CN104352217A - Esophagus OCT system and application method thereof - Google Patents

Esophagus OCT system and application method thereof Download PDF

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Publication number
CN104352217A
CN104352217A CN201410559897.1A CN201410559897A CN104352217A CN 104352217 A CN104352217 A CN 104352217A CN 201410559897 A CN201410559897 A CN 201410559897A CN 104352217 A CN104352217 A CN 104352217A
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CN
China
Prior art keywords
oct
esophagus
seal wire
oct system
piu
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Pending
Application number
CN201410559897.1A
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Chinese (zh)
Inventor
沈诚亮
刘海平
李青云
邬烈辉
吕杰杰
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Shenzhen Vivolight Medical Device Technology Co Ltd
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Shenzhen Vivolight Medical Device Technology Co Ltd
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Priority to CN201410559897.1A priority Critical patent/CN104352217A/en
Publication of CN104352217A publication Critical patent/CN104352217A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062Arrangements for scanning
    • A61B5/0066Optical coherence imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/273Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
    • A61B1/2733Oesophagoscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/273Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
    • A61B1/2736Gastroscopes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00273Anchoring means for temporary attachment of a device to tissue
    • A61B2018/00279Anchoring means for temporary attachment of a device to tissue deployable
    • A61B2018/00285Balloons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/10Balloon catheters

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Optics & Photonics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Endoscopes (AREA)

Abstract

The invention relates to an esophagus OCT (Optical Coherence Tomography) system which comprises an OCT engine, a PIU (Probe Interface Unit), a balloon catheter, an OCT guide wire with a probe, a high-speed acquisition device and an image processing and displaying device which are connected in sequence. The esophagus OCT system is capable of solving the problems that the conventional Barrets Esophagus (BE) diagnostic equipment is low in rate of return, the diagnosis is delayed and the sampling has errors, has the advantages of high imaging speed, high resolution, high contrast and easiness in image identification, and is capable of satisfying the practical medical work requirements of the clinical doctors for observing the esophagus organization characteristics and the like.

