CN104435222A - Traditional Chinese medicinal preparation for preventing and treating ovine bluetongue - Google Patents

Traditional Chinese medicinal preparation for preventing and treating ovine bluetongue Download PDF

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Publication number
CN104435222A
CN104435222A CN201410747654.0A CN201410747654A CN104435222A CN 104435222 A CN104435222 A CN 104435222A CN 201410747654 A CN201410747654 A CN 201410747654A CN 104435222 A CN104435222 A CN 104435222A
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CN
China
Prior art keywords
preparation
radix
traditional chinese
ovine
bluetongue
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Pending
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CN201410747654.0A
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Chinese (zh)
Inventor
朱庆伟
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DENGFENG CITY LOVE ANIMAL HUSBANDRY DEVELOPMENT Co Ltd
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DENGFENG CITY LOVE ANIMAL HUSBANDRY DEVELOPMENT Co Ltd
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Priority to CN201410747654.0A priority Critical patent/CN104435222A/en
Publication of CN104435222A publication Critical patent/CN104435222A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/32Burseraceae (Frankincense family)
    • A61K36/324Boswellia, e.g. frankincense
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention discloses a traditional Chinese medicinal preparation for preventing and treating ovine bluetongue. The traditional Chinese medicinal preparation is prepared from the combination of the following raw medicinal materials: fructus forsythiae, astragalus membranaceus, radix paeoniae alba, frankincense, sanguisorba officinalis, radix sophorae flavescentis and solidago virgaurea. In order to achieve a better external application effect of preventing and treating the ovine bluetongue, the invention further provides a preparation of the traditional Chinese medicinal preparation; the preparation method comprises the following steps: step I) removing impurities from such raw medicinal materials as fructus forsythiae, astragalus membranaceus, radix paeoniae alba, frankincense, sanguisorba officinalis, radix sophorae flavescentis and solidago virgaurea, rapidly washing the medicinal materials by virtue of cold boiled water, and airing the medicinal materials; and step II) decocting the raw medicinal materials obtained in the step 1) with water above slow fire, so as to obtain the traditional Chinese medicinal preparation. The traditional Chinese medicinal preparation for preventing and treating ovine bluetongue disclosed by the invention is mainly applicable to the prevention and treatment of the ovine bluetongue through external application, capable of enhancing the immunity and disease resistance of sheep, and has functions of resisting bacteria and diminishing inflammation.

