CN104474347A - Health capsule for treating reflux esophagitis caused by gastroduodenal dysfunction and preparation method of health capsule - Google Patents

Health capsule for treating reflux esophagitis caused by gastroduodenal dysfunction and preparation method of health capsule Download PDF

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CN104474347A
CN104474347A CN201410773466.5A CN201410773466A CN104474347A CN 104474347 A CN104474347 A CN 104474347A CN 201410773466 A CN201410773466 A CN 201410773466A CN 104474347 A CN104474347 A CN 104474347A
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fructus
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health
semen
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张忠
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JINAN FANGYU CULTURE MEDIA Co Ltd
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JINAN FANGYU CULTURE MEDIA Co Ltd
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Abstract

The invention discloses a health capsule for treating reflux esophagitis caused by gastroduodenal dysfunction. The health capsule comprises the following active pharmaceutical ingredients in parts by weight: 5-15 parts of immature bitter orange, 6-12 parts of rhizoma polygoni paleacei, 12-25 parts of corn, 8-16 parts of pumpkin, 6-12 parts of ark shell, 5-15 parts of radish seeds, 3-7 parts of fossilizid, 7-15 parts of sea-buckthorn, 10-20 parts of black sesame, 3-9 parts of walnut kernels, 9-15 parts of diverse wormwood herb, 5-15 parts of largehead atractylodes rhizome, 3-12 parts of myrrh, 3-8 parts of guava and 10-20 parts of bamboo shavings. The health capsule disclosed by the invention has the advantages of scientific formula of traditional Chinese medicine particles and rapid onset of action, and can fundamentally cure reflux esophagitis caused by gastroduodenal dysfunction; and furthermore, the health capsule is simple in preparation method, convenient to take and convenient to carry.

Description

The health-caring capsule its preparation method of the reflux esophagitis that treatment gastroduodenal malfunction causes
Technical field
The invention discloses a kind of health-caring capsule its preparation method for the treatment of the reflux esophagitis that gastroduodenal malfunction causes, belong to Chinese medicine and field of health care products.
Background technology
Reflux esophagitis (RE) enters by Stomach duodenum content reflux the esophagitis sexually transmitted disease (STD) that esophagus causes to become, and Endoscopic Features is the breakage of Esophageal Mucosa, i.e. rotten to the corn the and (or) esophageal ulcer of esophagus.Reflux esophagitis can betide the crowd at any age, and Adult Onset leads and increases with the age and raise.Hesperian sickness rate is high, and Asia sickness rate is low.This geographic difference may be relevant with h and E factor.But the sickness rate in the recent two decades whole world is all on the rise.Middle-aged and elderly people, obesity, smoking, to drink and stress is greatly the group of people at high risk of reflux esophagitis.
The cause of disease: the 1. destruction of anti-reflux barrier: lower esophageal sphincter (LES) is the higher-pressure region on esophagus and stomach boundary line within the scope of 3 ~ 5cm.This place's rest pressure is 15 ~ 30mmHg, forms a pressure barrier, plays the physiological action preventing gastric content reflux from entering esophagus.Normal person's intra-abdominal pressure increases and causes LES contraction reflection by vagus nerve, and LES is pressed into doubly to be increased in case GER.LES can not cause strong LES contractile response person when pressing through low and intra-abdominal pressure increase, then can cause GER.Cholinergic and beta-adrenergic agonist medicine, alpha-adrenergic antagonistic, dopamine, stable, Calcilytic, morphine and fat, ethanol, caffeine and smoking etc. are multiple all can affect LES function with food factor, brings out GER.In addition, trimester of pregnancy, oral containing Progesterone contraceptive phase and menstrual cycle later stage, blood plasma progesterone levels increases, the incidence rate also corresponding increase of GER.2. esophageal acid cleans up the obstacle of function: normal esophageal acid is cleaned up function and comprised in the emptying and saliva of esophagus and two parts.When acidic gastric contents thing reflux, 1 ~ 2 (10 ~ 15 seconds) secondary esophageal peristalsis is only needed to get final product emptying nearly all reflux thing.Residue in a small amount of acid solution in Esophageal Mucosa lacuna then can by saliva (normal person is per hour 1000 ~ 1500ml, pH be 6 ~ 8 saliva enter stomach through esophagus) neutralization.The function that esophageal acid is cleaned up is that minimizing Esophageal Mucosa is soaked in the time limit in gastric acid, therefore has the effect preventing reflux esophagitis.During nighttime sleep, salivation almost stops, and secondary esophageal peristalsis is also rare generation, and the esophageal acid at night cleans up obvious delay, thus night GER harm even more serious.3. the infringement of Esophageal Mucosa anti-reflux barrier function: when defensive barrier damaged, even if also can cause esophagitis in normal reflux situation.Research finds, the weakening of epitheliosis of esophageal cells and repair ability is one of major reason of reflux esophagitis generation.4. gastroduodenal malfunction: (1) gastric emptying is abnormal.(2) gastroduodenal reflux is when sphincter of pylorus tension force and LES pressure are simultaneously low, hydrochloric acid in gastric juice and pepsin, cholic acid in duodenal juice, pancreatic juice and hemolytic lecithin etc. all reflux can enter esophagus simultaneously, corrode the cuticular layer of esophageal epithelial cell, and make it thinning or come off.H+ in reflux thing and pepsin then go deep into esophageal tissue through the squamous epithelial of new life, cause esophagitis.5. ceasma hernia: commonly sliding hernia.Esophagus and stomach junction surface enters thoracic cavity with body of stomach upward displacement.The rising of body of stomach makes diaphragm foot separately, and ceasma expands.Hernical sac hour, with position, exerts oneself and coughs and slide up and down.Hernical sac no longer slides after increasing, and changes the normal anatomical relationship near ceasma, causes esophagus and stomach junction surface dysraphism.The His angle that the hernia of stomach enters to make esophagus to enter stomach disappears, and diaphragm esophagus film is elongated, thinning, and abdomen section esophagus moves, and the closure function at junction surface is worsened further.Generation reflux esophagitis more than half in the patient of ceasma hernia.6. vomiting during pregnancy: the ceasma hernia occurred because gestation adds intraabdominal pressure can cause reflux esophagitis, but divide a puerperium to recover, need not anyly treat.Vomiting and long-term singultus also can make cardia often open and reflux esophagitis occurs, and can recover normal after removing the cause of disease.7. other diseases: neonate and infant, in growth course, because there being inferior esophageal sphincter dysfunction, reflux occur, with early children development, major part can alleviate.Under primary esophageal, sphincter function is bad makes incompetence, and because organic disease is as distal esophagus and pars cardiaca tumor, scleroderma with variously cause pyloric obstruction etc., all can cause reflux esophagitis.
