CN104397529A - 一种参蓉茸多糖及其制备工艺 - Google Patents
一种参蓉茸多糖及其制备工艺 Download PDFInfo
- Publication number
- CN104397529A CN104397529A CN201410723653.2A CN201410723653A CN104397529A CN 104397529 A CN104397529 A CN 104397529A CN 201410723653 A CN201410723653 A CN 201410723653A CN 104397529 A CN104397529 A CN 104397529A
- Authority
- CN
- China
- Prior art keywords
- polysaccharide
- sea cucumber
- pilose antler
- preparation technology
- cistanche
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000004676 glycans Chemical class 0.000 title claims abstract description 48
- 229920001282 polysaccharide Polymers 0.000 title claims abstract description 48
- 239000005017 polysaccharide Substances 0.000 title claims abstract description 48
- 241000251511 Holothuroidea Species 0.000 title claims abstract description 17
- 210000003056 antler Anatomy 0.000 title claims abstract description 17
- 238000005516 engineering process Methods 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 241000005787 Cistanche Species 0.000 title abstract description 4
- 238000004519 manufacturing process Methods 0.000 claims abstract description 5
- 238000011049 filling Methods 0.000 claims abstract description 4
- 230000001954 sterilising effect Effects 0.000 claims abstract description 4
- 238000000227 grinding Methods 0.000 claims abstract description 3
- 238000000746 purification Methods 0.000 claims abstract description 3
- 241000209140 Triticum Species 0.000 claims description 11
- 235000021307 Triticum Nutrition 0.000 claims description 11
- 235000005911 diet Nutrition 0.000 claims description 11
- 230000037213 diet Effects 0.000 claims description 11
- 241000208340 Araliaceae Species 0.000 claims description 9
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 9
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 9
- 235000008434 ginseng Nutrition 0.000 claims description 9
- 239000007788 liquid Substances 0.000 claims description 6
- 241000233866 Fungi Species 0.000 claims description 5
- 238000000855 fermentation Methods 0.000 claims description 5
- 230000004151 fermentation Effects 0.000 claims description 5
- 235000015097 nutrients Nutrition 0.000 claims description 5
- 230000001580 bacterial effect Effects 0.000 claims description 4
- 239000002131 composite material Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 238000010298 pulverizing process Methods 0.000 claims description 2
- 238000004806 packaging method and process Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- 235000013402 health food Nutrition 0.000 abstract description 5
- 210000003734 kidney Anatomy 0.000 abstract description 5
- 210000000988 bone and bone Anatomy 0.000 abstract description 3
