CN104366508A - Lutein ester or lutein emulsion and preparation method of lutein ester or lutein emulsion - Google Patents
Lutein ester or lutein emulsion and preparation method of lutein ester or lutein emulsion Download PDFInfo
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- CN104366508A CN104366508A CN201410637502.5A CN201410637502A CN104366508A CN 104366508 A CN104366508 A CN 104366508A CN 201410637502 A CN201410637502 A CN 201410637502A CN 104366508 A CN104366508 A CN 104366508A
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- lutein
- emulsifying agent
- lutein ester
- emulsion
- ester
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- KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 title claims abstract description 113
- 239000000839 emulsion Substances 0.000 title claims abstract description 46
- 229960005375 lutein Drugs 0.000 title claims abstract description 37
- KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 title claims abstract description 37
- FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 title claims abstract description 37
- 235000012680 lutein Nutrition 0.000 title claims abstract description 35
- 239000001656 lutein Substances 0.000 title claims abstract description 35
- ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 title claims abstract description 35
- 238000002360 preparation method Methods 0.000 title abstract description 21
- 238000004945 emulsification Methods 0.000 title description 5
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 46
- 239000002904 solvent Substances 0.000 claims abstract description 27
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 24
- 230000036541 health Effects 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims abstract description 8
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 38
- 239000003921 oil Substances 0.000 claims description 27
- 235000019198 oils Nutrition 0.000 claims description 27
- -1 sucrose fatty ester Chemical class 0.000 claims description 20
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 19
- 229930003427 Vitamin E Natural products 0.000 claims description 19
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 19
- 239000011709 vitamin E Substances 0.000 claims description 19
- 235000019165 vitamin E Nutrition 0.000 claims description 19
- 229940046009 vitamin E Drugs 0.000 claims description 19
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 14
- 239000007788 liquid Substances 0.000 claims description 14
- 239000013078 crystal Substances 0.000 claims description 13
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 12
- 229930195729 fatty acid Natural products 0.000 claims description 12
- 239000000194 fatty acid Substances 0.000 claims description 12
- 238000003756 stirring Methods 0.000 claims description 12
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 10
- 239000008158 vegetable oil Substances 0.000 claims description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 9
- 235000011187 glycerol Nutrition 0.000 claims description 8
- 239000002245 particle Substances 0.000 claims description 7
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims description 6
- 235000013305 food Nutrition 0.000 claims description 6
- 229920000223 polyglycerol Polymers 0.000 claims description 6
- ARIWANIATODDMH-UHFFFAOYSA-N rac-1-monolauroylglycerol Chemical compound CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 claims description 6
- JLPULHDHAOZNQI-ZTIMHPMXSA-N 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCC\C=C/C\C=C/CCCCC JLPULHDHAOZNQI-ZTIMHPMXSA-N 0.000 claims description 5
- 235000004347 Perilla Nutrition 0.000 claims description 5
- 229930006000 Sucrose Natural products 0.000 claims description 5
- 229940083466 soybean lecithin Drugs 0.000 claims description 5
- 239000005720 sucrose Substances 0.000 claims description 5
- 239000000944 linseed oil Substances 0.000 claims description 4
- 235000021388 linseed oil Nutrition 0.000 claims description 4
- 238000002156 mixing Methods 0.000 claims description 4
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 4
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
- 239000002202 Polyethylene glycol Substances 0.000 claims description 3
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims description 3
- 229940068939 glyceryl monolaurate Drugs 0.000 claims description 3
- 238000005304 joining Methods 0.000 claims description 3
- 239000000787 lecithin Substances 0.000 claims description 3
- 235000010445 lecithin Nutrition 0.000 claims description 3
- 229940067606 lecithin Drugs 0.000 claims description 3
- 239000000845 maltitol Substances 0.000 claims description 3
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims description 3
- 235000010449 maltitol Nutrition 0.000 claims description 3
- 229940035436 maltitol Drugs 0.000 claims description 3
- WWZKQHOCKIZLMA-UHFFFAOYSA-M octanoate Chemical class CCCCCCCC([O-])=O WWZKQHOCKIZLMA-UHFFFAOYSA-M 0.000 claims description 3
- 229920001223 polyethylene glycol Polymers 0.000 claims description 3
- 238000006116 polymerization reaction Methods 0.000 claims description 3
- 229920000136 polysorbate Polymers 0.000 claims description 3
