CN104474213A - 一种用于治疗褥疮的中药膏剂及其制备方法 - Google Patents
一种用于治疗褥疮的中药膏剂及其制备方法 Download PDFInfo
- Publication number
- CN104474213A CN104474213A CN201410792717.4A CN201410792717A CN104474213A CN 104474213 A CN104474213 A CN 104474213A CN 201410792717 A CN201410792717 A CN 201410792717A CN 104474213 A CN104474213 A CN 104474213A
- Authority
- CN
- China
- Prior art keywords
- parts
- medicine
- treatment
- burn
- earns
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003814 drug Substances 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title claims description 10
- 208000004210 Pressure Ulcer Diseases 0.000 title abstract description 5
- 239000004863 Frankincense Substances 0.000 claims abstract description 18
- 208000025865 Ulcer Diseases 0.000 claims description 21
- 231100000397 ulcer Toxicity 0.000 claims description 21
- 241000283690 Bos taurus Species 0.000 claims description 17
- 241000717739 Boswellia sacra Species 0.000 claims description 17
- 239000002674 ointment Substances 0.000 claims description 17
- 239000012567 medical material Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000012153 distilled water Substances 0.000 claims description 9
- 239000000706 filtrate Substances 0.000 claims description 6
- 239000013521 mastic Substances 0.000 claims description 6
- 238000005516 engineering process Methods 0.000 claims description 5
- -1 boil 2 ~ 3 hours Substances 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 3
- 238000002156 mixing Methods 0.000 claims description 3
- 238000010298 pulverizing process Methods 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 9
- 231100000331 toxic Toxicity 0.000 abstract description 6
- 230000002588 toxic effect Effects 0.000 abstract description 6
- 240000005944 Mallotus barbatus Species 0.000 abstract description 2
- 241001170357 Veratrum mengtzeanum Species 0.000 abstract description 2
- 239000000463 material Substances 0.000 abstract 2
- 235000003717 Boswellia sacra Nutrition 0.000 abstract 1
- 240000007551 Boswellia serrata Species 0.000 abstract 1
- 235000012035 Boswellia serrata Nutrition 0.000 abstract 1
- 241000037740 Coptis chinensis Species 0.000 abstract 1
- 241000733283 Mayodendron igneum Species 0.000 abstract 1
- 239000010495 camellia oil Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 7
- 206010040943 Skin Ulcer Diseases 0.000 description 6
- 239000000796 flavoring agent Substances 0.000 description 6
- 235000019634 flavors Nutrition 0.000 description 6
- 231100000019 skin ulcer Toxicity 0.000 description 6
- 208000002193 Pain Diseases 0.000 description 5
