CN104435509B - A kind of Chinese medicine composition for treating newborn addiction and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating newborn addiction and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine composition for treating newborn addiction, the primary raw material of following weight proportions is taken to be prepared from：15 30 parts of Artemisia anomala, 20 30 parts of row night, 18 25 parts of latifolious rush rhizome, 10 20 parts of rascal, 9 28 parts of caulis clematidis armandii, 30 40 parts of the bighead atractylodes rhizome, 25 40 parts of Ligusticum wallichii, 9 18 parts of radix bupleuri, 6 14 parts of safflower, 15 28 parts of rhizoma cyperi.Chinese medicine composition of the present invention meets the principle that traditional Chinese medicine debates disease treatment.The medicinal material of selection is divided into particle for oral administration and external application application volatile oil, inside and outside to treat simultaneously, treats more comprehensive, rapider, lasting medicine is administered in affected area, belongs to inside and outside and take into account, the newborn addiction prescription treated both principal and secondary aspect of disease.The Chinese medicinal material of selection has promoting blood circulation and removing blood stasis, relaxes the muscles and stimulate the blood circulation, the effect of qi-regulating with, and cheap, and the financial burden for also not resulting in patient is used for a long time, and is the ideal medicine of the newborn addiction for the treatment of.
Description
Technical field
The invention belongs to traditional Chinese medicine field, it is related to a kind of Chinese medicine composition for treating newborn addiction and preparation method thereof.
Background technology
Newborn addiction：Disease of tcm name, refers to the common chronic benign lump in female breast portion, based on lump in breast and distending pain
Disease, is common in young women.Newborn addiction is found in hyperplasia of mammary glands, Cystic hyperplasia of breast, mastofibroma of western medicine etc.
Disease.Western medicine thinks that cyclomastopathy is relevant with ovarian dysfunction, and such as lutern, which is secreted, to be reduced, the Secretion pair of estrogen
Increase.
This disease is how angry relevant with feelings will internal injury, troubled thoughts.Stomach of foot Yang Ming passes through under breast, the liver channel of foot-Jueyin to breast, and foot is too
Cloudy the spleen channel row breast is outer, if feelings will internal injury, and angry then liver and spleen pent-up of being worried, qi and blood is inverse disorderly, and the not all right Tianjin of gas, body fluid is condensed into phlegm；It is multiple
Because of liver Wood restricts earth, spleen is caused to transport wet, stomach can not drop turbid, then the turbid interior life of phlegm；Turbid hinder in newborn network of stagnation of the circulation of vital energy phlegm is then lump pain.Eight
Arteries and veins is subordinate in liver kidney, and chong channel is subordinate in positive bright, if liver depression forming fire, consumes the moon of liver kidney, then Chong and Ren channel disorder,《General Records of Holy Universal Relief》Cloud：" punching is appointed
Two warps, are above milk, and lower is moon water." so this disease is how related to the menstrual cycle.This sick basic pathogenesis is solidifying for stagnation of the circulation of vital energy phlegm, punching
Appoint imbalance, disease is passed through in stomach, liver, spleen three.There is shape lump not of uniform size with breast, pain is related as mainly with the menstrual cycle
The mastosis class disease of performance.
This disease is more common in 20-40 Sui women, show as unilateral or bilateral breast occur it is single or multiple differ in size it is swollen
Block, distending pain or tenderness, surface are smooth, clear border, push away movable, increases slowly, strong but pliable in texture or sexy in capsule.It is simultaneous to see lump
Often disappear elder because liking anger with distending pain, card category stagnation of the circulation of vital energy phlegm coagulates；Then it is punching if often being aggravated before menstruation comes, alleviator after menstruation
Appoint imbalance.Majority has a flat lump in breast outside upper quadrant, and that lays one's hand on has the tough hard tubercle of beans size, can there is tenderness, lump side
Boundary owes clear, with surrounding tissue adhesion.Breast can have distending pain or shouting pain, anger of often joining in charitable and pious deeds and growth and decline, and the moon is premenstrual to be aggravated, and is delayed after menstruation
Solution.
The Syndrome Types of TCM of newborn addiction is a lot of, point two types having, point three types having, until four types, five types, six types, seven types etc., very
Or more.What is had is excessively simple, and what is had is too numerous.But always coagulated nothing more than stagnation of QI due to depression of the liver, stagnation of the circulation of vital energy phlegm, blood stasis phlegm is solidifying, discord, a spleen kidney yang are appointed in punching
Void, the deficiency of liver-yin and kidney-yin, qi-blood deficiency etc..Though the opinion of each family is not the same, its interpretation of the cause, onset and process of an illness all be unable to do without above-mentioned viewpoint.Li Jimin
Doctor treats newborn addiction (cyclomastopathy), and clinically the dialectical four types progress opinion that is divided into is controlled.
