CN104428290B - 蒽基‑四内酰胺大环类及它们在检测靶糖中的用途 - Google Patents

蒽基‑四内酰胺大环类及它们在检测靶糖中的用途 Download PDF

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Publication number
CN104428290B
CN104428290B CN201380034334.4A CN201380034334A CN104428290B CN 104428290 B CN104428290 B CN 104428290B CN 201380034334 A CN201380034334 A CN 201380034334A CN 104428290 B CN104428290 B CN 104428290B
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compound
group
formula
groups
glucose
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Chinese (zh)
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CN104428290A (zh
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柯晨峰
A·P·戴维斯
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Ziylo Co Ltd
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University of Bristol
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/10—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CN201380034334.4A 2012-04-27 2013-04-26 蒽基‑四内酰胺大环类及它们在检测靶糖中的用途 Expired - Fee Related CN104428290B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1207392.0 2012-04-27
GBGB1207392.0A GB201207392D0 (en) 2012-04-27 2012-04-27 Novel compounds
PCT/GB2013/051079 WO2013160701A1 (en) 2012-04-27 2013-04-26 Anthracenyl - tetralactam macrocycles and their use in detecting a target saccharide

Publications (2)

Publication Number Publication Date
CN104428290A CN104428290A (zh) 2015-03-18
CN104428290B true CN104428290B (zh) 2017-11-14

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CN201380034334.4A Expired - Fee Related CN104428290B (zh) 2012-04-27 2013-04-26 蒽基‑四内酰胺大环类及它们在检测靶糖中的用途

Country Status (9)

Country Link
US (2) US9610365B2 (enExample)
EP (1) EP2855439B1 (enExample)
CN (1) CN104428290B (enExample)
AU (1) AU2013254450A1 (enExample)
CA (1) CA2910581A1 (enExample)
GB (2) GB201207392D0 (enExample)
HK (1) HK1209112A1 (enExample)
IN (1) IN2014DN09830A (enExample)
WO (1) WO2013160701A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201207392D0 (en) 2012-04-27 2012-06-13 Univ Bristol Novel compounds
WO2018167503A1 (en) * 2017-03-15 2018-09-20 Ziylo Limited Macrocyclic compounds
WO2020058322A1 (en) * 2018-09-19 2020-03-26 Ziylo Ltd. Glucose sensitive insulins and uses thereof
PL4003165T3 (pl) * 2019-07-30 2024-06-10 Emd Millipore Corporation Sposób syntezy związków chemicznych
RU2752711C2 (ru) * 2019-11-18 2021-07-30 Общество с ограниченной ответственностью «Лаборатория межклеточных технологий «Интерсел Рэнд» (ООО «Интерсел Рэнд») Способ и устройство для спектроскопии живой ткани
KR20230127067A (ko) * 2022-02-24 2023-08-31 삼성에스디아이 주식회사 코어-쉘 염료, 이를 포함하는 근적외선 흡수성 수지 조성물 및 근적외선 흡수 필름

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011059457A1 (en) * 2009-11-16 2011-05-19 University Of Notre Dame Du Lac High performance luminescent compounds
WO2011087521A1 (en) * 2010-01-13 2011-07-21 University Of Notre Dame Du Lac Chemiluminescent dyes and dye-stained particles

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6815901A (en) * 2000-06-02 2001-12-17 Zycos Inc Delivery systems for bioactive agents
JP2003073399A (ja) * 2001-08-31 2003-03-12 Japan Science & Technology Corp 発蛍光性修飾タンパク質
US7179616B1 (en) 2002-10-07 2007-02-20 University Of Notre Dame Du Lac Method for detecting phosphatidylserine on the surface of cells
US8642014B2 (en) * 2007-01-30 2014-02-04 Seta Biomedicals, Llc Luminescent compounds
GB201207392D0 (en) 2012-04-27 2012-06-13 Univ Bristol Novel compounds

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011059457A1 (en) * 2009-11-16 2011-05-19 University Of Notre Dame Du Lac High performance luminescent compounds
WO2011087521A1 (en) * 2010-01-13 2011-07-21 University Of Notre Dame Du Lac Chemiluminescent dyes and dye-stained particles

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
A Synthetic Lectin for β-Glucosyl;Nicholas P. Barwell，等;《Angew. Chem》;20090908;第121卷;第7809-7812页 *
Self-Assembly of Fluorescent Inclusion Complexes in Competitive Media Including the Interior of Living Cells;Jeremiah J. Gassensmith，等;《J. AM. CHEM. SOC.》;20071201;第129卷;第15054-15059页 *

Also Published As

Publication number Publication date
GB2517345A (en) 2015-02-18
US20150147275A1 (en) 2015-05-28
US9610365B2 (en) 2017-04-04
AU2013254450A1 (en) 2014-11-27
US9937272B2 (en) 2018-04-10
GB201420937D0 (en) 2015-01-07
GB201207392D0 (en) 2012-06-13
WO2013160701A1 (en) 2013-10-31
HK1209112A1 (en) 2016-03-24
CN104428290A (zh) 2015-03-18
IN2014DN09830A (enExample) 2015-08-07
EP2855439B1 (en) 2017-06-14
US20170266321A1 (en) 2017-09-21
CA2910581A1 (en) 2013-10-31
EP2855439A1 (en) 2015-04-08

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