided by the invention, can effectively treat fatty liver and hyperlipemia, and low price.
Detailed description of the invention
For making the object, technical solutions and advantages of the present invention clearly, below technical scheme in the present invention be clearly and completely described, obviously, described embodiment is the present invention's part embodiment, instead of whole embodiments.Based on the embodiment in the present invention, those of ordinary skill in the art, not making the every other embodiment obtained under creative work prerequisite, belong to the scope of protection of the invention.
The Chinese medicine preparation preparation method for the treatment of fatty liver of the present invention and hyperlipemia is as follows: (1) chooses Rhizoma Curcumae 15 parts-75 parts, Radix Paeoniae Rubra 12 parts-60 parts, Fructus Crataegi 12 parts-60 parts, Herb Gynostemmae Pentaphylli 12 parts-60 parts, Semen Cassiae 12 parts-60 parts, Rhizoma Polygoni Cuspidati 15 parts-75 parts, 12 parts-60 parts, Rhizoma Curcumae Longae, the Radix Astragali 15 parts-75 parts, Fructus Lycii 15 parts-75 parts, (2) the gross mass 6-8 water doubly getting the above nine taste Chinese medicines chosen decocts, decoct three times, boil 40-50 minute at every turn, filter and merge decoction liquor, decoction liquor is concentrated into the concentrated juice that relative density is 1.15-1.30 (80 DEG C), add the ethanol that mass percent concentration is 95% more at ambient temperature, limit edged stirs, the addition of described ethanol is 1.2-2 times of the gross mass of concentrated juice, then place more than 24 hours, extract supernatant, ethanol in supernatant is reclaimed, give in the supernatant having reclaimed ethanol and add sweeting agent, the pH value regulating solution is 5.0-7.0, finally add water and fully to mix with supernatant, stir evenly standing, through filtering, sterilizing, fill can complete preparation.
Embodiment one:
(1) Rhizoma Curcumae 150 grams is chosen, Radix Paeoniae Rubra 120 grams, Fructus Crataegi 120 grams, Herb Gynostemmae Pentaphylli 120 grams, Semen Cassiae 120 grams, Rhizoma Polygoni Cuspidati 150 grams, 120 grams, Rhizoma Curcumae Longae, the Radix Astragali 150 grams, Fructus Lycii 150 grams, (2) water getting the gross mass 6 times of the above nine taste Chinese medicines chosen again decocts, decoct three times, boil 40 minutes at every turn, filter and merge decoction liquor, be concentrated into the concentrated juice of relative density 1.15 (80 DEG C), the mass percent concentration adding concentrated juice gross mass 1.2 times is more at ambient temperature the ethanol of 95%, limit edged stirs, then place more than 24 hours, extract supernatant, ethanol in supernatant is reclaimed, give in the supernatant having reclaimed ethanol again and add suitable sweeting agent, the pH value regulating solution is 5.0, finally add water and make solution reach 10000ml, stir evenly standing, through filtering, sterilizing, fill can complete preparation.
Embodiment two:
(1) Rhizoma Curcumae 300 grams is chosen, Radix Paeoniae Rubra 240 grams, Fructus Crataegi 240 grams, Herb Gynostemmae Pentaphylli 240 grams, Semen Cassiae 240 grams, Rhizoma Polygoni Cuspidati 300 grams, 240 grams, Rhizoma Curcumae Longae, the Radix Astragali 300 grams, Fructus Lycii 300 grams, (2) water getting gross mass 7.2 times of weight of the above nine taste Chinese medicines chosen again decocts, decoct three times, boil 50 minutes at every turn, filter and merge decoction liquor, be concentrated into the concentrated juice of relative density 1.25 (80 DEG C), the gross mass adding concentrated juice is more at ambient temperature the mass percent concentration of 1.6 times is the ethanol of 95%, limit edged stirs, then place more than 24 hours, extract supernatant, the ethanol contained in supernatant is reclaimed, give in the supernatant having reclaimed ethanol again and add suitable sweeting agent, the pH value regulating solution is 6.0, finally add water and make solution reach 10000ml, stir evenly standing, through filtering, sterilizing, fill can complete preparation.