1. stagnation of QI due to depression of the liver：Liver depression is not relaxed, breast fullness, and caking distending pain is joined in charitable and pious deeds anger growth and decline, when have shouting pain, two side of body distending pains, mouth
Bitter irritated, pale tongue with thin fur is white, veins string or thin string.2. Chong and Ren channel disorder：Breast lumps, secret anguish or shouting pain, fixed pain.Premenstrual lump
Significantly increase, reduce after and soften, or with the disease such as irregular menstruation, dysmenorrhoea, infertile.Pink tongue tongue is white, and arteries and veins carefully moistens.3. insufficiency of the spleen phlegm
It is solidifying：Lump in breast is larger, but slow-growing, and matter heavily fortified point distending pain, surface is smooth, and what is pushed away is removable, and clear border, mammary contour is constant.
Thin white fur of tongue, wiry and rolling pulse.Kidney deficiency blood stasis：With the passing of time breast is lumpd, and shouting pain or has a dull ache, and sore spot is fixed.It is weak with the soreness of waist, through water
Less and color is light, or the disease such as amenorrhoea, infertile.Tongue is dark or there are petechia, the thin white, deep thready pulse of tongue in tongue side.
In the method for the newborn addiction of existing treatment, the B of Authorization Notice No. CN 102671113 (application number 201210066880.3)
Patent disclose a kind of preparation method for the Chinese medicine composition for treating newborn addiction, take the crude drug of following parts by weight：Oyster 130-
160 parts, 210-250 parts of the Radix Astragali, 20-40 parts of Rhizoma Sparganii, 20-30 parts of malt, 140-170 parts of asparagus fern, 50-70 parts of myrrh, barrenwort
140-170 parts, 140-170 parts of the red sage root, 20-40 parts of the bighead atractylodes rhizome, 140-170 parts of marine alga, 20-40 parts of radix bupleuri, 20-40 parts of curcuma zedoary, chicken
Interior golden 30-50 parts, 20-40 parts of rascal, 20-40 parts of frankincense；Authorization Notice No. CN 101244177B's (200810049393.X)
Patent disclose a kind of newborn addiction dissipate and preparation method thereof, by 3-5 grams of scorpio, 3-5 grams of rhizoma cyperi, 3-5 grams of blood clam, 3-5 grams of safflower,
Full Snakegourd Fruit 400-500 restrains into；Its preparation method is realized by following steps：First by 3-5 grams of scorpio, 3-5 grams of rhizoma cyperi, watt
Stupefied sub- 3-5 grams, 3-5 grams of safflower be ground into powder, secondly fresh full 400-500 grams of Snakegourd Fruit is added water is brewed into flowing soaking paste, then
Dried, be made powdered, finally the powder of said medicine is well mixed, that is, the present invention is made.
Chinese medicine has good curative effect in the newborn addiction for the treatment of as can be seen here, but at present in the medicine of the newborn addiction of existing treatment,
General comparitive study is single, and therapeutic effect is also bad, and extra burden can be caused to the body of patient.
The content of the invention
For the present situation that the newborn addiction of existing treatment is not enough, an object of the present invention is to provide a kind of Chinese medicine for treating newborn addiction
Composition, with easy to carry, action effect substantially, can be quickly play effect promoting blood circulation and removing blood stasis, and it is using in the localities
Relatively conventional Chinese medicine is with low cost as raw material.
Another object of the present invention is just to provide the preparation method of above-mentioned Chinese medicine composition.
The above-mentioned purpose of the present invention is achieved through the following technical solutions：
A kind of Chinese medicine composition for treating newborn addiction, takes the primary raw material of following weight proportions to be prepared from：Artemisia anomala 15-30
Part, night 20-30 parts of row, 18-25 parts of latifolious rush rhizome, 10-20 parts of rascal, 9-28 parts of caulis clematidis armandii, 30-40 parts of the bighead atractylodes rhizome, Ligusticum wallichii 25-40
Part, 9-18 parts of radix bupleuri, 6-14 parts of safflower, 15-28 parts of rhizoma cyperi.
A kind of Chinese medicine composition for treating newborn addiction, optimum ratio takes the primary raw material of following weight proportions to be prepared from：Liu
Post 23-26 parts of slave, night 23-28 parts of row, 20-22 parts of latifolious rush rhizome, 13-18 parts of rascal, 15-18 parts of caulis clematidis armandii, 33-38 parts of the bighead atractylodes rhizome,
30-35 parts of Ligusticum wallichii, 13-15 parts of radix bupleuri, 9-11 parts of safflower, 23-25 parts of rhizoma cyperi.
A kind of Chinese medicine composition for treating newborn addiction, more preferably preferred proportioning takes the primary raw material of following weight proportions to prepare
Form：24 parts of Artemisia anomala, 25 parts of row night, 21 parts of latifolious rush rhizome, 15 parts of rascal, 16 parts of caulis clematidis armandii, 35 parts of the bighead atractylodes rhizome, 33 parts of Ligusticum wallichii, bavin
14 parts recklessly, 10 parts of safflower, 24 parts of rhizoma cyperi.