Therefore, normally the bile of reflux and gastric acid combined effect, in the result of Esophageal Mucosa, and before bile causes esophageal injury, must pre-exist pylorus and LES functional disorder to reflux esophagitis; Reflux esophagitis person is many with gastritis.Sliding hiatal hernia because of often cause LES and pylorus peristaltic function imbalance and easy concurrent primary disease; Duodenal ulcer accompanies by high gastric acid secretion more and easily causes antral spasm and pylorus peristaltic function obstacle, therefore concurrent primary disease is also more.Fat, a large amount of seroperitoneum, latter half of gestation, gastric retention table increase and the factor such as tobacco and wine medicine all can bring out this disease.
Authorization Notice No. is CN 102579389 B(application number 201210072887.6) Chinese patent literature disclose a kind of by name " a kind of pharmaceutical composition ", this pharmaceutical composition comprises lansoprazole and enteric composition, and enteric composition is two kinds in polyacrylic resin I, polyacrylic resin II and polyacrylic resin III; Wherein polyacrylic resin I and polyacrylic resin II weight ratio are 1:10-15; Wherein polyacrylic resin II and polyacrylic resin III weight ratio are 1:11-17; Wherein polyacrylic resin I and polyacrylic resin III weight ratio are 1:5-10; Wherein pharmaceutical composition comprises lansoprazole 15 weight portion, filler 20-50 weight portion, disintegrating agent 10-30 weight portion, alkaline stabiliser 10-30 weight portion, solubilizing agent 5-10 weight portion, lubricant 0.5-1 weight portion.Publication number is CN 1915350A(application number 200510090389) Chinese patent literature disclose a kind of by name " a kind of drug regimen for the treatment of gastropathy ", the Pharmaceutical formulations such as it mainly contains Chinese herbal medicine Rhizoma Atractylodis, the Siberian cocklebur Pericarpium Citri Reticulatae that rues, eastern short, bristly hair or beard, Massa Medicata Fermentata, Fructus Hordei Germinatus, Concha Ostreae, river fore-telling, Fructus Amomi, Aloe, the Rhizoma Atractylodis Macrocephalae, Semen Lablab Album, Cera Flava form.
In a word, Chinese medicine achieves certain effect in treatment gastroduodenal and reflux esophagitis, but also exist fundamentally can not cure, take effect slowly, the deficiency such as toxic and side effects again, need to be improved further, most importantly, current existence be all pure Chinese medicinal preparation, long-term taking is in evil case.
Summary of the invention
For the present situation that prior art is slightly not enough, an object of the present invention is to provide a kind of health-caring capsule for the treatment of the reflux esophagitis that gastroduodenal malfunction causes, health-caring capsule scientific formula of the present invention, instant effect, fundamentally can cure the reflux esophagitis that gastroduodenal malfunction causes, and preparation method is simple, taking convenience, be easy to carry.
Another object of the present invention is to the preparation method of the health-caring capsule of the reflux esophagitis providing above-mentioned treatment gastroduodenal malfunction to cause.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, each crude drug is as follows, is weight portion: Fructus Aurantii Immaturus 5-15, Rhizoma Polygoni Paleachi 6-12, Semen Maydis 12-25, Fructus Cucurbitae moschatae 8-16, Concha Arcae 6-12, Radix Raphani 5-15, Os Draconis 3-7, Fructus Hippophae 7-15, Semen Sesami Nigrum 10-20, Semen Juglandis 3-9, Herba Artemisiae Anomalae 9-15, Rhizoma Atractylodis Macrocephalae 5-15, Myrrha 3-12, Fructus psidii guajavae immaturus 3-8, Caulis Bambusae In Taenia 10-20.
The health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, preferred scheme, each crude drug is as follows, be weight portion: Fructus Aurantii Immaturus 8-13, Rhizoma Polygoni Paleachi 8-10, Semen Maydis 16-21, Fructus Cucurbitae moschatae 12-14, Concha Arcae 8-10, Radix Raphani 8-13, Os Draconis 4-6, Fructus Hippophae 10-12, Semen Sesami Nigrum 13-18, Semen Juglandis 5-7, Herba Artemisiae Anomalae 11-13, Rhizoma Atractylodis Macrocephalae 8-13, Myrrha 5-10, Fructus psidii guajavae immaturus 4-6, Caulis Bambusae In Taenia 13-18.
The health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, better preferred scheme, each crude drug is as follows, be weight portion: Fructus Aurantii Immaturus 10, Rhizoma Polygoni Paleachi 9, Semen Maydis 18, Fructus Cucurbitae moschatae 13, Concha Arcae 9, Radix Raphani 10, Os Draconis 5, Fructus Hippophae 11, Semen Sesami Nigrum 15, Semen Juglandis 6, Herba Artemisiae Anomalae 12, the Rhizoma Atractylodis Macrocephalae 11, Myrrha 8, Fructus psidii guajavae immaturus 5, Caulis Bambusae In Taenia 15.
The preparation method of the health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, step is as follows:
1. Os Draconis and Concha Arcae are placed in the hot water of 80-100 DEG C, when water temperature is cooled to room temperature, add Sal, after Sal melts completely, soak 10-30 minute (preferably 20 minutes), taking-up is dried, and is ground into smalls stand-by with pulverizer;
2. get the Rhizoma Atractylodis Macrocephalae and Myrrha to clean, drain away the water, high temperature sterilization 1-5 minute, section, uses rice vinegar uniform spraying, mix after slightly vexed 10 minutes with Semen Sesami Nigrum and Semen Juglandis, puts in the hot pot that dryouies and fries 3-8 minute with low baking temperature, take out, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Fructus Aurantii Immaturus, Rhizoma Polygoni Paleachi, Fructus Hippophae, Herba Artemisiae Anomalae and Caulis Bambusae In Taenia, little fire dries 10-30 minute slowly, dries in the air coolly to grind to form smalls, crosses 80-120 mesh sieve (preferably 100 mesh sieves);
4. Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus are cleaned, be cut into coin-size stand-by;
5. Semen Maydis is eluriated 1-3 time, add Semen Maydis weight 8-12 water doubly, soak after 1 hour, big fire adds step 4. gains after boiling, after big fire boils 4-8 minute, be blended into cold water, turn slow fire boiling 20-40 minute, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus, add step 1.-3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste at 50-70 DEG C of dry 10-18 hour, make granule, the granule be prepared into is packed according to the preparation technology of capsule and be get final product.
