CN104435645A - Traditional Chinese medicinal composition applied after breast cancer operation and preparation method of traditional Chinese medicinal composition - Google Patents
Traditional Chinese medicinal composition applied after breast cancer operation and preparation method of traditional Chinese medicinal composition Download PDFInfo
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- CN104435645A CN104435645A CN201410779935.4A CN201410779935A CN104435645A CN 104435645 A CN104435645 A CN 104435645A CN 201410779935 A CN201410779935 A CN 201410779935A CN 104435645 A CN104435645 A CN 104435645A
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Abstract
The invention discloses a traditional Chinese medicinal composition applied after breast cancer operation. The traditional Chinese medicinal composition consists of fingered citron, fructus citri, spina gleditsiae, honeysuckle, tangerine pith, ligusticum wallichii, cassia bark, wild aconite, radix aconite, earthworm, stiff silkworm, radix bupleuri, szechwan Chinaberry fruit, rhizoma corydalis, scutellaria barbata, oldenlandia diffusa, asarum, trogopterus dung, thunberg fritillary bulb, kelp, seaweed and costus root according to certain proportions by weight. The traditional Chinese medicinal composition has functions of soothing liver and regulating qi, relieving swelling and expelling pus, promoting circulation of blood and qi, eliminating blood stasis and stopping blooding, and can be used for effectively treating postoperative breast cancer complications.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, be specifically related to a kind of Chinese medicine composition for Mammary cancer.The invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
Breast carcinoma is one of modal malignant tumor of women, and according to statistics, sickness rate accounts for the 7-10% of the various malignant tumor of whole body.Its morbidity is normal relevant with heredity, and women's sickness rate between 40-60 years old, before and after menopause is higher.Usually occur in the malignant tumor of breast glandular epithelium tissue.That one has a strong impact on one of even life-threatening modal malignant tumor of women's physical and mental health.The Therapeutic Method of breast carcinoma has operation, chemotherapy, radiotherapy, endocrine therapy, Biotherapeutics, Chinese medicine etc.Operation is at present first-selected Therapeutic Method, but breast cancer operation can excise lymph, make a series of complication of car, mainly contain hemorrhage, hydrops, flap necrosis, edema of the upper extremity, breast carcinoma arm edema etc., and after corrective surgery, lose the second healthy femaleness and produce anxiety, insomnia, severe depression etc., after mammary cancer radical operation, because lymphsystem is damaged, the smooth or cephalic vein of lymphatic return from arm is by ligation, cause protein to build up in tissue, osmotic pressure is raised, absorb moisture and cause suffering limb lymphedema.
The traditional Chinese medical science thinks that mainly golden sword kills blood trouble vitality of pulse warp in art, and meridian stasis is stagnant, caused by QI-blood circulation is smooth.It is common complication obstinate again.Severe patient can cause abnormal appearance, weak, repeated infection and upper limb disorder, adds misery and the depression of patient, has a strong impact on the quality of life of patient.But it seems at present, in the relatively advanced city of medical condition, people are hospital treatments, general is all use Western medicine or have an injection to treat, and in small towns, or more remote village, the corrective surgery suffering from breast carcinoma has been make family debt-ridden, because family income is low, economic condition is poor, locality lacks medical condition, need to take the time if want to cure the disease, go to seek medical advice in the city going medical condition more flourishing with a large amount of travelling expenses, in addition the medical expense of the costliness of hospital, people often do not go sick, give free rein to recovery from illness, therefore some patient often delays the opportunity for the treatment of.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition, this Chinese medicine composition has determined curative effect for treatment Operative complications of breast carcinoma, and cheap, healing time is short, the simple feature of method.
Another object of the present invention is to provide the preparation method of the Chinese medicine preparation of this treatment Operative complications of breast carcinoma.
Inventor is in clinical treatment practice for many years, observe the misery that Operative complications of breast carcinoma brings to patient, according to the law of development of this disease, and the combination principle of Chinese medicine, and by a large amount of clinical verifications, Exploration and conclusion goes out a kind of new formula of the Chinese medicine preparation for Mammary cancer repeatedly, the present invention selects Fructus Citri Sarcodactylis, Fructus Citri, Spina Gleditsiae, Flos Lonicerae, Vascular aurantii, Rhizoma Chuanxiong, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Radix Aconiti, Pheretima, Bombyx Batryticatus, Radix Bupleuri, Fructus Toosendan, Rhizoma Corydalis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Herba Asari, Oletum Trogopterori, Bulbus Fritillariae Thunbergii, Thallus Laminariae (Thallus Eckloniae), Sargassum, the Radix Aucklandiae combines, each efficacy of drugs is made by these drug regimens to produce synergism, make it that there is depressed liver-energy dispersing and QI regulating, detumescence and apocenosis, blood-activating and qi-promoting, effect of dissipating blood stasis hemostasis, thus effectively can treat Operative complications of breast carcinoma.