- 210000003205 muscle Anatomy 0.000 abstract description 3
- 208000007443 Neurasthenia Diseases 0.000 abstract description 2
- 206010003549 asthenia Diseases 0.000 abstract description 2
- 230000007812 deficiency Effects 0.000 abstract description 2
- 238000001914 filtration Methods 0.000 abstract description 2
- 238000005728 strengthening Methods 0.000 abstract description 2
- 241000336291 Cistanche deserticola Species 0.000 abstract 2
- 206010011878 Deafness Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 206010021928 Infertility female Diseases 0.000 abstract 1
- 208000037093 Menstruation Disturbances Diseases 0.000 abstract 1
- 206010027339 Menstruation irregular Diseases 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000013329 compounding Methods 0.000 abstract 1
- 231100000895 deafness Toxicity 0.000 abstract 1
- 208000016354 hearing loss disease Diseases 0.000 abstract 1
- 201000001881 impotence Diseases 0.000 abstract 1
- 201000005630 leukorrhea Diseases 0.000 abstract 1
- 201000008383 nephritis Diseases 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000004659 sterilization and disinfection Methods 0.000 abstract 1
- 206010046901 vaginal discharge Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 230000000975 bioactive effect Effects 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 238000010564 aerobic fermentation Methods 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000000840 anti-viral effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 229910052804 chromium Inorganic materials 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 150000002224 folic acids Chemical class 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 239000007943 implant Substances 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 238000011031 large-scale manufacturing process Methods 0.000 description 1
- 229910052748 manganese Inorganic materials 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 239000000575 pesticide Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 208000008128 pulmonary tuberculosis Diseases 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 235000018553 tannin Nutrition 0.000 description 1
- 229920001864 tannin Polymers 0.000 description 1
- 239000001648 tannin Substances 0.000 description 1
- -1 this quality Chemical class 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 150000003648 triterpenes Chemical class 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了参蓉茸多糖及其制备工艺，它由肉苁蓉多糖、鹿茸多糖、海参多糖组成，其重量百分比为：肉苁蓉多糖20-70％、鹿茸多糖10-60％、海参多糖10-50％。通过培养、过滤、提纯、干燥、粉碎、复配、灭菌、灌装制得。其属于有疗效作用的保健食品，适用于补肾助阳，强筋健骨、生津补髓。具有调节神经衰弱、肾炎、肾虚、耳聋目暗，阳痿遗精，虚寒带下，膀胱出血，高血压、贫血、女子不育，白带过多，月经不调，阴血不足等功效。
Description
技术领域：