- 238000005829 trimerization reaction Methods 0.000 claims description 3
- 244000124853 Perilla frutescens Species 0.000 claims 1
- 238000005516 engineering process Methods 0.000 abstract description 6
- 238000005265 energy consumption Methods 0.000 abstract description 4
- 230000009286 beneficial effect Effects 0.000 abstract description 3
- 239000003814 drug Substances 0.000 abstract description 3
- 150000001413 amino acids Chemical class 0.000 abstract description 2
- 239000002537 cosmetic Substances 0.000 abstract description 2
- 235000020510 functional beverage Nutrition 0.000 abstract description 2
- 239000006041 probiotic Substances 0.000 abstract description 2
- 235000018291 probiotics Nutrition 0.000 abstract description 2
- 229940079593 drug Drugs 0.000 abstract 1
- 238000009776 industrial production Methods 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 description 12
- 239000000203 mixture Substances 0.000 description 11
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 6
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 4
- 241000229722 Perilla <angiosperm> Species 0.000 description 4
- 238000013019 agitation Methods 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
- 150000002148 esters Chemical class 0.000 description 4
- 230000004438 eyesight Effects 0.000 description 4
- 235000021552 granulated sugar Nutrition 0.000 description 4
- 238000004806 packaging method and process Methods 0.000 description 4
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
- 239000000654 additive Substances 0.000 description 3
- 235000013361 beverage Nutrition 0.000 description 3
- 230000006837 decompression Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000009413 insulation Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 241000723353 Chrysanthemum Species 0.000 description 2
- 235000007516 Chrysanthemum Nutrition 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 229930003268 Vitamin C Natural products 0.000 description 2
- 239000002253 acid Substances 0.000 description 2
- 230000000996 additive effect Effects 0.000 description 2
- DTOSIQBPPRVQHS-PDBXOOCHSA-N alpha-linolenic acid Chemical compound CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 description 2
- 239000003963 antioxidant agent Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 235000006708 antioxidants Nutrition 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 235000021466 carotenoid Nutrition 0.000 description 2
- CEYULKASIQJZGP-UHFFFAOYSA-L disodium;2-(carboxymethyl)-2-hydroxybutanedioate Chemical compound [Na+].[Na+].[O-]C(=O)CC(O)(C(=O)O)CC([O-])=O CEYULKASIQJZGP-UHFFFAOYSA-L 0.000 description 2
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 229910001385 heavy metal Inorganic materials 0.000 description 2
- 230000000215 hyperchromic effect Effects 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 239000004530 micro-emulsion Substances 0.000 description 2
- 230000008520 organization Effects 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 2
- 229920000053 polysorbate 80 Polymers 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 229960003080 taurine Drugs 0.000 description 2
- 235000019154 vitamin C Nutrition 0.000 description 2
- 239000011718 vitamin C Substances 0.000 description 2
- 235000008210 xanthophylls Nutrition 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical group CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 235000020661 alpha-linolenic acid Nutrition 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 150000001721 carbon Chemical group 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000031891 intestinal absorption Effects 0.000 description 1
- 229960004488 linolenic acid Drugs 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000012053 oil suspension Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 230000000529 probiotic effect Effects 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/38—Other non-alcoholic beverages
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Non-Alcoholic Beverages (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention relates to lutein ester or lutein emulsion and a preparation method of the lutein ester or lutein emulsion, and aims at solving the problems that the stability and the water solubility of the lutein ester or lutein are poor, and the bioavailability is low. The emulsion is composed of the lutein ester or lutein, a solvent, an emulsifying agent, an auxiliary emulsifying agent, water and the like. The transparent or semi-transparent O/W type lutein ester emulsion is prepared by adopting a micro-emulsifying technology. The method is easy to operate and low in energy consumption, and is suitable for industrial production. The prepared lutein ester emulsion is uniform and has the strong stability, and can be diluted by adding the water at any ratio; and meanwhile, the system compatibility is good, and a plurality of beneficial components including amino acids, minerals, probiotics and the like can be compounded. The lutein ester or lutein emulsion can be widely applied to industries including health products, functional beverages, cosmetics, medicines and the like.
