CN104491252A - Traditional Chinese medicine capable of promoting fracture postoperative wound to be healed - Google Patents

Traditional Chinese medicine capable of promoting fracture postoperative wound to be healed Download PDF

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CN104491252A
CN104491252A CN201510030738.7A CN201510030738A CN104491252A CN 104491252 A CN104491252 A CN 104491252A CN 201510030738 A CN201510030738 A CN 201510030738A CN 104491252 A CN104491252 A CN 104491252A
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崔合芳
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Abstract

The invention discloses a traditional Chinese medicine capable of promoting a fracture postoperative wound to be healed, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine is prepared from the following raw materials: angelica sinensis, safflower carthamus, corydalis tuber, lauraceae, deer sinew, rhizoma drynariae, radix achyranthis bidentatae, root or flower of toothedleaf torricellia, root of delavay ampelopsis, all-grass of esquirol coleus, thickleaf croton root, obscured homalomena rhizome, himalayan teasel root, Sanye tea, myrrh, frankincense, euonymus nitidus benth and liquorice root. The traditional Chinese medicine capable of promoting the fracture postoperative wound to be healed has a good treatment effect; a preparation process is simple and a preparation is stable; the traditional Chinese medicine is easy to popularize and apply.

Description

A kind of Chinese medicine promoting fracture surgery wound healing
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to a kind of Chinese medicine promoting fracture surgery wound healing.
Technical background
Fracture refers to a kind of disease because the reason such as wound or pathology causes sclerotin to rupture wholly or in part.Its main clinical manifestation is: fractures has localized pain and tenderness, local swelling and occur ecchymosis, and limb function is partially or completely lost, and completeness sclerotin still can occur cacomelia and abnormal movement.Because the feature of people to union of fracture lacks enough understanding, and lack the specific drug promoting union of fracture, often cause malunion of fracture or second fracture occurs.
At present for the principle of fractures: reset, fix and functional training, namely generally adopt operative reduction fracture affected part clinically, be fixed by draw point, steel plate, after a period of time, carry out rehabilitation by functional training.In rehabilitation course, owing to lacking the medicine that effectively can promote fracture wound healing, patient wound is in the state of inflammation, swelling for a long time, causes wound healing slow, brings the pain of health and the pressure of psychology to patient.
Summary of the invention
The object of the invention is to overcome the deficiencies in the prior art, a kind of Chinese medicine that can promote fracture surgery wound healing is fast and effectively provided.
In order to solve the problem, inventor's foundation tcm clinical practice experience for many years and the sclerotin feature of modern, provide a kind of Chinese medicine promoting fracture surgery wound healing, be made up of the raw material of following weight portion: Radix Angelicae Sinensis 10-14 part, Flos Carthami 8-12 part, Rhizoma Corydalis 8-12 part, white osmanthus 10-14 part, Ligamentum cervi 6-12 part, Rhizoma Drynariae 10-14 part, Radix Achyranthis Bidentatae 8-12 part, DAJIEGU 10-15 part, Radix Ampelopsis delavayanae 10-14 part, spend Folium Perillae 15-18 part in vain, Radix Crotonis Crassifolii 8-12 part, Rhizoma Homalomenae 5-9 part, Radix Dipsaci 12-15 part, three-leaf tea 16-20 part, Myrrha 6-9 part, Olibanum 8-12 part, China winged euonymus 6-9 part, Radix Glycyrrhizae 20-23 part.
Preferred Chinese medicine composition of the present invention is made up of the raw material of following weight portion: Radix Angelicae Sinensis 12 parts, 10 parts, Flos Carthami, Rhizoma Corydalis 10 parts, Bai Gui 12 parts, Ligamentum cervi 10 parts, Rhizoma Drynariae 12 parts, Radix Achyranthis Bidentatae 10 parts, DAJIEGU 13 parts, Radix Ampelopsis delavayanae 12 parts, spend Folium Perillae 16 parts, Radix Crotonis Crassifolii 10 parts, Rhizoma Homalomenae 8 parts, Radix Dipsaci 13 parts, three-leaf tea 17 parts, Myrrha 8 parts, Olibanum 10 parts, magnificent winged euonymus 8 parts, 22 parts, Radix Glycyrrhizae in vain.
