CN101843705B - Chinese medicament for treating lupus erythematosus - Google Patents

Chinese medicament for treating lupus erythematosus Download PDF

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Publication number
CN101843705B
CN101843705B CN2009102355002A CN200910235500A CN101843705B CN 101843705 B CN101843705 B CN 101843705B CN 2009102355002 A CN2009102355002 A CN 2009102355002A CN 200910235500 A CN200910235500 A CN 200910235500A CN 101843705 B CN101843705 B CN 101843705B
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chinese medicine
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lupus erythematosus
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CN101843705A (en
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刘新壮
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Rugao Binjiang Urban Construction Investment Co Ltd
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Lvyuan Qiuzheng Technology Development Co Ltd
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Abstract

The invention relates to a Chinese medicament for treating lupus erythematosus, and belongs to the field of Chinese medicaments for treating dermatosis. The invention aims to provide the Chinese medicament with good effect and quick response. The Chinese medicament is prepared from the following raw materials: common clubmoss herb, root of rehmannia, Chinese angelica, cassia twig, processed radix aconiti, lucid ganoderma, radix pseudo-ginseng and the like. The Chinese medicament has the effects of tonifying qi and nourishing blood, activating blood and dissolving stasis, and dispelling wind and removing dampness, and has the advantages of obvious effect, exact medicinal effect and quick response.

Description

一种治疗红斑狼疮的中药A kind of traditional Chinese medicine for treating lupus erythematosus

技术领域technical field

本发明属于治疗皮肤病的中药领域。The invention belongs to the field of traditional Chinese medicine for treating skin diseases.

背景技术Background technique

目前,旨在治疗红斑狼疮的中药领域,存在着两个方面的不足:一是效果不够明显,二是见效比较迟缓。以致于许多红斑狼疮患者长期得不到有效药物的治疗,长期低热,皮肤损害和关节疼痛严重,并常常累及肾、心脏、呼吸系统等,病程迁延,反复发作,患者及其家属对此很不满意。At present, there are two deficiencies in the field of traditional Chinese medicine aimed at treating lupus erythematosus: one is that the effect is not obvious enough, and the other is that the effect is relatively slow. As a result, many patients with lupus erythematosus have not been treated with effective drugs for a long time. They have long-term low-grade fever, severe skin damage and joint pain, and often involve the kidneys, heart, and respiratory system. satisfy.

针对以上提出的问题,本发明提供一种治疗红斑狼疮的中药,它能解决以往此类中药治疗中效果不够明显,见效比较迟缓的问题,效果好、见效快,具有效果显著,药效确切,见效较快的优点。In view of the problems raised above, the present invention provides a traditional Chinese medicine for treating lupus erythematosus, which can solve the problem that the effect of this type of traditional Chinese medicine is not obvious enough and the effect is relatively slow in the past. The advantage of quicker results.

发明内容Contents of the invention

本发明是通过以下技术方案来实现的:The present invention is achieved through the following technical solutions:

1、一种治疗红斑狼疮的中药,采用中药原料制备,配方为(按重量比):1, a kind of Chinese medicine for the treatment of lupus erythematosus, adopts Chinese medicine raw material to prepare, and formula is (by weight):

伸筋草4-30份  生地4-30份      当归4-30份4-30 parts of Shenjincao 4-30 parts of Habitat 4-30 parts of Angelica

桂枝4-30份    制川乌3-25份    灵芝2-15份4-30 parts of Guizhi, 3-25 parts of Sichuan Aconitum, 2-15 parts of Lingzhi

三七3-25份Panax notoginseng 3-25 servings

这种治疗红斑狼疮的中药是由下列方法制成的:This traditional Chinese medicine for treating lupus erythematosus is made by the following methods:

(1)按上述重量比,将伸筋草、生地、当归、桂枝、制川乌经常规水提取工艺提取,制成浸膏细粉;(1) according to the above-mentioned weight ratio, the extracts of Herba Sinensis, Shengdi, Angelica, Guizhi, and Aconitum Aconitum are extracted through a conventional water extraction process to make extract powder;

(2)按上述重量比,将灵芝、三七分别研成细粉,与上述浸膏细粉混合,搅拌均匀;根据需要,可制成中药冲剂、颗粒剂、散剂、胶囊剂、水丸剂、片剂等剂型。(2) According to the above weight ratio, grind Ganoderma lucidum and Panax notoginseng into fine powder respectively, mix with the above-mentioned extract powder, and stir evenly; as required, it can be made into Chinese medicine granules, granules, powders, capsules, water pills, Dosage forms such as tablets.

