CN104491118A - Brain-tonifying and nerve-soothing beverage for alleviating brain traumas and preparation method thereof - Google Patents

Brain-tonifying and nerve-soothing beverage for alleviating brain traumas and preparation method thereof Download PDF

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CN104491118A
CN104491118A CN201410825959.9A CN201410825959A CN104491118A CN 104491118 A CN104491118 A CN 104491118A CN 201410825959 A CN201410825959 A CN 201410825959A CN 104491118 A CN104491118 A CN 104491118A
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parts
radix
drink
brain
pheretima
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王术茂
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王术茂
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    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
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    • A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/24—Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/41—Crassulaceae (Stonecrop family)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/52—Juglandaceae (Walnut family)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/17—Preparation or pretreatment of starting material involving drying, e.g. sun-drying or wilting
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention discloses a brain-tonifying and nerve-soothing beverage for alleviating brain traumas. The beverage is prepared from the following main raw materials in parts by weight: 9-15 parts of angelica dahurica, 6-12 parts of centella, 10-15 parts of kirilow rhodiola rhizome and roots, 5-10 parts of ossa draconis, 6-12 parts of apocynum venetum, 50-70 parts of semen juglandis, 5-15 parts of lucid ganoderma, 4.5-9 parts of longans, 5-15 parts of lumbricus, 2-5 parts of radix achyranthis bidentatae, 5-15 parts of salvia miltiorrhiza, 2-7 parts of cassia twig, 3-7 parts of deer-horn glue and 5-10 parts of olibanum. The brain-tonifying and nerve-soothing beverage disclosed by the invention is based on the principle of dialectical treatment of traditional Chinese medicine. The selected medicinal materials are used for relieving pain of symptom, tonifying brain and soothing the nerve and have the main effects of promoting circulation and removing stasis, clearing damp and eliminating swelling and tranquilizing and allaying excitement. In addition, the beverage further has the effects of reinforcing qi and nourishing blood, eliminating phlegm and calming wind, inducing resuscitation and restoring consciousness and the like and belongs to a medicine which considers inside and outside and is safe and effective. The beverage has an extremely good curative effect for brain traumas.

Description

Cerebral tonic tranquillizing drink alleviating brain wound and preparation method thereof
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of cerebral tonic tranquillizing drink alleviating brain wound and preparation method thereof.
Background technology
Cerebral trauma refers to cause due to foreign object, the macroscopic wound in brains portion, generally can cause serious consequence.Cerebral trauma often causes permanent disfunction in various degree.This depends primarily on infringement is in certain specific region (focal) of cerebral tissue or the infringement of popularity (dispersivity).The cerebral lesion of zones of different can cause different symptoms, and focal symptom comprises the symptoms such as motion, sensation, speech, vision, auditory abnormality.And DD often affects memory, sleeps or causes confusion and stupor.
The cause of disease: unexpected head accelerated motion, equally with head of fiercelying attack causes brain tissue impairment.The irremovable hard object of head fast ram or retarded motion suddenly are also common cerebral trauma reasons.The side be impacted or rightabout cerebral tissue and hard and the skull of projection collides time very easily sustain damage.Acceleration-deceleration damage is sometimes also referred to as offside blast injury.
Clinical manifestation 1. cerebral concussion syndrome: occur of short duration loss of consciousness after cerebral concussion, recovers in general 30 minutes.After waking up, patient is to a moment before injured scene and wound, situation can not be recalled.Patient can have headache, vomiting, dizzy, irritability, and emotional lability is self-doubt, distractibility, and vegetative nerve symptom is as palor, and cold sweat, blood pressure drops, pulse is slow, hypopnea etc.2. the caused stupor of cerebral trauma: the stupor that duration differs can occur craniocerebral injury, stupor is to recovering clear-headed process, and can there be lethargy centre, muddy, delirium etc.Heavily in undulatory property time light during disturbance of consciousness.3. delirium caused by cerebral trauma: delirium is generally by go into a coma or lethargy transfers.Occupational characteristic before the behavior reflection of some patient when delirium is sick.Many patients show opposing, noisy, uncooperative, and other are more aggressive.Can have phobic photis, serious patient can have confusion excited, the behavior of even strong impulse sexual violence.Delirium can replace by illiteracy other disturbance of consciousnesss such as XML-Feed-JS-Feed and oneiroid state.4. amnestic syndrome caused by cerebral trauma: its most outstanding feature forgets fabricating on basis, the normal irritability of patient.Its Duration Ratio alcoholic-toxic amnestic syndrome is short.5. subdural hematoma caused by cerebral trauma: can occur very soon after injured, most headache and drowsiness.Excited with delirious mobility once in a while, about half patient has papilloedema.The feature of chronic subdural hematoma is drowsiness, blunt, hypomnesis, and generalized dementia symptom appears in severe patient, and some patients's cerebrospinal pressure slightly raises, and protein quantification increases, and outward appearance is in yellow.
