CN104382035A - Double-layer horseradish buccal tablet for resisting respiratory tract allergy - Google Patents
Double-layer horseradish buccal tablet for resisting respiratory tract allergy Download PDFInfo
- Publication number
- CN104382035A CN104382035A CN201410735382.2A CN201410735382A CN104382035A CN 104382035 A CN104382035 A CN 104382035A CN 201410735382 A CN201410735382 A CN 201410735382A CN 104382035 A CN104382035 A CN 104382035A
- Authority
- CN
- China
- Prior art keywords
- horseradish
- powder
- buccal tablet
- double
- respiratory tract
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 240000003291 Armoracia rusticana Species 0.000 title claims abstract description 46
- 235000011330 Armoracia rusticana Nutrition 0.000 title claims abstract description 43
- 239000006189 buccal tablet Substances 0.000 title claims abstract description 22
- 229940046011 buccal tablet Drugs 0.000 title claims abstract description 19
- 210000002345 respiratory system Anatomy 0.000 title abstract description 7
- 206010020751 Hypersensitivity Diseases 0.000 title abstract description 6
- 208000026935 allergic disease Diseases 0.000 title abstract description 6
- 230000007815 allergy Effects 0.000 title abstract description 6
- 239000000843 powder Substances 0.000 claims abstract description 21
- 235000004298 Tamarindus indica Nutrition 0.000 claims abstract description 14
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 10
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 10
- 229940041616 menthol Drugs 0.000 claims abstract description 10
- 238000002360 preparation method Methods 0.000 claims abstract description 10
- 239000000463 material Substances 0.000 claims abstract description 8
- 241000596504 Tamarindus Species 0.000 claims description 12
- 208000028004 allergic respiratory disease Diseases 0.000 claims description 8
- 201000004335 respiratory allergy Diseases 0.000 claims description 8
- 238000005516 engineering process Methods 0.000 claims description 6
- 239000000796 flavoring agent Substances 0.000 claims description 5
- 235000019634 flavors Nutrition 0.000 claims description 5
- ZOJBYZNEUISWFT-UHFFFAOYSA-N allyl isothiocyanate Chemical compound C=CCN=C=S ZOJBYZNEUISWFT-UHFFFAOYSA-N 0.000 abstract description 16
- 230000000694 effects Effects 0.000 abstract description 13
- 210000000214 mouth Anatomy 0.000 abstract description 10
- 235000016720 allyl isothiocyanate Nutrition 0.000 abstract description 8
- 210000003296 saliva Anatomy 0.000 abstract description 6
- 102000004190 Enzymes Human genes 0.000 abstract description 5
- 108090000790 Enzymes Proteins 0.000 abstract description 5
- PHZOWSSBXJXFOR-UHFFFAOYSA-N 2-Propenyl glucosinolate Natural products OCC1OC(SC(CC=C)=NOS(O)(=O)=O)C(O)C(O)C1O PHZOWSSBXJXFOR-UHFFFAOYSA-N 0.000 abstract description 4
- 241000196324 Embryophyta Species 0.000 abstract description 4
- PHZOWSSBXJXFOR-MYMDCHNCSA-N Sinigrin Natural products S(=O)(=O)(O/N=C(\S[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@H](CO)O1)/CC=C)O PHZOWSSBXJXFOR-MYMDCHNCSA-N 0.000 abstract description 4
- 238000006911 enzymatic reaction Methods 0.000 abstract description 4
- QKFAFSGJTMHRRY-OCFLFPRFSA-M potassium;[(e)-1-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]sulfanylbut-3-enylideneamino] sulfate Chemical compound [K+].OC[C@H]1O[C@@H](S\C(CC=C)=N\OS([O-])(=O)=O)[C@H](O)[C@@H](O)[C@@H]1O QKFAFSGJTMHRRY-OCFLFPRFSA-M 0.000 abstract description 4
- 235000017291 sinigrin Nutrition 0.000 abstract description 4
- 230000001154 acute effect Effects 0.000 abstract description 3
- 238000004519 manufacturing process Methods 0.000 abstract description 3
- 238000000034 method Methods 0.000 abstract description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 3
- 210000002421 cell wall Anatomy 0.000 abstract description 2
- 235000013376 functional food Nutrition 0.000 abstract description 2
- 235000013402 health food Nutrition 0.000 abstract description 2
- 230000001737 promoting effect Effects 0.000 abstract description 2
- 230000028327 secretion Effects 0.000 abstract description 2
- 240000004584 Tamarindus indica Species 0.000 abstract 2
- 239000000203 mixture Substances 0.000 description 4
- 239000002994 raw material Substances 0.000 description 4
- 244000246386 Mentha pulegium Species 0.000 description 3
- 235000016257 Mentha pulegium Nutrition 0.000 description 3
- 235000004357 Mentha x piperita Nutrition 0.000 description 3
- 230000000172 allergic effect Effects 0.000 description 3
- 208000010668 atopic eczema Diseases 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 235000001050 hortel pimenta Nutrition 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 229940034610 toothpaste Drugs 0.000 description 3
- 239000000606 toothpaste Substances 0.000 description 3
- KKASGUHLXWAKEZ-UHFFFAOYSA-N 1-isothiocyanatopropane Chemical compound CCCN=C=S KKASGUHLXWAKEZ-UHFFFAOYSA-N 0.000 description 2
- 206010002198 Anaphylactic reaction Diseases 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000036783 anaphylactic response Effects 0.000 description 2
- 208000003455 anaphylaxis Diseases 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 229940112822 chewing gum Drugs 0.000 description 2