- 230000036407 pain Effects 0.000 description 5
- 201000004624 Dermatitis Diseases 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 244000045947 parasite Species 0.000 description 3
- 206010063409 Acarodermatitis Diseases 0.000 description 2
- 241001608538 Boswellia Species 0.000 description 2
- 206010007247 Carbuncle Diseases 0.000 description 2
- 206010017553 Furuncle Diseases 0.000 description 2
- 241000447727 Scabies Species 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 230000017531 blood circulation Effects 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 208000014674 injury Diseases 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 208000005687 scabies Diseases 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 208000004371 toothache Diseases 0.000 description 2
- 230000008736 traumatic injury Effects 0.000 description 2
- 230000008673 vomiting Effects 0.000 description 2
- 206010000077 Abdominal mass Diseases 0.000 description 1
- 206010000087 Abdominal pain upper Diseases 0.000 description 1
- 208000006820 Arthralgia Diseases 0.000 description 1
- 241001090347 Bignoniaceae Species 0.000 description 1
- 206010005913 Body tinea Diseases 0.000 description 1
- 235000018062 Boswellia Nutrition 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 241000526900 Camellia oleifera Species 0.000 description 1
- 235000008495 Chrysanthemum leucanthemum Nutrition 0.000 description 1
- 244000192528 Chrysanthemum parthenium Species 0.000 description 1
- 235000000604 Chrysanthemum parthenium Nutrition 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 241000037803 Coptis deltoidea Species 0.000 description 1
- 244000247747 Coptis groenlandica Species 0.000 description 1
- 235000002991 Coptis groenlandica Nutrition 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000221079 Euphorbia <genus> Species 0.000 description 1
- 206010063560 Excessive granulation tissue Diseases 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 206010062575 Muscle contracture Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 241001529246 Platymiscium Species 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 241000218201 Ranunculaceae Species 0.000 description 1
- 206010067171 Regurgitation Diseases 0.000 description 1
- 208000028990 Skin injury Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 238000003723 Smelting Methods 0.000 description 1
- 208000033809 Suppuration Diseases 0.000 description 1
- 241001122767 Theaceae Species 0.000 description 1
- 241000159241 Toxicodendron Species 0.000 description 1