本发明涉及一种补肾益精，补髓助阳，强筋健骨的保健食品，无毒副作用。尤其是一种真菌多糖深层发酵复配而成的保健食品及其制备工艺技术。
背景技术：
目前，由于人的生活环境逐年恶化，空气、水源和食物受到不同程度的污染，因此亚健康群体不断扩大，人体器官功能衰退甚至发生疾患。八大器官的功能调解，已经延伸至30岁以下的人群，而市场充斥的药物均存在不同程度的副作用，如二甲双胍等就存在肾损伤作用，也因为损伤而产生并发症。
发明内容：
本发明的目的在于克服上述不足，提供一种调整肝肾器官的新资源医疗保健食品，效果显著，切具有强筋壮骨，生精补髓，肺结核、神经衰弱，平定血压之功效，抗菌、抗病毒、抗氧化、护心养肝，补肾、抗衰老，调节免疫等。
本发明的目的是这样实现的：它由肉苁蓉多糖、鹿茸多糖、海参多糖组成，其重量百分比为：肉苁蓉多糖20-70％、鹿茸多糖10-60％、海参多糖10-50％。肉苁蓉多糖、鹿茸多糖、海参多糖的具体制备工艺分别是：菌种→斜面培养8-22天→摇瓶培养1-6天→发酵罐培养1-6天→过滤菌丝体，同时提炼培养液中的菌丝体→提纯多糖→干燥→粉碎→复配→灭菌→灌装→包装。培养温度-7-68℃，培养液PH值在4-7.8，粉碎粒度80-200目。
此参蓉茸多糖的生产属于好氧发酵，采用罐群体液体深层发酵技术。所述液体深层发酵技术就是，在装有无菌液体培养基的封闭式发酵罐中植入菌种，通过无菌空气并搅拌，进行发酵。其特点是：能够满足规模化生产，实现标准化、自动化，生产制备效率高，质量好，有效的避免了传统方法中的农药污染和重金属超标问题。
参蓉茸多糖对人体无毒无副作用，完全摒弃了沿袭千年的“是药三分毒”的传统授受。此因胞内多糖本身就是构成生命细胞的结构成分，而胞外多糖具有增强免疫而被业内专家称之为“糖被”的功能。
液体深层发酵技术生产出的参蓉茸多糖，其主要成分是真菌多糖、多氮，真菌多糖简称多糖。其含有其它生物活性成分有：氨基酸、糖蛋白、黄酮、三萜类、单宁、有机酸、本质素、叶酸衍生物、甾醇及微量元素Zn、Mg、Cu、Co、Mn、Cr、Fe、Mo等。这将大幅度缩小亚健康群体和中老年疾患受众。
依自然药材的生长条件和制备方式，尽管被称之为上药、上上药，其生物活性成分含量低，成药周期长，生产量不足，远不能满足过亿人口的医疗与保健需要，同样，肉苁蓉、鹿茸、海参及其它食药用菌也是如此。现在采用的液体深层发酵技术，就是在解决这些问题，此及人类福祉！
具体实施方式：
实施例一：
参蓉茸多糖是由肉苁蓉多糖、鹿茸多糖、海参多糖组成的保健食品，按重量百分比，肉苁蓉多糖20％、鹿茸多糖60％、海参多糖20％。
肉苁蓉多糖、鹿茸多糖、海参多糖的菌种经斜面培养、摇瓶培养、发酵罐培养、再经过滤、提纯、干燥、粉碎、复配、灭菌、灌装制得本产品。
实施例二：
与实施例一所不同的在于本发明的原料配比不同，按重量百分比，肉苁蓉多糖70％、鹿茸多糖20％、海参多糖10％。
实施例三：
与实施例一所不同的在于本发明的原料配比不同，按重量百分比，肉苁蓉多糖40％、鹿茸多糖10％、海参多糖50％。
Claims (4)
1.一种参蓉茸多糖及其制备工艺，其特征在于：它由肉苁蓉多糖、鹿茸多糖、海参多糖组成，其重量百分比为：肉苁蓉多糖20-70％、鹿茸多糖10-60％、海参多糖10-50％。
2.根据权利要求1所述的一种参蓉茸多糖及其制备工艺，其特征在于：真菌的液体深层发酵制作工艺，包括肉苁蓉多糖、鹿茸多糖、海参多糖，具体如下：菌种→斜面培养8-18天→摇瓶培养2-6天→发酵罐培养1-5天→过滤菌丝体，同时提炼培养液中的菌丝体→提纯多糖→干燥→粉碎→复配→灭菌→灌装→包装。
3.根据权利要求2所述的一种参蓉茸多糖及其制备工艺，其特征在于；培养温度-7-68℃，培养液PH值在4-7.8，粉碎粒度80-200目。
4.根据权利要求2所述的一种参蓉茸多糖及其制备工艺，其特征在于：多糖含量按重量比可超过80％。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410723653.2A CN104397529A (zh) | 2014-12-04 | 2014-12-04 | 一种参蓉茸多糖及其制备工艺 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410723653.2A CN104397529A (zh) | 2014-12-04 | 2014-12-04 | 一种参蓉茸多糖及其制备工艺 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104397529A true CN104397529A (zh) | 2015-03-11 |
Family
ID=52635251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410723653.2A Pending CN104397529A (zh) | 2014-12-04 | 2014-12-04 | 一种参蓉茸多糖及其制备工艺 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104397529A (zh) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1111989A (zh) * | 1993-11-13 | 1995-11-22 | 江西中医学院 | 抗衰老药品——肉苁蓉多糖的生产方法及制剂 |
| CN1403113A (zh) * | 2002-09-07 | 2003-03-19 | 辛耀禄 | 一种补肾活血生骨的药物及其制备方法 |
| WO2006053184A2 (en) * | 2004-11-10 | 2006-05-18 | The Trustees Of Columbia University In The City Of New York | Methods for treating or preventing a vascular disease |
| CN101698076A (zh) * | 2009-11-06 | 2010-04-28 | 蔡绪旺 | 一种补肾壮阳的中药制剂 |