Description

The Chinese medicine preparation of control ovine blue tongue
Technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of Chinese medicine preparation preventing and treating ovine blue tongue; Mainly as external prevention and the treatment of ovine blue tongue, sheep autoimmunity and premunition can be strengthened, there is effect of anti-inflammation.
Background technology
Bluetongue is a kind of viral infectious of the ruminant taking insecticide as Vector of infection.Mainly betide sheep, its Clinical symptoms is heating, becomes thin, the ulcerative inflammation change of mouth, nose and gastric mucosa.Sheep susceptible, regardless of kind, sex and age, with the most susceptible of the sheep of about 1 years old, the lamb of sucking has certain resistance.The susceptibility of cattle and goat is lower, mostly is inapparent infection.Ill domestic animal is the source of infection of primary disease.Blood In Sheep of recovering can be with poison for 4 months, cattle, and these are with malicious animal to be also the source of infection.Primary disease transmits mainly through storehouse midge, and sheep hippoboscid (Melphagusovinus) also can mechanical inoculation primary disease.After bull infects, with virus in its seminal fluid, be transmitted to cow by copulation and artificial insemination.Virus is also by placental infection fetus.Sick has strict seasonality, the low laying areas more in damp and hot summer and early autumn, particularly pond, river of mostly occurring.Be mainly seen in oral cavity, cud, the heart, muscle, skin and hoof.There is rotten to the corn and dark red zone in oral cavity, tongue, gums, hard palate, cheek mucosa and lip edema.Cud has dark red zone, and there are vacuolar degeneration and necrosis in surface.Congested, the hemorrhage and edema of corium.Hemorrhage of muscle, myofibrosis, has serosity and gel-shaped to infiltrate sometimes between flesh.Respiratory tract, digestive tract and urinary tract mucosa and cardiac muscle, intracardiac adventitia all have point hemorrhage.Several cases, alimentary canal mucous membrane has necrosis and ulcer.The usual enlargement of spleen.Kidney and the slight inflammation of lymph node and edema, have laminitis to change sometimes.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine preparation preventing and treating ovine blue tongue; Mainly as external prevention and the treatment of ovine blue tongue, sheep autoimmunity and premunition can be strengthened, there is effect of anti-inflammation.
For achieving the above object, present invention employs following technical scheme: the present invention prevents and treats the Chinese medicine preparation of ovine blue tongue, it is characterized in that, combined by former material spice Fructus Forsythiae, the Radix Astragali, the Radix Paeoniae Alba, Olibanum, Radix Sanguisorbae, Radix Sophorae Flavescentis, Herba Solidaginis.
For reaching better prevention and the external effect for the treatment of ovine blue tongue, present invention also offers the preparation method of this Chinese medicine preparation;
Its preparation method is following steps: step one), by raw medicinal material Fructus Forsythiae, the Radix Astragali, the Radix Paeoniae Alba, Olibanum, Radix Sanguisorbae, Radix Sophorae Flavescentis, Herba Solidaginis remove impurity, eluriate rapidly with cold boiled water water, dry;
Step 2), step one) raw medicinal material that obtains and water slow fire decoct, and obtains Chinese medicine preparation.
Using method: obtained Chinese medicine preparation and water 3: 5 are fed rearing sheep in pens.
In the raw materials of traditional Chinese medicinal materials that the present invention chooses, its effect and pharmacological action respectively:
Herba Solidaginis: medical material nature and flavor: yellow skin gas delicate fragrance, property is put down, mildly bitter flavor, flat.Function cures mainly: wind and heat dispersing, anti-inflammation.For anemopyretic cold headache, (wind and cold is avoided) heat-clearing and toxic substances removing, detumescence is except pain.Upper respiratory tract infection, tonsillitis, laryngopharynx swelling and pain, bronchitis, pneumonia, pulmonary tuberculosis hemoptysis, acute and chronic nephritis, infantile malnutrition, traumatic injury is controlled in external, venom, sore swollen toxin, mastitis; Flavour of a drug return through: pungent, bitter, cool.Return lung, Liver Channel.
Radix Sophorae Flavescentis: the effect with anti-inflammation, all has inhibitory action to Propiobacterium, staphylococcus aureus, escherichia coli, can diuresis, antiallergic, ease pain, relieving asthma, eliminate the phlegm, [nature and flavor] bitter in the mouth; Cold in nature.[return through] liver; Kidney; Large intestine; Small intestine meridian; Bladder; Heart channel; Urinary bladder channel.[effect] 1, heat clearing and damp drying: extensive use and multiple humidifier fever, as damp-heat dysentery external can decoct soup washout, for hemorrhoid, women gynecological.Parasite killing (external), diuresis.
Radix Sanguisorbae: [meridian distribution of property and flavor] picric acid; Cold; Nontoxic.Return liver; Lung; Kidney; Large intestine channel.[effect] cooling blood for hemostasis, heat-clearing and toxic substances removing, detumescence sore.Spit blood, spitting of blood, epistaxis, hematuria, has blood in stool, hemorrhoidal bleeding, dysentery, metrorrhagia, leucorrhea with red and white discharge, sore, carbuncle and painful swelling, eczema, pudendal pruritus, burn due to hot liquid or fire, snake bite and insect sting.[pharmacological action] 1, astriction Radix Sanguisorbae contain tannin, have astriction, can antidiarrheal and hemostasis.2. antibacterial action; Experiment proves: the decocting liquid of Radix Sanguisorbae 100% all has inhibitory action in various degree to Bacillus typhi, meningococcus, shigella flexneri, bacterium sonnei, beta hemolytic streptococcus, staphylococcus aureus, Diplococcus pneumoniae, diphtheria corynebacterium, escherichia coli, bacillus subtilis, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, vibrio cholera and Bacillus tuberculosis.3. anastalsis; Radix Sangusorbae, water extract, charred Radix Sanguisorbae, Rhizoma sanguisorbae preparation all have blood effect processed.Radix Sanguisorbae water extract can make the bleeding time obviously shorten.
