CN104352781A - Traditional Chinese medicine preparation for treating rectal cancer and preparation method thereof - Google Patents
Traditional Chinese medicine preparation for treating rectal cancer and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating rectal cancer and a preparation method thereof and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine preparation comprises the following raw materials: semen boitae, artocarpus heterophyllus, picrorhiza scrophulariiflora pennell, Yunnan bulbophyllum herb, averrhoa carambola, polygonum runcinatum, bauhinia purpurea, subprostrate sophora, viburnum cylindricum leaves, citrus aurantium, rubus idaeus, folium nelumbinis, carica papaya, radix puerariae, bidens pilosa and fructus chebulae. The traditional Chinese medicine preparation and the preparation method thereof have the benefits that the medicinal materials selected by the traditional Chinese medicine preparation are reasonable in compatibility, and the traditional Chinese medicine preparation conforms to the theory of traditional Chinese medicine and pharmacy and modern medicine and pharmacology, has the efficacies of regulating the flow of Qi and removing blood stasis, clearing away heat and detoxifying, and dispelling wind and eliminating dampness, has a special treatment effect on the rectal cancer caused by various inflammations, has the advantages of high simplicity in the manufacture of the medicinal materials, good convenience for taking, high safety and reliability, no any toxic and side effects, low cost and obvious treatment effect, can achieve the purpose of treating both symptoms and root causes in the treatment of the rectal cancer and is worthy of wide clinical popularization and application.
Description
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of rectal cancer.
Background technology
Cancer between rectal cancer refers to from pectinate line to proctosigmoid intersection is one of modal malignant tumor of digestive tract.Rectal cancer position is low, is easily diagnosed by rectal touch and romanoscope, but because going deep into pelvic cavity in its position, anatomy relationship is complicated, and operation is not easily thorough, and Postoperative recurrent rate is high.Middle and lower rectal carcinoma and anal sphincter close, being difficult to the difficult problem that anus preserving and function thereof are operations during operation, is also operation method is argued maximum a kind of diseases.China's rectal cancer age of onset median is at one's mid-40s, and adolescence's sickness rate has the trend of rising.
The cause of disease of rectal cancer is still not fully aware of at present, and its morbidity is relevant with social environment, dietary habit, inherited genetic factors etc.Rectal polyp is also the high risk factor of rectal cancer.Substantially be recognized that Animal fat and protein are taken in too high at present, dietary fiber Deficiency of Intake is the high risk factor that rectal cancer occurs.
At present, domesticly there is no effective method and medicine is used for the treatment of rectal cancer.Usually Therapeutic Method used is the method for doctor trained in Western medicine excision, but most patient with operation life-span can only delay less than one-year age, and the patient living through 3 years is few.Therefore, up to the present, regardless of intravenously administrable or oral administration, all do not reach the object of healing, rectal cancer is a kind of disease of serious harm people health.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of rectal cancer; Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of regulating the flow of QI to dissipate blood stasis, heat-clearing and toxic substances removing, expelling wind and removing dampness, to the rectal cancer that various inflammation causes, there is unique curative effect, medical material makes simple, taking convenience, safe and reliable, without any side effects, with low cost, evident in efficacy, the object for the treatment of both the principal and secondary aspects of a disease can be reached to the treatment of rectal cancer, clinic wide popularization and application.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for rectal cancer, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Platycladi 32 ~ 55 portions of Fructus Artocarpi Heterophyllis 29 ~ 53 parts of Rhizoma Picrorhizae 28 ~ 52 parts of Herba Bulbophylli inconspicui 25 ~ 49 parts