- 235000015218 chewing gum Nutrition 0.000 description 2
- 150000002540 isothiocyanates Chemical class 0.000 description 2
- 239000011812 mixed powder Substances 0.000 description 2
- 239000000668 oral spray Substances 0.000 description 2
- 229940041678 oral spray Drugs 0.000 description 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 2
- 230000000241 respiratory effect Effects 0.000 description 2
- 230000001954 sterilising effect Effects 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- -1 thiamines glucosides Chemical class 0.000 description 2
- 241000251468 Actinopterygii Species 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 239000004604 Blowing Agent Substances 0.000 description 1
- 244000180419 Brassica nigra Species 0.000 description 1
- 235000011291 Brassica nigra Nutrition 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 240000003945 Cochlearia officinalis Species 0.000 description 1
- 235000007463 Cochlearia officinalis Nutrition 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 244000178870 Lavandula angustifolia Species 0.000 description 1
- 235000010663 Lavandula angustifolia Nutrition 0.000 description 1
- 206010028748 Nasal obstruction Diseases 0.000 description 1
- 206010036790 Productive cough Diseases 0.000 description 1
- 208000036071 Rhinorrhea Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 239000005864 Sulphur Substances 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 244000195452 Wasabia japonica Species 0.000 description 1
- 235000000760 Wasabia japonica Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003266 anti-allergic effect Effects 0.000 description 1
- 230000002804 anti-anaphylactic effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229950005162 benexate Drugs 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 208000020670 canker sore Diseases 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000007071 enzymatic hydrolysis Effects 0.000 description 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
- 230000003628 erosive effect Effects 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 229930182470 glycoside Natural products 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000001900 immune effect Effects 0.000 description 1
- 230000007365 immunoregulation Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 125000004425 isosulfocyanate group Chemical group 0.000 description 1
- 239000001102 lavandula vera Substances 0.000 description 1
- 235000018219 lavender Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 229940105902 mint extract Drugs 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 244000045947 parasite Species 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 235000020374 simple syrup Nutrition 0.000 description 1
- 206010041232 sneezing Diseases 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 235000019614 sour taste Nutrition 0.000 description 1
- 235000013555 soy sauce Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000012289 standard assay Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 230000035900 sweating Effects 0.000 description 1
- 235000019605 sweet taste sensations Nutrition 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 235000019157 thiamine Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention discloses a double-layer horseradish buccal tablet for resisting respiratory tract allergy and belongs to the technical field of health foods or functional foods. The double-layer horseradish buccal tablet is composed of contents and a soluble shell for covering the contents; the contents are horseradish powder or horseradish powder and auxiliary materials required by a preparation process; the shell contains tamarind powder and menthol as well as the auxiliary materials required by the preparation process. The tamarind powder and the menthol have the effect of promoting salivary secretion; water in saliva provides a condition for an enzymatic reaction of the horseradish powder and involves in action of sinigrin and sinigrin enzyme; by the effects of the saliva of the oral cavity and the enzyme, the horseradish powder passes through plant cell walls and releases allyl isothiocyanate within a short time. Due to the temperature of 36 to 37 DEG C in the oral cavity, the enzymatic reaction process and the release of the allyl isothiocyanate are quickened, and the allyl isothiocyanate gets a relatively high concentration in the oral cavity within a short time, so that the allergy can be relieved in an acute stage of the respiratory tract allergy. The double-layer horseradish buccal tablet has a definite effect on the respiratory tract allergy and is goo in taste, low in production cost, convenient to carry and long in quality guarantee period.
Description
Technical field
The invention belongs to health food or technical field of functional food, be specifically related to a kind of buccal tablet of preventing respiratory allergy.Its symptom of said respiratory tract anaphylaxis comprises rhiocnesmus, sneezes, runny nose, nasal blockage, unsmooth breath etc.
