CN104491248A - Drug for treating primary thrombocythemia and preparation method thereof - Google Patents
Drug for treating primary thrombocythemia and preparation method thereof Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/739—Sanguisorba (burnet)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
Abstract
The invention discloses a drug for treating primary thrombocythemia and a preparation method thereof. The drug is prepared from the following raw material medicine by weight: 1-2g of unguis hominis, 5-10g of levant cotton exocarp, 2-3g of sensitive plant, 2-4g of lycopodium clavatum, 2-6g of akebiaquinata, 2-4g of esliptae herba, 4-8g of cactus, 2-6g of spathiphyllum, 4-8g of epiphy hum, 3-6g of youth-and-old-age, 1-2g of aspongopus, 3-7g of unicorn beetle, 2-7g of gallnut, 2-6g of semen lini, 3-8 g of sweet wormwood, 2-5g of rattletop, 0.2-0.5g of stalactite, 2-5g of Chinese pulsatilla root and 3-5g of garden burnet.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of primary thrombocytosis and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Primary thrombocytosis (thrombocythe-mia) is the not bright Chronic Myeloid proliferative disease of a kind of reason, because often having Repeated Hemorrhage, therefore also referred to as " hemorrhagic thrombocythemia ", it is characterized by bone marrow megakaryocyte paraplasm companion platelet to continue to increase, simultaneously with the slight hypertrophy of other hematopoietic cells, thrombosis and spleen enlargement.
Age of onset is common with more than 40 years old, and the lighter only has giddy, weak, and severe one has hemorrhage, thrombosis, and hemorrhage be often spontaneity, and recurrent exerbation, is common in gastrointestinal tract and epistaxis; Secondly hematuria and skin, mucosa ecchymosis, incidence of thrombus is lower than hemorrhage, and common extremity vascular thromboembolism, causes numb hand and foot, pain, even bad subcutaneous ulcer, and spleen and mesenteric embolism can cause stomachache, and lung, brain, kidney also thromboembolism can occur.Important organ has thrombosis and the hemorrhage normal main cause lethal for primary disease.
Belong to Chinese medicine " blood is real ", " marrow is real ", " gathering " category, onset is slow, prolonged illness deficiency of kidney-essence, and liver-yin secretly consumes, therefore controls suitable Zishen Qinggan, dredges to regulate the flow of vital energy, blood circulation promoting and blood stasis dispelling.
Summary of the invention
The object of the invention is for the deficiencies in the prior art, a kind of medicine for the treatment of primary thrombocytosis and preparation method thereof is provided, the drug side effect of this treatment primary thrombocytosis is little, can maintain the platelet normal time long, can prevent bone marrow from seriously suppressing.
For solving the problem, the present invention by the following technical solutions:
Treat a medicine for primary thrombocytosis, it is characterized in that: be made up of the crude drug of following weight: Concha 1-2g, Exocarpium Gossypii 5-10g, Herba Mimosae Pudicae 2-3g, Herba Lycopodii 2-4g, Caulis Akebiae 2-6g, Herba Ecliptae 2-4g, Radix et Caulis Opuntiae Dillenii 4-8g, slap 2-6g, Flos Epiphylli Oxypetali 4-8g, youth-and-old-age 3-6g, Aspongopus 1-2g, Allomyrinadichotoma 3-7g, Galla Chinensis 2-7g, Semen Lini 2-6g, Herba Artemisiae Annuae 3-8g, Rhizoma Cimicifugae 2-5g, Stalactitum 0.2-0.5g, Radix Pulsatillae 2-5g, Radix Sanguisorbae 3-5g in vain.
Below the further improvement to technique scheme:
Treat a medicine for primary thrombocytosis, it is characterized in that: be made up of the crude drug of following weight: Concha 1.5g, Exocarpium Gossypii 8g, Herba Mimosae Pudicae 1.5g, Herba Lycopodii 3g, Caulis Akebiae 4g, Herba Ecliptae 3g, Radix et Caulis Opuntiae Dillenii 6g, slap 4g, Flos Epiphylli Oxypetali 6g, youth-and-old-age 5g, Aspongopus 1.5g, Allomyrinadichotoma 4g, Galla Chinensis 4g, Semen Lini 3g, Herba Artemisiae Annuae 5g, Rhizoma Cimicifugae 3g, Stalactitum 0.3g, Radix Pulsatillae 3g, Radix Sanguisorbae 4g in vain.