Description

A kind of esophagus OCT system and using method thereof
Technical field
The invention belongs to technical field of medical equipment, relate to a kind of scanning system, particularly relate to a kind of esophagus OCT (Optical Coherence Tomography, optical coherence tomography) system and using method thereof.
Background technology
At present, in each disease increasing cancer stricken risk, Barrett esophagus is typical disease.Barrett esophagus (Barrett) is the state produced the day after tomorrow, is the result of gastric reflux.Although Barrett esophagus is easy to by endoscope check, for diagnosing clearly, microscope biopsy must be carried out to involved tissue.Endoscopy is the unique way that can be used for diagnosing Barrett esophagus at present.Its limitation is lower return rate, higher survey fee use, and diagnosis exists delay, and sampling exists error etc.Therefore can solve prior art limitation in the urgent need to one, meet the new technique of actual medical work.
Summary of the invention
One aspect of the present invention provides a kind of esophagus OCT system, comprises the OCT engine, PIU, foley's tube, the OCT seal wire containing probe that connect successively, high speed acquisition device and image procossing and display device; The laser of OCT engine is passed to OCT seal wire through PIU, and OCT seal wire is driven by PIU, pulls back at a slow speed in foley's tube while high speed rotating.
In above scheme preferably, described balloon catheter device comprises interposing catheter, and one end of described interposing catheter is provided with inflation inlet and OCT seal wire introducing port, and the other end of described interposing catheter is provided with inflating balloon.
Can also preferably, described esophagus OCT system needs to peep gastroscope by interior; Peep gastroscope in described and be provided with pincers road junction, foley's tube and OCT seal wire successively enter in esophagus by pincers road; Sacculus stretches out pincers road junction far-end, opens after being inflated and supports esophagus, is at this moment inserted by seal wire and probe is positioned at sacculus opened part.
Can also preferably, described OCT engine is integrated into picture coupling and optical signal is converted into the signal of telecommunication; The workflow of described OCT engine is: first light source is divided into two paths of signals, and a road is as the signal with reference to arm, and another road is as the signal of sample arm, and the equivalent optical path of two paths of signals, to form interference signal; Balance photodetector detects the light echo of reference arm and sample arm and carries out difference processing, finally interference signal is sent to high speed acquisition device and samples.
Can also preferably, described light source provides centre wavelength 1310nm, and the stabilized light source of bandwidth 140nm exports, simultaneously for high-speed figure collection provides triggering signal; Described high speed acquisition device carries out date processing and data analysis; Pull back at a slow speed while described PIU high speed rotating.
Can also preferably, described image procossing and display device adopt host computer; Described host computer acquisition and processing data, and it is analyzed and measures, then by data back to display; Described esophagus OCT system also comprises display.
The present invention provides a kind of using method of esophagus OCT system on the other hand, step comprises: first peep before gastroscope inserts patient esophagus to surveyed area by interior, peep the pincers road junction of gastroscope in being inserted by foley's tube and be fixed on pincers one end, road junction, and guaranteeing that sacculus passes gastroscope pincers road junction; Then start from the inflation inlet of catheter proximal end to inflated, after, insert OCT seal wire from conduit introducing port, and guarantee that seal wire front-end probe arrives detection position; Be fixed in the draw-in groove of PIU by the near-end of conduit and seal wire again, seal wire can be pulled back at a slow speed while high speed rotating under PIU drives.Diagnosis of scans is carried out to the esophageal wall of relevant position and deep tissues thereof in probe place of arrival namely; OCT engine accepts interference signal is also delivered to signal pickup assembly, and image is also presented on screen by host computer process data in real time.
Compared with prior art, the present invention has the following advantages:
A kind of esophagus OCT system of the present invention and using method thereof, can solve that return rate existing for existing diagnosis Barrett esophagus equipment is low, cost is high, the problem such as Delay in Diagnosis and sampling error, there is the advantages such as realtime imaging, resolution is high, contrast is strong, clinician can be met to actual medical requirements of one's work such as the requirements of esophageal tissue observation of characteristics.
Accompanying drawing explanation
Below in conjunction with drawings and embodiments, the invention will be further described:
Fig. 1 is the structural representation of esophagus OCT system of the present invention;
Fig. 2 is the structural representation of the balloon catheter device of esophagus OCT system of the present invention.
In figure, 1 is swept light source, and 2 is OCT engine, and 3 is high speed acquisition device, and 4 is image procossing and display device, and 5 is PIU, and 6 is OCT conduit, and 7 is probe, and 8 is inflation inlet, and 9 is OCT conduit introducing port, and 10 is inflating balloon; 11 is interposing catheter.
Detailed description of the invention
In order to understand the present invention better, below in conjunction with specific embodiment, the present invention is explained in detail.But, obviously can carry out different modification and remodeling to the present invention and not exceed the wider spirit and scope of the present invention of appended claims.Therefore, following examples have exemplary and hard-core implication.
Embodiment 1
A kind of esophagus OCT system, comprise swept light source 1, OCT engine 2, high speed acquisition device 3 and the image procossing and display device 4 that connect successively, it is characterized in that: described OCT engine 2 is also connected with PIU5, and namely process proceeds to unit, and described PIU5 is connected with OCT conduit 6 again; The end of described OCT conduit 6 is provided with the probe 7 of kernel high speed rotating.
Embodiment 2
A kind of esophagus OCT system, similar to embodiment 1, difference is, described OCT engine 2 is integrated into picture coupling and optical signal is converted into signal; The workflow of described OCT engine 2 is: first light source is divided into two paths of signals, and a road is the light source of reference arm, and another road is the equivalent optical path of the light source of sample arm, two paths of signals, to form interference signal; Then detected the light echo of reference arm and sample arm by detector, then carry out difference processing, finally primary signal is sent to high speed acquisition device 3 and samples; Described conduit detecting object also participates in light path coupling; Described swept light source 1 provides centre wavelength 1310nm, and the stabilized light source of bandwidth 140nm exports, simultaneously for high-speed figure collection provides synchronous triggering signal; Described high speed acquisition device 3 carries out date processing and data analysis; Described PIU5 provides stable rotation at a high speed and pulling back at a slow speed; Described image procossing and display device 4 adopt host computer; Described host computer carry out date processing, obtain gather data, then by data back to display, finally data analysis and measurement are carried out to image.
Embodiment 3
A kind of esophagus OCT system, similar to embodiment 2, difference is, described conduit adopts balloon catheter device; Described balloon catheter device comprises interposing catheter 11, and one end of described interposing catheter 11 is provided with inflation inlet 8 and OCT conduit introducing port 9, and the other end of described interposing catheter 11 is provided with inflating balloon 10; Gastroscope is peeped in described esophagus OCT system also comprises; Peep gastroscope in described and be provided with pincers road junction; Described balloon catheter device is peeped the pincers road junction of gastroscope and is fixed on pincers one end, road junction in inserting, peep the pincers road junction of gastroscope in the probe 7 of its front end of probe of described balloon catheter device passes.
Embodiment 4
A kind of using method of esophagus OCT system as described in Example 4, first interior gastroscope of peeping is inserted esophagus, then peep the pincers road junction of gastroscope in balloon catheter device being inserted and be fixed on pincers one end, road junction, making the probe 7 of its front end of probe of balloon catheter device pass gastroscope pincers road junction, then start to inflate to inflating balloon 10 from the inflation inlet 8 of balloon catheter device, simultaneously by the location aerification function of pressure transducer and pedal on-off control inflating balloon 10, after inflating balloon 10 is full of, stop inflation by pressure transducer feedback data to main frame, after inflation, OCT conduit 6 is inserted from OCT conduit introducing port 9, when OCT conduit 6 enters arrival probe portion position, described PIU5 control OCT conduit 6, stable high speed rotating is provided, OCT conduit 6 is pulled back imaging, the esophageal wall of the probe 7 rotation sweep diseased region of process of pulling back end of probe, complete and diagnosis of scans is carried out to esophagus table wall deep layer, then tomography heliogram is returned to OCT engine 2 through PIU5, again by high speed acquisition device 3 acquired signal, and the data gathered are obtained by main frame, be resent to image procossing and image real time transfer and analysis are carried out in display device 4, finally diagnostic image is imaged on display.
Although be below described various preferred implementation of the present invention and feature, under the prerequisite not departing from object of the present invention and aim, those of ordinary skill in the art can make many changes to the present invention, supplement, change and delete.More than in conjunction with the detailed description that specific embodiments of the invention are done, it is not limitation of the present invention.Every according to technical spirit of the present invention to any simple modification made for any of the above embodiments, all still belong to the scope of technical solution of the present invention.