18 ~ 42 parts, carambola 25 ~ 49 parts of Herba Polygoni Runcinatis 23 ~ 45 parts of Bauhinia purpureas 20 ~ 44 parts of good rattans
Rub 15 ~ 39 parts, Bai Ye 17 ~ 41 parts of bigarabes 17 ~ 41 parts purple bubble 16 ~ 40 parts of Folium Nelumbinis
Fructus Caricae 13 ~ 35 parts of Radix Puerariaes 13 ~ 31 portions of Herba Bidentis Bipinnatae 11 ~ 29 parts of Fructus Chebulaes 5 ~ 29 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Platycladi 36 ~ 51 portions of Fructus Artocarpi Heterophyllis 33 ~ 49 parts of Rhizoma Picrorhizae 32 ~ 48 parts of Herba Bulbophylli inconspicui 29 ~ 45 parts
22 ~ 38 parts, carambola 29 ~ 45 parts of Herba Polygoni Runcinatis 26 ~ 42 parts of Bauhinia purpureas 24 ~ 40 parts of good rattans
Rub 19 ~ 35 parts, Bai Ye 21 ~ 37 parts of bigarabes 21 ~ 37 parts purple bubble 20 ~ 36 parts of Folium Nelumbinis
Fructus Caricae 16 ~ 32 parts of Radix Puerariaes 16 ~ 28 portions of Herba Bidentis Bipinnatae 14 ~ 26 parts of Fructus Chebulaes 9 ~ 25 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Platycladi 40 ~ 47 portions of Fructus Artocarpi Heterophyllis 37 ~ 45 parts of Rhizoma Picrorhizae 36 ~ 44 parts of Herba Bulbophylli inconspicui 33 ~ 41 parts
26 ~ 34 parts, carambola 33 ~ 41 parts of Herba Polygoni Runcinatis 30 ~ 38 parts of Bauhinia purpureas 28 ~ 36 parts of good rattans
Rub 23 ~ 31 parts, Bai Ye 25 ~ 33 parts of bigarabes 25 ~ 33 parts purple bubble 24 ~ 32 parts of Folium Nelumbinis
Fructus Caricae 20 ~ 28 parts of Radix Puerariaes 19 ~ 25 portions of Herba Bidentis Bipinnatae 17 ~ 23 parts of Fructus Chebulaes 13 ~ 21 parts.
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Platycladi 43 portions of Fructus Artocarpi Heterophyllis 41 parts of Rhizoma Picrorhizae 40 parts of Herba Bulbophylli inconspicui 37 parts
30 parts, carambola 37 parts of Herba Polygoni Runcinatis 34 parts of Bauhinia purpureas 32 parts of good rattans
Rub 27 parts, Bai Ye 29 parts of bigarabes 29 parts purple bubble 28 parts of Folium Nelumbinis
Fructus Caricae 24 parts of Radix Puerariaes 22 portions of Herba Bidentis Bipinnatae 20 parts of Fructus Chebulaes 17 parts.
Treat a preparation method for the Chinese medicine preparation of rectal cancer, comprise following processing step:
(1) Semen Platycladi, Fructus Artocarpi Heterophylli, carambola, Bauhinia purpurea, good rattan, Zi Pao, Folium Nelumbinis, Fructus Caricae and Fructus Chebulae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Rhizoma Picrorhizae, bigarabe and Herba Bidentis Bipinnatae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) by Herba Bulbophylli inconspicui, Herba Polygoni Runcinati with rub Bai Ye and clean, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaims ethanol, and filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(4) Radix Puerariae is put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(5) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the Chinese medicine preparation for the treatment of rectal cancer of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
Semen Platycladi: sweet in the mouth, property is put down; GUIXIN, kidney, large intestine channel.Tranquilizing by nourishing the heart, hidroschesis intestine moistening.For fidgets due to deficiency insomnia, severe palpitation, night sweat due to yin deficiency, dryness of the intestine constipation." detailed outline " carries: " nourish heart gas, and profit kidney is dry, and Fructus Alpiniae Oxyphyllae is allayed excitement; Burn drop and control scabies.”
Fructus Artocarpi Heterophylli: sweet in the mouth, micro-acid, property is put down, nontoxic.To promote the production of body fluid relieving restlessness, relieving acute alcoholism and recuperating the spleen." detailed outline " carries: " quenching the thirst, it is tired to separate, relieving alcoholic intoxication, QI invigorating." modern medicine study finds that Fructus Artocarpi Heterophylli has antioxidation, antibacterial, antiinflammatory, adjunct antineoplastic, check melanin generate and effect of auxiliary hyperglycemic.