The effect of Chinese medicine of the present invention:
Wherein:
Fructus Citri Sarcodactylis: be the dry fruit of rutaceae Fructus Citri Sarcodactylis Citrus medica L. var. sarcodactylis Swingle.Nature and flavor are pungent, bitter, sour, temperature.Return liver, spleen, lung meridian.Effect: liver-smoothing, qi-regulating, and stomach and alleviating pain, dispersing the stagnated live-QI to relieve the stagnation of QI, drying dampness to eliminate phlegm.For stagnation of liver-QI and stomach-QI, distending pain in the chest and hypochondrium, gastral cavilty feeling of fullness, lack of appetite is vomitted.Modern clinical research, Fructus Citri Sarcodactylis quintessence oil has the effect of strengthening to nervous system, and one of three zones is exactly treatment melancholy and anxiety, pacifies indignation, improves the anxiety of women's heart.As neural fatigue, nerve insomnia, worn out mentally and physically time can to releive pressure.But Fructus Citri Sarcodactylis is not excited quintessence oil, it can be inspired enthusiasm and allow mental relaxation.
Fructus Citri: be the dry mature fruit of rutaceae citron Citrus medica L. or fragrant circle Citrus wilsonii Tanaka.Nature and flavor are pungent, bitter, sour, temperature.Return liver, lung, spleen channel.Effect: regulating the flow of QI to ease the stomach, expectorant falls in relieving distension.These product are pungent can manage it loose, and the catharsis of bitter energy, enters Liver Channel and can unclog and readjust irritability and pain relieving.The strongly fragrant distending pain in the chest and hypochondrium for the treatment of the liver, often joins Radix Bupleuri, Radix Curcumae, the equivalent use of Fructus Citri Sarcodactylis.The same Fructus Citri Sarcodactylis of this product merit, but effect is more inferior.Stagnation of QI abdominal distention.
Spina Gleditsiae: be the dry Spina jujubae of leguminous plant Fructus Gleditsia Gleditsia sinensis Lam..Nature and flavor: pungent, temperature.Return lung, Liver Channel.Effect: detumescence and apocenosis, promoting blood circulation by removing wind.Tcm clinical practice is used for swollen ulcer drug all good therapeutic effect, generally shows as the non-Cheng Zheke of pus and disappears, and formed pus person can make it speed and burst.Modern anticancer pharmacological research shows, Spina Gleditsiae has anticancer tumor-suppression activity.Modern pharmacology is studied its decoct flat board and to be burrowed method, has inhibitory action to staphylococcus aureus and micrococcus catarrhalis.It is up that Spina Gleditsiae can draw all medicines, the kind disease controlling the part of the body cavity above the diaphragm housing the heart and lungs.
Flos Lonicerae: the flower that dry flower or band for caprifoliaceae plant Radix Ophiopogonis Lonicera japonica Thunb., Flos Lonicerae Lonicera hypoglauca Miq., Flos Lonicerae (hair calyx Radix Ophiopogonis) Lonicera confusa DC. or hair style Radix Ophiopogonis Lonicera dasystyla Rehd. are just opened.Nature and flavor: sweet, cold.Return lung, the heart, stomach warp.Effect: heat-clearing and toxic substances removing, wind-dispelling heat-dissipating.This product is sweet in flavor and cold in property, can heat-clearing and toxic substances removing, again kind loose carbuncle detumescence, for treating the key medicine of all YANG syndrome carbuncle furuncle.Clinically can in order to carbuncle furunculosis, congestion and swelling pain.Ancient prescription is recorded, and Flos Lonicerae controls all toxic swellings, pays no attention to and does not burst, or from the beginning of heating, and furuncle inguinal bubo, sore throat tonsillitis: Flos Lonicerae (connecting stem and leaf) half bowl, natural juice, decoct eight sub-services it, apply with dregs, relieve internal heat Tuoli, and fall apart gas and blood, and its merit solely wins.
Vascular aurantii: be the grain in the peel of rutaceae orange Citrus reticulata Blanco.Nature and flavor: bitter are flat.Return liver, spleen two warp.Effect: dredging collateral; Regulate the flow of vital energy; Reduce phlegm.Main blockage of meridian-QI; Chronic cough chest pain; Sputum mixed with blood; Get sick from drinking too much wine thirsty.
