CN104435939A - Traditional Chinese medicine preparation for treating wind-warm lung-heat disease - Google Patents

Traditional Chinese medicine preparation for treating wind-warm lung-heat disease Download PDF

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CN104435939A
CN104435939A CN201410691377.6A CN201410691377A CN104435939A CN 104435939 A CN104435939 A CN 104435939A CN 201410691377 A CN201410691377 A CN 201410691377A CN 104435939 A CN104435939 A CN 104435939A
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radix
chinese medicine
medicine preparation
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王利华
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968Ophiopogon (Lilyturf)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a traditional Chinese medicine preparation for treating the wind-warm lung-heat disease. The traditional Chinese medicine preparation is prepared from the following medicinal materials in parts by weight: 10 parts of flos farfarae, 10 parts of aster, 8 parts of radix stemonae, 8 parts of semen lepidii powder, 15 parts of rhizoma phragmitis, 15 parts of radix rehmanniae recens, 12 parts of radix ophiopogonis, 6 parts of mint, 5 parts of tragacanth, 6 parts of chrysoidine, 8 parts of Chinese knotweed root, 6 parts of folium et cacumen murryvae, 8 parts of polygonum viviparum, and 4 parts of carbonized hair. Clinical experiments prove that through the selection of the appropriate medicinal materials and the appropriate ratio of the medicinal materials, the traditional Chinese medicine preparation has the effects of moistening lung and descending qi, dispersing blood stasis and promoting the secretion of saliva or body fluid, and strengthening body resistance and suppressing pathogenic factors, is extremely high in curative ratio of the wind-warm lung-heat disease, is safe, has no toxic or side effects, can prevent related complications to achieve the purpose of treating both symptoms and root causes, and is worthy of clinical popularization and application.

Description

A kind of Chinese medicine preparation for the treatment of wind-warm lung-heat disease
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of wind-warm lung-heat disease.
Background technology
Wind-warm lung-heat disease violates lung, hot Kui lung qi by wind heat pathogenic factor, and caused by impairment of purifying function of the lung, to generate heat, cough, chest pain etc. are main clinical manifestation.Be equivalent to Acute Lung inflammatory lesion.This disease with fever of the body, cough, excessive thirst, or accompanies out of breath, chest pain to be primary symptom.The visible high fever of sick severe one, Blushing, dysphoria, the quiet language of coma, or the disease such as extreme cold of the limbs.Winter and spring is more.Have the advantages that onset is anxious, the change of disease is fast, the course of disease is short.Clinically to the treatment of this disease, generally based on the traditional Chinese medical science, but most of prescription drug effect does not show, and the therapeutic effect for wind-warm lung-heat disease is not remarkable.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine preparation for the treatment of wind-warm lung-heat disease, it selects medical material compatibility suitable, meet Chinese medicine and modern medicine study theory, there is nourishing the lung to keep the adverse QI downward, dissipating blood stasis promote the production of body fluid, effect of Fuzheng Yiliu heresy, high and the safe without toxic side effect for the treatment of wind-warm lung-heat disease cure rate, and related complication can be prevented to reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
In order to achieve the above object, the present invention is by the following technical solutions: a kind of Chinese medicine preparation for the treatment of wind-warm lung-heat disease, is prepared from by the medical material of following weight proportion: Flos Farfarae 9 ~ 11 parts, Radix Asteris 9 ~ 11 parts, the Radix Stemonae 7 ~ 9 parts, 7 ~ 9 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 14 ~ 16 parts, Radix Rehmanniae 14 ~ 16 parts, Radix Ophiopogonis 11 ~ 13 parts, Herba Menthae 5 ~ 7 parts, tragacanth 4 ~ 6 parts, Exocarpium Citri Rubrum 5 ~ 7 parts, Radix Polygoni Chinensis 7 ~ 9 parts, Folium Et Cacumen Murrayae 5 ~ 7 parts, Polygonum viviparum L. 5 ~ 9 parts, Crinis Carbonisatus 0 ~ 5 part.