本发明是根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。方中灵芝、生地扶正培本,益气养血,补益五脏;当归、三七活血化瘀;辅以桂枝温经通阳,善治风寒湿痹之酸痛及水肿、小便不利;伸筋草祛风除湿,舒筋活络,有退热、强心、利尿作用;制川乌祛风除湿,温经止痛,善治风寒湿痹,关节疼痛。诸药配伍,扶正祛邪,相得益彰,共奏益气养血,活血化瘀,祛风除湿之功,效果好,见效快,具有效果显著,药效确切,见效较快的优点。The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. In the prescription, Ganoderma lucidum and Shengdi Fuzheng Peiben can nourish qi and blood, and nourish the five internal organs; Angelica and Panax notoginseng promote blood circulation and remove blood stasis; supplemented with cassia twigs to warm the meridians and unblock yang, which is good for treating pain, edema, and dysuria caused by wind-cold-damp arthralgia; Shenjincao dispels wind and dampness , relax tendons and activate collaterals, have antipyretic, heart-strengthening, diuretic effects; make Chuanwu to dispel wind and dampness, warm meridians to relieve pain, and be good at treating wind-cold-damp arthralgia and joint pain. All the medicines are compatible, strengthen the body and eliminate pathogenic factors, complement each other, and play the functions of nourishing qi and nourishing blood, promoting blood circulation and removing blood stasis, expelling wind and dehumidification, with good effect and quick effect.

具体实施方式Detailed ways

通过以下实施方式对本发明做具体说明:The present invention is specifically described by the following embodiments:

1、取以下配方(重量按克为单位):1. Take the following formula (weight is in grams):

伸筋草60克  生地60克    当归60克60 grams of stretch grass, 60 grams of raw land, 60 grams of angelica

桂枝60克    制川乌50克  灵芝30克Guizhi 60g, Chuanwu 50g, Ganoderma lucidum 30g

三七60克Panax notoginseng 60g

按规定重量,用常规水提取工艺将伸筋草、生地、当归、桂枝、制川乌提取,制成浸膏细粉87克,将灵芝、三七分别研成细粉,与上述浸膏细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊632粒,每粒胶囊内含中药细粉及提取物0.28克。According to the specified weight, use the conventional water extraction process to extract Shenjincao, Shengdi, Angelica, Guizhi, and Aconitum Aconitum to make 87 grams of extract powder, and grind Ganoderma lucidum and Sanqi into fine powder respectively, and mix with the above extract The fine powder is mixed, stirred evenly, made into fine particles, packed into No. 0 capsules, and made into 632 Chinese medicine capsules, each capsule containing 0.28 grams of Chinese medicine fine powder and extract.

2、取以下配方(重量按克为单位):2. Take the following formula (weight is in grams):

伸筋草180克  生地180克    当归180克180 grams of stretch grass, 180 grams of raw land, 180 grams of angelica

桂枝180克    制川乌150克  灵芝90克Guizhi 180g, Chuanwu 150g, Ganoderma lucidum 90g

三七150克Panax notoginseng 150g

按上述同样的方法,制成中药胶囊1789粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 1789 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.

3、取以下配方(重量按克为单位):3. Take the following formula (the weight is in grams):

伸筋草300克  生地300克    当归300克300 grams of stretch grass, 300 grams of raw land, 300 grams of angelica

桂枝300克    制川乌250克  灵芝150克Guizhi 300g, Chuanwu 250g, Ganoderma lucidum 150g

三七250克Panax notoginseng 250g

按上述同样的方法,制成中药胶囊2982粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 2982 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.

4、取以下配方(按重量比):4. Take the following formula (by weight):

伸筋草7份  生地7份    当归7份7 parts of Shenjincao 7 parts of Habitat 7 parts of Angelica

桂枝7份    制川乌5份  灵芝4份7 parts of Guizhi, 5 parts of Sichuan Aconitum, 4 parts of Ganoderma lucidum

三七5份Panax notoginseng 5 copies

按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.

