CN104435764A - Traditional Chinese medicine composition for treating diabetes and preparation process thereof - Google Patents
Traditional Chinese medicine composition for treating diabetes and preparation process thereof Download PDFInfo
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Abstract
The invention relates to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating diabetes and a preparation process thereof. The traditional Chinese medicine composition is characterized by being prepared from the following raw medicines in parts by weight: 300-500 parts of gypsum, 9-15 parts of rhizoma anemarrhenae, 9-15 parts of radix ophiopogonis, 9-15 parts of radix achyranthis bidentatae, 9-15 parts of dendrobe, 6-10 parts of radix rehmanniae recen, 6-10 parts of radix trichosanthis, 3-5 parts of coptis chinensis and 3-5 parts of fructus gardenia. The traditional Chinese medicine composition disclosed by the invention follows the treatment rules of clearing stomach, cooling blood, nourishing yin and generating body fluid, has the effects of generating body fluid, nourishing yin, tonifying qi, clearing heat of stomach and heart, purging fire for removing toxin, cooling blood, relieving restlessness and the like by combination of various medicines, has a good treatment effect on various types of diabetes and complications of the diabetes, and is free of toxic and side effects.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine composition and the preparation technology thereof that treat diabetes.
Background technology
Diabetes are a kind of chronic lifelong participation diseases, act on that body causes hypoinsulinism, insulin resistant etc. and the internal metabolism that causes is lacked of proper care and hyperglycemia state by the various virulence factor such as inherited genetic factors, immunologic function disorder.In national diabetes survey of carrying out in 1980, diabetes prevalence is 6.09%.According to World Health Organization's prediction, China in 2025 has made a definite diagnosis diabetes total number of persons and will reach 5,000 ten thousand people, is nineteen ninety-five 1.68 times of ill total number of persons, and rate of increase occupies first place, the whole world, and the severe situation of diabetes makes people more and more pay attention to the preventing and controlling of diabetes.
At present, the treatment of diabetes mainly relies on the medicines such as insulin injection, oral biguanides, sulphanylureas and alpha-glucosidase inhibitor and reaches symptoms such as improving patient's " three-many-one-little ", thus control blood glucose, glucose in urine increase and temporary transient symptom management, but still existence damages liver, kidney stomach function regulating, causes the side effect such as hypoglycemia, edema, also cannot avoid the appearance of complication simultaneously.
The traditional Chinese medical science thinks that diabetes spp is in diabetes category, and pathogenesis is YIN fluid deficiency, scorching inclined Sheng, the rule for the treatment of many employings nourishing YIN and clearing away heat, blood circulation promoting and blood stasis dispelling, Yishen Jianpi etc.Chinese medicine has the characteristic of organic conception and determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, and while treatment primary symptom, take into account complication, effective component group more plays Mutiple Targets, multipath pharmacology.Therefore, the effect of compound of Chinese medicine diabetes and complication thereof is subject to people's attention day by day.
Summary of the invention
The object of the invention is the weak point overcoming original treatment means, provide a kind of safe and reliable, have no side effect, taking convenience, stable curative effect, the medicine of the treatment diabetes not easily developed complications.
The object of the present invention is achieved like this:
Treat a Chinese medicine composition for diabetes, raw material is by weight Gypsum Fibrosum 300-500 part, Rhizoma Anemarrhenae 9-15 part, Radix Ophiopogonis 9-15 part, Radix Achyranthis Bidentatae 9-15 part, Herba Dendrobii 9-15 part, Radix Rehmanniae 6-10, Radix Trichosanthis 6-10 part, Rhizoma Coptidis 3-5 part, Fructus Gardeniae 3-5 part.
Above-mentioned Radix Achyranthis Bidentatae is Radix Cyathulae.
