CN104411326B - 抗哮喘的mtb‑c疫苗 - Google Patents

抗哮喘的mtb‑c疫苗 Download PDF

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Publication number
CN104411326B
CN104411326B CN201280071390.0A CN201280071390A CN104411326B CN 104411326 B CN104411326 B CN 104411326B CN 201280071390 A CN201280071390 A CN 201280071390A CN 104411326 B CN104411326 B CN 104411326B
Authority
CN
China
Prior art keywords
medicament
strain
mtb
mycobacterium tuberculosis
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201280071390.0A
Other languages
English (en)
Chinese (zh)
Other versions
CN104411326A (zh
Inventor
佩·雷琼·卡尔多纳·伊格莱西亚斯
伊莎贝尔·艾玛特·里拉
布兰卡·雷耶斯·莫雷诺
玛利亚·梅尔斯·艾玛特·法布瑞喀特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Archivel Farma SL
Original Assignee
Archivel Farma SL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Archivel Farma SL filed Critical Archivel Farma SL
Publication of CN104411326A publication Critical patent/CN104411326A/zh
Application granted granted Critical
Publication of CN104411326B publication Critical patent/CN104411326B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Dispersion Chemistry (AREA)
  • Transplantation (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201280071390.0A 2012-01-12 2012-01-12 抗哮喘的mtb‑c疫苗 Expired - Fee Related CN104411326B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IB2012/000353 WO2013104943A1 (en) 2012-01-12 2012-01-12 Mtb-c vaccine against asthma

Publications (2)

Publication Number Publication Date
CN104411326A CN104411326A (zh) 2015-03-11
CN104411326B true CN104411326B (zh) 2018-02-02

Family

ID=45852617

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280071390.0A Expired - Fee Related CN104411326B (zh) 2012-01-12 2012-01-12 抗哮喘的mtb‑c疫苗

Country Status (15)

Country Link
US (1) US9682042B2 (cg-RX-API-DMAC10.html)
EP (1) EP2802345B1 (cg-RX-API-DMAC10.html)
CN (1) CN104411326B (cg-RX-API-DMAC10.html)
AU (1) AU2012365465B2 (cg-RX-API-DMAC10.html)
BR (1) BR112014017217B1 (cg-RX-API-DMAC10.html)
CA (1) CA2861074C (cg-RX-API-DMAC10.html)
DK (1) DK2802345T3 (cg-RX-API-DMAC10.html)
ES (1) ES2670493T3 (cg-RX-API-DMAC10.html)
IN (1) IN2014MN01594A (cg-RX-API-DMAC10.html)
NO (1) NO2802345T3 (cg-RX-API-DMAC10.html)
PL (1) PL2802345T3 (cg-RX-API-DMAC10.html)
PT (1) PT2802345T (cg-RX-API-DMAC10.html)
RU (1) RU2602771C2 (cg-RX-API-DMAC10.html)
WO (1) WO2013104943A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA201405107B (cg-RX-API-DMAC10.html)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103720657B (zh) * 2013-11-19 2017-01-04 广东丸美生物技术股份有限公司 一种可变形脂质体的制备方法，及其制备的可变性脂质体
RU2652752C1 (ru) * 2017-06-15 2018-04-28 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт фундаментальной и клинической иммунологии" Способ лечения бронхиальной астмы
EP3797791A1 (en) * 2019-09-26 2021-03-31 Universidad De Zaragoza Therapeutic efficacy by pulmonary delivery of live attenuated mycobacteria

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102264389A (zh) * 2008-09-19 2011-11-30 阿尔西维尔法尔玛公司 适用于结核病初级预防的免疫治疗剂