Preparation technology's concrete steps of Chinese medicine composition of the present invention are:
Step 1, accurately to take by Chinese prescription of the present invention: Radix Angelicae Sinensis, Flos Carthami, Rhizoma Corydalis, Bai Gui, Ligamentum cervi, Rhizoma Drynariae, Radix Achyranthis Bidentatae, DAJIEGU, Radix Ampelopsis delavayanae, spend Folium Perillae, Radix Crotonis Crassifolii, Rhizoma Homalomenae, Radix Dipsaci, three-leaf tea, Myrrha, Olibanum, magnificent winged euonymus, Radix Glycyrrhizae in vain, pulverize respectively, then Homogeneous phase mixing together;
Step 2, add the purified water of 8 times of weight, backflow decocts 1.5-2.5 hour, and filter to get filtrate a; In filtering residue, add the purified water of 3 times of initial medical material weight, backflow decocts 1-2 hour, and filter to get filtrate b; In filtering residue, add the purified water of 2 times of initial medical material weight, backflow decoction 1 hour, filter to get filtrate c; By filtrate a, b, c mix, carry out concentrating under reduced pressure, until the relative density of mixed liquor is 1.17-1.25(70-75 DEG C of surveys) time stop concentrate, be the concentrated liquid of tradition Chinese medicine;
Step 3, routine techniques means according to the art, add adjuvant and make the Chinese medicine finished product preparation such as pill, granule or oral liquid by the concentrated liquid of tradition Chinese medicine.
The source of the present invention's Chinese crude drug used and effect:
Radix Angelicae Sinensis: hematonic; Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation, cure mainly all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.Select the dry root of umbelliferae angelica.
Flos Carthami: promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury, be suitable for various varicosis, peripheral neuritis, blood circulation is bad, lower limb numbness or the congestion such as livid purple.Select the dried floral of feverfew Flos Carthami.
Rhizoma Corydalis: invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, pain relieving.Cure mainly all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.Select the dry tuber of papaveraceae plant corydalis.
Bai Gui: expelling wind and cold; Blood circulation promoting and blood stasis dispelling.Main cold syndrome of the stomach gastralgia; Abdominal distention; Rheumatic arthralgia; Hemiplegia; Dysmenorrhea; Menoxenia; Anemofrigid cold; Measles; Traumatic injury; Fracture; Eczema.Select the leaf of the new Camphor tree in canella Yunnan, root bark or bark.
Ligamentum cervi: wind-damp dispelling, bone and muscle strengthening.Control strain, rheumatic arthritis, convulsion.Select the muscle of animal in deer family Cervus nippon Temminck or Cervus elaphus linnaeus extremity.
Rhizoma Drynariae: the kidney invigorating bone strengthening, continues and hinders pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.Select the dry rhizome of Plants of Polypodiaceae Mongolian oak Herba pteridii latiusculi.
Radix Achyranthis Bidentatae: invigorating the liver and kidney; Bone and muscle strengthening; Promoting blood circulation to restore menstrual flow; Ignite (blood) descending; Inducing diuresis for treating stranguria syndrome.Cure mainly soreness of waist and knee joint; Flaccidity and weakness of the lower limbs; Amenorrhea due to stagnation of blood; Dysmenorrhea; Puerperal abdominal pain due to blood stasis; Lump in the abdomen; Retention of placenta; Pyretic stranguria; Stranguria with blood; Traumatic injury; Carbuncle malignant boil.Select the root of amaranthaceous plant Radix Achyranthis Bidentatae.
DAJIEGU: promoting blood circulation to remove blood stasis, expelling wind and removing dampness.Fracture, traumatic injury, rheumatic arthritis, lumbago and skelalgia, traumatic hemorrhage.Acanthaceae Adhatoda Nees plant Ramulus Et Folium Adhatodae Vasicae Herb is selected to be used as medicine.
Radix Ampelopsis delavayanae: dispelling, collateral-activating, subduing swelling and detoxicating, hemostasia and promoting granulation.Dispelling the wind and dampness pathogens arthralgia pain, traumatic injury, fracture, carbuncle furuncle.Select root or the root bark of vitaceae trilobated leaf Caulis seu folium ampelopsis brevipedunculatae (Caulis Ampelopsis Brevipedunculae).