Description
Technical field
The invention belongs to the preparing technical field of lutein ester bulk formulation, be specifically related to a kind of lutein ester or lutein emulsion and preparation method.
Background technology
Lutein, has another name called " Lutein ", is a kind of natural materials be extensively present in the plants such as vegetables, flowers, fruit, belongs to " carotenoids class " race's material.Research finds, lutein is a kind of excellent antioxidant, in vision protection and pre-anti-cancer and angiocardiopathy etc., have definite effect.But human body cannot synthesize lutein voluntarily, meal supplement must be passed through.Lutein has food, the auxiliary pharmaceutical adjuvant of double effects (hyperchromic and nutrition) as one, because of the biologically active of its uniqueness, will be subject to people and more and more pay close attention in food processing and health medicine.Lutein ester is a kind of important carotenoid fatty acid ester, proterties: reddish brown fine particle.Primary structure to be connected by the long-chain of conjugated double bond containing ten eight carbon atom by two six-membered carbon rings and to form, molecular weight: 1045.71 molecular formula: C
72h1
16o
4.
In plant, lutein mainly exists with the form of lutein ester, and lutein ester easily can must be converted into free lutein in vivo, and meanwhile, human body, the absorption of animal to lutein ester are better than free xanthophyll.Kening Co., Ltd of Germany once pointed out " lutein ester compound decomposes the bioavailability of the lutein obtained, higher than nonesterified lutein by 61.6% ".Owing to there is multiple conjugated double bond in lutein ester molecular structure, cause the effects such as its easy light, oxygen, moisture, high temperature, heavy metal and degrade, and water insoluble, be slightly soluble in fat and oil, low through intestinal absorption rate after oral, this strongly limits the application of lutein ester.Therefore how to improve its water-soluble and stability, expanding its scope of application is that those skilled in the art are making great efforts always.
Publication number CN102949349A provides a kind of stable xanthophyll preparation and preparation method thereof.The stable form increasing free lutein is reached by lutein being loaded into microballoon.But need to use a large amount of volatile organic solvent acetic acid ethyl dissolution microballoon wall materials and lutein in preparation process.
Publication number CN10247569A relates to the preparation technology of the stable water-soluble lutein of a kind of water-soluble good nature.Solvent-free decompression melting method is adopted to prepare water-soluble lutein.After at least two kinds of mixing in lutein, emulsifying agent and additives, decompression (vacuum is in 0.05-1.50 MPa), heating-up temperature is 40-80 DEG C, and temperature retention time is 0.5-3 hour, then cools rapidly, dry, pulverize and forms.This technique is more complicated, higher to equipment requirement, and energy consumption is high.
Publication number CN101836954B provides a kind of stable xanthophyll-oil suspension preparation method, lutein and vegetable oil mix at a certain temperature, pass through high pressure homogenizer, make lutein with micron-sized particle suspension in vegetable oil, degassed through decompression, dividing is filled in packaging, lucifuge sealed type storage.But lutein suspension prepared by the method is water-soluble poor, limits the range of application of product.
Summary of the invention
The object of the invention is for problem existing in above technology, provide a kind of low energy consumption, the lutein ester emulsion of high security and preparation method, emulsion prepared by this method is transparent or semitransparent shape, there is good storage stability, can be used as nutrient prime replenisher and be applied to the field such as health food, functional beverage, also can be used as painted for product of pigment additive.
The technical scheme that the present invention realizes object is as follows:
A kind of lutein ester emulsion, be made up of lutein ester, vitamin E oil, emulsifying agent, assistant for emulsifying agent and water, described lutein ester, solvent, emulsifying agent and assistant for emulsifying agent are 1:1-10:1-20:1-20 by weight, described lutein ester dissolves in a solvent, be present in the emulsion system be made up of emulsifying agent, assistant for emulsifying agent and water in the lump with the form of oily drop with solvent, the particle diameter of oily drop is nanometer or micron order.
And, described solvent vitamin E oil.
And also add vegetable oil, described vegetable oil is at least one in perilla herb oil, linseed oil.
And described emulsifying agent comprises at least one in tween, sucrose fatty ester SE12-16, polyglyceryl fatty acid ester, soybean lecithin, lecithin, Crodaret.
