CN1044491C - Internal and external double-circular current fermentation can - Google Patents

Internal and external double-circular current fermentation can Download PDF

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Publication number
CN1044491C
CN1044491C CN93117329A CN93117329A CN1044491C CN 1044491 C CN1044491 C CN 1044491C CN 93117329 A CN93117329 A CN 93117329A CN 93117329 A CN93117329 A CN 93117329A CN 1044491 C CN1044491 C CN 1044491C
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mixing tank
fluid
channel
downtake
upcast
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CN1099795A (en
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赵柏松
洪中元
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C12M29/08—Air lift
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/24—Recirculation of gas
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/26—Conditioning fluids entering or exiting the reaction vessel

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  • General Engineering & Computer Science (AREA)
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Abstract

The present invention relates to a new ventilation fermentation tank in a chemical machinery field. In the new ventilation fermentation tank, the effective functions of a static mixer and a venturi pipe are added on the basis of a gas lifting type fermentation tank, the movement of fluid inner circulation is formed between a rising pipe and a lowering pipe, and in the movement of fluid inner circulation, fluid moves from bottom to top in the rising pipe and moves from top to bottom in the lowering pipe. The fluid is sprayed into the static mixer by a mixing fluid distributor through a circulation pump and the venturi pipe from a material sucking pipe to form a fluid outer circulation system. After the present invention is used, fermentation liquid has the advantages of uniform mixing effect, small bubble and high oxygen dissolving level. The present invention enhances convective circulation and has the stable fermentation, and the present invention can improve quality and can also enhance output. The present invention has low total energy consumption, and the present invention can be used for the technical reformation of the old tank.