As preferably, be prepared from by the medical material of following weight proportion: Flos Farfarae 9 ~ 11 parts, Radix Asteris 9 ~ 11 parts, the Radix Stemonae 7 ~ 9 parts, 7 ~ 9 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 14 ~ 16 parts, Radix Rehmanniae 14 ~ 16 parts, Radix Ophiopogonis 11 ~ 13 parts, Herba Menthae 5 ~ 7 parts, tragacanth 4 ~ 6 parts, Exocarpium Citri Rubrum 5 ~ 7 parts, Radix Polygoni Chinensis 7 ~ 9 parts, Folium Et Cacumen Murrayae 5 ~ 7 parts, Polygonum viviparum L. 5 ~ 9 parts.
As preferably, be prepared from by the medical material of following weight proportion: Flos Farfarae 9 ~ 11 parts, Radix Asteris 9 ~ 11 parts, the Radix Stemonae 7 ~ 9 parts, 7 ~ 9 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 14 ~ 16 parts, Radix Rehmanniae 14 ~ 16 parts, Radix Ophiopogonis 11 ~ 13 parts, Herba Menthae 5 ~ 7 parts, tragacanth 4 ~ 6 parts, Exocarpium Citri Rubrum 5 ~ 7 parts, Radix Polygoni Chinensis 7 ~ 9 parts, Folium Et Cacumen Murrayae 5 ~ 7 parts, Polygonum viviparum L. 7 ~ 9 parts, Crinis Carbonisatus 3 ~ 5 parts.
As preferably, be prepared from by the medical material of following weight proportion: Flos Farfarae 10 ~ 11 parts, Radix Asteris 10 ~ 11 parts, the Radix Stemonae 8 ~ 9 parts, 8 ~ 9 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 15 ~ 16 parts, Radix Rehmanniae 15 ~ 16 parts, Radix Ophiopogonis 12 ~ 13 parts, Herba Menthae 6 ~ 7 parts, tragacanth 5 ~ 6 parts, Exocarpium Citri Rubrum 6 ~ 7 parts, Radix Polygoni Chinensis 8 ~ 9 parts, Folium Et Cacumen Murrayae 6 ~ 7 parts, Polygonum viviparum L. 8 ~ 9 parts, Crinis Carbonisatus 4 ~ 5 parts.
As preferably, be prepared from by the medical material of following weight proportion: Flos Farfarae 10 parts, Radix Asteris 10 parts, the Radix Stemonae 8 parts, 8 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 15 parts, Radix Rehmanniae 15 parts, Radix Ophiopogonis 12 parts, Herba Menthae 6 parts, tragacanth 5 parts, Exocarpium Citri Rubrum 6 parts, Radix Polygoni Chinensis 8 parts, Folium Et Cacumen Murrayae 6 parts, Polygonum viviparum L. 8 parts, Crinis Carbonisatus 4 parts.
A kind of preparation method for the treatment of the Chinese medicine preparation of wind-warm lung-heat disease, comprise the steps: that Flos Farfarae, Radix Asteris, the Radix Stemonae, Rhizoma Phragmitis, Radix Rehmanniae, Radix Ophiopogonis, Herba Menthae, Exocarpium Citri Rubrum, Radix Polygoni Chinensis, Folium Et Cacumen Murrayae, Polygonum viviparum L. are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) tragacanth, Semen Lepidii (Semen Descurainiae) powder, Crinis Carbonisatus are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of wind-warm lung-heat disease of the present invention.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Flos Farfarae [source] this product is the dry flower of feverfew coltsfoot.[nature and flavor] pungent, micro-hardship, temperature.[return through] returns lung meridian.[function cures mainly] nourishing the lung to keep the adverse QI downward, relieving cough and resolving phlegm.Cough for new chronic cough, dyspnea and cough with excessive sputum, chronic cough hemoptysis.
Radix Asteris [source] this product is the dry root and rhizome of feverfew Radix Asteris.[nature and flavor] are pungent, bitter, temperature.[return through] returns lung meridian.[function cures mainly] nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Breath with cough for abundant expectoration, new chronic cough is coughed, chronic cough hemoptysis.