Below the further improvement to technique scheme:
A kind of preparation method for the treatment of the medicine of primary thrombocytosis comprises the following steps:
1) Herba Mimosae Pudicae of above-mentioned weight, Herba Lycopodii, Caulis Akebiae, Herba Ecliptae, the white palm, youth-and-old-age, Aspongopus, Galla Chinensis, Semen Lini, Rhizoma Cimicifugae, Stalactitum, the Radix Pulsatillae, Radix Sanguisorbae, is got, be heated to boiling, slow fire boiling 10-20 minute, then add the Radix et Caulis Opuntiae Dillenii of above-mentioned weight simultaneously, Herba Artemisiae Annuae decocts 10-20 minute, the Flos Epiphylli Oxypetali intense fire finally adding above-mentioned weight decocts 5 minutes; Leach to obtain medicinal liquid A;
2), Exocarpium Gossypii is added the yellow wine of Exocarpium Gossypii weight 3 times of weight; Decoct, continue to decoct 5-10 minute after keeping boiling; Obtain Exocarpium Gossypii wine liquid B;
3), by the Concha of above-mentioned quality burn till carbon shape and wear into fine powder, add Concha 5 times of weight yellow wine and stir, obtain fingernail yellow wine soup C;
4), by the Allomyrinadichotoma of above-mentioned quality be placed on vinegar and steam 10-20 minute, then pulverize, obtain vinegar Allomyrinadichotoma D;
5), by medicinal liquid A, Exocarpium Gossypii wine liquid B, fingernail yellow wine soup C and vinegar Allomyrinadichotoma D mix, i.e. the medicine of obtained treatment primary thrombocytosis.
Below the further improvement to technique scheme:
Described Allomyrinadichotoma scalds Allomyrinadichotoma adult after death for boiled water.
Divide and sooner or later respectively take once after meal; it within 10 days, is a course for the treatment of; generally take 2-3 the course for the treatment of symptom can greatly alleviate; chemically examine after taking 3 courses for the treatment of; thrombocytopenia is to normal or close to normal value; get final product drug withdrawal; check afterwards weekly; if platelet value rebounds; can continue to take medicine, after general drug withdrawal, platelet is normal value and is more than 2 weeks close to the time of normal value, and the drug side effect of this treatment primary thrombocytosis is little; the platelet normal time can be maintained long, can prevent bone marrow from seriously suppressing.
When taking medicine of the present invention, abstain from flesh and fish irritable food, abstains from smoking and drinking, and is careful in one's diet, and take this medicine and likely cause and be hard and dry and difficult defecation, the decapacitation of this medicine of long-term taking causes outside difficult defecation, without other apparent side effects, and can long-term taking.
Below in conjunction with detailed description of the invention to technical scheme further instruction of the present invention.
Detailed description of the invention
Embodiment 1, treat a medicine for primary thrombocytosis, be made up of the crude drug of following weight: Concha 1.5g, Exocarpium Gossypii 8g, Herba Mimosae Pudicae 1.5g, Herba Lycopodii 3g, Caulis Akebiae 4g, Herba Ecliptae 3g, Radix et Caulis Opuntiae Dillenii 6g, slap 4g, Flos Epiphylli Oxypetali 6g, youth-and-old-age 5g, Aspongopus 1.5g, Allomyrinadichotoma 4g, Galla Chinensis 4g, Semen Lini 3g, Herba Artemisiae Annuae 5g, Rhizoma Cimicifugae 3g, Stalactitum 0.3g, Radix Pulsatillae 3g, Radix Sanguisorbae 4g in vain.
Said medicine is prepared according to following step:
Get the Concha of above-mentioned weight, Exocarpium Gossypii, Herba Mimosae Pudicae, Herba Lycopodii, Caulis Akebiae, Herba Ecliptae, Radix et Caulis Opuntiae Dillenii, the white palm, Flos Epiphylli Oxypetali, youth-and-old-age, Aspongopus, Allomyrinadichotoma, Galla Chinensis, Semen Lini, Herba Artemisiae Annuae, Rhizoma Cimicifugae, Stalactitum, the Radix Pulsatillae, Radix Sanguisorbae, slow fire boiling 20-40 minute, the Flos Epiphylli Oxypetali intense fire then adding above-mentioned weight decocts 5 minutes; Leach treatment primary thrombocytosis medicine.