And, glycerol polymerization degree >=3 in described polyglyceryl fatty acid ester, HLB value 8 ~ 18.
And described polyglyceryl fatty acid ester comprises at least one in the pungent decylate of three polyglycereol lists, trimerization glyceryl monolaurate, four polyglycereol monolaurates, six polyglycereol monolaurates, six polyglycerol monooleate, ten polyglycerol monooleate, ten polyglycereol monolaurates, ten polyglycereol list caprylates.
And described assistant for emulsifying agent is at least one in ethanol, ethylene glycol, polyethylene glycol, propane diols, glycerine, n-butanol, D-sorbite, maltitol.
A kind of food, drink or health products containing lutein ester emulsion.
Prepare a method for lutein ester emulsion, step is as follows:
(1) lutein ester crystal to be joined in solvent and to be heated to 40-100 DEG C, stirring and lutein ester is dissolved completely become clear solution;
(2), by joining in above-mentioned solution after emulsifying agent and assistant for emulsifying agent mixing, continuing dispersed with stirring even, being designated as A liquid;
(3) water is joined in A liquid, stir while add waterside, obtain the lutein ester emulsion of transparent or semitransparent shape.
A kind of lutein emulsion, be made up of lutein, vitamin E oil, emulsifying agent, assistant for emulsifying agent and water, described lutein ester, solvent, emulsifying agent and assistant for emulsifying agent are 1:1-10:1-20:1-20 by weight, described lutein ester dissolves in a solvent, be present in the emulsion system be made up of emulsifying agent, assistant for emulsifying agent and water in the lump with the form of oily drop with solvent, the particle diameter of oily drop is nanometer or micron order.
The advantage that the present invention obtains and beneficial effect are:
1, the O/W type lutein ester emulsion that the present invention is prepared by micro-emulsion technology, lutein ester crystal to be dissolved completely in solvent in vitamin E oil, vitamin E oil is all be used as antioxidant before this, the present invention adopts vitamin E oil to use as solvent first, vitamin E oil has non-oxidizability simultaneously, the several functions such as anti-scheroma, ester phase is formed after dissolve lutein ester or lutein, after microemulsified, form particle diameter is again nanometer or micron-sized drop, improve the solubilizing amount of lutein ester, because drop has large specific surface and surfactant molecule, easily adsorb on gastrointestinal tract wall, lutein ester is more easily absorbed, bioavilability improves, simultaneously due to the protection of surfactant, avoid light, oxygen, moisture, high temperature, the factors such as heavy metal are to the destruction of lutein ester, the stability of lutein ester is improved.
2, the product transparency prepared of the present invention is high, thermodynamic stability good, system is compatible good, except lutein ester, can also add other nutriments such as amino acid, probiotic, trace element.
3, the method that the present invention adopts only needs simple mechanical agitation, can form nanometer or the micron order emulsion of transparent or semitransparent shape at ambient temperature, and preparation technology is simple, and energy consumption is low, is applicable to suitability for industrialized production.
4, the solvent that uses of the present invention can, completely except dissolve lutein crystalline esters, can also add and have multiple beneficial function vegetable oil except vitamin E oil.Wherein, perilla herb oil and linseed oil contain abundant alpha-linolenic acid, can increase intelligence, improve memory, vision protection, improving water flood etc..
5, the polyglyceryl fatty acid ester class emulsifying agent security of the present invention's use is high, human test results is shown, the nontoxic sexology movement of polyglyceryl fatty acid ester, have no side effect, decomposable asymmetric choice net in body metabolism process, thus participate in metabolism, be immediately used by the body, having tight security, is a class highly effective and safe additive, food and agricultural organization of united state and the World Health Organization (FAO/WHO) recommendation.
6, product of the present invention can be widely used in the industries such as health products, drinks, cosmetics, medicine.
Accompanying drawing explanation
Fig. 1 is the light microscope figure that embodiment 1 lutein ester emulsion amplifies 1000 times;
Fig. 2 is sample drawing, and wherein, Fig. 2-1 left side is embodiment 1 sample drawing, and Fig. 2-2 is embodiment 2 sample drawing.