5、取以下配方(按重量比):5. Take the following formula (by weight):

伸筋草20份  生地20份    当归20份20 parts of Shenjincao 20 parts of Habitat 20 parts of Angelica

桂枝20份    制川乌16份  灵芝10份20 parts of Guizhi, 16 parts of Sichuan Aconitum, 10 parts of Ganoderma lucidum

三七16份Panax notoginseng 16 copies

按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.

临床资料:clinical information:

本发明以中医红斑狼疮为例,经12例临床观察。选择中医诊断红斑狼疮为标准:长期低热;皮损严重,面部和鼻梁呈蝴蝶状分布红斑;关节疼痛,周围组织肿胀;病情常累及肾脏、心脏、呼吸系统和消化系统。如上症状,即可确诊。在确诊观察的对象中,男性1例,女性11例,无其它严重疾病,年龄为25岁-45岁,平均年龄36.2岁。The present invention takes TCM lupus erythematosus as an example, through clinical observation of 12 cases. TCM diagnosis of lupus erythematosus was selected as the standard: long-term low-grade fever; severe skin lesions, butterfly-shaped erythema on the face and bridge of the nose; joint pain, swelling of surrounding tissues; the condition often involves the kidneys, heart, respiratory system and digestive system. The above symptoms can be diagnosed. Among the confirmed observation objects, there was 1 male and 11 females, without other serious diseases, aged from 25 to 45 years old, with an average age of 36.2 years.

疗效判定:Judgment of curative effect:

1、显效:低热消失,肢体有力;皮损明显缓解;关节疼痛减轻;肾脏、心脏、呼吸系统和消化系统病症缓解。1. Significant effect: low fever disappears, limbs are strong; skin lesions are obviously relieved; joint pain is relieved; kidney, heart, respiratory system and digestive system symptoms are relieved.

2、有效:低热、皮损、关节疼痛有所缓解。2. Effective: low fever, skin lesions, and joint pain are relieved.

3、无效:病症无变化。3. Ineffective: no change in symptoms.

临床实验时,停服其它药物和保健营养品。服用本发明中药胶囊,观察3个月,为一个疗程。服用方法:每日3次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.28克,饭后温开水送服,1个月后症状即有缓解,服用6个月后,症状明显改善。临床实验的12人中,显效6人,有效5人,无效1人,总有效率91.6%。During the clinical trial, stop taking other medicines and health nutrition products. Take Chinese medicine capsule of the present invention, observe 3 months, be a course of treatment. Dosing method: 3 times a day, 4 capsules each time, each capsule contains 0.28g of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 6 months of taking, Symptoms improved significantly. Among the 12 people in the clinical trial, 6 people were markedly effective, 5 people were effective, and 1 person was ineffective, and the total effective rate was 91.6%.

Claims (1)

1. a Chinese medicine for the treatment of lupus erythematosus is characterized in that, described Chinese medicine is to adopt the raw material of Chinese medicine preparation, and the weight proportion of raw material of Chinese medicine is:
Herba Lycopodii 4---30 parts in 30 parts of Radix Rehmanniae 4---30 parts of Radix Angelicae Sinensis 4---
Ramulus Cinnamomi 4---15 parts of 30 parts of Radix Aconiti Preparatas 3---25 portions of Ganodermas 2---
Radix Notoginseng 3---25 parts
The Chinese medicine of this treatment lupus erythematosus is made by following method:
(1) by above-mentioned weight ratio, Herba Lycopodii, the Radix Rehmanniae, Radix Angelicae Sinensis, Ramulus Cinnamomi, Radix Aconiti Preparata are extracted through conventional water extraction process, make the extractum fine powder;
(2) by above-mentioned weight ratio, Ganoderma, Radix Notoginseng are ground into fine powder respectively, mix, stir with above-mentioned extractum fine powder; Make Chinese medicine granules, capsule, watered pill, Tabules.
CN2009102355002A 2009-10-16 2009-10-16 Chinese medicament for treating lupus erythematosus Expired - Fee Related CN101843705B (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104547674A (en) * 2014-12-24 2015-04-29 广东聚智诚科技有限公司 New application of traditional Chinese medicinal composition

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1088788A (en) * 1992-12-26 1994-07-06 史宝印 A kind of lupus for the treatment of lupus erythematosus is loose and compound method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1088788A (en) * 1992-12-26 1994-07-06 史宝印 A kind of lupus for the treatment of lupus erythematosus is loose and compound method

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