Embodiment three:
(1) Rhizoma Curcumae 750 grams is chosen, Radix Paeoniae Rubra 600 grams, Fructus Crataegi 600 grams, Herb Gynostemmae Pentaphylli 600 grams, Semen Cassiae 600 grams, Rhizoma Polygoni Cuspidati 750 grams, 600 grams, Rhizoma Curcumae Longae, the Radix Astragali 750 grams, Fructus Lycii 750 grams, (2) water getting the gross mass 8 times of the above nine taste Chinese medicines chosen again decocts, decoct three times, boil 45 minutes at every turn, filter and merge decoction liquor, be concentrated into the concentrated juice of relative density 1.30 (80 DEG C), the gross mass adding concentrated juice is more at ambient temperature the mass percent concentration of 2 times is the ethanol of 95%, limit edged stirs, then place more than 24 hours, extract supernatant, the ethanol contained in supernatant is reclaimed, give in the supernatant having reclaimed ethanol again and add suitable sweeting agent, the pH value regulating solution is 7.0, finally add water and make solution reach 10000ml, stir evenly standing, through filtering, sterilizing, fill can complete preparation.
Model case:
Name: so-and-so sex tall: female's age: 61 years old address: Xinxiang Ma little Ying
Patient occurs that aphasia, left upper extremity are unable and is admitted to hospital, with dizziness, cardiopalmus, poor appetite.Human health screening, blood pressure 170/100mmhg, sanity, aphasia, LC face tongue paralysis, white and greasy fur, Cervical Vessels is not heard and exception.Muscular strength 4 grades under upper left, hypomyotonia, left side pathology levies the positive.Head CT shows multiple infarct, and blood fat shows T-CHOL 7.28mol/L, triglyceride 2.19mol/L, HDL-C 1.22mol/L, low density cholesterol 4.70mol/L.Enter section's diagnosis: multiple infarct, hyperlipemia.After entering section, routine is given to thromboembolism preventing, is improved the symptomatic treatments such as brain blood circulation, add simultaneously and use oral liquid of the present invention 20ml/ time, every day 3 times is oral, within 20 days, checks blood fat afterwards and shows 3.87mol/L, triglyceride 1.5mol/L, HDL-C 1.92mol/L, low density cholesterol 2.28mol/L, obviously improves when being comparatively admitted to hospital, evident in efficacy, advise low fat diet at ordinary times, continue oral maintaining treatment.
Name: Yang's sex: man's age: 58 years old address: Xin electricity community, Xinxiang
Patient occurs that burst is dizzy, and left side myasthenia of limbs is admitted to hospital, with dizziness, cardiopalmus, poor appetite, and the sick official of existing coronary heart disease, atrial fibrillation.Human health screening, blood pressure 150/90mmhg, sanity, spirit is poor, and speech is fluent, and body of the tongue is slightly dark, white and greasy fur, and Cervical Vessels is not heard and exception.Muscular strength 5 grades under upper left, hypomyotonia, left side pathology levies the positive.Head MRL shows multiple infarct, and blood fat shows T-CHOL 6.15mol/L, triglyceride 2.95mol/L, HDL-C 0.75mol/L, low density cholesterol 4.36mol/L.Enter section's diagnosis: cerebral infarction, hyperlipemia.After entering section, routine is given to thromboembolism preventing, is improved the symptomatic treatments such as brain blood circulation, add simultaneously and use oral liquid of the present invention 20ml/ time, every day 3 times is oral, within 20 days, checks blood fat afterwards and shows 3.51mol/L, triglyceride 0.58mol/L, HDL-C 2.12mol/L, low density cholesterol 1.78mol/L, obviously improves when being comparatively admitted to hospital, evident in efficacy, advise low fat diet at ordinary times, continue oral maintaining treatment.
