CN104352286B - Operating table for establishing rat rubrospinal tract transection animal model - Google Patents
Operating table for establishing rat rubrospinal tract transection animal model Download PDFInfo
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- CN104352286B CN104352286B CN201410715754.5A CN201410715754A CN104352286B CN 104352286 B CN104352286 B CN 104352286B CN 201410715754 A CN201410715754 A CN 201410715754A CN 104352286 B CN104352286 B CN 104352286B
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- stage body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D3/00—Appliances for supporting or fettering animals for operative purposes
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Abstract
The invention relates to an operating table for establishing a rat rubrospinal tract transection animal model. A table body is formed by sequentially arraying and splicing a first table body, a second table body and a third table body which are mutually independent, wherein the first table body and the second table body are respectively fixed on a base through a first support post and a second support post; the second table body is fixed on the base through a second support post with a vertical lifting function. During operation, the neck of the rat is driven by the second table body to ascend, so that cervical flexure is changed from a lower vertebra position to an upper vertebra position, the distance between two vertebral plates of a rat cervical is increased, and the effect that the spinal cord is convenient for operation is fully showed.
Description
Technical field
The invention belongs to operation apparatus for animal experiment, particularly to a kind of operating-table for setting up the cross-section animal model of rat tractus rubrospinalis.
Background technology
Research in terms of central nerve regeneration, its precondition broken through is to set up preferable animal model.Set up the cross-section animal model of rat tractus rubrospinalis, be typically all to use and sting except vertebral plate method exposing spinal cord.But stinging under operating microscope except vertebral plate, operation easier is bigger, it is easy to Spinal Cord, or injured blood vessel and cause massive hemorrhage, cause failure prepared by model, success rate is low.Inventor is by the dissection to rat spine, finding the vertebral plate non-overlapping copies of cervical vertebra, when normal bit (dashing forward under cervical flexure), its spacing is the least, and when cervical flexure is dashed forward upwards, its spacing is up to 2.0 mm, as long as therefore ligamenta flava cutting the effect that just can reach abundant exposing spinal cord.And when this contrary position, spinal cord and rear portion tunicle have certain tension force, are easily cut off.This easy and simple to handle, traumatic little, and maintain the integrity of spinal column, provide metastable internal environment to spinal cord of causing injury, thus model be replicated with the highest repeatability.
In existing technology, all is a levelling bench for providing the operating-table carrying out rat operation, when rat being horizontally fixed on horizontal surgery platform, its cervical vertebra is upheld naturally, is in normal bit, now prominent under cervical flexure, its spacing is the least, it is difficult to abundant exposing spinal cord, the prominent operating-table upwards of rat cervical flexure can be made so that a kind of, in order to for implementing to set up the operation of the cross-section animal model of rat tractus rubrospinalis.
Summary of the invention
The technical problem to be solved is to provide one can make rat cervical flexure prominent upwards, in order to for implementing to set up the operating-table of rat tractus rubrospinalis cross-section animal model operation.
For solving the problems referred to above, the present invention provides following technical scheme:
A kind of operating-table for setting up the cross-section animal model of rat tractus rubrospinalis, including base, stage body, described stage body is made up of the most side by side the first stage body, the second stage body and the 3rd stage body three sections；The first described stage body is fixed on described base by the first pillar；The 3rd described stage body is fixed on described base by the 3rd pillar；The second described stage body is fixed on described base by having the second pillar of vertical lift function.
As a kind of improvement to aforementioned schemes, the second described pillar includes Handleset, outer tube assembly, inner tube assembly；
Described inner tube assembly includes screw bolt seat, screw rod and inner tube, connecting base plate bottom inner tube, and the endoporus of inner tube and screw bolt seat interference fit, screw flight is rotatably connected in screw bolt seat；
Described outer tube assembly includes drive bevel gear, driven wheel of differential and outer tube, outer tube top-supported connects the second stage body, outer tube pivot bush unit is outside inner tube, Handleset is connected on outer tube sell fixed conveyor and connects the drive bevel gear in outer tube, drive bevel gear engages with the driven wheel of differential in outer tube, driven wheel of differential is fixedly connected on screw rod through back-up ring and screw, driven wheel of differential is supported on, through taper roll bearing, the bearing block upper surface being fixedly connected in outer tube, it is connected through bearing and the shaft shoulder are spacing between bearing block lower surface and screw rod, screw rod bottom is provided with the spring catch that coordinate spacing with inner tube wall.