The preparation method of above-mentioned health-caring capsule, 1. Os Draconis and Concha Arcae are placed in the hot water (preferably Os Draconis and Concha Arcae being placed in the hot water of 90 DEG C) of 85-95 DEG C by step.
The preparation method of above-mentioned health-caring capsule, step 2. high temperature sterilization 2-4 minute (preferred high temperature sterilization 3 minutes).
The preparation method of above-mentioned health-caring capsule, step 3. little fire is dried 15-25 minute (preferred little fire dries 20 minutes slowly) slowly.
The preparation method of above-mentioned health-caring capsule, 5. step adds Semen Maydis weight 9-11 water (preferably adding the water of Semen Maydis weight 10 times) doubly.
The preparation method of above-mentioned health-caring capsule, step after 5. big fire boils 5-7 minute, is blended into cold water, turns slow fire boiling 25-35 minute (preferred big fire boil 6 minutes after, be blended into cold water, turn slow fire boiling 30 minutes).
The preparation method of above-mentioned health-caring capsule, step 6. thick paste, at 55-65 DEG C of dry 12-16 hour, makes granule (preferred thick paste, 60 DEG C of dryings 14 hours, makes granule).
The present invention is to the Be very effective of anti-fatigue anti-senility, and be the therapeutic effect making the present invention reach best, every day 3 times, taking respectively at half an hour after breakfast, lunch and dinner, each 2, warm water delivery service, 10 days is a course for the treatment of.
The pharmacological effect of each raw material is respectively:
Fructus Aurantii Immaturus: Fructus Aurantii Immaturus, YIN nourishing of enriching blood, moisturizes, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.Blood YIN nourishing, moisturizes, hemostasis.For blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
Rhizoma Polygoni Paleachi: base is former: be the rhizome of Polygonaceae arsesmart Rhizoma Polygoni Paleachi.Composition: Rhizoma Polygoni Paleachi rhizome is containing Combination tannin.The property of medicine: bitter, acrid, cold.Function cures mainly: dissipating blood stasis stops blooding, therapeutic method to keep the adverse QI flowing downwards removing food stagnancy, removing toxic substances, dampness removing.Zhu Zhi WEIJIA is gathered, traumatic injury, traumatic hemorrhage, spits blood, spitting of blood, epistaxis, amenorrhea, metrorrhagia, chronic gastritis, taste-blindness rate, and food stagnation is stagnated, dysentery, enteritis, edema, sore, venom, burn and scald.
Semen Maydis: Semen Maydis is the health-care good product in coarse grain, rather favourable to the health of human body: the compositions such as the vitamin B6 in Semen Maydis, nicotinic acid, there is stimulating gastrointestinal and wriggle, accelerate the characteristic of defecate, can prevent treating constipation, gastropathy, enteritis, intestinal cancer etc.Semen Maydis is rich in vitamin C, dextrinosan etc., has longevity, beautification function.Nutrient substance contained by corn germ point has enhancing human metabolism, adjustment nervous function.Can play and make skin delicacy smooth, suppress, delay wrinkle generation effect.Semen Maydis to have in tune effect of appetizing and blood fat reducing, reduction serum cholesterol.It is relevant with their main edible corn that hypertension is not easily suffered from by Central America American Indian.
Fructus Cucurbitae moschatae: Fructus Cucurbitae moschatae not only has higher edibility, and have very important dietary function.Carry according to " the southern regions of the Yunnan Province book on Chinese herbal medicine ": Fructus Cucurbitae moschatae is warm in nature, and sweet in the mouth is nontoxic, enters spleen, stomach two warp, energy moistening lung qi-benefitting, evacuation of pus of reducing phlegm, anthelmintic is detoxified, and controls and coughs Zhichuan, treats lung abscess constipation, and has the effect such as diuresis, beauty treatment.The bile of Fructus Cucurbitae moschatae secretion can promote enterogastric peristalsis, helps food digestion, and simultaneously pectin wherein can allow people from the stimulation of coarse food, protects our Wei Jiao road mucosa.Fructus Cucurbitae moschatae can make the ability that Liver and kidney function is restored and regenerates in addition, because Fructus Cucurbitae moschatae can eliminate the mutation effect of carcinogen nitrous acid.Also have the composition of a kind of " cobalt " in Fructus Cucurbitae moschatae, after edible, have blood tonification effect.Fructus Cucurbitae moschatae contains abundant vitamin A, b, c and mineral, 8 required seed amino acids and the required histidine of child, the trace element such as soluble fiber, phylloxanthin and phosphorus, potassium, calcium, magnesium, zinc, silicon.Modern age threpsology and medical science show, polyphagia Fructus Cucurbitae moschatae effectively can prevent and treat hypertension, diabetes and hepatic lesions, improve human body immunity.
Concha Arcae: have another name called Carnis Arca inflata shell, watt room, blood clam skin, row of tiles on a roof clam skin, for Carnis Arca inflata section Carnis Arca inflata belongs to the shell that animal Scapharca subcrenata, Scapharca broughtonii and Tegillarca granosa belong to animal Tegillarca granosa.The property of medicine: matter is hard, sweet in the mouth, salty, property is put down.Composition: main component is calcium carbonate, also containing a small amount of calcium phosphate and magnesium, ferrum, silicate.Find according to modern pharmacological research, this medical instrument has effect of expectorant blood stasis dispelling, hard masses softening and resolving, relieving gastric hyperacidity to alleviate stomachache, for pertinacious phlegm chronic cough, and stomachache acid regurgitation, traumatic hemorrhage, gastric and duodenal ulcers.