Background technology
Horseradish (formal name used at school: Wasabia japonica) is spice crop, is that Cruciferae horseradish belongs to, and perennial root draft, the elongated nodular of underground rhizome, has petiole to come off vestige, have special aroma and pungent.The people such as China Li Cong adopt Wa Shabi Industrial Co., Ltd. of national standard assay Lijiang County In Yunnan Province city plant the main nutrient composition (see " Yunnan chemical " the 38th volume the 4th phase in 2011,17-18 page) of horseradish.Horseradish contains the various trace elements of abundant amino acid, vitamin and needed by human body.
After the tissue of this plant is destroyed, enzymatic hydrolysis is there is in the thiamines glucosides (also known as sinigrin) existed in its tissue under the effect of endogenous enzymes (also known as Sinigrinase), discharge the isosulfocyanate material of highly volatile, and produce unique pungent local flavor.The enzymolysis product allyl isothiocyanate of scurvy grass have sterilization, anti-oxidant, anticancer, eliminate parasite, improve a poor appetite, improve looks, the effect such as skin care.Horseradish powder is pulverized by the horseradish root of drying and is formed, and has commercial goods.
The patent No. is that the Chinese patent document of 200410040203.X discloses " a kind of medicine with immunoregulation effect ", is that to extract the oily mixture obtained be active drug composition to raw material with horseradish, and jointly forms this medicine with allowing the auxiliary element accepted.
Application number be 201310209517.7 Chinese patent document disclose " a kind of horseradish gum and preparation method thereof ", this chewing gum comprises the raw material of following weight portion: horseradish-Benexate Hydrochloride 2.4 ~ 3.6 parts, sugar alcohol 40 ~ 50 parts, matrix 30 ~ 40 parts.The object of this chewing gum is oral cavity cleaning, sterilization, anti-inflammatory.
Application number be 201310209226 Chinese patent document disclose a kind of horseradish oral spray and preparation method thereof, this oral spray is made up of the raw material of following percentage: horseradish extract 1% ~ 5%, solubilizer 5% ~ 10%, sorbefacient 0.1% ~ 0.5%, flavouring 0.02% ~ 0.08%, simple syrup 5% ~ 10% and 15% ~ ~ 35% ethanolic solution surplus.The object of this spray helps to eliminate canker sore position inflammation, and anti-bacteria is in the growth at curing ulcer erosion position.
Application number be 201310208516 Chinese patent document disclose a kind of horseradish toothpaste and preparation method thereof, this toothpaste is made up of the raw material of following mass percent: horseradish root mixed powder 50% ~ 60%, NMF 16% ~ 28%, binding agent 1.2% ~ 3.5%, blowing agent 1.0% ~ 3.0%, sweetener 0.2% ~ 0.5%, antioxidant 0.02% ~ 0.07% and deionized water surplus, described horseradish root mixed powder is that after freeze drying, (7 ~ 18) ︰ (32 ~ 50) low-temperature mixed pulverize obtained impalpable powder in mass ratio with rubbing agent by the root of horseradish plant.The object of this toothpaste is prevention decayed tooth, eliminates the harmful bacteria in oral cavity and remove halitosis, promotes gastrointestinal peristalsis and promotes appetite.
So far with horseradish be not also active ingredient, for the buccal tablet of preventing respiratory allergy.Although the functions such as the immunological regulation of horseradish are familiar with, horseradish to be made exact efficacy, the good price of mouthfeel can be accepted by consumer, easy to carry, long shelf-life, the irritated buccal tablet of practical preventing respiratory, be also a new problem, need to carry out more deep research and development.
Summary of the invention
The object of the present invention is to provide a kind of with horseradish be active ingredient, for the bilayered buccal tablets of preventing respiratory allergy.
The inventor of present patent application, on the basis of application study for many years, finds that horseradish has respiratory tract anti-allergic effects, and in dose-effect relationship, effectively can stop allergic symptom; The antianaphylactic dose-effect relationship of horseradish be edible test many times and allergic human population edible in the rule that finds, there is not yet forefathers' report.People eat raw fish be with the seasoned liquid of soy sauce or moisture content fully and horseradish powder stir, make the disintegration of horseradish plant tissue cell, hydrolysis generation glucose and allyl isothiocyanate under the effect of endogenous black mustard sulphur glycosides enzyme.
