CN104491482A - Traditional Chinese medicine composition for treating headache - Google Patents
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Abstract
The invention discloses a traditional Chinese medicine composition for treating headache. The traditional Chinese medicine composition for treating headache is prepared from the following materials in certain weight parts by virtue of combination: milkvetch root, scorpion, tall gastrodia tuber, Chinese starjasmine stem, szechuan lovage rhizome, processed kusnezoff monkshood root, vinegar rhizoma corydalis, wine fried Chinese angelica, paniculate swallowwort root, red sage root, gambir plant and fried myrrh. The traditional Chinese medicine composition has effects of removing blood stasis to relieve pain, calming endopathic wind to relieve convulsion, reducing blood pressure, treating headache and dizziness, treating common cold complicated with fright, expelling wind to remove dampness, cooling blood to reduce swelling, clearing heat to calm the liver, promoting circulation of air to stop pain, clearing away heart-fire to relieve restlessness, and eliminating head wind and headache, and has a relatively good effect on treating tension headache and migraine.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, specifically a kind of Chinese medicine composition for the treatment of headache.
Background technology
Modern society, a lot of youngster, can not regular diet because busy work, but also can regular staying up late, so that cause deficiency of the kidney overstrain, internal injury caused by excess of seven emotions, drinking and eating irregularly and cause headache, it is also usual with the symptom such as dizzy, tinnitus, deviation of the mouth with numbness and paralysis clinically.In city, the white collar of a lot of subhealth state often can be had a headache sense, regular with the symptom such as migraine, tinnitus.At present, for this focus, the therapeutic scheme that Western medicine provides not yet, or poor effect.
Summary of the invention
The invention provides a kind of Chinese medicine composition for the treatment of headache, it is mixed by the crude drug proportioning of following weight portion: Radix Astragali 5-15 part, Scorpio 2-8 part, Rhizoma Gastrodiae 5-15 part, Caulis Trachelospermi 5-15 part, Rhizoma Chuanxiong 5-15 part, Radix Aconiti Kusnezoffii Preparata 2-10 part, vinegar Rhizoma Corydalis 5-15 part, Radix Angelicae Sinensis (parched with wine) 5-15 part, Radix Cynanchi Paniculati 10-20 part, Radix Salviae Miltiorrhizae 25-35 part, Ramulus Uncariae Cum Uncis 25-35 part, Myrrha (parched) 5-15 part.
Optimum ratio is: Radix Astragali 7-13 part, Scorpio 2-6 part, Rhizoma Gastrodiae 7-13 part, Caulis Trachelospermi 7-13 part, Rhizoma Chuanxiong 7-13 part, Radix Aconiti Kusnezoffii Preparata 3-8 part, vinegar Rhizoma Corydalis 7-13, Radix Angelicae Sinensis (parched with wine) 7-13, Radix Cynanchi Paniculati 12-18 part, Radix Salviae Miltiorrhizae 27-33 part, Ramulus Uncariae Cum Uncis 27-33 part, Myrrha (parched) 7-13.
Optimum proportioning is: the Radix Astragali 10 parts, Scorpio 3 parts, 10 parts, Rhizoma Gastrodiae, Caulis Trachelospermi 10 parts, Rhizoma Chuanxiong 10 parts, Radix Aconiti Kusnezoffii Preparata 5 parts, vinegar Rhizoma Corydalis 10 parts, Radix Angelicae Sinensis (parched with wine) 10 parts, Radix Cynanchi Paniculati 15 parts, Radix Salviae Miltiorrhizae 30 parts, Ramulus Uncariae Cum Uncis 30 parts, Myrrha (parched) 10 parts.
It should be noted that: Chinese medicine composition of the present invention, when making decoction, need to decoct in advance Radix Aconiti Kusnezoffii Preparata, Ramulus Uncariae Cum Uncis finally puts into pot again.