Rhizoma Chuanxiong: be the dry rhizome of samphire Rhizoma Chuanxiong Ligusticum chuanxiong Hort..Nature and flavor: pungent, temperature.Return liver, gallbladder, heart channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping.The pungent loose temperature of this product is led to, can top, up mountain peak, assigns the sea of blood, outer thorough fur, bypass extremity, can invigorate blood circulation and can circulation of qi promoting, and it is gas medicine in blood that former times people calls Rhizoma Chuanxiong, the functions such as pungent loose, the resolving depression of its residence of dangerous speech, sensible, pain relieving.Rhizoma Chuanxiong has obvious sedation.The in vitro testses such as antibacterial action: Rhizoma Chuanxiong has inhibitory action to large intestine, dysentery (Song Nei Shi), distortion, green pus, typhoid fever, Salmonella paratyphi and vibrio cholera etc.Rhizoma Chuanxiong water logging agent (1:3) also has inhibitory action to some pathogenic dermatophytes in vitro.
Cortex Cinnamomi: be the bark of canella Cortex Cinnamomi Cinnamomum cassia Presl.The large heat of nature and flavor, pungent, sweet.Return kidney, spleen, the heart, Liver Channel.Effect: mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow, promoting blood circulation.Cortex Cinnamomi has warm nutrient blood, helps gasification, the effect that cold expelling is solidifying.Be longer than warming the interior pain relieving, enter the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels and kidney-replenishing, return life fire.
Radix Aconiti Kusnezoffii: be the dried root of ranunculaceae plant Aconitum kusnezoffii Reichb Aconitum kusnezoffii Reichb..Nature and flavor: pungent, bitter, heat; Very toxic.GUIXIN, liver,kidney,spleen warp.Effect: expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Radix Aconiti: be the dry parent root of ranunculaceae plant Aconitum carmichjaelii Debx. Aconitum carmichaeli Debx..Nature and flavor: pungent, bitter, heat; Very toxic.GUIXIN, liver,kidney,spleen warp.Effect: expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Pheretima: be the dry body of Ju Yin section animal Pheretima aspergillum Pheretima aspergillum (E. Perrier), popular Pheretimatschiliensis Pheretima vulgaris Chen, power simulation Pheretima guillelmi (Michaelsen) or comb blind Pheretimatschiliensis Pheretima pectinifera Michaelsen.Nature and flavor: salty, cold.Return liver, spleen, urinary bladder channel.Effect: heat clearing away is calmed the frightened, dredge the meridian passage, clearing heat and relieving dyspnea, relieving stranguria by diuresis.This product is longer than removing obstruction in the collateral to relieve pain, is applicable to blockage of meridian that many reasons causes, blood vessels are smooth, the disease that podomere is unfavorable.Heat clearing away cold in nature, is applicable to the pyretic arthralgia of joint congestion and swelling pain, joint stuffiness especially, with controlling anemofrigid-damp arthralgia, limbs joint is numb, pain more so, the disease such as joint stuffiness, then should with Radix Aconiti, Radix Aconiti Kusnezoffii, etc. expelling wind and cold, removing obstruction in the collateral to relieve pain medicine compatibility.
Bombyx Batryticatus: the larva for Bombycidae insecticide silkworm Bombyx mori Linnaeus. 4 ~ 5 age infects (or artificial vaccination) muscardine Beauveria bassiana(Bals.) Vuillant and lethal larva dry body.Nature and flavor: salty, pungent are flat.Return liver, lung, stomach warp.Effect: expelling wind to relieve convulsion, dissipating phlegm and resolving masses.Cure mainly: apoplectic aphasia, middle tuyere nose eye are oblique.Bombyx Batryticatus also with controlling the diseases such as mastitis, mumps, furuncle carbuncle, can be used with the heat and toxic materials clearing away medicine such as Flos Lonicerae, Radix Scutellariae is same.
Radix Bupleuri: be Umbelliferae herbaceos perennial Radix Bupleuri Bupleurum chinense DC.(Radix Bupleuri) or Radix Bupeuri Scorzonerfolii. Bupleurum scorzonerifolium Willd.(Radix Bupleuri Scorzonerifolii) root or herb.Nature and flavor: bitter, pungent, be slightly cold.Return liver, gallbladder meridian.Effect: reducing fever by reconciliation, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang.Radix Bupleuri has the effect of good dispersing the stagnated live-QI to relieve the stagnation of QI, is the key medicine for the treatment of irritability stasis, to the pain over the hypochondriac region no matter in by stagnation of liver-QI, outer by hindering servant person, all can apply.