Embodiment 2, treat a medicine for primary thrombocytosis, be made up of the crude drug of following weight: Concha 1g, Exocarpium Gossypii 5g, Herba Mimosae Pudicae 2g, Herba Lycopodii 2g, Caulis Akebiae 2g, Herba Ecliptae 2g, Radix et Caulis Opuntiae Dillenii 4g, slap 2g, Flos Epiphylli Oxypetali 4g, youth-and-old-age 3g, Aspongopus 1g, Allomyrinadichotoma 3g, Galla Chinensis 2g, Semen Lini 2g, Herba Artemisiae Annuae 3g, Rhizoma Cimicifugae 2g, Stalactitum 2g, Radix Pulsatillae 2g, Radix Sanguisorbae 3g in vain.
Get the Concha of above-mentioned weight, Exocarpium Gossypii, Herba Mimosae Pudicae, Herba Lycopodii, Caulis Akebiae, Herba Ecliptae, Radix et Caulis Opuntiae Dillenii, the white palm, Flos Epiphylli Oxypetali, youth-and-old-age, Aspongopus, Allomyrinadichotoma, Galla Chinensis, Semen Lini, Herba Artemisiae Annuae, Rhizoma Cimicifugae, Stalactitum, the Radix Pulsatillae, Radix Sanguisorbae, slow fire boiling 20-40 minute, the Flos Epiphylli Oxypetali intense fire then adding above-mentioned weight decocts 5 minutes; Leach treatment primary thrombocytosis medicine.
Embodiment 3, treat a medicine for primary thrombocytosis, be made up of the crude drug of following weight: Concha 2g, Exocarpium Gossypii 10g, Herba Mimosae Pudicae 3g, Herba Lycopodii 4g, Caulis Akebiae 6g, Herba Ecliptae 4g, Radix et Caulis Opuntiae Dillenii 8g, slap 6g, Flos Epiphylli Oxypetali 8g, youth-and-old-age 6g, Aspongopus 2g, Allomyrinadichotoma 7g, Galla Chinensis 7g, Semen Lini 6g, Herba Artemisiae Annuae 8g, Rhizoma Cimicifugae 5g, Stalactitum 5g, Radix Pulsatillae 5g, Radix Sanguisorbae 5g in vain.
Get the Concha of above-mentioned weight, Exocarpium Gossypii, Herba Mimosae Pudicae, Herba Lycopodii, Caulis Akebiae, Herba Ecliptae, Radix et Caulis Opuntiae Dillenii, the white palm, Flos Epiphylli Oxypetali, youth-and-old-age, Aspongopus, Allomyrinadichotoma, Galla Chinensis, Semen Lini, Herba Artemisiae Annuae, Rhizoma Cimicifugae, Stalactitum, the Radix Pulsatillae, Radix Sanguisorbae, slow fire boiling 20-40 minute, the Flos Epiphylli Oxypetali intense fire then adding above-mentioned weight decocts 5 minutes; Leach treatment primary thrombocytosis medicine.
The medicine obtained to embodiment 1, embodiment 2 and embodiment 3 carries out clinical trial; primary thrombocytosis is suffered to making a definite diagnosis; take the medicine that embodiment 1, embodiment 2 and embodiment 3 is obtained respectively; sooner or later taking medicine after meal; it within 10 days, is a course for the treatment of; generally take 2-3 the course for the treatment of symptom can greatly alleviate; chemically examine after taking 3 courses for the treatment of; platelet is normal or close to normally getting final product drug withdrawal; check after drug withdrawal 2 weeks, as platelet gos up then to continue to take medicine, as still abnormal in platelet after taking 3 courses for the treatment of; then continue to take medicine, repeatedly check.
Through overtesting, the drug effect of the medicine that embodiment 1 is obtained is better than embodiment 2 and embodiment 3, and the drug effect of the medicine of embodiment 3 and embodiment 2 is very nearly the same, and result of the test is in table one.