Detailed description of the invention
Below by specific embodiment, the invention will be further described, and following examples are descriptive, is not determinate, can not limit protection scope of the present invention with this.
A kind of lutein ester emulsion, is made up of lutein ester or lutein, solvent, emulsifying agent, assistant for emulsifying agent and water, and described lutein ester, solvent, emulsifying agent and assistant for emulsifying agent are 1:1-10:1-20:1-20 by weight.Described lutein ester dissolves in a solvent, and be present in the emulsion system be made up of emulsifying agent, assistant for emulsifying agent and water in the lump with the form of oily drop with solvent, the particle diameter of oily drop is nanometer or micron order.
Preparation method comprises the following steps:
(1) lutein ester crystal or lutein to be joined in solvent and to be heated to 40-100 DEG C, stirring and lutein ester is dissolved completely become clear solution;
(2), by joining in above-mentioned solution after emulsifying agent and assistant for emulsifying agent mixing, continuing dispersed with stirring even, being designated as A liquid;
(3) water is joined in A liquid, stir while add waterside, obtain the lutein ester emulsion of transparent or semitransparent shape.
If (4) need to make other functional products, can suitably add other compositions.
Various compositions in above-mentioned steps are described as follows:
Described solvent vitamin E oil, also adds vegetable oil, and described vegetable oil is at least one in perilla herb oil, linseed oil.
Described emulsifying agent comprises at least one in tween, sucrose fatty ester SE12-16, polyglyceryl fatty acid ester, soybean lecithin, lecithin, Crodaret.Glycerol polymerization degree >=3 in polyglyceryl fatty acid ester, HLB value 8 ~ 18.Polyglyceryl fatty acid ester includes but not limited at least one in the pungent decylate of three polyglycereol lists, trimerization glyceryl monolaurate, four polyglycereol monolaurates, six polyglycereol monolaurates, six polyglycerol monooleate, ten polyglycerol monooleate, ten polyglycereol monolaurates, ten polyglycereol list caprylates.
Described assistant for emulsifying agent is at least one in ethanol, ethylene glycol, polyethylene glycol, propane diols, glycerine, n-butanol, D-sorbite, maltitol.
Embodiment 1
A kind of lutein ester emulsion and preparation method, prepared by this embodiment is by 10g lutein ester crystal, 100mL vitamin E oil, 150g ten polyglycereol single month acid esters, 5g Tween 80, the lutein ester emulsion of 200g propane diols and 500mL water composition.
The step of preparation method is as follows:
(1) accurately taking 10g lutein ester crystal joins in the oil phase of 100mL vitamin E oil composition, and 80 DEG C of insulation to crystal dissolve formation clear solution completely.
(2) accurately take 150g ten polyglycereol single month acid esters, 5g Tween 80 and 200g mixed with propylene glycol evenly after join in the clear solution of above-mentioned preparation.Continue to stir, be designated as A liquid.
(3) in A liquid, slowly add 500mL water under agitation, form the lutein ester emulsion of transparent or semitransparent shape.Filter, sterilizing, packaging.
Product prepared by this embodiment can be used for the hyperchromic field of food.
Embodiment 2
A kind of vision protecting foodstuff containing lutein ester emulsion and preparation method; the microemulsion system be made up of 10g lutein ester crystal, 25mL vitamin E oil, 25mL perilla herb oil, 100g six polyglycereol monolaurate, 150g glycerine and 30L water prepared by this embodiment; add 5L chrysanthemum extract liquid, 8L fructus lycii extracted solution, 2kg white granulated sugar, 200g vitamin C and 150g taurine simultaneously, be prepared into health products.
The step of preparation method is as follows:
(1) accurately taking 10g lutein ester crystal joins in the oil phase of 50mL vitamin E oil composition, and 60 DEG C of insulation to crystal dissolve formation clear solution completely.
(2) accurately take after 100g six polyglycereol monolaurate and 150g glycerine mix and join in the clear solution of above-mentioned preparation.Continue to stir, be designated as A liquid.
(3) in A liquid, slowly add 30L water under agitation, form the lutein ester emulsion of transparent or semitransparent shape.
(4) continue to add 5L chrysanthemum extract liquid, 8L fructus lycii extracted solution, 2kg white granulated sugar, 200g vitamin C and 150g taurine in lutein ester emulsion, mix, filter, sterilizing, packaging.