Name: the Meng so-and-so sex: female's age: 60 years old address: Xinxiang West Platform head
There is left limb hemiplegia 2 weeks in patient, abdominal distention, poor appetite are admitted to hospital for 10 days, previously obesity, 10 years hypertension officials, human health screening, body weight 80KG, blood pressure 164/102mmhg, sanity, spirit is poor, aphasia, abdominal distention, appetite still can, without feel sick tending to vomit, time feel nose heave, body of the tongue is slightly dark, and tongue is greasy in vain, stringy and hesitant pulse, neck is soft, and muscular strength 3 grades under upper right, right side pathology levies feminine gender.Head MRL shows multiple infarct, brain atrophy, and blood fat shows T-CHOL 8.12mol/L, triglyceride 5.26mol/L, HDL-C 0.79mol/L, low density cholesterol 5.53mol/L.Enter section's diagnosis: cerebral infarction, hyperlipemia.After entering section, routine gives thromboembolism preventing, improves the symptomatic treatments such as brain blood circulation, add simultaneously and use oral liquid of the present invention 20ml/ time, every day 3 times is oral, within 20 days, checks blood fat afterwards and shows 5.03mol/L, triglyceride 2.58mol/L, HDL-C 1.52mol/L, low density cholesterol 2.38mol/L, obviously improves when being comparatively admitted to hospital, evident in efficacy, advise low fat diet at ordinary times, continue oral maintaining treatment.
Name: so-and-so sex of Xu: man's age: 55 years old
Patient occurred dizzy, weak before last week, right hypochondriac region is uncomfortable, and dull pain increases the weight of to be admitted to hospital gradually, with inappetence, and abdominal distention, belch, hepatic region distension; Previously there is hypertension medical history 10 years; History of coronary heart disease 5 years.Have a medical check-up, 160/95mmhg, mind is clear, and spirit is poor, and chronic face, auscultation of lung no abnormality seen, heart circle expands to left down, heart rate 70 beats/min.A2>P2, abdominal tympanites, liver palpation of spleen owe satisfied, and Murphy levies feminine gender, has no liver distension of jugular vein.Other check: electrocardio illustrates: deficiency myocardial blood supply, ultrasonic prompting: severe fatty liver; Chemical examination blood fat, T-CHOL 7.2mmol/L, triglyceride 4.8mmol/L, low density lipoprotein, LDL 0.86mmol/L.Liver function: glutamic oxaloacetic transaminase, GOT 51mmol/L, glutamate pyruvate transaminase 78mmol/L, hepatitis B surface antigen (-) property, ultrasonic prompting: severe fatty liver; Clinical diagnosis: 1 fatty liver (severe) 2, hyperlipidemia 3, hypertension 2 grade 4, coronary heart disease; The following Therapeutic Method of main application, blood fat reducing, blood pressure lowering, coronary artery dilator blood vessel, waits symptomatic treatment, adds simultaneously and uses oral liquid of the present invention 20ml/ time, every day 3 times; Symptom obviously alleviates, and blood pressure stabilization is normal, and the electrocardiogram degree of ischemia amount of showing alleviates, and the aobvious amount of blood fat declines, significantly effectively reach clinical cure standard, the 23rd day check blood fat, T-CHOL 4.8mmol/L, triglyceride 1.5mmol/L, low-density albumen 3.21mmol/L, high-density protein 1.98mmol/L.Advise patient's low fat diet, moderate exercise, adhere to taking medicine, consolidate curative effect.
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (5)
1. be used for the treatment of a Chinese medicine preparation for fatty liver and hyperlipemia, it is characterized in that, its raw material comprises following Chinese medicine component: Rhizoma Curcumae, Radix Paeoniae Rubra, Fructus Crataegi, Herb Gynostemmae Pentaphylli, Semen Cassiae, Rhizoma Polygoni Cuspidati, Rhizoma Curcumae Longae, the Radix Astragali, Fructus Lycii.