Rhizoma Picrorhizae: bitter in the mouth, cold in nature; Return liver, stomach, large intestine channel.Reducing the asthenic fever, disappear infantile malnutrition with fever, heat clearing and damp drying, eliminating fire and detoxication.Cure mainly deficiency of YIN hectic fever due to YIN-deficiency, hectic fever night sweat, infant malnutrition, damp-heat dysentery, jaundice, spit blood, epistaxis, conjunctival congestion and swelling pain, carbuncle skin infection, hemorrhoid toxic swelling.Modern medicine study confirms, the Piperonyl methyl acetone that Rhizoma Picrorhizae includes has the effect of hepatic cholagogic.
Herba Bulbophylli inconspicui: sweet in the mouth, light, cool in nature; Enter lung, stomach two warp.Nourishing YIN and clearing away heat, preventing phlegm from forming and stopping coughing.For xeropulmonary cough, hemoptysis of pulmonary tuberculosis, calentura excessive thirst, tonsillitis.Guangzhou army " conventional Chinese herbal medicine handbook " carries: " moistening the lung and resolving phlegm, tonifying-Yin and nourishing-stomach.Control pulmonary tuberculosis cough, spitting of blood, cough due to chronic tracheitis, pneumonia convalescent period, chronic pharyngalgia, chronic gastritis, achlorhydria, inappetence, seminal emission.”
Carambola: sour in the mouth, sweet, cold in nature; Attach to the lung and stomach meridians.Clearing away heat and promoting production of body fluid, promoting diuresis to remove toxic substance, expelling wind and removing dampness, reducing swelling and alleviating pain.Main air heat cough, pharyngalgia, excessive thirst, stranguria caused by urinary stone, erosion of the oral mucosa, toothache, malaria with splenomegaly, alcoholism, anemopyretic cold, acute gastroenteritis, dysuria, puerperal edema, treating swelling and pain by traumatic injury, swollen ulcer drug." Guangxi Chinese medicinal herbal " carries: " alcoholic intoxication, removing food stagnancy is stagnant.”
Herba Polygoni Runcinati: bitter in the mouth, micro-acid, puckery, property is put down.Heat-clearing and toxic substances removing, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling.For acute gastroenteritis, spitting of blood of spitting blood, bleeding hemorrhoids, menoxenia, traumatic injury; Mastitis are controlled in external, and carbuncle furuncle and phyma poison, controls dysentery, have loose bowels, impairment caused by overstrain lumbago." Chinese herbal medicine is commonly used in Sichuan " carries: " heat clearing away is invigorated blood circulation.Control internal injury, heat in blood giddy headache, redly to collapse, amenorrhea, hypopyretic cough, dysentery with red and white feces, carbuncle poison malignant boil.”
Bauhinia purpurea: micro-puckery is micro-cool.The spleen strengthening and damp drying, nourishing the lung to arrest cough.For dyspepsia, acute gastroenteritis, cough, constipation, antiinflammatory, pneumonia, bronchitis.Modern medicine study confirms, Bauhinia purpurea has the effect such as the spleen strengthening and damp drying, anti-inflammation hemostasia.
Good rattan: bitter in the mouth, cold in nature.Heat-clearing and toxic substances removing, eliminating stasis to stop pain, inducing diuresis for treating stranguria syndrome.Cure mainly affection due to external wind and heat, cough, laryngopharynx swelling and pain, damp-heat dysentery, toothache, traumatic pain, urine leaching is puckery.
Rub Bai Ye: bitter in the mouth, cool in nature.Heat-clearing and toxic substances removing.For traumatic injury, rheumatism bones and muscles pain, nourishing the lung to arrest cough, for xeropulmonary cough, dysentery, acute gastroenteritis, stomatitis, urinary tract infection; Burn and scald is controlled in external, sore swollen toxin, skin pruritus, dispelling, collateral-activating.