Spend Folium Perillae in vain: clearing away heat and expelling pathogen in the exterior; Expelling phlegm for arresting cough; Synthetism; Hemostasis.Main cold, fever; Lung abscess; Chronic cough is spat blood; Injury and bone fracture; Traumatic hemorrhage.Select root or the stem and leaf of labiate Herba Colei esquirolii.
Radix Crotonis Crassifolii: regulating QI to relieve pain, expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Treat for stomachache, flatulence, rheumatic arthralgia, traumatic injury.Select the root of euphorbia plant Radix Crotonis Crassifolii.
Rhizoma Homalomenae: wind-damp dispelling, strengthening bone and muscle, pain relieving, detumescence.Dispelling the wind and dampness pathogens arthralgia pain, podomere is ached, and muscles and bones flaccidity is soft, stomachache, and carbuncle skin ulcer swells.For rheumatic arthralgia, chills and pain of the waist and kness, lower limb contracture numbness.Araeceae is selected to put down a dry rhizome for taro platymiscium Rhizoma Homalomenae.
Radix Dipsaci: invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Cure mainly aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer swells.Select the root of Dipsacaceae herbaceos perennial Radix Dipsaci.
Three-leaf tea: expelling wind and removing dampness; Removing toxic substances dissipating blood stasis.Main air pain of dampness syndrome; Oedema due to nephritis; Cirrhotic ascites; Injury and bone fracture.Select the Herb of sapindaceous plant ripple leaf Radix Allophylli Viridis.
Myrrha: loose blood blood stasis removing, subduing swelling and relieving pain.Cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, mass in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There is the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation.Select the gum resin of olive subject plant myrrh or Alan fort myrrh.
Olibanum: regulating qi and activating blood, analgesic therapy, chases after poison, has strong bacteriostasis, and effectively can kill infusorian.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select the scented resin containing volatile oil of olive subject plant Olibanum wood output.
China's winged euonymus: expelling wind and removing dampness; Strong muscles and bones.Cure mainly lumbago, skelalgia of rheumatism, lumbago due to renal deficiency, traumatic injury, hypertension.Select the Herb of Celastraceae plant China winged euonymus.
Radix Glycyrrhizae: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.Select the dry root of glycyrrhizic legume or Glycyrrhiza inflata Bat..
The prescription analysis of Chinese medicine of the present invention:
Chinese medicine of the present invention is with reducing swelling and alleviating pain on medical material is selected, and hemostasia and promoting granulation is main, has effect of blood yiqi, expelling wind and cold concurrently; All medicines coordinates, and mutually coordinates, combined effect, can blood circulation promoting and blood stasis dispelling, strong muscles and bones, thus promote affected bone quickly-healing.
Compared with prior art, Chinese medicine of the present invention has treating both the principal and secondary aspects of a disease, the advantage such as evident in efficacy, and general strong adaptability, preparation technology is easy, is easy to apply.
Detailed description of the invention
Embodiment 1
1) accurately take by Chinese prescription of the present invention: Radix Angelicae Sinensis 1200g, Flos Carthami 1000g, Rhizoma Corydalis 1000g, Bai Gui 1200g, Ligamentum cervi 1000g, Rhizoma Drynariae 1200g, Radix Achyranthis Bidentatae 1000g, DAJIEGU 1300g, Radix Ampelopsis delavayanae 1200g, spend Folium Perillae 1600g, Radix Crotonis Crassifolii 1000g, Rhizoma Homalomenae 800g, Radix Dipsaci 1300g, three-leaf tea 1700g, Myrrha 800g, Olibanum 1000g, magnificent winged euonymus 800g, Radix Glycyrrhizae 2200g in vain, pulverize respectively, mixing;
2) add the purified water of 8 times of weight, backflow decoction 2 hours, filter to get filtrate a; In filtering residue, add the purified water of the initial medical material weight of initial medical material 3 times, backflow decoction 1.5 hours, filter to get filtrate b; In filtering residue, add the purified water of the initial medical material weight of initial medical material 2 times, backflow decoction 1 hour, filter to get filtrate c; By filtrate a, b, c mix, carry out concentrating under reduced pressure, until the relative density of mixed liquor is 1.20(73 DEG C of surveys) time stop concentrate, be the concentrated liquid of tradition Chinese medicine;
3) the concentrated liquid of tradition Chinese medicine is added adjuvant and make granule, amount to crude drug content and be about 0.24g crude drug/g granule.