Description

Internal and external double-circular current fermentation can
The invention belongs to chemical machinery field, what relate to is a kind of air blow tank of fermentation engineering conversion unit, specifically a kind of internal and external double-circular current fermentation can.
The fermentor tank kind of chemical field use at present is a lot, as stir aeration type fermentor tank and airlift fermentor, and the latter compares with the former, concrete structure is simple, good airproof performance helps preventing microbiological contamination and to advantages such as the big microbial fermentation energy expenditure of air consumption are low.But there are some shortcomings in airlift fermentor, as equipment aspect ratio big (8～17), and factory building height, the big (0.35～0.45m of aseptic compressed air consumption 3/ m 3, min), the fermented liquid mass transfer ability higher to viscosity is low, the regulating measure of equipment when operation operating mode operation is narrow, wayward etc.
Advantages such as Venturi tube (abbreviation Venturi meter) is extensive in industrial application, and as the Venturi meter fermentor tank of fermentation industry, it has oxygen uptake efficient height, and gas, liquid, solid (microorganism) three-phase mixes, and equipment is simple.Shortcoming is that the ratio (volume suction coefficient) of gas soakage and liquid flow rate is lower, and pump flow is big, and the microbial fermentation big to oxygen-consumption is not suitable for.
Line mixer (static mixer is hereinafter to be referred as mixing tank) is a kind of mixing tank that does not have mechanical operating part.It is that several left-handed and dextral screw elements are arranged, and interconnective both sides one-tenth is staggered for 90 ° and forms in pipeline.It is simple and compact for structure, good mixing effect, and the maintenance expense is low.It comes from the Kennics company of the U.S., and this product that the said firm produced in 1969 has been subjected to user's very big welcome when the demonstration of tame factory more than 100 is on probation.(changing mechanical book series " stirring and whipping appts " P8)
Internal and external double-circular current fermentation can of the present invention is airlift fermentor, Venturi meter and line mixer three's a combination, the objective of the invention is to bring into play air lift type and the wrong pipe of literary composition fermentor tank separately advantage the time, overcomes the shortcoming of its existence.
By internal and external double-circular current fermentation can proposed by the invention, it is on the basis of airlift fermentor, dissolve in the effective efficiency of mixing tank and Venturi meter, in the upcast at tank body middle part, downtake is housed, the mixing tank that screw element is formed is housed in the ringwise circular channel of the cross section that forms between upcast and the downtake, material sucking pipes is equipped with in the downtake lower end, and the material sucking pipes the other end links to each other with the pump inlet end, and the outlet of circulating pump end links to each other with Venturi meter.The mixed stream sparger of upcast bottom is led in the outlet of Venturi meter, to implement the injection to the orlop mixing tank.
Fig. 1 is a structural representation of the present invention.
Fig. 2 is the venturi tube structure synoptic diagram.
Fig. 3 is the dextral screw element structural representation in a line mixer left side.
Embodiment is explained in detail invention below in conjunction with accompanying drawing.
The middle portion of tank body is a upcast 2, downtake 1 is positioned at the central authorities of upcast 2 pipes, two ends communicate with upcast, both are circular concentric in the cross section, form the circular channel of ring-shaped section and ring-shaped between upcast and the downtake 1, this circular channel constitutes the fluid inner cycle channel with downtake, the ratio of the annular cross-sectional area Ar between downtake sectional area Ad and upcast and the downtake: Ad: Ar=0.2～0.7.Between upcast 2 and downtake 1 in the circular channel, mixing tank 3 is housed, mixing tank is provided with layer 2-4, present embodiment is established 4 layers, every layer is made of sealed screw element 16 around the 4-8, spirality channel between each screw element 16 and the sealing member is the fluid channel of every layer of mixing tank, the screw element rotation direction of every layer of mixing tank is identical, the channel center of adjacent two layers mixing tank is staggered by half of every layer of mixing tank adjacency channel center angle α, shown in the A-A and B-B sectional view of Fig. 1, every layer of mixing tank of present embodiment established 8 screw elements.Be provided with watercooling jacket 4 between upcast 2 and every layer of mixing tank 3, watercooling jacket 4 has pipeline to connect outward.Screw element 16 has left-handed and two kinds of rotation directions of dextrorotation, and aspect ratio is about 1.5, and the opposite and part limit of rotation direction was 90 degree and arranges when the screw element of adjacent two layers mixing tank was provided with.Be provided with vortex diffuser casing 5 between the adjacent two layers mixing tank, its highly be screw element 1-1.2 doubly.
Recycle pump 9 entrance ends are connected with material sucking pipes 11, for the internal recycle that do not disturb fermentor tank with avoid inspiration to contain the fermented liquid of precipitated impurities, and the slightly high center, downtake lower end in the suction nozzle of material sucking pipes 11 is arranged on jar.The exit end of recycle pump 9 communicates with Venturi meter 8, the Venturi meter upper end connects inlet pipe 6 by aspirating chamber 13, the Venturi meter opening for feed is a convergent nozzle 12, exit portion is mixing section 14 and diffusor 15, the mixed stream sparger 7 that connects the lower end, circular channel between upcast and downtake again is to implement upwards to spray to mixing tank.Material sucking pipes, recycle pump, Venturi meter constitute fluidic outer circulation passage.
