CN104432067A - Health food for relieving female climacteric syndrome - Google Patents
Health food for relieving female climacteric syndrome Download PDFInfo
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- CN104432067A CN104432067A CN201410801470.8A CN201410801470A CN104432067A CN 104432067 A CN104432067 A CN 104432067A CN 201410801470 A CN201410801470 A CN 201410801470A CN 104432067 A CN104432067 A CN 104432067A
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- health food
- auxiliary material
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- female dimacteric
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L21/00—Marmalades, jams, jellies or the like; Products from apiculture; Preparation or treatment thereof
- A23L21/20—Products from apiculture, e.g. royal jelly or pollen; Substitutes therefor
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Botany (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses a health food for relieving female climacteric syndrome. The health food is prepared from the following components in percentage by weight: 6-15% of bee milk lyophilized powder, 3-16% of rape pollen, 3-12% of a rhodiola rosea extract, 2-7% of coenzyme Q10, 1-5% of vitamins B and the balance of auxiliary materials. The health food is scientific and reasonable in composition, natural in component, appropriate in proportion, free of obvious side effects and convenient to take and can be used for effectively relieving female climacteric syndrome.
Description
Technical field
The present invention relates to the dietetic product changing food nutrition character, especially a kind of health food alleviating female dimacteric syndrome.
Background technology
Menopausal syndrome (MPS) refers to and to occur sex hormone fluctuation before and after postmenopausal women or a series of based on function disorder of autonomic nervous system caused by reducing, with one group of syndrome of neuropsychological symptom.The cardinal symptom of menopausal syndrome is the cardiovascular symptom because vegetative dystonia causes, mental symptom and dysbolism.As hypertension, flushed face, dizzy, tinnitus, dim eyesight, insomnia, failure of memory, anxiety, depression, neuroticism, emotional, emotional lability, pain of joint muscle, paramenia etc.
At present, the health food of the alleviation female dimacteric syndrome that market occurs is mainly with Chinese cassia tree, matrimony vine, the Radix Astragali, the traditional Chinese medicine ingredients such as motherwort are main, such as, application number be 201110192124.0 a kind of treat climacteric metancholia of women Chinese medicine and application number be 201310620633.8 a kind of health food alleviating female middle-aged climacteric metancholia, all have chosen the raw material of a lot of Chinese medicine or integration of drinking and medicinal herbs, by adjustment immunity of organisms, activate estrogen secretion level, scavenging free radicals, reach resisting oxidation and delaying senility, delay the effect of climacteric metancholia.But though integration of drinking and medicinal herbs Chinese medicine food has certain health-care effect, can not arbitrarily eat, targetedly and suitability, quantitative limitation be had, excessive edible or will not run counter to desire to the ill, easily have side effects.Therefore, develop a kind of safe and effective, and effect is comprehensively alleviated involutional health food and is just seemed particularly necessary.
Summary of the invention
There is the deficiency of side effect in order to the health food overcoming existing alleviation female dimacteric syndrome contains Chinese medicinal ingredients, the object of the present invention is to provide a kind of form scientific and reasonable, component is natural, proportioning is appropriate, the health food of the alleviation female dimacteric syndrome of effective, non-evident effect, taking convenience.
The technical solution adopted for the present invention to solve the technical problems is: a kind of health food alleviating female dimacteric syndrome, it is characterized in that: it is made up of the component of following weight percents: royal jelly freeze-dried powder 6 ~ 15%, rape pollen 3 ~ 16%, gadol extract 3 ~ 12%, ubiquinone
102 ~ 7%, B family vitamin 1 ~ 5%, all the other are auxiliary material, and the percentage by weight sum of each component is 100%.
Further, described auxiliary material is made up of starch, microcrystalline cellulose, dolomol, and wherein, the percentage by weight of described starch is 20 ~ 45%, and microcrystalline cellulose is 18 ~ 42%, and dolomol is 0.5 ~ 3%.
Precedence technique scheme of the present invention is: the percentage by weight of described each component is: royal jelly freeze-dried powder 12%, rape pollen 10%, gadol extract 10%, ubiquinone
103%, B family vitamin 3%, auxiliary material is 62%; Wherein, starch 30% in described auxiliary material, microcrystalline cellulose 30%, dolomol 2%.
The present invention makes tablet according to selecting auxiliary material to can be passed through the operations such as sieve, mixing, granulation, compressing tablet.Its concrete preparation technology belongs to prior art, repeats no more.
Usage of the present invention and consumption are: adult's recommended amounts every day is 1g.Be every day 2 times by human body recommended intake, each 1, can long-term taking.
