CN104435915A - Traditional Chinese medicine mixture for treating psoriasis - Google Patents
Traditional Chinese medicine mixture for treating psoriasis Download PDFInfo
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- CN104435915A CN104435915A CN201410664120.1A CN201410664120A CN104435915A CN 104435915 A CN104435915 A CN 104435915A CN 201410664120 A CN201410664120 A CN 201410664120A CN 104435915 A CN104435915 A CN 104435915A
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2068—Compounds of unknown constitution, e.g. material from plants or animals
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Abstract
The invention discloses a traditional Chinese medicine mixture for treating psoriasis. The mixture is characterized by being prepared from the following traditional Chinese medicinal raw materials in parts by weight: 20-40 parts of rhizoma smilacis glabrae, 10-20 parts of honeysuckle, 5-15 parts of radix sophorae tonkinensis, 10-20 parts of radix isatidis, 10-20 parts of paris polyphylla sm, 10-20 parts of cortex dictamni, 5-10 parts of radix clematidis and 5-10 parts of licorice root. The mixture is prepared by a formula containing traditional Chinese medicinal materials with effects of clearing heat, removing toxicity, dispelling dampness, removing pyralysis, promoting blood circulation to remove stasis and the like, has the advantages of remarkable curative effect, strong sterilization capability, quick response, no toxic or side effect, symptom and root cause treatment, no relapse after curing and the like when used for treating psoriasis.
Description
Technical field:
The present invention relates to technical field of Chinese medicine, is exactly specifically that one treats psoriasic Traditional Chinese drug mixture.
Background technology:
Psoriasis is a kind of common chronic inflammatory dermatoses being easy to recur with characteristic skin lesion.From the beginning of being inflammatory red papules, about foxtail millet grain is to Semen phaseoli radiati size, and expanding gradually later or merging becomes brownish red speckle, clear border, and have inflammatory blush around, substrate infiltrates obviously, the canescence of surface coverage multilamellar drying or silvery white squama.Scraper surface squama gently, exposes the semitransparent thin film that one deck pale red is shinny gradually, claims film phenomenon.Strike off thin film again, then occur little petechia, claim petechial hemorrhage phenomenon.White squama, shinny thin film and petechial hemorrhage are the psoriatic key characters of diagnosis, are called that three levy.Psoriasis easily recurs, and winter in spring easily recurs or increases the weight of, and many alleviations summer and autumn.Medical science current research finds: the obstinate refractory of psoriasis and the basic reason of easily recurrence are long-term " accumulation " of " tinea toxin " in blood samples of patients and are on the increase, a large amount of tinea toxin flows through whole body by blood, pour into skin, invade skin and form the psoriasis of furuncle, erythema, desquamation.Treat the hormones of dermatosis in the market, chemical classes, Chinese medicine class medicament categories are various, the shortcomings such as though prescription is different, curative effect is poor, and side effect is many.
Summary of the invention:
The present invention, exactly for overcoming deficiency of the prior art, providing a kind of and has instant effect for psoriasis treatment, short treating period, cure rate are high, and taking stopgap measures and effect a permanent cure, the Chinese medicinal formulae no longer recurred more.
The invention provides following technical scheme:
One treats psoriasic Traditional Chinese drug mixture, it is characterized in that being made up of following weight proportion raw material of Chinese medicine: Rhizoma Smilacis Glabrae 20-40 part, Caulis Lonicerae 10-20 part, Radix Sophorae Tonkinensis 5-15 part, Radix Isatidis 10-20 part, Rhizoma Paridis 10-20 part, Cortex Dictamni 10-20 part, Radix Clematidis 5-10 part, Radix Glycyrrhizae 5-10 part.
Optimization formula is:
Rhizoma Smilacis Glabrae 30 parts, Caulis Lonicerae 15 parts, Radix Sophorae Tonkinensis l0 part, Radix Isatidis 15 parts, Rhizoma Paridis 15 parts, Cortex Dictamni 15 parts, Radix Clematidis 6 parts, 6 parts, Radix Glycyrrhizae.
Preparation and instructions of taking:
Get above-mentioned each raw material of Chinese medicine by weight ratio, after screening-elutriation-oven dry, be ground into 600 fine powders by after all raw material mixing, then make honeyed pill, every ball net weight 6 grams.
Take medicine every day 3 times, each two balls.Serveing on 15 is a course for the treatment of.