Alleviate in the technology of brain wound in existing traditional Chinese medicine field, the patent document of Authorization Notice No. CN 102631579 B (application number 201210113893.1) discloses a kind of oral traditional Chinese medicine preparation for the treatment of postcerebral injury syndrome, it is characterized in that adopting the raw material of Chinese medicine of following weight parts to make: the Radix Astragali 10 ± 2, Radix Panacis Quinquefolii 10 ± 2, Radix Angelicae Sinensis 10 ± 2, Fructus Lycii 10 ± 2, Radix Salviae Miltiorrhizae 10 ± 2, Ganoderma 10 ± 2, Radix Paeoniae Rubra 10 ± 2, Semen Persicae 10 ± 2, Poria 10 ± 2, Pericarpium Citri Reticulatae 10 ± 2, Semen Plantaginis 10 ± 2, Concretio Silicea Bambusae 10 ± 2, Rhizoma Acori Graminei 10 ± 2, Rhizoma Gastrodiae 10 ± 2, Ramulus Uncariae Cum Uncis 10 ± 2, Semen Ziziphi Spinosae 10 ± 2, Succinum powder 10 ± 2, process Rhizoma Rhodiolae kirilowii 6 ± 1.2.The Chinese patent of Authorization Notice No. CN 103007089 B (application number 201310009705.5) disclose a kind of treat craniocerebral trauma after the Chinese medicine composition of concurrent stress ulcer, it is characterized in that, this Chinese medicine composition is
Be made up of the medicine of following weight portion: Radix Cirsii Japonici 10-20 part, Herba Cirsii 10-20 part, charred Petiolus Trachycarpi 10-20 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 25-35 part, Radix Et Rhizoma Rhei 4-14 part, Radix Notoginseng powder 3-9 part, Semen Juglandis 25-35 part and Herba Agrimoniae 25-35 part.
As can be seen here, Chinese medicine obtains good curative effect improving in cerebral trauma, but in existing patent, operation trouble is refined in processing, and cost is higher, is not suitable for poor family and uses.
Summary of the invention
For the deficiency of existing alleviation brain wound present situation, an object of the present invention is to provide the cerebral tonic tranquillizing alleviating brain wound drink, there is easy to operate, evident in efficacy, sufferer and bear painful little feature, and its adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned alleviation brain wound cerebral tonic tranquillizing drink.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Alleviate the cerebral tonic tranquillizing drink of brain wound, take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 9-15 part, Herba Centellae 6-12 part, Rhizoma Rhodiolae kirilowii 10-15 part, Os Draconis 5-10 part, Herba Apocyni veneti 6-12 part, Semen Juglandis 50-70 part, Ganoderma 5-15 part, Arillus Longan 4.5-9 part, Pheretima 5-15 part, Radix Achyranthis Bidentatae 2-5 part, Radix Salviae Miltiorrhizae 5-15 part, Ramulus Cinnamomi 2-7 part, Colla cornus cervi 3-7 part, Olibanum 5-10 part.
The cerebral tonic tranquillizing drink of above-mentioned alleviation brain wound, takes off the primary raw material stating weight proportion and is prepared from: Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 10-12 part, Herba Centellae 7-10 part, Rhizoma Rhodiolae kirilowii 11-14 part, Os Draconis 6-9 part, Herba Apocyni veneti 9-11 part, Semen Juglandis 55-65 part, Ganoderma 8-11 part, Arillus Longan 5-8 part, Pheretima 7-12 part, Radix Achyranthis Bidentatae 3-4 part, Radix Salviae Miltiorrhizae 7-12 part, Ramulus Cinnamomi 3-6 part, Colla cornus cervi 4-6 part, Olibanum 6-9 part.