| CN102382198A (zh) * | 2010-09-03 | 2012-03-21 | 威海中盛海洋生物科技有限公司 | 从海参加工液中提取海参粘多糖及制备速溶冻干粉的工艺 |
-
2014
- 2014-12-04 CN CN201410723653.2A patent/CN104397529A/zh active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1111989A (zh) * | 1993-11-13 | 1995-11-22 | 江西中医学院 | 抗衰老药品——肉苁蓉多糖的生产方法及制剂 |
| CN1403113A (zh) * | 2002-09-07 | 2003-03-19 | 辛耀禄 | 一种补肾活血生骨的药物及其制备方法 |
| WO2006053184A2 (en) * | 2004-11-10 | 2006-05-18 | The Trustees Of Columbia University In The City Of New York | Methods for treating or preventing a vascular disease |
| CN101698076A (zh) * | 2009-11-06 | 2010-04-28 | 蔡绪旺 | 一种补肾壮阳的中药制剂 |
| CN102382198A (zh) * | 2010-09-03 | 2012-03-21 | 威海中盛海洋生物科技有限公司 | 从海参加工液中提取海参粘多糖及制备速溶冻干粉的工艺 |
Non-Patent Citations (1)
| Title |
|---|
| 张传奇 等: "鹿茸多糖的研究概况", 《经济动物学报》 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105077029A (zh) | 富锌大麦苗晚餐代餐粉及其制备方法 | |
| CN106423355A (zh) | 一种梯次润麦工艺 | |
| CN102475031A (zh) | 一种由原生太岁制取养殖太岁的方法 | |
| CN103976203A (zh) | 一种美容养颜的果冻及其制备方法 | |
| CN102266001A (zh) | 冻干活性纳豆与藻类混合型干粉养生冲剂 | |
| CN109673899A (zh) | 一种醋蛋多肽饮料的制备方法 | |
| CN104521550A (zh) | 一种富硒灰树花栽培方法 | |
| CN105272443A (zh) | 生产富硒百色云耳用的培养基添加剂及其应用方法 | |
| CN103976202A (zh) | 一种可食用胶原蛋白果冻及其制备方法 | |
| CN106616105A (zh) | 一种黑枸杞保健饮品及其制备方法 | |
| CN106135689A (zh) | 一种利用冬虫夏草发酵废液生产的奶羊饲料添加剂 | |
| CN102813193A (zh) | 一种虫草花青口服液及其制备方法 | |
| KR20130026127A (ko) | 두피영양제조성물 및 그 제조방법 | |
| CN104855778A (zh) | 一种补肾滋阴多糖及其制备工艺 | |
| KR101114399B1 (ko) | 두피영양제조성물 및 그 제조방법 | |
| CN104397529A (zh) | 一种参蓉茸多糖及其制备工艺 | |
| KR102395146B1 (ko) | 농작물 성장촉진 비료제조방법 | |
| RU2550954C2 (ru) | Способ иммуномодуляции человека | |
| CN104522461A (zh) | 灵芝肽黄精多糖及其制备工艺 | |
| CN102161959A (zh) | 野生沙梨酒及其制作工艺 | |
| CN104366193A (zh) | 桦芝多糖及其制备工艺 | |
| CN104381790A (zh) | 菌三仙多糖及其制备工艺 | |
| CN111264723A (zh) | 一种提高虹鳟抗病性的饲料添加剂及制备方法和应用 | |
| CN104886710A (zh) | 一种调理肠胃功能的多糖矿泉水及其制备工艺 | |
| KR102404381B1 (ko) | 유효성분 강화 농산물 재배방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| CB03 | Change of inventor or designer information |
Inventor after: Li Zhicheng Inventor before: Li Zhicheng Inventor before: Liu Fuling Inventor before: Huang Yanhong Inventor before: Yang Fuguo Inventor before: Li Zhenming |
|
| COR | Change of bibliographic data | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160121 Address after: 063000, building 401, room 402, Eastern Mansion, No. 152, Jianshe North Road, Tangshan City hi tech Zone, Hebei, Applicant after: Tangshan Yu Yu Biotechnology Co., Ltd. Address before: 063000 C, Eastern Mansion, Tangshan City hi tech Development Zone, Hebei, 401 Applicant before: Li Zhicheng |
|
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150311 |
|
| WD01 | Invention patent application deemed withdrawn after publication |