Multiple natural extract selected by the health food of alleviation female dimacteric syndrome of the present invention, it is rich in the composition such as vitamin, amino acid, trace element that human body needs, wherein, each component effect is as follows: royal jelly freeze-dried powder contains more vitamin, especially B family vitamin is abundant especially, and containing the aliphatic acid of more than 26 kinds, can regulate and the metabolism of balanced human.In addition, also containing, for example glutamic acid, pantothenic acid, Cobastab
1, B
2, B
6, A, E etc. alleviate the natural components of climacteric metancholia; Royal jelly can regulate endocrine, internal system that is out of hand and balance is rejuvenated, skin can be made more to lubricate exquisiteness, pure white fitness, high resilience, minimizing wrinkle, postpone the aging of delaying skin; Rape pollen contains the functional materials comprising protein, vitamin, trace element, flavone compound, these materials act synergistically on body, balance endotrophic, strengthen metabolism, prevent the obstacle of capillary permeability, promote the growth of incretory, the disease that treatment and prevention are caused by endocrine dysfunction; Gadol extract is mainly containing phenyl propyl and flavonoid class, and its unique activity chemical composition is phenyl propyl, the symptom for climacteric obstacle: headache, Light-headedness, tired powerlessness, trick is ice-cold all can be improved; Rhodioside can make red blood cell band oxygen efficiency improve and increase CBF and speed, increases brain blood circulation, can produce psycholeptic effect, and not have the generation of sense of fatigue completely; Ubiquinone
10have improve body immunity, strengthen anti-oxidant, delay senility and strengthen the functions such as human activity
,ubiquinone
10be used alone or and Cobastab as a kind of powerful antioxidant
6(pyridoxol) is combined the modification that can suppress the microtubule system that acceptor is relevant to Cell Differentiation and activity on radical pair immunocyte, strengthens immune system, delays senility; B family vitamin comprises Cobastab
1, Cobastab
2, Cobastab
6, Cobastab
12, nicotinic acid, pantothenic acid, folic acid etc., be push body intracellular metabolite, indispensable material when sugar, fat, protein etc. are changed into heat, can stabilize nerve, anxiety of releiving, and sets the mind at rest, improves climacteric metancholia reaction.In the health food of alleviation female dimacteric syndrome of the present invention, have selected the natural components such as vitamin, protein, trace element, animals and plants extract, avoid the side effect that traditional Chinese medicine ingredients likely produces.Wherein, gadol extract can work in coordination with the hematopoiesis function strengthening royal jelly freeze-dried powder, stimulates circulation, and discharges vivotoxin; The level of B family vitamin adjustable body inner estrogen, adds that rape pollen and gadol extract nutrition content enrich, and higher containing flavonols, can strengthen vascular wall resistance simultaneously, reduce blood vessel permeability, have and reduce cholesterol and radiation-resistant effect.The present invention has adjustment female incretion, keeps the normal function of hormone secretion.Its composition is scientific and reasonable, component is natural, proportioning is appropriate, non-evident effect, taking convenience, effectively can alleviate female dimacteric syndrome.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Raw materials usedly in the present embodiment be commercial products, wherein,
Royal jelly freeze-dried powder purchased from Zhejiang woods master worker, wherein 10-hydroxyl-alpha-decylenic acid content >=5%; Its effect is: this royal jelly freeze-dried powder contains more vitamin, and especially B family vitamin is abundant especially, and containing the aliphatic acid of more than 26 kinds, can regulate and the metabolism of balanced human.In addition, also containing, for example glutamic acid, pantothenic acid, Cobastab
1, B
2, B
6, A, E etc. alleviate the natural components of climacteric metancholia; Royal jelly can regulate endocrine, and internal system that is out of hand and balance is rejuvenated.In addition, can also strong hemopoietic system, make red blood cell number showed increased in blood; Can also body's immunity be improved, there is very strong antiradiation ability.Skin can be made more to lubricate exquisiteness, pure white fitness, high resilience, minimizing wrinkle, postpone the aging of delaying skin.
Rape pollen is purchased from the bright source of Changge, its effect is: this rape pollen contains the functional materials comprising protein, vitamin, trace element, flavone compound, these materials act synergistically on body, balance endotrophic, strengthen metabolism, prevent the obstacle of capillary permeability, promote the growth of incretory, the disease that treatment and prevention are caused by endocrine dysfunction.