The cerebral tonic tranquillizing drink of above-mentioned alleviation brain wound, takes off the primary raw material stating weight proportion and is prepared from: Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 10 parts, Herba Centellae 8 parts, Rhizoma Rhodiolae kirilowii 12 parts, Os Draconis 8 parts, Herba Apocyni veneti 10 parts, Semen Juglandis 60 parts, Ganoderma 10 parts, Arillus Longan 6.5 parts, Pheretima 10 parts, Radix Achyranthis Bidentatae 3.5 parts, Radix Salviae Miltiorrhizae 10 parts, Ramulus Cinnamomi 5 parts, Colla cornus cervi 5 parts, Olibanum 7 parts.
Alleviate the preparation method of the cerebral tonic tranquillizing drink of brain wound, specifically have following steps to be prepared from:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 60-100 mesh sieve stand-by;
2. be divided into two by Pheretima, clean, with the slightly vexed 10-20 minute of Chinese liquor, be placed in the hot pot that dryouies, repeatedly stir-fry to crisp, it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla cornus cervi is added after big fire is boiled, the Radix Angelicae Dahuricae (Radix Heraclei Scabridi) of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Olibanum is added after Colla cornus cervi melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 60-90 minute, sealing and standing 3-5 hour, get supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 80-120 mesh sieve;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, dry heat sterilization 3-8 minute at 120-140 DEG C, is sealed in after cooling in plastic bottle, obtain cerebral tonic tranquillizing drink.
The preparation method of above-mentioned cerebral tonic tranquillizing drink, preparation process 1. smalls crosses 70-90 mesh sieve stand-by (preferred, it is stand-by that smalls crosses 80 mesh sieves).
The preparation method of above-mentioned cerebral tonic tranquillizing drink, the consumption of preparation process 2. Chinese liquor be the 1-3 of Pheretima weight doubly (preferred, the consumption of Chinese liquor be the 1.5-2.5 of Pheretima weight doubly, be more preferably, the consumption of Chinese liquor is 2 times of Pheretima weight).
The preparation method of above-mentioned cerebral tonic tranquillizing drink, preparation process is 2. with slightly vexed 13-18 minute of Chinese liquor (preferred, with Chinese liquor slightly vexed 15 minutes).
The preparation method of above-mentioned cerebral tonic tranquillizing drink, 3. preparation process turns slow fire boiling 70-80 minute, sealing and standing 3.5-4.5 hour (preferred, to turn slow fire boiling 75 minutes, sealing and standing 4 hours).
The preparation method of above-mentioned cerebral tonic tranquillizing drink, preparation process 5. at 125-135 DEG C dry heat sterilization 5-7 minute (preferred, dry heat sterilization 6 minutes at 130 DEG C).
Using method: 3 times on the one, get cerebral tonic tranquillizing of the present invention drink 10-20ml, 10 days be a course for the treatment of at every turn.
This cerebral tonic tranquillizing drink, to alleviation brain wound Be very effective, has pain relieving, supplementing the brain, calms the nerves, controls dizzy effect.
The pharmacological effect of each crude drug is respectively:
Radix Angelicae Dahuricae (Radix Heraclei Scabridi): base is former: be the root of Umbelliferae archangel Angelica dahurica.Composition: root is containing Coumarins: gloomy Byakangelicol, 7-demethyl cork Pericarpium Zanthoxyli, Byakangelicol, byak-angelicin, imperatorin, different imperatorin, oxypeucedanin, phellopterin etc.The property of medicine: pungent, bitter, temperature.Function cures mainly: expelling pathogenic wind from the body surface, removing damp and stopping pain.Cure mainly flu, headache, toothache, rheumatic arthralgia.