Embodiment 2
1) accurately take by Chinese prescription of the present invention: Radix Angelicae Sinensis 1000g, Flos Carthami 800g, Rhizoma Corydalis 800g, Bai Gui 1000g, Ligamentum cervi 600g, Rhizoma Drynariae 1000g, Radix Achyranthis Bidentatae 800g, DAJIEGU 1000g, Radix Ampelopsis delavayanae 1000g, spend Folium Perillae 1500g, Radix Crotonis Crassifolii 800g, Rhizoma Homalomenae 500g, Radix Dipsaci 1200g, three-leaf tea 1600g, Myrrha 600g, Olibanum 800g, magnificent winged euonymus 600g, Radix Glycyrrhizae 2000g in vain, pulverize respectively, mixing;
2) add the purified water of 8 times of weight, backflow decoction 2 hours, filter to get filtrate a; In filtering residue, add the purified water of the initial medical material weight of initial medical material 3 times, backflow decoction 1.5 hours, filter to get filtrate b; In filtering residue, add the purified water of the initial medical material weight of initial medical material 2 times, backflow decoction 1 hour, filter to get filtrate c; By filtrate a, b, c mix, carry out concentrating under reduced pressure, until the relative density of mixed liquor is 1.20(73 DEG C of surveys) time stop concentrate, be the concentrated liquid of tradition Chinese medicine;
3) the concentrated liquid of tradition Chinese medicine is added adjuvant and make granule, amount to crude drug content and be about 0.24g crude drug/g granule.
Embodiment 3
1) accurately take by Chinese prescription of the present invention: Radix Angelicae Sinensis 1400g, Flos Carthami 1200g, Rhizoma Corydalis 1200g, Bai Gui 1400g, Ligamentum cervi 1200g, Rhizoma Drynariae 1400g, Radix Achyranthis Bidentatae 1200g, DAJIEGU 1500g, Radix Ampelopsis delavayanae 1400g, spend Folium Perillae 1800g, Radix Crotonis Crassifolii 1200g, Rhizoma Homalomenae 900g, Radix Dipsaci 1500g, three-leaf tea 2000g, Myrrha 900g, Olibanum 1200g, magnificent winged euonymus 900g, Radix Glycyrrhizae 2300g in vain, pulverize respectively, mixing;
2) add the purified water of 8 times of weight, backflow decoction 2 hours, filter to get filtrate a; In filtering residue, add the purified water of the initial medical material weight of initial medical material 3 times, backflow decoction 1.5 hours, filter to get filtrate b; In filtering residue, add the purified water of the initial medical material weight of initial medical material 2 times, backflow decoction 1 hour, filter to get filtrate c; By filtrate a, b, c mix, carry out concentrating under reduced pressure, until the relative density of mixed liquor is 1.20(73 DEG C of surveys) time stop concentrate, be the concentrated liquid of tradition Chinese medicine;
3) the concentrated liquid of tradition Chinese medicine is added adjuvant and make granule, amount to crude drug content and be about 0.24g crude drug/g granule.
The animal toxicity test of embodiment 4 Chinese medicine granules of the present invention
(1) test drug: Chinese medicine granules obtained by embodiment of the present invention 1-3, is modulated into solution by purified water by 1 ﹕ 1.Test animal used: regular grade NIH mice, body weight 21g ± 5g, male and female half and half, female mice is all without pregnant; SD rat, original body mass 215g ± 7g, male and female half and half, female rats is all without pregnant.
(2) acute toxicity test
Application mice carries out acute toxicity testing and shows: the By Chinese Medicines that mouse stomach modulates, under 600g crude drug/kg dosage, after administration, mice occurs that light activity reduces, 1 hours recovers normal, Continuous Observation 7 days after administration, none dead mouse, and overall health of patients, diet, take the photograph water, urine and body weight increase all normal.Experimental result shows: the maximum dosage-feeding of mouse stomach Chinese medicine granules of the present invention is 600g crude drug/kg/d(LD50 > 600g crude drug/kg).Chinese medicine preparation clinical application every day total amount of the present invention is 0.12g crude drug/kg/d; By weighing machine, the dosis tolerata of mouse stomach Chinese medicine preparation of the present invention is 5000 times of clinical patient.Point out this medicine acute toxicity extremely low, clinical drug safety.