Claims (7)

1. an esophagus OCT system, comprises the OCT engine, PIU, foley's tube, the OCT seal wire with probe that connect successively, high speed acquisition device and image procossing and display device; It is characterized in that: the laser of OCT engine is passed to OCT seal wire through PIU, and OCT seal wire is driven by PIU, in foley's tube, do linear uniform motion while high speed rotating.
2. esophagus OCT system as claimed in claim 1, it is characterized in that: described balloon catheter device comprises interposing catheter, one end of described interposing catheter is provided with inflation inlet and OCT seal wire introducing port, and the other end of described interposing catheter is provided with inflating balloon.
3. esophagus OCT system as claimed in claim 2, is characterized in that: described esophagus OCT system needs peep gastroscope by interior; Peep gastroscope in described and be provided with pincers road junction, foley's tube and OCT seal wire successively enter in esophagus by pincers road; Sacculus stretches out pincers road junction far-end, opens after being inflated and supports esophagus, is at this moment inserted by seal wire and probe is positioned at sacculus opened part.
4. esophagus OCT system as claimed in claim 1, is characterized in that: described OCT engine is integrated into picture coupling and optical signal is converted into the signal of telecommunication; The workflow of described OCT engine is: first light source is divided into two paths of signals, and a road is as the signal with reference to arm, and another road is as the signal of sample arm, and the equivalent optical path of two paths of signals, to form interference signal; Balance photodetector detects the light echo of reference arm and sample arm and carries out difference processing, finally interference signal is sent to high speed acquisition device and samples.
5. esophagus OCT system as claimed in claim 4, is characterized in that: described light source provides centre wavelength 1310nm, and the stabilized light source of bandwidth 140nm exports, simultaneously for high-speed figure collection provides triggering signal; Described high speed acquisition device carries out date processing and data analysis; Pull back at a slow speed while described PIU high speed rotating.
6. the esophagus OCT system as described in claim 1 or 4 or 5, is characterized in that: described image procossing and display device adopt host computer; Described host computer acquisition and processing data, and it is analyzed and measures, then by data back to display; Described esophagus OCT system also comprises display.
7. a using method for esophagus OCT system, step comprises: first peep before gastroscope inserts patient esophagus to surveyed area by interior, will foley's tube insert in peep the pincers road junction of gastroscope and be fixed on pincers one end, road junction, and guarantee that sacculus passes gastroscope pincers road junction; Then start from the inflation inlet of catheter proximal end to inflated, after, insert OCT seal wire from conduit introducing port, and guarantee that seal wire front-end probe arrives detection position; Be fixed in the draw-in groove of PIU by the near-end of conduit and seal wire again, seal wire can be pulled back at a slow speed while high speed rotating under PIU drives.Diagnosis of scans is carried out to the esophageal wall of relevant position and deep tissues thereof in probe place of arrival namely; OCT engine accepts interference signal is also delivered to signal pickup assembly, and image is also presented on screen by host computer process data in real time.
CN201410559897.1A 2014-10-21 2014-10-21 Esophagus OCT system and application method thereof Pending CN104352217A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016180289A1 (en) * 2015-05-08 2016-11-17 南京微创医学科技有限公司 Application of automatic inflation/deflation device in oct endoscopic scanning and imaging system
CN106691385A (en) * 2016-12-29 2017-05-24 天津恒宇医疗科技有限公司 Support frame OCT imaging duct
CN114159029A (en) * 2021-11-30 2022-03-11 深圳先进技术研究院 Optical coherence tomography system and imaging catheter thereof
WO2022135371A1 (en) * 2020-12-21 2022-06-30 王天龙 Near-infrared spectrum continuous esophageal tissue oxygen saturation monitor