Gadol extract is purchased from sky, Hanzhong Rangu, and the content of its rhodioside is >=2%; Its effect is: this gadol extract is mainly containing phenyl propyl and flavonoid class, and its unique activity chemical composition is phenyl propyl, the symptom for climacteric obstacle: headache, Light-headedness, tired powerlessness, trick is ice-cold all can be improved.In addition, rhodiola root can improve rapidly the anoxic situation of human body brain and tissue, and its effect machine transfers to: improve oxygen content of blood, increases red blood cell and carries the efficiency of oxygen and improve blood flow and flow velocity, promote that trick is ice-cold, the symptom such as to have a dizzy spell.Rhodioside can make red blood cell band oxygen efficiency improve and increase CBF and speed, increases brain blood circulation, can produce psycholeptic effect, and not have the generation of sense of fatigue completely.
Ubiquinone
10purchased from newly with become, its content is>=99%.Its effect is: ubiquinone
10a kind of fat-soluble antioxidant, can the nutrition of human activin cell and cellular energy, have improve body immunity, strengthen anti-oxidant, delay senility and strengthen the functions such as human activity
,ubiquinone
10mainly contain two effects in vivo, one is be converted in the process of energy at nutriment to play an important role in mitochondria, and two is have obvious lipoid peroxidization resistant.The immunologic function decline increased with the age is the result of free radical and radical reaction, ubiquinone
10be used alone or and Cobastab as a kind of powerful antioxidant
6(pyridoxol) is combined the modification that can suppress the microtubule system that acceptor is relevant to Cell Differentiation and activity on radical pair immunocyte, strengthens immune system, delays senility.
B family vitamin comprises Cobastab
1, Cobastab
2, Cobastab
6, Cobastab
12, nicotinic acid, pantothenic acid, folic acid etc., be push body intracellular metabolite, indispensable material when sugar, fat, protein etc. are changed into heat.B family vitamin can stabilize nerve, anxiety of releiving, and sets the mind at rest, and improves climacteric metancholia reaction.
In the health food of alleviation female dimacteric syndrome of the present invention, gadol extract can work in coordination with the hematopoiesis function strengthening royal jelly freeze-dried powder, stimulates circulation, and discharges vivotoxin; The level of B family vitamin adjustable body inner estrogen, adds that rape pollen and gadol extract nutrition content enrich, and higher containing flavonols, can strengthen vascular wall resistance simultaneously, reduce blood vessel permeability, have and reduce cholesterol and radiation-resistant effect.The present invention has adjustment female incretion, keeps the normal function of hormone secretion.
embodiment 1
Alleviate a health food for female dimacteric syndrome, it is made up of the component of following weight percents: royal jelly freeze-dried powder 12%, rape pollen 10%, gadol extract 10%, ubiquinone
103%, B family vitamin 3%, auxiliary material is 62%; Wherein, starch 30% in described auxiliary material, microcrystalline cellulose 30%, dolomol 2%.The health food of the alleviation female dimacteric syndrome that the present embodiment provides, the adjustment female incretion had, keeps the normal function of hormone secretion.Its composition is scientific and reasonable, component is natural, proportioning is appropriate, non-evident effect, taking convenience, effectively can alleviate female dimacteric syndrome.
embodiment 2
Alleviate a health food for female dimacteric syndrome, it is made up of the component of following weight percents: royal jelly freeze-dried powder 15%, rape pollen 3%, gadol extract 12%, ubiquinone
106%, B family vitamin 1%, auxiliary material is 63%; Wherein, starch 20% in described auxiliary material, microcrystalline cellulose 42%, dolomol 1%.The health food of the alleviation female dimacteric syndrome that the present embodiment provides, its composition is scientific and reasonable, component is natural, non-evident effect, taking convenience, effectively can alleviate female dimacteric syndrome.
embodiment 3
Alleviate a health food for female dimacteric syndrome, it is made up of the component of following weight percents: royal jelly freeze-dried powder 6%, rape pollen 16%, gadol extract 3%, ubiquinone
107%, B family vitamin 2%, auxiliary material is 66%; Wherein, starch 45% in described auxiliary material, microcrystalline cellulose 18%, dolomol 3%.The health food of the alleviation female dimacteric syndrome that the present embodiment provides, its composition is scientific and reasonable, component is natural, non-evident effect, taking convenience, effectively can alleviate female dimacteric syndrome.
embodiment 4
Alleviate a health food for female dimacteric syndrome, it is made up of the component of following weight percents: royal jelly freeze-dried powder 10%, rape pollen 10%, gadol extract 10%, ubiquinone
102%, B family vitamin 5%, auxiliary material is 63%; Wherein, starch 27.5% in described auxiliary material, microcrystalline cellulose 35%, dolomol 0.5%.The health food of the alleviation female dimacteric syndrome that the present embodiment provides, its composition is scientific and reasonable, component is natural, non-evident effect, taking convenience, effectively can alleviate female dimacteric syndrome.