(3) long term toxicity test
Select SD rat, give the Chinese medicine granules of the present invention of Three doses: 21.6g crude drug/kg, 7.2g crude drug/kg, 2.4g crude drug/kg(per weight dosage is by 20 times of calculating of clinical application amount, and clinical application amount is according to Pharmacopoeia of the People's Republic of China version in 2010).Every day gavage once, continuous 90 days, after last administration 24 hours respectively group live and kill 1/2 animal (male and female half and half), all the other 1/2 animals continue that observations are alive after 2 weeks kills.Duration of test observes outward appearance, general behavior, food ration, the body weight change of animal; Within after administration 90 days, within 2 weeks, carry out the index checking such as hematology's (RBC, HB, reticulocyte, PLT, CT, WBC and classification) and blood biochemical (AST, ALT, ALP, Glu, BUN, Crea, TP, T.BIL, ALB, CHOL), urine biochemistry, organ coefficient, histopathology with drug withdrawal.
Result of the test shows: Chinese medicine preparation of the present invention is good at high, medium and low dosage treated animal general state, and outward appearance sign, behavioral activity, food-intake and body weight increase change all without exception; Three dosage groups and matched group hematological examination, blood biochemical analysis, urine biochemical analysis all in normal range, without significant difference between group; Each group of main organs histopathological examination shows no obvious abnormalities.These parameters drug withdrawal also had no change after 2 weeks.This test dosage is respectively 180,60,20 times of clinical medicine dose, according to result of the test: Chinese medicine preparation of the present invention has no significant effect rat in high, medium and low three dosage (21.6g crude drug/kg, 7.2g crude drug/kg, 2.4g crude drug/kg) administration in continuous 90 days, without clear and definite toxicity target organ and sensitive indicator, convalescent period observation also has no retardance toxic reaction, points out the dose safety of Chinese medicine preparation clinical practice of the present invention very high.
Embodiment 5 Chinese medicine composition of the present invention affects mouse hot-plate analgesic
1) mouse hot-plate pain model makes
By the regular grade NIH male mice of body weight 21g ± 5g, be placed on hot plate dolorimeter, screen qualified male mice 90 (to lick metapedes time <5s or >30s to throw aside, scald for preventing foot, also deadline should be established, be generally 60s), the incubation period of metapedes reaction is added for threshold of pain index with mice, get 60 male NIH mices, be divided into 5 groups, 12/group, i.e. model group, dolantin group, Chinese medicine composition of the present invention (obtaining by Chinese medicine composition prescription described in embodiment 1 and preparation technology) low dose group, middle dosage group and high dose group.Each group is gastric infusion, and 1 times/day, dosage is as shown in table 1, and after successive administration 14d, after measuring last medicine, 60min, 120min add the time of foot reaction.
2) Chinese medicine composition of the present invention is on the impact of licking the foot response latency in mouse hot-plate analgesic experiment
Mice licks foot response latency time showing, compare with model group, after administration after 1h and 2h, the incubation period that the mice of each administration group of Chinese medicine composition of the present invention adds foot reaction is all greater than model group, there is dose-dependence, and be significantly greater than model group (P < 0.05) incubation period of high dose group.What illustrate that this Chinese medicine composition of the present invention can extend that mice stimulates hot plate adds the sufficient response latency, has certain analgesic activity.Under same experiment condition, positive control drug dolantin group (1h, P < 0.05; 2h, P < 0.01) also significant prolongation mice add the incubation period of foot reaction, have certain analgesic activity.The results are shown in Table 1.
Table 1 mice lick foot response latency timetable ( )
Note: compare with model group, * P < 0.05, * * P < 0.01.