Fructus Toosendan: be the dry mature fruit of Meliaceae plant Fructus Toosendan Melia toosendan Sieb. et Zucc..Nature and flavor: bitter, cold; Slightly poisonous.Return liver, small intestinal, urinary bladder channel.Effect: soothing liver-QI promoting the circulation of QI to relieve pain, anthelmintic.For the breast side of body, abdominal distention, colic, abdominal pain due to worm stagnation.
Rhizoma Corydalis: be the dry tuber of papaveraceae plant corydalis Corydalis yanhusuo W. T. Wang.Nature and flavor: acrid, bitter, warm.Return liver, spleen channel.Effect: invigorate blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.The pungent loose temperature of this product is led to, the stagnation of QI in energy promoting the circulation of blood, stasis in gas, blood-activating and qi-promoting pain relieving, and the kind multiple pain controlled caused by stagnation of QI and blood, its analgesic effect is excellent.Record in " book on Chinese herbal medicine is looked for the truth ": Rhizoma Corydalis, no matter being blood is gas, amass and loose person, taking this power can be sensible, warm in nature with it, then can manage it in QI and blood can be smooth, and acrid in the mouth then can moisten can fall apart in QI and blood, so manage upper and lower all pains all over the body, merit of often walking alone is many.
Herba Scutellariae Barbatae: be the dry herb of labiate Herba Scutellariae Barbatae Scutellaria barbata D. Don.Nature and flavor: pungent, bitter, cold.Return lung, liver, kidney channel.Effect: heat-clearing and toxic substances removing, dissipating blood stasis stops blooding, inducing diuresis to remove edema.
Herba Hedyotidis Diffusae: be the herb of Rubiaceae plants of Hedyotis Herba Hedyotidis Diffusae Hedyotis diffusa Willd. [Oldenlandia diffusa (Willd.) Roxb.].Nature and flavor: sweet, light, cool.Enter stomach, large intestine, small intestine meridian.Effect: heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain.Furuncle carbuncle is controlled in external, has comparatively high inhibition effect in vitro to the tumor cell of acute lymphoblastic type, granulocyte type, monocyte type and chronic granulocyte type.
Herba Asari: be aristolochiaceae plant Herba Asari Asarum heterotropoides Fr. Schmidt var.mandshuricum(Maxim.) the dry herb of Kitag., Seoul Herba Asari Asarum sieboldii Miq. var. seoulense Nakai or magnificent Herba Asari Asarum sieboldii Miq..Nature and flavor are pungent; Temperature; Mild toxicity.Return lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel.Effect: mass dissipating and swelling eliminating; Induce sweat cold expelling; Wind-expelling pain-stopping; Warming the lung to resolve fluid-retention; The therapeutic method to keep the adverse QI flowing downwards is eliminated the phlegm, sensible.Antibacterial, antivirus action kakuol preserved material, volatilization wet goods have certain In-vitro Inhibitory Effect to gram positive bacteria, bacillus subtilis and Bacillus typhi, and decoct also has inhibitory action to tubercule bacillus and Bacillus typhi.The pungent perfume (or spice) of Herba Asari is walked to alter, and has good cold-dispelling, the effect of the pain that relieves the pain.
Oletum Trogopterori: be flying squirrel section animal trogopterus xanthipes Trogopterus Xanthipes Milne-Edwards or the dry feces flying murine little flying squirrel Pteromys volans L..Nature and flavor: sweet, temperature.Enter liver, spleen channel.Effect: promoting blood circulation to remove blood stasis, parch to black stops blooding.Have a pain for trusted subordinate's congestion, dysmenorrhea, blood stasis amenorrhea, puerperal abdominalgia with blood stasis; Parch to black controls metrostaxis; Traumatic injury is controlled in external, Serpentis, insect bite wound.
Bulbus Fritillariae Thunbergii: be the dry bulb of liliaceous plant Bulbus Fritillariae Thunbergii Fritillaria thunbergii Miq..Nature and flavor: bitter, cold.Return lung, heart channel.Effect: heat clearing away eliminating stagnation, preventing phlegm from forming and stopping coughing.For wind-heat invading the lung, phlegm-fire cough, lung abscess, acute mastitis, scrofula, sore." book on Chinese herbal medicine is just " is recorded: fall mental disorder most, kind relieving stagnation, and relieve the pain pain, and relieving distension is full, clearing away liver-fire, improve visual and auditory acuity, except seasonal epidemic pathogens dysphoria with smothery sensation, and jaundice stranguria with urinary obstruction, hematuria of having blood in stool; Relieving heat toxin, kill parasites and treat sore throat, scrofula, acute mastitis carbuncle on the back, all carbuncle and ulcer toxic swellings, damp and hot malignant boil, anal fistula, incised wound is hemorrhage, burn pain, and than Bulbus Fritillariae Cirrhosae, the merit of falling clearly, not less than several times.