2. the Chinese medicine preparation being used for the treatment of fatty liver and hyperlipemia according to claim 1, it is characterized in that, its raw material comprises the Chinese medicinal components of following mass parts: Rhizoma Curcumae 15 parts-75 parts, Radix Paeoniae Rubra 12 parts-60 parts, Fructus Crataegi 12 parts-60 parts, Herb Gynostemmae Pentaphylli 12 parts-60 parts, Semen Cassiae 12 parts-60 parts, Rhizoma Polygoni Cuspidati 15 parts-75 parts, 12 parts-60 parts, Rhizoma Curcumae Longae, the Radix Astragali 15 parts-75 parts, Fructus Lycii 15 parts-75 parts.
3. the Chinese medicine preparation being used for the treatment of fatty liver and hyperlipemia according to claim 2, it is characterized in that, its raw material comprises the Chinese medicinal components of following mass parts: Rhizoma Curcumae 15 parts, Radix Paeoniae Rubra 12 parts, Fructus Crataegi 12 parts, Herb Gynostemmae Pentaphylli 12 parts, Semen Cassiae 12 parts, Rhizoma Polygoni Cuspidati 15 parts, 12 parts, Rhizoma Curcumae Longae, the Radix Astragali 15 parts, Fructus Lycii 15 parts.
4. the Chinese medicine preparation being used for the treatment of fatty liver and hyperlipemia according to claim 2, it is characterized in that, its raw material comprises the Chinese medicinal components of following mass parts: choose Rhizoma Curcumae 30 parts, Radix Paeoniae Rubra 24 parts, Fructus Crataegi 24 parts, Herb Gynostemmae Pentaphylli 24 parts, Semen Cassiae 24 parts, Rhizoma Polygoni Cuspidati 30 parts, 24 parts, Rhizoma Curcumae Longae, the Radix Astragali 30 parts, Fructus Lycii 30 parts.
5. the Chinese medicine preparation being used for the treatment of fatty liver and hyperlipemia according to claim 2, it is characterized in that, its raw material comprises the Chinese medicinal components of following mass parts: choose Rhizoma Curcumae 75 parts, Radix Paeoniae Rubra 60 parts, Fructus Crataegi 60 parts, Herb Gynostemmae Pentaphylli 60 parts, Semen Cassiae 60 parts, Rhizoma Polygoni Cuspidati 75 parts, 60 parts, Rhizoma Curcumae Longae, the Radix Astragali 75 parts, Fructus Lycii 75 parts.
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| CN101244157A (en) * | 2007-02-15 | 2008-08-20 | 南京万舜源生物科技有限公司 | Natural plants extract, preparation method and application thereof |
| CN102423413A (en) * | 2012-01-04 | 2012-04-25 | 陈伯明 | Medicament for treating hyperlipemia and fatty liver and preventing atherosclerosis as well as applications thereof |
| CN103705854A (en) * | 2013-12-30 | 2014-04-09 | 郭兰春 | Semen cassiae, fructus lycii and glossy privet fruit oral solution with functions of tonifying liver and reducing fat |
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2014
- 2014-12-18 CN CN201410800220.2A patent/CN104491725B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101244157A (en) * | 2007-02-15 | 2008-08-20 | 南京万舜源生物科技有限公司 | Natural plants extract, preparation method and application thereof |
| CN102423413A (en) * | 2012-01-04 | 2012-04-25 | 陈伯明 | Medicament for treating hyperlipemia and fatty liver and preventing atherosclerosis as well as applications thereof |
| CN103705854A (en) * | 2013-12-30 | 2014-04-09 | 郭兰春 | Semen cassiae, fructus lycii and glossy privet fruit oral solution with functions of tonifying liver and reducing fat |
Non-Patent Citations (1)
| Title |
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| 钟周等: "140味降脂中药治疗高脂血症的用药规律分析", 《湖南中医药大学学报》 * |
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