Below in conjunction with the mechanism of action, traditional Chinese medical science combination principle of the present invention is described:
The Radix Astragali: there is good disease-prevention health effect;
Scorpio: there is " spasmolytic that relieves dizziness, high fever, infantile convulsions, epilepsy, etc., antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain " function;
Rhizoma Gastrodiae: can treat have a dizzy spell, the disease such as numb limbs and tense tendons, infantile convulsion;
Caulis Trachelospermi: there is dispelling wind and removing obstruction in the collateral, effect of removing heat from blood detumescence.Can be used for beriberoid pyretic arthralgia, the contracture of muscle arteries and veins, soreness of waist and knee joint, sore throat, carbuncle, injury from falling down;
Rhizoma Chuanxiong: excellent to blood circulation promoting and blood stasis dispelling, wind-expelling pain-stopping effectiveness, can control the diseases such as wind syndrome of head headache, rheumatic arthralgia;
Radix Aconiti Kusnezoffii Preparata: expelling wind and removing dampness, antalgic, for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic;
Vinegar Rhizoma Corydalis: have invigorate blood circulation, promoting the circulation of QI, the effect such as pain relieving;
Radix Angelicae Sinensis (parched with wine): there is benefiting blood and regulating blood circulation, menstruction regulating and pain relieving, moisturizes effect of laxation;
Radix Cynanchi Paniculati: for various pain diseases such as rheumatic arthralgia, lumbago, traumatic injury pain, abdominal pain, toothache, have dispelling wind for relieving itching effect;
Radix Salviae Miltiorrhizae: Radix Salviae Miltiorrhizae (Classification system: Salvia miltiorrhiza Bunge) has another name called Radix Salviae Miltiorrhizae, Radix Salviae Miltiorrhizae, Arisaema balansae Engl. etc.For dicotyledon Lamiaceae Salvia belongs to perennial vertical herbage plant, root manure is thick, outer vermilion, interior white, meat, and leaf is often imparipinnate leaf, top life or axillary-racemes; Bract lanceolar, calyx is bell, band purple, corolla hyacinthine, and style far ultraviolet is stretched, pyrene black, oval, the florescence 4-8 month, Hua Houjian fruit.Its root is a kind of Chinese medicine.Nature and flavor are bitter, are slightly cold.GUIXIN, Liver Channel.There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.Also there is blood fat reducing and antiatherogenic effect.
Ramulus Uncariae Cum Uncis: [nature and flavor] are sweet, cool.[return through] returns liver, pericardium channel.[function cures mainly] heat clearing away suppressing the hyperactive liver, dispelling wind and relieving convulsion.Dizzy for having a headache, dysphoric cold, infantile convulsion is twitched, pre-eclampsia; Hypertension.
Myrrha (parched): the effect with loose blood blood stasis removing, subduing swelling and relieving pain;
The present invention is with Radix Salviae Miltiorrhizae, Ramulus Uncariae Cum Uncis for monarch drug, and for stasis-dispelling and pain-killing, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion, reduces blood pressure, and treatment headache is dizzy, dysphoric cold, and infantile convulsion is twitched.
With Radix Cynanchi Paniculati, the Radix Astragali, Rhizoma Gastrodiae, Caulis Trachelospermi, Rhizoma Chuanxiong, vinegar Rhizoma Corydalis, Radix Angelicae Sinensis (parched with wine), Myrrha (parched) for ministerial drug, promoting blood circulation to restore menstrual flow, the detumescence of dispelling wind and removing obstruction in the collateral, removing heat from blood, wind-expelling pain-stopping, invigorate blood circulation, promoting the circulation of QI, pain relieving, loose blood blood stasis removing, subduing swelling and relieving pain.
Be adjuvant drug with Radix Aconiti Kusnezoffii Preparata, make with Scorpio, for expelling wind and removing dampness, antiinflammatory counteracting toxic substances, removing obstruction in the collateral to relieve pain.
Medicine of the present invention holds the marrow of the traditional Chinese medical science, rigorous prescription, and all medicine monarch share, and mends broken combination, brings out the best in each other, meet the principle of traditional Chinese medical science medicine law and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
Chinese medicine composition of the present invention has stasis-dispelling and pain-killing, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. arresting convulsion, reduce blood pressure, treatment headache is dizzy, dysphoric cold, effect of the detumescence of expelling wind and removing dampness, removing heat from blood, heat clearing away suppressing the hyperactive liver, promoting the circulation of QI pain relieving, the relieving restlessness that clears away heart-fire, the headache of elimination wind syndrome of head, has good therapeutic effect to treatment tension headache, migraine.