Bigarabe: anti-inflammation and sterilization, prevents skin inflammation red and swollen.Modern medicine study confirms, bigarabe can balance skin fat secretion, strengthens cellular metabolism function, promotes cell regeneration, the skin corium that maintenance is impaired, helps hole, cicatrix hole to recover normal as early as possible, effect of desalination pox print.
Purple bubble: bitter in the mouth, puckery, property is flat, tepor.Antidiarrheal dysentery, wind-expelling pain-stopping, clearing away heat-damp and promoting diuresis, antiinflammatory, the kidney invigorating arresting seminal emission.Cure mainly dysentery, diarrhoea, rheumatic arthritis, gout, acute hepatitis, chronic hepatitis, menoxenia, infantile malnutrition, dampen pain, eczema, skin purulent infection, stomatitis, angina, gingivitis, urinary stone, neurasthenia, seminal emission, premature ejaculation.
Folium Nelumbinis: bitter in the mouth is pungent, micro-puckery, cool in nature; GUIXIN, liver, spleen channel.Clearing away summer-heat, sending up the lucid YANG, cooling blood for hemostasis.For summer-heat excessive thirst, diarrhea due to summer heat and dampness, diarrhea due to hypofunction of the spleen, heat in blood tells nosebleed, edema, lack of appetite abdominal distention, dysentery, leucorrhea, proctoptosis, spitting of blood, metrorrhagia of having blood in stool.Burnt FOLIUM NELUMBINIS astringent therapy removing stasis to stop bleeding." occupying diet spectrum with breath " carries: " all part of the body cavity above the diaphragm housing the heart and lungs heresies are contained, and control and clearly should not fall person, can't use.”
Fructus Caricae: sweet in the mouth, property is put down.Invigorating the stomach and promoting digestion, nourishing lactogenic, channels sootheing and network vessel quickening.For weakness of the spleen and stomach, inappetence, hypogalactia, Fengshi Guanjie pain, numb limbs and tense tendons, taste-blindness rate pain.Modern medicine study confirms, Fructus Caricae includes lycopene and possesses remarkable capability of resistance to radiation.
Radix Puerariae: sweet in the mouth, pungent is flat; Enter spleen, stomach warp.Yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, relieving restlessness is temperature only.Cure the wound cold, warm headache stiffness of the nape, and dysphoria with smothery sensation is quenched one's thirst, and has loose bowels, dysentery, and skin eruption is not saturating, hypertension, and angina pectoris is deaf." not Lu " carries: " excessive cold invading middle-JIAO(the spleen and stomach) wind headache of curing the wound, expelling pathogenic factors from muscles, delivers, and perspires, loosing the interspaces of skin and muscles.Treat incised wound, pain relieving, side of body wind pain.Take root juice, treatment is quenched one's thirst, typhoid fever high fever." modern medicine study, Radix Puerariae flavone has cancer-resisting and estrogen-like effects, can promote women's breast enlargement, skin care, especially to middle-aged women and the effect of menopausal women face-nourishing health-care obvious.
Herba Bidentis Bipinnatae: bitter in the mouth, cold nature.Heat-clearing and toxic substances removing, expelling wind and removing dampness, promoting blood circulation and detumescence.Cure mainly malaria, diarrhoea, dysentery, hepatitis, acute nephritis, stomachache, dysphagic, acute appendicitis, laryngopharynx swelling and pain, traumatic injury, snake bite and insect sting.Modern medicine study confirms, the ethanol immersion of Herba Bidentis Bipinnatae has bacteriostasis to gram-positive bacterium in vitro, and flower, stem also have bacteriostasis to staphylococcus aureus.
