CN104398625A - Traditional Chinese medication used for regulating and treating leucoderma - Google Patents
Traditional Chinese medication used for regulating and treating leucoderma Download PDFInfo
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- CN104398625A CN104398625A CN201410744974.0A CN201410744974A CN104398625A CN 104398625 A CN104398625 A CN 104398625A CN 201410744974 A CN201410744974 A CN 201410744974A CN 104398625 A CN104398625 A CN 104398625A
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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Abstract
The invention provides a traditional Chinese medication used for regulating and treating leucoderma, and belongs to the fields of traditional Chinese medicine and health care. The traditional Chinese medication is prepared from eight raw materials, namely rosa rugosa, semen persicae, zaocys dhumnades, cape jasmine fruits, liquorice, angelica dahurica, radix polygoni multiflori preparata and fructus mume praeparatus, effects of each medicine are coordinated, and all of the medicines work together to promote qi circulation, remove obstruction in the collateral, promote blood circulation, remove stasis, nourish liver and kidney, tonify qi, retain yin with astringency, clear heat, remove toxicity and balance pigments, so the aim of regulating and treating leucoderma is achieved. Clinical test data indicate that the traditional Chinese medication has an obvious function on regulation and treatment of leucoderma, and the total effective rate reaches 86%; additionally, the traditional Chinese medication uses medicinal and edible raw materials, has no toxicity or side effects and is an ideal health care product.
Description
Technical field
The present invention relates to a kind of for recuperating under medical treatment leukodermic Chinese medicine preparation, belonging to Chinese medicine health-care field.
Technical background
Vitiligo is a kind of common multiple pigmented dermatosis.This disease forms white macula for feature with local or general property depigmentation, is a kind of acquired limitation or general property depigmentation of skin, and be the common skin diseases of an impact beauty treatment, easily diagnose, treatment is difficult.Traditional Chinese medical science medical science is referred to as vitiligo, leucoderma.Vitiligo is the limitation white patch that posteriority occurs because of skin pigment depigmentation, makes local skin be white macula sample.Medically usually this pathological changes depigmentation.All groups, each position of whole body all can occur.Be common in and refer to the back of the body, wrist, forearm, face, neck and surrounding genital etc.Vitiligo often accompanies other autoimmune diseasees, as diabetes, thyroid disease, adrenal insufficiency, scleroderma, atoipc dermatitis, alopecia areata etc.
Leukodermic clinical manifestation is specifically divided into following three types: 1. topical type: (1) focal type: a place or many places white macula are confined to a region, but the not distribution in sections; (2) one-sided type (segmental pattern) a: place or many places white macula are sections distribution, suddenly disappear in midline; (3) mucosa type: only involve mucosa.2. be dispersed in type: (1) homeliness type: extensively and be dispersed in the white macula of distribution; (2) facial acra type: be distributed in face and extremity; (3) mixed type, segmental pattern: portion's acra type and/or homeliness type mixed distribution.3. general hair style: depigmentation all or almost all.According to investigations, the vitiligo of more than 90% is dispersed in type, and in remaining vitiligo, topical type is more than general hair style.
Current leukodermic Drug therapy mainly contains: (1) psoralen and derivant thereof; Rear irradiation ultraviolet radiation as oral in methoxsalen.(2) megavitamin: as vitamin B complex, vitamin C, Citrin long-term taking.(3) treatment such as medicine of useful cupric: as oral in 0.5% copper-bath.(4) immunomodulator: levamisole is oral, lyophilized bacillus calmette-guerin vaccine (BCG) intramuscular injection, oral Bovine Placenta etc.(5) skin irritant local is embrocated: skin is inflamed reaction, and impel pigment hypertrophy, dust head has 30% psoralea tincture, chlormethine ethanol, phenol (pure carbolic acid), 25%-50% trichloroacetic acid, Mylabris tincture etc.This method is only applicable to small pieces skin lesion, and after being coated with, skin lesion place can occur bulla.(6) corticosteroid hormone: various corticosteroid hormone is as local package treatments such as propanoic acid beclometasone ointment, halometasone cream, omcilon carbamide ointments.Not yet there is the leukodermic medicine of radical cure at present.