Clinical trial:
1, case is selected:
All kinds of headache 103 example of 2012-2013 application Drug therapy of the present invention.
2, diagnostic criteria:
Because cold, wind heat, rheumatism, Sunstroke cause headache due to invasion of exogenous pathogens 22 example, migraine 51, tension headache 19, etiology unknown headache 6 example.
3, therapeutic scheme
Take the made capsule of embodiment 4, each 4-6 grain, every 0.3g, the morning, noon and afternoon respectively once, 5 days are a course for the treatment of, statistical result after 2 courses for the treatment of.
4, the standard of curative effect evaluation:
Cure: headache disappears completely, does not recur in half a year; And headache complete incidence graph disappears, recidivist in half a year;
Effective: headache alleviates or slows down, but headache syndromes also exists;
Invalid: headache syndromes does not change, or increase the weight of, fail to respond to any medical treatment.
5, statistical result
Through statistics, above-mentioned 101 routine patients, take curative effect of medication of the present invention as follows:
Cure 92 examples: non-recidivist totally 73 examples in headache complete incidence graph half a year; Headache complete incidence graph disappears, recidivist's totally 19 examples in half a year, and wherein 18 examples are because of cold, liver-fire, suffer from a deficiency of the kidney and cause, after again taking medicine of the present invention, and headache syndromes complete incidence graph; Other case 1 example, this patient is other symptom, adopts other Regimen Chemotherapy;
Effective 6 examples: 6 routine medications are effective, but can not complete incidence graph;
Invalid 3 examples: 3 examples are invalid, adopt other therapeutic scheme to treat.
6, conclusion
According to above-mentioned diagnostic criteria, the standard of curative effect evaluation, according to test of cure scheme, treat because cold, wind heat, rheumatism, Sunstroke cause headache due to invasion of exogenous pathogens, migraine, tension headache, and etiology unknown is had a headache 101 routine patients, cure 92 examples, cure rate reaches 91.09%.Effective 6 examples, invalid 3 examples, total effective rate reaches 97.03%.Prove through above-mentioned test, medicine of the present invention is to treating because cold, wind heat, rheumatism, Sunstroke cause headache due to invasion of exogenous pathogens, migraine, tension headache, and etiology unknown headache has special efficacy.
Enumerate 3 representative cases below, to further illustrate the effect of medicine of the present invention:
1, Lee, female, 35 years old, symptom: head has vexed pain, constriction, had palpitation with tinnitus, nausea and vomiting symptom; After taking medicine continuously 10 days, transference cure, headache complete incidence graph.
2, through certain, man, 36 years old, symptom: the right half side migraine of head, daytime has a headache, and night is alleviated, noon severe headache, operating pressure is large, once in a while with insomnia, anxiety, tired mind; After taking medicine continuously 10 days, transference cure, headache complete incidence graph.
3, Xu certain, man, 30 years old, symptom: headache, the sense of discomfort after ear, under ear, with tinnitus, bulge of the ear, eye is vexed swollen; After taking medicine continuously 10 days, transference cure, headache complete incidence graph.
The present invention is as follows through results of pharmacodynamic test:
By 16 white mice at lumbar injection acetum, after injection there is abdominal part indent in white mice, and trunk and extremity are upheld, the behavior reactions such as hips up, and this shape is writhing response.
Randomly draw 10 white mice, wherein 5 give medicine of the present invention after white mice writhing number of times obviously reduce; Other 5 give aspirin medicine, and writhing number of times also obviously reduces.This tests proof, and this medicine has significant analgesic activity.
Acute toxicity test: larger dose and take to the growth of rat without remarkable toxicity compared with long-term therapy, have no overt toxicity damage to the chip form inspection such as brain, the heart, liver, kidney of rat and change, test display, this drug toxicity is very little.