Olibanum: [meridian distribution of property and flavor] works hard, temperature.Enter the heart, liver, spleen channel.[pharmacological action] this product has more significant analgesic activity. and headed by Olibanum, the uterus ball of taste medicine antibacterially have stronger bacteriostasis than multiple, and effectively can kill infusorian. and regulating qi and activating blood, analgesic therapy, chases after poison.[effect] controls coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
The Radix Paeoniae Alba: chemical composition: paeoniflorin, paeonol, paeoniflorin, still containing benzoic acid, volatile oil, fatty oil, resin, tannin, sugar, starch, phlegmatic temperament, protein, cupreol and triterpenes etc.Property of medicine effect: the Radix Paeoniae Alba is cool in nature, bitter in the mouth acid, is slightly cold, has the effects such as blood-supplementing blood-nourishing, suppressing liver-YANG, easing the affected liver to relieve pain, astringing YIN to stop sweating, be applicable to fever due to yin deficiency, menoxenia, the breast abdomen pain over the hypochondriac region, extremity contraction suddenly, dysentery stomachache, spontaneous sweating, metrorrhagia, the inferior disease of band.Paeoniflorin has antibacterial, antipyretic, antiinflammatory, increase coronary flow, improves the effect of myocardial nutritional flow, blood vessel dilating, antagonism acute myocardial ischemia, anticoagulant, calmness, analgesia, spasmolytic, antiulcer, adjustment blood glucose.Radix Paeoniae Alba decoct can suppress dysentery bacterium, streptococcus pneumoniae, escherichia coli, Bacillus typhi, Hemolytic streptococcus, bacillus pyocyaneus etc.
The Radix Astragali: have 1, an exterior deficiency spontaneous perspiration, is used for the weak caused spontaneous perspiration of body void table.2, night sweat due to yin deficiency; 3, acute nephritis edema, for the void edema caused by YANG QI deficiency; 4, oedema due to chronic nephritis, spleen person who suffer from deficiency of kidney Yang; 5, yang-energy is weak, caves in, have and promote diabrosis and limitation effect for skin infection not diabrosis for a long time.6, skin infection is burst for a long time and is not healed, and after skin infection diabrosis, does not close up for a long time, has the effect of promoting tissue regeneration and wound healing; 7, syndrome of deficiency of spleen qi, weak asthenia, has loose bowels, sinking of QI of middle-JIAO, and internal organs prolapse, the indigestion and loss of appetite all diseases of lack of appetite.8, syndrome of deficiency of lung qi.With the passing of time, shortness of breath and tired spirit, expectorant harmony brings up in lung is unable cough with asthma.9, hyperhidrosis and edema.10, weak for the deficiency of vital energy, fatigue and weakness, or sinking of QI of middle-JIAO, proctoptosis, uterine prolapse.Nature and flavor: sweet, tepor.Gui Jing: return lung, spleen, liver, kidney channel; Have enhancing human body immunity function, protect the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Fructus Forsythiae: [chemical composition] fruit is containing forsythol, sterol compound, Saponin (without hemolytic) and Flavonoids, horse tongue resinol glycoside etc.Antibacterial action Fructus Forsythiae concentrated decotion has antibacterial action in vitro, can suppress Bacillus typhi, Salmonella paratyphi, escherichia coli, dysentery bacterium, diphtheria corynebacterium and vibrio cholera, staphylococcus, streptococcus etc.[function cures mainly] heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens, has the title of " persons particularly liable to develop skin infection's panacea ".Control warm, erysipelas, macule, carbuncle and ulcer toxic swelling, scrofula, urine stranguria with urinary obstruction, clearing away heart-fire.
The present invention prevents and treats the Chinese medicine preparation of ovine blue tongue; Mainly as external prevention and the treatment of ovine blue tongue, sheep autoimmunity and premunition can be strengthened, there is effect of anti-inflammation.
Detailed description of the invention
The present invention prevents and treats the Chinese medicine preparation of ovine blue tongue, it is characterized in that, is combined by former material spice Fructus Forsythiae, the Radix Astragali, the Radix Paeoniae Alba, Olibanum, Radix Sanguisorbae, Radix Sophorae Flavescentis, Herba Solidaginis.
For reaching better prevention and the external effect for the treatment of ovine blue tongue, present invention also offers the preparation method of this Chinese medicine preparation;
Its preparation method is following steps: step one), by raw medicinal material Fructus Forsythiae, the Radix Astragali, the Radix Paeoniae Alba, Olibanum, Radix Sanguisorbae, Radix Sophorae Flavescentis, Herba Solidaginis remove impurity, eluriate rapidly with cold boiled water water, dry;
Step 2), step one) raw medicinal material that obtains and water slow fire decoct, and obtains Chinese medicine preparation.
Using method: obtained Chinese medicine preparation and water 3: 5 are fed rearing sheep in pens.