- 244000044283 Toxicodendron succedaneum Species 0.000 description 1
- 206010053476 Traumatic haemorrhage Diseases 0.000 description 1
- 208000003443 Unconsciousness Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 208000006111 contracture Diseases 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 208000001780 epistaxis Diseases 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 239000010685 fatty oil Substances 0.000 description 1
- 235000008384 feverfew Nutrition 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 235000021472 generally recognized as safe Nutrition 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 210000001126 granulation tissue Anatomy 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000021760 high fever Diseases 0.000 description 1
- 230000002061 histotrophic effect Effects 0.000 description 1
- 208000013403 hyperactivity Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 208000003243 intestinal obstruction Diseases 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000000414 obstructive effect Effects 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000000451 tissue damage Effects 0.000 description 1
- 231100000827 tissue damage Toxicity 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/32—Burseraceae (Frankincense family)
- A61K36/324—Boswellia, e.g. frankincense
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种用于治疗褥疮的中药膏剂，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、泽兰12份、红帽顶5份。临床实验证明，本发明通过选择合适的药材及其配比，达到治疗褥疮的显著功效，且安全无毒副作用。
Description
技术领域
本发明涉及一种中药，具体涉及一种用于治疗褥疮的中药膏剂及其制备方法。
背景技术
褥疮是身体局部组织长期受压，血液循环障碍，组织营养缺乏，致使皮肤失去正常功能而引起的组织破损和坏死。轻者为皮肤破损，重者可深达骨骼。褥疮是临床最常见的并发症之一，特别是糖尿病患者，一旦发生褥疮，更是雪上加霜。临床治疗方法虽多，但至今仍是医学领域的难题。对于治疗褥疮目前尚缺少公认安全有效的药物。
发明内容
本发明旨在提供一种用于治疗褥疮的中药膏剂及其制备方法，通过选择合适的药材及其配比，达到有助于褥疮患者康复的显著功效，且安全无毒副作用。
为了达到上述目的，本发明采用以下技术方案：一种用于治疗褥疮的中药膏剂，由以下重量配比的药材制备而成：乳香8～10份、茶油8～10份、黄连8～10份、火烧花8～10份、牛挣药6～8份、泽兰10～12份、红帽顶0～5份。
作为优选，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、泽兰12份、红帽顶5份。
作为优选，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、红帽顶5份。
作为优选，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、泽兰12份。
作为优选，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、泽兰12份、红帽顶5份。
一种用于治疗褥疮的中药膏剂的制备方法，包括如下步骤：（1）将黄连、火烧花、牛挣药、泽兰、红帽顶放入容器内，加入8～10 倍量的蒸馏水，浸泡5～6小时后，煮沸3～4 小时，提取；再次加入6～8倍量蒸馏水，煮沸2～3小时，提取；最后，加入4～6 倍量蒸馏水，加热煮沸1～2 小时，提取；合并三次提取液，过滤，得滤液备用；（2）将乳香研成细末放入容器内，加入茶油和少量蜂蜜，搅拌均匀，经容器密封，隔水加热15～25min，取出，得膏体备用；（3）将上述步骤（1）～（2）所制得的滤液以及膏体混合，利用现代先进的制药科技，制成粘稠状膏剂。
本发明各中药成份的药理分析如下：
乳香【来源】橄榄科乳香树属植物乳香树，以其树干皮部伤口渗出的油胶树脂入药。【性味】辛、苦，温。【功能主治】活血止痛。用于心腹诸痛，筋脉拘挛，跌打损伤，疮痈肿痛；外用消肿生肌。