Radix Raphani: base is former: be fresh of Cruciferae Radix Raphani platymiscium Radix Raphani.Composition: root contains glycoside glucosinolate, glucose raphanin, raphanusin.Phenolic acids: P-coumaric acid, caffeic acid, ferulic acid, phenylpyruvic acid, gentisic acid etc.The property of medicine: acrid, sweet, cool; Ripe person is sweet, flat.Return spleen, stomach, lung, large intestine channel.Function cures mainly: help digestion, and the therapeutic method to keep the adverse QI flowing downwards is reduced phlegm, hemostasis.Cure mainly dyspepsia, food stagnation distension, acid regurgitation, regurgitation of food from the stomach, tells food, and hemorrhoidal hamorrhage is had loose bowels, dysentery, constipation, phlegm-heat cough, discomfort in the throat, hemoptysis, and spit blood, epistaxis, has blood in stool, and quenches one's thirst, and drenches worm.Outer treatment skin ulcer abscess, damage congestive edema, scalds and chilblain.
Os Draconis: base is former: for mammal in ancient times resembles the Skeletal Fossils of class, rhinoceros class, Hippocampal cortex, bovine, deer class etc.Composition: Os Draconis, mainly containing calcium carbonate and calcium phosphate, still contain ferrum, potassium, sodium, chlorine, sulfate radical etc.The property of medicine: puckery, sweet, flat.GUIXIN, liver, kidney, large intestine channel.Function cures mainly: tranquilizing mind, suppressing the hyperactive liver and subsiding YANG, restrains astringent or styptic treatment for spontaneous sweating.Cure mainly cardiopalmus, seized with terror swollen, insomnia, forgetful, infantile convulsion, demented, dizzy, spontaneous sweating, the seminal emission enuresis, bleeding not during menses, chronic diarrhea and dysentery, ulcer does not close up and eczema for a long time.
Fructus Hippophae: base is former: be the fruit of Elaeangnaceae hippophae plant Chinese sea buckthorn and yunnan seabuckthorn.Composition: sea buckthorn fruit is containing pyrite constituents: isorhamnetin, isorhamnetin-3-O--D-Glucose glycosides, rutin, astragalin and Quercetin and kaempferol are the low glucosides etc. of aglycon.The property of medicine: " Chinese herbal medicine is commonly used in Tibet ": " warm in nature, sour in the mouth, puckery." function cures mainly: relieving cough and resolving phlegm, invigorating the stomach and promoting digestion, promoting blood circulation to remove blood stasis.Cure mainly cough with copious phlegm, pulmonary abscess, dyspepsia, abdominal pain due to retention of food, stomachache, enteritis, amenorrhea, traumatic injury congestive edema.
Semen Sesami Nigrum: Semen Sesami Nigrum medicine-food two-purpose, has health-care effecies such as " invigorating the liver and kidney, grow the five internal organs, benefiting essence-blood, intestine moistening is dry ", is regarded as nourishing holy product.Being because containing high quality protein and abundant mineral on the one hand, is because the sesamin containing abundant unsaturated fatty acid, vitamin E and preciousness and melanin on the other hand.
Semen Juglandis: Semen Juglandis is the sarcocarp in walnut kernel, has another name called semen juglandis, Semen Juglandis.1, the strong body of tonify deficiency, provides nutrition: prove through zoopery, containing the mixing-in fat diet of Oleum Juglandis, body weight can be made to increase, and serum albumin increases, and blood cholesterol levels raises comparatively slow, therefore Semen Juglandis is the tonic product of rare a kind of higher fatty acid property material.2, anti-inflammation and sterilization, maintaining skin: Semen Persicae has direct inhibiting bacteria and diminishing inflammation effect.According to clinical report, Semen Juglandis is mashed the Semen Juglandis tar zinc oxide paste made, treatment dermatitis, eczema, effective percentage can reach 100%.The oils and fats that Semen Juglandis is rich in, is conducive to moist skin, keeps human activity.3, cancer-resisting: experiment proves, Semen Juglandis effective ingredient has inhibitory action to mice S37 tumor.Semen Juglandis skill to kinds of tumors, as esophageal carcinoma, gastric cancer, nasopharyngeal carcinoma, pulmonary carcinoma, thyroid carcinoma, lymphosarcoma etc. have certain inhibitory action.In addition, Semen Juglandis also has analgesia to cancer patient, promotes the effect such as leukocyte and the liver protecting.4, brain-strengthening is anti-old: Semen Juglandis contains more protein and the required unsaturated fatty acid of human nutrition, and these compositions are all the important substance of cerebral tissue cellular metabolism, can nursing brain cells, cerebral function improvement.5, purify the blood, reduce cholesterol: Semen Juglandis can reduce the absorption of intestinal to cholesterol.And solubilized cholesterol, " the dirt impurity " got rid of in blood vessel wall makes blood purification, thus provides better fresh blood for human body.So Semen Juglandis prevents arteriosclerosis, reduce the effect of cholesterol.In addition, Semen Juglandis also can be used for treating non-insulin-dependent diabetes mellitus.
Herba Artemisiae Anomalae: have another name called Herba Artemisiae Anomalae grass, Herba Senecionis Scandentis is the wounded in the battle herb of Compositae sagebruss artemisia anomalas.The property of medicine: stem is cylindrical, surperficial brown color or brown-green, matter is hard and crisp, frangibility, the integrated spike panicle of head inflorescence, withered yellow, gas fragrance, bitter in the mouth, pungent, warm in nature.Composition: mainly containing arteanoflavone, tricin, apigenin, Palmic acid etc.Find according to modern pharmacological research, this medical instrument has effect of anti-hypoxia, blood circulation promoting and blood stasis dispelling, removing food stagnancy, hemostasia and detumescence, for amenorrhea due to stagnation of blood, and abdominal pain due to retention of food, hematuria, the diseases such as scald.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth, sweet, warm in nature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Myrrha: Myrrha (Commiphora myrrha Eng1.), has another name called myrrh, other also have the another names such as the raw bright Myrrha of bright Myrrha Myrrha myrrh Myrrha (processed) Myrrha (processed) Myrrha (parched with vinegar) Myrrha.For olive subject plant Herba Violae tree or the dry resin of Ha Didingshu.Main product is in African Somalia, Ethiopia and India and other places.Gather the white oleo-gum-resin of being oozed out by bark crack, in air, become rufous and hard nahlock.After smashing, fry to coke black and apply.Cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There is the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation.Be in the Orient a kind ofly to invigorate blood circulation, blood stasis dispelling, pain relieving, stomach invigorating Chinese medicine.