Product bilayered buccal tablets of the present invention is made up of content and the solvable shell that wraps up this content;
Said content is horseradish powder, or content is made up of auxiliary material required on horseradish powder and buccal tablet preparation technology;
Said solvable shell contains tamarind digested tankage and menthol, and the weight ratio of tamarind digested tankage and menthol is 1:0.08 ~ 0.12, is preferably 1:0.1, and containing auxiliary material required in buccal tablet preparation technology; Solvable shell can also containing required flavor enhancement;
The percentage by weight of content and solvable shell is 50 ~ 70%.
Said buccal tablet preparation technology and required auxiliary material thereof are routine techniques.
Tamarind another name tamarind, tamarind, local flavor is special, sweet and sour taste.Tamarind digested tankage is widely used in the middle of various flavouring at present, can increase the local flavor stereovision of food.The refrigerant sweating and heat resolving of peppermint.Food additives tamarind ready-mix powder, Herba Menthae powder and mint extract have commercially available prod.
Menthol system extracted by the leaf of peppermint and stem, and white crystal, molecular formula C10H20O is the main component in peppermint and lavender essential oil.
The mechanism of product of the present invention: the content horseradish powder of buccal tablet solvable shell parcel is long for storage period, and be also easy to carry use; But the isothiocyanates such as the propyl isorhodanide (propyl isothiocyanate) in horseradish powder must in the environment having water, and the cell membrane that could pass horseradish root discharges.Solvable shell not only mouthfeel is good, and can impel and salivate in a large number containing user oral cavity, thus allows the isothiocyanates such as the propyl isorhodanide (propyl isothiocyanate) in horseradish powder fully discharge to stimulate mouth and nose chamber, reaches the effect of preventing respiratory allergy.In other words, buccal tablet of the present invention a certain amount of tamarind digested tankage and menthol is wrapped in the horseradish powder of internal layer as solubility shell.Tamarind digested tankage and menthol have the effect promoting the production of body fluid and promote salivary secretion, make the short time in oral cavity produce a certain amount of saliva; In saliva of buccal cavity, moisture provides the condition of horseradish powder enzymatic reaction, and the moisture in saliva participates in sinigrin and Sinigrinase effect; Horseradish powder, under the effect of saliva of buccal cavity and enzyme, discharges allyl isothiocyanate through plant cell wall in the short period of time.In order to meet aforesaid dose-effect relationship, compared with normal room temperature, in human oral cavity, the temperature of 36-37 DEG C accelerates the release of this enzymatic reaction process and allyl isothiocyanate, and in the short time, allyl isothiocyanate reaches higher concentration in the oral cavity.Only quick effect can be reached in respiratory tract anaphylaxis acute stage, when allergy sufferers occur sneezing, have a running nose, drop tears, cough and expectoration time suck and take this horseradish bilayered buccal tablets, can reach only quick effect in a short time, the allergic symptom of acute stage is eased.
Beneficial effect of the present invention: the irritated exact efficacy of buccal tablet preventing respiratory, mouthfeel is good, and production cost is low, easy to carry, long shelf-life.
Detailed description of the invention
See following examples of series.
Claims (3)
1., for a double-deck horseradish buccal tablet for preventing respiratory allergy, it is characterized in that:
Be made up of content and the solvable shell that wraps up this content;
Described content is horseradish powder, or content is made up of auxiliary material required on horseradish powder and buccal tablet preparation technology;
Described solvable shell contains tamarind digested tankage and menthol, and the weight ratio of tamarind digested tankage and menthol is 1:0.08 ~ 0.12, and containing auxiliary material required in buccal tablet preparation technology;
The percentage by weight of content and solvable shell is 50 ~ 70%.
2., as claimed in claim 1 for the double-deck horseradish buccal tablet of preventing respiratory allergy, it is characterized in that: the weight ratio of tamarind digested tankage and menthol is 1:0.1.