Fructus Chebulae: sour in the mouth, puckery, property is put down.To astringe the lung astringing intestine to stop diarrhea, therapeutic method to keep the adverse QI flowing downwards sore-throat relieving.Cure mainly chronic diarrhea, chronic dysentery, proctoptosis, phlegmatic cough of breathing with cough, chronic cough aphonia." Japan hanako materia medica " carries: " relieving restlessness, harnesses the river for expectorant, the therapeutic method to keep the adverse QI flowing downwards, and in tune, antidiarrheal dysentery, cholera, renal mass kidney qi, lung qi dyspnea with rapid respiration, digesting and appetizing, hemorrhoidal hamorrhage rushes down blood, metrorrhagia leukorrhagia, five types of dysphagia.”
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and pharmacy and modern medicine theory, and there is effect of regulating the flow of QI to dissipate blood stasis, heat-clearing and toxic substances removing, expelling wind and removing dampness, to the rectal cancer that various inflammation causes, there is unique curative effect, medical material makes simple, taking convenience, safe and reliable, without any side effects, with low cost, evident in efficacy, the object for the treatment of both the principal and secondary aspects of a disease can be reached to the treatment of rectal cancer, clinic wide popularization and application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Semen Platycladi 51g Fructus Artocarpi Heterophylli 49g Rhizoma Picrorhizae 48g Herba Bulbophylli inconspicui 45g
The good rattan 38g of carambola 45g Herba Polygoni Runcinati 42g Bauhinia purpurea 40g
Rub Bai Ye 37g bigarabe 37g purple bubble 36g Folium Nelumbinis 35g
Fructus Caricae 32g Radix Puerariae 28g Herba Bidentis Bipinnatae 26g Fructus Chebulae 25g.
Treat a preparation method for the Chinese medicine preparation of rectal cancer, comprise following processing step:
(1) Semen Platycladi, Fructus Artocarpi Heterophylli, carambola, Bauhinia purpurea, good rattan, Zi Pao, Folium Nelumbinis, Fructus Caricae and Fructus Chebulae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Rhizoma Picrorhizae, bigarabe and Herba Bidentis Bipinnatae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) by Herba Bulbophylli inconspicui, Herba Polygoni Runcinati with rub Bai Ye and clean, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaims ethanol, and filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(4) Radix Puerariae is put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(5) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the Chinese medicine preparation for the treatment of rectal cancer of the present invention.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Semen Platycladi 47g Fructus Artocarpi Heterophylli 45g Rhizoma Picrorhizae 44g Herba Bulbophylli inconspicui 41g
The good rattan 34g of carambola 41g Herba Polygoni Runcinati 38g Bauhinia purpurea 36g
Rub Bai Ye 33g bigarabe 33g purple bubble 32g Folium Nelumbinis 31g
Fructus Caricae 28g Radix Puerariae 25g Herba Bidentis Bipinnatae 23g Fructus Chebulae 21g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Semen Platycladi 43g Fructus Artocarpi Heterophylli 41g Rhizoma Picrorhizae 40g Herba Bulbophylli inconspicui 37g
The good rattan 30g of carambola 37g Herba Polygoni Runcinati 34g Bauhinia purpurea 32g
Rub Bai Ye 29g bigarabe 29g purple bubble 28g Folium Nelumbinis 27g
Fructus Caricae 24g Radix Puerariae 22g Herba Bidentis Bipinnatae 20g Fructus Chebulae 17g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Semen Platycladi 40g Fructus Artocarpi Heterophylli 37g Rhizoma Picrorhizae 36g Herba Bulbophylli inconspicui 33g
The good rattan 26g of carambola 33g Herba Polygoni Runcinati 30g Bauhinia purpurea 28g
Rub Bai Ye 25g bigarabe 25g purple bubble 24g Folium Nelumbinis 23g
Fructus Caricae 20g Radix Puerariae 19g Herba Bidentis Bipinnatae 17g Fructus Chebulae 13g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 5
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
Semen Platycladi 36g Fructus Artocarpi Heterophylli 33g Rhizoma Picrorhizae 32g Herba Bulbophylli inconspicui 29g
The good rattan 22g of carambola 29g Herba Polygoni Runcinati 26g Bauhinia purpurea 24g
Rub Bai Ye 21g bigarabe 21g purple bubble 20g Folium Nelumbinis 19g
Fructus Caricae 16g Radix Puerariae 16g Herba Bidentis Bipinnatae 14g Fructus Chebulae 9g.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of rectal cancer, select the routine clinical observation of rectal cancer patient 200 of making a definite diagnosis, patient is divided into treatment group and matched group two groups at random, treatment group 100 example, wherein male 52 example, women 48 example, 30 ~ 60 years old age, 45 years old mean age, the course of disease 3 years; Matched group 100 example, wherein male 51 example, women 49 example, 31 ~ 61 years old age, 46 years old mean age, the course of disease 2 years.