Embodiment 6, clinical effectiveness are tested
1, experimenter's data
Experimenter all from certain urgent disorder in orthopaedics hospital fracture patient that in June, 2012 to 2013, year December was accepted for medical treatment, therefrom select be applicable to test patient 100 example, wherein man 68 example, age 17-55 year, female 32 example, age 20-60 year; Wherein fracture of rib 23 example, humeral fracture 36 example, Fracture of femur 13 example, Phalangeal fracture 18 example, knee joint comminuted fracture 10 example, patient all adopts operative treatment to fix injured skeleton.
2, test method
Experimenter takes the Chinese medicinal granule obtained by the embodiment of the present invention 1, every day 2 times, and it is 3.6g that each 15g(amounts to crude drug), more than 8 hours, interval.Within 4 weeks, be a course for the treatment of, treat 3 courses for the treatment of continuously.In therapeutic process, cured person can depart from treatment at any time, simultaneously the situation such as health, untoward reaction of record patient.
3, evaluation criterion
(1) cure: the transference cure such as pain, swelling at impaired place, by x-ray, film making inspection is carried out to fracture, find that damaged part heals completely.
(2) effective: the transference cure such as pain, swelling at impaired place, by x-ray, film making inspection is carried out to fracture, find that damaged part has been clearly better, substantially heal.
(3) invalid: the symptom such as pain, swelling at impaired place is improved slowly, carries out film making inspection by x-ray to fracture, find that damaged part healing situation is poor, indolence.
4, result of the test
Table 2 result of the test statistical analysis table
5, conclusion (of pressure testing)
As can be seen from the test results, the cure rate of Chinese medicine preparation of the present invention is up to (32%), total effective rate is 97%, untoward reaction is not had after patient medication, as can be seen from these data, Chinese medicine preparation of the present invention particularly embodiment 1 is prepared medicine and is had very significant curative effect for fracture surgery wound healing, obtains beat all technological achievement.

Claims (4)

1. promote a Chinese medicine for fracture surgery wound healing, it is characterized in that being made up of the raw material of following weight portion: Radix Angelicae Sinensis 10-14 part, Flos Carthami 8-12 part, Rhizoma Corydalis 8-12 part, Bai Gui 10-14 part, Ligamentum cervi 6-12 part, Rhizoma Drynariae 10-14 part, Radix Achyranthis Bidentatae 8-12 part, DAJIEGU 10-15 part, Radix Ampelopsis delavayanae 10-14 part, spend Folium Perillae 15-18 part, Radix Crotonis Crassifolii 8-12 part, Rhizoma Homalomenae 5-9 part, Radix Dipsaci 12-15 part, three-leaf tea 16-20 part, Myrrha 6-9 part, Olibanum 8-12 part, magnificent winged euonymus 6-9 part, Radix Glycyrrhizae 20-23 part in vain.
2. promote the Chinese medicine of fracture surgery wound healing according to claim 1, it is characterized in that being made up of the raw material of following weight portion: Radix Angelicae Sinensis 12 parts, 10 parts, Flos Carthami, Rhizoma Corydalis 10 parts, Bai Gui 12 parts, Ligamentum cervi 10 parts, Rhizoma Drynariae 12 parts, Radix Achyranthis Bidentatae 10 parts, DAJIEGU 13 parts, Radix Ampelopsis delavayanae 12 parts, spend Folium Perillae 16 parts, Radix Crotonis Crassifolii 10 parts, Rhizoma Homalomenae 8 parts, Radix Dipsaci 13 parts, three-leaf tea 17 parts, Myrrha 8 parts, Olibanum 10 parts, magnificent winged euonymus 8 parts, 22 parts, Radix Glycyrrhizae in vain.
3. according to claim 1 or 2, promote the Chinese medicine of fracture surgery wound healing, it is characterized in that: described Chinese medicine is pill, granule or oral liquid.
4. described in claim 1 or 2, promote that the Chinese medicine of fracture surgery wound healing promotes the application in fracture surgery wound healing medicine in preparation.
CN201510030738.7A 2015-01-22 2015-01-22 Traditional Chinese medicine capable of promoting fracture postoperative wound to be healed Withdrawn CN104491252A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103223076A (en) * 2013-04-16 2013-07-31 漯河医学高等专科学校 Orally taken traditional Chinese medicine treating fractures

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103223076A (en) * 2013-04-16 2013-07-31 漯河医学高等专科学校 Orally taken traditional Chinese medicine treating fractures

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Application publication date: 20150408