The preparation method of the Chinese medicine composition for the treatment of diabetes is as follows:
(1) Gypsum Fibrosum is decocted first, and decocts Tang Daishui, and filtrate soaks following taste medicine;
(2) Herba Dendrobii is pulverized for subsequent use;
(3) Rhizoma Anemarrhenae, Radix Ophiopogonis, Radix Achyranthis Bidentatae, the Radix Rehmanniae, Radix Trichosanthis, Rhizoma Coptidis, Fructus Gardeniae mixes by weight, in mixture, add 3 times of Gypsum Fibrosum decoct soup and carry out decoction 1.5 hours, filter, then in filtering residue, add 2 times of Gypsum Fibrosum decoct soup and carry out decoction 1 hour, filter, merging filtrate, then concentrate filtrate to thick shape, cool for subsequent use;
(4) filtrate thick paste and Dendrobium are mixed, pulverize after cold drying, incapsulate in shell, obtained hard capsule.
Described preparation method, is characterized in that:
Step (1) Gypsum Fibrosum should be decocted first, and leaches for subsequent use during 10 times of decoctings to 5 times;
Step (2) Herba Dendrobii crosses 60 mesh sieves after pulverizing, for subsequent use;
After step (3) concentrating under reduced pressure, the relative density of thick paste is 1.14-1.20;
The temperature of step (4) drying under reduced pressure is 60 DEG C, time 1.5h; 60 mesh sieves are crossed after pulverizing.
The pharmaceutical characteristic of each medical material that the present invention adopts is:
Gypsum Fibrosum: clearing away heat-fire, relieving restlessness is quenched the thirst.Cure mainly epidemic febrile disease edema caused by disorder of QI excess-heat syndrome, dyspnea and cough due to lung-heat card, toothache due to stomach-fire, headache, excess-heat are quenched one's thirst, ulcer being unable to heal, eczema pruritus.
The Rhizoma Anemarrhenae: clearing away heat-fire is nourshing Yin and drynsessmoistening prescription.Cure mainly epidemic febrile disease high hot excessive thirst, cough due to lung-heat, osteopyrexia and fever, seminal emission, night sweat, restlessness of asrhenia type and insomnia, quench one's thirst.
Radix Ophiopogonis: nourishing YIN and moistening the lung, reinforcing stomach reg fluid, clear away heart-fire relieving restlessness.Cure mainly dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound thirsty, quench one's thirst, vexed insomnia, have sore throat, dryness of the intestine constipation.
Radix Achyranthis Bidentatae: promoting blood circulation to restore menstrual flow, invigorating the liver and kidney, bone and muscle strengthening, relieving stranguria by diuresis, ignite (blood) are descending.Cure mainly stagnation of blood stasis amenorrhea, traumatic injury, soreness of waist and knee joint, stranguria, headache, dizzy, haematemesis.
Herba Dendrobii: reinforcing stomach reg fluid, nourishing YIN and clearing away heat.Cure mainly consumption of body fluid caused by febrile disease, excessive thirst, poor vision, hyperactivity of fire caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever.
The Radix Rehmanniae: clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting.Cure mainly that heat enters nutrient blood, crimson tongue excessive thirst, yin asthenia generating intrinsic heat, Tianjin wound is thirsty, interior-heat is quenched one's thirst, hectic fever due to YIN-deficiency consumptive fever.
Radix Trichosanthis: clearing away heat and promoting production of body fluid, moistening the lung and resolving phlegm, detumescence and apocenosis.Cure mainly that calentura is thirsty, polydipsia of quenching one's thirst, lung-heat type cough, sore swollen toxin.
Rhizoma Coptidis: heat clearing and damp drying, eliminating fire and detoxication.Cure mainly damp and hot feeling of fullness, vomiting acid regurgitation, damp-heat dysentery, dysphoria and insomnia, carbuncle scabies, external treatment eczema of quenching one's thirst, auditory meatus suppurate.
Fructus Gardeniae: pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Cure mainly that calentura is vexed, jaundice due to damp-heat, blood strangury and dry pain, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles.