The Radix Stemonae [source] this product is the dried root of Stemonaceae plant Radix Stemonae.[nature and flavor] are sweet, bitter, tepor.[return through] returns lung meridian.Slightly poisonous.The cough-relieving of [function cures mainly] nourishing the lung to keep the adverse QI downward, parasite killing.Cough for new chronic cough, pulmonary tuberculosis cough, pertussis; Outer for head louse, body louse, enterobiasis, pudendal pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.For deficiency of YIN chronic cough.
Rhizoma Phragmitis [source] this product is the fresh of grass phragmites communis or dry rhizome.[nature and flavor] are sweet, cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] clearing away heat and promoting production of body fluid, relieving restlessness, preventing or arresting vomiting, diuresis.For calentura excessive thirst, gastric heat is vomitted the sound of vomiting, cough due to lung-heat, lung abscess vomiting pus, the puckery pain of pyretic stranguria.
Radix Rehmanniae [source] this product is the fresh of scrophulariaceae rehmannia glutinosa plant or dried root.[nature and flavor] Radix Rehmanniae: sweet, cold.[return through] GUIXIN, liver, kidney channel.[function cures mainly] clearing away heat and cooling blood, yin nourishing, promotes the production of body fluid.For calentura crimson tongue excessive thirst, yin asthenia generating intrinsic heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat is quenched one's thirst, and spits blood, and epistaxis sends out speckle dermexanthesis.
Radix Ophiopogonis [source] this product is the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf).[nature and flavor] are sweet, and micro-hardship, is slightly cold.[return through] GUIXIN, lung, stomach warp.[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
The dry aerial parts of Herba Menthae [source] Labiatae mint Herba Menthae.[nature and flavor] are pungent, cool.[return through] returns lung, Liver Channel.[function cures mainly] dispelling wind-heat.Refresh oneself, rash.For anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat, aphtha, rubella, measles, breast the side of body feeling of distension and oppression.
The outer RED sector that Exocarpium Citri Rubrum [source] is the peel of the multiple Fructus Citri tangerinae classes such as rutaceae tangerine produced in fujian province or Zhu's Fructus Citri tangerinae.[nature and flavor] are pungent; Bitter; Temperature.[return through] bladder; Small intestinal; Lung; Spleen; Large intestine; Stomach warp.[function cures mainly] cold expelling dampness; Activating QI to eliminate phlegm; Alleviating distention in middle-JIAO stomach invigorating.Main cough due to wind and cold; Abundant expectoration QI rising in reverse order; Nausea and vomiting; Breast gastral cavity painful abdominal mass is swollen.
The root of Radix Polygoni Chinensis [source] polygonaceae plant Herb Polygoni Chinensis.[nature and flavor] are pungent; Sweet; Property is put down.[function cures mainly] invigorating spleen and kidney; Pancake liver-yang; Heat-clearing and toxic substances removing; Promoting blood circulation and detumescence.Main body void is weak; Hiccough and deaf; The vertigo; Leucorrhea; Acute mastitis; Lung abscess.
Folium Et Cacumen Murrayae [source] this product is dried leaves and the band leaf twig of rutaceae Folium Et Cacumen Murrayae and Murraya paniculata (L.) Jack..[nature and flavor] pungent, micro-hardship, temperature; Slightly poisonous.[function cures mainly] promoting the circulation of QI to relieve pain, promoting blood circulation to remove blood stasis.For stomachache, rheumatic arthralgia; External treatment is had a toothache, tumbling and swelling, worm venom.
Polygonum viviparum L. [source] polygonaceae plant Polygonum viviparum L., is used as medicine with root stock.Autumn excavates, clean dry for subsequent use.[nature and flavor] are bitter, puckery, cool.[function cures mainly] heat-clearing and toxic substances removing, dissipating blood stasis stops blooding.For tonsillitis, pharyngolaryngitis, enteritis, dysentery, leucorrhea, metrorrhagia, has blood in stool; Traumatic injury is controlled in external, carbuncle furuncle and phyma poison, traumatic hemorrhage.[usage and dosage] 2 ~ 5 money.