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CN102697451A (en) * 2012-01-18 2012-10-03 广州宝胆医疗器械科技有限公司 Optical coherence tomography (OCT) electronic bronchoscope system
CN103040428A (en) * 2013-01-05 2013-04-17 无锡微奥科技有限公司 Optical scanning probe for endoscopic OCT (optical coherence tomography) imaging
CN204072038U (en) * 2014-09-02 2015-01-07 乐普(北京)医疗器械股份有限公司 OCT endoscopic imaging probe and OCT imaging catheter
CN105263386A (en) * 2013-05-29 2016-01-20 住友电气工业株式会社 Catheter for optical coherence tomograph, and catheter production method

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US20020188204A1 (en) * 2001-06-07 2002-12-12 Mcnamara Edward I. Fiber optic endoscopic gastrointestinal probe
WO2002100258A1 (en) * 2001-06-07 2002-12-19 Lightlab Imaging, Llc Fiber optic endoscopic gastrointestinal probe
CN1593351A (en) * 2004-06-28 2005-03-16 天津大学 Medical mini supersonic -OCT probe via endoscope
CN101051232A (en) * 2006-06-09 2007-10-10 四川大学华西医院 Automatic regulating and controlling instrument for pressure in catheter saccule
CN102469940A (en) * 2009-07-01 2012-05-23 阿维格公司 Catheter-based off-axis optical coherence tomography imaging system
US20120004506A1 (en) * 2010-06-03 2012-01-05 The General Hospital Corporation Apparatus and method for devices for imaging structures in or at one or more luminal organs
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016180289A1 (en) * 2015-05-08 2016-11-17 南京微创医学科技有限公司 Application of automatic inflation/deflation device in oct endoscopic scanning and imaging system
CN106691385A (en) * 2016-12-29 2017-05-24 天津恒宇医疗科技有限公司 Support frame OCT imaging duct
WO2022135371A1 (en) * 2020-12-21 2022-06-30 王天龙 Near-infrared spectrum continuous esophageal tissue oxygen saturation monitor
CN114159029A (en) * 2021-11-30 2022-03-11 深圳先进技术研究院 Optical coherence tomography system and imaging catheter thereof

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Inventor after: Zhu Rui

Inventor after: Shen Chengliang

Inventor after: Liu Haiping

Inventor after: Li Qingyun

Inventor after: Wu Liehui

Inventor after: Lv Jiejie

Inventor before: Shen Chengliang

Inventor before: Liu Haiping

Inventor before: Li Qingyun

Inventor before: Wu Liehui

Inventor before: Lv Jiejie

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: SHEN CHENGLIANG LIU HAIPING LI QINGYUN WU LIEHUI LV JIEJIE TO: ZHU RUI SHEN CHENGLIANG LIU HAIPING LI QINGYUN WU LIEHUI LV JIEJIE

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Application publication date: 20150218