Finished product involved by the embodiment of the present invention 1 ~ 4, be according to given weight proportion component by pulverizing, sieve, mix, granulate, the normal process steps such as compressing tablet makes tablet.
carry out human experimentation with the given health food alleviating female dimacteric syndrome of embodiment 1 below, further illustrate the present invention and there is the effect alleviating female dimacteric syndrome.
1) person is tested
Menopausal syndrome patient 60 example, wherein age reckling 42 years old, the maximum 66 years old, 53.2 ± 6.7 years old mean age; Adopt Kupperman point system to mark, 27 routine symptoms are heavier, and 25 examples are light-duty menopausal syndrome patient, and before Kupperman scoring treatment, total score is total score 38.8 ± 7.3; Because there is premature ovarian failure symptom after hysterectomies on hysteromyoma in 8 examples.All patients all meet the diagnostic criteria of climacteric metancholia, without other chronic diseases, without using hormone contraindication, all do not use steroids drug therapy in nearly 3 months.All patients all carry out color ultrasound examination, understand uterus and ovary situation.The selected equal voluntary participation of all patients.
2) methods for the treatment of
Adopt Estrogen and progestin continuous sequential therapeutic scheme, namely patient's every day oral product 1g, 28d was 1 cycle, amounted to 3 cycles.And actively participate in the social activities of useful body and mind, keep good phychology, suitably participate in physical training, make it reach optimum therapeuticing effect.
3) Index for examination and efficacy determination
Clinical efficacy judges: by Kupperman scoring system in post-therapeutic evaluation menopausal syndrome coincident with severity degree of condition, and symptom score=basic point × degree scoring, every symptom score sum is total score.
Invalid: after treatment, integration comparatively treats front decline < 1/3;
Effective: after treatment, integration comparatively treats front decline > 1/3≤1/2;
Remarkable: after treatment, integration comparatively treats front decline > 1/2, each scoring 1 time before and after medication.
Empty stomach 12 hours before taking medicine, secondary blood drawing in morning measures serum estradiol (E2), follicle-stimulating hormone (FSH) (FSH), luteotropic hormone (LH), progestational hormone (P), alkaline phosphatase (AKP), T-CHOL (TC) and triglycerides (TG).These parameters is checked after treating 3 courses for the treatment of.
4) statistical procedures
Use SPSS13.0 to add up every data, analyze, parameters represents with means standard deviation (sx ±), checks with t, X2, and P < 0.05 has statistical significance for difference.
5) result
Effective 17 examples after the medication of three cycles, effective 40 examples, invalid 3 examples, total effective rate is 95%.After three cycle therapy, Kupperman clinical symptoms total scoring 11.6 ± 5.6, compares decline 97% with before medication, has remarkable statistical significance (P < 0.01).After HRT, every hormone of patient compares with before treatment with biochemical indicator, estradiol (E2), progestational hormone (P) obviously raise, and the indexs such as follicle-stimulating hormone (FSH) (FSH), luteotropic hormone (LH), alkaline phosphatase (AKP), T-CHOL (TC) and triglycerides (TG) all obviously reduce, and difference has statistical significance (P < 0.05).
Claims (3)
1. alleviate a health food for female dimacteric syndrome, it is characterized in that: it is made up of the component of following weight percents: royal jelly freeze-dried powder 6 ~ 15%, rape pollen 3 ~ 16%, gadol extract 3 ~ 12%, ubiquinone
102 ~ 7%, B family vitamin 1 ~ 5%, all the other are auxiliary material, and the percentage by weight sum of each component is 100%.
2. a kind of health food alleviating female dimacteric syndrome according to claim 1, it is characterized in that: described auxiliary material is made up of starch, microcrystalline cellulose, dolomol, wherein, the percentage by weight of described starch is 20 ~ 45%, microcrystalline cellulose is 18 ~ 42%, and dolomol is 0.5 ~ 3%.
3. alleviate the health food of female dimacteric syndrome according to claim 2 one kind, it is characterized in that: royal jelly freeze-dried powder 12%, rape pollen 10%, gadol extract 10%, ubiquinone
103%, B family vitamin 3%, auxiliary material is 62%; Wherein, starch 30% in described auxiliary material, microcrystalline cellulose 30%, dolomol 2%.
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