Crinis Carbonisatus [source] this product is the carbide that Crinis Carbonisatus is made.[nature and flavor] are bitter, flat.[return through] returns liver, stomach warp.[function cures mainly] stops blooding, blood stasis dispelling.For spitting blood, spitting of blood, epistaxis, hematuria, metrostaxis, traumatic hemorrhage.
Tragacanth [source] is leguminous plant Calculus Bovis from Northwest of China stilbene and the glue fat belonging to his kind of plant together.[nature and flavor] are flat, partially wet, lightly seasoned.[function cures mainly] corrects the evil of hundred tastes, raw moistening lung, cough-relieving, hemostasis, sore throat relieving profit larynx, tonneau urine, and antiinflammatory is healed skin ulcer.Cure mainly dryness and partially contain caused various diseases, as dryness of the lung dry cough, dry laryngopharynx, hoarseness, intestinal ulcer, urethra skin infection, burning sensation during urination.
Semen Lepidii (Semen Descurainiae) powder [source] this product is the dry mature seed of crucifer Lepidium sativum L..[nature and flavor] are pungent, bitter, Great Cold.[return through] returns lung, urinary bladder channel.[function cures mainly] eliminating pathogen from the lung for relieving asthma, line water detumescence.Stop up lung for sputum, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium, must not put down sleeping, and ascites pleural fluid swells, dysuria; Pulmonary heart disease edema.
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention has nourishing the lung to keep the adverse QI downward, dissipating blood stasis promotes the production of body fluid, effect of Fuzheng Yiliu heresy, the high and safe without toxic side effect for the treatment of wind-warm lung-heat disease cure rate.Wherein: Flos Farfarae, Radix Asteris, Radix Stemonae nourishing the lung to keep the adverse QI downward in side, and mutually help benefit between Rhizoma Phragmitis, Radix Rehmanniae, Radix Ophiopogonis, Herba Menthae, Exocarpium Citri Rubrum, Radix Polygoni Chinensis, Folium Et Cacumen Murrayae, Polygonum viviparum L., use Crinis Carbonisatus, tragacanth, Semen Lepidii (Semen Descurainiae) powder lung moistening blood stasis dispelling again, all medicines share, not only nourishing the lung to keep the adverse QI downward, dissipating blood stasis promote the production of body fluid, and the merit that receipts eliminating pathogenic factor for supporting vital QI consolidates, and have transferred the resistance against diseases of body inherence, the not standby of Modern medical therapy primary disease can be made up, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Flos Farfarae 10 grams, Radix Asteris 10 grams, the Radix Stemonae 8 grams, 8 grams, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 15 grams, Radix Rehmanniae 15 grams, Radix Ophiopogonis 12 grams, Herba Menthae 6 grams, tragacanth 5 grams, Exocarpium Citri Rubrum 6 grams, Radix Polygoni Chinensis 8 grams, Folium Et Cacumen Murrayae 6 grams, Polygonum viviparum L. 8 grams, Crinis Carbonisatus 4 grams, be prepared by following processing step: Flos Farfarae, Radix Asteris, the Radix Stemonae, Rhizoma Phragmitis, Radix Rehmanniae, Radix Ophiopogonis, Herba Menthae, Exocarpium Citri Rubrum, Radix Polygoni Chinensis, Folium Et Cacumen Murrayae, Polygonum viviparum L. are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) tragacanth, Semen Lepidii (Semen Descurainiae) powder, Crinis Carbonisatus are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of wind-warm lung-heat disease of the present invention.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, take 2 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Embodiment 2
Take: Flos Farfarae 9 grams, Radix Asteris 9 grams, the Radix Stemonae 7 grams, 7 grams, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 14 grams, Radix Rehmanniae 14 grams, Radix Ophiopogonis 11 grams, Herba Menthae 5 grams, tragacanth 4 grams, Exocarpium Citri Rubrum 5 grams, Radix Polygoni Chinensis 7 grams, Folium Et Cacumen Murrayae 5 grams, Polygonum viviparum L. 5 grams.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