Table one
| Embodiment 1 | Take medicine and have 3 courses for the treatment of Platelet of 65% obviously to reduce, symptom alleviates | Take medicine and have 6 courses for the treatment of Platelet of 68% normal, transference cure, 10% platelet declines, and symptom alleviates, and all the other are not improved | Have the patient of 70% after the normal patient's drug withdrawal of platelet, the interval time that platelet rises again was more than two months |
| Embodiment 2 | Take medicine and have 3 courses for the treatment of Platelet of 58% obviously to reduce, symptom alleviates | Take medicine and have 6 courses for the treatment of Platelet of 60% normal, transference cure, 6% platelet declines, and symptom alleviates, and all the other are not improved | Have the patient of 58% after the normal patient's drug withdrawal of platelet, the interval time that platelet rises again was more than two months |
| Embodiment 3 | Take medicine and have 3 courses for the treatment of Platelet of 56% obviously to reduce, symptom alleviates | Take medicine and have 6 courses for the treatment of Platelet of 58% obviously to reduce, symptom alleviates, and 7% platelet declines, and symptom alleviates, and all the other are not improved | Have the patient of 60% after the normal patient's drug withdrawal of platelet, the interval time that platelet rises again was more than two months |
Embodiment 4, treat a medicine for primary thrombocytosis, be made up of the crude drug of following weight: Concha 1.5g, Exocarpium Gossypii 8g, Herba Mimosae Pudicae 1.5g, Herba Lycopodii 3g, Caulis Akebiae 4g, Herba Ecliptae 3g, Radix et Caulis Opuntiae Dillenii 6g, slap 4g, Flos Epiphylli Oxypetali 6g, youth-and-old-age 5g, Aspongopus 1.5g, Allomyrinadichotoma 4g, Galla Chinensis 4g, Semen Lini 3g, Herba Artemisiae Annuae 5g, Rhizoma Cimicifugae 3g, Stalactitum 3g, Radix Pulsatillae 3g, Radix Sanguisorbae 4g in vain.
1) Herba Mimosae Pudicae of above-mentioned weight, Herba Lycopodii, Caulis Akebiae, Herba Ecliptae, the white palm, youth-and-old-age, Aspongopus, Galla Chinensis, Semen Lini, Rhizoma Cimicifugae, Stalactitum, the Radix Pulsatillae, Radix Sanguisorbae, is got, be heated to boiling, slow fire boiling 10-20 minute, then add the Radix et Caulis Opuntiae Dillenii of above-mentioned weight simultaneously, Herba Artemisiae Annuae decocts 10-20 minute, the Flos Epiphylli Oxypetali intense fire finally adding above-mentioned weight decocts 5 minutes; Leach to obtain medicinal liquid A;
2), Exocarpium Gossypii is added the yellow wine of Exocarpium Gossypii weight 3 times of weight; Decoct, continue to decoct 5-10 minute after keeping boiling; Obtain Exocarpium Gossypii wine liquid B;
3), by the Concha of above-mentioned quality wear into fine powder, add Concha 5 times of weight yellow wine and stir, obtain fingernail yellow wine soup C;
4), by the Allomyrinadichotoma adult of above-mentioned quality with boiled water scald and after death pulverize, must Allomyrinadichotoma D processed;
5), by medicinal liquid A, Exocarpium Gossypii wine liquid B, fingernail yellow wine soup C and vinegar Allomyrinadichotoma D mix, i.e. the medicine of obtained treatment primary thrombocytosis.
Embodiment 1 and embodiment 4 gained medicine are carried out clinical trial, and through overtesting, the drug effect of the medicine that embodiment 4 is obtained is better than embodiment 1, and result of the test is in table two.
Table two
| Embodiment 1 | Take medicine and have 3 courses for the treatment of Platelet of 65% obviously to reduce, symptom alleviates | Take medicine and have 6 courses for the treatment of Platelet of 68% normal, transference cure, 10% platelet declines, and symptom alleviates, and all the other are not improved | Have the patient of 70% after the normal patient's drug withdrawal of platelet, the interval time that platelet rises again was more than two months |
| Embodiment 4 | Take medicine and have 3 courses for the treatment of Platelet of 70% obviously to reduce, symptom alleviates | Take medicine and have 6 courses for the treatment of Platelet of 78% obviously to reduce, symptom alleviates, and 7% platelet declines, and symptom alleviates, and all the other are not improved | Have the patient of 75% after the normal patient's drug withdrawal of platelet, the interval time that platelet rises again was more than 70 days |
Medicine of the present invention is after above-mentioned technique is prepared, particularly Herba Mimosae Pudicae, Herba Lycopodii, Caulis Akebiae, Herba Ecliptae, the white palm, youth-and-old-age, Aspongopus, Galla Chinensis, Semen Lini, Rhizoma Cimicifugae, Stalactitum, the Radix Pulsatillae, Radix Sanguisorbae, be heated to boiling, slow fire boiling 10-20 minute, then add the Radix et Caulis Opuntiae Dillenii of above-mentioned weight simultaneously, Herba Artemisiae Annuae decocts 10-20 minute, the Flos Epiphylli Oxypetali intense fire finally adding above-mentioned weight decocts 5 minutes, the curative effect of medicine has had significant raising, when other conditions are identical, the interval time that platelet rises again rose to 70 days by two months, the normal patient of platelet after 6 courses for the treatment of that takes medicine rises to 78% by 68%.