In the present invention, Gypsum Fibrosum is apt to clearing away stomach-heat, nourishing kidney-yin of holding concurrently; The clear and rich product such as the Rhizoma Anemarrhenae, Radix Ophiopogonis, Herba Dendrobii are apt to YIN nourishing and the production of body fluid promoting; The impairment of YIN that the Radix Rehmanniae is apt to clearing away stomach-heat hyperamization heat damages liquid; Radix Cyathulae heat conduction conducting blood to flow downwards, and blood circulation promoting and blood stasis dispelling; Rhizoma Coptidis bitter cold, one helps Gypsum Fibrosum clearing stomach fire, and two help the Radix Rehmanniae to support kidney yin, except heart stomach-fire; The kind fire rushing down three Jiao of Fructus Gardeniae.All medicines coordinate, and play clearing stomach and cooling blood, effect of YIN nourishing and the production of body fluid promoting.
The present invention is with clearing stomach and cooling blood, YIN nourishing and the production of body fluid promoting for the rule for the treatment of, and the effects such as various compatibility of drugs combination performance is promoted the production of body fluid, yin nourishing, QI invigorating, the stomach-fire that clears away heart-fire, eliminating fire and detoxication, removing heat from blood relieving restlessness, the diabetes for multiple disease type have good therapeutic effect.
Clinical observation:
(1) clinical data
The present inventor in 2012 so far, carries out clinical observation treatment to 96 routine diabeticss.
(2) Therapeutic Method
Warm water takes orally, three times on the one, each 2 ~ 3, one after each meal.Calculate treatment time according to conditions of patients weight, patients with mild takes about 3 months, and severe case serve on 5 months and can fully recover.
(3) curative effect determinate standard
Cure: symptom all disappears; Main Physico-chemical tests index is normally.
Alleviate: whole or cardinal symptom disappears substantially; Main Physico-chemical tests index makes moderate progress.
Invalid: main Physico-chemical tests index is front unchanged with treatment.
(4) clinical effectiveness
Clinical cure 67 example (69.8%), alleviates 19 examples (19.8%), and invalid 9 examples (9.4%), total effective rate is 90.6%.
Compatibility science of the present invention, preparation is simple, and stable curative effect is reliable, and have no side effect, safety is high, is conducive to sufferer and alleviates condition of illness in time.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described:
Embodiment 1
Gypsum Fibrosum 300g is decocted first, and decocts Tang Daishui, leaches filtrate for subsequent use during 10 times of decoctings to 5 times; 60 mesh sieves are crossed after Herba Dendrobii 2g pulverizes, for subsequent use; By Rhizoma Anemarrhenae 9g, Radix Ophiopogonis 9g, Radix Achyranthis Bidentatae 9g, Radix Rehmanniae 6g, Radix Trichosanthis 6g, Rhizoma Coptidis 3g, Fructus Gardeniae 3g mixes by weight, adds 3 times of Gypsum Fibrosum and decoct soup and carry out decoction 1.5 hours in mixture, filters, in filtering residue, add 2 times of Gypsum Fibrosum again decoct soup and carry out decoction 1 hour, filter, merging filtrate, then concentrate filtrate to thick shape, relative density is 1.14, cools for subsequent use; Above-mentioned filtrate thick paste and Dendrobium are mixed, pulverizes after 60 DEG C of dry 1.5h, incapsulate in shell, obtained hard capsule.
Embodiment 2
Gypsum Fibrosum 500g is decocted first, and decocts Tang Daishui, leaches filtrate for subsequent use during 10 times of decoctings to 5 times; 60 mesh sieves are crossed after Herba Dendrobii 3g pulverizes, for subsequent use; By Rhizoma Anemarrhenae 15g, Radix Ophiopogonis 15g, Radix Achyranthis Bidentatae 15g, Radix Rehmanniae 10g, Radix Trichosanthis 10g, Rhizoma Coptidis 5g, Fructus Gardeniae 5g mixes by weight, adds 3 times of Gypsum Fibrosum and decoct soup and carry out decoction 1.5 hours in mixture, filters, in filtering residue, add 2 times of Gypsum Fibrosum again decoct soup and carry out decoction 1 hour, filter, merging filtrate, then concentrate filtrate to thick shape, relative density is 1.20, cools for subsequent use; Above-mentioned filtrate thick paste and Dendrobium are mixed, pulverizes after 60 DEG C of dry 1.5h, incapsulate in shell, obtained hard capsule.