The preparation method of above-mentioned Chinese medicine composition, scheme preferably is：Step is as follows：
(1) Artemisia anomala, latifolious rush rhizome, rascal and caulis clematidis armandii are dried 20-40 minutes slowly as low baking temperature on tile, taking-up dries in the air cool,
Mortar pulverization is used, 130-150 mesh sieves (preferably crossing 140 mesh sieves) are crossed；
(2) row night, radix bupleuri and rhizoma cyperi are placed in non iron container, add the vexed profit of light-coloured vinegar, the consumption of light-coloured vinegar is row night, bavin
Recklessly with 1-3 times of the total consumption of rhizoma cyperi；
(3) bulk drug obtained by step (2) is soaked 30 minutes, water consumption is 1-5 times of bulk drug weight, 80 DEG C with
Upper water extraction 40-80 minutes (preferably water extraction 60 minutes), crosses 100-200 mesh screen packs, obtains decoction；
(4) by medicine liquid heating obtained by step (3) to seething with excitement, continue to filter after 1.5 hours, filtrate is concentrated into relative density and is
1.20, let cool；
(5) gained smalls in step (1) is added in filtrate obtained by step (4), dries, particle is made；
(6) bighead atractylodes rhizome, Ligusticum wallichii were smashed into 80-120 mesh sieves (preferably 100 mesh sieves), plus 30-40 DEG C of warm water soaks 30 points
Clock, intense fire is fried open, and is turned slow fire heating distillation equipment and is collected distillate or be passed through steam distillation 50-70 minutes, makes volatile oil
Together distilled with water, collect distillate, stand 30 minutes, distillate, which is cooled to after 40 DEG C, takes upper strata fluid, added in fluid
Enter safflower and be heated to 80 DEG C -150 DEG C, keep 6 minutes sterilizings, be cooled to room temperature, after be distributed into air-tight bottle and obtain external application application
Volatile oil.
Above-mentioned preparation method, scheme preferably is：Step (1) by Artemisia anomala, latifolious rush rhizome, rascal and caulis clematidis armandii as watt
Low baking temperature dries 25-35 minutes (preferably 30 minutes) slowly on piece.
Above-mentioned preparation method, scheme preferably is：The consumption of step (2) light-coloured vinegar is row night, radix bupleuri and the total consumption of rhizoma cyperi
1.5-2.5 times (preferably 2 times).
Above-mentioned preparation method, scheme preferably is：Step (3) water consumption is 2-4 times (preferably 3 of bulk drug weight
Times).
Above-mentioned preparation method, scheme preferably is：Step (3) crosses 140-180 mesh screen pack, and (preferably 160 mesh are filtered
Net).
Above-mentioned preparation method, scheme preferably is：Step (6) is passed through steam distillation 55-65 minutes (preferably 60 points
Clock).
Above-mentioned preparation method, scheme preferably is：Safflower is added in step (6) fluid and is heated to 100-130 DEG C (preferably
It is heated to 120 DEG C).
Application method：To make the present invention reach optimum therapeuticing effect, gained granule is taken after 1 hour after the meal three, used
Warm boiled water, each 3-5 grams, gained external application application volatile oil is applied at mammary swelling, and one for several times, appropriate every time, is within 7 days
One course for the treatment of.
The Chinese medicine composition is notable to the effect of newborn addiction, and not only promoting blood circulation and removing blood stasis, moreover it is possible to relax the muscles and stimulate the blood circulation, recuperating qi-blood improves
Patient is for a long time because of the slight illness that newborn addiction is brought, and the optionally common medicinal materials in side more than the present invention, cheap, alleviates the economy of patient
Burden.
A kind of Chinese medicine composition for treating newborn addiction, the pharmacological effect of each bulk drug is respectively：
Artemisia anomala：Also known as Artemisia anomala grass, Herba Senecionis Scandentis, it is the wounded in the battle herb of composite family sagebruss artemisia anomalas.The property of medicine：Stem cylinder
Shape, surface brown color or brown-green, matter are hard and crisp, frangibility, the integrated spike panicle of capitulum, withered yellow, gas fragrance,
It is bitter, pungent, it is warm-natured.Composition：Mainly contain arteanoflavone, tricin, apiolin, palmitic acid etc..According to modern pharmacological research
It was found that, the medical instrument has functions that anti anoxia, promoting blood circulation and removing blood stasis, disperse accumulations, hemostasia and detumescence, for amenorrhea due to stagnation of blood, dyspeptic abdominalgia, hematuria,
The diseases such as scald.
Row night：Base：The full worm that cape belongs to animal tiger spot cloth cape is walked for Carabidae.The property of medicine：It is pungent, temperature.Function is cured mainly：Promoting blood circulation
Stagnation resolvation, eliminating stagnation to stop pain.Cure mainly amenorrhea due to stagnation of blood, dysmenorrhoea, postpartum stasis of blood, a lump in the abdomen causing distension and pain, bruise stasis caused pain.
Latifolious rush rhizome：Base：The rhizome of stem rush is walked for rush family sharp-flowered rush plant.The property of medicine：It is mild-natured, it is pungent, micro-
It is bitter.Function is cured mainly：Regulating qi-flowing for relieving pain, regulating menstruation and activating blood is cured mainly under stagnation of QI due to depression of the liver, pain in chest and hypochondrium, menstrual disorder, metrorrhagia band.