Fructus psidii guajavae immaturus: be rich in grey matter, ferrum, calcium, phosphorus and various vitamin, has the effects such as treatment diabetes, pre-anti-diarrhea.A large amount of blood sugar lowering prescription being main component with the leaf of Fructus psidii guajavae immaturus and fruit is had in traditional Chinese medical science prescription.Fructus psidii guajavae immaturus is one of autochthonal fruit at last in Taiwan, and belonging to the diet fruit of first-class in Taiwan, is the good diet fruit that market can be seen, also can prophylaxis of hypertension, and obesity, can also toxin expelling facilitating digestion.Can enhance metabolism, regulate physiological function, often guarantor healthy, very suitable patients with diabetes mellitus, and the vitamin C in Fructus psidii guajavae immaturus there is the effect controlling male infertility.Spleen invigorating removing food stagnancy; Relieving diarrhea with astringents.Staple food amasss glutted; Infantile malnutrition; Diarrhoea; Dysentery; Proctoptosis; Metrorrhagia.Astringent therapy antidiarrheal; Pain relieving sore.Main dysentery; Epigastric pain; Toothache; Diabetes; Skin infection; Venom.
Caulis Bambusae In Taenia: Caulis Bambusae In Taenia is traditional Chinese medical science medical material is the dry intermediate layer of stem stalk of grass bambusa breviflora Munro, major part allusion quotation bamboo or phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle.The whole year all can gather and process, and gets fresh stem, and removing crust, spreads to strand by slightly viridant intermediate layer, or chip, tie up bunchy, dry in the shade.The former claims " loose Caulis Bambusae In Taenia ", and the latter claims " neat Caulis Bambusae In Taenia ".Nature and flavor cold nature, sweet in the mouth.Function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting.Expectorant, dysphoria with smothery sensation vomiting, palpitation with fear insomnia, middle wind-phlegm fan, aphasia with stiff tongue, gastropyretic vomiting, pregnancy reactions, frequent fetal movement is held under the arm for phlegm-heat cough, gallbladder fire.
The beneficial effect of health-caring capsule of the present invention is, low raw-material cost, any toxic and side effects can not be brought to patient, and it is evident in efficacy, fundamentally can cure the reflux esophagitis that gastroduodenal malfunction causes, the health-caring capsule that the present invention treats the reflux esophagitis that gastroduodenal malfunction causes selects Fructus Aurantii Immaturus, Rhizoma Polygoni Paleachi, Semen Maydis, Fructus Cucurbitae moschatae, Concha Arcae, Radix Raphanis etc. have nourishing the stomach, control abdominal pain, contribute to digestion medicine and carry out compatibility, medicine is made to produce synergism, fundamentally can treat the reflux esophagitis that gastroduodenal malfunction causes.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, each crude drug is as follows, is weight portion (getting 10g for every part): Fructus Aurantii Immaturus 5, Rhizoma Polygoni Paleachi 6, Semen Maydis 12, Fructus Cucurbitae moschatae 8, Concha Arcae 6, Radix Raphani 5, Os Draconis 3, Fructus Hippophae 7, Semen Sesami Nigrum 10, Semen Juglandis 3, Herba Artemisiae Anomalae 9, the Rhizoma Atractylodis Macrocephalae 5, Myrrha 3, Fructus psidii guajavae immaturus 3, Caulis Bambusae In Taenia 10.
The preparation method of above-mentioned health-caring capsule, step is as follows:
1. Os Draconis and Concha Arcae are placed in the hot water of 80 DEG C, when water temperature is cooled to room temperature, add Sal, after Sal melts completely, soak 10 minutes, taking-up is dried, and is ground into smalls stand-by with pulverizer;
2. get the Rhizoma Atractylodis Macrocephalae and Myrrha to clean, drain away the water, high temperature sterilization 1 minute, section, uses rice vinegar uniform spraying, mix after slightly vexed 10 minutes with Semen Sesami Nigrum and Semen Juglandis, put interior the low baking temperature of hot pot dryouied and fry 3 minutes, taking-up, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Fructus Aurantii Immaturus, Rhizoma Polygoni Paleachi, Fructus Hippophae, Herba Artemisiae Anomalae and Caulis Bambusae In Taenia, little fire dries 10 minutes slowly, dries in the air coolly to grind to form smalls, crosses 80 mesh sieves;
4. Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus are cleaned, be cut into coin-size stand-by;
5. Semen Maydis is eluriated 1 time, add the water of Semen Maydis weight 8 times, soak after 1 hour, big fire adds step 4. gains after boiling, after big fire boils 4 minutes, be blended into cold water, turn slow fire boiling 20 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus, add step 1.-3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 50 DEG C of dryings 10 hours, make granule, the granule be prepared into is packed according to the preparation technology of capsule and be get final product.
embodiment 2the health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, each crude drug is as follows, is weight portion (getting 20g for every part): Fructus Aurantii Immaturus 15, Rhizoma Polygoni Paleachi 12, Semen Maydis 25, Fructus Cucurbitae moschatae 16, Concha Arcae 12, Radix Raphani 15, Os Draconis 7, Fructus Hippophae 15, Semen Sesami Nigrum 20, Semen Juglandis 9, Herba Artemisiae Anomalae 15, the Rhizoma Atractylodis Macrocephalae 15, Myrrha 12, Fructus psidii guajavae immaturus 8, Caulis Bambusae In Taenia 20.