Summary of the invention
The object of this invention is to provide a kind of for recuperating under medical treatment leukodermic Chinese medicine preparation.
The traditional Chinese medical science is thought, many fighting in the not flourish skin of skin, disharmony between QI and blood, blood because of rheumatism of vitiligo forms, and has substantial connection with heredity, autoimmune etc.The present invention is according to investigating for many years, and vitiligo institute absolutely not overnight becomes, and is a kind of pathological changes that the long-term stasis of QI and blood shows on skin.The present invention is according to the leukodermic origin cause of formation, Flos Rosae Rugosae, Semen Persicae, Zaocys, Fructus Gardeniae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, Radix Polygoni Multiflori Preparata, Fructus Mume eight taste is selected to be that raw material carries out compatibility, effect of each medicine is produced collaborative, play the function of promoting QI circulation for relieving depression, blood circulation promoting and blood stasis dispelling, nourishing the liver and kidney, QI invigorating yin fluid astringing, heat-clearing and toxic substances removing, balance pigment altogether, to realize acting on leukodermic medical treatment.
Flos Rosae Rugosae, sweet, micro-hardship, temperature; Return liver, spleen channel; Function: promoting QI circulation for relieving depression, and blood, pain relieving.The present invention is monarch drug with Flos Rosae Rugosae, and vitiligo of the advocating stagnation of QI is the feature suffered from, for comprehensive improvement specifies leading direction.
Semen Persicae, sweet in the mouth, warm in nature; Return kidney, lung, large intestine channel; Function: the kidney invigorating, warming the lung, intestine moistening.Zaocys, sweet, flat; Return Liver Channel; Function: dispel the wind, dredging collateral, relieving convulsion.The present invention for ministerial drug, is devoted to blood circulation promoting and blood stasis dispelling with Semen Persicae, Zaocys, searches gas in fashion, resolving depression blood stasis dispelling, still to effect a permanent cure as core, lays foundation for administering vitiligo comprehensively.
Fructus Gardeniae, bitter, cold; GUIXIN, lung, tri-jiao channel; Function: pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Radix Glycyrrhizae, sweet, flat; GUIXIN, lung, spleen, stomach warp; Function: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.The present invention with Fructus Gardeniae, Radix Glycyrrhizae for adjuvant drug, from effect a permanent cure, the heat of clear three Jiao, the gas of poison, beneficial body in removing heat from blood.
The Radix Angelicae Dahuricae, pungent, temperature; Return stomach, large intestine, lung meridian; Function: loose wind dehumidifying, understand things pain-stopping, detumescence and apocenosis.Radix Polygoni Multiflori Preparata, bitter, sweet, puckery, tepor; Return liver, the heart, kidney channel; Function: invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening, changes turbid blood fat reducing.Fructus Mume is sour, puckery, flat; Return liver, spleen, lung, large intestine channel; Function: astringe the lung, astringing intestine to stop diarrhea, promotes the production of body fluid, relieving colic caused by ascaris.The present invention uses the leukodermic Radix Angelicae Dahuricae of traditional treatment, the Radix Polygoni Multiflori, Fructus Mume for making medicine, based on the table that takes stopgap measures, and immunity moderation, balance pigment.
Chinese medicine preparation of the present invention just plays the function of promoting QI circulation for relieving depression, blood circulation promoting and blood stasis dispelling, nourishing the liver and kidney, QI invigorating yin fluid astringing, heat-clearing and toxic substances removing, balance pigment entirely altogether, is ruled together by inside and outside, to realize acting on leukodermic medical treatment.The present invention adopts integration of edible and medicinal herbs raw material, no side effects, is a kind of desirable health promoting product.
In Chinese medicine preparation of the present invention, the weight proportion of each raw material: Flos Rosae Rugosae 25-38 part, Semen Persicae 14-22 part, Zaocys 14-22 part, Fructus Gardeniae 8-12 part, Radix Glycyrrhizae 8-12 part, Radix Angelicae Dahuricae 4-7 part, Radix Polygoni Multiflori Preparata 4-7 part, Fructus Mume 4-7 part.