Rascal：Base：For Rutaceae citrus tree plant tangerine and its young fruit or the pericarp of immature fruit of variety.Into
Point：Rascal active ingredient containing boosting：Left-handed synephrine acetate；Also contain aspartic acid, glutamic acid, proline, glycine, the third ammonia
Acid, cystine, leucine, isoleucine, phenylalanine etc..The property of medicine：It is bitter, pungent, temperature.Return liver, courage, stomach.Function is cured mainly：It is soothing the liver
Relieving stagnant Qi, disperse accumulationsization is stagnant.Cure mainly side of body rib, breast, epigastric distending pain, newborn core, acute mastitis, hernia, dyspepsia, a lump in the abdomen causing distension and pain, chronic malaria addiction block.
Caulis clematidis armandii：Base：For the rattan of Ranunculaceae Actions of Clematis Species mandarin clematis herb, Clematis montana etc..Composition：1. mandarin clematis herb contains
Brass methods of glycosides：Root of Chinese clematis glycosides.2. Clematis montana contains the six sugared saponin(es and trisaccharide saponin(e using hederagenin as aglycon.Medicine
Property：Light, slight bitter, trembles with fear.Function is cured mainly：Reducing fever and causing diuresis, stimulate the menstrual flow lower breast.The damp and hot retention of urine is cured mainly, oedema, stranguria, aphthae is damp and hot
Numbness pain, articular instability, married woman's amenorrhoea, alactation.
The bighead atractylodes rhizome：Nature and flavor：It is bitter, sweet, temperature.Channel tropism：Returns spleen, stomach.Effect：Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis is antiabortive.It is main
Control：For spleen eating less, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability.Rhizoma Atractylodis Macrocephalae invigorating the spleen, and stomach, it is antiabortive.With
In spleen eating less, having loose bowels just clear, fetal irritability.
Ligusticum wallichii：Nature and flavor：It is pungent, temperature.Channel tropism：Return liver, courage, pericardium channel.Effect：Blood-activating and qi-promoting, wind-expelling pain-stopping.Cure mainly：For
Irregular menstruation closed dysmenorrhea , Disorder lump in the abdomen is suffered from abdominal pain, chest side of body shouting pain, tumbling and swelling, headache.Arthralgia pain due to rheumatism.
Radix bupleuri：Nature and flavor：Hardship, is slightly cold.Channel tropism：Return liver, gallbladder channel.Effect：It is soothing the liver in inducing diaphoresis, rising Yang.Cure mainly：For feeling
Emit heating fevers and chills alternates, distending pain in the chest and hypochondrium, irregular menstruation；The prolapse of uterus, prolapse of the anus.
Safflower：Nature and flavor：It is pungent, temperature.Channel tropism：The thoughts of returning home, Liver Channel.Effect：Invigorate blood circulation, blood stasis removing analgesic.Cure mainly：For Amenorrhea,
Dysmenorrhoea, lochia , abdominal lump of mass in abdomen, injury from falling down, sore swell and ache curative.
Rhizoma cyperi：Nature and flavor：Pungent, slight bitter, micro-sweet, put down.Channel tropism：Return liver, spleen, tri-jiao channel.Effect：Promoting qi circulation and removing obstruction in the collateral, menstruction regulating and pain relieving.
Cure mainly：For stagnation of QI due to depression of the liver, chest, the side of body, abdominal distention, indigestion, chest gastral cavity ruffian, cold hernia stomachache, swollen breasts, menstruation is not
Adjust, closed dysmenorrhea.
Chinese medicine composition of the present invention meets the principle that traditional Chinese medicine debates disease treatment.The medicinal material of selection is divided into particle for oral administration and outer
It is inside and outside to treat simultaneously with application volatile oil, treat more comprehensive, rapider, lasting medicine is administered in affected area, belong to inside and outside simultaneous
Turn round and look at, the newborn addiction prescription treated both principal and secondary aspect of disease.The Chinese medicinal material of selection has promoting blood circulation and removing blood stasis, relaxes the muscles and stimulate the blood circulation, the effect of qi-regulating with, and makes
Valency is cheap, and the financial burden for also not resulting in patient is used for a long time, and is the ideal medicine of the newborn addiction for the treatment of.
Embodiment
Technical scheme is described in detail with reference to embodiment and experimental example, but protection domain is not limited by this.
A kind of Chinese medicine composition for treating newborn addiction of embodiment 1, takes the primary raw material of following weight proportions to be prepared from (often
Part takes 20g)：15 parts of Artemisia anomala, 20 parts of row night, 18 parts of latifolious rush rhizome, 10 parts of rascal, 9 parts of caulis clematidis armandii, 30 parts of the bighead atractylodes rhizome, 25 parts of Ligusticum wallichii,
9 parts of radix bupleuri, 6 parts of safflower, 15 parts of rhizoma cyperi.