Form being described in detail as follows of each raw material of Chinese medicine of the present invention:
Rhizoma Smilacis Glabrae: sweet in the mouth, light, property is put down.Return liver, stomach warp.There is dehumidifying, removing toxic substances, the effects such as easing joint movement.Be usually used in damp and hot stranguria with turbid discharge, leukorrhagia, carbuncle, scrofula, scabies, syphilis and the limbs contracture caused by mercurialism, the diseases such as bones and muscles pain.This product also has antitumor, removing toxic substances, the effects such as promoting blood circulation, cholesterol reducing, removing toxic substances and promoting subsidence of swelling, treatment of arthritis and promoting collateral and channels of relaxing.
Caulis Lonicerae: sweet in the mouth, cold in nature.Attach to the lung and stomach meridians.There is heat-clearing and toxic substances removing, the effects such as dispelling wind dredging collateral.Be usually used in epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, beriberoid pyretic arthralgia, the diseases such as redness and swelling of joints burning pain.Luteolin contained in this product can suppress the growth of staphylococcus and bacillus subtilis, to mucositis, Candida albicans, typhoid fever, dysentery, to Bacillus typhi, shigella flexneri, staphylococcus aureus and bacillus pyocyaneus, Bacillus typhi, shigella flexneri and staphylococcus aureus tool inhibitory action, also there is stronger anti-infectious function in vivo.This product strengthens blood capillary in addition, reduces the effect of blood cholesterol.
Radix Sophorae Tonkinensis: bitter in the mouth, cold in nature; Poisonous.Attach to the lung and stomach meridians.There is heat-clearing and toxic substances removing, the effects such as detumescence sore-throat relieving.Be usually used in fire-toxin to pent up, laryngopharynx swelling and pain, the diseases such as gingivitis.Experiment shows: the extract of Radix Sophorae Tonkinensis, matrine and oxymatrine, to the mice of mice transplanted sarcoma, have the effect delaying its death.To solid type and the ascitic type Jitian meat cancer of rat and the rat of Example Ascites hepatoma is had to the effect significantly delaying its death, the rat of average 60% does not have death and can cure, and finds that there is the existence of antitumor activity antibody in the rat blood serum of curing; Radix Sophorae Tonkinensis methylene blue test tube method has inhibitory action to leukaemia; Have excitation to reticuloendothelial system function, under the microscope, the phagocyte of engulfing carbon is higher than matched group; Antiulcer action; Have and suppress gastric secretion effect, for the rat of Experimental oral ulcer (pylorus ligation ulcer, stress ulcer, acetic acid ulcer), oral administration has obvious repair to chronic ulcer tissue; This product all has inhibitory action to staphylococcus aureus, acrothesium floccosum and Candida albicans.
Radix Isatidis: bitter in the mouth, cold in nature.GUIXIN, stomach warp.There is heat-clearing and toxic substances removing, the effects such as removing heat from blood sore-throat relieving.Be usually used in maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, the diseases such as carbuncle.Infusion has inhibitory action to bacillus subtilis, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, paratyphoid fever bacillus, dysentery bacterium, bacillus enteritidis etc.; Acetone leachate also has similar effect, and effective to Hemolytic streptococcus.In addition, kill leptospira in addition, reduce the effects such as capillary permeability, anticoagulant, removing toxic substances, resisting gram-positive and negative bacteria.
Rhizoma Paridis: bitter in the mouth, cool in nature.Mild toxicity.GUIXIN warp, Liver Channel, lung meridian, stomach warp, large intestine channel.There is the effects such as anticancer, the reducing swelling and alleviating pain of relieving internal heat, heat clearing away arresting convulsion, antitussive and antiasthmatic.Be commonly used to the diseases such as treatment carbuncle pulmonary tuberculosis chronic cough, traumatic injury, snake bite and insect sting, lymphoid tuberculosis, osteomyelitis.The water logging agent of this product and decoct all have inhibitory action to Bacillus typhi, paratyphoid bacillus A, will he and shigella flexneri in vitro; Analgesia; Calm; Relieving asthma, cough-relieving; All antibacterial action is had to the various pathogens such as Bacterium entericum and pyococcus.