Embodiment 5, treat a medicine for primary thrombocytosis, be made up of the crude drug of following weight: Concha 1.5g, Exocarpium Gossypii 8g, Herba Mimosae Pudicae 1.5g, Herba Lycopodii 3g, Caulis Akebiae 4g, Herba Ecliptae 3g, Radix et Caulis Opuntiae Dillenii 6g, slap 4g, Flos Epiphylli Oxypetali 6g, youth-and-old-age 5g, Aspongopus 1.5g, Allomyrinadichotoma 4g, Galla Chinensis 4g, Semen Lini 3g, Herba Artemisiae Annuae 5g, Rhizoma Cimicifugae 3g, Stalactitum 3g, Radix Pulsatillae 3g, Radix Sanguisorbae 4g in vain.
A kind of preparation method for the treatment of the medicine of primary thrombocytosis comprises the following steps:
1) Herba Mimosae Pudicae of above-mentioned weight, Herba Lycopodii, Caulis Akebiae, Herba Ecliptae, the white palm, youth-and-old-age, Aspongopus, Galla Chinensis, Semen Lini, Rhizoma Cimicifugae, Stalactitum, the Radix Pulsatillae, Radix Sanguisorbae, is got, be heated to boiling, slow fire boiling 10-20 minute, then add the Radix et Caulis Opuntiae Dillenii of above-mentioned weight simultaneously, Herba Artemisiae Annuae decocts 10-20 minute, the Flos Epiphylli Oxypetali intense fire finally adding above-mentioned weight decocts 5 minutes; Leach to obtain medicinal liquid A;
2), Exocarpium Gossypii is added the yellow wine of Exocarpium Gossypii weight 3 times of weight; Decoct, continue to decoct 5-10 minute after keeping boiling; Obtain Exocarpium Gossypii wine liquid B;
3), by the Concha of above-mentioned quality burn till carbon shape and wear into fine powder, add Concha 5 times of weight yellow wine and stir, obtain fingernail yellow wine soup C;
4), by the Allomyrinadichotoma adult of above-mentioned quality with boiled water scald after death to be placed on vinegar and steam 10-20 minute, then pulverize, obtain vinegar Allomyrinadichotoma D;
5), by medicinal liquid A, Exocarpium Gossypii wine liquid B, fingernail yellow wine soup C and vinegar Allomyrinadichotoma D mix, i.e. the medicine of obtained treatment primary thrombocytosis.
Embodiment 4 and embodiment 5 gained medicine are carried out clinical trial, and through overtesting, the drug effect of the medicine that embodiment 5 is obtained is better than embodiment 4, and result of the test is in table three.
Table three
| Embodiment 4 | Take medicine and have 3 courses for the treatment of Platelet of 65% obviously to reduce, symptom alleviates | Take medicine and have 6 courses for the treatment of Platelet of 68% normal, transference cure, 10% platelet declines, and symptom alleviates, and all the other are not improved | Have the patient of 70% after the normal patient's drug withdrawal of platelet, the interval time that platelet rises again was more than two months |
| Embodiment 5 | Take medicine and have 3 courses for the treatment of Platelet of 73% obviously to reduce, symptom alleviates | Take medicine and have 6 courses for the treatment of Platelet of 85% obviously to reduce, symptom alleviates, and 11% platelet declines, and symptom alleviates, and all the other are not improved | Have the patient of 85% after the normal patient's drug withdrawal of platelet, the interval time that platelet rises again was more than 3 months |
The Concha of above-mentioned quality is burnt till carbon shape and wear into adding of fine powder and vinegar Allomyrinadichotoma, significantly increase the curative effect of medicine, the patient that taking medicine has platelet normal 6 courses for the treatment of rises to 85% by 68%, when other conditions are identical, the interval time that platelet rises again rose to 70 days by two months.