Take: Flos Farfarae 11 grams, Radix Asteris 11 grams, the Radix Stemonae 9 grams, 9 grams, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 16 grams, Radix Rehmanniae 16 grams, Radix Ophiopogonis 13 grams, Herba Menthae 7 grams, tragacanth 6 grams, Exocarpium Citri Rubrum 7 grams, Radix Polygoni Chinensis 9 grams, Folium Et Cacumen Murrayae 7 grams, Polygonum viviparum L. 9 grams, Crinis Carbonisatus 5 grams.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of wind-warm lung-heat disease, select the routine clinical observation of wind-warm lung-heat patient 48 of diagnosis and treatment since 2010.The wind-warm lung-heat disease diagnostic criteria that patient all meets " Chinese medical disease Standardization of diagnosis and curative effect-2012 editions ", can be diagnosed as wind-warm lung-heat disease.Patient is divided into treatment group and matched group two groups at random, treatment group 24 example, matched group 24 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 7 days, be 1 course for the treatment of, take 2 courses for the treatment of continuously, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
The oral Herba Pileae Scriptae of matched group or winter Ganoderma buccal tablet, 1 time/2h, containing change 1.Neulized inhalation: water for injection 10 ml, gentamycin 40,000 u, vitamin C 1g, dexamethasone 5mg, 1 time/d.Give cefalexin 0.5 g, 3 times/d, oral.Within 7 days, be 1 course for the treatment of, treat 2 courses for the treatment of continuously.
3, efficacy determination:
(1) cure: symptom and sign disappear, laboratory and x-ray etc. inspections recover normal.
(2) take a turn for the better: symptom and sign, lab testing etc. make moderate progress, and x ray examination pulmonary lesions absorbs not yet completely.
(3) do not heal: the state of an illness has no improvement.
4, result:
Select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, cure 22 examples, take a turn for the better 2 examples, and do not heal 0 example, cure rate 91.7%, total effective rate 100%.
Cure 15 examples in matched group, take a turn for the better 6 examples, and do not heal 3 examples, cure rate 62.5%, total effective rate 87.5%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case: Zhang, man, 41 years old.Pathogenic warmth is invaded outward, and by lung and stomach, high fever 8 days, has antiperspirant not understand, thirst and drinking.Red lip constipation, cough with copious phlegm.The sliding number of pulse condition, red tongue with yellow fur.Select the treatment of the embodiment of the present invention 1 Chinese medicinal capsule to cough afterwards for 3 days to subtract, expectorant is thick in vain, and stool is smooth.After continuing to take 5 days, symptom and sign disappear, and laboratory and x-ray etc. inspections recover normal, leave hospital.Follow up a case by regular visits to after 3 months, without recurrence.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.

Claims (6)

1. treat the Chinese medicine preparation of wind-warm lung-heat disease for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Farfarae 9 ~ 11 parts, Radix Asteris 9 ~ 11 parts, the Radix Stemonae 7 ~ 9 parts, 7 ~ 9 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 14 ~ 16 parts, Radix Rehmanniae 14 ~ 16 parts, Radix Ophiopogonis 11 ~ 13 parts, Herba Menthae 5 ~ 7 parts, tragacanth 4 ~ 6 parts, Exocarpium Citri Rubrum 5 ~ 7 parts, Radix Polygoni Chinensis 7 ~ 9 parts, Folium Et Cacumen Murrayae 5 ~ 7 parts, Polygonum viviparum L. 5 ~ 9 parts, Crinis Carbonisatus 0 ~ 5 part.
2. a kind of Chinese medicine preparation for the treatment of wind-warm lung-heat disease according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Farfarae 9 ~ 11 parts, Radix Asteris 9 ~ 11 parts, the Radix Stemonae 7 ~ 9 parts, 7 ~ 9 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 14 ~ 16 parts, Radix Rehmanniae 14 ~ 16 parts, Radix Ophiopogonis 11 ~ 13 parts, Herba Menthae 5 ~ 7 parts, tragacanth 4 ~ 6 parts, Exocarpium Citri Rubrum 5 ~ 7 parts, Radix Polygoni Chinensis 7 ~ 9 parts, Folium Et Cacumen Murrayae 5 ~ 7 parts, Polygonum viviparum L. 5 ~ 9 parts.