Optimum ratio: Flos Rosae Rugosae 28-32 part, Semen Persicae 16-18 part, Zaocys 16-18 part, Fructus Gardeniae 8-10 part, Radix Glycyrrhizae 8-10 part, Radix Angelicae Dahuricae 5-6 part, Radix Polygoni Multiflori Preparata 5-6 part, Fructus Mume 5-6 part.
Optimum proportioning: Flos Rosae Rugosae 30 parts, 16 parts, Semen Persicae, Zaocys 16 parts, Fructus Gardeniae 10 parts, 10 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 6 parts, Radix Polygoni Multiflori Preparata 6 parts, Fructus Mume 6 parts.
Chinese medicine preparation of the present invention can be prepared into various oral preparations by the common process of pharmacy of Chinese materia medica and adjuvant.As capsule, tablet, granule, powder, pill (comprising the watered pill, honeyed pill, dragee, soft gelatin capsule, enteric coated pill or drop pill) or oral liquid.
Here is that Chinese medicine preparation of the present invention recuperates under medical treatment leukodermic clinical trial data.
1, the object of observation: be defined as being dispersed in type patients with vitiligo totally 50 examples through clinical diagnosis, the age 8-45 year between.
2, Therapeutic Method: granules medicine of the present invention (Semen Persicae polygonic multiflori tea): specification: 6g/ bag, 30 bags/box.Usage: each one bag sooner or later, warm water is directly taken after mixing it with water.The course for the treatment of: in the cycle in March 1, observed for 3 cycles.
3, curative effect judging standard: just take effect: the state of an illness starts to take a turn for the better, and white spot area reduces, and occurs stain (pigment island) in white macula.Obviously take effect: stain increases, merge in flakes, small pieces white macula disappears, and large stretch of white macula significantly reduces.Cure: white macula disappears completely, and white macula district skin can be slightly black in normal skin tone, recovering normal skin tone completely also must more than 3 month.
4, therapeutic effect: cure: 14 examples, account for 28%; Effective: 18 examples, account for 36%; Effective: 11 examples, account for 22%; Invalid: 7 examples, account for 14%.Total effective rate: 86%.
Detailed description of the invention
Below by specific embodiment, the proportioning raw materials of medicine of the present invention, preparation and usage are described further.
The preparation of embodiment 1, granules medicine
Composition of raw materials: Flos Rosae Rugosae 30 parts, 16 parts, Semen Persicae, Zaocys 16 parts, Fructus Gardeniae 10 parts, 10 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 6 parts, Radix Polygoni Multiflori Preparata 6 parts, Fructus Mume 6 parts;
Preparation technology: prepare the common process of granule by pharmaceutics and adjuvant is prepared from;
Specification: 6g/ bag;
Usage and dosage: each 6g sooner or later, warm water is directly taken after mixing it with water or is melted oral; 1 cycle of March, overview 3 cycle.The preparation of embodiment 2, capsule medicine
Composition of raw materials: Flos Rosae Rugosae 28 parts, 16 parts, Semen Persicae, Zaocys 16 parts, Fructus Gardeniae 8 parts, 8 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 5 parts, Radix Polygoni Multiflori Preparata 5 parts, Fructus Mume 5 parts;
Preparation technology: prepare the common process of capsule by pharmaceutics and adjuvant is prepared from;
Specification: every 0.3g;
Usage and dosage: each 0.9g sooner or later, warm water is directly taken after mixing it with water; 1 cycle of March, overview 3 cycle.
The preparation of embodiment 3, tablet medicine
Composition of raw materials: Flos Rosae Rugosae 32 parts, 18 parts, Semen Persicae, Zaocys 18 parts, Fructus Gardeniae 10 parts, 10 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 6 parts, Radix Polygoni Multiflori Preparata 6 parts, Fructus Mume 6 parts;
Preparation technology: prepare the common process of tablet by pharmaceutics and adjuvant is prepared from;
Specification: every sheet 1.0g;
Usage and dosage: each 3.0g sooner or later, warm water is directly taken after mixing it with water; 1 cycle of March, overview 3 cycle.
The preparation of embodiment 4, pill medicine
Composition of raw materials: Flos Rosae Rugosae 25 parts, 14 parts, Semen Persicae, Zaocys 14 parts, Fructus Gardeniae 8 parts, 8 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 4 parts, Radix Polygoni Multiflori Preparata 4 parts, Fructus Mume 4 parts;
Preparation technology: prepare the common process of pill by pharmaceutics and adjuvant is prepared from;
Specification: every 0.05g;
Usage and dosage: each 3.0g sooner or later, warm water is directly taken after mixing it with water; 1 cycle of March, overview 3 cycle.