Thallus Laminariae (Thallus Eckloniae): be the dry thallus of Laminariaceae plant Thallus Laminariae (Thallus Eckloniae) Laminaria japonica Aresch. or Alariaceae plant Thallus Laminariae (Thallus Eckloniae) Ecklonia kurome Okam..Nature and flavor are salty, cold; Nontoxic.Return liver, stomach, kidney channel.Effect: eliminating phlegm and softening indurated mass, diuretic detumescent.Sargassum and Thallus Laminariae (Thallus Eckloniae) mutual reinforcement between are use, eliminating phlegm and softening indurated mass, and the effect of diuretic detumescent strengthens, and may be used for dissipation tumor.
Sargassum: be Sargassaceae plant Sargassum Sargassum pallidum(Turn.) the dry frond of C. Ag. or Sargassum fusiforme (Harv.) Setch Sargassum fusiforme (Harv.) Setch..Nature and flavor are bitter, salty, cold.Return lung, spleen, kidney, liver, stomach warp.Effect: eliminating phlegm and softening indurated mass, diuretic detumescent.
The Radix Aucklandiae: be the dry root of feverfew Radix Aucklandiae Aucklandia lappa Decne..Nature and flavor: pungent, bitter, temperature.Return spleen, stomach, large intestine, three burnt, gallbladder meridians.Effect: promoting the circulation of QI to relieve pain, strengthening the spleen to promote digestion.In addition edema, stranguria with urinary obstruction, carbuncle sore, traumatic injury etc., be shown in there is swollen, swollen, pain person, all can select.
Side's solution of the present invention is: Fructus Citri Sarcodactylis depressed liver-energy dispersing and QI regulating, drying dampness to eliminate phlegm in side, expectorant falls in Fructus Citri regulating the flow of QI to ease the stomach, relieving distension, Spina Gleditsiae detumescence and apocenosis, promoting blood circulation by removing wind, Flos Lonicerae heat-clearing and toxic substances removing, Vascular aurantii regulating qi and dredging collateral, the above five tastes are monarch drug altogether, effect of long memorial liver and qi, detumescence and apocenosis altogether, complication maximum after mammary cancer surgery is exactly edema of the upper extremity, monarch drug fundamentally carries out regulating qi and dredging collateral, inducing diuresis to remove edema from focus, and effect that monarch drug has promoting blood circulation by removing wind more, alleviating distention in middle-JIAO is regulated the flow of vital energy, can alleviate patient's anxiety after mammary cancer surgery, depressed symptom.Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping, Cortex Cinnamomi dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow, Radix Aconiti Kusnezoffii, Radix Aconiti expelling wind and removing dampness, antalgic, Pheretima dredge the meridian passage, relieving stranguria by diuresis, Bombyx Batryticatus dissipating phlegm and resolving masses, Radix Bupleuri dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, above seven tastes are ministerial drug altogether, assist a ruler in governing a country effect that monarch drug strengthens dredge the meridian passage, dissipating phlegm and resolving masses on the one hand, blood-activating and qi-promoting, dispersing cold for relieving pain, ascending up spleen-Qi and Yang on the other hand, promote skin incisional wounds healing, prevent flap necrosis, the recovery of patient after quickening mammary cancer surgery.Fructus Toosendan promoting the circulation of QI to relieve pain, the pain relieving of Rhizoma Corydalis blood circulation promoting regulates qi, Herba Scutellariae Barbatae, the hemostasis of Herba Hedyotidis Diffusae dissipating blood stasis, inducing diuresis to remove edema, Herba Asari dispersing swelling and dissipating binds, wind-expelling pain-stopping, Oletum Trogopterori promoting blood circulation to remove blood stasis, Bulbus Fritillariae Thunbergii heat clearing away eliminating stagnation, Thallus Laminariae (Thallus Eckloniae), Sargassum eliminating phlegm and softening indurated mass, diuretic detumescent, Radix Aucklandiae promoting the circulation of QI to relieve pain, above a few taste is adjuvant drug altogether, strengthens monarch drug, the ministerial drug efficacy of a drug, eliminate Post operation hydrops, edema existing, accelerate postoperative recovery.The all medicines of this side share, and the monarch and his subjects pull together, and assistant makes auxiliary altogether, have effect of depressed liver-energy dispersing and QI regulating, detumescence and apocenosis, blood-activating and qi-promoting, dissipating blood stasis hemostasis, effectively can treat Operative complications of breast carcinoma.