Cortex Dictamni: bitter in the mouth; Salty; Cold in nature.Return spleen; Lung; Small intestinal;
stomach; Urinary bladder channel.There is heat clearing and damp drying; Dispelling wind for relieving itching; The effects such as removing toxic substances.Be usually used in the rubella caused by wind heat noxious dampness; Eczema; Scabies; Jaundice; The diseases such as damp-heat arthralgia.This product tests 1 in vitro
:the infusion of 4 to multiple pathomycete as trichophyton, Trichophyton concentricunm, oidium schoenleinii, all there is inhibitory action in various degree, but have the ether of report this product, ethanol and water extract to be showed no effect to the coccuses such as golden yellow, escherichia coli bacillus pyocyaneus and Mycobacterium phlei.Dictaminine contained by this product has excitation to isolated frog heart when a small amount of, and cardiac muscular tension can be made to increase, and minute output and rich output all increase.Obvious contraction is had in vitro rabbit ear blood vessel.Contained fagarine has antiarrhythmic effect, and bacterium taro alkali has the effect of ephedrine sample, and anesthetized cat blood pressure can be made to increase, and strengthens the contraction of cat instant embrane, coronary artery dilating, strengthens adrenergic boosting.
Radix Clematidis: acrid in the mouth, salty, warm in nature.Return urinary bladder channel.There is expelling wind and removing dampness, the effects such as removing obstruction in the collateral to relieve pain.Be usually used in rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone is choked with sobs the diseases such as larynx.Radix Clematidis preserved material has the effect significantly strengthening glucose assimilation to normal rat, therefore may have hypoglycemic activity.Have Isolated Toad Heart and first suppress rear excited effect, larger than decoct 3 ~ 5 times of the drug effect of preserved material.The preserved material (1ml/kg) of 50% can make the blood pressure drops of anesthetized dog, kidney smaller volume, the drug effect of preserved material be 2 times of decoct, and its hypotensive effect is like relevant with to the suppression of heart.This product in vitro, water logging agent has inhibitory action to dermatophytes, water logging agent also has inhibitory action to microsporon audouini, decoct has inhibitory action to staphylococcus aureus, shigella, decoct lumbar injection can slightly improve the mice threshold of pain, point out it to have analgesic activity, decoct has inhibitory action to plasmodium, and alcohol extract is to mice
[2]midtrimester of pregnancy has the effects such as induced labor.
Radix Glycyrrhizae: sweet in the mouth, property is put down.Return stomach, lung, spleen channel.There is invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, the effects such as coordinating the actions of various ingredients in a prescription.Be usually used in weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, the disease such as strong.This product has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic, anticancer, conditioner body immunity function, arrhythmia, blood fat reducing, anti-
atherosclerosis, anticoagulant, the pharmacological action such as antitumor.
Advantage of the present invention:
Formula of the present invention utilizes the Chinese medicines such as heat-clearing and toxic substances removing, damp eliminating eliminating impediment, blood circulation promoting and blood stasis dispelling, has that curative effect shows, sterilizing power is strong, instant effect, to have no side effect, and take stopgap measures and effect a permanent cure for curing psoriasis, the no longer advantage such as recurrence more.
Detailed description of the invention:
Embodiment 1:
One treats psoriasic Traditional Chinese drug mixture, it is characterized in that being made up of following weight proportion raw material of Chinese medicine: Rhizoma Smilacis Glabrae 30 parts, Caulis Lonicerae 15 parts, Radix Sophorae Tonkinensis l0 part, Radix Isatidis 15 parts, Rhizoma Paridis 15 parts, Cortex Dictamni 15 parts, Radix Clematidis 6 parts, 6 parts, Radix Glycyrrhizae.
Embodiment 2:
One treats psoriasic Traditional Chinese drug mixture, it is characterized in that being made up of following weight proportion raw material of Chinese medicine: Rhizoma Smilacis Glabrae 20 parts, Caulis Lonicerae 10 parts, Radix Sophorae Tonkinensis 8 parts, Radix Isatidis 12 parts, Rhizoma Paridis 13 parts, Cortex Dictamni 12 parts, Radix Clematidis 5 parts, 5 parts, Radix Glycyrrhizae.
Embodiment 3:
One treats psoriasic Traditional Chinese drug mixture, it is characterized in that being made up of following weight proportion raw material of Chinese medicine: Rhizoma Smilacis Glabrae 40 parts, Caulis Lonicerae 20 parts, Radix Sophorae Tonkinensis 15 parts, Radix Isatidis 20 parts, Rhizoma Paridis 20 parts, Cortex Dictamni 20 parts, Radix Clematidis 10 parts, 10 parts, Radix Glycyrrhizae.
Embodiment 1-3 all adopts following preparation and instructions of taking:
Get above-mentioned each raw material of Chinese medicine by weight ratio, after screening-elutriation-oven dry, be ground into 600 fine powders by after all raw material mixing, then make honeyed pill, every ball net weight 6 grams.