As a kind of improvement to aforementioned schemes, the second described stage body upper surface is lined with crumpled gauze.
As a kind of improvement to aforementioned schemes, the upper surface of the first described stage body is provided with four fixing posts；The upper surface of the 3rd described stage body is provided with a fixing post.
As a kind of improvement to aforementioned schemes, the first described stage body and the upper surface of the 3rd stage body are equipped with impervious barrier, are equipped with water accepting layer on described impervious barrier.
As a kind of improvement to aforementioned schemes, the lower surface of described base is provided with sucker.
Compared with prior art, the beneficial effects of the present invention is: be made up of the first separate stage body, the second stage body and the 3rd stage body three sections by the stage body of operating-table is designed as, wherein the second stage body can be freely lifted, therefore when experiment, rat is prostrate, the lower part of the body is horizontally fixed on the first stage body, neck section is placed on the second stage body section, and head sections is horizontally fixed on the 3rd stage body section, when implementing operation, by raising the second stage body, it is achieved that make rat cervical flexure prominent upwards.The operating-table that the present invention provides can realize the table top of general surgery platform level levelling, it is also possible to realizes the rising of table top mid portion by lifting the second stage body, it is achieved makes the prominent operation table surface upwards of rat cervical flexure.
Accompanying drawing explanation
Fig. 1 is the structural representation of one embodiment of the present of invention.
Fig. 2 is the enlarged drawing of Fig. 1 local A.
Fig. 3 is the structural representation of one embodiment of the present of invention stage body.
Specific embodiment
In order to make those skilled in the art be better understood from the technical scheme of the application, below in conjunction with the accompanying drawing in the embodiment of the present application, the technical scheme in the embodiment of the present application is carried out clear, complete description.Should be appreciated that specific embodiment described herein, only in order to explain the present invention, is not intended to limit the present invention.
As it is shown in figure 1, the present invention includes base 1, stage body for the operating-table setting up the cross-section animal model of rat tractus rubrospinalis.Stage body is arranged in order split is formed by first separate stage body the 2, second stage body 3 and 4 three sections of stage bodies of the 3rd stage body.On first pillar 5, end bearing connects the first stage body 3, and lower end connects on base 1, it is achieved the first stage body 2 is fixed on base 1 by the first pillar 5.On 3rd pillar 7, end bearing connects the 3rd stage body 4, and lower end connects on base 1, it is achieved the 3rd stage body 4 is fixed on base by the 3rd pillar 7.Second stage body 3 is fixed on base 1 by having the second pillar 6 of vertical lift function.Base 1 is made up of stainless steel material, and stage body is then made up of aluminum alloy materials.Second stage body 3 is between the first stage body 2 and the 3rd stage body 4, and the width of the second stage body 3, the distance on the two articles of limits i.e. adjoining the first stage body 2 and the 3rd stage body 4 not can exceed that the neck length of rat, practice find, be advisable with the width of 1cm to 2.5cm.
As illustrated in fig. 1 and 2, the second pillar 6 includes Handleset 6.1, outer tube assembly 6.2, inner tube assembly 6.3.Inner tube assembly 6.3 includes screw bolt seat 6.16, screw rod 6.9 and inner tube 6.10, connecting base plate 1 bottom inner tube 6.10, and the endoporus of inner tube 6.10 and screw bolt seat 6.16 interference fit, screw rod 6.9 screw thread is rotatably connected in screw bolt seat 6.16；nullOuter tube assembly 6.2 includes drive bevel gear 6.4、Driven wheel of differential 6.13 and outer tube 6.8，Outer tube 6.8 top-supported connects the second stage body 3，Outer tube 6.8 pivot bush unit is outside inner tube 6.10，Handleset 6.1 is connected on outer tube 6.8 sell 6.5 fixed conveyor and connects the drive bevel gear 6.4 in outer tube 6.8，Drive bevel gear 6.4 engages with the driven wheel of differential 6.13 in outer tube 6.8，Driven wheel of differential 6.13 is fixedly connected on screw rod 6.9 through back-up ring 6.12 and screw 6.11，Driven wheel of differential 6.13 is supported on, through taper roll bearing 6.6, bearing block 6.14 upper surface being fixedly connected in outer tube 6.8，Through bearing 6.7 with the shaft shoulder 6.15 is spacing is connected between bearing block 6.14 lower surface and screw rod 6.9，Screw rod 6.9 bottom is provided with the spring catch 6.17 that coordinate spacing with inner tube 6.10 inwall.