The preparation method of above-mentioned Chinese medicine composition, step is：
(1) Artemisia anomala, latifolious rush rhizome, rascal and caulis clematidis armandii are dried 20 minutes slowly as low baking temperature on tile, taking-up dries in the air cool, with grinding
Alms bowl pulverization, crosses 130 mesh sieves；
(2) row night, radix bupleuri and rhizoma cyperi are placed in non iron container, add the vexed profit of light-coloured vinegar, the consumption of light-coloured vinegar is row night, bavin
Recklessly with 1 times of the total consumption of rhizoma cyperi；
(3) bulk drug obtained by step (2) is soaked 30 minutes, water consumption is 1 times, more than 80 DEG C of bulk drug weight
Water extraction 40 minutes, crosses 100 mesh screen packs, obtains decoction；
(4) by medicine liquid heating obtained by step (3) to seething with excitement, continue to filter after 1.5 hours, filtrate is concentrated into relative density and is
1.20, let cool；
(5) gained smalls in step (1) is added in filtrate obtained by step (4), dries, particle is made；
(6) bighead atractylodes rhizome, Ligusticum wallichii were smashed into 80 mesh sieves, plus 30 DEG C of warm water soaks 30 minutes, intense fire is fried open, and turns slow fire heating
Distillate is collected with distillation equipment or steam distillation is passed through 50 minutes, volatile oil is together distilled with water, collects distillation
Liquid, stands 30 minutes, distillate, which is cooled to after 40 DEG C, takes upper strata fluid, and safflower is added in fluid and is heated to 80 DEG C, is kept for 6 minutes
Sterilizing, is cooled to room temperature, after be distributed into air-tight bottle obtain external application application volatile oil.
Zou XX of model case one, female, 32 years old, Jinan City, Shandong Province personage, in December, 2012 morbidity, patient's readme：Usually go out
Existing mood is had some setbacks, and is hard and dry, the symptom such as breast fullness, touches with lump with hand, and caking distending pain is joined in charitable and pious deeds anger growth and decline, when spinosity
Bitterly, two side of body distending pain, always bitter taste of waking up morning goes to register the department of Chinese medicine, and doctor sees that its face is intense darkness without light, and pale tongue with thin fur is white, by pair
Patient is inquired, is diagnosed as newborn addiction, and because patient thinks expectant treatment, doctor's suggestion is taken and with the use of Chinese traditional medicine composition of the present invention
Thing.
Take and use cooperatively 1 resulting composition of embodiment after 5 days, malaise symptoms start to mitigate, after 2 courses for the treatment of patient from
Sense recovery from illness, consolidates 2 courses for the treatment of after recovery from illness, be discontinued so far without recurrence.
A kind of Chinese medicine composition for treating newborn addiction of embodiment 2, takes the primary raw material of following weight proportions to be prepared from (often
Part takes 10g)：30 parts of Artemisia anomala, 30 parts of row night, 25 parts of latifolious rush rhizome, 20 parts of rascal, 28 parts of caulis clematidis armandii, 40 parts of the bighead atractylodes rhizome, Ligusticum wallichii 40
Part, 18 parts of radix bupleuri, 14 parts of safflower, 28 parts of rhizoma cyperi.
The preparation method of above-mentioned Chinese medicine composition, step is：
(1) Artemisia anomala, latifolious rush rhizome, rascal and caulis clematidis armandii are dried 40 minutes slowly as low baking temperature on tile, taking-up dries in the air cool, with grinding
Alms bowl pulverization, crosses 130 mesh sieves；
(2) row night, radix bupleuri and rhizoma cyperi are placed in non iron container, add the vexed profit of light-coloured vinegar, the consumption of light-coloured vinegar is row night, bavin
Recklessly with 3 times of the total consumption of rhizoma cyperi；
(3) bulk drug obtained by step (2) is soaked 30 minutes, water consumption is 5 times, more than 80 DEG C of bulk drug weight
Water extraction 80 minutes, crosses 200 mesh screen packs, obtains decoction；
(4) by medicine liquid heating obtained by step (3) to seething with excitement, continue to filter after 1.5 hours, filtrate is concentrated into relative density and is
1.20, let cool；
(5) gained smalls in step (1) is added in filtrate obtained by step (4), dries, particle is made；
(6) bighead atractylodes rhizome, Ligusticum wallichii were smashed into 120 mesh sieves, plus 40 DEG C of warm water soaks 30 minutes, intense fire is fried open, and is turned slow fire and is added
Heat distillation equipment collects distillate or is passed through steam distillation 70 minutes, volatile oil is together distilled with water, collects and steams
Distillate, stands 30 minutes, distillate, which is cooled to after 40 DEG C, takes upper strata fluid, and safflower is added in fluid and is heated to 150 DEG C, 6 are kept
Minute sterilizing, is cooled to room temperature, after be distributed into air-tight bottle and obtain external application application volatile oil.