The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 2 times, each 1 time sooner or later, each 2 (every sheet 0.5g), warm water delivery service after meal; Within 15 days, be 1 course for the treatment of, 3 ~ 4 courses for the treatment of can fully recover, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes gentamycin sulfate granule, oral, one time 1,2 times on the one, sooner or later take after the meal; Maintenance dose one time 1,1 time on the one, the course for the treatment of is depending on the state of an illness.
3, efficacy determination:
(1) cure: clinical symptoms all disappears, and physical recovery is normal.
(2) effective: clinical symptoms obviously alleviates, health recovers to some extent.
(3) effective: clinical symptoms alleviates to some extent, and health obviously recovers.
(4) invalid: by treating rear symptom without alleviating or increasing the weight of.
4, result:
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, section, man, 30 years old, people from Chaoyang.Patient found dyschesia before half a year, find that rectum position has foreign body to block to examination in hospital, be diagnosed as rectal cancer abdominal cavity further extensively to shift, can not perform the operation, under the introduction of ward mate, take after Chinese medicine preparation of the present invention treats 2 courses for the treatment of, check nuclear magnetic resonance, NMR finds that focus has had and significantly reduces, after continuing to take 2 courses for the treatment of of Chinese medicine preparation of the present invention, transference cure, thorough rehabilitation.
2, thunder, female, 42 years old, people from Liaoyuan, Jilin.Patient was diagnosed as before 1 year after rectal cancer surgery through chemotherapy physical rehabilitation half a year, after check, the unexpected sensuously a burst of severe pain of abdominal part of Yu Yi, have a rest and also cannot alleviate, after being sent to hospital, ultrasound diagnosis finds that the huge focus of a diameter about 15 centimetres appears in the liver of uncle Wang, finally be diagnosed as rectal cancer recurrence, recommend to take Chinese medicine preparation of the present invention treatment through doctor, take medicine after 2 courses for the treatment of, symptom is clearly better, after taking 3 courses for the treatment of, transference cure, recovery from illness, follows up a case by regular visits to after 1 year without recurrence.
3, money, man, 35 years old, Shanxi people from Lvliang City.Patient feels that before or after meals belly is swollen every day, defecates rare, goes to toilet every day 7,8 times, has pendant sense, pain after an action of the bowels.Rear pain is aggravated gradually, and the situation of abdominal distention is more and more obvious.Admission examination, enteroscope 16 centimeters of entering are obstructed, and see that mucosal erosion is hemorrhage, and CT prompting has the enclosed mass of 5.8*4.7, makes a definite diagnosis inspection further, is diagnosed as rectal cancer 3 phase.By taking Chinese medicine preparation of the present invention treatment, take medicine after 1 course for the treatment of, CT examination tumor reduces to some extent, and after taking 2 courses for the treatment of, CT examination tumor obviously reduces, and after taking 4 courses for the treatment of, CT examination tumor disappearance, physical recovery is normal, follows up a case by regular visits to so far without recurrence.
4, soup, female, 44 years old, people from Hegang, Heilungkiang.Patient is found suffers from rectal cancer, under the accompanying of layman, patient has come my institute and has gone to a doctor, under the introduction of doctor, take after Chinese medicine preparation of the present invention treats 1 course for the treatment of, the state of an illness takes a turn for the better to some extent, after taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, the state of an illness is clearly better, after taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, and transference cure, recovery from illness, follows up a case by regular visits to after 3 years without recurrence.