Take medicine every day 3 times, each two balls.Serveing on 15 is a course for the treatment of.The period in a medicine not seafood such as the pungent irritable food of edible and fish and shrimp, river is fresh, and beef and mutton etc.
Model case:
1, patient's journey, man 24 years old.Cervical region suffered from psoriasis more than 1 year, and originally erythema is less, and pruritus is not obvious; Erythema became many gradually afterwards, and substrate infiltrates obviously, and skin lesion surface is covered with multilamellar silvery white squama, and easily strike off, pruritus is hard to bear.After taking a course for the treatment of of the present invention, pruritus obviously alleviates; 4 courses for the treatment of of continual cure, cure.Follow up a case by regular visits to without recurrence.
2, grandson patient so-and-so, female 45 years old, starts head from calendar year 2001 and occurs red papules, see white scales after scratching.2005 there is erythra in two upper limb, axillary fossas, are diagnosed as psoriasis at local hospital, treat many months invalid in March, 2008 here go to a doctor; Look into: large stretch of erythra all appears in back, buttocks, chest, above cover thick squama, wipe the visible thin film of squama and petechia off.Take effect after taking a course for the treatment of of the present invention, continual cure was fully recovered after 4 courses for the treatment of.
3, patient Liu so-and-so, female 51 years old, 2003 start to suffer from psoriasis, and illing skin is filbert lamellar, coarse plumpness, and run into strong wind and then itch, night itches more so.Period once treated by multiple method, made moderate progress, but can recur again later.After taking a course for the treatment of of the present invention, symptom obviously alleviates, and continues again to take 2 courses for the treatment of, and recovery from illness, did not recur so far.
Claims (2)
1. treat a psoriasic Traditional Chinese drug mixture, it is characterized in that being made up of following weight proportion raw material of Chinese medicine: Rhizoma Smilacis Glabrae 20-40 part, Caulis Lonicerae 10-20 part, Radix Sophorae Tonkinensis 5-15 part, Radix Isatidis 10-20 part, Rhizoma Paridis 10-20 part, Cortex Dictamni 10-20 part, Radix Clematidis 5-10 part, Radix Glycyrrhizae 5-10 part.
2. treat psoriasic Traditional Chinese drug mixture according to the one described in claim 1, it is characterized in that being made up of following weight proportion raw material of Chinese medicine: Rhizoma Smilacis Glabrae 30 parts, Caulis Lonicerae 15 parts, Radix Sophorae Tonkinensis l0 part, Radix Isatidis 15 parts, Rhizoma Paridis 15 parts, Cortex Dictamni 15 parts, Radix Clematidis 6 parts, 6 parts, Radix Glycyrrhizae.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410664120.1A CN104435915A (en) | 2014-11-20 | 2014-11-20 | Traditional Chinese medicine mixture for treating psoriasis |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410664120.1A CN104435915A (en) | 2014-11-20 | 2014-11-20 | Traditional Chinese medicine mixture for treating psoriasis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194467A (en) * | 2015-11-08 | 2015-12-30 | 长沙佰顺生物科技有限公司 | Traditional Chinese medicine composition for treating psoriasis |
| CN105521470A (en) * | 2015-11-30 | 2016-04-27 | 吕翠云 | Traditional Chinese medicinal composition for treating pustular psoriasis |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000191543A (en) * | 1998-12-28 | 2000-07-11 | Lion Corp | Skin preparation for external use |
| CN103417792A (en) * | 2013-07-30 | 2013-12-04 | 张英琴 | Traditional Chinese medicine for treating eczema |
-
2014
- 2014-11-20 CN CN201410664120.1A patent/CN104435915A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000191543A (en) * | 1998-12-28 | 2000-07-11 | Lion Corp | Skin preparation for external use |
| CN103417792A (en) * | 2013-07-30 | 2013-12-04 | 张英琴 | Traditional Chinese medicine for treating eczema |
Non-Patent Citations (2)
| Title |
|---|
| 李伟凡 等: "凉血活血汤治疗寻常型银屑病临床观察", 《临床皮肤科杂志》 * |
| 王旭东: "《中医外科处方手册》", 30 November 2005, 科学技术文献出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105194467A (en) * | 2015-11-08 | 2015-12-30 | 长沙佰顺生物科技有限公司 | Traditional Chinese medicine composition for treating psoriasis |
| CN105521470A (en) * | 2015-11-30 | 2016-04-27 | 吕翠云 | Traditional Chinese medicinal composition for treating pustular psoriasis |
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