CN104352856B - 一种治疗复发性口腔溃疡的中药组合物 - Google Patents

一种治疗复发性口腔溃疡的中药组合物 Download PDF

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CN104352856B
CN104352856B CN201410625057.0A CN201410625057A CN104352856B CN 104352856 B CN104352856 B CN 104352856B CN 201410625057 A CN201410625057 A CN 201410625057A CN 104352856 B CN104352856 B CN 104352856B
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魏本雪
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Abstract

本发明公开了一种治疗复发性口腔溃疡的中药组合物，属于中药领域。其是由下述重量份的原料药制成：青黛10、太子参10、桑椹8、赤小豆8、马鞭草10、鱼腥草8、天葵子6、夏枯草6、天南星6、徐长卿6、野菊花12、玉米须8、秦艽6、淡竹叶12、皂角刺6、紫草8、酸枣仁12、蜂房8、土茯苓8、王不留行6。本发明采用天然中药为原料，疗效确切且无毒副作用，能有效治愈复发性口腔溃疡且不易复发，有效率达98％。

Description

一种治疗复发性口腔溃疡的中药组合物
技术领域
本发明涉及一种治疗复发性口腔溃疡的中药组合物，属于中药领域。
背景技术
复发性阿弗他溃疡，又称复发性阿弗他口炎、复发性口腔溃疡、复发性口疮，是口腔黏膜疾病中发病率最高的一种疾病，普通感冒、消化不良、精神紧张、郁闷不乐等情况均能偶然引起该病的发生，好发于唇、颊、舌缘等，在黏膜的任何部位均能出现，但在角化完全的附着龈和硬腭则少见。发病年龄一般在10～30岁之间，女性较多，一年四季均能发生。复发性阿弗他溃疡有自限性，能在10天左右自愈。该病具有周期性、复发性及自限性等特点。
目前治疗复发性口腔溃疡有内服消炎药、粉状药剂外敷等方法，但治疗效果不明显，特别是用外敷法，疼痛加剧、流涎不止，病人难以接受。
发明内容
本发明的目的在于提供一种治疗复发性口腔溃疡的中药组合物，该中药组合物疗效确切、见效快且无毒副作用。
本发明的技术方案是：
一种治疗复发性口腔溃疡的中药组合物，是由下述重量份的原料药制成：青黛10、太子参10、桑椹8、赤小豆8、马鞭草10、鱼腥草8、天葵子6、夏枯草6、天南星6、徐长卿6、野菊花12、玉米须8、秦艽6、淡竹叶12、皂角刺6、紫草8、酸枣仁12、蜂房8、土茯苓8、王不留行6。
配制及服用方法：水煎服，每日一剂，分早晚两次饭后服用。
各中药的药理作用：
青黛：咸，寒。归肝经。功效与主治：清热解毒，凉血，定惊。用于温毒发斑，血热吐衄，胸痛咳血，口疮，痄腮，喉痹，小儿惊痫。
太子参：甘、微苦，平。归脾、肺经。功效与主治：益气健脾，生津润肺。用于脾虚体倦，食欲不振，病后虚弱，气阴不足，自汗口渴，肺燥干咳。
桑椹：甘、酸，寒。归心、肝、肾经。功效与主治：补血滋阴，生津润燥。用于眩晕耳鸣，心悸失眠，须发早白，津伤口渴，内热消渴，血虚便秘。
赤小豆：甘、酸，平。归心、小肠经。功效与主治：利水消肿，解毒排脓。用于水肿胀满，脚气肢肿，黄疸尿赤，风湿热痹，痈肿疮毒，肠痈腹痛。
马鞭草：苦，凉。归肝、牌经。功效与主治：活血散瘀，截疟，解毒，利水消肿。于癥瘕积聚，经闭痛经，疟疾，喉痹，痈肿，水肿，热淋。
鱼腥草：辛，微寒。归肺经。功效与主治：清热解毒，消痈排脓，利尿通淋。用于肺痈吐脓，痰热喘咳，热痢，热淋，痈肿疮毒。
天葵子：甘、苦，寒。归肝、胃经。功效与主治：清热解毒，消肿散结。用于痈肿疔疮，乳痛，瘰病，毒蛇咬伤。