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HUP9900378A3 (en) 1995-02-22 1999-11-29 Adcock Ingram Ltd A method for the isolation and purification of lipid cell-wall components
GB9813100D0 (en) 1998-06-18 1998-08-19 Secr Defence Method of forming liposomes
US20030022854A1 (en) 1998-06-25 2003-01-30 Dow Steven W. Vaccines using nucleic acid-lipid complexes
BR0103887C1 (pt) 2001-07-17 2005-11-08 Univ Minas Gerais Composições imunogênicas contendo microesferas biodegradáveis encapsulando antìgenos, vetores gênicos e adjuvantes
ES2231037B1 (es) 2003-10-31 2005-12-16 Archivel Technologies, Sl Agente inmunoterapico util para el tratamiento combinado de la tuberculosis en asociacion con otros farmacos.
EP1761662A4 (en) 2004-07-01 2010-02-03 Univ California PROTEOMICS WITH HIGH THROUGHPUT
PT2426141E (pt) 2005-04-29 2014-11-25 Glaxosmithkline Biolog Sa Método para prevenção ou tratamento de uma infecção por m. tuberculosis
WO2007022152A2 (en) 2005-08-15 2007-02-22 The Research Foundation Of State University Of New York Lipid nano particulates containing antigens as cancer vaccines
US9393215B2 (en) 2005-12-02 2016-07-19 Novartis Ag Nanoparticles for use in immunogenic compositions
TW200806317A (en) 2006-03-20 2008-02-01 Wyeth Corp Methods for reducing protein aggregation
US20090081284A1 (en) * 2006-04-20 2009-03-26 Tokai University Educational System Therapeutic agent for allergy containing liposome having oligosaccharide on its surface
HUE031951T2 (en) 2006-10-10 2017-08-28 Jina Pharmaceuticals Inc Aqueous systems for lipid-based drug compounds; preparations, processes and their use
ES2307402B1 (es) 2006-10-30 2009-09-30 Archivel Farma, S.L. Vacuna profilactica contra la tuberculosis.
CN101969976A (zh) 2008-01-11 2011-02-09 美国政府健康与人类服务部秘书处 针对分枝杆菌的多肽疫苗和接种策略
EP2421557B1 (en) 2009-04-24 2018-12-05 Statens Serum Institut A tuberculosis tb vaccine to prevent reactivation
SG190937A1 (en) 2010-12-14 2013-07-31 Glaxosmithkline Biolog Sa Mycobacterium antigenic composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102264389A (zh) * 2008-09-19 2011-11-30 阿尔西维尔法尔玛公司 适用于结核病初级预防的免疫治疗剂

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Effect of mycobacterium tuberculosis chaperonins on bronchial eosinophilia and hyper-responsiveness in a murine model of allergic inflammation;Riffo-vasquez Y et al.;《Clin exp allergy》;20040531;第34卷(第5期);712-719 *
New insights into the effects of mycobacterium bovis bacillus calmette-guerin on asthma;Zhang GS et al.;《Chin med j》;20090305;第122卷(第5期);577-583 *
The antiasthma effect of neonatal BCG vaccination does not depend on the Th17/IFN-I balance in a BALB/c mouse asthma model;Deng Y et al.;《J clin immunol》;20110222;第31卷(第3期);419-429 *

Also Published As

Publication number Publication date
CA2861074C (en) 2018-11-06
AU2012365465A1 (en) 2014-08-21
CA2861074A1 (en) 2013-07-18
EP2802345B1 (en) 2018-03-07
DK2802345T3 (en) 2018-04-30
ES2670493T3 (es) 2018-05-30
AU2012365465B2 (en) 2017-05-18
PL2802345T3 (pl) 2018-08-31
NO2802345T3 (cg-RX-API-DMAC10.html) 2018-08-04
US20150132364A1 (en) 2015-05-14
PT2802345T (pt) 2018-04-24
EP2802345A1 (en) 2014-11-19
WO2013104943A1 (en) 2013-07-18
ZA201405107B (en) 2020-11-25
RU2014133042A (ru) 2016-02-27
RU2602771C2 (ru) 2016-11-20
BR112014017217A8 (pt) 2017-07-04
BR112014017217B1 (pt) 2023-01-17
US9682042B2 (en) 2017-06-20
CN104411326A (zh) 2015-03-11
IN2014MN01594A (cg-RX-API-DMAC10.html) 2015-05-08
BR112014017217A2 (pt) 2017-06-13

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Granted publication date: 20180202

CF01 Termination of patent right due to non-payment of annual fee