A kind of Chinese medicine composition for treating newborn addiction of embodiment 3, takes the primary raw material of following weight proportions to be prepared from (often
Part takes 20g)：23 parts of Artemisia anomala, 23 parts of row night, 20 parts of latifolious rush rhizome, 13 parts of rascal, 15 parts of caulis clematidis armandii, 33 parts of the bighead atractylodes rhizome, Ligusticum wallichii 30
Part, 13 parts of radix bupleuri, 9 parts of safflower, 23 parts of rhizoma cyperi.
The preparation method of above-mentioned Chinese medicine composition, step is：
(1) Artemisia anomala, latifolious rush rhizome, rascal and caulis clematidis armandii are dried 25 minutes slowly as low baking temperature on tile, taking-up dries in the air cool, with grinding
Alms bowl pulverization, crosses 135 mesh sieves；
(2) row night, radix bupleuri and rhizoma cyperi are placed in non iron container, add the vexed profit of light-coloured vinegar, the consumption of light-coloured vinegar is row night, bavin
Recklessly with 1.5 times of the total consumption of rhizoma cyperi；
(3) bulk drug obtained by step (2) is soaked 30 minutes, water consumption is 2 times, more than 80 DEG C of bulk drug weight
Water extraction 50 minutes, crosses 140 mesh screen packs, obtains decoction；
(4) by medicine liquid heating obtained by step (3) to seething with excitement, continue to filter after 1.5 hours, filtrate is concentrated into relative density and is
1.20, let cool；
(5) gained smalls in step (1) is added in filtrate obtained by step (4), dries, particle is made；
(6) bighead atractylodes rhizome, Ligusticum wallichii were smashed into 90 mesh sieves, plus 33 DEG C of warm water soaks 30 minutes, intense fire is fried open, and turns slow fire heating
Distillate is collected with distillation equipment or steam distillation is passed through 55 minutes, volatile oil is together distilled with water, collects distillation
Liquid, stands 30 minutes, distillate, which is cooled to after 40 DEG C, takes upper strata fluid, and safflower is added in fluid and is heated to 100 DEG C, is kept for 6 points
Clock sterilizing, is cooled to room temperature, after be distributed into air-tight bottle obtain external application application volatile oil.
A kind of Chinese medicine composition for treating newborn addiction of embodiment 4, takes the primary raw material of following weight proportions to be prepared from (often
Part takes 15g)：26 parts of Artemisia anomala, 28 parts of row night, 22 parts of latifolious rush rhizome, 18 parts of rascal, 18 parts of caulis clematidis armandii, 38 parts of the bighead atractylodes rhizome, Ligusticum wallichii 35
Part, 15 parts of radix bupleuri, 11 parts of safflower, 25 parts of rhizoma cyperi.
The preparation method of above-mentioned Chinese medicine composition, step is：
(1) Artemisia anomala, latifolious rush rhizome, rascal and caulis clematidis armandii are dried 35 minutes slowly as low baking temperature on tile, taking-up dries in the air cool, with grinding
Alms bowl pulverization, crosses 145 mesh sieves；
(2) row night, radix bupleuri and rhizoma cyperi are placed in non iron container, add the vexed profit of light-coloured vinegar, the consumption of light-coloured vinegar is row night, bavin
Recklessly with 2.5 times of the total consumption of rhizoma cyperi；
(3) bulk drug obtained by step (2) is soaked 30 minutes, water consumption is 4 times, more than 80 DEG C of bulk drug weight
Water extraction 70 minutes, crosses 180 mesh screen packs, obtains decoction；
(4) by medicine liquid heating obtained by step (3) to seething with excitement, continue to filter after 1.5 hours, filtrate is concentrated into relative density and is
1.20, let cool；
(5) gained smalls in step (1) is added in filtrate obtained by step (4), dries, particle is made；
(6) bighead atractylodes rhizome, Ligusticum wallichii were smashed into 110 mesh sieves, plus 38 DEG C of warm water soaks 30 minutes, intense fire is fried open, and is turned slow fire and is added
Heat distillation equipment collects distillate or is passed through steam distillation 65 minutes, volatile oil is together distilled with water, collects and steams
Distillate, stands 30 minutes, distillate, which is cooled to after 40 DEG C, takes upper strata fluid, and safflower is added in fluid and is heated to 130 DEG C, 6 are kept
Minute sterilizing, is cooled to room temperature, after be distributed into air-tight bottle and obtain external application application volatile oil.
The woods XX of model case two, female, 29 years old, Qingdao personage, in July, 2012 gave birth to a lovely baby, 2013
Year, September part gave child wean, and after weaning 1 month, patient feels breast secret anguish or shouting pain, fixed pain suddenly.Originally it is thought as
Baby's wean is just given, the milk that rises does not take notice of very much that shouting pain is increasingly severe after 2 months, and discovery lump is touched with hand premenstrual
Have a lump, and premenstrual lump increases, and reduces after and softens, with irregular menstruation, dysmenorrhoea etc. disease.Pink tongue tongue is white, and arteries and veins is thin
Moisten.The soreness of waist is weak, and few and color is light through water, household have purchased the Chinese medicine composition of the present invention of 3 courses for the treatment of to patient.