Herba Centellae: base is former: be dry herb or the whole herb with root of dicotyledon Umbelliferae Herba Centellae.Composition: containing the Triterpenoid of multiple α-balsam alcohol type, wherein have asiaticoside, thankuniside, isothankuniside, asiaticoside, Brahmoside, broken hot rice glycosides and Brahmic acid etc., and madasiatic acid.The property of medicine: bitter, acrid, cold.Return liver,spleen,kidney warp.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Be the long-lived medicine of Asians, can refresh oneself by beneficial brain.Research shows to have nourishing, antiinflammatory, healing of wound, diuresis relieving constipation and calm effect.Also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity, because it can stimulate the replacement of deep skin cell.It is neural nourishing agent, can improve memory, alleviate mental fatigue; Also can blood pressure lowering, treatment hepatopathy etc.
Rhizoma Rhodiolae kirilowii: base is former: be the root and rhizome of Crassulaceae Rhodida plant Rhodiola kirilowii (Regel) Maxim..Composition: herb is containing butyl alcohol, and daucosterol, rhodioside, hundred arteries and veins are with glycosides.The property of medicine: bitter, puckery, temperature.Return lung, the heart, liver, large intestine channel.Function cures mainly: tranquilizing by nourishing the heart, blood stasis dispelling, hemostasis.Cure mainly deficiency of vital energy and physically weak, weak palpitation and insomnia of losing heart, dizzy dizzy, pain uncomfortable in chest, traumatic injury, menoxenia, metrorrhagia, spits blood, dysentery, diarrhoea.
Os Draconis: base is former: for mammal in ancient times resembles the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex, bovine, deer class etc.Composition: Os Draconis, mainly containing calcium carbonate and calcium phosphate, still contain ferrum, potassium, sodium, chlorine, sulfate radical etc.The property of medicine: puckery, sweet, flat.GUIXIN, liver, kidney, large intestine channel.Function cures mainly: tranquilizing mind, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly cardiopalmus, seized with terror swollen, insomnia, forgetful, infantile convulsion, demented, dizzy, spontaneous sweating, the seminal emission enuresis, bleeding not during menses, chronic diarrhea and dysentery, ulcer does not close up and eczema for a long time.
Herba Apocyni veneti: base is former: be the leaf of Apocynaceae Apocynum plant Herba Apocyni veneti.Composition: leaf contains Quercetin, isoquercitrin, hyperin, Trifolin, cloud English glycosides, rutin, cianidanol, anthraquinone, and the several amino acids such as glutamic acid, alanine.The property of medicine: sweet, micro-hardship, cool.Function cures mainly: heat clearing away, and suppressing the hyperactive liver is calmed the nerves, diuretic.Cure mainly high blood Os Draconis pressure sick, dizzy, headache, cardiopalmus, insomnia, edema oliguria.
Semen Juglandis: brain-strengthening is anti-old: Semen Juglandis contains more protein and the required unsaturated fatty acid of human nutrition, and these compositions are all the important substance of cerebral tissue cellular metabolism, can nursing brain cells, cerebral function improvement.To releive fatigue, resistance to compression.
Ganoderma: Ganoderma profile is umbrella, cap kidney shape, semicircle or subcircular are the sporophore of On Polyporaceae Ganoderma.There is effect of invigorating QI and tranquilization, relieving cough and asthma, for dizzy sleeplessness, shortness of breath and palpitation, asthenia cough with asthma.Malaise, insomnia, palpitation with fear.This product sweet in the mouth is put down, and enters heart channel, can reinforcing the heart blood, the beneficial motive, tranquilizing mind, therefore availablely controls the disease such as malaise caused by insufficiency of vital energy and blood, lack of preservation of spirit, insomnia, palpitation with fear, dreaminess, forgetful, the tired Mental fatigue of body, lack of appetite.
Arillus Longan: reinforcing the heart spleen, replenishing QI and blood, strengthening the spleen and stomach, supports muscle.Worry impairing spleen, dizzy, insomnia, severe palpitation, emptyly wins, and after being ill or puerperal asthenia, and to lose blood disease due to insufficiency of the spleen caused hematochezia.Modem medical practices proves, it also has effect of beauty treatment, life lengthening.