Internal and external double-circular current principle of work of the present invention is as follows:
After fermented liquid being pressed into the convergent nozzle 12 of Venturi meter when recycle pump 9, because flow rate of liquid increases, make aspirating chamber 13 form vacuum, the aseptic compressed air of inlet pipe 6 inputs sucked, and be dispersed into tiny bubble in mixing section 14 with fermented liquid uniform mixing, dissolved oxygen.When Re=6 * 10 are counted in the heavily promise of jet exit section fermented liquid 4When above, the specific absorption of gas is the highest.The gas-liquid two-phase intimate mixing fluid that mixing section 14 comes out just by the mixing tank fluid distribution, is ejected facing to mixing tank by the upcast bottom behind diffusor 15.Formed fluid external circulating system of the present invention thus.Usually the rate of air sucked in required of Venturi meter should be 1.2 times of the highest air consumption of microbial metabolism fermenting process, for the big microbial fermentation of air consumption, when the Venturi meter rate of air sucked in required can not satisfy, as improve the restricted words of air compression ratio, can set up the 10 extra tonifying Qi of an air-distributor again and solve, the tonifying Qi circuit is shown in double dotted line among Fig. 1.
After mixed stream sprayed into upcast, just the density than downtake was little for the fermented liquid in the upcast, and under the promotion of density difference, the fermented liquid of downtake lower end will flow to upcast; In addition, when the upcast bubble rises,, make the fermented liquid on upcast top be pushed into the upper port of downtake by the drag force effect that buoyancy causes to liquid, thus form upcast from bottom to top with the top-down fluid of downtake in the road cyclic motion.
When fluid enters mixing tank, there are two kinds of hybrid modes to carry out simultaneously: axially shunting action mode and radially mixing effect mode.The former cuts into two stocks stream with fluid, and the displacement rising, plays bubble crushing and stops the bubbling polymerization effect; The latter makes fluid produce eddying motion, and utilizes the opposite and part limit of two layers of mixing tank screw element rotation direction to be mutually 90 ° of structure arranged, and its sense of rotation is replacing alternately, thereby has greatly increased the fluidic perturbation.When fluidic reynolds number Re=100, fluidic flows and just is in stable turbulence state, impel the further uniform mixing of gas, liquid, solid (microorganism) three, the heat distribution that fermentation is produced is tending towards even, and fluid is constantly exchanged between mixing tank wall and runner center, thereby strengthened mass transfer process, improved biography oxygen ability.
The effect of vortex diffuser casing is: utilize the scattering nature of viscous fluid mesoscale eddies, each eddy field that allows the vorticity that comes out in the mixing tank be not quite similar, enter this section after the strong place of vortex carry vortex to weak place, till vorticity equates.And make each vortex diffuse into a maelstrom, and when entering the upper strata mixing tank, because the perturbation that swirl direction changes forms the intensive turbulent flow and mixes at staggered α/2 degree angular ranges.
The present invention is on the basis of airlift fermentor, owing to introduced the shunting of blender and radially mixed function, viscous fluid mesoscale eddies diffusivity, and the flat function of high dissolved air water of Venturi tube, its resultant effect improves greatly, is in particular in:
1, fluid is between the levels of fermentation tank, Internal and external cycle, and fermentation tank Strengthened shearing and convection action between inside and outside, the stable strong row of turbulent flow, make gas, liquid, Gu the three-phase contact interface constantly obtains upgrading, and mixes very even. Gas is through Wen Pipe and blender are again and again broken, and bubble diameter is tiny of the foam degree, gas, liquid The total contact area of two-phase increases.
2, because the rotation direction of eddying motion is alternately changed, and bubble institute's distance of walking in fermented liquid increases, the residence time prolongs, molten gas is abundant, and the aspect ratio that makes fermentor tank reduces to stir the aeration type fermentor tank the same, helps old jar technological transformation, reduces new jar manufacturing cost.
3, the present invention is the internal and external double-circular border, has strengthened convection circulation, gas---liquid mass transfer (molten gas) is Gu and liquid---mass transfer (outer room in the microorganism) level height, fermenting process is stable, can good quality and high output.
4, the present invention sprays working medium, and motivating force is big, and flow is little, speed is low, and air consumption reduces 50%.In addition because downtake sectional area ratio upcast is little, fluid when internal recycle the rate of flow of fluid in the downtake greater than upcast, more bubble is introduced in the downtake, make fermentation total gas holdup raising at night, not only be beneficial to dissolved oxygen, and reduced fluid density, recycle pump shaft power is descended, therefore, total power consumption of the present invention is compared all little with gas lift with stirring aeration type fermentor tank.