Take and use cooperatively 4 resulting composition of embodiment after 5 days, tingling sensation mitigates, and continues to take 1 course for the treatment of, patient
Self-induction is fully recovered, and 2 courses for the treatment of are taken without recurrence again after recovery from illness, and premenstrual lump disappears, and waist does not ache, also not dysmenorrhoea.
A kind of Chinese medicine composition for treating newborn addiction of embodiment 5, takes the primary raw material of following weight proportions to be prepared from (often
Part takes 30g)：24 parts of Artemisia anomala, 25 parts of row night, 21 parts of latifolious rush rhizome, 15 parts of rascal, 16 parts of caulis clematidis armandii, 35 parts of the bighead atractylodes rhizome, Ligusticum wallichii 33
Part, 14 parts of radix bupleuri, 10 parts of safflower, 24 parts of rhizoma cyperi.
(1) Artemisia anomala, latifolious rush rhizome, rascal and caulis clematidis armandii are dried 20-40 minutes slowly as low baking temperature on tile, taking-up dries in the air cool,
Mortar pulverization is used, 140 mesh sieves are crossed；
(2) row night, radix bupleuri and rhizoma cyperi are placed in non iron container, add the vexed profit of light-coloured vinegar, the consumption of light-coloured vinegar is row night, bavin
Recklessly with 2 times of the total consumption of rhizoma cyperi；
(3) bulk drug obtained by step (2) is soaked 30 minutes, water consumption is 3 times, more than 80 DEG C of bulk drug weight
Water extraction 60 minutes, crosses 160 mesh screen packs, obtains decoction；
(4) by medicine liquid heating obtained by step (3) to seething with excitement, continue to filter after 1.5 hours, filtrate is concentrated into relative density and is
1.20, let cool；
(5) gained smalls in step (1) is added in filtrate obtained by step (4), dries, particle is made；
(6) bighead atractylodes rhizome, Ligusticum wallichii were smashed into 100 mesh sieves, plus 35 DEG C of warm water soaks 30 minutes, intense fire is fried open, and is turned slow fire and is added
Heat distillation equipment collects distillate or is passed through steam distillation 60 minutes, volatile oil is together distilled with water, collects and steams
Distillate, stands 30 minutes, distillate, which is cooled to after 40 DEG C, takes upper strata fluid, and safflower is added in fluid and is heated to 120 DEG C, 6 are kept
Minute sterilizing, is cooled to room temperature, after be distributed into air-tight bottle and obtain external application application volatile oil.
The clinical practice of the Chinese medicine composition of the newborn addiction of the gained treatment of 1 embodiment of test example 5：200 are screened in 4 hospitals
Patient, oldest 45 years old, minimal ages 20 years old, average age 32 years old.1 week before experiment, the crowd is continuously seen
Examine, record symptom and change, be randomly divided into two groups, experimental group and control group, experimental group are taken the products obtained therefrom of embodiment 5, compareed
Group takes other medicines (conventional medication such as Ru Pi Ling", 'rupikang ' capsule).Application method is：Gained granule is 1 small after the meal three
When after take, take with warm water, each 3-5 grams, gained volatile oil is applied at mammary swelling, one is for several times, it is appropriate every time, 7
It is a course for the treatment of.Curative effect situation criterion：Cure：Take and using this product after, malaise symptoms have clear improvement, pain
It is basic to disappear；Effectively：Take and using this product after, malaise symptoms make moderate progress, and pain has mitigated；It is invalid：Take and use
After this product, malaise symptoms are unchanged.As a result as shown in table 1-2.
Table 1
Therapeutic effect：Take and using Chinese medicine composition effective percentage 98% of the present invention, 23% is higher by than control group.Effect is bright
It is aobvious to be better than control group.
Table 2：
Clinical tests prove that, take and using Chinese medicine composition of the present invention and the medicine phase for taking the newborn addiction of other treatment
Than, control that recurrence rate after healing is low, treatment means are more fully thorough, have no side effect during use, can be with while treatment newborn addiction
The symptoms such as pain, poor appetite, irregular menstruation, the endocrinopathy that alleviation is brought by newborn addiction.Clinical tests prove that, the present invention
Chinese medicine composition effective percentage 98%, most of newborn addiction patients were in medication 5 days or so, and pain symptom has obvious mitigation.In the present invention
Drug composition is a kind of medicine for safely and effectively treating newborn addiction.