The preparation method of above-mentioned health-caring capsule, step is as follows:
1. Os Draconis and Concha Arcae are placed in the hot water of 100 DEG C, when water temperature is cooled to room temperature, add Sal, after Sal melts completely, soak 30 minutes, taking-up is dried, and is ground into smalls stand-by with pulverizer;
2. get the Rhizoma Atractylodis Macrocephalae and Myrrha to clean, drain away the water, high temperature sterilization 5 minutes, section, uses rice vinegar uniform spraying, mix after slightly vexed 10 minutes with Semen Sesami Nigrum and Semen Juglandis, put interior the low baking temperature of hot pot dryouied and fry 8 minutes, taking-up, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Fructus Aurantii Immaturus, Rhizoma Polygoni Paleachi, Fructus Hippophae, Herba Artemisiae Anomalae and Caulis Bambusae In Taenia, little fire dries 30 minutes slowly, dries in the air coolly to grind to form smalls, crosses 120 mesh sieves;
4. Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus are cleaned, be cut into coin-size stand-by;
5. Semen Maydis is eluriated 3 times, add the water of Semen Maydis weight 12 times, soak after 1 hour, big fire adds step 4. gains after boiling, after big fire boils 8 minutes, be blended into cold water, turn slow fire boiling 40 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus, add step 1.-3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 70 DEG C of dryings 18 hours, make granule, the granule be prepared into is packed according to the preparation technology of capsule and be get final product.
model case one:liu XX, female, 42 years old, Lanxi County, Harbin personage, peasant.Epigastrium distending pain was there is without obvious inducement in patient before March, especially, in 1 hour after the meal, cross and can alleviate gradually, do not draw attention, any Drug therapy is not taken yet, As time goes on, Upper abdominal pain increases the weight of, and occurs burning sample pain, with feeling sick, the discomfort such as acid regurgitation, belch, so remove examination in hospital, be diagnosed as the reflux esophagitis that gastroduodenal malfunction causes on inspection, doctor advised takes embodiment 2 gained health-caring capsule.
Take the present embodiment 2 gained health-caring capsule, take 5 days, patient's malaise symptoms alleviates, acid regurgitation, feel sick etc. disease disappear; Take 10 days, patient's malaise symptoms is clearly better, and partial symptoms disappears; Continue to take 10 days, patient's self-induction is fully recovered, and any discomfort symptom does not appear in period in a medicine.
embodiment 3the health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, each crude drug is as follows, is weight portion (getting 30g for every part): Fructus Aurantii Immaturus 8, Rhizoma Polygoni Paleachi 8, Semen Maydis 16, Fructus Cucurbitae moschatae 12, Concha Arcae 8, Radix Raphani 8, Os Draconis 4, Fructus Hippophae 10, Semen Sesami Nigrum 13, Semen Juglandis 5, Herba Artemisiae Anomalae 11, the Rhizoma Atractylodis Macrocephalae 8, Myrrha 5, Fructus psidii guajavae immaturus 4, Caulis Bambusae In Taenia 13.
The preparation method of above-mentioned health-caring capsule, step is as follows:
1. Os Draconis and Concha Arcae are placed in the hot water of 85 DEG C, when water temperature is cooled to room temperature, add Sal, after Sal melts completely, soak 15 minutes, taking-up is dried, and is ground into smalls stand-by with pulverizer;
2. get the Rhizoma Atractylodis Macrocephalae and Myrrha to clean, drain away the water, high temperature sterilization 2 minutes, section, uses rice vinegar uniform spraying, mix after slightly vexed 10 minutes with Semen Sesami Nigrum and Semen Juglandis, put interior the low baking temperature of hot pot dryouied and fry 5 minutes, taking-up, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Fructus Aurantii Immaturus, Rhizoma Polygoni Paleachi, Fructus Hippophae, Herba Artemisiae Anomalae and Caulis Bambusae In Taenia, little fire dries 10-30 minute slowly, dries in the air coolly to grind to form smalls, crosses 90 mesh sieves;
4. Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus are cleaned, be cut into coin-size stand-by;
5. Semen Maydis is eluriated 1 time, add the water of Semen Maydis weight 9 times, soak after 1 hour, big fire adds step 4. gains after boiling, after big fire boils 5 minutes, be blended into cold water, turn slow fire boiling 25 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus, add step 1.-3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 55 DEG C of dryings 12 hours, make granule, the granule be prepared into is packed according to the preparation technology of capsule and be get final product.
model case two:cattle XX, man, 40 years old, people from Jiyang County, Jinan City, the leader of certain unit.Dinner party is often gone out in patient's readme at ordinary times, drink a lot, finish off at every turn and all can occur regurgitation, the diseases such as belch, because stomach is not fine always, so diet is also paid much attention to, occur that epigastrium causalgia continues one week recently, regurgitation, the diseases such as belch are also more frequent, take motilium, effect is undesirable, remove examination in hospital, find that patient has chest and diaphragm pain, the discomforts such as flatulence gastric acid, be diagnosed as the reflux esophagitis that gastroduodenal malfunction causes, many medicines have been opened in hospital, go home to take medicine a period of time, symptom is without significant change, be not intended on TV find health-caring capsule of the present invention.
Take the present embodiment 3 gained health-caring capsule, take 7 days, patient's Upper abdominal pain alleviates, and regurgitation, belch number of times obviously reduce; Take 1 day, patient's malaise symptoms disappears substantially, and be clearly better comparatively, continue to take 5 days, patient's malaise symptoms disappears completely, and self-induction is fully recovered, and continues to take and is consolidated for 10 days.
embodiment 4the health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, each crude drug is as follows, is weight portion (getting 40g for every part): Fructus Aurantii Immaturus 13, Rhizoma Polygoni Paleachi 10, Semen Maydis 21, Fructus Cucurbitae moschatae 14, Concha Arcae 10, Radix Raphani 13, Os Draconis 6, Fructus Hippophae 12, Semen Sesami Nigrum 18, Semen Juglandis 7, Herba Artemisiae Anomalae 13, the Rhizoma Atractylodis Macrocephalae 13, Myrrha 10, Fructus psidii guajavae immaturus 6, Caulis Bambusae In Taenia 18.