Medicine material consumption of the present invention is groped to sum up to draw through inventor in a large number, each raw material dosage is for all to have good curative effect in following weight parts scope: Fructus Citri Sarcodactylis 10-20 part, Fructus Citri 10-20 part, Spina Gleditsiae 13-23 part, Flos Lonicerae 10-20 part, Vascular aurantii 13-23 part, Rhizoma Chuanxiong 10-20 part, Cortex Cinnamomi 4-14 part, Radix Aconiti Kusnezoffii 7-17 part, Radix Aconiti 7-17 part, Pheretima 4-14 part, Bombyx Batryticatus 4-14 part, Radix Bupleuri 10-20 part, Fructus Toosendan 10-20 part, Rhizoma Corydalis 25-35 part, Herba Scutellariae Barbatae 25-35 part, Herba Hedyotidis Diffusae 25-35 part, Herba Asari 3-9 part, Oletum Trogopterori 5-15 part, Bulbus Fritillariae Thunbergii 10-20 part, Thallus Laminariae (Thallus Eckloniae) 10-20 part, Sargassum 10-20 part, Radix Aucklandiae 7-17 part.
Wherein be preferably: Fructus Citri Sarcodactylis 15 parts, Fructus Citri 15 parts, Spina Gleditsiae 18 parts, Flos Lonicerae 15 parts, Vascular aurantii 18 parts, Rhizoma Chuanxiong 15 parts, Cortex Cinnamomi 9 parts, Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti 12 parts, Pheretima 9 parts, Bombyx Batryticatus 9 parts, Radix Bupleuri 15 parts, Fructus Toosendan 15 parts, Rhizoma Corydalis 30 parts, Herba Scutellariae Barbatae 30 parts, Herba Hedyotidis Diffusae 30 parts, Herba Asari 6 parts, Oletum Trogopterori 10 parts, Bulbus Fritillariae Thunbergii 15 parts, Thallus Laminariae (Thallus Eckloniae) 15 parts, Sargassum 15 parts, the Radix Aucklandiae 12 parts.
A kind of preparation method of the Chinese medicine preparation for Mammary cancer is as follows:
Step one: according to weight proportion of the present invention, becomes medicated bag by Fructus Toosendan, Oletum Trogopterori bundle, adds Fructus Citri Sarcodactylis, Fructus Citri is put in water and soaks about 45 minutes, filters, for subsequent use;
Step 2: by weight proportion of the present invention, takes Pheretima, Bombyx Batryticatus pulverizing is ground to 120 mesh sieves, for subsequent use;
Step 3: by weight proportion of the present invention, take Rhizoma Chuanxiong, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Radix Aconiti, the Radix Aucklandiae is put into after marmite adds step one immersion and is remained cold water, exceed powder 3 ~ 4 li centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, add Spina Gleditsiae, Radix Bupleuri, Rhizoma Corydalis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Herba Asari, Bulbus Fritillariae Thunbergii, Thallus Laminariae (Thallus Eckloniae), medicated bag and soaked Fructus Citri Sarcodactylis in Sargassum and step one, Fructus Citri, decoct 20 minutes, finally add Flos Lonicerae, Vascular aurantii decocts 10 minutes, filter, waste, for subsequent use,
Step 4: twice filtrate in step 3 is merged, adds the powder in step 2 while hot, stir, both the external-use lotion for the treatment of Operative complications of breast carcinoma of the present invention.
This pharmaceutical preparation using method is: the medicinal liquid be fried open can fumigate affected part while hot, cleans when water temperature is suitable.
Medicine of the present invention has the effects such as depressed liver-energy dispersing and QI regulating, detumescence and apocenosis, blood-activating and qi-promoting, dissipating blood stasis hemostasis, and determined curative effect, cheap, healing time is short, and method is simple.According to clinical 200 routine patient view statistics, use specific embodiment of the invention medicine one the total effective rate course for the treatment of 85%, two the total effective rate course for the treatment of 94%.
Detailed description of the invention
Embodiment one, Fructus Citri Sarcodactylis 10 parts, Fructus Citri 10 parts, Spina Gleditsiae 13 parts, Flos Lonicerae 10 parts, Vascular aurantii 13 parts, Rhizoma Chuanxiong 10 parts, Cortex Cinnamomi 4 parts, Radix Aconiti Kusnezoffii 7 parts, Radix Aconiti 7 parts, Pheretima 4 parts, Bombyx Batryticatus 4 parts, Radix Bupleuri 10 parts, Fructus Toosendan 10 parts, Rhizoma Corydalis 25 parts, Herba Scutellariae Barbatae 25 parts, Herba Hedyotidis Diffusae 25 parts, Herba Asari 3 parts, Oletum Trogopterori 5 parts, Bulbus Fritillariae Thunbergii 10 parts, Thallus Laminariae (Thallus Eckloniae) 10 parts, Sargassum 10 parts, the Radix Aucklandiae 7 parts.