Pheretima: calentura mania and irritation, infantile convulsion, cough with asthma, headache conjunctival congestion, laryngopharynx swelling and pain, urinary obstruction, Fengshi Guanjie pain, hemiplegia LUMBRICUS is dry waits disease.External is coated with the disease such as erysipelas, dermatitis rhus.1. clearing heat for calming endogenous wind: cure mainly high fever infantile convulsion, wind symptom is twitched.2. lung-clearing asthma-relieving: the asthma of lung-heat productive cough can be controlled, better to lung heat type bronchial asthma curative effect.3. inducing diuresis for treating stranguria syndrome: be applicable to damp invasion of lower energizer, the puckery pain of pyretic stranguria.4. current meridians: available pyretic arthralgia of controlling saves swollen swelling pain; Suitable compatibility also can control arthralgia due to cold; Compatibility replenishing qi and promoting blood flow medicine is usually used in blood stasis due to qi deficiency, and meridians are unfavorable, aphasia hemiplegia person.
Radix Achyranthis Bidentatae: Radix Achyranthis is used as medicine, raw use, promoting blood circulation to restore menstrual flow; Control puerperal abdonimal pain, menoxenia, amenorrhea, epistaxis toothache caused by fire of deficiency type, beriberi edema; Ripe use, invigorating the liver and kidney, strong waist knee joint; Control soreness of waist and knee joint, caused by liver and kidney deficiency, traumatic injury stasis of blood pain.Veterinary, as controlling cattle weak foot disease, gets injured by a fall knochenbruch etc.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, are slightly cold.GUIXIN, Liver Channel.There is stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, the effect of the relieving restlessness that clears away heart-fire.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Ramulus Cinnamomi: acrid, sweet, warm.GUIXIN, lung, urinary bladder channel.There is diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, effect of the flat gas that spins.Be usually used in anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus etc.
Colla cornus cervi: temperature compensation Liver and kidney, beneficial intensive culture blood.Dizzy for blood deficiency, the acid of waist knee joint is cold, and asthenia is become thin.
Olibanum: this product has more significant analgesic activity, headed by Olibanum, the uterus ball of taste medicine antibacterially have stronger bacteriostasis than multiple, and effectively can kill infusorian, regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
The principle of disease treatment debated by cerebral tonic tranquillizing drink of the present invention based on Chinese medicine.The medical material selected has for showing disease pain relieving, supplementing the brain, calming the nerves, and Main Function is blood circulation promoting and blood stasis dispelling, damp eliminating detumescence, tranquillizing and allaying excitement; Still there are benefiting QI and nourishing blood, eliminating phlegm and calming wind and the effects such as logical brain of having one's ideas straightened out in addition, take into account inside and outside belonging to and medicine safely and effectively, have fabulous therapeutical effect to alleviation brain wound.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 alleviates the cerebral tonic tranquillizing drink of brain wound, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 9 parts, Herba Centellae 6 parts, Rhizoma Rhodiolae kirilowii 10 parts, Os Draconis 5 parts, Herba Apocyni veneti 6 parts, Semen Juglandis 50 parts, Ganoderma 5 parts, Arillus Longan 4.5 parts, Pheretima 5 parts, Radix Achyranthis Bidentatae 2 parts, Radix Salviae Miltiorrhizae 5 parts, Ramulus Cinnamomi 2 parts, Colla cornus cervi 3 parts, Olibanum 5 parts.
The preparation method of the cerebral tonic tranquillizing drink of above-mentioned alleviation brain wound, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 60 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 10 minutes, the consumption of Chinese liquor is 1 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla cornus cervi is added after big fire is boiled, the Radix Angelicae Dahuricae (Radix Heraclei Scabridi) of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Olibanum is added after Colla cornus cervi melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 60 minutes, sealing and standing 3 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 80 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 120 DEG C, dry heat sterilization 3 minutes, is sealed in after cooling in plastic bottle, obtain cerebral tonic tranquillizing drink.
Model case one Zhu XX, man, 42 years old, Dezhou, Shandong Province personage, knocked into the back by another motorcycle by motorcycle and founder left brain, companion is hemorrhage for left volume temporal lobe extensive brain contusion, and Post operation occurs a large amount of hematemesis, in cerise in one week, and mixing with food residue, be mixed with gastric juice, vomitus test strong positive, doctor just suggestion drinks cerebral tonic tranquillizing of the present invention drink.