The preparation method of above-mentioned health-caring capsule, step is as follows:
1. Os Draconis and Concha Arcae are placed in the hot water of 95 DEG C, when water temperature is cooled to room temperature, add Sal, after Sal melts completely, soak 25 minutes, taking-up is dried, and is ground into smalls stand-by with pulverizer;
2. get the Rhizoma Atractylodis Macrocephalae and Myrrha to clean, drain away the water, high temperature sterilization 4 minutes, section, uses rice vinegar uniform spraying, mix after slightly vexed 10 minutes with Semen Sesami Nigrum and Semen Juglandis, put interior the low baking temperature of hot pot dryouied and fry 7 minutes, taking-up, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Fructus Aurantii Immaturus, Rhizoma Polygoni Paleachi, Fructus Hippophae, Herba Artemisiae Anomalae and Caulis Bambusae In Taenia, little fire dries 25 minutes slowly, dries in the air coolly to grind to form smalls, crosses 110 mesh sieves;
4. Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus are cleaned, be cut into coin-size stand-by;
5. Semen Maydis is eluriated 3 times, add the water of Semen Maydis weight 11 times, soak after 1 hour, big fire adds step 4. gains after boiling, after big fire boils 7 minutes, be blended into cold water, turn slow fire boiling 35 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus, add step 1.-3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 65 DEG C of dryings 16 hours, make granule, the granule be prepared into is packed according to the preparation technology of capsule and be get final product.
embodiment 5the health-caring capsule of the reflux esophagitis that treatment gastroduodenal malfunction causes, each crude drug is as follows, is weight portion (getting 50g for every part): Fructus Aurantii Immaturus 10, Rhizoma Polygoni Paleachi 9, Semen Maydis 18, Fructus Cucurbitae moschatae 13, Concha Arcae 9, Radix Raphani 10, Os Draconis 5, Fructus Hippophae 11, Semen Sesami Nigrum 15, Semen Juglandis 6, Herba Artemisiae Anomalae 12, the Rhizoma Atractylodis Macrocephalae 11, Myrrha 8, Fructus psidii guajavae immaturus 5, Caulis Bambusae In Taenia 15.
The preparation method of above-mentioned health-caring capsule, step is as follows:
1. Os Draconis and Concha Arcae are placed in the hot water of 90 DEG C, when water temperature is cooled to room temperature, add Sal, after Sal melts completely, soak 20 minutes, taking-up is dried, and is ground into smalls stand-by with pulverizer;
2. get the Rhizoma Atractylodis Macrocephalae and Myrrha to clean, drain away the water, high temperature sterilization 3 minutes, section, uses rice vinegar uniform spraying, mix after slightly vexed 10 minutes with Semen Sesami Nigrum and Semen Juglandis, put interior the low baking temperature of hot pot dryouied and fry 6 minutes, taking-up, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Fructus Aurantii Immaturus, Rhizoma Polygoni Paleachi, Fructus Hippophae, Herba Artemisiae Anomalae and Caulis Bambusae In Taenia, little fire dries 20 minutes slowly, dries in the air coolly to grind to form smalls, crosses 100 mesh sieves;
4. Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus are cleaned, be cut into coin-size stand-by;
5. Semen Maydis is eluriated 2 times, add the water of Semen Maydis weight 10 times, soak after 1 hour, big fire adds step 4. gains after boiling, after big fire boils 6 minutes, be blended into cold water, turn slow fire boiling 30 minutes, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus, add step 1.-3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste 60 DEG C of dryings 14 hours, make granule, the granule be prepared into is packed according to the preparation technology of capsule and be get final product.
experimental exampleembodiment 5 gained health-caring capsule clinical practice: in order to verify the definite curative effect of health-caring capsule of the present invention to the reflux esophagitis that gastroduodenal malfunction causes, clinical selected part patient, as observation contrast object, specifically chooses reference method as follows:
1. little course of disease group: choose that the course of disease is 10-20 days, reflux esophagitis 2 people A and B that pathology and agematched gastroduodenal malfunction cause contrast for a pair, it is 100 right to contrast altogether, and record is on average fully recovered natural law, efficiently individual quantity, invalid number;
2. course of disease group in: choosing the course of disease is that reflux esophagitis 2 people A and B that individual month of 1-2, pathology and agematched gastroduodenal malfunction cause contrasts for a pair, and contrast 100 is right altogether, records natural law of on average fully recovering, efficiently individual quantity, invalid number;
3. severe disease journey group: choosing the course of disease is that reflux esophagitis 2 people A and B that individual month of 3-5, pathology and agematched gastroduodenal malfunction cause contrasts for a pair, and contrast 100 is right altogether, records natural law of on average fully recovering, efficiently individual quantity, invalid number;
In all course of disease groups, the reflux esophagitis medicine (conventional medicine such as motilium, SIDASHU) that A all uses conventional therapy gastroduodenal malfunction to cause, B all uses the embodiment of the present invention 5 gained health-caring capsule.
Criterion, recovery from illness: clinical symptoms disappears completely, and the malaise symptoms such as Upper abdominal pain, beloved wife disappears completely; Effective: clinical symptoms is obviously improved, part malaise symptoms disappears; Invalid: clinical symptoms is unchanged or increase the weight of.Result is as following table 1:
Table 1: embodiment 5 gained health-caring capsule compliance test result
Total efficiently individual quantity=efficiently individual quantity+recovery from illness number
As shown in Table 1, the average curative day of little course of disease group is 7 days, and effective percentage reaches 99%; The average curative day of middle course of disease group is 15 days, and cure rate is 98%; The average curative day of severe disease journey group is 20 days, and effective percentage can reach 97%, and successful is better than A group.Take health-caring capsule therapeutic effect of the present invention significantly and instant effect, effective percentage ensures more than 97%.And recovery from illness patient tracing observation is found, recur after not having a routine drug withdrawal, therefore can prove health-caring capsule of the present invention be a kind of effectively and the Chinese medicine of reflux esophagitis that causes of the treatment gastroduodenal malfunction of safety.

Claims (10)

1. treat the health-caring capsule of the reflux esophagitis that gastroduodenal malfunction causes, it is characterized in that: each crude drug is as follows, is weight portion: Fructus Aurantii Immaturus 5-15, Rhizoma Polygoni Paleachi 6-12, Semen Maydis 12-25, Fructus Cucurbitae moschatae 8-16, Concha Arcae 6-12, Radix Raphani 5-15, Os Draconis 3-7, Fructus Hippophae 7-15, Semen Sesami Nigrum 10-20, Semen Juglandis 3-9, Herba Artemisiae Anomalae 9-15, Rhizoma Atractylodis Macrocephalae 5-15, Myrrha 3-12, Fructus psidii guajavae immaturus 3-8, Caulis Bambusae In Taenia 10-20.