Embodiment two, Fructus Citri Sarcodactylis 15 parts, Fructus Citri 15 parts, Spina Gleditsiae 18 parts, Flos Lonicerae 15 parts, Vascular aurantii 18 parts, Rhizoma Chuanxiong 15 parts, Cortex Cinnamomi 9 parts, Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti 12 parts, Pheretima 9 parts, Bombyx Batryticatus 9 parts, Radix Bupleuri 15 parts, Fructus Toosendan 15 parts, Rhizoma Corydalis 30 parts, Herba Scutellariae Barbatae 30 parts, Herba Hedyotidis Diffusae 30 parts, Herba Asari 6 parts, Oletum Trogopterori 10 parts, Bulbus Fritillariae Thunbergii 15 parts, Thallus Laminariae (Thallus Eckloniae) 15 parts, Sargassum 15 parts, the Radix Aucklandiae 12 parts.
Embodiment three, Fructus Citri Sarcodactylis 20 parts, Fructus Citri 20 parts, Spina Gleditsiae 23 parts, Flos Lonicerae 20 parts, Vascular aurantii 23 parts, Rhizoma Chuanxiong 20 parts, Cortex Cinnamomi 14 parts, Radix Aconiti Kusnezoffii 17 parts, Radix Aconiti 17 parts, Pheretima 14 parts, Bombyx Batryticatus 14 parts, Radix Bupleuri 20 parts, Fructus Toosendan 20 parts, Rhizoma Corydalis 35 parts, Herba Scutellariae Barbatae 35 parts, Herba Hedyotidis Diffusae 35 parts, Herba Asari 9 parts, Oletum Trogopterori 15 parts, Bulbus Fritillariae Thunbergii 20 parts, Thallus Laminariae (Thallus Eckloniae) 20 parts, Sargassum 20 parts, the Radix Aucklandiae 17 parts.
Here is the clinical statistics data that patient uses medicine of the present invention:
One, physical data
Treatment patient 200 example, 43 years old mean age.
Two, Therapeutic Method
According to Medications Example two of the present invention, and the external-use lotion that preferred preparation method is made, the medicinal liquid be fried open can fumigate affected part while hot, cleans when water temperature is suitable.Every day 2 times 10 days is a course for the treatment of.
Three, efficacy assessment standard
1, cure: patient's edema of the upper extremity phenomenon disappears, hemorrhage, flap necrosis phenomenon recovery from illness, and other clinical symptoms disappear completely.
2, take a turn for the better: patient's edema of the upper extremity phenomenon is controlled, and takes a turn for the better to some extent, the symptoms such as hemorrhage, flap necrosis are eased, and other clinical symptoms are all eased.
3, do not heal: the complication after mammary cancer surgery is without any improvement.
Four, therapeutic outcome statistics
Wherein: total effective rate=cure rate+improvement rate
Shown by the statistics of therapeutic outcome, Chinese medicine of the present invention has good clinical effectiveness in treatment Operative complications of breast carcinoma, effectively can improve the cure rate for the treatment of, be worth promoting in clinical practice.
Model case and curative effect:
Case one, Lee, female, 41 years old, right breast generation breast carcinoma, hospital is gone to carry out excision, Post operation 3 days is not owing to affording to do expensive hospitalization cost, leave hospital, be in not in a few days, patient's upper limb starts edema, and slightly bleeding, in patient family, economic condition is really difficult, hospital is not gone to give treatment to, upon somebody's introduction, come here to go to a doctor, adopt case method of the present invention, washout affected part, after using two courses for the treatment of, Mammary cancer edema phenomenon disappears gradually, bleeding takes a turn for the better completely, a course for the treatment of of rear continuation use, patient's edema of the upper extremity phenomenon disappears completely, and patient wound heals, situation is also fine, recovery from illness.
Case two, Zhang, female, 50 years old, patient's left breast IDC, just start to carry out chemicotherapy treatment, but along with sb.'s illness took a turn for the worse, need to carry out operative treatment, after corrective surgery in a couple of days, there is the phenomenon of flap necrosis and edema of the upper extremity, hospital adopts intravenous drip diuretic, but poor effect, until patient discharge, edema of the upper extremity phenomenon hampers orthobiosis, went to a doctor in here afterwards, adopt case two method of the present invention, washout affected part, after using two courses for the treatment of, patient's upper limb can activity freely, edema phenomenon obviously disappears, continue two courses for the treatment of of use, patient's edema of the upper extremity phenomenon thoroughly disappears, other complication of Post operation also do not occur, recovery from illness.