During use, by swinging handle assembly 6.1, drive bevel gear 6.4 rotates with Handleset 6.1, driven wheel of differential 6.13 is through drive bevel gear 6.4 engagement rotation, driven wheel of differential 6.13 drives screw rod 6.9 to rotate, screw rod 6.9 upper and lower spacing through bearing block 6.14 and the shaft shoulder 6.15 respectively, and screw rod 6.9 rotates in screw bolt seat 6.16, drive outer tube 6.8 to lift in inner tube 6.10 through the shaft shoulder 6.15 and bearing block 6.14 respectively, thus drive the second stage body lifting being supported on outer tube 6.8.
During facility operation, after first rat being anaesthetized with 2% pentobarbital sodium (40 mg/ kg) intraperitoneal injection, it is placed on prostrate for rat on stage body, wherein neck section is placed on the second stage body 3, body section is placed on the first stage body 2, head is placed on the 3rd stage body 4, then fixes rat extremity and head on stage body with adhesive tape sticking, is achieved in rat ventricumbent position is fixed on stage body.Swinging handle assembly 6.1 uses the second stage body 3 to drive rat neck to rise again so that it is till cervical flexure is become upper prominent position from lower prominent position.Vertebral plate non-overlapping copies due to rat cervical vertebra, when dashing forward under normal bit i.e. cervical flexure, its spacing is the least, and when by rise the second stage body 3 drive rat neck rise make rat cervical flexure prominent upwards time, its spacing, up to 2mm, can reach the effect being easy to operation of abundant exposing spinal cord.Thus, determine operating field according to C2 spinous process, conventional under operating microscope separate soft tissue and erector spinae, expose C3, C4 vertebral arch and between ligamenta flava.Cut ligamenta flava.Owing to cervical flexure is dashed forward upward, the gap between C3 and C4 vertebral arch the most substantially expands, thus fully exposes spinal cord.Confirm spinal nerve dorsal roots, from Dorsal root connecting place the most cross-section right side spinal cord lateral funiculus, then layer-by-layer suture, operation enforcement completes.
As it is shown on figure 3, improve as a kind of, it is lined with crumpled gauze 11 at the second stage body 3 upper surface.The cervical region of rat is carried owing to the second stage body 3 is mainly used in torr, in operation, rat neck can be caused stronger compressing by the second stage body 3 rising, it is lined with soft crumpled gauze 11 at the second stage body 3 upper surface and contacts the cervical region of rat, be conducive to alleviating and rat neck is oppressed, particularly alleviate the compressing to respiratory tract, it is made to breathe smooth and easy, prostrate comfortable.And operative site is at rat neck, under it, it is lined with convenient blood and the water of absorbing of crumpled gauze 11, and reduces the infection of dust and antibacterial.Crumpled gauze 11 is laid immediately on the upper surface of the second stage body 3, and Post operation can directly abandon.
Owing to the adherence force of adhesive tape is limited, by adhesive tape sticking rat on stage body, sometimes due to anesthesia drug effect not or rat revive in advance rat struggle cause adhesive tape come off cause fixing loosely, therefore improve as a kind of, upper surface at the first stage body 2 is provided with four fixing posts 8, in order to the extremity of fixing rat；The upper surface of the 3rd described stage body 4 is provided with a fixing post 8, for fixing the head of rat.As it is shown on figure 3, the fixing post 8 being used for fixing limbs is arranged at the edge of the first stage body 2 upper surface, the fixing post 8 of the head for fixing rat is arranged at the point midway at the edge of upper surface one end of the 3rd stage body 4.During operation, it is placed on prostrate for the rat anaesthetized on stage body, extremity, front tooth before and after it is put rubber band or elastic tape respectively, is fixed on fixing post 8 and can realize rat is fixed.Further, it is also possible to simultaneously the most fixing by adhesive tape sticking auxiliary, it is achieved more firm is fixing.