Above-described embodiment 1-5, does not have myelosuppressive phenomenon to occur, does not affect bone marrow hematogenesis, and adopt busulfan and interferon-alpha long-term taking that bone marrow all can be caused seriously to suppress, affect the hemopoietic of bone marrow in drug administration process.
Claims (4)
1. treat a medicine for primary thrombocytosis, it is characterized in that: be made up of the crude drug of following weight: Concha 1-2g, Exocarpium Gossypii 5-10g, Herba Mimosae Pudicae 2-3g, Herba Lycopodii 2-4g, Caulis Akebiae 2-6g, Herba Ecliptae 2-4g, Radix et Caulis Opuntiae Dillenii 4-8g, slap 2-6g, Flos Epiphylli Oxypetali 4-8g, youth-and-old-age 3-6g, Aspongopus 1-2g, Allomyrinadichotoma 3-7g, Galla Chinensis 2-7g, Semen Lini 2-6g, Herba Artemisiae Annuae 3-8g, Rhizoma Cimicifugae 2-5g, Stalactitum 0.2-0.5g, Radix Pulsatillae 2-5g, Radix Sanguisorbae 3-5g in vain.
2. a kind of medicine for the treatment of primary thrombocytosis according to claim 1, is characterized in that: be made up of the crude drug of following weight: Concha 1.5g, Exocarpium Gossypii 8g, Herba Mimosae Pudicae 1.5g, Herba Lycopodii 3g, Caulis Akebiae 4g, Herba Ecliptae 3g, Radix et Caulis Opuntiae Dillenii 6g, slap 4g, Flos Epiphylli Oxypetali 6g, youth-and-old-age 5g, Aspongopus 1.5g, Allomyrinadichotoma 4g, Galla Chinensis 4g, Semen Lini 3g, Herba Artemisiae Annuae 5g, Rhizoma Cimicifugae 3g, Stalactitum 0.3g, Radix Pulsatillae 3g, Radix Sanguisorbae 4g in vain.
3. a kind of preparation method for the treatment of the medicine of primary thrombocytosis according to claim 2, comprises the following steps: it is characterized in that:
1) Herba Mimosae Pudicae of above-mentioned weight, Herba Lycopodii, Caulis Akebiae, Herba Ecliptae, the white palm, youth-and-old-age, Aspongopus, Galla Chinensis, Semen Lini, Rhizoma Cimicifugae, Stalactitum, the Radix Pulsatillae, Radix Sanguisorbae, is got, be heated to boiling, slow fire boiling 10-20 minute, then add the Radix et Caulis Opuntiae Dillenii of above-mentioned weight simultaneously, Herba Artemisiae Annuae decocts 10-20 minute, the Flos Epiphylli Oxypetali intense fire finally adding above-mentioned weight decocts 5 minutes; Leach to obtain medicinal liquid A;
2), Exocarpium Gossypii is added the yellow wine of Exocarpium Gossypii weight 3 times of weight; Decoct, continue to decoct 5-10 minute after keeping boiling; Obtain Exocarpium Gossypii wine liquid B;
3), by the Concha of above-mentioned quality burn till carbon shape and wear into fine powder, add Concha 5 times of weight yellow wine and stir, obtain fingernail yellow wine soup C;
4), by the Allomyrinadichotoma of above-mentioned quality be placed on vinegar and steam 10-20 minute, then pulverize, obtain vinegar Allomyrinadichotoma D;
5), by medicinal liquid A, Exocarpium Gossypii wine liquid B, fingernail yellow wine soup C and vinegar Allomyrinadichotoma D mix, i.e. the medicine of obtained treatment primary thrombocytosis.
4. a kind of preparation method for the treatment of the medicine of primary thrombocytosis according to claim 3, is characterized in that: described Allomyrinadichotoma scalds Allomyrinadichotoma adult after death for boiled water.
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| CN109793828A (en) * | 2019-03-27 | 2019-05-24 | 苏凤哲 | A kind of Chinese medicine composition and its preparation method and application for treating primary thrombocytosis |
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| CN109793828A (en) * | 2019-03-27 | 2019-05-24 | 苏凤哲 | A kind of Chinese medicine composition and its preparation method and application for treating primary thrombocytosis |
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