茶油【来源】为山茶科植物油茶种子的脂肪油。【性味】甘，凉。【功能主治】清热化湿，杀虫解毒。治痧气腹痛，急性蛔虫阻塞性肠梗阻，疥癣，汤火伤。
黄连【来源】毛茛科植物黄连、三角叶黄连或云连的干燥根茎。【功能主治】清热燥湿，泻火解毒。用于湿热痞满，呕吐吞酸，泻痢，黄疸，高热神昏，心火亢盛，心烦不寐，血热吐衄，目赤，牙痛，消渴，痈肿疔疮；外治湿疹，湿疮，耳道流脓。
火烧花【来源】为紫葳科植物火烧花的根皮、树皮及叶。【性味】味苦，性凉。【功能主治】清火解毒，祛风利水，杀虫止痒。主治牙痛，风寒湿痹证，肢体关节肿痛，屈伸不利，疗疮痛疖脓肿，漆树过敏。
牛挣药【来源】药材基源：为百合科植物蒙自藜芦的根。【性味】辛；微苦；寒；有毒。【功能主治】散瘀止痛；敛疮杀虫。主跌打损伤；骨折；外伤出血；褥疮；疥癣。
泽兰【来源】本品为菊科植物佩兰的干燥地上部分。夏、秋二季分两次采割，除去杂质，晒干。【炮制】除去杂质，洗净，稍润，切段，晒干。【性味】辛，平。【归经】归脾、胃、肺经。【功能主治】芳香化湿，醒脾开胃，发表解暑。用于湿浊中阻，脘痞呕恶，口中甜腻，口臭，多涎，暑湿表症，头胀胸闷。
红帽顶【来源】为大戟科植物毛桐的叶。【性味】苦，寒。【功能主治】治湿疹，褥疮，背癣。
本发明与现有技术相比，具有以下有益效果：
1、本发明中药制剂对于治疗褥疮治愈率极高且安全无毒副作用，并可预防相关并发症。配方药材之间配伍严谨，不仅充分利用药物配伍后所产生的协同增效作用，而且避免了药物作用的互相拮杭而抵销或消弱原有的功效，更加注意选用能减轻或消除药物的烈性或毒副作用的药物配伍应用，坚决避免了药物相互配伍产生毒性反应或强烈的副作用。通过科学配伍，不仅在病情复杂，瞬息万变的情况下，本发明不仅能有效组织实施合理医治，使其达到药至病除，而且对于防止疾病传变、内侵脏腑还有较好的预防作用，在临床运用上很有价值。
、本发明中药制剂选用优质中药材制成，所选药材配伍相宜，符合中医药及现代医学研究理论，并利用现代医药制药技术制成，安全无毒副作用，达到标本兼治的目的，值得临床推广应用。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
实施例1
称取：乳香10克、茶油10克、黄连10克、火烧花10克、牛挣药8克、泽兰12克、红帽顶5克。按如下步骤：（1）将黄连、火烧花、牛挣药、泽兰、红帽顶放入容器内，加入8～10 倍量的蒸馏水，浸泡5～6小时后，煮沸3～4 小时，提取；再次加入6～8倍量蒸馏水，煮沸2～3小时，提取；最后，加入4～6 倍量蒸馏水，加热煮沸1～2 小时，提取；合并三次提取液，过滤，得滤液备用；（2）将乳香研成细末放入容器内，加入茶油和少量蜂蜜，搅拌均匀，经容器密封，隔水加热15～25min，取出，得膏体备用；（3）将上述步骤（1）～（2）所制得的滤液以及膏体混合，利用现代先进的制药科技，制成粘稠状膏剂。
用法用量：外用，每日2次，每次1剂，均匀敷于疮面。
实施例2
称取：乳香10克、茶油10克、黄连10克、火烧花10克、牛挣药8克、泽兰12克、红帽顶5克。
本实施例的制备方法、用法用量与实施例1相同。
实施例3
称取：乳香10克、茶油10克、黄连10克、火烧花10克、牛挣药8克、泽兰12克、红帽顶5克。
本实施例的制备方法、用法用量与实施例1相同。
临床资料：
1、病例选择：
选择2013年以来在我院诊治的已生褥疮患者128例临床观察，临床症状均符合褥疮所列标准。病人随机分成治疗组和对照组两组，治疗组64例，对照组64例。治疗组和对照组两组病例的病程、症状轻重程度基本一致，无显著差异，具有可比性。
、药物选择：
治疗组用本发明实施例1所制得的中药膏剂，外用，每日2次，每次1剂，均匀敷于疮面。7天为1个疗程。
对照组在冲洗疡面2次，清除脓痴后，将湿润烧伤膏挤压到疡面上，厚度均为1-2毫米。
连续冶疗2个疗程，对比两组疗效。
、疗效判定：
（1）治愈：治疗1周后褥疮溃烂部位干燥，无外渗液，疮面呈粉红色，有明显结痴，溃疡愈合。
（2）好转：2周后疼痛减轻，疮面出现新生肉芽组织，范围明显缩小。
（3）未愈：2周后疮面无明显改善。
、结果：
选用本发明实施例1中药膏剂的治疗组中，治愈48例，好转14例，未愈2例，治愈率75%，总有效率96.8%。
对照组中治愈23例，好转10例，未愈31例，治愈率35.9%，总有效率51.5%。
以上结果显示，治疗组的治愈率和总有效率明显高于对照组。
显然，本发明的上述实施例仅仅是为清楚地说明本发明所作的举例，而并非是对本发明的实施方式的限定。对于所属领域的普通技术人员来说，在上述说明的基础上还可以做出其它不同形式的变化或变动。这里无法对所有的实施方式予以穷举。凡是属于本发明的技术方案所引伸出的显而易见的变化或变动仍处于本发明的保护范围之列。
Claims (6)
1.一种用于治疗褥疮的中药膏剂，其特征在于，由以下重量配比的药材制备而成：乳香8～10份、茶油8～10份、黄连8～10份、火烧花8～10份、牛挣药6～8份、泽兰10～12份、红帽顶0～5份。
2.根据权利要求1所述的一种用于治疗褥疮的中药膏剂，其特征在于，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、泽兰12份、红帽顶5份。
3.根据权利要求1所述的一种用于治疗褥疮的中药膏剂，其特征在于，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、红帽顶5份。
4.根据权利要求1所述的一种用于治疗褥疮的中药膏剂，其特征在于，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、泽兰12份。
5.根据权利要求1所述的一种用于治疗褥疮的中药膏剂，其特征在于，由以下重量配比的药材制备而成：乳香10份、茶油10份、黄连10份、火烧花10份、牛挣药8份、泽兰12份、红帽顶5份。