Operation technique can be hindered, and hence it is also possible to fixing post 8 to be arranged at side or the lower surface of stage body owing to fixing post 8 to be arranged at the upper surface of stage body.Thus can fully expose operative site, operation technique will not be hindered because of fixing post.
As it is shown on figure 3, improve as a kind of, the upper surface of the first stage body 2 and the 3rd stage body 4 is equipped with impervious barrier 10, is equipped with water accepting layer 9 on impervious barrier 10.Impervious barrier 10 uses antiseepage cloth, is directly layed in stage body upper surface.Water accepting layer 9 uses absorbent paper, is directly layed on impervious barrier.Contaminated antiseepage cloth and absorbent paper can be directly abandoned after being finished.The fluid seepages such as blood that impervious barrier 10 can prevent from producing during rat operation, injection, reagent.Water accepting layer 9 can keep being dried of stage body, clean.
Improving as one, the lower surface at base 1 is provided with sucker.Owing to whole operating-table mass ratio is relatively light, therefore can collide the reasons such as operating-table because of experimenter unavoidably at operation process and cause operating-table to be subjected to displacement, impact operation, therefore the lower surface at base is provided with sucker, can play the effect of fixing whole operating-table.
Claims (6)
1. for setting up an operating-table for the cross-section animal model of rat tractus rubrospinalis, including base (1), stage body, it is characterised in that: described stage body is made up of the most side by side the first stage body (2), the second stage body (3) and the 3rd stage body (4) three sections；Described the first stage body (2) is fixed on described base (1) by the first pillar (5)；The 3rd described stage body (4) is fixed on described base (1) by the 3rd pillar (7)；Described the second stage body (3) is fixed on described base (1) by having second pillar (6) of vertical lift function.
Operating-table for setting up the cross-section animal model of rat tractus rubrospinalis the most according to claim 1, it is characterised in that: described the second pillar (6) includes Handleset (6.1), outer tube assembly (6.2), inner tube assembly (6.3)；
Described inner tube assembly (6.3) includes screw bolt seat (6.16), screw rod (6.9) and inner tube (6.10), inner tube (6.10) bottom connects base (1), the endoporus of inner tube (6.10) and screw bolt seat (6.16) interference fit, screw rod (6.9) screw thread is rotatably connected in screw bolt seat (6.16)；
nullDescribed outer tube assembly (6.2) includes drive bevel gear (6.4)、Driven wheel of differential (6.13) and outer tube (6.8)，Outer tube (6.8) top-supported connects the second stage body (3)，Outer tube (6.8) pivot bush unit is in inner tube (6.10) outward，Handleset (6.1) is connected on outer tube (6.8) sell (6.5) fixed conveyor and connects the drive bevel gear (6.4) in outer tube (6.8)，Drive bevel gear (6.4) engages with the driven wheel of differential (6.13) in outer tube (6.8)，Driven wheel of differential (6.13) is fixedly connected on screw rod (6.9) through back-up ring (6.12) and screw (6.11)，Driven wheel of differential (6.13) is supported on, through taper roll bearing (6.6), bearing block (6.14) upper surface being fixedly connected in outer tube (6.8)，Through bearing (6.7) with the shaft shoulder (6.15) is spacing is connected between bearing block (6.14) lower surface with screw rod (6.9)，Screw rod (6.9) bottom is provided with the spring catch (6.17) that coordinate spacing with inner tube (6.10) inwall.
Operating-table for setting up the cross-section animal model of rat tractus rubrospinalis the most according to claim 1, it is characterised in that: described the second stage body (3) upper surface is lined with crumpled gauze (11).
4. according to the operating-table for setting up the cross-section animal model of rat tractus rubrospinalis described in any one of claims 1 to 3, it is characterized in that: the upper surface at described the first stage body (2) is provided with four fixing posts (8), the upper surface at the 3rd described stage body (4) is provided with a fixing post (8).