5, Yin, female, 60 years old, Zhenjiang, Jiangsu people.Patient before 3 years because of constipation, time and suffer from diarrhoea, diarrhoea alternately occurs being diagnosed as rectal cancer with constipation sometimes.Due to older, patient does not want to perform an operation, and abandons chemotherapy yet.Only accept immunotherapy, after having done two courses for the treatment of, aunt's Wu symptom has slightly been alleviated.But over nearly 3 months, Finding case is had blood in stool relatively more serious, is mucus hemafecia sometimes, weak from head to foot, is off one's feed, also again and again feels sick.Patient specifically dare not be careless, done detailed inspection greatly alarmedly, be diagnosed as rectal cancer recurrence to hospital.Patient has rectal cancer medical history, show as constipation, diarrhoea or the two alternately, increase the weight of 2 months, with weak, be off one's feed, feel sick, sleep not good enough.Doctor advised takes Chinese medicine preparation of the present invention treatment, after taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, stool is just unobstructed, and urine is also limpid many, can suitable out-of-bed activity, eat 2 little bowls of rice every day, have rosy cheeks, after taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, malaise symptoms all disappears, health also energetically youngster, about 8 hours lengths of one's sleep, mood is straightforward.Check rectal cancer is eliminated, take again 1 the course for the treatment of Chinese medicine preparation of the present invention be in and take as consolidation, follow up a case by regular visits to after 2 years without recurrence.
6, multitude, man, 57 years old, Chao County of Anhui Province Lakers.Patient is often constipation more than a year recently.Defecating, once, four or five days sometimes once, is eat vegetable not only but also be eat Mel, but still constipation for couple of days sometimes, and patient originally thinks that this is the common fault of old people.Have one day because stomachache, vomiting to examination in hospital, just rectal cancer has been suffered from discovery.Doctor recommends to take Chinese medicine preparation of the present invention treatment, and after taking 1 course for the treatment of, stomachache, symptoms of emesis alleviate, after taking for 2 courses for the treatment of to some extent, symptom disappears substantially, and health is clearly better, after taking 3 courses for the treatment of, transference cure, health various functions recovers normal, follows up a case by regular visits to and does not recur so far.
Claims (5)
1. treat a Chinese medicine preparation for rectal cancer, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Platycladi 32 ~ 55 portions of Fructus Artocarpi Heterophyllis 29 ~ 53 parts of Rhizoma Picrorhizae 28 ~ 52 parts of Herba Bulbophylli inconspicui 25 ~ 49 parts
18 ~ 42 parts, carambola 25 ~ 49 parts of Herba Polygoni Runcinatis 23 ~ 45 parts of Bauhinia purpureas 20 ~ 44 parts of good rattans
Rub 15 ~ 39 parts, Bai Ye 17 ~ 41 parts of bigarabes 17 ~ 41 parts purple bubble 16 ~ 40 parts of Folium Nelumbinis
Fructus Caricae 13 ~ 35 parts of Radix Puerariaes 13 ~ 31 portions of Herba Bidentis Bipinnatae 11 ~ 29 parts of Fructus Chebulaes 5 ~ 29 parts.
2. a kind of Chinese medicine preparation for the treatment of rectal cancer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Platycladi 36 ~ 51 portions of Fructus Artocarpi Heterophyllis 33 ~ 49 parts of Rhizoma Picrorhizae 32 ~ 48 parts of Herba Bulbophylli inconspicui 29 ~ 45 parts
22 ~ 38 parts, carambola 29 ~ 45 parts of Herba Polygoni Runcinatis 26 ~ 42 parts of Bauhinia purpureas 24 ~ 40 parts of good rattans
Rub 19 ~ 35 parts, Bai Ye 21 ~ 37 parts of bigarabes 21 ~ 37 parts purple bubble 20 ~ 36 parts of Folium Nelumbinis
Fructus Caricae 16 ~ 32 parts of Radix Puerariaes 16 ~ 28 portions of Herba Bidentis Bipinnatae 14 ~ 26 parts of Fructus Chebulaes 9 ~ 25 parts.