This product can be used for the field of health care products improving eyesight.
Embodiment 3
A kind of beverage and preparation method containing lutein ester emulsion, prepared by this embodiment is by 10g lutein ester crystal, 20mL vitamin E oil, 100g soybean lecithin, 50g sucrose fatty ester SE16,200g ethanol and 500L water, then adds the beverage of 20kg white granulated sugar, 25kg inspissated juice, 500g citric acid, the formation of 300g natrium citricum.
The step of preparation method is as follows:
(1) accurately taking 10g lutein ester crystal joins in 20mL vitamin E oil, and 100 DEG C of insulation to crystal dissolve formation clear solution completely.
(2) accurately take after 100g soybean lecithin, 50g sucrose fatty ester SE16 and 200g ethanol mix and join in the clear solution of above-mentioned preparation.Continue to stir, be designated as A liquid.
(3) in A liquid, slowly add 500L water under agitation, form the lutein ester emulsion of transparent or semitransparent shape.
(4) in emulsion, add 20kg white granulated sugar, 25kg inspissated juice, 500g citric acid, 300g natrium citricum, mix, filter, sterilizing, packaging.
This product can be applicable to field of beverage.
Claims (10)
1. a lutein ester emulsion, it is characterized in that: be made up of lutein ester, vitamin E oil, emulsifying agent, assistant for emulsifying agent and water, described lutein ester, solvent, emulsifying agent and assistant for emulsifying agent are 1:1-10:1-20:1-20 by weight, described lutein ester dissolves in a solvent, be present in the emulsion system be made up of emulsifying agent, assistant for emulsifying agent and water in the lump with the form of oily drop with solvent, the particle diameter of oily drop is nanometer or micron order.
2. lutein ester emulsion according to claim 1, is characterized in that: described solvent vitamin E oil.
3. vegetable oil according to claim 2, is characterized in that: also add vegetable oil, and described vegetable oil is at least one in perilla herb oil, linseed oil.
4. lutein ester emulsion according to claim 1, is characterized in that: described emulsifying agent comprises at least one in tween, sucrose fatty ester SE12-16, polyglyceryl fatty acid ester, soybean lecithin, lecithin, Crodaret.
5. lutein ester emulsion according to claim 4, is characterized in that: glycerol polymerization degree >=3 in described polyglyceryl fatty acid ester, HLB value 8 ~ 18.
6. lutein ester emulsion according to claim 5, is characterized in that: described polyglyceryl fatty acid ester comprises at least one in the pungent decylate of three polyglycereol lists, trimerization glyceryl monolaurate, four polyglycereol monolaurates, six polyglycereol monolaurates, six polyglycerol monooleate, ten polyglycerol monooleate, ten polyglycereol monolaurates, ten polyglycereol list caprylates.
7. lutein ester emulsion according to claim 1, is characterized in that: described assistant for emulsifying agent is at least one in ethanol, ethylene glycol, polyethylene glycol, propane diols, glycerine, n-butanol, D-sorbite, maltitol.
8. food, drink or the health products containing lutein ester emulsion according to claim 1.
9. prepare a method for the lutein ester emulsion as described in claim 1-8, it is characterized in that: step is as follows:
(1) lutein ester crystal to be joined in solvent and to be heated to 40-100 DEG C, stirring and lutein ester is dissolved completely become clear solution;
(2), by joining in above-mentioned solution after emulsifying agent and assistant for emulsifying agent mixing, continuing dispersed with stirring even, being designated as A liquid;
(3) water is joined in A liquid, stir while add waterside, obtain the lutein ester emulsion of transparent or semitransparent shape.
10. a lutein emulsion, it is characterized in that: be made up of lutein, vitamin E oil, emulsifying agent, assistant for emulsifying agent and water, described lutein ester, solvent, emulsifying agent and assistant for emulsifying agent are 1:1-10:1-20:1-20 by weight, described lutein ester dissolves in a solvent, be present in the emulsion system be made up of emulsifying agent, assistant for emulsifying agent and water in the lump with the form of oily drop with solvent, the particle diameter of oily drop is nanometer or micron order, described solvent vitamin E oil.
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