Detailed description of the invention
embodiment 1:treat a Chinese medicine composition for headache, it is mixed by the crude drug proportioning of following weight portion: Radix Astragali 5-15 part, Scorpio 2-8 part, Rhizoma Gastrodiae 5-15 part, Caulis Trachelospermi 5-15 part, Rhizoma Chuanxiong 5-15 part, Radix Aconiti Kusnezoffii Preparata 2-10 part, vinegar Rhizoma Corydalis 5-15 part, Radix Angelicae Sinensis (parched with wine) 5-15 part, Radix Cynanchi Paniculati 10-20 part, Radix Salviae Miltiorrhizae 25-35 part, Ramulus Uncariae Cum Uncis 25-35 part, Myrrha (parched) 5-15 part.When making decoction, first decoct Radix Aconiti Kusnezoffii Preparata, Ramulus Uncariae Cum Uncis finally puts into pot again.
embodiment 2:the Chinese medicine composition for the treatment of headache according to claim 1, is characterized in that it is mixed by the crude drug proportioning of following weight portion: Radix Astragali 7-13 part, Scorpio 2-6 part, Rhizoma Gastrodiae 7-13 part, Caulis Trachelospermi 7-13 part, Rhizoma Chuanxiong 7-13 part, Radix Aconiti Kusnezoffii Preparata 3-8 part, vinegar Rhizoma Corydalis 7-13, Radix Angelicae Sinensis (parched with wine) 7-13, Radix Cynanchi Paniculati 12-18 part, Radix Salviae Miltiorrhizae 27-33 part, Ramulus Uncariae Cum Uncis 27-33 part, Myrrha (parched) 7-13.When making decoction, first decoct Radix Aconiti Kusnezoffii Preparata, Ramulus Uncariae Cum Uncis finally puts into pot again.
embodiment 3:the Chinese medicine composition for the treatment of headache according to claim 1, is characterized in that it is mixed by the crude drug proportioning of following weight portion: the Radix Astragali 10 parts, Scorpio 3 parts, 10 parts, Rhizoma Gastrodiae, Caulis Trachelospermi 10 parts, Rhizoma Chuanxiong 10 parts, Radix Aconiti Kusnezoffii Preparata 5 parts, vinegar Rhizoma Corydalis 10 parts, Radix Angelicae Sinensis (parched with wine) 10 parts, Radix Cynanchi Paniculati 15 parts, Radix Salviae Miltiorrhizae 30 parts, Ramulus Uncariae Cum Uncis 30 parts, Myrrha (parched) 10 parts.When making decoction, first decoct Radix Aconiti Kusnezoffii Preparata, Ramulus Uncariae Cum Uncis finally puts into pot again.
Chinese medicine composition of the present invention has effect of expelling wind and removing dampness, removing heat from blood detumescence, heat clearing away suppressing the hyperactive liver, promoting the circulation of QI pain relieving, the relieving restlessness that clears away heart-fire, wind syndrome of head headache, has good therapeutic effect to treatment tension headache, migraine.
2013, apply all kinds of headache 103 example of Drug therapy of the present invention clinically:
Wherein because cold, wind heat, rheumatism, Sunstroke cause headache due to invasion of exogenous pathogens 22 example, migraine 51, tension headache 19, etiology unknown headache 6 example.
Through statistics, above-mentioned 101 routine patients, take curative effect of medication of the present invention as follows:
Non-recidivist totally 73 examples in headache complete incidence graph half a year; Headache complete incidence graph, recidivist's totally 19 examples in half a year, wherein 18 examples are because of cold, liver-fire, suffer from a deficiency of the kidney and cause, after again taking medicine of the present invention, headache syndromes complete incidence graph, 1 example is other symptom, adopts other Regimen Chemotherapy; 6 routine medications are effective, but can not complete incidence graph; 3 examples are invalid, adopt other therapeutic scheme to treat.
Enumerate 3 representative cases below, to further illustrate the effect of medicine of the present invention:
Patient one, Lee, female, 35 years old, symptom: head has vexed pain, constriction, had palpitation with tinnitus, nausea and vomiting symptom; After taking medicine continuously 5 days, transference cure, headache complete incidence graph.