3. a kind of Chinese medicine preparation for the treatment of rectal cancer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Platycladi 40 ~ 47 portions of Fructus Artocarpi Heterophyllis 37 ~ 45 parts of Rhizoma Picrorhizae 36 ~ 44 parts of Herba Bulbophylli inconspicui 33 ~ 41 parts
26 ~ 34 parts, carambola 33 ~ 41 parts of Herba Polygoni Runcinatis 30 ~ 38 parts of Bauhinia purpureas 28 ~ 36 parts of good rattans
Rub 23 ~ 31 parts, Bai Ye 25 ~ 33 parts of bigarabes 25 ~ 33 parts purple bubble 24 ~ 32 parts of Folium Nelumbinis
Fructus Caricae 20 ~ 28 parts of Radix Puerariaes 19 ~ 25 portions of Herba Bidentis Bipinnatae 17 ~ 23 parts of Fructus Chebulaes 13 ~ 21 parts.
4. a kind of Chinese medicine preparation for the treatment of rectal cancer according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Semen Platycladi 43 portions of Fructus Artocarpi Heterophyllis 41 parts of Rhizoma Picrorhizae 40 parts of Herba Bulbophylli inconspicui 37 parts
30 parts, carambola 37 parts of Herba Polygoni Runcinatis 34 parts of Bauhinia purpureas 32 parts of good rattans
Rub 27 parts, Bai Ye 29 parts of bigarabes 29 parts purple bubble 28 parts of Folium Nelumbinis
Fructus Caricae 24 parts of Radix Puerariaes 22 portions of Herba Bidentis Bipinnatae 20 parts of Fructus Chebulaes 17 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of rectal cancer, it is characterized in that: comprise following processing step:
(1) Semen Platycladi, Fructus Artocarpi Heterophylli, carambola, Bauhinia purpurea, good rattan, Zi Pao, Folium Nelumbinis, Fructus Caricae and Fructus Chebulae are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, being condensed into relative density at 60 DEG C is the thick paste of 1.10 ~ 1.13, for subsequent use;
(2) Rhizoma Picrorhizae, bigarabe and Herba Bidentis Bipinnatae are cleaned, chopping, puts into container, strand juice, and filter impurity, stays juice for subsequent use;
(3) by Herba Bulbophylli inconspicui, Herba Polygoni Runcinati with rub Bai Ye and clean, immerse the alcohol solution dipping 1 ~ 2 hour of 80% of 5 times amount, heating extraction 3 hours, reclaims ethanol, and filter, obtain filtrate, at simmer down to 65 DEG C, relative density is the thick paste of 1.12 ~ 1.16, for subsequent use;
(4) Radix Puerariae is put into container, carry out pulverization process, grind into powder, cross 180 order fine powders, for subsequent use;
(5) by thick paste, juice and the fine powder mixing obtained by above-mentioned steps (1) ~ (4), make tablet, obtain the Chinese medicine preparation of described treatment rectal cancer.
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| CN101757567A (en) * | 2010-04-07 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating rectal cancer and preparation method thereof |
| CN103877384A (en) * | 2014-04-05 | 2014-06-25 | 柳桂玉 | Traditional Chinese medicine preparation for treating rectal cancer and preparation method thereof |
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| CN101757567A (en) * | 2010-04-07 | 2010-06-30 | 泰一和浦（北京）中医药研究院有限公司 | Traditional Chinese medicine composition for treating rectal cancer and preparation method thereof |
| CN103877384A (en) * | 2014-04-05 | 2014-06-25 | 柳桂玉 | Traditional Chinese medicine preparation for treating rectal cancer and preparation method thereof |
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Application publication date: 20150218 |