Claims (4)
1. treat a Chinese medicine composition for diabetes, it is characterized in that: be made up of the raw material of following parts by weight, Gypsum Fibrosum 300-500 part, Rhizoma Anemarrhenae 9-15 part, Radix Ophiopogonis 9-15 part, Radix Achyranthis Bidentatae 9-15 part, Radix Rehmanniae 6-10, Radix Trichosanthis 6-10 part, Rhizoma Coptidis 3-5 part, Fructus Gardeniae 3-5 part, Herba Dendrobii 2-3 part.
2. the Chinese medicine composition for the treatment of diabetes according to claim 1, is characterized in that above-mentioned Radix Achyranthis Bidentatae is Radix Cyathulae.
3. the preparation method for the treatment of the Chinese medicine composition of diabetes is as follows:
(1) Gypsum Fibrosum is decocted first, and decocts Tang Daishui, and filtrate soaks following taste medicine;
(2) Herba Dendrobii is pulverized for subsequent use;
(3) Rhizoma Anemarrhenae, Radix Ophiopogonis, Radix Achyranthis Bidentatae, the Radix Rehmanniae, Radix Trichosanthis, Rhizoma Coptidis, Fructus Gardeniae mixes by weight, in mixture, add 3 times of Gypsum Fibrosum decoct soup and carry out decoction 1.5 hours, filter, then in filtering residue, add 2 times of Gypsum Fibrosum decoct soup and carry out decoction 1 hour, filter, merging filtrate, then concentrate filtrate to thick shape, cool for subsequent use;
(4) filtrate thick paste and Dendrobium are mixed, pulverize after cold drying, incapsulate in shell, obtained hard capsule.
4. preparation method according to claim 3, is characterized in that:
Step (1) Gypsum Fibrosum should be decocted first, and leaches for subsequent use during 10 times of decoctings to 5 times;
Step (2) Herba Dendrobii crosses 60 mesh sieves after pulverizing, for subsequent use;
After step (3) concentrating under reduced pressure, the relative density of thick paste is 1.14-1.20;
The temperature of step (4) drying under reduced pressure is 60 DEG C, time 1.5h; 60 mesh sieves are crossed after pulverizing.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031225A (en) * | 2015-09-10 | 2015-11-11 | 任德旺 | Traditional Chinese medicine preparation for treating diabetes |
| CN113304224A (en) * | 2021-04-28 | 2021-08-27 | 中国热带农业科学院热带作物品种资源研究所 | Medicinal and edible tropical water lily composition formula for assisting in regulating blood sugar and preparation method thereof |
| CN114588228A (en) * | 2021-06-24 | 2022-06-07 | 北京精医和生梅奥中医诊所有限公司 | Composition for treating type 2 diabetes |
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- 2014-12-12 CN CN201410758952.XA patent/CN104435764A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105031225A (en) * | 2015-09-10 | 2015-11-11 | 任德旺 | Traditional Chinese medicine preparation for treating diabetes |
| CN113304224A (en) * | 2021-04-28 | 2021-08-27 | 中国热带农业科学院热带作物品种资源研究所 | Medicinal and edible tropical water lily composition formula for assisting in regulating blood sugar and preparation method thereof |
| CN114588228A (en) * | 2021-06-24 | 2022-06-07 | 北京精医和生梅奥中医诊所有限公司 | Composition for treating type 2 diabetes |
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Application publication date: 20150325 |