3. a kind of Chinese medicine preparation for the treatment of wind-warm lung-heat disease according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Farfarae 9 ~ 11 parts, Radix Asteris 9 ~ 11 parts, the Radix Stemonae 7 ~ 9 parts, 7 ~ 9 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 14 ~ 16 parts, Radix Rehmanniae 14 ~ 16 parts, Radix Ophiopogonis 11 ~ 13 parts, Herba Menthae 5 ~ 7 parts, tragacanth 4 ~ 6 parts, Exocarpium Citri Rubrum 5 ~ 7 parts, Radix Polygoni Chinensis 7 ~ 9 parts, Folium Et Cacumen Murrayae 5 ~ 7 parts, Polygonum viviparum L. 7 ~ 9 parts, Crinis Carbonisatus 3 ~ 5 parts.
4. a kind of Chinese medicine preparation for the treatment of wind-warm lung-heat disease according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Farfarae 10 ~ 11 parts, Radix Asteris 10 ~ 11 parts, the Radix Stemonae 8 ~ 9 parts, 8 ~ 9 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 15 ~ 16 parts, Radix Rehmanniae 15 ~ 16 parts, Radix Ophiopogonis 12 ~ 13 parts, Herba Menthae 6 ~ 7 parts, tragacanth 5 ~ 6 parts, Exocarpium Citri Rubrum 6 ~ 7 parts, Radix Polygoni Chinensis 8 ~ 9 parts, Folium Et Cacumen Murrayae 6 ~ 7 parts, Polygonum viviparum L. 8 ~ 9 parts, Crinis Carbonisatus 4 ~ 5 parts.
5. a kind of Chinese medicine preparation for the treatment of wind-warm lung-heat disease according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Flos Farfarae 10 parts, Radix Asteris 10 parts, the Radix Stemonae 8 parts, 8 parts, Semen Lepidii (Semen Descurainiae) powder, Rhizoma Phragmitis 15 parts, Radix Rehmanniae 15 parts, Radix Ophiopogonis 12 parts, Herba Menthae 6 parts, tragacanth 5 parts, Exocarpium Citri Rubrum 6 parts, Radix Polygoni Chinensis 8 parts, Folium Et Cacumen Murrayae 6 parts, Polygonum viviparum L. 8 parts, Crinis Carbonisatus 4 parts.
6. treat the preparation method of the Chinese medicine preparation of wind-warm lung-heat disease for one kind, it is characterized in that, comprise the steps: that Flos Farfarae, Radix Asteris, the Radix Stemonae, Rhizoma Phragmitis, Radix Rehmanniae, Radix Ophiopogonis, Herba Menthae, Exocarpium Citri Rubrum, Radix Polygoni Chinensis, Folium Et Cacumen Murrayae, Polygonum viviparum L. are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use;
(2) tragacanth, Semen Lepidii (Semen Descurainiae) powder, Crinis Carbonisatus are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use;
(3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of wind-warm lung-heat disease of the present invention.
CN201410691377.6A 2014-11-27 2014-11-27 Traditional Chinese medicine preparation for treating wind-warm lung-heat disease Pending CN104435939A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961584A (en) * 2014-05-29 2014-08-06 刘士和 Medicine for treating lung heat and preparation method thereof
CN104127738A (en) * 2014-08-18 2014-11-05 青岛百慧智业生物科技有限公司 Traditional Chinese medicine for treating bronchiectasia caused by phlegm-heat obstructing lung and a preparation method thereof

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961584A (en) * 2014-05-29 2014-08-06 刘士和 Medicine for treating lung heat and preparation method thereof
CN104127738A (en) * 2014-08-18 2014-11-05 青岛百慧智业生物科技有限公司 Traditional Chinese medicine for treating bronchiectasia caused by phlegm-heat obstructing lung and a preparation method thereof

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