Drink the cerebral tonic tranquillizing drink of embodiment 1 gained, drink 1 day, malaise symptoms alleviates to some extent, and pain alleviates to some extent, continues to drink 4 days, and malaise symptoms disappears substantially, continues to take 4 weeks, removes examination in hospital, and self-induction is fully recovered.
Embodiment 2 alleviates the cerebral tonic tranquillizing drink of brain wound, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 15 parts, Herba Centellae 12 parts, Rhizoma Rhodiolae kirilowii 15 parts, Os Draconis 10 parts, Herba Apocyni veneti 12 parts, Semen Juglandis 70 parts, Ganoderma 15 parts, Arillus Longan 9 parts, Pheretima 15 parts, Radix Achyranthis Bidentatae 5 parts, Radix Salviae Miltiorrhizae 15 parts, Ramulus Cinnamomi 7 parts, Colla cornus cervi 7 parts, Olibanum 10 parts.
The preparation method of the cerebral tonic tranquillizing drink of above-mentioned alleviation brain wound, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 100 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 20 minutes, the consumption of Chinese liquor is 3 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla cornus cervi is added after big fire is boiled, the Radix Angelicae Dahuricae (Radix Heraclei Scabridi) of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Olibanum is added after Colla cornus cervi melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 90 minutes, sealing and standing 5 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 120 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 140 DEG C, dry heat sterilization 8 minutes, is sealed in after cooling in plastic bottle, obtain cerebral tonic tranquillizing drink.
Embodiment 3 alleviates the cerebral tonic tranquillizing drink of brain wound, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 10 parts, Herba Centellae 7 parts, Rhizoma Rhodiolae kirilowii 11 parts, Os Draconis 6 parts, Herba Apocyni veneti 9 parts, Semen Juglandis 55 parts, Ganoderma 8 parts, Arillus Longan 5 parts, Pheretima 7 parts, Radix Achyranthis Bidentatae 3 parts, Radix Salviae Miltiorrhizae 7 parts, Ramulus Cinnamomi 3 parts, Colla cornus cervi 4 parts, Olibanum 6 parts.
The preparation method of the cerebral tonic tranquillizing drink of above-mentioned alleviation brain wound, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 70 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 13 minutes, the consumption of Chinese liquor is 1.5 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla cornus cervi is added after big fire is boiled, the Radix Angelicae Dahuricae (Radix Heraclei Scabridi) of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Olibanum is added after Colla cornus cervi melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 70 minutes, sealing and standing 3.5 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 90 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 125 DEG C, dry heat sterilization 5 minutes, is sealed in after cooling in plastic bottle, obtain cerebral tonic tranquillizing drink.
Embodiment 4 alleviates the cerebral tonic tranquillizing drink of brain wound, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 12 parts, Herba Centellae 10 parts, Rhizoma Rhodiolae kirilowii 14 parts, Os Draconis 9 parts, Herba Apocyni veneti 11 parts, Semen Juglandis 65 parts, Ganoderma 11 parts, Arillus Longan 8 parts, Pheretima 12 parts, Radix Achyranthis Bidentatae 4 parts, Radix Salviae Miltiorrhizae 12 parts, Ramulus Cinnamomi 6 parts, Colla cornus cervi 6 parts, Olibanum 9 parts.
The preparation method of the cerebral tonic tranquillizing drink of above-mentioned alleviation brain wound, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 90 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 18 minutes, the consumption of Chinese liquor is 2.5 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla cornus cervi is added after big fire is boiled, the Radix Angelicae Dahuricae (Radix Heraclei Scabridi) of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Olibanum is added after Colla cornus cervi melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 80 minutes, sealing and standing 4 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 110 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 135 DEG C, dry heat sterilization 7 minutes, is sealed in after cooling in plastic bottle, obtain cerebral tonic tranquillizing drink.
Model case two: ancient sacrificial utensil XX, female, 60 years old, Jinan, Shandong Province personage.Carry out Craniotomy evacuation of hematoma after traffic accident, after clear-headed, occur epigastric discomfort, mild pain and tenderness, feel sick, a small amount of vomiting liquid be kermesinus thus doctor advised its drink gained cerebral tonic tranquillizing of the present invention and drink.