Claims (18)
1. a kind of preparation method for the Chinese medicine composition for treating newborn addiction, it is characterised in that：The raw material of following weight proportions is taken to prepare
Form：15-30 parts of Artemisia anomala, night 20-30 parts of row, 18-25 parts of latifolious rush rhizome, 10-20 parts of rascal, 9-28 parts of caulis clematidis armandii, bighead atractylodes rhizome 30-
40 parts, 25-40 parts of Ligusticum wallichii, 9-18 parts of radix bupleuri, 6-14 parts of safflower, 15-28 parts of rhizoma cyperi；
Step is as follows：
(1) Artemisia anomala, latifolious rush rhizome, rascal and caulis clematidis armandii are dried 20-40 minutes slowly as low baking temperature on tile, taking-up dries in the air cool, with grinding
Alms bowl pulverization, crosses 130-150 mesh sieves；
(2) row night, radix bupleuri and rhizoma cyperi are placed in non iron container, add the vexed profit of light-coloured vinegar, the consumption of light-coloured vinegar be row night, radix bupleuri and
1-3 times of the total consumption of rhizoma cyperi；
(3) bulk drug obtained by step (2) is soaked 30 minutes, water consumption is 1-5 times of bulk drug weight, more than 80 DEG C water
Carry 40-80 minutes, cross 100-200 mesh screen packs, obtain decoction；
(4) by medicine liquid heating obtained by step (3) to seething with excitement, continue to filter after 1.5 hours, filtrate is concentrated into relative density and is
1.20, let cool；
(5) gained smalls in step (1) is added in filtrate obtained by step (4), dries, particle is made；
(6) bighead atractylodes rhizome, Ligusticum wallichii were smashed into 80-120 mesh sieves, plus 30-40 DEG C of warm water soaks 30 minutes, intense fire is fried open, and turns slow fire
Heating distillation equipment collects distillate or is passed through steam distillation 50-70 minutes, volatile oil is together distilled with water, receives
Collect distillate, stand 30 minutes, distillate, which is cooled to after 40 DEG C, takes upper strata fluid, safflower is added in fluid and is heated to 80 DEG C -150
DEG C, keep 6 minutes sterilizings, be cooled to room temperature, after be distributed into air-tight bottle obtain external application application volatile oil.
2. preparation method according to claim 1, it is characterised in that：Each raw material is as follows：23-26 parts of Artemisia anomala, row night 23-
28 parts, 20-22 parts of latifolious rush rhizome, 13-18 parts of rascal, 15-18 parts of caulis clematidis armandii, 33-38 parts of the bighead atractylodes rhizome, 30-35 parts of Ligusticum wallichii, radix bupleuri 13-
15 parts, 9-11 parts of safflower, 23-25 parts of rhizoma cyperi.
3. preparation method according to claim 1, it is characterised in that：Each raw material is as follows：24 parts of Artemisia anomala, 25 parts of row night,
21 parts of latifolious rush rhizome, 15 parts of rascal, 16 parts of caulis clematidis armandii, 35 parts of the bighead atractylodes rhizome, 33 parts of Ligusticum wallichii, 14 parts of radix bupleuri, 10 parts of safflower, 24 parts of rhizoma cyperi.
4. preparation method according to claim 1, it is characterised in that：Step (1) is by Artemisia anomala, latifolious rush rhizome, rascal and river
Akebi is dried 25-35 minutes slowly as low baking temperature on tile.
5. preparation method according to claim 4, it is characterised in that：Step (1) is by Artemisia anomala, latifolious rush rhizome, rascal and river
Akebi is dried 30 minutes slowly as low baking temperature on tile.
6. preparation method according to claim 1, it is characterised in that：Step (1) mortar pulverization, crosses 140 mesh sieves.
7. preparation method according to claim 1, it is characterised in that：The consumption of step (2) light-coloured vinegar is row night, radix bupleuri and perfume (or spice)
1.5-2.5 times of attached total consumption.
8. preparation method according to claim 7, it is characterised in that：The consumption of step (2) light-coloured vinegar is row night, radix bupleuri and perfume (or spice)
2 times of attached total consumption.
9. preparation method according to claim 1, it is characterised in that：Step (3) water consumption is the 2-4 of bulk drug weight
Times.
10. preparation method according to claim 9, it is characterised in that：Step (3) water consumption is 3 times of bulk drug weight.
11. preparation method according to claim 1, it is characterised in that：The water extraction 60 minutes of more than (3) 80 DEG C of step.
12. preparation method according to claim 1, scheme preferably is：Step (3) crosses 140-180 mesh screen packs.
13. preparation method according to claim 12, scheme preferably is：Step (3) crosses 160 mesh screen packs.
14. preparation method according to claim 1, it is characterised in that：The bighead atractylodes rhizome, Ligusticum wallichii were smashed 100 mesh by step (6)
Sieve.
15. preparation method according to claim 1, it is characterised in that：Step (6) is passed through steam distillation 55-65 minutes.
16. preparation method according to claim 15, it is characterised in that：Step (6) is passed through steam distillation 60 minutes.
17. preparation method according to claim 1, it is characterised in that：Safflower is added in step (6) fluid and is heated to 100-
130℃。
18. preparation method according to claim 17, it is characterised in that：Safflower is added in step (6) fluid and is heated to 120
℃。
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| 乳癖的辨证论治体会;郭萍;《中医函授通讯》;19970815;第16卷(第4期);第24页左栏第2段 * |
| 乳腺增生病中医治疗近况;黄海锋等;《湖南中医学院学报》;19960930;第16卷(第3期);第72-74页 * |
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