Claims (1)

1. prevent and treat a Chinese medicine preparation for ovine blue tongue, it is characterized in that, combined by former material spice Fructus Forsythiae, the Radix Astragali, the Radix Paeoniae Alba, Olibanum, Radix Sanguisorbae, Radix Sophorae Flavescentis, Herba Solidaginis;
For reaching better prevention and the external effect for the treatment of ovine blue tongue, present invention also offers the preparation method of this Chinese medicine preparation;
Its preparation method is following steps: step one), by raw medicinal material Fructus Forsythiae, the Radix Astragali, the Radix Paeoniae Alba, Olibanum, Radix Sanguisorbae, Radix Sophorae Flavescentis, Herba Solidaginis remove impurity, eluriate rapidly with cold boiled water water, dry;
Step 2), step one) raw medicinal material that obtains and water slow fire decoct, and obtains Chinese medicine preparation.
CN201410747654.0A 2014-12-01 2014-12-01 Traditional Chinese medicinal preparation for preventing and treating ovine bluetongue Pending CN104435222A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104970240A (en) * 2015-06-29 2015-10-14 何以安 Feed additive for preventing and treating ovine bluetongue
CN105878832A (en) * 2016-04-19 2016-08-24 烟台民望机电技术有限公司 Traditional Chinese medicine composition for preventing and controlling sheep bluetongue and preparation method of traditional Chinese medicine composition

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1533784A (en) * 2003-04-02 2004-10-06 陈世杰 Chinese medicinal composition for treating animal virus zymosis
WO2007065883A1 (en) * 2005-12-06 2007-06-14 Istituto Di Ricerche Di Biologia Molecolare P.Angeletti S.P.A. Antiviral azanucleoside derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1533784A (en) * 2003-04-02 2004-10-06 陈世杰 Chinese medicinal composition for treating animal virus zymosis
WO2007065883A1 (en) * 2005-12-06 2007-06-14 Istituto Di Ricerche Di Biologia Molecolare P.Angeletti S.P.A. Antiviral azanucleoside derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104970240A (en) * 2015-06-29 2015-10-14 何以安 Feed additive for preventing and treating ovine bluetongue
CN105878832A (en) * 2016-04-19 2016-08-24 烟台民望机电技术有限公司 Traditional Chinese medicine composition for preventing and controlling sheep bluetongue and preparation method of traditional Chinese medicine composition

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Application publication date: 20150325