Drink the cerebral tonic tranquillizing drink of embodiment 4 gained, take 5 days, pain relief, sleep quality very good; Drink 20 days, malaise symptoms disappears substantially; Continue to drink 1 month, drug withdrawal is not recurred so far.
Embodiment 5 alleviates the cerebral tonic tranquillizing drink of brain wound, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 10 parts, Herba Centellae 8 parts, Rhizoma Rhodiolae kirilowii 12 parts, Os Draconis 8 parts, Herba Apocyni veneti 10 parts, Semen Juglandis 60 parts, Ganoderma 10 parts, Arillus Longan 6.5 parts, Pheretima 10 parts, Radix Achyranthis Bidentatae 3.5 parts, Radix Salviae Miltiorrhizae 10 parts, Ramulus Cinnamomi 5 parts, Colla cornus cervi 5 parts, Olibanum 7 parts.
The preparation method of the cerebral tonic tranquillizing drink of above-mentioned alleviation brain wound, step is as follows:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 80 mesh sieves stand-by;
2. be divided into two by Pheretima, clean, with Chinese liquor slightly vexed 15 minutes, the consumption of Chinese liquor is 2 times of Pheretima weight, is placed in the hot pot that dryouies, repeatedly stir-fries to crisp, and it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla cornus cervi is added after big fire is boiled, the Radix Angelicae Dahuricae (Radix Heraclei Scabridi) of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Olibanum is added after Colla cornus cervi melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 75 minutes, sealing and standing 4 hours, gets supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 100 mesh sieves;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, at 130 DEG C, dry heat sterilization 6 minutes, is sealed in after cooling in plastic bottle, obtain cerebral tonic tranquillizing drink.
Test example: embodiment 5 gained alleviates the clinical practice of the cerebral tonic tranquillizing drink of brain wound: in June, 2008 in December ,-2011, screen 200 routine patients in 4 hospitals, wherein women 100 example, male 100 example, oldest 72 years old, minimal ages 40 years old, 55 years old mean age.Before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 products obtained therefrom, matched group takes other medicine, the criterion of curative effect situation: cure: after drinking of said product, and malaise symptoms disappears; Effective: after drinking of said product, malaise symptoms alleviates or partial disappearance; Invalid: a course for the treatment of of drinking of said product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1: take embodiment 5 product 40-72 year alleviate brain traumatic patient therapeutic outcome
Therapeutic effect: cure 85 examples (85%), effective 10 examples (10%), invalid 5 examples (5%), total effective rate 95%.Successful is better than matched group.

Claims (9)

1. alleviate the cerebral tonic tranquillizing drink of brain wound, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 9-15 part, Herba Centellae 6-12 part, Rhizoma Rhodiolae kirilowii 10-15 part, Os Draconis 5-10 part, Herba Apocyni veneti 6-12 part, Semen Juglandis 50-70 part, Ganoderma 5-15 part, Arillus Longan 4.5-9 part, Pheretima 5-15 part, Radix Achyranthis Bidentatae 2-5 part, Radix Salviae Miltiorrhizae 5-15 part, Ramulus Cinnamomi 2-7 part, Colla cornus cervi 3-7 part, Olibanum 5-10 part.
2. the cerebral tonic tranquillizing drink of alleviation brain wound according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 10-12 part, Herba Centellae 7-10 part, Rhizoma Rhodiolae kirilowii 11-14 part, Os Draconis 6-9 part, Herba Apocyni veneti 9-11 part, Semen Juglandis 55-65 part, Ganoderma 8-11 part, Arillus Longan 5-8 part, Pheretima 7-12 part, Radix Achyranthis Bidentatae 3-4 part, Radix Salviae Miltiorrhizae 7-12 part, Ramulus Cinnamomi 3-6 part, Colla cornus cervi 4-6 part, Olibanum 6-9 part.