The preparation of embodiment 5, oral liquid
Composition of raw materials: Flos Rosae Rugosae 38 parts, 22 parts, Semen Persicae, Zaocys 22 parts, Fructus Gardeniae 12 parts, 12 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 7 parts, Radix Polygoni Multiflori Preparata 7 parts, Fructus Mume 7 parts;
Preparation technology: prepare the common process of oral liquid by pharmaceutics and adjuvant is prepared from;
Specification: every bottle of 10ml;
Usage and dosage: each 20ml sooner or later, warm water is directly taken after mixing it with water; 1 cycle of March, overview 3 cycle.
In the various embodiments described above, each proportioning raw materials is all with parts by weight.
Claims (5)
1. for recuperating under medical treatment a leukodermic Health-protection traditional Chinese medicinal preparation, being with Flos Rosae Rugosae, Semen Persicae, Zaocys, Fructus Gardeniae, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, Radix Polygoni Multiflori Preparata, Fructus Mume for raw material, being prepared into various oral preparations by the common process of pharmacy of Chinese materia medica and adjuvant.
2. as claimed in claim 1 for recuperating under medical treatment leukodermic Health-protection traditional Chinese medicinal preparation, it is characterized in that: described each raw material carries out proportioning by following weight portion: Flos Rosae Rugosae 25-38 part, Semen Persicae 14-22 part, Zaocys 14-22 part, Fructus Gardeniae 8-12 part, Radix Glycyrrhizae 8-12 part, Radix Angelicae Dahuricae 4-7 part, Radix Polygoni Multiflori Preparata 4-7 part, Fructus Mume 4-7 part.
3. as claimed in claim 1 for recuperating under medical treatment leukodermic Health-protection traditional Chinese medicinal preparation, it is characterized in that: described each raw material carries out proportioning by following weight portion: Flos Rosae Rugosae 28-32 part, Semen Persicae 16-18 part, Zaocys 16-18 part, Fructus Gardeniae 8-10 part, Radix Glycyrrhizae 8-10 part, Radix Angelicae Dahuricae 5-6 part, Radix Polygoni Multiflori Preparata 5-6 part, Fructus Mume 5-6 part.
4. as claimed in claim 1 for recuperating under medical treatment leukodermic Health-protection traditional Chinese medicinal preparation, it is characterized in that: described each raw material carries out proportioning by following weight portion: Flos Rosae Rugosae 30 parts, 16 parts, Semen Persicae, Zaocys 16 parts, Fructus Gardeniae 10 parts, 10 parts, Radix Glycyrrhizae, the Radix Angelicae Dahuricae 6 parts, Radix Polygoni Multiflori Preparata 6 parts, Fructus Mume 6 parts.
5. as claimed in claim 1 for recuperating under medical treatment leukodermic Health-protection traditional Chinese medicinal preparation, it is characterized in that: described oral preparations is capsule, tablet, granule, medicinal tea, pill or oral liquid.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410744974.0A CN104398625A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medication used for regulating and treating leucoderma |
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| CN201410744974.0A CN104398625A (en) | 2014-12-09 | 2014-12-09 | Traditional Chinese medication used for regulating and treating leucoderma |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1491677A (en) * | 2002-10-25 | 2004-04-28 | 威 王 | Chinese medicine oral administration liquid for treating leukoderma |
| CN102397427A (en) * | 2010-09-07 | 2012-04-04 | 路世忠 | Sanwu angelica dahurica capsule both orally taken and externally applied in recuperating qi and blood and leucoderma |
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- 2014-12-09 CN CN201410744974.0A patent/CN104398625A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1491677A (en) * | 2002-10-25 | 2004-04-28 | 威 王 | Chinese medicine oral administration liquid for treating leukoderma |
| CN102397427A (en) * | 2010-09-07 | 2012-04-04 | 路世忠 | Sanwu angelica dahurica capsule both orally taken and externally applied in recuperating qi and blood and leucoderma |
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