Patient two, through certain, man, 36 years old, symptom: the right half side migraine of head, daytime has a headache, and night is alleviated, noon severe headache, operating pressure is large, once in a while with insomnia, anxiety, tired mind; After taking medicine continuously 4 days, transference cure, headache complete incidence graph.
Patient three, Xu certain, man, 30 years old, symptom: headache, the sense of discomfort after ear, under ear, with tinnitus, bulge of the ear, eye is vexed swollen; After taking medicine continuously 5 days, transference cure, headache complete incidence graph.
embodiment 4:in embodiment 1-3, the dosage form of the Chinese medicine composition for the treatment of headache is decoction, oral liquid, capsule, tablet or pill.
Claims (5)
1. treat a Chinese medicine composition for headache, it is characterized in that it is mixed by the crude drug proportioning of following weight portion: Radix Astragali 5-15 part, Scorpio 2-8 part, Rhizoma Gastrodiae 5-15 part, Caulis Trachelospermi 5-15 part, Rhizoma Chuanxiong 5-15 part, Radix Aconiti Kusnezoffii Preparata 2-10 part, vinegar Rhizoma Corydalis 5-15 part, Radix Angelicae Sinensis (parched with wine) 5-15 part, Radix Cynanchi Paniculati 10-20 part, Radix Salviae Miltiorrhizae 25-35 part, Ramulus Uncariae Cum Uncis 25-35 part, Myrrha (parched) 5-15 part.
2. the Chinese medicine composition for the treatment of headache according to claim 1, is characterized in that it is mixed by the crude drug proportioning of following weight portion: Radix Astragali 7-13 part, Scorpio 2-6 part, Rhizoma Gastrodiae 7-13 part, Caulis Trachelospermi 7-13 part, Rhizoma Chuanxiong 7-13 part, Radix Aconiti Kusnezoffii Preparata 3-8 part, vinegar Rhizoma Corydalis 7-13, Radix Angelicae Sinensis (parched with wine) 7-13, Radix Cynanchi Paniculati 12-18 part, Radix Salviae Miltiorrhizae 27-33 part, Ramulus Uncariae Cum Uncis 27-33 part, Myrrha (parched) 7-13.
3. the Chinese medicine composition for the treatment of headache according to claim 1, is characterized in that it is mixed by the crude drug proportioning of following weight portion: the Radix Astragali 10 parts, Scorpio 3 parts, 10 parts, Rhizoma Gastrodiae, Caulis Trachelospermi 10 parts, Rhizoma Chuanxiong 10 parts, Radix Aconiti Kusnezoffii Preparata 5 parts, vinegar Rhizoma Corydalis 10 parts, Radix Angelicae Sinensis (parched with wine) 10 parts, Radix Cynanchi Paniculati 15 parts, Radix Salviae Miltiorrhizae 30 parts, Ramulus Uncariae Cum Uncis 30 parts, Myrrha (parched) 10 parts.
4. the Chinese medicine composition of the treatment headache according to claim 1 or 2 or 3, when it is characterized in that making decoction, first decoct Radix Aconiti Kusnezoffii Preparata, Ramulus Uncariae Cum Uncis finally puts into pot again.
5. the Chinese medicine composition of the treatment headache according to claim 1 or 2 or 3, is characterized in that its dosage form is decoction, capsule, tablet or pill.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103784763A (en) * | 2012-12-17 | 2014-05-14 | 唐焱华 | Traditional Chinese herbal medicine for treating migraine due to hyperactivity of liver-yang |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103784763A (en) * | 2012-12-17 | 2014-05-14 | 唐焱华 | Traditional Chinese herbal medicine for treating migraine due to hyperactivity of liver-yang |
Non-Patent Citations (4)
| Title |
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| 南京中医药大学编著: "《中药大辞典》", 30 March 2006, 上海科学技术出版社 * |
| 张冰主编: "《临床中药学》", 30 September 2012, 中国中医药出版社 * |
| 王珏: "偏头痛中医辨证治疗体会", 《中国中医急症》 * |
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Application publication date: 20150408 |