3. the cerebral tonic tranquillizing drink of alleviation brain wound according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 10 parts, Herba Centellae 8 parts, Rhizoma Rhodiolae kirilowii 12 parts, Os Draconis 8 parts, Herba Apocyni veneti 10 parts, Semen Juglandis 60 parts, Ganoderma 10 parts, Arillus Longan 6.5 parts, Pheretima 10 parts, Radix Achyranthis Bidentatae 3.5 parts, Radix Salviae Miltiorrhizae 10 parts, Ramulus Cinnamomi 5 parts, Colla cornus cervi 5 parts, Olibanum 7 parts.
4. the preparation method of the cerebral tonic tranquillizing drink of the alleviation brain wound according to any one of claim 1-3, is characterized in that: specifically have following steps to be prepared from:
1. Os Draconis are smashed, be placed on smokeless stove fire, burn and make the carbonization of medical surfaces part to outside burned black for spending, then grind to form smalls, cross 60-100 mesh sieve stand-by;
2. be divided into two by Pheretima, clean, with the slightly vexed 10-20 minute of Chinese liquor, be placed in the hot pot that dryouies, repeatedly stir-fry to crisp, it is stand-by to grind to form smalls;
3. clear water is placed in marmite, Colla cornus cervi is added after big fire is boiled, the Radix Angelicae Dahuricae (Radix Heraclei Scabridi) of clean chopping, Herba Centellae, Rhizoma Rhodiolae kirilowii, Herba Apocyni veneti, Ganoderma, Arillus Longan, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Ramulus Cinnamomi and Olibanum is added after Colla cornus cervi melts completely, while stir infusion on one side with large ferrum spoon, add after filtrate is boiled step 1. with step 2. gained smalls, after intense fire is fried open, cover seal cover, turn slow fire boiling 60-90 minute, sealing and standing 3-5 hour, get supernatant stand-by;
4. Semen Juglandis is placed in and burns on hot clean iron plate, when Semen Juglandis is dried to crisp, grind to form smalls, cross 80-120 mesh sieve;
5. by step 3. gained supernatant add step 4. gained walnut powder after being heated to 80 DEG C, until boiling after 10 minutes, dry heat sterilization 3-8 minute at 120-140 DEG C, is sealed in after cooling in plastic bottle, obtain cerebral tonic tranquillizing drink.
5. the preparation method of cerebral tonic tranquillizing drink according to claim 4, is characterized in that: step 1. smalls crosses 70-90 mesh sieve stand-by (preferred, it is stand-by that smalls crosses 80 mesh sieves).
6. the preparation method of cerebral tonic tranquillizing drink according to claim 4, it is characterized in that: the consumption of step 2. Chinese liquor is that the 1-3 of Pheretima weight is doubly (preferred, the consumption of Chinese liquor is 1.5-2.5 times of Pheretima weight, and be more preferably, the consumption of Chinese liquor is 2 times of Pheretima weight).
7. the preparation method of cerebral tonic tranquillizing according to claim 4 drink, is characterized in that: step is 2. with slightly vexed 13-18 minute of Chinese liquor (preferred, with Chinese liquor slightly vexed 15 minutes).
8. the preparation method of cerebral tonic tranquillizing drink according to claim 4, is characterized in that: 3. step turns slow fire boiling 70-80 minute, sealing and standing 3.5-4.5 hour (preferred, to turn slow fire boiling 75 minutes, sealing and standing 4 hours).
9. the preparation method of cerebral tonic tranquillizing drink according to claim 4, is characterized in that: step 5. at 125-135 DEG C dry heat sterilization 5-7 minute (preferred, dry heat sterilization 6 minutes at 130 DEG C).
CN201410825959.9A 2014-12-26 2014-12-26 Brain-tonifying and nerve-soothing beverage for alleviating brain traumas and preparation method thereof Pending CN104491118A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103007089A (en) * 2013-01-11 2013-04-03 牟淑善 Traditional Chinese medicine composition for treating post-craniocerebral trauma stress ulcer
CN103386080A (en) * 2013-07-08 2013-11-13 张秀菊 Medicine composite for curing combined external head injuries in clinical nursing

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103007089A (en) * 2013-01-11 2013-04-03 牟淑善 Traditional Chinese medicine composition for treating post-craniocerebral trauma stress ulcer
CN103386080A (en) * 2013-07-08 2013-11-13 张秀菊 Medicine composite for curing combined external head injuries in clinical nursing

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