Operating-table for setting up the cross-section animal model of rat tractus rubrospinalis the most according to claim 1, it is characterized in that: described the first stage body (2) and the upper surface of the 3rd stage body (4) are equipped with impervious barrier (10), are equipped with water accepting layer (9) on described impervious barrier (10).
Operating-table for setting up the cross-section animal model of rat tractus rubrospinalis the most according to claim 1, it is characterised in that: the lower surface of described base (1) is provided with sucker.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410715754.5A CN104352286B (en) | 2014-12-02 | 2014-12-02 | Operating table for establishing rat rubrospinal tract transection animal model |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410715754.5A CN104352286B (en) | 2014-12-02 | 2014-12-02 | Operating table for establishing rat rubrospinal tract transection animal model |
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| CN104352286A CN104352286A (en) | 2015-02-18 |
| CN104352286B true CN104352286B (en) | 2017-01-11 |
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| CN201410715754.5A Expired - Fee Related CN104352286B (en) | 2014-12-02 | 2014-12-02 | Operating table for establishing rat rubrospinal tract transection animal model |
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| CN105105864B (en) * | 2015-09-18 | 2017-04-05 | 山东大学齐鲁医院 | A kind of half cross-section modeling device of dismountable rat spinal cord left/right |
| CN105455918B (en) * | 2016-01-19 | 2017-04-12 | 浙江中医药大学 | Operation table suitable for rat waist and back fine operation |
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| CN108670496A (en) * | 2018-02-07 | 2018-10-19 | 福州市第二医院（福建省福州中西医结合医院、福州市职业病医院） | A kind of experimental animal protrusion of lumber intervertebral disc fibrous ring suture model and combinations thereof tool |
| CN109077825B (en) * | 2018-08-02 | 2023-12-05 | 中国人民解放军第二军医大学第二附属医院 | Tension stimulation device for inducing rat thoracolumbar yellow ligament ossification and application thereof |
| CN110680553A (en) * | 2019-11-14 | 2020-01-14 | 南京市中医院 | Adjustable operation panel suitable for rat brain stereotaxic apparatus |
| CN110680554B (en) * | 2019-11-18 | 2024-09-17 | 上海市普陀区人民医院 | Experimental animal modeling component for focal permanent cerebral ischemia |
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| CN87205479U (en) * | 1987-11-24 | 1988-11-09 | 阳泉矿务局医院 | Operation table for spinal traction |
| US5147287A (en) * | 1991-03-18 | 1992-09-15 | Ohio Medical Instrument Company | Neck support means for cervical surgery |
| US6102882A (en) * | 1996-04-15 | 2000-08-15 | Cobo; Bernabe Cobo | Physiotherapy apparatus for the treatment of articular stiffness |
| US9009894B2 (en) * | 2007-09-20 | 2015-04-21 | Posture Correction Tools, LLC | Chiropractic posture correction tool |
| CN101601619B (en) * | 2009-06-26 | 2011-01-12 | 张德宏 | Multi-functional electric traction, rectification and recovery bed |
| WO2012076660A1 (en) * | 2010-12-08 | 2012-06-14 | Universiteit Antwerpen | Animal positioning for in-vivo imaging |
| CN202920405U (en) * | 2012-10-18 | 2013-05-08 | 上海市东方医院 | Animal four-limb fixing device of small animal ultrasonic device heating plate |
| CN103892931A (en) * | 2012-12-26 | 2014-07-02 | 深圳先进技术研究院 | Mouse experiment operating table |
| CN203042535U (en) * | 2013-01-19 | 2013-07-10 | 佳木斯大学 | Animal operating table |
| CN203122667U (en) * | 2013-02-26 | 2013-08-14 | 张成训 | Fixing frame for livestock operation |
| CN203317397U (en) * | 2013-04-28 | 2013-12-04 | 谢翠斌 | Screw adjustable lift type working table |
| CN103284812A (en) * | 2013-06-29 | 2013-09-11 | 吴爱悯 | Outer fixing support for spinal cord injury animal experiments |
| CN204274709U (en) * | 2014-12-02 | 2015-04-22 | 湖南中医药大学 | A kind of operating-table for setting up the cross-section animal model of rat tractus rubrospinalis |
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