Claims (5)

1, a kind of air blow tank of chemical machinery field---internal and external double-circular current fermentation can, the middle portion of tank body is a upcast, central authorities in the upcast pipe are provided with downtake, forming cross section between upcast and the downtake is the annular circular channel, and described circular channel constitutes the fluid inner cycle channel with downtake; The downtake cross-sectional area is 0.2～0.7 with the ratio of the cross-sectional area of circular channel, it is characterized in that being equipped with in the described circular channel 2～4 layers of mixing tank, every layer of mixing tank is made of sealed screw element around 4～8, spirality channel between each screw element and the sealing member is the fluid channel of every layer of mixing tank, be provided with the vortex diffuser casing between the adjacent two layers mixing tank, it highly is 1～1.2 times of screw element; Described fermentor tank also comprises a fluid outer circulation passage of being made up of material sucking pipes, recycle pump, Venturi tube, the suction nozzle of material sucking pipes puts in the jar, and be positioned at the lower end of downtake, the other end of material sucking pipes links to each other with pump inlet, outlet of circulating pump links to each other with the opening for feed of Venturi tube, the mixed stream sparger of the lower end, circular channel in the outlet of Venturi tube and the jar between upcast and downtake links to each other, and links to each other with inlet pipe by aspirating chamber in the middle of the Venturi tube.
2, by the described inner and outer ring current fermentation can of claim 1, it is characterized in that between upcast and every layer of mixing tank, being provided with watercooling jacket, and have pipeline to connect outward.
3, by claim 1 or 2 described internal and external double-circular current fermentation cans, it is characterized in that the screw element rotation direction of every layer of mixing tank is identical.
4,, it is characterized in that the channel center in the adjacent two layers mixing tank is staggered by half of the center angle α of every layer of mixing tank adjacency channel by the described internal and external double-circular current fermentation can of claim 3.
5,, it is characterized in that the screw element rotation direction in the adjacent two layers mixing tank is opposite, and the part limit is mutually 90 degree arrangements by the described internal and external double-circular current fermentation can of claim 4.
CN93117329A 1993-09-01 1993-09-01 Internal and external double-circular current fermentation can Expired - Fee Related CN1044491C (en)

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Application Number Priority Date Filing Date Title
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CN1044491C true CN1044491C (en) 1999-08-04

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CN102250752B (en) * 2011-04-21 2013-09-04 吕长山 Independent air lifting dual circulation fermentation tank
CN102586095B (en) * 2012-03-01 2013-03-27 许鉴峰 Gas stripping convective circulation anaerobic digestion reactor
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CN105505749A (en) * 2016-03-04 2016-04-20 江南大学 Air-liquid dual injection type airlift loop reactor
ES2914725T3 (en) 2017-03-10 2022-06-15 Dow Global Technologies Llc Aerobic fermentation systems and methods
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CN113491977A (en) * 2020-03-19 2021-10-12 李茂正 Improved structure of stirring tank equipment
CN112372865A (en) * 2020-09-29 2021-02-19 镇江瑞昊工程塑料有限公司 Plastic triaxial color mixing device
CN114350480B (en) * 2022-01-12 2023-12-19 万华化学(四川)有限公司 Double-circulation bubbling fermentation tank and method for preparing lactic acid by fermentation
CN117801923B (en) * 2023-06-28 2024-07-23 上海拜高乐生物技术有限公司 Microbial fermentation system for escherichia coli

Citations (2)

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Publication number Priority date Publication date Assignee Title
US418362A (en) * 1889-12-31 Island
CN2102931U (en) * 1991-09-25 1992-04-29 宝鸡制药机械厂 Air-lift double circulation fermentation reactor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US418362A (en) * 1889-12-31 Island
CN2102931U (en) * 1991-09-25 1992-04-29 宝鸡制药机械厂 Air-lift double circulation fermentation reactor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
《化工机械》第19卷第6期 1992.11.30 马晓建，方维藩"带有静态混合元件的管壳式换热器的应用" *

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