2. the health-caring capsule of reflux esophagitis that causes for the treatment of gastroduodenal malfunction according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Fructus Aurantii Immaturus 8-13, Rhizoma Polygoni Paleachi 8-10, Semen Maydis 16-21, Fructus Cucurbitae moschatae 12-14, Concha Arcae 8-10, Radix Raphani 8-13, Os Draconis 4-6, Fructus Hippophae 10-12, Semen Sesami Nigrum 13-18, Semen Juglandis 5-7, Herba Artemisiae Anomalae 11-13, Rhizoma Atractylodis Macrocephalae 8-13, Myrrha 5-10, Fructus psidii guajavae immaturus 4-6, Caulis Bambusae In Taenia 13-18.
3. the health-caring capsule of reflux esophagitis that causes for the treatment of gastroduodenal malfunction according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Fructus Aurantii Immaturus 10, Rhizoma Polygoni Paleachi 9, Semen Maydis 18, Fructus Cucurbitae moschatae 13, Concha Arcae 9, Radix Raphani 10, Os Draconis 5, Fructus Hippophae 11, Semen Sesami Nigrum 15, Semen Juglandis 6, Herba Artemisiae Anomalae 12, the Rhizoma Atractylodis Macrocephalae 11, Myrrha 8, Fructus psidii guajavae immaturus 5, Caulis Bambusae In Taenia 15.
4. the preparation method of the health-caring capsule of the reflux esophagitis that the treatment gastroduodenal malfunction according to any one of claim 1-3 causes, is characterized in that: step is as follows:
1. Os Draconis and Concha Arcae are placed in the hot water of 80-100 DEG C, when water temperature is cooled to room temperature, add Sal, after Sal melts completely, soak 10-30 minute (preferably 20 minutes), taking-up is dried, and is ground into smalls stand-by with pulverizer;
2. get the Rhizoma Atractylodis Macrocephalae and Myrrha to clean, drain away the water, high temperature sterilization 1-5 minute, section, uses rice vinegar uniform spraying, mix after slightly vexed 10 minutes with Semen Sesami Nigrum and Semen Juglandis, puts in the hot pot that dryouies and fries 3-8 minute with low baking temperature, take out, and during placement room temperature, it is stand-by to grind to form smalls;
3. be placed on tile by Fructus Aurantii Immaturus, Rhizoma Polygoni Paleachi, Fructus Hippophae, Herba Artemisiae Anomalae and Caulis Bambusae In Taenia, little fire dries 10-30 minute slowly, dries in the air coolly to grind to form smalls, crosses 80-120 mesh sieve (preferably 100 mesh sieves);
4. Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus are cleaned, be cut into coin-size stand-by;
5. Semen Maydis is eluriated 1-3 time, add Semen Maydis weight 8-12 water doubly, soak after 1 hour, big fire adds step 4. gains after boiling, after big fire boils 4-8 minute, be blended into cold water, turn slow fire boiling 20-40 minute, slowly stir with ferrum spoon, to be mixed when becoming thick liquid to Fructus Cucurbitae moschatae, Radix Raphani and Fructus psidii guajavae immaturus, add step 1.-3. gained smalls, fully stir into thick paste;
6. by step 5. gained thick paste at 50-70 DEG C of dry 10-18 hour, make granule, the granule be prepared into is packed according to the preparation technology of capsule and be get final product.
5. the preparation method of health-caring capsule according to claim 4, is characterized in that: 1. Os Draconis and Concha Arcae are placed in the hot water (preferably Os Draconis and Concha Arcae being placed in the hot water of 90 DEG C) of 85-95 DEG C by step.
6. the preparation method of health-caring capsule according to claim 4, is characterized in that: step 2. high temperature sterilization 2-4 minute (preferred high temperature sterilization 3 minutes).
7. the preparation method of health-caring capsule according to claim 4, is characterized in that: step 3. little fire is dried 15-25 minute (preferred little fire dries 20 minutes slowly) slowly.
8. the preparation method of health-caring capsule according to claim 4, is characterized in that: 5. step adds Semen Maydis weight 9-11 water (preferably adding the water of Semen Maydis weight 10 times) doubly.
9. the preparation method of health-caring capsule according to claim 4, is characterized in that: step after 5. big fire boils 5-7 minute, is blended into cold water, turns slow fire boiling 25-35 minute (preferred big fire boil 6 minutes after, be blended into cold water, turn slow fire boiling 30 minutes).
10. the preparation method of health-caring capsule according to claim 4, is characterized in that: step 6. thick paste, at 55-65 DEG C of dry 12-16 hour, makes granule (preferred thick paste, 60 DEG C of dryings 14 hours, makes granule).
CN201410773466.5A 2014-12-16 2014-12-16 Health capsule for treating reflux esophagitis caused by gastroduodenal dysfunction and preparation method of health capsule Pending CN104474347A (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1698818A (en) * 2005-06-09 2005-11-23 赵东科 Medicine for treating chronic stomach disease and its preparation method
CN1919331A (en) * 2006-08-22 2007-02-28 夏金陵 Chinese medicine composition for treating gastritis and preparing method thereof
CN103182065A (en) * 2013-03-27 2013-07-03 朱新华 Oral liquid for treating gastric and duodenal ulcer efficiently
CN103404756A (en) * 2013-05-27 2013-11-27 胡安然 Special diet for gastroenteritis patients
CN103638443A (en) * 2013-12-30 2014-03-19 高承香 Traditional Chinese medicine for treating oesophagitis

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1698818A (en) * 2005-06-09 2005-11-23 赵东科 Medicine for treating chronic stomach disease and its preparation method
CN1919331A (en) * 2006-08-22 2007-02-28 夏金陵 Chinese medicine composition for treating gastritis and preparing method thereof
CN103182065A (en) * 2013-03-27 2013-07-03 朱新华 Oral liquid for treating gastric and duodenal ulcer efficiently
CN103404756A (en) * 2013-05-27 2013-11-27 胡安然 Special diet for gastroenteritis patients
CN103638443A (en) * 2013-12-30 2014-03-19 高承香 Traditional Chinese medicine for treating oesophagitis

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
李玺等: "沙棘油口服液治疗反流性食管炎100例", 《陕西中医》 *
白海燕等: "橘皮竹茹汤治疗反流性食道炎", 《四川中医》 *
石桂珍等: "反流性食管炎的中医药治疗", 《内蒙古中医药》 *
裴静波: "竹茹枳实汤治疗反流性食管炎36例观察", 《浙江中医杂志》 *

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