3. as claimed in claim 1 for the double-deck horseradish buccal tablet of preventing respiratory allergy, it is characterized in that: solvable shell is also containing required flavor enhancement.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410735382.2A CN104382035B (en) | 2014-12-04 | 2014-12-04 | Double-deck horseradish buccal tablet for preventing respiratory allergy |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410735382.2A CN104382035B (en) | 2014-12-04 | 2014-12-04 | Double-deck horseradish buccal tablet for preventing respiratory allergy |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104382035A true CN104382035A (en) | 2015-03-04 |
CN104382035B CN104382035B (en) | 2017-10-10 |
Family
ID=52600083
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410735382.2A Active CN104382035B (en) | 2014-12-04 | 2014-12-04 | Double-deck horseradish buccal tablet for preventing respiratory allergy |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104382035B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106491419A (en) * | 2016-11-02 | 2017-03-15 | 四川蓝公府农业科技有限公司 | A kind of horseradish toothpaste and its production technology |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1593578A (en) * | 2004-07-13 | 2005-03-16 | 台青(四川)食品有限公司 | Immunity regulating medicine |
CN101237781A (en) * | 2005-05-19 | 2008-08-06 | 麦克内尔-Ppc股份有限公司 | Confectionery products for the treatment of dry mouth |
CN101427766A (en) * | 2007-11-07 | 2009-05-13 | 熊丽 | Balsam pear lozenge and producing process thereof |
CN103830599A (en) * | 2014-02-11 | 2014-06-04 | 毛庆云 | Anti-tooth decay buccal tablet and preparation method thereof |
-
2014
- 2014-12-04 CN CN201410735382.2A patent/CN104382035B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1593578A (en) * | 2004-07-13 | 2005-03-16 | 台青(四川)食品有限公司 | Immunity regulating medicine |
CN101237781A (en) * | 2005-05-19 | 2008-08-06 | 麦克内尔-Ppc股份有限公司 | Confectionery products for the treatment of dry mouth |
CN101427766A (en) * | 2007-11-07 | 2009-05-13 | 熊丽 | Balsam pear lozenge and producing process thereof |
CN103830599A (en) * | 2014-02-11 | 2014-06-04 | 毛庆云 | Anti-tooth decay buccal tablet and preparation method thereof |
Non-Patent Citations (1)
Title |
---|
亚瑟布朗斯坦博士: "《唤醒沉睡的自愈力》", 31 March 2014 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106491419A (en) * | 2016-11-02 | 2017-03-15 | 四川蓝公府农业科技有限公司 | A kind of horseradish toothpaste and its production technology |
Also Published As
Publication number | Publication date |
---|---|
CN104382035B (en) | 2017-10-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Sasi et al. | Garlic (Allium sativum L.) bioactives and its role in alleviating oral pathologies | |
CN104207982B (en) | Prevent Chinese medicine composition and the oral care product containing it that oral cavity is got angry | |
US20090155392A1 (en) | Methods and Systems for Sublingual Guarana Administration | |
CN112691057B (en) | Compound efficacy toothpaste and preparation method thereof | |
JP2003192605A (en) | Lipase inhibitant | |
CN108938501A (en) | Chinese medicine composition and oral care product applied to oral care product | |
CN109069453A (en) | For improving the composition and method that suffer from the hydration of individual of dysphagia | |
US9539296B2 (en) | Eye-refreshing agent to eliminate and alleviate eye fatigue and discomfort | |
CN105663014A (en) | Inflammation diminishing and whitening toothpaste containing rhizoma coptidis and fresh ginger | |
CN104382035B (en) | Double-deck horseradish buccal tablet for preventing respiratory allergy | |
CN109106671B (en) | Water bamboo moisturizing and anti-corrosion mask and preparation method thereof | |
Sandhu et al. | Caries protective foods: A futurist perspective | |
CN109464540A (en) | A kind of alleviation oral cavity and the spray of throat discomfort and preparation method thereof | |
CN109619248A (en) | Quickly eliminate bad breath the sugar-free hard candy piece and preparation method thereof for removing helicobacter pylori | |
JP2006109751A (en) | Functional chewable food, and method for producing the same | |
CN103191169B (en) | Olive processed by traditional Chinese medicines | |
JP2005281271A (en) | Skin moisturizing ability improving agent | |
CN109674713A (en) | A kind of preparation method of essence that alleviating canker sore and composition for oral cavity containing the essence | |
KR101078765B1 (en) | Edible composition for prevention of periodontal disease by growth of bacteria in the mouth | |
CN106511759B (en) | A kind of composition and its preparation method and application | |
JP2015166328A (en) | Chewable tablet | |
CN108635283A (en) | Bacteria inhibiting composition, antibacterial toothpaste and preparation method thereof | |
CN109730312A (en) | Enzyme composition and its application | |
CN109846794A (en) | A kind of composition, microballoon comprising the composition and preparation method thereof | |
CN111956741B (en) | A plant composition for promoting salivary secretion and relieving xerostomia, and its preparation method |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20221102 Address after: 650500 Zone B, Floor 2, Workshop 4, No. 51 Hongxiang Road, Singapore Industrial Park, Xiaoxince Community, Luoyang Sub district Office, Economic Development Zone, Kunming, China (Yunnan) Pilot Free Trade Zone Patentee after: Yunnan Gaoye Coffee Co.,Ltd. Address before: Room 602, Unit 2, Building 5, Xichang Garden, No. 11 Ankang Road, Xishan District, Kunming, Yunnan 650000 Patentee before: Li Nan |
|
TR01 | Transfer of patent right |