夏枯草：辛、苦，寒。归肝、胆经。功效与主治：清火，明目，散结，消肿。用于目赤肿痛，目珠夜痛，头痛眩晕，瘰疬，瘿瘤，乳痈肿痛；甲状腺肿大，淋巴结结核，乳腺增生，高血压。
天南星：苦、辛，温；有毒。归肺、肝、脾经。功效与主治：燥湿化痰，祛风止痉，散结消肿。用于顽痰咳嗽，风瘫眩晕，中风痰壅，口限歪斜，半身不遂；癫痫，惊风，破伤风。生用外治痈肿，蛇虫咬伤。
徐长卿：辛，温。归肝、胃经。功效与主治：祛风化湿，止痛止痒。用于风湿痹痛，胃痛胀满，牙痛，腰痛，跌扑损伤；荨麻疹，湿疹。
野菊花：苦、辛，微寒。归肝、心经。功效与主治：清热解毒。用于疔疮痈肿，目赤肿痛。头痛眩晕。
玉米须：甘，平。归膀胱、肝、胆经。功效与主治：利胆退黄，利尿退肿，止血。治肾炎水肿，脚气，黄疸肝炎，高血压，胆囊炎，胆结石，糖尿病，吐血衄血，鼻渊，乳痈。
秦艽：辛、苦，平。归胃、肝、胆经。功效与主治：祛风湿，清湿热，止痹痛。用于风湿痹痛，筋脉拘挛，骨节酸痛，日哺潮热，小儿疳积发热。
淡竹叶：甘、淡，寒。归心、胃、小肠经。功效与主治：清热除烦，利尿。用于热病烦渴，小便赤涩淋痛，口舌生疮。
皂角刺：辛，温。归肝、胃经。功效与主治：消肿托毒，排脓，杀虫。用于痈疽初起或脓成不溃；外治疥癣麻风。
紫草：甘、咸，寒。归心、肝经。功效与主治：凉血，活血，解毒透疹。用于血热毒盛，班疹紫黑，麻疹不透，疮疡，湿疹，水火烫伤。
酸枣仁：甘、酸，平。归肝、胆、心经。功效与主治：补肝，宁心，敛汗，生津。用于虚烦不眠，惊悸多梦，体虚多汗，津伤口渴。
蜂房：甘，平。归胃经。功效与主治：祛风，攻毒，杀虫，止痛。于龋齿牙痛，疮疡肿毒，乳痈，瘰疬，皮肤顽癣，鹅掌风。
土茯苓：甘、淡，平。归肝、胃经。功效与主治：除湿，解毒，通利关节。用于湿热淋浊，带下，痈肿，瘰病，疥癣，梅毒及汞中毒所致的肢体拘挛，筋骨疼痛。
王不留行：苦，平。归肝，胃经。功效与主治：活血通经，下乳消肿。用于乳汁不下，经闭，痛经，乳痈肿痛。
本发明的有益效果是：本发明采用天然中药为原料，疗效确切且无毒副作用，能有效治愈复发性口腔溃疡且不易复发，有效率达98％。
以下结合临床试验对本发明进一步说明。
一、临床试验
1、临床资料：2012年6月至2014年6月两年间，共观察16-57岁的复发性口腔溃疡患者100例，其平均年龄为32.5岁。
2、诊断依据：
(1)、以口腔粘膜出现单个或数个直径3～5mm的溃疡，灼热疼痛为主要症状；
(2)、起病较快，一般7天左右愈合，若此伏彼起，则病程延长。愈后常易复发；
(3)、口腔检查：口腔粘膜溃疡较表浅，圆形或椭圆形，数量少则1～2个，多则10余个，表面有淡黄色分泌物附着，溃疡周围粘膜大多充血。
3、治疗方法：其中治疗组服用本发明中药，水煎服，每日一剂，分早晚两次饭后服用，3天为1个疗程。
4、疗效判定标准：
痊愈：复发性口腔溃疡愈合，局部无不适感；
好转：口疮虽然时有复发，但数量减少，程度减轻；
无效：口疮症状及溃疡无明显变化。
5、治疗结果：在临床使用本发明药物，服药的100例患者，服药1个疗程后，症状明显缓解，继续服药1个疗程后，痊愈87例，有效11例，总有效率为98％。
具体实施方式
实施例1
配比(单位：重量份)：
青黛10、太子参10、桑椹8、赤小豆8、马鞭草10、鱼腥草8、天葵子6、夏枯草6、天南星6、徐长卿6、野菊花12、玉米须8、秦艽6、淡竹叶12、皂角刺6、紫草8、酸枣仁12、蜂房8、土茯苓8、王不留行6。
配制及服用方法：水煎服，每日一剂，分早晚两次饭后服用。

Claims (1)

1.一种治疗复发性口腔溃疡的中药组合物，其特征在于，是由下述重量份的原料药制成：青黛10、太子参10、桑椹8、赤小豆8、马鞭草10、鱼腥草8、天葵子6、夏枯草6、天南星6、徐长卿6、野菊花12、玉米须8、秦艽6、淡竹叶12、皂角刺6、紫草8、酸枣仁12、蜂房8、土茯苓8、王不留行6。
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