Claims (4)
1. the Chinese medicine composition for Mammary cancer, it is characterized in that, this Chinese medicine composition is made up of the medicine of following weight portion: Fructus Citri Sarcodactylis 10-20 part, Fructus Citri 10-20 part, Spina Gleditsiae 13-23 part, Flos Lonicerae 10-20 part, Vascular aurantii 13-23 part, Rhizoma Chuanxiong 10-20 part, Cortex Cinnamomi 4-14 part, Radix Aconiti Kusnezoffii 7-17 part, Radix Aconiti 7-17 part, Pheretima 4-14 part, Bombyx Batryticatus 4-14 part, Radix Bupleuri 10-20 part, Fructus Toosendan 10-20 part, Rhizoma Corydalis 25-35 part, Herba Scutellariae Barbatae 25-35 part, Herba Hedyotidis Diffusae 25-35 part, Herba Asari 3-9 part, Oletum Trogopterori 5-15 part, Bulbus Fritillariae Thunbergii 10-20 part, Thallus Laminariae (Thallus Eckloniae) 10-20 part, Sargassum 10-20 part, Radix Aucklandiae 7-17 part.
2. the Chinese medicine composition for Mammary cancer according to claims 1, it is characterized in that, be made up of the medicine of following weight portion: Fructus Citri Sarcodactylis 15 parts, Fructus Citri 15 parts, Spina Gleditsiae 18 parts, Flos Lonicerae 15 parts, Vascular aurantii 18 parts, Rhizoma Chuanxiong 15 parts, Cortex Cinnamomi 9 parts, Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti 12 parts, Pheretima 9 parts, Bombyx Batryticatus 9 parts, Radix Bupleuri 15 parts, Fructus Toosendan 15 parts, Rhizoma Corydalis 30 parts, Herba Scutellariae Barbatae 30 parts, Herba Hedyotidis Diffusae 30 parts, Herba Asari 6 parts, Oletum Trogopterori 10 parts, Bulbus Fritillariae Thunbergii 15 parts, Thallus Laminariae (Thallus Eckloniae) 15 parts, Sargassum 15 parts, the Radix Aucklandiae 12 parts.
3. the Chinese medicine preparation for Mammary cancer according to claim 1 and 2, is characterized in that: described Chinese medicine preparation is external-use lotion.
4. for a preparation method for the Chinese medicine preparation of Mammary cancer, it is characterized in that, preparation method is as follows: step one: according to weight proportion of the present invention, Fructus Toosendan, Oletum Trogopterori bundle are become medicated bag, add Fructus Citri Sarcodactylis, Fructus Citri is put in water and soaks about 45 minutes, filter, for subsequent use, step 2: by weight proportion of the present invention, takes Pheretima, Bombyx Batryticatus pulverizing is ground to 120 mesh sieves, for subsequent use, step 3: by weight proportion of the present invention, take Rhizoma Chuanxiong, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Radix Aconiti, the Radix Aucklandiae is put into after marmite adds step one immersion and is remained cold water, exceed powder 3 ~ 4 li centimetres, after being fried boiling with high heat, again with 20 ~ 30 minutes at a simmer, filter, obtain filtrate, the water of 3 cm is added in residue medicinal residues, add Spina Gleditsiae, Radix Bupleuri, Rhizoma Corydalis, Herba Scutellariae Barbatae, Herba Hedyotidis Diffusae, Herba Asari, Bulbus Fritillariae Thunbergii, Thallus Laminariae (Thallus Eckloniae), medicated bag and soaked Fructus Citri Sarcodactylis in Sargassum and step one, Fructus Citri, decoct 20 minutes, finally add Flos Lonicerae, Vascular aurantii decocts 10 minutes, filter, waste, for subsequent use, step 4: twice filtrate in step 3 is merged, adds the powder in step 2 while hot, stir, both the external-use lotion for the treatment of Operative complications of breast carcinoma of the present invention.
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| CN1198941A (en) * | 1998-06-08 | 1998-11-18 | 信国峰 | 'Kangruling' medicine mixture |
| US20100028461A1 (en) * | 2003-07-16 | 2010-02-04 | Tzu Chi Buddhist General Hospital | Gamma-butyrolactone compound and pharmaceutical composition thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1198941A (en) * | 1998-06-08 | 1998-11-18 | 信国峰 | 'Kangruling' medicine mixture |
| US20100028461A1 (en) * | 2003-07-16 | 2010-02-04 | Tzu Chi Buddhist General Hospital | Gamma-butyrolactone compound and pharmaceutical composition thereof |
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| 王骁: "张新渝老师治疗乳腺癌根治术后单纯性上肢肿胀经验介绍", 《新中医》 * |
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Application publication date: 20150325 |