6.一种用于治疗褥疮的中药膏剂的制备方法，其特征在于，包括如下步骤：（1）将黄连、火烧花、牛挣药、泽兰、红帽顶放入容器内，加入8～10 倍量的蒸馏水，浸泡5～6小时后，煮沸3～4 小时，提取；再次加入6～8倍量蒸馏水，煮沸2～3小时，提取；最后，加入4～6 倍量蒸馏水，加热煮沸1～2 小时，提取；合并三次提取液，过滤，得滤液备用；（2）将乳香研成细末放入容器内，加入茶油和少量蜂蜜，搅拌均匀，经容器密封，隔水加热15～25min，取出，得膏体备用；（3）将上述步骤（1）～（2）所制得的滤液以及膏体混合，利用现代先进的制药科技，制成粘稠状膏剂。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410792717.4A CN104474213A (zh) | 2014-12-19 | 2014-12-19 | 一种用于治疗褥疮的中药膏剂及其制备方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410792717.4A CN104474213A (zh) | 2014-12-19 | 2014-12-19 | 一种用于治疗褥疮的中药膏剂及其制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104474213A true CN104474213A (zh) | 2015-04-01 |
Family
ID=52748914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410792717.4A Pending CN104474213A (zh) | 2014-12-19 | 2014-12-19 | 一种用于治疗褥疮的中药膏剂及其制备方法 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104474213A (zh) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102416089A (zh) * | 2011-11-18 | 2012-04-18 | 韩传瑞 | 一种外敷中药膏及其制备方法 |
| CN102614355A (zh) * | 2012-03-27 | 2012-08-01 | 孙静 | 一种治疗褥疮的药物组合物 |
-
2014
- 2014-12-19 CN CN201410792717.4A patent/CN104474213A/zh active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102416089A (zh) * | 2011-11-18 | 2012-04-18 | 韩传瑞 | 一种外敷中药膏及其制备方法 |
| CN102614355A (zh) * | 2012-03-27 | 2012-08-01 | 孙静 | 一种治疗褥疮的药物组合物 |
Non-Patent Citations (2)
| Title |
|---|
| 刘毅等: "傣医药治疗皮肤病拾萃", 《中国民族医药杂志》 * |
| 曹社国: "中药治疗严重褥疮的临床观察", 《中成药研究》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101804166B (zh) | 一种治疗小儿皮炎湿疹的中药组合物 | |
| CN103393953B (zh) | 一种促进术后伤口愈合的中药药膏及制备方法 | |
| CN102327478A (zh) | 一种治疗烧烫伤的药物组合物及其制备方法 | |
| CN101791378B (zh) | 一种用于伤口止血、抗炎、生肌的中药制剂 | |
| CN105662996A (zh) | 治疗月经相关性痤疮的中药面膜 | |
| CN105168650A (zh) | 一种用于普外科手术麻醉止痛的中药组合物 | |
| CN104288255A (zh) | 治疗重症急性胰腺炎的中药制剂 | |
| CN103417781A (zh) | 一种治疗外科伤口的中药 | |
| CN102961633B (zh) | 一种用于治疗产后风湿病的制剂 | |
| CN105535331A (zh) | 一种治疗宫颈糜烂的外用药膏及其制备方法 | |
| CN102284006B (zh) | 一种治疗褥疮及烧烫创伤的外用膏剂 | |
| CN104971312A (zh) | 一种专治牛皮癣的外用药物 | |
| CN104623304A (zh) | 一种治疗湿热毒蕴型慢性皮肤溃疡的洗剂及其制备方法 | |
| CN104623040A (zh) | 一种用于创口杀菌消炎的护理组合物及其制备方法 | |
| CN104474213A (zh) | 一种用于治疗褥疮的中药膏剂及其制备方法 | |
| CN105125928A (zh) | 一种治疗烫伤的外用膏剂及制备方法 | |
| CN106267075A (zh) | 一种用于治疗强直性脊柱炎的中药胶囊 | |
| CN106214993A (zh) | 一种治疗风热型膝关节炎的药饼及其制备方法 | |
| CN105560582A (zh) | 治疗冻疮的消肿止痒药膏及制法 | |
| CN105030975A (zh) | 一种治疗粘连性肠梗阻的药物及其制备方法 | |
| CN104815077A (zh) | 一种检验科外伤杀菌消炎物质及其制备方法 | |
| CN104491537A (zh) | 一种治疗风湿性心脏病的中药组合物 | |
| CN104435556A (zh) | 一种用于治疗皮肤溃疡的中药胶囊及其制备方法 | |
| CN104225343A (zh) | 治疗尿路感染的中药制剂及制法 | |
| CN103721028A (zh) | 一种治疗心绞痛的药物及制备方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150401 |